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Progranulin protects against amyloid ß deposition and toxicity in Alzheimer's disease mouse models.
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Progranulin protects against amyloid ß deposition and toxicity in Alzheimer's disease mouse models.
Progranulin protects against amyloid ß deposition and toxicity in Alzheimer's disease mouse models. Nat Med. 2014 Oct; 20(10):1157-64.
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PubMed
subject areas
Alzheimer Disease
Amyloid beta-Peptides
Animals
Brain
Cognition
Disease Models, Animal
Female
Frontotemporal Lobar Degeneration
Gene Expression Regulation
Humans
Immunity, Innate
Intercellular Signaling Peptides and Proteins
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Mice, Transgenic
Microglia
Phagocytosis
Plaque, Amyloid
Rats
Up-Regulation
authors with profiles
Robert V. Farese Jr., M.D.