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Calum Archibald MacRae, Ph.D., M.D.

TitleAssociate Professor of Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressBrigham and Womens Hospital
Cardiovascular Disease, Medicine, Thorn 1127A
75 Francis St
Boston MA 02115
Phone857/307-0301
Fax856/307-0300
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 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Guan J, Mishra S, Qiu Y, Shi J, Trudeau K, Las G, Liesa M, Shirihai OS, Connors LH, Seldin DC, Falk RH, MacRae CA, Liao R. Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain-mediated cardiotoxicity. EMBO Mol Med. 2014; 6(11):1493-507.
    View in: PubMed
  2. Roder K, Werdich AA, Li W, Liu M, Kim TY, Organ-Darling LE, Moshal KS, Hwang JM, Lu Y, Choi BR, MacRae CA, Koren G. RING Finger Protein RNF207, a Novel Regulator of Cardiac Excitation. J Biol Chem. 2014 Dec 5; 289(49):33730-40.
    View in: PubMed
  3. Hariharan V, Asimaki A, Michaelson JE, Plovie E, MacRae CA, Saffitz JE, Huang H. Arrhythmogenic right ventricular cardiomyopathy mutations alter shear response without changes in cell-cell adhesion. Cardiovasc Res. 2014 Nov 1; 104(2):280-9.
    View in: PubMed
  4. Kim AD, Melick CH, Clements WK, Stachura DL, Distel M, Panáková D, MacRae C, Mork LA, Crump JG, Traver D. Discrete Notch signaling requirements in the specification of hematopoietic stem cells. EMBO J. 2014 Oct 16; 33(20):2363-73.
    View in: PubMed
  5. Stitziel NO, MacRae CA. A clinical approach to inherited premature coronary artery disease. Circ Cardiovasc Genet. 2014 Aug; 7(4):558-64.
    View in: PubMed
  6. Triedman JK, MacRae C. Searching for a Rosetta Stone: Genetic data and clinical patient management. Heart Rhythm. 2014 Oct; 11(10):1714-5.
    View in: PubMed
  7. Asimaki A, Kapoor S, Plovie E, Karin Arndt A, Adams E, Liu Z, James CA, Judge DP, Calkins H, Churko J, Wu JC, MacRae CA, Kléber AG, Saffitz JE. Identification of a new modulator of the intercalated disc in a zebrafish model of arrhythmogenic cardiomyopathy. Sci Transl Med. 2014 Jun 11; 6(240):240ra74.
    View in: PubMed
  8. Pieperhoff S, Wilson KS, Baily J, de Mora K, Maqsood S, Vass S, Taylor J, Del-Pozo J, MacRae CA, Mullins JJ, Denvir MA. Heart on a plate: histological and functional assessment of isolated adult zebrafish hearts maintained in culture. PLoS One. 2014; 9(5):e96771.
    View in: PubMed
  9. Arndt AK, Macrae CA. Genetic testing in cardiovascular diseases. Curr Opin Cardiol. 2014 May; 29(3):235-40.
    View in: PubMed
  10. Abrams DJ, Macrae CA. Long QT Syndrome. Circulation. 2014 Apr 8; 129(14):1524-9.
    View in: PubMed
  11. Vassy JL, Lautenbach DM, McLaughlin HM, Kong SW, Christensen KD, Krier J, Kohane IS, Feuerman LZ, Blumenthal-Barby J, Roberts JS, Lehmann LS, Ho CY, Ubel PA, Macrae CA, Seidman CE, Murray MF, McGuire AL, Rehm HL, Green RC. The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine. Trials. 2014; 15(1):85.
    View in: PubMed
  12. Macrae CA, Vasan RS. Clinically relevant functional annotation of genotype. Circ Cardiovasc Genet. 2014 Feb 1; 7(1):2-3.
    View in: PubMed
  13. Zhao L, Borikova AL, Ben-Yair R, Guner-Ataman B, Macrae CA, Lee RT, Burns CG, Burns CE. Notch signaling regulates cardiomyocyte proliferation during zebrafish heart regeneration. Proc Natl Acad Sci U S A. 2014 Jan 28; 111(4):1403-8.
    View in: PubMed
  14. Arndt AK, Macrae CA, Klaassen S. Reponse to de leeuw and houge. Am J Hum Genet. 2014 Jan 2; 94(1):154-5.
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  15. Musso G, Tasan M, Mosimann C, Beaver JE, Plovie E, Carr LA, Chua HN, Dunham J, Zuberi K, Rodriguez H, Morris Q, Zon L, Roth FP, Macrae CA. Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish. Development. 2014 Jan; 141(1):224-35.
    View in: PubMed
  16. Becker JR, Chatterjee S, Robinson TY, Bennett JS, Panáková D, Galindo CL, Zhong L, Shin JT, Coy SM, Kelly AE, Roden DM, Lim CC, Macrae CA. Differential activation of natriuretic peptide receptors modulates cardiomyocyte proliferation during development. Development. 2014 Jan; 141(2):335-45.
    View in: PubMed
  17. MacRae CA. Mendelian forms of structural cardiovascular disease. Curr Cardiol Rep. 2013 Oct; 15(10):399.
    View in: PubMed
  18. Icli B, Wara AK, Moslehi J, Sun X, Plovie E, Cahill M, Marchini JF, Schissler A, Padera RF, Shi J, Cheng HW, Raghuram S, Arany Z, Liao R, Croce K, Macrae C, Feinberg MW. MicroRNA-26a Regulates Pathological and Physiological Angiogenesis by Targeting BMP/SMAD1 Signaling. Circ Res. 2013 Nov 8; 113(11):1231-41.
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  19. Kapur S, Macrae CA. The developmental basis of adult arrhythmia: atrial fibrillation as a paradigm. Front Physiol. 2013; 4:221.
    View in: PubMed
  20. Guan J, Mishra S, Shi J, Plovie E, Qiu Y, Cao X, Gianni D, Jiang B, Del Monte F, Connors LH, Seldin DC, Lavatelli F, Rognoni P, Palladini G, Merlini G, Falk RH, Semigran MJ, Dec GW, Macrae CA, Liao R. Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicity. Basic Res Cardiol. 2013 Sep; 108(5):378.
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  21. Huang CJ, Wilson V, Pennings S, Macrae CA, Mullins J. Sequential effects of spadetail, one-eyed pinhead and no tail on midline convergence of nephric primordia during zebrafish embryogenesis. Dev Biol. 2013 Dec 15; 384(2):290-300.
