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CRM1 and BRAF inhibition synergize and induce tumor regression in BRAF-mutant melanoma.
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CRM1 and BRAF inhibition synergize and induce tumor regression in BRAF-mutant melanoma.
CRM1 and BRAF inhibition synergize and induce tumor regression in BRAF-mutant melanoma. Mol Cancer Ther. 2013 Jul; 12(7):1171-9.
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PubMed
subject areas
Animals
Apoptosis
Cell Line, Tumor
Cell Proliferation
Humans
Karyopherins
Melanoma
Mice
Mice, Nude
Proto-Oncogene Proteins B-raf
Receptors, Cytoplasmic and Nuclear
Tumor Suppressor Protein p53
Xenograft Model Antitumor Assays
authors with profiles
Keith Thomas Flaherty, M.D.
James C. Cusack Jr., M.D.
Hensin Tsao, M.D., Ph.D.