Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Antibody Affinity

"Antibody Affinity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes.


This graph shows the total number of publications written about "Antibody Affinity" by people in Harvard Catalyst Profiles by year, and whether "Antibody Affinity" was a major or minor topic of these publication.
Bar chart showing 167 publications over 30 distinct years, with a maximum of 11 publications in 2014 and 2016
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.