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Leo Am Kim, Ph.D., M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Quiroz YT, Sperling RA, Norton DJ, Baena A, Arboleda-Velasquez JF, Cosio D, Schultz A, Lapoint M, Guzman-Velez E, Miller JB, Kim LA, Chen K, Tariot PN, Lopera F, Reiman EM, Johnson KA. Association Between Amyloid and Tau Accumulation in Young Adults With Autosomal Dominant Alzheimer Disease. JAMA Neurol. 2018 May 01; 75(5):548-556. PMID: 29435558.
    View in: PubMed
  2. Carvalho LS, Xiao R, Wassmer SJ, Langsdorf A, Zinn E, Pacouret S, Shah S, Comander JI, Kim LA, Lim L, Vandenberghe LH. Synthetic Adeno-Associated Viral Vector Efficiently Targets Mouse and Nonhuman Primate Retina In Vivo. Hum Gene Ther. 2018 Jul; 29(7):771-784. PMID: 29325457.
    View in: PubMed
  3. Heiferman MJ, Rahmani S, Jampol LM, Nesper PL, Skondra D, Kim LA, Fawzi AA. ACUTE POSTERIOR MULTIFOCAL PLACOID PIGMENT EPITHELIOPATHY ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY. Retina. 2017 Nov; 37(11):2084-2094. PMID: 28151840.
    View in: PubMed
  4. Amarnani D, Machuca-Parra AI, Wong LL, Marko CK, Stefater JA, Stryjewski TP, Eliott D, Arboleda-Velasquez JF, Kim LA. Effect of Methotrexate on an In Vitro Patient-Derived Model of Proliferative Vitreoretinopathy. Invest Ophthalmol Vis Sci. 2017 08 01; 58(10):3940-3949. PMID: 28777835.
    View in: PubMed
  5. Machuca-Parra AI, Bigger-Allen AA, Sanchez AV, Boutabla A, Cardona-Vélez J, Amarnani D, Saint-Geniez M, Siebel CW, Kim LA, D'Amore PA, Arboleda-Velasquez JF. Therapeutic antibody targeting of Notch3 signaling prevents mural cell loss in CADASIL. J Exp Med. 2017 Aug 07; 214(8):2271-2282. PMID: 28698285.
    View in: PubMed
  6. Ung C, Sanchez AV, Shen L, Davoudi S, Ahmadi T, Navarro-Gomez D, Chen CJ, Hancock H, Penman A, Hoadley S, Consugar M, Restrepo C, Shah VA, Arboleda-Velasquez JF, Sobrin L, Gai X, Kim LA. Whole exome sequencing identification of novel candidate genes in patients with proliferative diabetic retinopathy. Vision Res. 2017 10; 139:168-176. PMID: 28431867.
    View in: PubMed
  7. Lam JD, Oh DJ, Wong LL, Amarnani D, Park-Windhol C, Sanchez AV, Cardona-Velez J, McGuone D, Stemmer-Rachamimov AO, Eliott D, Bielenberg DR, van Zyl T, Shen L, Gai X, D'Amore PA, Kim LA, Arboleda-Velasquez JF. Identification of RUNX1 as a Mediator of Aberrant Retinal Angiogenesis. Diabetes. 2017 07; 66(7):1950-1956. PMID: 28400392.
    View in: PubMed
  8. Yonekawa Y, Qian CX, Patel AV, Kim LA, Eliott D. Occult Perforating Globe Injury Caused by Intraocular Foreign Body. Ophthalmic Surg Lasers Imaging Retina. 2016 12 01; 47(12):1162-1163. PMID: 27977843.
    View in: PubMed
  9. Stefater JA, Eliott D, Kim LA. Drainage and analysis of suprachoroidal fluid in a patient with acute systemic lupus erythematous. Am J Ophthalmol Case Rep. 2017 Apr; 5:29-32. PMID: 29503942.
    View in: PubMed
  10. Papakostas TD, Jakobiec FA, Stagner AM, Eliott D, Kim LA. Small-Caliber Retinal Vasculitis Associated With Giant Cell Arteritis: A New Finding. Ophthalmic Surg Lasers Imaging Retina. 2016 11 01; 47(11):1054-1056. PMID: 27842201.
