"1,2-Dimethylhydrazine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
Concept/Terms
1,2-Dimethylhydrazine- 1,2-Dimethylhydrazine
- 1,2 Dimethylhydrazine
- 1,2-Dimethyl-hydrazine
- 1,2 Dimethyl hydrazine
- N,N'-Dimethylhydrazine
- N,N' Dimethylhydrazine
Below are MeSH descriptors whose meaning is more general than "1,2-Dimethylhydrazine".
Below are MeSH descriptors whose meaning is more specific than "1,2-Dimethylhydrazine".
This graph shows the total number of publications written about "1,2-Dimethylhydrazine" by people in Harvard Catalyst Profiles by year, and whether "1,2-Dimethylhydrazine" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2005 | 0 | 1 | 1 |
2016 | 1 | 0 | 1 |
Below are the most recent publications written about "1,2-Dimethylhydrazine" by people in Profiles.
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Protective effect of metformin in an aberrant crypt foci model induced by 1,2-dimethylhydrazine: Modulation of oxidative stress and inflammatory process. Mol Carcinog. 2017 03; 56(3):913-922.
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Melatonin modulated autophagy and Nrf2 signaling pathways in mice with colitis-associated colon carcinogenesis. Mol Carcinog. 2016 Mar; 55(3):255-67.
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Wild-type K-ras has a tumour suppressor effect on carcinogen-induced murine colorectal adenoma formation. Int J Exp Pathol. 2014 Feb; 95(1):8-15.
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The protective role of Lychnophora ericoides Mart. (Brazilian arnica) in 1,2-dimethylhydrazine-induced experimental colon carcinogenesis. Nutr Cancer. 2011; 63(4):593-9.
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Mutant K-ras promotes carcinogen-induced murine colorectal tumourigenesis, but does not alter tumour chromosome stability. J Pathol. 2011 Feb; 223(3):390-9.
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Folate deficiency provides protection against colon carcinogenesis in DNA polymerase beta haploinsufficient mice. J Biol Chem. 2010 Jun 18; 285(25):19246-58.
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K-ras exon 4A has a tumour suppressor effect on carcinogen-induced murine colonic adenoma formation. J Pathol. 2010 Apr; 220(5):542-50.
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Detection of initiation activity of 1,2-dimethylhydrazine in in vivo medium-term liver initiation assay system using 4-week-old rats without hepatocellular proliferative stimuli during the test chemical treatment period. J Vet Med Sci. 2010 Jan; 72(1):43-53.
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Targeting normal and neoplastic tissues in the rat jejunum and colon with boronated, cationic acrylamide copolymers. J Control Release. 2005 Aug 18; 106(1-2):14-25.
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The Cables gene on chromosome 18Q regulates colon cancer progression in vivo. Cancer Biol Ther. 2005 Aug; 4(8):861-3.