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  22. Arndt AK, Schafer S, Drenckhahn JD, Sabeh MK, Plovie ER, Caliebe A, Klopocki E, Musso G, Werdich AA, Kalwa H, Heinig M, Padera RF, Wassilew K, Bluhm J, Harnack C, Martitz J, Barton PJ, Greutmann M, Berger F, Hubner N, Siebert R, Kramer HH, Cook SA, MacRae CA, Klaassen S. Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy. Am J Hum Genet. 2013 Jul 11; 93(1):67-77.
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  23. Jay SM, Murthy AC, Hawkins JF, Wortzel JR, Steinhauser ML, Alvarez LM, Gannon J, Macrae CA, Griffith LG, Lee RT. An engineered bivalent neuregulin protects against doxorubicin-induced cardiotoxicity with reduced proneoplastic potential. Circulation. 2013 Jul 9; 128(2):152-61.
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  24. Macrae C. The author's reply. Heart. 2013 Sep; 99(18):1374.
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  25. Valente AM, Lakdawala NK, Powell AJ, Evans SP, Cirino AL, Orav EJ, MacRae CA, Colan SD, Ho CY. Comparison of echocardiographic and cardiac magnetic resonance imaging in hypertrophic cardiomyopathy sarcomere mutation carriers without left ventricular hypertrophy. Circ Cardiovasc Genet. 2013 Jun; 6(3):230-7.
    View in: PubMed
  26. Mishra S, Guan J, Plovie E, Seldin DC, Connors LH, Merlini G, Falk RH, MacRae CA, Liao R. Human amyloidogenic light chain proteins result in cardiac dysfunction, cell death, and early mortality in zebrafish. Am J Physiol Heart Circ Physiol. 2013 Jul 1; 305(1):H95-103.
    View in: PubMed
  27. Kolpa HJ, Peal DS, Lynch SN, Giokas AC, Ghatak S, Misra S, Norris RA, Macrae CA, Markwald RR, Ellinor P, Bischoff J, Milan DJ. miR-21 represses Pdcd4 during cardiac valvulogenesis. Development. 2013 May; 140(10):2172-80.
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  28. Nath AK, Roberts LD, Liu Y, Mahon SB, Kim S, Ryu JH, Werdich A, Januzzi JL, Boss GR, Rockwood GA, MacRae CA, Brenner M, Gerszten RE, Peterson RT. Chemical and metabolomic screens identify novel biomarkers and antidotes for cyanide exposure. FASEB J. 2013 May; 27(5):1928-38.
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  29. MacRae CA. Recent advances in in vivo screening for antiarrhythmic drugs. Expert Opin Drug Discov. 2013 Feb; 8(2):131-41.
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  30. MacRae CA. Action and the actionability in exome variation. Circ Cardiovasc Genet. 2012 Dec; 5(6):597-8.
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  31. Jin S, Sarkar KS, Jin YN, Liu Y, Kokel D, Van Ham TJ, Roberts LD, Gerszten RE, Macrae CA, Peterson RT. An in vivo zebrafish screen identifies organophosphate antidotes with diverse mechanisms of action. J Biomol Screen. 2013 Jan; 18(1):108-15.
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  32. MacRae CA. Pattern recognition: combining informatics and genetics to re-evaluate conduction disease. Heart. 2012 Sep; 98(17):1263-4.
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  33. Werdich AA, Brzezinski A, Jeyaraj D, Khaled Sabeh M, Ficker E, Wan X, McDermott BM, Macrae CA, Rosenbaum DS. The zebrafish as a novel animal model to study the molecular mechanisms of mechano-electrical feedback in the heart. Prog Biophys Mol Biol. 2012 Oct-Nov; 110(2-3):154-65.
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  34. Rothman RD, Baggish AL, O'Callaghan C, Lowry PA, Bhatt AB, MacRae CA, Yannekis G, Sanborn DM, Mela T, Yeh RW, Palacios I, Vlahakes GJ, Fifer MA. Management strategy in 249 consecutive patients with obstructive hypertrophic cardiomyopathy referred to a dedicated program. Am J Cardiol. 2012 Oct 15; 110(8):1169-74.
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  35. Ashley EA, Hershberger RE, Caleshu C, Ellinor PT, Garcia JG, Herrington DM, Ho CY, Johnson JA, Kittner SJ, Macrae CA, Mudd-Martin G, Rader DJ, Roden DM, Scholes D, Sellke FW, Towbin JA, Van Eyk J, Worrall BB. Genetics and cardiovascular disease: a policy statement from the American Heart Association. Circulation. 2012 Jul 3; 126(1):142-57.
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  36. Guo W, Schafer S, Greaser ML, Radke MH, Liss M, Govindarajan T, Maatz H, Schulz H, Li S, Parrish AM, Dauksaite V, Vakeel P, Klaassen S, Gerull B, Thierfelder L, Regitz-Zagrosek V, Hacker TA, Saupe KW, Dec GW, Ellinor PT, MacRae CA, Spallek B, Fischer R, Perrot A, Özcelik C, Saar K, Hubner N, Gotthardt M. RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing. Nat Med. 2012 May; 18(5):766-73.
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  37. Sabeh MK, Kekhia H, Macrae CA. Optical mapping in the developing zebrafish heart. Pediatr Cardiol. 2012 Aug; 33(6):916-22.
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  38. Rider SA, Tucker CS, del-Pozo J, Rose KN, MacRae CA, Bailey MA, Mullins JJ. Techniques for the in vivo assessment of cardio-renal function in zebrafish (Danio rerio) larvae. J Physiol. 2012 Apr 15; 590(Pt 8):1803-9.
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  39. Becker JR, Robinson TY, Sachidanandan C, Kelly AE, Coy S, Peterson RT, MacRae CA. In vivo natriuretic peptide reporter assay identifies chemical modifiers of hypertrophic cardiomyopathy signalling. Cardiovasc Res. 2012 Mar 1; 93(3):463-70.
    View in: PubMed
  40. Lee MS, Macrae CA. Revisiting risk stratification in hypertrophic cardiomyopathy: do we need to start from scratch? Heart Rhythm. 2012 Jan; 9(1):64-5.
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  41. Peterson RT, Macrae CA. Systematic approaches to toxicology in the zebrafish. Annu Rev Pharmacol Toxicol. 2012; 52:433-53.
