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Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements.
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Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements.
Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements. PLoS Biol. 2008 Oct 21; 6(10):e257.
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PubMed
subject areas
Amyloid Precursor Protein Secretases
Animals
Cell Line
Cells, Cultured
Chromatography, Liquid
Dimethyl Sulfoxide
Electrophoresis, Polyacrylamide Gel
Enzyme Activation
gamma-Aminobutyric Acid
HeLa Cells
Humans
Immunoblotting
Immunoprecipitation
Mice
Proteomics
Substrate Specificity
Tandem Mass Spectrometry
Triglycerides
authors with profiles
Steven P. Gygi, Ph.D.
Matthew Louis Hemming, M.D., Ph.D.
Dennis J. Selkoe, M.D.