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Douglas P. Kiel, M.D.

TitleProfessor of Medicine
InstitutionHebrew Rehabilitation Center
DepartmentMedicine
AddressHebrew Rehab Center For the Aged
Institute for Aging Research
1200 Centre St
Roslindale MA 02131
Phone617/971-5373
Fax617/971-5339
vCardDownload vCard (login for email)

 Biography 
 awards and honors
1972 - Phi Eta Sigma Honorary Sority
1975 - Magna Cum Laude
1981 - Alpha Omega Alpha
1989 - Fellow
1989 - Fellow
1990 - 1990Faculty Scholar in General Internal Medicine
1990 - Henry J. Kaiser Family Foundation Faculty Scholar in General Internal Medicine
1994 - 1996NIH Ad Hoc Reviewer Epidemiology and Disease Control-2, NRRC, and Geriatrics & Rehab Study Sections
1997 - 1997Invited Peer Reviewer
1999 - 2000Invited Contributor
2002 - 2002Ad Hoc Reviewer
2002 - 2002Invited Presenter
2003 - 2003Ad Hoc Reviewer
2003 - Education Committee Member
2003 - 2003Invited Participant
2003 - Invited Safety Officer
2004 - Excellence in Mentoring Award Nominee
2004 - Excellence in Mentoring Award, nominee
2004 - Invited Contributor
2004 - Nominated for Excellence in Mentoring Award, nominee
2005 - Outstanding Excellence in Geriatric Research All Categories
2007 - Annual Center for Faculty Development Membership Award for Excellence Mentoring
2007 - Nominated for Excellence in Mentoring Award
2008 - 2011Appointment to NIA Clinical Trials Advisory Panel
2008 - Elected to Council
2010 - 2011Clifford Barger Excellence in Mentoring Award
2010 - 2011Chair Skin, Bone, Muscle and Joint Working Group
2013 - Fellow of the American Geriatrics Society
2013 - Fellow of the Gerontological Society of America

 Mentoring 
 current student opportunities
Available: 09/01/14, Expires: 08/31/15

Using existing skeletal imaging data from the Framingham Osteoporosis Study, the student will work with a team of investigators to identify lifestyle and genetic factors related to bone microarchitecture.

The Framingham Osteoporosis Study is collecting high resolution peripheral quantitative computed tomography (HR-pQCT) scans on members of the Framingham Study Offspring cohort. These scans provide measurements of volumetric bone density of cortical and trabecular compartments, microarchitecture, including cortical porosity, and can be used to derive micro finite element analysis. Thus there are many measures which provide unique insights into bone strength that are not available using any other technique. The student will learn about the imaging technique itself and then will actually perform data analyses to relate lifestyle and genetic factors to these measures. This will lead to one or more publications in peer review journals. Some prior knowledge of biomechanical engineering principles and/or statistical data analysis would be useful background skills, as would experience with scientific writing.


 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Berry SD, McLean RR, Hannan MT, Cupples LA, Kiel DP. Changes in bone mineral density may predict the risk of fracture differently in older adults according to fall history. J Am Geriatr Soc. 2014 Dec; 62(12):2345-9.
    View in: PubMed
  2. Broer L, Buchman AS, Deelen J, Evans DS, Faul JD, Lunetta KL, Sebastiani P, Smith JA, Smith AV, Tanaka T, Yu L, Arnold AM, Aspelund T, Benjamin EJ, De Jager PL, Eirkisdottir G, Evans DA, Garcia ME, Hofman A, Kaplan RC, Kardia SL, Kiel DP, Oostra BA, Orwoll ES, Parimi N, Psaty BM, Rivadeneira F, Rotter JI, Seshadri S, Singleton A, Tiemeier H, Uitterlinden AG, Zhao W, Bandinelli S, Bennett DA, Ferrucci L, Gudnason V, Harris TB, Karasik D, Launer LJ, Perls TT, Slagboom PE, Tranah GJ, Weir DR, Newman AB, van Duijn CM, Murabito JM. GWAS of Longevity in CHARGE Consortium Confirms APOE and FOXO3 Candidacy. J Gerontol A Biol Sci Med Sci. 2015 Jan; 70(1):110-8.