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  42. Refaat MM, Lubitz SA, Makino S, Islam Z, Frangiskakis JM, Mehdi H, Gutmann R, Zhang ML, Bloom HL, MacRae CA, Dudley SC, Shalaby AA, Weiss R, McNamara DM, London B, Ellinor PT. Genetic variation in the alternative splicing regulator RBM20 is associated with dilated cardiomyopathy. Heart Rhythm. 2012 Mar; 9(3):390-6.
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  43. MacRae CA, Vasan RS. Next-generation genome-wide association studies: time to focus on phenotype? Circ Cardiovasc Genet. 2011 Aug 1; 4(4):334-6.
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  44. Wang J, Panáková D, Kikuchi K, Holdway JE, Gemberling M, Burris JS, Singh SP, Dickson AL, Lin YF, Sabeh MK, Werdich AA, Yelon D, Macrae CA, Poss KD. The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion. Development. 2011 Aug; 138(16):3421-30.
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  45. Wythe JD, Jurynec MJ, Urness LD, Jones CA, Sabeh MK, Werdich AA, Sato M, Yost HJ, Grunwald DJ, Macrae CA, Li DY. Hadp1, a newly identified pleckstrin homology domain protein, is required for cardiac contractility in zebrafish. Dis Model Mech. 2011 Sep; 4(5):607-21.
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  46. Naunheim MR, Walcott BP, Nahed BV, MacRae CA, Levinson JR, Ogilvy CS. Arterial tortuosity syndrome with multiple intracranial aneurysms: a case report. Arch Neurol. 2011 Mar; 68(3):369-71.
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  47. Becker JR, Deo RC, Werdich AA, Panàkovà D, Coy S, MacRae CA. Human cardiomyopathy mutations induce myocyte hyperplasia and activate hypertrophic pathways during cardiogenesis in zebrafish. Dis Model Mech. 2011 May; 4(3):400-10.
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  48. Boström P, Mann N, Wu J, Quintero PA, Plovie ER, Panáková D, Gupta RK, Xiao C, MacRae CA, Rosenzweig A, Spiegelman BM. C/EBPß controls exercise-induced cardiac growth and protects against pathological cardiac remodeling. Cell. 2010 Dec 23; 143(7):1072-83.
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  49. Deo RC, MacRae CA. Clinical screening and genetic testing. Clin Lab Med. 2010 Dec; 30(4):775-84.
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  50. Assimes TL, Hólm H, Kathiresan S, Reilly MP, Thorleifsson G, Voight BF, Erdmann J, Willenborg C, Vaidya D, Xie C, Patterson CC, Morgan TM, Burnett MS, Li M, Hlatky MA, Knowles JW, Thompson JR, Absher D, Iribarren C, Go A, Fortmann SP, Sidney S, Risch N, Tang H, Myers RM, Berger K, Stoll M, Shah SH, Thorgeirsson G, Andersen K, Havulinna AS, Herrera JE, Faraday N, Kim Y, Kral BG, Mathias RA, Ruczinski I, Suktitipat B, Wilson AF, Yanek LR, Becker LC, Linsel-Nitschke P, Lieb W, König IR, Hengstenberg C, Fischer M, Stark K, Reinhard W, Winogradow J, Grassl M, Grosshennig A, Preuss M, Schreiber S, Wichmann HE, Meisinger C, Yee J, Friedlander Y, Do R, Meigs JB, Williams G, Nathan DM, MacRae CA, Qu L, Wilensky RL, Matthai WH, Qasim AN, Hakonarson H, Pichard AD, Kent KM, Satler L, Lindsay JM, Waksman R, Knouff CW, Waterworth DM, Walker MC, Mooser VE, Marrugat J, Lucas G, Subirana I, Sala J, Ramos R, Martinelli N, Olivieri O, Trabetti E, Malerba G, Pignatti PF, Guiducci C, Mirel D, Parkin M, Hirschhorn JN, Asselta R, Duga S, Musunuru K, Daly MJ, Purcell S, Eifert S, Braund PS, Wright BJ, Balmforth AJ, Ball SG, Ouwehand WH, Deloukas P, Scholz M, Cambien F, Huge A, Scheffold T, Salomaa V, Girelli D, Granger CB, Peltonen L, McKeown PP, Altshuler D, Melander O, Devaney JM, Epstein SE, Rader DJ, Elosua R, Engert JC, Anand SS, Hall AS, Ziegler A, O'Donnell CJ, Spertus JA, Siscovick D, Schwartz SM, Becker D, Thorsteinsdottir U, Stefansson K, Schunkert H, Samani NJ, Quertermous T. Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol. 2010 Nov 2; 56(19):1552-63.
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  51. Sogah VM, Serluca FC, Fishman MC, Yelon DL, Macrae CA, Mably JD. Distinct troponin C isoform requirements in cardiac and skeletal muscle. Dev Dyn. 2010 Nov; 239(11):3115-23.
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  52. Deo RC, MacRae CA. The zebrafish: scalable in vivo modeling for systems biology. Wiley Interdiscip Rev Syst Biol Med. 2011 May-Jun; 3(3):335-46.
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  53. Panáková D, Werdich AA, Macrae CA. Wnt11 patterns a myocardial electrical gradient through regulation of the L-type Ca(2+) channel. Nature. 2010 Aug 12; 466(7308):874-8.
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  54. Sabeh MK, MacRae CA. The genetics of atrial fibrillation. Curr Opin Cardiol. 2010 May; 25(3):186-91.
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  55. Albert CM, MacRae CA, Chasman DI, VanDenburgh M, Buring JE, Manson JE, Cook NR, Newton-Cheh C. Common variants in cardiac ion channel genes are associated with sudden cardiac death. Circ Arrhythm Electrophysiol. 2010 Jun; 3(3):222-9.
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  56. Shin JT, Pomerantsev EV, Mably JD, MacRae CA. High-resolution cardiovascular function confirms functional orthology of myocardial contractility pathways in zebrafish. Physiol Genomics. 2010 Jul 7; 42(2):300-9.
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  57. MacRae CA. The genetics of congestive heart failure. Heart Fail Clin. 2010 Apr; 6(2):223-30.
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  58. Deo RC, MacRae CA. Clinical screening and genetic testing. Heart Fail Clin. 2010 Apr; 6(2):231-8.
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  59. Ellinor PT, MacRae CA, Thierfelder L. Arrhythmogenic right ventricular cardiomyopathy. Heart Fail Clin. 2010 Apr; 6(2):161-77.
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  60. MacRae CA. Preface. Genetic studies of primary forms of heart failure. Heart Fail Clin. 2010 Apr; 6(2):xv-xvi.
