Mitochondrial Diseases

"Mitochondrial Diseases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.

Descriptor ID

D028361

MeSH Number(s)

C18.452.660

Concept/Terms

Mitochondrial Diseases

Oxidative Phosphorylation Deficiencies

Respiratory Chain Deficiencies, Mitochondrial

Electron Transport Chain Deficiencies, Mitochondrial

Below are MeSH descriptors whose meaning is more general than "Mitochondrial Diseases".

Diseases [C]
Nutritional and Metabolic Diseases [C18]
Metabolic Diseases [C18.452]
Mitochondrial Diseases [C18.452.660]

Below are MeSH descriptors whose meaning is related to "Mitochondrial Diseases".

Below are MeSH descriptors whose meaning is more specific than "Mitochondrial Diseases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mitochondrial Diseases" by people in Harvard Catalyst Profiles by year, and whether "Mitochondrial Diseases" was a major or minor topic of these publication.

Bar chart showing 201 publications over 22 distinct years, with a maximum of 21 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	3	4
2003	1	3	4
2004	6	1	7
2006	1	2	3
2007	1	1	2
2008	5	1	6
2009	5	4	9
2010	6	2	8
2011	1	3	4
2012	7	0	7
2013	17	4	21
2014	11	1	12
2015	5	3	8
2016	9	3	12
2017	10	4	14
2018	10	2	12
2019	10	4	14
2020	10	4	14
2021	13	2	15
2022	8	2	10
2023	11	0	11
2024	4	0	4

Below are the most recent publications written about "Mitochondrial Diseases" by people in Profiles.

Circulating N-lactoyl-amino acids and N-formyl-methionine reflect mitochondrial dysfunction and predict mortality in septic shock. Metabolomics. 2024 Mar 06; 20(2):36.

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Advancing the neuroimaging diagnosis and understanding of mitochondrial disorders. Neurotherapeutics. 2024 Jan; 21(1):e00324.

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IL-15 reprogramming compensates for NK cell mitochondrial dysfunction in HIV-1 infection. JCI Insight. 2024 Jan 16; 9(4).

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Brown adipose tissue CoQ deficiency activates the integrated stress response and FGF21-dependent mitohormesis. EMBO J. 2024 Jan; 43(2):168-195.

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Striated preferentially expressed gene deficiency leads to mitochondrial dysfunction in developing cardiomyocytes. Basic Res Cardiol. 2024 Feb; 119(1):151-168.

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Endocrine features of primary mitochondrial diseases. Curr Opin Endocrinol Diabetes Obes. 2024 Feb 01; 31(1):34-42.

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Tetracyclines activate mitoribosome quality control and reduce ER stress to promote cell survival. EMBO Rep. 2023 Dec 06; 24(12):e57228.

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Optimized Nutrition in Mitochondrial Diseases Correlates with Improved Muscle Fatigue, Strength, and Quality of Life: You Are What You Eat, or Are You? Neurotherapeutics. 2023 Oct; 20(6):1694-1695.

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Expert Panel Curation of 113 Primary Mitochondrial Disease Genes for the Leigh Syndrome Spectrum. Ann Neurol. 2023 10; 94(4):696-712.

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Novel homozygous variants in PRORP expand the genotypic spectrum of combined oxidative phosphorylation deficiency 54. Eur J Hum Genet. 2023 10; 31(10):1190-1194.

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