Glomerulosclerosis, Focal Segmental
"Glomerulosclerosis, Focal Segmental" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.
MeSH Number(s)
C12.777.419.570.363.660
C13.351.968.419.570.363.640
Concept/Terms
Glomerulosclerosis, Focal Segmental- Glomerulosclerosis, Focal Segmental
- Segmental Glomerulosclerosis, Focal
- Glomerulosclerosis, Focal
- Focal Glomerulosclerosis
- Focal Segmental Glomerulosclerosis
- Glomerulonephritis, Focal Sclerosing
- Focal Sclerosing Glomerulonephritides
- Focal Sclerosing Glomerulonephritis
- Glomerulonephritides, Focal Sclerosing
- Sclerosing Glomerulonephritides, Focal
- Sclerosing Glomerulonephritis, Focal
Hyalinosis, Segmental Glomerular- Hyalinosis, Segmental Glomerular
- Glomerular Hyalinosis, Segmental
- Segmental Glomerular Hyalinosis
- Hyalinosis, Segmental
- Segmental Hyalinosis
Below are MeSH descriptors whose meaning is more general than "Glomerulosclerosis, Focal Segmental".
Below are MeSH descriptors whose meaning is more specific than "Glomerulosclerosis, Focal Segmental".
This graph shows the total number of publications written about "Glomerulosclerosis, Focal Segmental" by people in Harvard Catalyst Profiles by year, and whether "Glomerulosclerosis, Focal Segmental" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 2 | 4 |
| 1996 | 1 | 0 | 1 |
| 1997 | 2 | 2 | 4 |
| 1998 | 4 | 1 | 5 |
| 1999 | 3 | 1 | 4 |
| 2000 | 5 | 0 | 5 |
| 2001 | 5 | 0 | 5 |
| 2002 | 5 | 1 | 6 |
| 2003 | 0 | 1 | 1 |
| 2004 | 4 | 1 | 5 |
| 2005 | 2 | 0 | 2 |
| 2006 | 1 | 1 | 2 |
| 2007 | 10 | 1 | 11 |
| 2008 | 4 | 1 | 5 |
| 2009 | 10 | 0 | 10 |
| 2010 | 3 | 1 | 4 |
| 2011 | 9 | 3 | 12 |
| 2012 | 2 | 1 | 3 |
| 2013 | 10 | 3 | 13 |
| 2014 | 7 | 0 | 7 |
| 2015 | 5 | 2 | 7 |
| 2016 | 5 | 1 | 6 |
| 2017 | 6 | 1 | 7 |
| 2018 | 9 | 2 | 11 |
| 2019 | 7 | 2 | 9 |
| 2020 | 12 | 5 | 17 |
| 2021 | 6 | 3 | 9 |
| 2022 | 8 | 1 | 9 |
| 2023 | 8 | 0 | 8 |
Below are the most recent publications written about "Glomerulosclerosis, Focal Segmental" by people in Profiles.
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Post-transplant recurrence of focal segmental glomerular sclerosis: consensus statements. Kidney Int. 2024 Mar; 105(3):450-463.
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Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease. Nat Commun. 2023 Nov 30; 14(1):7836.
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Sparsentan - Another Arrow in the Quiver for Treatment of FSGS? N Engl J Med. 2023 Dec 28; 389(26):2482-2483.
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The association of low birthweight and prematurity on outcomes in children and adults with nephrotic syndrome-a NEPTUNE cohort study. Pediatr Nephrol. 2023 10; 38(10):3297-3308.
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Inaxaplin for Proteinuric Kidney Disease in Persons with Two APOL1 Variants. N Engl J Med. 2023 Mar 16; 388(11):969-979.
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Decay-Accelerating Factor Expression Modulates the Severity of Experimental Focal Segmental Glomerulosclerosis. Kidney360. 2023 03 01; 4(3):381-386.
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The role of HLA antigens in recurrent primary focal segmental glomerulosclerosis. Front Immunol. 2023; 14:1124249.
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The small GTPase regulatory protein Rac1 drives podocyte injury independent of cationic channel protein TRPC5. Kidney Int. 2023 06; 103(6):1056-1062.
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Nephrotic Syndrome Gene TBC1D8B Is Required for Endosomal Maturation and Nephrin Endocytosis in Drosophila. J Am Soc Nephrol. 2022 12; 33(12):2174-2193.
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Is it Time to Re-Evaluate Our Experimental Approach to Studying Diffuse Podocytopathies? J Am Soc Nephrol. 2022 11; 33(11):1959-1960.