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Stephanie Mohr, PH.D.

TitleLecturer on Genetics
InstitutionHarvard Medical School
DepartmentGenetics
AddressHarvard Medical School
Dept of Genetics
77 Avenue Louis Pasteur
Boston MA 02115
Phone617/432-5626

 Research 
 research resources
This researcher has shared information about their research resources
in the eagle-i Network. To update or add resource records, contact
eagle-i@hms.harvard.edu.
Drosophila RNAi Screening Center (HMS) - Core services (6), Instruments (6) and Plasmids (3875)
Genome Engineering Production Group (HMS) - Core services (4) and Instruments (1)

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Mohr SE, Smith JA, Shamu CE, Neumüller RA, Perrimon N. RNAi screening comes of age: improved techniques and complementary approaches. Nat Rev Mol Cell Biol. 2014 Aug 22; 15(9):591-600.
    View in: PubMed
  2. Yilmazel B, Hu Y, Sigoillot F, Smith JA, Shamu CE, Perrimon N, Mohr SE. Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis. BMC Bioinformatics. 2014; 15:192.
    View in: PubMed
  3. Zhou R, Mohr S, Hannon GJ, Perrimon N. Inducing RNAi in Drosophila Cells by Soaking with dsRNA. Cold Spring Harb Protoc. 2014; 2014(5).
    View in: PubMed
  4. Mohr SE, Hu Y, Kim K, Housden BE, Perrimon N. Resources for Functional Genomics Studies in Drosophila melanogaster. Genetics. 2014 May; 197(1):1-18.
    View in: PubMed
  5. Mohr SE. RNAi screening in Drosophila cells and in vivo. Methods. 2014 Jun 15; 68(1):82-8.
    View in: PubMed
  6. Vinayagam A, Zirin J, Roesel C, Hu Y, Yilmazel B, Samsonova AA, Neumüller RA, Mohr SE, Perrimon N. Integrating protein-protein interaction networks with phenotypes reveals signs of interactions. Nat Methods. 2014 Jan; 11(1):94-9.
    View in: PubMed
  7. Ren X, Sun J, Housden BE, Hu Y, Roesel C, Lin S, Liu LP, Yang Z, Mao D, Sun L, Wu Q, Ji JY, Xi J, Mohr SE, Xu J, Perrimon N, Ni JQ. Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):19012-7.
    View in: PubMed
  8. Hu Y, Sopko R, Foos M, Kelley C, Flockhart I, Ammeux N, Wang X, Perkins L, Perrimon N, Mohr SE. FlyPrimerBank: an online database for Drosophila melanogaster gene expression analysis and knockdown evaluation of RNAi reagents. G3 (Bethesda). 2013 Sep; 3(9):1607-16.
    View in: PubMed
  9. Hu Y, Roesel C, Flockhart I, Perkins L, Perrimon N, Mohr SE. UP-TORR: online tool for accurate and Up-to-Date annotation of RNAi Reagents. Genetics. 2013 Sep; 195(1):37-45.
    View in: PubMed
  10. Zhou R, Mohr S, Hannon GJ, Perrimon N. Inducing RNAi in Drosophila cells by transfection with dsRNA. Cold Spring Harb Protoc. 2013 May; 2013(5):461-3.
    View in: PubMed
  11. Bergwitz C, Wee MJ, Sinha S, Huang J, DeRobertis C, Mensah LB, Cohen J, Friedman A, Kulkarni M, Hu Y, Vinayagam A, Schnall-Levin M, Berger B, Perkins LA, Mohr SE, Perrimon N. Genetic determinants of phosphate response in Drosophila. PLoS One. 2013; 8(3):e56753.
    View in: PubMed
  12. Vinayagam A, Hu Y, Kulkarni M, Roesel C, Sopko R, Mohr SE, Perrimon N. Protein complex-based analysis framework for high-throughput data sets. Sci Signal. 2013 Feb 26; 6(264):rs5.
    View in: PubMed
  13. Neumüller RA, Wirtz-Peitz F, Lee S, Kwon Y, Buckner M, Hoskins RA, Venken KJ, Bellen HJ, Mohr SE, Perrimon N. Stringent analysis of gene function and protein-protein interactions using fluorescently tagged genes. Genetics. 2012 Mar; 190(3):931-40.
    View in: PubMed
  14. Flockhart IT, Booker M, Hu Y, McElvany B, Gilly Q, Mathey-Prevot B, Perrimon N, Mohr SE. FlyRNAi.org--the database of the Drosophila RNAi screening center: 2012 update. Nucleic Acids Res. 2012 Jan; 40(Database issue):D715-9.
    View in: PubMed
  15. Mohr SE, Perrimon N. RNAi screening: new approaches, understandings, and organisms. Wiley Interdiscip Rev RNA. 2012 Mar-Apr; 3(2):145-58.
    View in: PubMed