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  61. Kikuchi K, Holdway JE, Werdich AA, Anderson RM, Fang Y, Egnaczyk GF, Evans T, Macrae CA, Stainier DY, Poss KD. Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes. Nature. 2010 Mar 25; 464(7288):601-5.
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  62. Gritli S, Ben Salah M, Shili A, Robson CD, Ferjaoui M, Hendaoui L, Belhani A, Jilani SB, Gusella JF, Macrae CA. Association of the long QT syndrome With goiter and deafness. Am J Cardiol. 2010 Mar 1; 105(5):681-6.
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  63. Ellinor PT, Lunetta KL, Glazer NL, Pfeufer A, Alonso A, Chung MK, Sinner MF, de Bakker PI, Mueller M, Lubitz SA, Fox E, Darbar D, Smith NL, Smith JD, Schnabel RB, Soliman EZ, Rice KM, Van Wagoner DR, Beckmann BM, van Noord C, Wang K, Ehret GB, Rotter JI, Hazen SL, Steinbeck G, Smith AV, Launer LJ, Harris TB, Makino S, Nelis M, Milan DJ, Perz S, Esko T, Köttgen A, Moebus S, Newton-Cheh C, Li M, Möhlenkamp S, Wang TJ, Kao WH, Vasan RS, Nöthen MM, MacRae CA, Stricker BH, Hofman A, Uitterlinden AG, Levy D, Boerwinkle E, Metspalu A, Topol EJ, Chakravarti A, Gudnason V, Psaty BM, Roden DM, Meitinger T, Wichmann HE, Witteman JC, Barnard J, Arking DE, Benjamin EJ, Heckbert SR, Kääb S. Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet. 2010 Mar; 42(3):240-4.
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  64. Lamont RE, Vu W, Carter AD, Serluca FC, MacRae CA, Childs SJ. Hedgehog signaling via angiopoietin1 is required for developmental vascular stability. Mech Dev. 2010 Apr; 127(3-4):159-68.
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  65. Peal DS, Burns CG, Macrae CA, Milan D. Chondroitin sulfate expression is required for cardiac atrioventricular canal formation. Dev Dyn. 2009 Dec; 238(12):3103-10.
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  66. Saffitz JE, Macrae CA. Mutations in desmosomal protein genes and the pathogenesis of arrhythmogenic right ventricular cardiomyopathy. Heart Rhythm. 2010 Jan; 7(1):30-2.
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  67. MacRae CA. Closer look at genetic testing in long-QT syndrome: will DNA diagnostics ever be enough? Circulation. 2009 Nov 3; 120(18):1745-8.
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  68. Macrae CA, McKenna WJ. Splicing and dilated cardiomyopathy one gene to rule them all? J Am Coll Cardiol. 2009 Sep 1; 54(10):942-3.
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  69. Milan DJ, Kim AM, Winterfield JR, Jones IL, Pfeufer A, Sanna S, Arking DE, Amsterdam AH, Sabeh KM, Mably JD, Rosenbaum DS, Peterson RT, Chakravarti A, Kääb S, Roden DM, MacRae CA. Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization. Circulation. 2009 Aug 18; 120(7):553-9.
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  70. MacRae CA. Symptoms in atrial fibrillation: why keep score? Circ Arrhythm Electrophysiol. 2009 Jun; 2(3):215-7.
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  71. Watanabe H, Kaiser DW, Makino S, MacRae CA, Ellinor PT, Wasserman BS, Kannankeril PJ, Donahue BS, Roden DM, Darbar D. ACE I/D polymorphism associated with abnormal atrial and atrioventricular conduction in lone atrial fibrillation and structural heart disease: implications for electrical remodeling. Heart Rhythm. 2009 Sep; 6(9):1327-32.
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  72. Das S, Makino S, Melman YF, Shea MA, Goyal SB, Rosenzweig A, Macrae CA, Ellinor PT. Mutation in the S3 segment of KCNQ1 results in familial lone atrial fibrillation. Heart Rhythm. 2009 Aug; 6(8):1146-53.
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  73. Ho CY, MacRae CA. Defining the pathogenicity of DNA sequence variation. Circ Cardiovasc Genet. 2009 Apr; 2(2):95-7.
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  74. Kathiresan S, Voight BF, Purcell S, Musunuru K, Ardissino D, Mannucci PM, Anand S, Engert JC, Samani NJ, Schunkert H, Erdmann J, Reilly MP, Rader DJ, Morgan T, Spertus JA, Stoll M, Girelli D, McKeown PP, Patterson CC, Siscovick DS, O'Donnell CJ, Elosua R, Peltonen L, Salomaa V, Schwartz SM, Melander O, Altshuler D, Ardissino D, Merlini PA, Berzuini C, Bernardinelli L, Peyvandi F, Tubaro M, Celli P, Ferrario M, Fetiveau R, Marziliano N, Casari G, Galli M, Ribichini F, Rossi M, Bernardi F, Zonzin P, Piazza A, Mannucci PM, Schwartz SM, Siscovick DS, Yee J, Friedlander Y, Elosua R, Marrugat J, Lucas G, Subirana I, Sala J, Ramos R, Kathiresan S, Meigs JB, Williams G, Nathan DM, MacRae CA, O'Donnell CJ, Salomaa V, Havulinna AS, Peltonen L, Melander O, Berglund G, Voight BF, Kathiresan S, Hirschhorn JN, Asselta R, Duga S, Spreafico M, Musunuru K, Daly MJ, Purcell S, Voight BF, Purcell S, Nemesh J, Korn JM, McCarroll SA, Schwartz SM, Yee J, Kathiresan S, Lucas G, Subirana I, Elosua R, Surti A, Guiducci C, Gianniny L, Mirel D, Parkin M, Burtt N, Gabriel SB, Samani NJ, Thompson JR, Braund PS, Wright BJ, Balmforth AJ, Ball SG, Hall A, Schunkert H, Erdmann J, Linsel-Nitschke P, Lieb W, Ziegler A, König I, Hengstenberg C, Fischer M, Stark K, Grosshennig A, Preuss M, Wichmann HE, Schreiber S, Schunkert H, Samani NJ, Erdmann J, Ouwehand W, Hengstenberg C, Deloukas P, Scholz M, Cambien F, Reilly MP, Li M, Chen Z, Wilensky R, Matthai W, Qasim A, Hakonarson HH, Devaney J, Burnett MS, Pichard AD, Kent KM, Satler L, Lindsay JM, Waksman R, Knouff CW, Waterworth DM, Walker MC, Mooser V, Epstein SE, Rader DJ, Scheffold T, Berger K, Stoll M, Huge A, Girelli D, Martinelli N, Olivieri O, Corrocher R, Morgan T, Spertus JA, McKeown P, Patterson CC, Schunkert H, Erdmann E, Linsel-Nitschke P, Lieb W, Ziegler A, König IR, Hengstenberg C, Fischer M, Stark K, Grosshennig A, Preuss M, Wichmann HE, Schreiber S, Hólm H, Thorleifsson G, Thorsteinsdottir U, Stefansson K, Engert JC, Do R, Xie C, Anand S, Kathiresan S, Ardissino D, Mannucci PM, Siscovick D, O'Donnell CJ, Samani NJ, Melander O, Elosua R, Peltonen L, Salomaa V, Schwartz SM, Altshuler D. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet. 2009 Mar; 41(3):334-41.