    View in: PubMed
  11. Finn AP, Eliott D, Kim LA, Husain D, Wu DM, Young LH, Kim IK, Andreoli C, Skondra D, Vavvas DG, Miller JB. Characteristics and Outcomes of Simultaneous Bilateral Rhegmatogenous Retinal Detachments. Ophthalmic Surg Lasers Imaging Retina. 2016 09 01; 47(9):840-5. PMID: 27631480.
    View in: PubMed
  12. Pennock S, Kim LA, Kazlauskas A. Vascular Endothelial Cell Growth Factor A Acts via Platelet-Derived Growth Factor Receptor a To Promote Viability of Cells Enduring Hypoxia. Mol Cell Biol. 2016 09 15; 36(18):2314-27. PMID: 27325673.
    View in: PubMed
  13. Wong LL, Lee NG, Amarnani D, Choi CJ, Bielenberg DR, Freitag SK, D'Amore PA, Kim LA. Orbital Angiogenesis and Lymphangiogenesis in Thyroid Eye Disease: An Analysis of Vascular Growth Factors with Clinical Correlation. Ophthalmology. 2016 09; 123(9):2028-36. PMID: 27423310.
    View in: PubMed
  14. Miller JB, Yonekawa Y, Eliott D, Kim IK, Kim LA, Loewenstein JI, Sobrin L, Young LH, Mukai S, Vavvas DG. Long-term Follow-up and Outcomes in Traumatic Macular Holes. Am J Ophthalmol. 2016 06; 166:206-207. PMID: 27084591.
    View in: PubMed
  15. Miller JB, Yonekawa Y, Eliott D, Kim IK, Kim LA, Loewenstein JI, Sobrin L, Young LH, Mukai S, Vavvas DG. Long-term Follow-up and Outcomes in Traumatic Macular Holes. Am J Ophthalmol. 2015 Dec; 160(6):1255-1258.e1. PMID: 26393438.
    View in: PubMed
  16. Lim LS, Ng WY, Mathur R, Wong D, Wong EY, Yeo I, Cheung CM, Lee SY, Wong TY, Papakostas TD, Kim LA. Conversion to aflibercept for diabetic macular edema unresponsive to ranibizumab or bevacizumab. Clin Ophthalmol. 2015; 9:1715-8. PMID: 26396494; PMCID: PMC4577250.
  17. Sweigard JH, Matsumoto H, Smith KE, Kim LA, Paschalis EI, Okonuki Y, Castillejos A, Kataoka K, Hasegawa E, Yanai R, Husain D, Lambris JD, Vavvas D, Miller JW, Connor KM. Inhibition of the alternative complement pathway preserves photoreceptors after retinal injury. Sci Transl Med. 2015 Jul 22; 7(297):297ra116. PMID: 26203084; PMCID: PMC4779952.
  18. Kim LA, Wong LL, Amarnani DS, Bigger-Allen AA, Hu Y, Marko CK, Eliott D, Shah VA, McGuone D, Stemmer-Rachamimov AO, Gai X, D'Amore PA, Arboleda-Velasquez JF. Characterization of cells from patient-derived fibrovascular membranes in proliferative diabetic retinopathy. Mol Vis. 2015; 21:673-87. PMID: 26120272; PMCID: PMC4462955.
  19. Srinivasan PP, Kim LA, Mettu PS, Cousins SW, Comer GM, Izatt JA, Farsiu S. Fully automated detection of diabetic macular edema and dry age-related macular degeneration from optical coherence tomography images. Biomed Opt Express. 2014 Oct 01; 5(10):3568-77. PMID: 25360373; PMCID: PMC4206325.
  20. Valdez CN, Arboleda-Velasquez JF, Amarnani DS, Kim LA, D'Amore PA. Retinal microangiopathy in a mouse model of inducible mural cell loss. Am J Pathol. 2014 Oct; 184(10):2618-26. PMID: 25092275; PMCID: PMC4715212.
  21. Kim LA, Amarnani D, Gnanaguru G, Tseng WA, Vavvas DG, D'Amore PA. Tamoxifen toxicity in cultured retinal pigment epithelial cells is mediated by concurrent regulated cell death mechanisms. Invest Ophthalmol Vis Sci. 2014 Jul 03; 55(8):4747-58. PMID: 24994868; PMCID: PMC4122018.
  22. Miller JB, Kim LA, Wu DM, Vavvas DG, Eliott D, Husain D. Ocriplasmin for treatment of stage 2 macular holes: early clinical results. Ophthalmic Surg Lasers Imaging Retina. 2014 Jul-Aug; 45(4):293-7. PMID: 25037011; PMCID: PMC4342757.
