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Eric Lieberman Greer, Ph.D.

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Biography
2006 - 2009
National Science Foundation (NSF) Graduate Research Fellowship (GRF)
2006
Selected speaker - Molecular Genetics of Aging - scientific meeting
2008
Selected speaker - Molecular Genetics of Aging - scientific meeting
2010
Life Science Research Foundation Fellowship Finalist (declined)
2010
Runner up for the Aging Cell Best paper prize for 2009
2011 - 2013
Helen Hay Whitney Fellowship
2011
Selected speaker - Epigenetics and the Inheritance of Acquired States
2011
Selected speaker - Chromatin: Structure & Function 2011
2012
Invited Age UK speaker - Ageing and Basic Bioscience Conference
2012
Invited Keynote speaker - Epigenetics 2012 - 4th Australian Scientific Conference
2012
Invited speaker - Transcriptional Regulation During Cell Growth, Dif, and Dev.
2013
Invited talk NIH NCI CEICBG Seminar Series
2013 - 2018
NIH Pathway to Independence Award (K99/R00)
2014
Selected speaker - Chromatin Mechanisms and Cell Physiology
2014
Selected speaker - Epigenetic Programming and Inheritance
2015
Invited speaker - The XXIII North American Testis Workshop
2015
Invited speaker - Non-coding RNA: New Mechanisms and Approaches
2015
Invited speaker - Chromatin Changes in Differentiation and Malignancy
2015
Invited speaker - Epigenetics Obesity and Metabolism

Overview
I am an Assistant Professor at Boston Children's Hospital and Harvard Medical School (http://thegreerlab.com). I did my post-doctoral research in Dr. Yang Shi's laboratory (http://www.shilab.info/ShiLab/Welcome.html) at Boston Children's Hospital and Harvard Medical School. I did my graduate work in the lab of Dr. Anne Brunet (http://www.stanford.edu/group/brunet/) at Stanford University. I am interested in identifying how epigenetic information is transmitted from parents to their descendants in a non-Mendelian manner.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21HG010066 (GREER, ERIC LIEBERMAN) Sep 1, 2018 - Aug 31, 2020
    NIH/NHGRI
    Base-resolution sequencing of 6mA in eukaryotic DNA
    Role: Principal Investigator
  2. DP2AG055947 (GREER, ERIC LIEBERMAN) Sep 30, 2016 - Jun 30, 2021
    NIH/NIA
    Characterization of DNA N6-methyl adenine and its role in epigenetic memory
    Role: Principal Investigator
  3. R00AG043550 (GREER, ERIC LIEBERMAN) Jul 15, 2015 - Mar 31, 2018
    NIH/NIA
    Identifying the molecular mechanisms of transgenerational epigenetic inheritance
    Role: Principal Investigator
  4. K99AG043550 (GREER, ERIC L.) Sep 1, 2013 - May 31, 2015
    NIH/NIA
    Identifying the molecular mechanisms of transgenerational epigenetic inheritance
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Boulias K, Lieberman J, Greer EL. An Epigenetic Clock Measures Accelerated Aging in Treated HIV Infection. Mol Cell. 2016 04 21; 62(2):153-155. PMID: 27105110.
    Citations: 2     Fields:    Translation:HumansCells
  2. O'Brown ZK, Greer EL. N6-Methyladenine: A Conserved and Dynamic DNA Mark. Adv Exp Med Biol. 2016; 945:213-246. PMID: 27826841.
    Citations: 3     Fields:    Translation:AnimalsCells
  3. Greer EL, Becker B, Latza C, Antebi A, Shi Y. Mutation of C. elegans demethylase spr-5 extends transgenerational longevity. Cell Res. 2016 Feb; 26(2):229-38. PMID: 26691751; PMCID: PMC4746603.
    Citations: 6     Fields:    Translation:AnimalsCells
  4. Luo GZ, Blanco MA, Greer EL, He C, Shi Y. DNA N(6)-methyladenine: a new epigenetic mark in eukaryotes? Nat Rev Mol Cell Biol. 2015 Dec; 16(12):705-10. PMID: 26507168; PMCID: PMC4763336.
    Citations: 22     Fields:    Translation:AnimalsCells
  5. Greer EL, Blanco MA, Gu L, Sendinc E, Liu J, Aristizábal-Corrales D, Hsu CH, Aravind L, He C, Shi Y. DNA Methylation on N6-Adenine in C. elegans. Cell. 2015 May 07; 161(4):868-78. PMID: 25936839; PMCID: PMC4427530.
    Citations: 88     Fields:    Translation:AnimalsCells
  6. Greer EL, Beese-Sims SE, Brookes E, Spadafora R, Zhu Y, Rothbart SB, Aristizábal-Corrales D, Chen S, Badeaux AI, Jin Q, Wang W, Strahl BD, Colaiácovo MP, Shi Y. A histone methylation network regulates transgenerational epigenetic memory in C. elegans. Cell Rep. 2014 Apr 10; 7(1):113-26. PMID: 24685137; PMCID: PMC4012616.
