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Reiko Nishihara, Ph.D.

TitleInstructor in Medicine
InstitutionDana-Farber Cancer Institute
DepartmentMedicine
AddressDana-Farber Cancer Institute
450 Brookline Ave - JF208E
44 Binney St
Boston MA 02115
Phone617/384-8929
Fax617/582-8558

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Giannakis M, Hodis E, Jasmine Mu X, Yamauchi M, Rosenbluh J, Cibulskis K, Saksena G, Lawrence MS, Qian ZR, Nishihara R, Van Allen EM, Hahn WC, Gabriel SB, Lander ES, Getz G, Ogino S, Fuchs CS, Garraway LA. RNF43 is frequently mutated in colorectal and endometrial cancers. Nat Genet. 2014 Dec; 46(12):1264-6.
    View in: PubMed
  2. Nishihara R, Wang M, Qian ZR, Baba Y, Yamauchi M, Mima K, Sukawa Y, Kim SA, Inamura K, Zhang X, Wu K, Giovannucci EL, Chan AT, Fuchs CS, Ogino S, Schernhammer ES. Alcohol, one-carbon nutrient intake, and risk of colorectal cancer according to tumor methylation level of IGF2 differentially methylated region. Am J Clin Nutr. 2014 Dec; 100(6):1479-88.
    View in: PubMed
  3. Inamura K, Yamauchi M, Nishihara R, Lochhead P, Qian ZR, Kuchiba A, Kim SA, Mima K, Sukawa Y, Jung S, Zhang X, Wu K, Cho E, Chan AT, Meyerhardt JA, Harris CC, Fuchs CS, Ogino S. Tumor LINE-1 Methylation Level and Microsatellite Instability in Relation to Colorectal Cancer Prognosis. J Natl Cancer Inst. 2014 Sep; 106(9).
    View in: PubMed
  4. Li T, Liao X, Lochhead P, Morikawa T, Yamauchi M, Nishihara R, Inamura K, Kim SA, Mima K, Sukawa Y, Kuchiba A, Imamura Y, Baba Y, Shima K, Meyerhardt JA, Chan AT, Fuchs CS, Ogino S, Qian ZR. SMO Expression in Colorectal Cancer: Associations with Clinical, Pathological, and Molecular Features. Ann Surg Oncol. 2014 Dec; 21(13):4164-73.
    View in: PubMed
  5. Lochhead P, Chan AT, Giovannucci E, Fuchs CS, Wu K, Nishihara R, O'Brien M, Ogino S. Progress and opportunities in molecular pathological epidemiology of colorectal premalignant lesions. Am J Gastroenterol. 2014 Aug; 109(8):1205-14.
    View in: PubMed
  6. Jung S, Qian ZR, Yamauchi M, Bertrand KA, Fitzgerald KC, Inamura K, Kim SA, Mima K, Sukawa Y, Zhang X, Wang M, Smith-Warner SA, Wu K, Fuchs CS, Chan AT, Giovannucci EL, Ng K, Cho E, Ogino S, Nishihara R. Predicted 25(OH)D Score and Colorectal Cancer Risk According to Vitamin D Receptor Expression. Cancer Epidemiol Biomarkers Prev. 2014 Aug; 23(8):1628-37.
    View in: PubMed
  7. Imamura Y, Lochhead P, Yamauchi M, Kuchiba A, Qian ZR, Liao X, Nishihara R, Jung S, Wu K, Nosho K, Wang YE, Peng S, Bass AJ, Haigis KM, Meyerhardt JA, Chan AT, Fuchs CS, Ogino S. Analyses of clinicopathological, molecular, and prognostic associations of KRAS codon 61 and codon 146 mutations in colorectal cancer: cohort study and literature review. Mol Cancer. 2014; 13(1):135.
    View in: PubMed
  8. Nishihara R, Ogino S, Chan AT. Reply. Gastroenterology. 2014 Jul; 147(1):246-7.
    View in: PubMed
  9. Fink SP, Yamauchi M, Nishihara R, Jung S, Kuchiba A, Wu K, Cho E, Giovannucci E, Fuchs CS, Ogino S, Markowitz SD, Chan AT. Aspirin and the Risk of Colorectal Cancer in Relation to the Expression of 15-Hydroxyprostaglandin Dehydrogenase (HPGD). Sci Transl Med. 2014 Apr 23; 6(233):233re2.