    View in: PubMed
  3. Sahni S, Mangano KM, Tucker KL, Kiel DP, Casey VA, Hannan MT. Protective association of milk intake on the risk of hip fracture: results from the framingham original cohort. J Bone Miner Res. 2014 Aug; 29(8):1756-62.
    View in: PubMed
  4. Sponholtz TR, Zhang X, Fontes JD, Meigs JB, Cupples LA, Kiel DP, Hannan MT, McLean RR. Association between inflammatory biomarkers and bone mineral density in a community-based cohort of men and women. Arthritis Care Res (Hoboken). 2014 Aug; 66(8):1233-40.
    View in: PubMed
  5. Kwan JS, Hsu YH, Cheung CL, Dupuis J, Saint-Pierre A, Eriksson J, Handelman SK, Aragaki A, Karasik D, Pramstaller PP, Kooperberg C, Lacroix AZ, Larson MG, Lau KS, Lorentzon M, Pichler I, Sham PC, Taliun D, Vandenput L, Kiel DP, Hicks AA, Jackson RD, Ohlsson C, Benjamin EJ, Kung AW. Meta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels. Hum Mol Genet. 2014 Dec 15; 23(24):6684-93.
    View in: PubMed
  6. Perry JR, Day F, Elks CE, Sulem P, Thompson DJ, Ferreira T, He C, Chasman DI, Esko T, Thorleifsson G, Albrecht E, Ang WQ, Corre T, Cousminer DL, Feenstra B, Franceschini N, Ganna A, Johnson AD, Kjellqvist S, Lunetta KL, McMahon G, Nolte IM, Paternoster L, Porcu E, Smith AV, Stolk L, Teumer A, Tšernikova N, Tikkanen E, Ulivi S, Wagner EK, Amin N, Bierut LJ, Byrne EM, Hottenga JJ, Koller DL, Mangino M, Pers TH, Yerges-Armstrong LM, Hua Zhao J, Andrulis IL, Anton-Culver H, Atsma F, Bandinelli S, Beckmann MW, Benitez J, Blomqvist C, Bojesen SE, Bolla MK, Bonanni B, Brauch H, Brenner H, Buring JE, Chang-Claude J, Chanock S, Chen J, Chenevix-Trench G, Collée JM, Couch FJ, Couper D, Coviello AD, Cox A, Czene K, D'adamo AP, Davey Smith G, De Vivo I, Demerath EW, Dennis J, Devilee P, Dieffenbach AK, Dunning AM, Eiriksdottir G, Eriksson JG, Fasching PA, Ferrucci L, Flesch-Janys D, Flyger H, Foroud T, Franke L, Garcia ME, García-Closas M, Geller F, de Geus EE, Giles GG, Gudbjartsson DF, Gudnason V, Guénel P, Guo S, Hall P, Hamann U, Haring R, Hartman CA, Heath AC, Hofman A, Hooning MJ, Hopper JL, Hu FB, Hunter DJ, Karasik D, Kiel DP, Knight JA, Kosma VM, Kutalik Z, Lai S, Lambrechts D, Lindblom A, Mägi R, Magnusson PK, Mannermaa A, Martin NG, Masson G, McArdle PF, McArdle WL, Melbye M, Michailidou K, Mihailov E, Milani L, Milne RL, Nevanlinna H, Neven P, Nohr EA, Oldehinkel AJ, Oostra BA, Palotie A, Peacock M, Pedersen NL, Peterlongo P, Peto J, Pharoah PD, Postma DS, Pouta A, Pylkäs K, Radice P, Ring S, Rivadeneira F, Robino A, Rose LM, Rudolph A, Salomaa V, Sanna S, Schlessinger D, Schmidt MK, Southey MC, Sovio U, Stampfer MJ, Stöckl D, Storniolo AM, Timpson NJ, Tyrer J, Visser JA, Vollenweider P, Völzke H, Waeber G, Waldenberger M, Wallaschofski H, Wang Q, Willemsen G, Winqvist R, Wolffenbuttel BH, Wright MJ, Boomsma DI, Econs MJ, Khaw KT, Loos RJ, McCarthy MI, Montgomery GW, Rice JP, Streeten EA, Thorsteinsdottir U, van Duijn CM, Alizadeh BZ, Bergmann S, Boerwinkle E, Boyd HA, Crisponi L, Gasparini P, Gieger C, Harris TB, Ingelsson E, Järvelin MR, Kraft P, Lawlor D, Metspalu A, Pennell CE, Ridker PM, Snieder H, Sørensen TI, Spector TD, Strachan DP, Uitterlinden AG, Wareham NJ, Widen E, Zygmunt M, Murray A, Easton DF, Stefansson K, Murabito JM, Ong KK. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature. 2014 Oct 2; 514(7520):92-7.