  23. Lee NG, Kim LA, Freitag SK. The role of genetics in the pathogenesis of periocular cutaneous neoplasms: implications for targeted therapy. Semin Ophthalmol. 2013 Sep-Nov; 28(5-6):267-74. PMID: 24138034; PMCID: PMC4342750.
  24. Bagchi M, Kim LA, Boucher J, Walshe TE, Kahn CR, D'Amore PA. Vascular endothelial growth factor is important for brown adipose tissue development and maintenance. FASEB J. 2013 Aug; 27(8):3257-71. PMID: 23682123; PMCID: PMC3714576.
  25. Kim LH, Zhang M, Howell RW, Yue NJ, Khan AJ. Technical note: contrast solution density and cross section errors in inhomogeneity-corrected dose calculation for breast balloon brachytherapy. Med Phys. 2013 Jan; 40(1):011703. PMID: 23298073.
    View in: PubMed
  26. Huang AS, Kim LA, Fawzi AA. Clinical characteristics of a large choroideremia pedigree carrying a novel CHM mutation. Arch Ophthalmol. 2012 Sep; 130(9):1184-9. PMID: 22965595; PMCID: PMC3984921.
  27. Sohn EH, He S, Kim LA, Salehi-Had H, Javaheri M, Spee C, Dustin L, Hinton DR, Eliott D. Angiofibrotic response to vascular endothelial growth factor inhibition in diabetic retinal detachment: report no. 1. Arch Ophthalmol. 2012 Sep; 130(9):1127-34. PMID: 22965588; PMCID: PMC3984910.
  28. Kim LA, D'Amore PA. A brief history of anti-VEGF for the treatment of ocular angiogenesis. Am J Pathol. 2012 Aug; 181(2):376-9. PMID: 22749677.
    View in: PubMed
  29. Kim LH, Goyal S, Haffty BG, Taunk NK, Yue NJ. Using respiratory motion to guide planning target volume margins for external beam partial breast irradiation. Int J Radiat Oncol Biol Phys. 2012 Mar 15; 82(4):1303-6. PMID: 22385703.
    View in: PubMed
  30. Ghilezan M, Martinez A, Gustason G, Krauss D, Antonucci JV, Chen P, Fontanesi J, Wallace M, Ye H, Casey A, Sebastian E, Kim L, Limbacher A. High-dose-rate brachytherapy as monotherapy delivered in two fractions within one day for favorable/intermediate-risk prostate cancer: preliminary toxicity data. Int J Radiat Oncol Biol Phys. 2012 Jul 01; 83(3):927-32. PMID: 22197086.
    View in: PubMed
  31. Thomas BB, Shi D, Khine K, Kim LA, Sadda SR. Modulatory influence of stimulus parameters on optokinetic head-tracking response. Neurosci Lett. 2010 Jul 26; 479(2):92-6. PMID: 20488227; PMCID: PMC3995157.
  32. Kim LA, Khurana RN, Parikh JG, Rao NA. Melanin-laden macrophages in the CSF to diagnose Vogt-Koyanagi-Harada simulating ocular syphilis. Ocul Immunol Inflamm. 2008 Jan-Feb; 16(1):59-61. PMID: 18379946.
    View in: PubMed
  33. Kim LA, Furst J, Gutierrez D, Butler MH, Xu S, Goldstein SA, Grigorieff N. Three-dimensional structure of I(to); Kv4.2-KChIP2 ion channels by electron microscopy at 21 Angstrom resolution. Neuron. 2004 Feb 19; 41(4):513-9. PMID: 14980201.
    View in: PubMed
  34. Kim LA, Furst J, Butler MH, Xu S, Grigorieff N, Goldstein SA. Ito channels are octomeric complexes with four subunits of each Kv4.2 and K+ channel-interacting protein 2. J Biol Chem. 2004 Feb 13; 279(7):5549-54. PMID: 14623880.
    View in: PubMed
  35. Chen H, Kim LA, Rajan S, Xu S, Goldstein SA. Charybdotoxin binding in the I(Ks) pore demonstrates two MinK subunits in each channel complex. Neuron. 2003 Sep 25; 40(1):15-23. PMID: 14527430.
    View in: PubMed
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.