    View in: PubMed
  10. Hayashi C, Mikami H, Nishihara R, Maeda C, Hayakawa K. The relationship between twin language, twins' close ties, and social competence. Twin Res Hum Genet. 2014 Feb; 17(1):27-37.
    View in: PubMed
  11. Nishihara R, Ogino S, Chan AT. Colorectal-cancer incidence and mortality after screening. N Engl J Med. 2013 Dec 12; 369(24):2355.
    View in: PubMed
  12. Nishihara R, Wu K, Lochhead P, Morikawa T, Liao X, Qian ZR, Inamura K, Kim SA, Kuchiba A, Yamauchi M, Imamura Y, Willett WC, Rosner BA, Fuchs CS, Giovannucci E, Ogino S, Chan AT. Long-term colorectal-cancer incidence and mortality after lower endoscopy. N Engl J Med. 2013 Sep 19; 369(12):1095-105.
    View in: PubMed
  13. Lochhead P, Kuchiba A, Imamura Y, Liao X, Yamauchi M, Nishihara R, Qian ZR, Morikawa T, Shen J, Meyerhardt JA, Fuchs CS, Ogino S. Microsatellite instability and BRAF mutation testing in colorectal cancer prognostication. J Natl Cancer Inst. 2013 Aug 7; 105(15):1151-6.
    View in: PubMed
  14. Nishihara R, Lochhead P, Kuchiba A, Jung S, Yamauchi M, Liao X, Imamura Y, Qian ZR, Morikawa T, Wang M, Spiegelman D, Cho E, Giovannucci E, Fuchs CS, Chan AT, Ogino S. Aspirin use and risk of colorectal cancer according to BRAF mutation status. JAMA. 2013 Jun 26; 309(24):2563-71.
    View in: PubMed
  15. Nishihara R, Morikawa T, Kuchiba A, Lochhead P, Yamauchi M, Liao X, Imamura Y, Nosho K, Shima K, Kawachi I, Qian ZR, Fuchs CS, Chan AT, Giovannucci E, Ogino S. A prospective study of duration of smoking cessation and colorectal cancer risk by epigenetics-related tumor classification. Am J Epidemiol. 2013 Jul 1; 178(1):84-100.
    View in: PubMed
  16. Yamauchi M, Lochhead P, Imamura Y, Kuchiba A, Liao X, Qian ZR, Nishihara R, Morikawa T, Shima K, Wu K, Giovannucci E, Meyerhardt JA, Fuchs CS, Chan AT, Ogino S. Physical activity, tumor PTGS2 expression, and survival in patients with colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2013 Jun; 22(6):1142-52.
    View in: PubMed
  17. Morikawa T, Kuchiba A, Lochhead P, Nishihara R, Yamauchi M, Imamura Y, Liao X, Qian ZR, Ng K, Chan AT, Meyerhardt JA, Giovannucci E, Fuchs CS, Ogino S. Prospective analysis of body mass index, physical activity, and colorectal cancer risk associated with ß-catenin (CTNNB1) status. Cancer Res. 2013 Mar 1; 73(5):1600-10.
    View in: PubMed
  18. Ogino S, Lochhead P, Chan AT, Nishihara R, Cho E, Wolpin BM, Meyerhardt JA, Meissner A, Schernhammer ES, Fuchs CS, Giovannucci E. Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease. Mod Pathol. 2013 Apr; 26(4):465-84.
    View in: PubMed
  19. Ogino S, Nishihara R, Lochhead P, Imamura Y, Kuchiba A, Morikawa T, Yamauchi M, Liao X, Qian ZR, Sun R, Sato K, Kirkner GJ, Wang M, Spiegelman D, Meyerhardt JA, Schernhammer ES, Chan AT, Giovannucci E, Fuchs CS. Prospective study of family history and colorectal cancer risk by tumor LINE-1 methylation level. J Natl Cancer Inst. 2013 Jan 16; 105(2):130-40.
    View in: PubMed
  20. Liao X, Lochhead P, Nishihara R, Morikawa T, Kuchiba A, Yamauchi M, Imamura Y, Qian ZR, Baba Y, Shima K, Sun R, Nosho K, Meyerhardt JA, Giovannucci E, Fuchs CS, Chan AT, Ogino S. Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival. N Engl J Med. 2012 Oct 25; 367(17):1596-606.
