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profileSriram Sankararaman, Ph.D.

TitleResearch Associate in Genetics
InstitutionHarvard Medical School
DepartmentGenetics
AddressHarvard Medical School
Dept of Genetics
77 Avenue Louis Pasteur
Boston MA 02115
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Moorjani P, Sankararaman S, Fu Q, Przeworski M, Patterson N, Reich D. A genetic method for dating ancient genomes provides a direct estimate of human generation interval in the last 45,000 years. Proc Natl Acad Sci U S A. 2016 May 17; 113(20):5652-7. PMID: 27140627.
    View in: PubMed
  2. Sankararaman S, Mallick S, Patterson N, Reich D. The Combined Landscape of Denisovan and Neanderthal Ancestry in Present-Day Humans. Curr Biol. 2016 May 9; 26(9):1241-7. PMID: 27032491.
    View in: PubMed
  3. Lipson M, Loh PR, Sankararaman S, Patterson N, Berger B, Reich D. Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes. PLoS Genet. 2015 Nov; 11(11):e1005550. PMID: 26562831; PMCID: PMC4642934.
  4. Palamara PF, Francioli LC, Wilton PR, Genovese G, Gusev A, Finucane HK, Sankararaman S, Sunyaev SR, de Bakker PI, Wakeley J, Pe'er I, Price AL. Leveraging Distant Relatedness to Quantify Human Mutation and Gene-Conversion Rates. Am J Hum Genet. 2015 Dec 3; 97(6):775-89. PMID: 26581902.
    View in: PubMed
  5. Zou JY, Park DS, Burchard EG, Torgerson DG, Pino-Yanes M, Song YS, Sankararaman S, Halperin E, Zaitlen N. Genetic and socioeconomic study of mate choice in Latinos reveals novel assortment patterns. Proc Natl Acad Sci U S A. 2015 Nov 3; 112(44):13621-6. PMID: 26483472; PMCID: PMC4640764 [Available on 05/03/16].
  6. Zou JY, Halperin E, Burchard E, Sankararaman S. Inferring parental genomic ancestries using pooled semi-Markov processes. Bioinformatics. 2015 Jun 15; 31(12):i190-6. PMID: 26072482.
    View in: PubMed
  7. Racimo F, Sankararaman S, Nielsen R, Huerta-Sánchez E. Evidence for archaic adaptive introgression in humans. Nat Rev Genet. 2015 Jun; 16(6):359-71. PMID: 25963373; PMCID: PMC4478293.
  8. Zaitlen N, Pasaniuc B, Sankararaman S, Bhatia G, Zhang J, Gusev A, Young T, Tandon A, Pollack S, Vilhjálmsson BJ, Assimes TL, Berndt SI, Blot WJ, Chanock S, Franceschini N, Goodman PG, He J, Hennis AJ, Hsing A, Ingles SA, Isaacs W, Kittles RA, Klein EA, Lange LA, Nemesure B, Patterson N, Reich D, Rybicki BA, Stanford JL, Stevens VL, Strom SS, Whitsel EA, Witte JS, Xu J, Haiman C, Wilson JG, Kooperberg C, Stram D, Reiner AP, Tang H, Price AL. Leveraging population admixture to characterize the heritability of complex traits. Nat Genet. 2014 Dec; 46(12):1356-62. PMID: 25383972; PMCID: PMC4244251.
  9. Sankararaman S, Mallick S, Dannemann M, Prüfer K, Kelso J, Pääbo S, Patterson N, Reich D. The genomic landscape of Neanderthal ancestry in present-day humans. Nature. 2014 Mar 20; 507(7492):354-7. PMID: 24476815; PMCID: PMC4072735.
  10. Prüfer K, Racimo F, Patterson N, Jay F, Sankararaman S, Sawyer S, Heinze A, Renaud G, Sudmant PH, de Filippo C, Li H, Mallick S, Dannemann M, Fu Q, Kircher M, Kuhlwilm M, Lachmann M, Meyer M, Ongyerth M, Siebauer M, Theunert C, Tandon A, Moorjani P, Pickrell J, Mullikin JC, Vohr SH, Green RE, Hellmann I, Johnson PL, Blanche H, Cann H, Kitzman JO, Shendure J, Eichler EE, Lein ES, Bakken TE, Golovanova LV, Doronichev VB, Shunkov MV, Derevianko AP, Viola B, Slatkin M, Reich D, Kelso J, Pääbo S. The complete genome sequence of a Neanderthal from the Altai Mountains. Nature. 2014 Jan 2; 505(7481):43-9. PMID: 24352235; PMCID: PMC4031459.
  11. Bhatia G, Patterson N, Sankararaman S, Price AL. Estimating and interpreting FST: the impact of rare variants. Genome Res. 2013 Sep; 23(9):1514-21. PMID: 23861382; PMCID: PMC3759727.
