Harvard Catalyst Profiles

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Buthionine Sulfoximine

"Buthionine Sulfoximine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A synthetic amino acid that depletes glutathione by irreversibly inhibiting gamma-glutamylcysteine synthetase. Inhibition of this enzyme is a critical step in glutathione biosynthesis. It has been shown to inhibit the proliferative response in human T-lymphocytes and inhibit macrophage activation. (J Biol Chem 1995;270(33):1945-7)


This graph shows the total number of publications written about "Buthionine Sulfoximine" by people in Harvard Catalyst Profiles by year, and whether "Buthionine Sulfoximine" was a major or minor topic of these publication.
Bar chart showing 11 publications over 9 distinct years, with a maximum of 2 publications in 1991 and 1998
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.