    View in: PubMed
  7. Huang J, Hsu YH, Mo C, Abreu E, Kiel DP, Bonewald LF, Brotto M, Karasik D. METTL21C Is a Potential Pleiotropic Gene for Osteoporosis and Sarcopenia Acting Through the Modulation of the NF-?B Signaling Pathway. J Bone Miner Res. 2014 Jul; 29(7):1531-40.
    View in: PubMed
  8. Studenski SA, Peters KW, Alley DE, Cawthon PM, McLean RR, Harris TB, Ferrucci L, Guralnik JM, Fragala MS, Kenny AM, Kiel DP, Kritchevsky SB, Shardell MD, Dam TT, Vassileva MT. The FNIH Sarcopenia Project: Rationale, Study Description, Conference Recommendations, and Final Estimates. J Gerontol A Biol Sci Med Sci. 2014 May; 69(5):547-58.
    View in: PubMed
  9. Cawthon PM, Peters KW, Shardell MD, McLean RR, Dam TT, Kenny AM, Fragala MS, Harris TB, Kiel DP, Guralnik JM, Ferrucci L, Kritchevsky SB, Vassileva MT, Studenski SA, Alley DE. Cutpoints for low appendicular lean mass that identify older adults with clinically significant weakness. J Gerontol A Biol Sci Med Sci. 2014 May; 69(5):567-75.
    View in: PubMed
  10. McLean RR, Shardell MD, Alley DE, Cawthon PM, Fragala MS, Harris TB, Kenny AM, Peters KW, Ferrucci L, Guralnik JM, Kritchevsky SB, Kiel DP, Vassileva MT, Xue QL, Perera S, Studenski SA, Dam TT. Criteria for Clinically Relevant Weakness and Low Lean Mass and Their Longitudinal Association With Incident Mobility Impairment and Mortality: The Foundation for the National Institutes of Health (FNIH) Sarcopenia Project. J Gerontol A Biol Sci Med Sci. 2014 May; 69(5):576-83.
    View in: PubMed
  11. Dam TT, Peters KW, Fragala M, Cawthon PM, Harris TB, McLean R, Shardell M, Alley DE, Kenny A, Ferrucci L, Guralnik J, Kiel DP, Kritchevsky S, Vassileva MT, Studenski S. An evidence-based comparison of operational criteria for the presence of sarcopenia. J Gerontol A Biol Sci Med Sci. 2014 May; 69(5):584-90.
    View in: PubMed
  12. Dufour AB, Roberts B, Broe KE, Kiel DP, Bouxsein ML, Hannan MT. Erratum to: The factor-of-risk biomechanical approach predicts hip fracture in men and women: the Framingham Study. Osteoporos Int. 2014 May; 25(5):1657.
    View in: PubMed
  13. Alley DE, Shardell MD, Peters KW, McLean RR, Dam TT, Kenny AM, Fragala MS, Harris TB, Kiel DP, Guralnik JM, Ferrucci L, Kritchevsky SB, Studenski SA, Vassileva MT, Cawthon PM. Grip strength cutpoints for the identification of clinically relevant weakness. J Gerontol A Biol Sci Med Sci. 2014 May; 69(5):559-66.
    View in: PubMed
  14. Berry SD, Kiel DP. Treating hypertension in the elderly: should the risk of falls be part of the equation? JAMA Intern Med. 2014 Apr 1; 174(4):596-7.