  12. Pasaniuc B, Sankararaman S, Torgerson DG, Gignoux C, Zaitlen N, Eng C, Rodriguez-Cintron W, Chapela R, Ford JG, Avila PC, Rodriguez-Santana J, Chen GK, Le Marchand L, Henderson B, Reich D, Haiman CA, Gonzàlez Burchard E, Halperin E. Analysis of Latino populations from GALA and MEC studies reveals genomic loci with biased local ancestry estimation. Bioinformatics. 2013 Jun 1; 29(11):1407-15. PMID: 23572411; PMCID: PMC3661056.
  13. Sankararaman S, Patterson N, Li H, Pääbo S, Reich D. The date of interbreeding between Neandertals and modern humans. PLoS Genet. 2012; 8(10):e1002947. PMID: 23055938; PMCID: PMC3464203.
  14. Turchin MC, Chiang CW, Palmer CD, Sankararaman S, Reich D, Hirschhorn JN. Evidence of widespread selection on standing variation in Europe at height-associated SNPs. Nat Genet. 2012 Sep; 44(9):1015-9. PMID: 22902787; PMCID: PMC3480734.
  15. Baran Y, Pasaniuc B, Sankararaman S, Torgerson DG, Gignoux C, Eng C, Rodriguez-Cintron W, Chapela R, Ford JG, Avila PC, Rodriguez-Santana J, Burchard EG, Halperin E. Fast and accurate inference of local ancestry in Latino populations. Bioinformatics. 2012 May 15; 28(10):1359-67. PMID: 22495753; PMCID: PMC3348558.
  16. Bouchard-Côté A, Sankararaman S, Jordan MI. Phylogenetic inference via sequential Monte Carlo. Syst Biol. 2012 Jul; 61(4):579-93. PMID: 22223445; PMCID: PMC3376373.
  17. Hodgkinson CA, Enoch MA, Srivastava V, Cummins-Oman JS, Ferrier C, Iarikova P, Sankararaman S, Yamini G, Yuan Q, Zhou Z, Albaugh B, White KV, Shen PH, Goldman D. Genome-wide association identifies candidate genes that influence the human electroencephalogram. Proc Natl Acad Sci U S A. 2010 May 11; 107(19):8695-700. PMID: 20421487; PMCID: PMC2889314.
  18. Sankararaman S, Sha F, Kirsch JF, Jordan MI, Sjölander K. Active site prediction using evolutionary and structural information. Bioinformatics. 2010 Mar 1; 26(5):617-24. PMID: 20080507; PMCID: PMC2828116.
  19. Sankararaman S, Obozinski G, Jordan MI, Halperin E. Genomic privacy and limits of individual detection in a pool. Nat Genet. 2009 Sep; 41(9):965-7. PMID: 19701190.
    View in: PubMed
  20. Alterovitz R, Arvey A, Sankararaman S, Dallett C, Freund Y, Sjölander K. ResBoost: characterizing and predicting catalytic residues in enzymes. BMC Bioinformatics. 2009; 10:197. PMID: 19558703; PMCID: PMC2713229.
  21. Pasaniuc B, Sankararaman S, Kimmel G, Halperin E. Inference of locus-specific ancestry in closely related populations. Bioinformatics. 2009 Jun 15; 25(12):i213-21. PMID: 19477991; PMCID: PMC2687951.
  22. Sankararaman S, Kolaczkowski B, Sjölander K. INTREPID: a web server for prediction of functionally important residues by evolutionary analysis. Nucleic Acids Res. 2009 Jul; 37(Web Server issue):W390-5. PMID: 19443452; PMCID: PMC2703888.
  23. Sankararaman S, Sjölander K. INTREPID--INformation-theoretic TREe traversal for Protein functional site IDentification. Bioinformatics. 2008 Nov 1; 24(21):2445-52. PMID: 18776193; PMCID: PMC2572704.
  24. Skibola CF, Bracci PM, Halperin E, Nieters A, Hubbard A, Paynter RA, Skibola DR, Agana L, Becker N, Tressler P, Forrest MS, Sankararaman S, Conde L, Holly EA, Smith MT. Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma. PLoS One. 2008; 3(7):e2816. PMID: 18636124; PMCID: PMC2474696.
  25. Sankararaman S, Kimmel G, Halperin E, Jordan MI. On the inference of ancestries in admixed populations. Genome Res. 2008 Apr; 18(4):668-75. PMID: 18353809; PMCID: PMC2279254.
  26. Sankararaman S, Sridhar S, Kimmel G, Halperin E. Estimating local ancestry in admixed populations. Am J Hum Genet. 2008 Feb; 82(2):290-303. PMID: 18252211; PMCID: PMC2664993.
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