  16. Hu Y, Flockhart I, Vinayagam A, Bergwitz C, Berger B, Perrimon N, Mohr SE. An integrative approach to ortholog prediction for disease-focused and other functional studies. BMC Bioinformatics. 2011; 12:357.
    View in: PubMed
  17. Booker M, Samsonova AA, Kwon Y, Flockhart I, Mohr SE, Perrimon N. False negative rates in Drosophila cell-based RNAi screens: a case study. BMC Genomics. 2011; 12:50.
    View in: PubMed
  18. Markey AL, Mohr S, Day PJ. High-throughput droplet PCR. Methods. 2010 Apr; 50(4):277-81.
    View in: PubMed
  19. Mohr S, Bakal C, Perrimon N. Genomic screening with RNAi: results and challenges. Annu Rev Biochem. 2010; 79:37-64.
    View in: PubMed
  20. Cormier CY, Mohr SE, Zuo D, Hu Y, Rolfs A, Kramer J, Taycher E, Kelley F, Fiacco M, Turnbull G, LaBaer J. Protein Structure Initiative Material Repository: an open shared public resource of structural genomics plasmids for the biological community. Nucleic Acids Res. 2010 Jan; 38(Database issue):D743-9.
    View in: PubMed
  21. Myrick KV, Huet F, Mohr SE, Alvarez-García I, Lu JT, Smith MA, Crosby MA, Gelbart WM. Large-scale functional annotation and expanded implementations of the P{wHy} hybrid transposon in the Drosophila melanogaster genome. Genetics. 2009 Jul; 182(3):653-60.
    View in: PubMed
  22. Rolfs A, Montor WR, Yoon SS, Hu Y, Bhullar B, Kelley F, McCarron S, Jepson DA, Shen B, Taycher E, Mohr SE, Zuo D, Williamson J, Mekalanos J, Labaer J. Production and sequence validation of a complete full length ORF collection for the pathogenic bacterium Vibrio cholerae. Proc Natl Acad Sci U S A. 2008 Mar 18; 105(11):4364-9.
    View in: PubMed
  23. Murthy T, Rolfs A, Hu Y, Shi Z, Raphael J, Moreira D, Kelley F, McCarron S, Jepson D, Taycher E, Zuo D, Mohr SE, Fernandez M, Brizuela L, LaBaer J. A full-genomic sequence-verified protein-coding gene collection for Francisella tularensis. PLoS One. 2007; 2(6):e577.
    View in: PubMed
  24. Taycher E, Rolfs A, Hu Y, Zuo D, Mohr SE, Williamson J, Labaer J. A novel approach to sequence validating protein expression clones with automated decision making. BMC Bioinformatics. 2007; 8:198.
    View in: PubMed
  25. Hu Y, Rolfs A, Bhullar B, Murthy TV, Zhu C, Berger MF, Camargo AA, Kelley F, McCarron S, Jepson D, Richardson A, Raphael J, Moreira D, Taycher E, Zuo D, Mohr S, Kane MF, Williamson J, Simpson A, Bulyk ML, Harlow E, Marsischky G, Kolodner RD, LaBaer J. Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae. Genome Res. 2007 Apr; 17(4):536-43.
    View in: PubMed
  26. Zuo D, Mohr SE, Hu Y, Taycher E, Rolfs A, Kramer J, Williamson J, LaBaer J. PlasmID: a centralized repository for plasmid clone information and distribution. Nucleic Acids Res. 2007 Jan; 35(Database issue):D680-4.
    View in: PubMed
  27. Mohr SE, Gelbart WM. Using the P[wHy] hybrid transposable element to disrupt genes in region 54D-55B in Drosophila melanogaster. Genetics. 2002 Sep; 162(1):165-76.
    View in: PubMed
  28. Mohr SE, Boswell RE. Genetic analysis of Drosophila melanogaster polytene chromosome region 44D-45F: loci required for viability and fertility. Genetics. 2002 Apr; 160(4):1503-10.
    View in: PubMed
  29. Mohr SE, Dillon ST, Boswell RE. The RNA-binding protein Tsunagi interacts with Mago Nashi to establish polarity and localize oskar mRNA during Drosophila oogenesis. Genes Dev. 2001 Nov 1; 15(21):2886-99.
    View in: PubMed
  30. Mohr SE, Boswell RE. Zimp encodes a homologue of mouse Miz1 and PIAS3 and is an essential gene in Drosophila melanogaster. Gene. 1999 Mar 18; 229(1-2):109-16.
    View in: PubMed
  31. Newmark PA, Mohr SE, Gong L, Boswell RE. mago nashi mediates the posterior follicle cell-to-oocyte signal to organize axis formation in Drosophila. Development. 1997 Aug; 124(16):3197-207.
    View in: PubMed
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