    View in: PubMed
  21. Lochhead P, Imamura Y, Morikawa T, Kuchiba A, Yamauchi M, Liao X, Qian ZR, Nishihara R, Wu K, Meyerhardt JA, Fuchs CS, Ogino S. Insulin-like growth factor 2 messenger RNA binding protein 3 (IGF2BP3) is a marker of unfavourable prognosis in colorectal cancer. Eur J Cancer. 2012 Dec; 48(18):3405-13.
    View in: PubMed
  22. Imamura Y, Morikawa T, Liao X, Lochhead P, Kuchiba A, Yamauchi M, Qian ZR, Nishihara R, Meyerhardt JA, Haigis KM, Fuchs CS, Ogino S. Specific mutations in KRAS codons 12 and 13, and patient prognosis in 1075 BRAF wild-type colorectal cancers. Clin Cancer Res. 2012 Sep 1; 18(17):4753-63.
    View in: PubMed
  23. Yamauchi M, Morikawa T, Kuchiba A, Imamura Y, Qian ZR, Nishihara R, Liao X, Waldron L, Hoshida Y, Huttenhower C, Chan AT, Giovannucci E, Fuchs C, Ogino S. Assessment of colorectal cancer molecular features along bowel subsites challenges the conception of distinct dichotomy of proximal versus distal colorectum. Gut. 2012 Jun; 61(6):847-54.
    View in: PubMed
  24. Liao X, Morikawa T, Lochhead P, Imamura Y, Kuchiba A, Yamauchi M, Nosho K, Qian ZR, Nishihara R, Meyerhardt JA, Fuchs CS, Ogino S. Prognostic role of PIK3CA mutation in colorectal cancer: cohort study and literature review. Clin Cancer Res. 2012 Apr 15; 18(8):2257-68.
    View in: PubMed
  25. Morikawa T, Kuchiba A, Qian ZR, Mino-Kenudson M, Hornick JL, Yamauchi M, Imamura Y, Liao X, Nishihara R, Meyerhardt JA, Fuchs CS, Ogino S. Prognostic significance and molecular associations of tumor growth pattern in colorectal cancer. Ann Surg Oncol. 2012 Jun; 19(6):1944-53.
    View in: PubMed
  26. Morikawa T, Kuchiba A, Liao X, Imamura Y, Yamauchi M, Qian ZR, Nishihara R, Sato K, Meyerhardt JA, Fuchs CS, Ogino S. Tumor TP53 expression status, body mass index and prognosis in colorectal cancer. Int J Cancer. 2012 Sep 1; 131(5):1169-78.
    View in: PubMed
  27. Nishihara R, Inui F, Kato K, Tomizawa R, Hayakawa K. Genetic contribution to the relationship between social role function and depressive symptoms in Japanese elderly twins: a twin study. Psychogeriatrics. 2011 Mar; 11(1):19-27.
    View in: PubMed
  28. Arias JF, Nishihara R, Bala M, Ikuta K. High systemic levels of interleukin-10, interleukin-22 and C-reactive protein in Indian patients are associated with low in vitro replication of HIV-1 subtype C viruses. Retrovirology. 2010; 7:15.
    View in: PubMed
  29. Cai YP, Hayakawa K, Nishihara R, Kato K. Heritability of serum apolipoprotein concentrations in middle-aged Japanese twins. J Epidemiol. 2009; 19(5):260-5.
    View in: PubMed
  30. Hayashi C, Hayakawa K, Maeda C, Nishihara R, Onoi M. [Social development of twins: the need for intervention to avoid adverse effects of twin language]. Nihon Koshu Eisei Zasshi. 2008 Oct; 55(10):701-15.
    View in: PubMed
  31. Hayakawa K, Kato K, Onoi M, Hayashi C, Yang-Ping C, Kanamori M, Doi S, Kikuchi H, Nishihara R, Kadota K. The Japanese Study of Adult Twins Reared Apart and Growing Old Separately. Twin Res Hum Genet. 2006 Dec; 9(6):806-7.
    View in: PubMed
  32. Hayakawa K, Kato K, Onoi M, Yang-Ping C, Kanamori M, Doi S, Hayashi C, Kikuchi H, Nishihara R, Kadota K. The Osaka University Aged Twin Registry: epigenetics and identical twins discordant for aging-dependent diseases. Twin Res Hum Genet. 2006 Dec; 9(6):808-10.
    View in: PubMed
  33. Nishihara R, Hattori R, Kobayashi Y, Hayakawa K. [Parenting anxiety and childhood development of twins as compared to singletons]. Nihon Koshu Eisei Zasshi. 2006 Nov; 53(11):831-41.
    View in: PubMed
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