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Comments on 'Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers' by M. J. Pencina, R. B. D'Agostino, Sr. and E. W. Steyerberg.

Cook NR, Paynter NP. Comments on 'Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers' by M. J. Pencina, R. B. D'Agostino, Sr. and E. W. Steyerberg. Stat Med. 2012 Jan 13; 31(1):93-5; author reply 96-7.

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.