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Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.
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Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.
Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury. J Clin Invest. 2012 11; 122(11):3955-9.
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PubMed
subject areas
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Animals
Cell Death
Cells, Cultured
Cerebral Cortex
Frontotemporal Dementia
Humans
Inflammation
Intercellular Signaling Peptides and Proteins
Interferon-gamma
Lipopolysaccharides
Mice
Mice, Knockout
Microglia
MPTP Poisoning
Nerve Tissue Proteins
Neurons
Neurotoxins
authors with profiles
Robert V. Farese Jr., M.D.