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  75. Milan DJ, Macrae CA. Zebrafish genetic models for arrhythmia. Prog Biophys Mol Biol. 2008 Oct-Nov; 98(2-3):301-8.
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  76. Kääb S, Darbar D, van Noord C, Dupuis J, Pfeufer A, Newton-Cheh C, Schnabel R, Makino S, Sinner MF, Kannankeril PJ, Beckmann BM, Choudry S, Donahue BS, Heeringa J, Perz S, Lunetta KL, Larson MG, Levy D, MacRae CA, Ruskin JN, Wacker A, Schömig A, Wichmann HE, Steinbeck G, Meitinger T, Uitterlinden AG, Witteman JC, Roden DM, Benjamin EJ, Ellinor PT. Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation. Eur Heart J. 2009 Apr; 30(7):813-9.
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  77. Vasan RS, MacRae CA. A dream, a journey, and a promise: the inauguration of Circulation: Cardiovascular Genetics. Circ Cardiovasc Genet. 2008 Oct; 1(1):1-2.
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  78. Wang L, Sewell WF, Kim SD, Shin JT, MacRae CA, Zon LI, Seidman JG, Seidman CE. Eya4 regulation of Na+/K+-ATPase is required for sensory system development in zebrafish. Development. 2008 Oct; 135(20):3425-34.
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  79. Jaggard MK, MacRae C, Ifeacho S, Robinson S, Tolley NS. New presentation of familial medullary thyroid carcinoma in 87-year-old patient with high-risk RET proto-oncogene codon 620 mutation. J Laryngol Otol. 2009 Jul; 123(7):796-800.
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  80. Ellinor PT, MacRae CA. Ion channel mutations in AF: signal or noise? Heart Rhythm. 2008 Mar; 5(3):436-7.
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  81. Yeh JR, Munson KM, Chao YL, Peterson QP, Macrae CA, Peterson RT. AML1-ETO reprograms hematopoietic cell fate by downregulating scl expression. Development. 2008 Jan; 135(2):401-10.
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  82. Ellinor PT, Yi BA, MacRae CA. Genetics of atrial fibrillation. Med Clin North Am. 2008 Jan; 92(1):41-51, x.
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  83. Albert CM, Nam EG, Rimm EB, Jin HW, Hajjar RJ, Hunter DJ, MacRae CA, Ellinor PT. Cardiac sodium channel gene variants and sudden cardiac death in women. Circulation. 2008 Jan 1; 117(1):16-23.
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  84. Deo R, MacRae CA. The genetics of cardiomyopathies: what clinicians should know. Curr Heart Fail Rep. 2007 Dec; 4(4):229-35.
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  85. Ellinor PT, Nam EG, Shea MA, Milan DJ, Ruskin JN, MacRae CA. Cardiac sodium channel mutation in atrial fibrillation. Heart Rhythm. 2008 Jan; 5(1):99-105.
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  86. Gudbjartsson DF, Arnar DO, Helgadottir A, Gretarsdottir S, Holm H, Sigurdsson A, Jonasdottir A, Baker A, Thorleifsson G, Kristjansson K, Palsson A, Blondal T, Sulem P, Backman VM, Hardarson GA, Palsdottir E, Helgason A, Sigurjonsdottir R, Sverrisson JT, Kostulas K, Ng MC, Baum L, So WY, Wong KS, Chan JC, Furie KL, Greenberg SM, Sale M, Kelly P, MacRae CA, Smith EE, Rosand J, Hillert J, Ma RC, Ellinor PT, Thorgeirsson G, Gulcher JR, Kong A, Thorsteinsdottir U, Stefansson K. Variants conferring risk of atrial fibrillation on chromosome 4q25. Nature. 2007 Jul 19; 448(7151):353-7.
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  87. Gregory SA, MacRae CA, Aziz K, Sims KB, Schmahmann JD, Kardan A, Morss AM, Ellinor PT, Tawakol A, Fischman AJ, Gewirtz H. Myocardial blood flow and oxygen consumption in patients with Friedreich's ataxia prior to the onset of cardiomyopathy. Coron Artery Dis. 2007 Feb; 18(1):15-22.
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  88. Maree AO, Jneid H, Palacios IF, Rosenfield K, MacRae CA, Fitzgerald DJ. Growth arrest specific gene (GAS) 6 modulates platelet thrombus formation and vascular wall homeostasis and represents an attractive drug target. Curr Pharm Des. 2007; 13(26):2656-61.
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  89. Lee JS, Yu Q, Shin JT, Sebzda E, Bertozzi C, Chen M, Mericko P, Stadtfeld M, Zhou D, Cheng L, Graf T, MacRae CA, Lepore JJ, Lo CW, Kahn ML. Klf2 is an essential regulator of vascular hemodynamic forces in vivo. Dev Cell. 2006 Dec; 11(6):845-57.
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  90. Heuser A, Plovie ER, Ellinor PT, Grossmann KS, Shin JT, Wichter T, Basson CT, Lerman BB, Sasse-Klaassen S, Thierfelder L, MacRae CA, Gerull B. Mutant desmocollin-2 causes arrhythmogenic right ventricular cardiomyopathy. Am J Hum Genet. 2006 Dec; 79(6):1081-8.
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  91. Ellinor PT, Choudry S, Macrae CA. Genetics of atrial fibrillation. Future Cardiol. 2006 Sep; 2(5):579-84.
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  92. van Kimmenade RR, Januzzi JL, Ellinor PT, Sharma UC, Bakker JA, Low AF, Martinez A, Crijns HJ, MacRae CA, Menheere PP, Pinto YM. Utility of amino-terminal pro-brain natriuretic peptide, galectin-3, and apelin for the evaluation of patients with acute heart failure. J Am Coll Cardiol. 2006 Sep 19; 48(6):1217-24.