    Citations: 32     Fields:    Translation:AnimalsCells
  7. Greer EL, Shi Y. What's the Mtrr with your grandparents? Cell Metab. 2013 Oct 01; 18(4):457-9. PMID: 24093670; PMCID: PMC3947785.
    Citations:    Fields:    Translation:Animals
  8. Greer EL, Shi Y. Histone methylation: a dynamic mark in health, disease and inheritance. Nat Rev Genet. 2012 Apr 03; 13(5):343-57. PMID: 22473383; PMCID: PMC4073795.
    Citations: 445     Fields:    Translation:HumansAnimalsCells
  9. Greer EL, Maures TJ, Ucar D, Hauswirth AG, Mancini E, Lim JP, Benayoun BA, Shi Y, Brunet A. Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans. Nature. 2011 Oct 19; 479(7373):365-71. PMID: 22012258; PMCID: PMC3368121.
    Citations: 175     Fields:    Translation:AnimalsCells
  10. Maures TJ, Greer EL, Hauswirth AG, Brunet A. The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner. Aging Cell. 2011 Dec; 10(6):980-90. PMID: 21834846; PMCID: PMC3215905.
    Citations: 71     Fields:    Translation:AnimalsCells
  11. Greer EL, Maures TJ, Hauswirth AG, Green EM, Leeman DS, Maro GS, Han S, Banko MR, Gozani O, Brunet A. Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans. Nature. 2010 Jul 15; 466(7304):383-7. PMID: 20555324; PMCID: PMC3075006.
    Citations: 138     Fields:    Translation:AnimalsCells
  12. Greer EL, Banko MR, Brunet A. AMP-activated protein kinase and FoxO transcription factors in dietary restriction-induced longevity. Ann N Y Acad Sci. 2009 Jul; 1170:688-92. PMID: 19686213; PMCID: PMC2814416.
    Citations: 38     Fields:    Translation:AnimalsCells
  13. Greer EL, Brunet A. Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans. Aging Cell. 2009 Apr; 8(2):113-27. PMID: 19239417; PMCID: PMC2680339.
    Citations: 193     Fields:    Translation:AnimalsCells
  14. Greer EL, Brunet A. Signaling networks in aging. J Cell Sci. 2008 Feb 15; 121(Pt 4):407-12. PMID: 18256383.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  15. Greer EL, Brunet A. FOXO transcription factors in ageing and cancer. Acta Physiol (Oxf). 2008 Jan; 192(1):19-28. PMID: 18171426.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  16. Greer EL, Dowlatshahi D, Banko MR, Villen J, Hoang K, Blanchard D, Gygi SP, Brunet A. An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans. Curr Biol. 2007 Oct 09; 17(19):1646-56. PMID: 17900900; PMCID: PMC2185793.
    Citations: 254     Fields:    Translation:AnimalsCells
  17. Greer EL, Oskoui PR, Banko MR, Maniar JM, Gygi MP, Gygi SP, Brunet A. The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor. J Biol Chem. 2007 Oct 12; 282(41):30107-19. PMID: 17711846.
    Citations: 250     Fields:    Translation:HumansAnimalsCells
  18. Pondarré C, Antiochos BB, Campagna DR, Clarke SL, Greer EL, Deck KM, McDonald A, Han AP, Medlock A, Kutok JL, Anderson SA, Eisenstein RS, Fleming MD. The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis. Hum Mol Genet. 2006 Mar 15; 15(6):953-64. PMID: 16467350.
    Citations: 58     Fields:    Translation:AnimalsCells
  19. Greer EL, Brunet A. FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene. 2005 Nov 14; 24(50):7410-25. PMID: 16288288.
    Citations: 403     Fields:    Translation:HumansAnimalsCells
  20. Ohgami RS, Campagna DR, Greer EL, Antiochos B, McDonald A, Chen J, Sharp JJ, Fujiwara Y, Barker JE, Fleming MD. Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Nat Genet. 2005 Nov; 37(11):1264-9. PMID: 16227996; PMCID: PMC2156108.
    Citations: 139     Fields:    Translation:AnimalsCells
  21. Gunshin H, Starr CN, Direnzo C, Fleming MD, Jin J, Greer EL, Sellers VM, Galica SM, Andrews NC. Cybrd1 (duodenal cytochrome b) is not necessary for dietary iron absorption in mice. Blood. 2005 Oct 15; 106(8):2879-83. PMID: 15961514; PMCID: PMC1895297.
    Citations: 36     Fields:    Translation:AnimalsCells
  22. Beresford PJ, Zhang D, Oh DY, Fan Z, Greer EL, Russo ML, Jaju M, Lieberman J. Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks. J Biol Chem. 2001 Nov 16; 276(46):43285-93. PMID: 11555662.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.