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Last Name

profileDhvanit I Shah, Ph.D.

TitleInstructor in Medicine
InstitutionBrigham and Women's Hospital
AddressHarvard Institutes of Medicine
Him 622
77 Ave Louis Pasteur
Boston MA 02115
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Collapse Biography 
Collapse awards and honors
2003G. Achari Prize
2004O.D. Gulati Prize
2005O.D. Gulati Prize
2006 - 2008NRSA Fellowship
2008 - 2010Cooley's Anemia Foundation Research Fellowship
2010 - 2015NIDDK K01 Award
2013 - 2016ASH Junior Faculty Scholar Award
2013 - 2016NIDDK R03 Award
2016 - 2019St. Baldrick's Foundation Scholar

Collapse Research 
Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R01HL131645     (SHAH, DHVANIT INDRAVADAN)May 1, 2016 - Mar 31, 2021
Biomechanical Stimulation of Hemogenic Endothelial Cells to Develop Clinical-Grade Hematopoietic Stem Cells
Role: Principal Investigator

R03DK100672     (SHAH, DHVANIT INDRAVADAN)Dec 12, 2013 - Nov 30, 2015
Analysis of Mammalian Hematological Diseases in a Mouse Atpif1 Deficient Models
Role: Principal Investigator

K01DK085217     (SHAH, DHVANIT INDRAVADAN)Sep 15, 2010 - Aug 31, 2015
Zebrafish Genetics to Identify Genes Involved in Hematopoiesis
Role: Principal Investigator