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  93. Ellinor PT, Petrov-Kondratov VI, Zakharova E, Nam EG, MacRae CA. Potassium channel gene mutations rarely cause atrial fibrillation. BMC Med Genet. 2006; 7:70.
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  94. MacRae CA, Birchmeier W, Thierfelder L. Arrhythmogenic right ventricular cardiomyopathy: moving toward mechanism. J Clin Invest. 2006 Jul; 116(7):1825-8.
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  95. Ellinor PT, Sasse-Klaassen S, Probst S, Gerull B, Shin JT, Toeppel A, Heuser A, Michely B, Yoerger DM, Song BS, Pilz B, Krings G, Coplin B, Lange PE, Dec GW, Hennies HC, Thierfelder L, MacRae CA. A novel locus for dilated cardiomyopathy, diffuse myocardial fibrosis, and sudden death on chromosome 10q25-26. J Am Coll Cardiol. 2006 Jul 4; 48(1):106-11.
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  96. Ellinor PT, Low A, Patton KK, Shea MA, MacRae CA. C-Reactive protein in lone atrial fibrillation. Am J Cardiol. 2006 May 1; 97(9):1346-50.
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  97. Burns CG, MacRae CA. Purification of hearts from zebrafish embryos. Biotechniques. 2006 Mar; 40(3):274, 276, 278 passim.
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  98. Milan DJ, Jones IL, Ellinor PT, MacRae CA. In vivo recording of adult zebrafish electrocardiogram and assessment of drug-induced QT prolongation. Am J Physiol Heart Circ Physiol. 2006 Jul; 291(1):H269-73.
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  99. Milan DJ, Giokas AC, Serluca FC, Peterson RT, MacRae CA. Notch1b and neuregulin are required for specification of central cardiac conduction tissue. Development. 2006 Mar; 133(6):1125-32.
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  100. Ellinor PT, Yoerger DM, Ruskin JN, MacRae CA. Familial aggregation in lone atrial fibrillation. Hum Genet. 2005 Nov; 118(2):179-84.
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  101. Ellinor PT, Low AF, Macrae CA. Reduced apelin levels in lone atrial fibrillation. Eur Heart J. 2006 Jan; 27(2):222-6.
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  102. Low AF, O'Donnell CJ, Kathiresan S, Everett B, Chae CU, Shaw SY, Ellinor PT, MacRae CA. Aging syndrome genes and premature coronary artery disease. BMC Med Genet. 2005 Oct 31; 6:38.
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  103. Shin JT, Priest JR, Ovcharenko I, Ronco A, Moore RK, Burns CG, MacRae CA. Human-zebrafish non-coding conserved elements act in vivo to regulate transcription. Nucleic Acids Res. 2005; 33(17):5437-45.
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  104. Burns CG, Milan DJ, Grande EJ, Rottbauer W, MacRae CA, Fishman MC. High-throughput assay for small molecules that modulate zebrafish embryonic heart rate. Nat Chem Biol. 2005 Oct; 1(5):263-4.
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  105. Milan DJ, MacRae CA. Animal models for arrhythmias. Cardiovasc Res. 2005 Aug 15; 67(3):426-37.
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  106. Mahon NG, Murphy RT, MacRae CA, Caforio AL, Elliott PM, McKenna WJ. Echocardiographic evaluation in asymptomatic relatives of patients with dilated cardiomyopathy reveals preclinical disease. Ann Intern Med. 2005 Jul 19; 143(2):108-15.
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  107. Patton KK, Zacks ES, Chang JY, Shea MA, Ruskin JN, Macrae CA, Ellinor PT. Clinical subtypes of lone atrial fibrillation. Pacing Clin Electrophysiol. 2005 Jul; 28(7):630-8.
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  108. Murphy RT, Mogensen J, McGarry K, Bahl A, Evans A, Osman E, Syrris P, Gorman G, Farrell M, Holton JL, Hanna MG, Hughes S, Elliott PM, Macrae CA, McKenna WJ. Adenosine monophosphate-activated protein kinase disease mimicks hypertrophic cardiomyopathy and Wolff-Parkinson-White syndrome: natural history. J Am Coll Cardiol. 2005 Mar 15; 45(6):922-30.
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  109. Schönberger J, Wang L, Shin JT, Kim SD, Depreux FF, Zhu H, Zon L, Pizard A, Kim JB, Macrae CA, Mungall AJ, Seidman JG, Seidman CE. Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss. Nat Genet. 2005 Apr; 37(4):418-22.
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  110. Ellinor PT, Low AF, Patton KK, Shea MA, Macrae CA. Discordant atrial natriuretic peptide and brain natriuretic peptide levels in lone atrial fibrillation. J Am Coll Cardiol. 2005 Jan 4; 45(1):82-6.
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  111. MacRae CA, Ellinor PT. Genetic screening and risk assessment in hypertrophic cardiomyopathy. J Am Coll Cardiol. 2004 Dec 21; 44(12):2326-8.
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  112. Ellinor PT, Moore RK, Patton KK, Ruskin JN, Pollak MR, Macrae CA. Mutations in the long QT gene, KCNQ1, are an uncommon cause of atrial fibrillation. Heart. 2004 Dec; 90(12):1487-8.
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  113. Gerull B, Heuser A, Wichter T, Paul M, Basson CT, McDermott DA, Lerman BB, Markowitz SM, Ellinor PT, MacRae CA, Peters S, Grossmann KS, Drenckhahn J, Michely B, Sasse-Klaassen S, Birchmeier W, Dietz R, Breithardt G, Schulze-Bahr E, Thierfelder L. Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy. Nat Genet. 2004 Nov; 36(11):1162-4.
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  114. Friedrich EB, Liu E, Sinha S, Cook S, Milstone DS, MacRae CA, Mariotti M, Kuhlencordt PJ, Force T, Rosenzweig A, St-Arnaud R, Dedhar S, Gerszten RE. Integrin-linked kinase regulates endothelial cell survival and vascular development. Mol Cell Biol. 2004 Sep; 24(18):8134-44.
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  115. Peterson RT, Shaw SY, Peterson TA, Milan DJ, Zhong TP, Schreiber SL, MacRae CA, Fishman MC. Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation. Nat Biotechnol. 2004 May; 22(5):595-9.