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Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Dharampuriya PR, Scapin G, Wong C, John Wagner K, Cillis JL, Shah DI. Tracking the origin, development, and differentiation of hematopoietic stem cells. Curr Opin Cell Biol. 2017 Dec; 49:108-115. PMID: 29413969.
    View in: PubMed
  2. Mittal SK, Omoto M, Amouzegar A, Sahu A, Rezazadeh A, Katikireddy KR, Shah DI, Sahu SK, Chauhan SK. Restoration of Corneal Transparency by Mesenchymal Stem Cells. Stem Cell Reports. 2016 10 11; 7(4):583-590. PMID: 27693426.
    View in: PubMed
  3. Hagedorn EJ, Cillis JL, Curley CR, Patch TC, Li B, Blaser BW, Riquelme R, Zon LI, Shah DI. Generation of Parabiotic Zebrafish Embryos by Surgical Fusion of Developing Blastulae. J Vis Exp. 2016 Jun 11; (112). PMID: 27341538.
    View in: PubMed
  4. Hagedorn EJ, Cillis JL, Curley CR, Patch TC, Li B, Blaser BW, Riquelme R, Zon LI, Shah DI. Generation of parabiotic zebrafish embryos by surgical fusion of developing blastula. Journal of Visualized Experiments. J. Vis. Exp. 2015; (In Press).
  5. Anderson H, Patch TC, Reddy PN, Hagedorn EJ, Kim PG, Soltis KA, Chen MJ, Tamplin OJ, Frye M, MacLean GA, Hübner K, Bauer DE, Kanki JP, Vogin G, Huston NC, Nguyen M, Fujiwara Y, Paw BH, Vestweber D, Zon LI, Orkin SH, Daley GQ, Shah DI. Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression. Blood. 2015 Dec 24; 126(26):2811-20. PMID: 26385351; PMCID: PMC4692141 [Available on 12/24/16].
  6. Yien YY, Robledo RF, Schultz IJ, Takahashi-Makise N, Gwynn B, Bauer DE, Dass A, Yi G, Li L, Hildick-Smith GJ, Cooney JD, Pierce EL, Mohler K, Dailey TA, Miyata N, Kingsley PD, Garone C, Hattangadi SM, Huang H, Chen W, Keenan EM, Shah DI, Schlaeger TM, DiMauro S, Orkin SH, Cantor AB, Palis J, Koehler CM, Lodish HF, Kaplan J, Ward DM, Dailey HA, Phillips JD, Peters LL, Paw BH. TMEM14C is required for erythroid mitochondrial heme metabolism. J Clin Invest. 2014 Oct; 124(10):4294-304. PMID: 25157825; PMCID: PMC4191016.
  7. Hildick-Smith GJ, Cooney JD, Garone C, Kremer LS, Haack TB, Thon JN, Miyata N, Lieber DS, Calvo SE, Akman HO, Yien YY, Huston NC, Branco DS, Shah DI, Freedman ML, Koehler CM, Italiano JE, Merkenschlager A, Beblo S, Strom TM, Meitinger T, Freisinger P, Donati MA, Prokisch H, Mootha VK, DiMauro S, Paw BH. Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4. Am J Hum Genet. 2013 Nov 07; 93(5):906-14. PMID: 24119684; PMCID: PMC3824126.
  8. Chen C, Garcia-Santos D, Ishikawa Y, Seguin A, Li L, Fegan KH, Hildick-Smith GJ, Shah DI, Cooney JD, Chen W, King MJ, Yien YY, Schultz IJ, Anderson H, Dalton AJ, Freedman ML, Kingsley PD, Palis J, Hattangadi SM, Lodish HF, Ward DM, Kaplan J, Maeda T, Ponka P, Paw BH. Snx3 regulates recycling of the transferrin receptor and iron assimilation. Cell Metab. 2013 Mar 05; 17(3):343-52. PMID: 23416069; PMCID: PMC3595351.
  9. Shah DI, Takahashi-Makise N, Cooney JD, Li L, Schultz IJ, Pierce EL, Narla A, Seguin A, Hattangadi SM, Medlock AE, Langer NB, Dailey TA, Hurst SN, Faccenda D, Wiwczar JM, Heggers SK, Vogin G, Chen W, Chen C, Campagna DR, Brugnara C, Zhou Y, Ebert BL, Danial NN, Fleming MD, Ward DM, Campanella M, Dailey HA, Kaplan J, Paw BH. Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts. Nature. 2012 Nov 22; 491(7425):608-12. PMID: 23135403; PMCID: PMC3504625.
  10. Cooney JD, Hildick-Smith GJ, Shafizadeh E, McBride PF, Carroll KJ, Anderson H, Shaw GC, Tamplin OJ, Branco DS, Dalton AJ, Shah DI, Wong C, Gallagher PG, Zon LI, North TE, Paw BH. Teleost growth factor independence (gfi) genes differentially regulate successive waves of hematopoiesis. Dev Biol. 2013 Jan 15; 373(2):431-41. PMID: 22960038; PMCID: PMC3532562.
  11. Amigo JD, Ackermann GE, Cope JJ, Yu M, Cooney JD, Ma D, Langer NB, Shafizadeh E, Shaw GC, Horsely W, Trede NS, Davidson AJ, Barut BA, Zhou Y, Wojiski SA, Traver D, Moran TB, Kourkoulis G, Hsu K, Kanki JP, Shah DI, Lin HF, Handin RI, Cantor AB, Paw BH. The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish. Blood. 2009 Nov 19; 114(21):4654-63. PMID: 19729519; PMCID: PMC2780302.
  12. Kaur N, Kaur A, Bansal Y, Shah DI, Bansal G, Singh M. Design, synthesis, and evaluation of 5-sulfamoyl benzimidazole derivatives as novel angiotensin II receptor antagonists. Bioorg Med Chem. 2008 Dec 15; 16(24):10210-5. PMID: 19013821; PMCID: PMC3755122.
  13. Shah DI, Sharma M, Bansal Y, Bansal G, Singh M. Angiotensin II--AT1 receptor antagonists: design, synthesis and evaluation of substituted carboxamido benzimidazole derivatives. Eur J Med Chem. 2008 Sep; 43(9):1808-12. PMID: 18158200.
    View in: PubMed
  14. Shah DI, Singh M. Effect of demethylasterriquinone b1 in hypertension associated vascular endothelial dysfunction. Int J Cardiol. 2007 Sep 03; 120(3):317-24. PMID: 17240464.
    View in: PubMed
  15. Shah DI, Singh M. Possible role of exogenous cAMP to improve vascular endothelial dysfunction in hypertensive rats. Fundam Clin Pharmacol. 2006 Dec; 20(6):595-604. PMID: 17109653.
    View in: PubMed
  16. Dhvanit I Shah. Pharmacological Interventions to Improve Vascular Endothelium Dysfunction. 2006.
  17. Shah DI, Singh M. Effect of fasudil on macrovascular disorder-induced endothelial dysfunction. Can J Physiol Pharmacol. 2006 Aug-Sep; 84(8-9):835-45. PMID: 17111028.
    View in: PubMed
  18. Shah DI, Singh M. Possible role of Akt to improve vascular endothelial dysfunction in diabetic and hyperhomocysteinemic rats. Mol Cell Biochem. 2007 Jan; 295(1-2):65-74. PMID: 16841179.
    View in: PubMed
  19. Shah DI, Singh M. Activation of protein kinase A improves vascular endothelial dysfunction. Endothelium. 2006 Jul-Aug; 13(4):267-77. PMID: 16990183.
    View in: PubMed
  20. Shah DI, Kaur N, Bansal G, Singh M. Synthesis and pharmacological evaluation of novel angiotensin receptor-1 blockers. WTO Indian Patent Application No. 1311/DEL/2006. 2006.
  21. Shah DI, Singh M. Effect of bis(maltolato) oxovanadium on experimental vascular endothelial dysfunction. Naunyn Schmiedebergs Arch Pharmacol. 2006 Jun; 373(3):221-9. PMID: 16736159.
    View in: PubMed
  22. Shah DI, Santani DD, Goswami SS. A novel use of methylene blue as a pharmacological tool. J Pharmacol Toxicol Methods. 2006 Nov-Dec; 54(3):273-7. PMID: 16488629.
    View in: PubMed
  23. Shah DI, Singh M. Involvement of Rho-kinase in experimental vascular endothelial dysfunction. Mol Cell Biochem. 2006 Feb; 283(1-2):191-9. PMID: 16444602.
    View in: PubMed
  24. Shah DI, Singh M. Inhibition of protein tyrosin phosphatase improves vascular endothelial dysfunction. Vascul Pharmacol. 2006 Mar; 44(3):177-82. PMID: 16442349.
    View in: PubMed
  25. Santani DD, Jain SM, Shah DI. A pharmacometric model for peptic ulcer disease.WTO Indian Patent Application No. 1386/MUM/2004. 2004.
  26. Dhvanit I. Shah. Study of ulcerogenic potential of methylene blue and its mechanisms. 2003.
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