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  116. CA MacRae and PT Ellinor . Genetic Diagnosis and Risk Stratification in HCM. JACC. 2004; (in press).
  117. MacRae CA, Peterson RT. Zebrafish-based small molecule discovery. Chem Biol. 2003 Oct; 10(10):901-8.
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  118. Ellinor PT, Macrae CA. The genetics of atrial fibrillation. J Cardiovasc Electrophysiol. 2003 Sep; 14(9):1007-9.
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  119. Ellinor PT, Milan DJ, MacRae CA. Risk stratification in the long-QT syndrome. N Engl J Med. 2003 Aug 28; 349(9):908-9; author reply 908-9.
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  120. Wang TJ, Nam BH, D'Agostino RB, Wolf PA, Lloyd-Jones DM, MacRae CA, Wilson PW, Polak JF, O'Donnell CJ. Carotid intima-media thickness is associated with premature parental coronary heart disease: the Framingham Heart Study. Circulation. 2003 Aug 5; 108(5):572-6.
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  121. Ellinor PT, Shin JT, Moore RK, Yoerger DM, MacRae CA. Locus for atrial fibrillation maps to chromosome 6q14-16. Circulation. 2003 Jun 17; 107(23):2880-3.
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  122. Tawakol A, Sims K, MacRae C, Friedman JR, Alpert NM, Fischman AJ, Gewirtz H. Myocardial flow regulation in people with mitochondrial myopathy, encephalopathy, lactic acidosis, stroke-like episodes/myoclonic epilepsy and ragged red fibers and other mitochondrial syndromes. Coron Artery Dis. 2003 May; 14(3):197-205.
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  123. Milan DJ, Peterson TA, Ruskin JN, Peterson RT, MacRae CA. Drugs that induce repolarization abnormalities cause bradycardia in zebrafish. Circulation. 2003 Mar 18; 107(10):1355-8.
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  124. CA MacRae and MC Fishman. Zebrafish-The Complete Cardiovascular Compendium. Symposium 67: The Cardiovascular System. 2003.
  125. CA MacRae and MC Fishman. Model Organisms for Cardiovascular Disease Gene Discovery. In KR Chien and CE Seidman, editors. The Molecular Basis of Cardiovascular Disease. 2003; 39-47.
  126. Hajjar RJ, MacRae CA. Adrenergic-receptor polymorphisms and heart failure. N Engl J Med. 2002 Oct 10; 347(15):1196-9.
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  127. RJ Hajjar and CA MacRae. a/b Adrenoreceptor Polymorphisms in Heart Failure. New England Journal of Medicine. 2002; 347:1196-1199.
  128. MacRae CA, Fishman MC. Zebrafish: the complete cardiovascular compendium. Cold Spring Harb Symp Quant Biol. 2002; 67:301-7.
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  129. PT Ellinor, DM Yoerger, BM McGovern, JN Ruskin, CA MacRae . Familial aggregation of atrial fibrillation. Finalist, American Heart Association, Council on Clinical Cardiology, Samuel A. Levine Young Clinical Investigator Award. Circulation. 2002; 106:I-12.
  130. MacRae CA. Genetics and dilated cardiomyopathy: limitations of candidate gene strategies. Eur Heart J. 2000 Nov; 21(22):1817-9.
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  131. Schönberger J, Levy H, Grünig E, Sangwatanaroj S, Fatkin D, MacRae C, Stäcker H, Halpin C, Eavey R, Philbin EF, Katus H, Seidman JG, Seidman CE. Dilated cardiomyopathy and sensorineural hearing loss: a heritable syndrome that maps to 6q23-24. Circulation. 2000 Apr 18; 101(15):1812-8.
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  132. Fatkin D, MacRae C, Sasaki T, Wolff MR, Porcu M, Frenneaux M, Atherton J, Vidaillet HJ, Spudich S, De Girolami U, Seidman JG, Seidman C, Muntoni F, Müehle G, Johnson W, McDonough B. Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease. N Engl J Med. 1999 Dec 2; 341(23):1715-24.
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  133. Mehdirad AA, Fatkin D, DiMarco JP, MacRae CA, Wase A, Seidman JG, Seidman CE, Benson DW. Electrophysiologic characteristics of accessory atrioventricular connections in an inherited form of Wolff-Parkinson-White syndrome. J Cardiovasc Electrophysiol. 1999 May; 10(5):629-35.
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  134. Siu BL, Niimura H, Osborne JA, Fatkin D, MacRae C, Solomon S, Benson DW, Seidman JG, Seidman CE. Familial dilated cardiomyopathy locus maps to chromosome 2q31. Circulation. 1999 Mar 2; 99(8):1022-6.
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  135. CE Seidman, CA MacRae, JG Seidman. Inherited cardiomyopathies. Principles of Molecular Medicine. 1998; 225-248.
  136. MacRae CA. Familial atrial fibrillation. N Engl J Med. 1997 Jul 31; 337(5):350.
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  137. Basson CT, MacRae CA, Korf B, Merliss A. Genetic heterogeneity of familial atrial myxoma syndromes (Carney complex). Am J Cardiol. 1997 Apr 1; 79(7):994-5.
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  138. Benson DW, Basson CT, MacRae CA. New understandings in the genetics of congenital heart disease. Curr Opin Pediatr. 1996 Oct; 8(5):505-11.
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  139. Basson CT, MacRae CA, Schoenberg-Fejzo M, Morton CC, Spinner NB, Genin A, Krug E, Seidman JG, Seidman CE. Identification, characterization, and chromosomal localization of the human homolog (hES) of ES/130. Genomics. 1996 Aug 1; 35(3):628-31.
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  140. Manolis EN, Yandavi N, Nadol JB, Eavey RD, McKenna M, Rosenbaum S, Khetarpal U, Halpin C, Merchant SN, Duyk GM, MacRae C, Seidman CE, Seidman JG. A gene for non-syndromic autosomal dominant progressive postlingual sensorineural hearing loss maps to chromosome 14q12-13. Hum Mol Genet. 1996 Jul; 5(7):1047-50.
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  141. Benson DW, MacRae CA, Vesely MR, Walsh EP, Seidman JG, Seidman CE, Satler CA. Missense mutation in the pore region of HERG causes familial long QT syndrome. Circulation. 1996 May 15; 93(10):1791-5.
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  142. CA MacRae . The genetics of hypertrophic cardiomyopathy. Advances in Cardiology. In R. Gorlin and P.K. Toutouzas, editors. 1996; 1-16.
  143. JA Osborne, CA MacRae, DW Benson, S Solomon, JG Seidman, CE Seidman . Multiple genetic loci contribute to familial dilated cardiomyopathy. Circulation. 1996; 94:I-262.
  144. Watkins H, Conner D, Thierfelder L, Jarcho JA, MacRae C, McKenna WJ, Maron BJ, Seidman JG, Seidman CE. Mutations in the cardiac myosin binding protein-C gene on chromosome 11 cause familial hypertrophic cardiomyopathy. Nat Genet. 1995 Dec; 11(4):434-7.
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  145. MacRae CA, Ghaisas N, Kass S, Donnelly S, Basson CT, Watkins HC, Anan R, Thierfelder LH, McGarry K, Rowland E, et al. Familial Hypertrophic cardiomyopathy with Wolff-Parkinson-White syndrome maps to a locus on chromosome 7q3. J Clin Invest. 1995 Sep; 96(3):1216-20.
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  146. Basson CT, Solomon SD, Weissman B, MacRae CA, Poznanski AK, Prieto F, Ruiz de la Fuente S, Pease WE, Levin SE, Holmes LB, et al. Genetic heterogeneity of heart-hand syndromes. Circulation. 1995 Mar 1; 91(5):1326-9.
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  147. Wilton SD, Eyre H, Akkari PA, Watkins HC, MacRae C, Laing NG, Callen DC. Assignment of the human a-tropomyosin gene TPM3 to 1q22-->q23 by fluorescence in situ hybridisation. Cytogenet Cell Genet. 1995; 68(1-2):122-4.
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  148. CA MacRae, R Anan, D Harris, P Keeling, H Vidaillet, S Kubo, H Skirton, M James, J Burgess, WJ McKenna, S Mohiudin, JG Seidman, CE Seidman . Familial dilated cardiomyopathy with conduction disease exhibits both genetic and phenotypic heterogeneity. Circulation. 1995; 92:I-83.
  149. Watkins H, MacRae CA, Fischman DA, Seidman JG, Seidman CE. A dinucleotide repeat polymorphism in the MYBPH gene. Hum Mol Genet. 1994 Dec; 3(12):2267.
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  150. Kass S, MacRae C, Graber HL, Sparks EA, McNamara D, Boudoulas H, Basson CT, Baker PB, Cody RJ, Fishman MC, et al. A gene defect that causes conduction system disease and dilated cardiomyopathy maps to chromosome 1p1-1q1. Nat Genet. 1994 Aug; 7(4):546-51.
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  151. Thierfelder L, Watkins H, MacRae C, Lamas R, McKenna W, Vosberg HP, Seidman JG, Seidman CE. Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere. Cell. 1994 Jun 3; 77(5):701-12.
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  152. H Watkins, CA MacRae, LH Thierfelder, WJ McKenna, JG Seidman, CE Seidman . Mode of action of cardiac troponin T mutations in familial hypertrophic cardiomyopathy. Circulation. 1994; 90:I-520.
  153. MacRae CA, Watkins HC, Jarcho JA, Thierfelder L, McKenna WJ, Seidman JG, Seidman CE. An evaluation of ribonuclease protection assays for the detection of beta-cardiac myosin heavy chain gene mutations. Circulation. 1994 Jan; 89(1):33-5.
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  154. CA MacRae, HC Watkins, WJ McKenna Proc. . The genetics of hypertrophic cardiomyopathy. Royal Coll Phys Edin. 1994; 24:305-310.
  155. H Watkins, CA MacRae, LH Thierfelder, WJ McKenna, JG Seidman , CE Seidman . Clinical implications of cardiac troponin T mutations that cause familial hypertrophic cardiomyopathy. Circulation. 1994; 90:I-442.
  156. Thierfelder L, MacRae C, Watkins H, Tomfohrde J, Williams M, McKenna W, Bohm K, Noeske G, Schlepper M, Bowcock A, et al. A familial hypertrophic cardiomyopathy locus maps to chromosome 15q2. Proc Natl Acad Sci U S A. 1993 Jul 1; 90(13):6270-4.
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  157. Watkins HC, MacRae CA, Thierfelder L, McKenna WJ, Seidman CE, Seidman JG. A dinucleotide repeat polymorphism in the human LAMB2 gene on chromosome 1q. Hum Mol Genet. 1993 Jul; 2(7):1084.
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  158. Watkins H, MacRae C, Thierfelder L, Chou YH, Frenneaux M, McKenna W, Seidman JG, Seidman CE. A disease locus for familial hypertrophic cardiomyopathy maps to chromosome 1q3. Nat Genet. 1993 Apr; 3(4):333-7.
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  159. H Watkins, L Thierfelder, R Anan, CA MacRae, WJ McKenna, JG Seidman and CE Seidman . Independent origin of myosin mutations in hypertrophic cardiomyopathy. Eur Heart J. 1993; 14:(abstract suppl):1..
  160. MacRae CA, Marber MS, Keywood C, Joy M. Need for invasive cardiological assessment and intervention: a ten year review. Br Heart J. 1992 Feb; 67(2):200-3.
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  161. CA MacRae, C Lijia, MA DeBelder, DE Ward, CW Pumphrey, JC Kaski . Highly localised nitrate resistant coronary constriction occurs in humans immediately after percutaneous transluminal angioplasty. Circulation. 1992; 86:I-846.
  162. CA MacRae, IA Simpson, JF Sneddon, S Gibson, AJ Camm . Dobutamine is the most physiological stress for echocardiographic regional wall motion studies in multivessel coronary artery disease. Br Heart J. 1992; 67:120.
  163. M Hossein-Nia, P Brown, CF Shakespeare, CA MacRae, A O'Donoghue, DW Holt . Subclinical myocardial damage revealed by CK-MB2 isoform release in hypertrophic cardiomyopathy. Circulation. 1992; 86:I-592.
  164. Watkins H, Seidman CE, MacRae C, Seidman JG, McKenna W. Progress in familial hypertrophic cardiomyopathy: molecular genetic analyses in the original family studied by Teare. Br Heart J. 1992 Jan; 67(1):34-8.
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  165. Marber M, MacRae C, Joy M. Delay to invasive investigation and revascularisation for coronary heart disease in south west Thames region: a two tier system? BMJ. 1991 May 18; 302(6786):1189-91.
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  166. D Bell, M Jackson, CA MacRae, J Dawes, AL Muir . Neutrophil elastase: a marker of neutrophil activation in acute myocardial infarction?. Clinical Science. 1988; 72(S16):87.
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