    View in: PubMed
  15. Misra D, Zhang Y, Peloquin C, Choi HK, Kiel DP, Neogi T. Incident long-term warfarin use and risk of osteoporotic fractures: propensity-score matched cohort of elders with new onset atrial fibrillation. Osteoporos Int. 2014 Jun; 25(6):1677-84.
    View in: PubMed
  16. Lewiecki EM, Bilezikian JP, Bonewald L, Compston JE, Heaney RP, Kiel DP, Miller PD, Schousboe JT. Osteoporosis update: proceedings of the 2013 Santa Fe Bone Symposium. J Clin Densitom. 2014 Jul-Sep; 17(3):330-43.
    View in: PubMed
  17. Bruno AG, Broe KE, Zhang X, Samelson EJ, Meng CA, Manoharan R, D'Agostino J, Cupples LA, Kiel DP, Bouxsein ML. Vertebral Size, Bone Density, and Strength in Men and Women Matched for Age and Areal Spine BMD. J Bone Miner Res. 2014 Mar; 29(3):562-9.
    View in: PubMed
  18. Oei L, Estrada K, Duncan EL, Christiansen C, Liu CT, Langdahl BL, Obermayer-Pietsch B, Riancho JA, Prince RL, van Schoor NM, McCloskey E, Hsu YH, Evangelou E, Ntzani E, Evans DM, Alonso N, Husted LB, Valero C, Hernandez JL, Lewis JR, Kaptoge SK, Zhu K, Cupples LA, Medina-Gómez C, Vandenput L, Kim GS, Hun Lee S, Castaño-Betancourt MC, Oei EH, Martinez J, Daroszewska A, van der Klift M, Mellström D, Herrera L, Karlsson MK, Hofman A, Ljunggren Ö, Pols HA, Stolk L, van Meurs JB, Ioannidis JP, Zillikens MC, Lips P, Karasik D, Uitterlinden AG, Styrkarsdottir U, Brown MA, Koh JM, Richards JB, Reeve J, Ohlsson C, Ralston SH, Kiel DP, Rivadeneira F. Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus. Bone. 2014 Feb; 59:20-7.
    View in: PubMed
  19. Roux C, Binkley N, Boonen S, Kiel DP, Ralston SH, Reginster JY, Pong A, Rosenberg E, Santora A. Erratum to: Vitamin D Status and Bone Mineral Density Changes During Alendronate Treatment in Postmenopausal Osteoporosis. Calcif Tissue Int. 2014 Feb; 94(2):158.
    View in: PubMed
  20. Samelson EJ, Miller PD, Christiansen C, Daizadeh NS, Grazette L, Anthony MS, Egbuna O, Wang A, Siddhanti SR, Cheung AM, Franchimont N, Kiel DP. RANKL Inhibition With Denosumab Does Not Influence 3-Year Progression of Aortic Calcification or Incidence of Adverse Cardiovascular Events in Postmenopausal Women With Osteoporosis and High Cardiovascular Risk. J Bone Miner Res. 2014 Feb; 29(2):450-7.
    View in: PubMed
  21. Moayyeri A, Hsu YH, Karasik D, Estrada K, Xiao SM, Nielson C, Srikanth P, Giroux S, Wilson SG, Zheng HF, Smith AV, Pye SR, Leo PJ, Teumer A, Hwang JY, Ohlsson C, McGuigan F, Minster RL, Hayward C, Olmos JM, Lyytikäinen LP, Lewis JR, Swart KM, Masi L, Oldmeadow C, Holliday EG, Cheng S, van Schoor NM, Harvey NC, Kruk M, Del Greco M F, Igl W, Trummer O, Grigoriou E, Luben R, Liu CT, Zhou Y, Oei L, Medina-Gomez C, Zmuda J, Tranah G, Brown SJ, Williams FM, Soranzo N, Jakobsdottir J, Siggeirsdottir K, Holliday KL, Hannemann A, Go MJ, Garcia M, Polasek O, Laaksonen M, Zhu K, Enneman AW, McEvoy M, Peel R, Sham PC, Jaworski M, Johansson A, Hicks AA, Pludowski P, Scott R, Dhonukshe-Rutten RA, van der Velde N, Kähönen M, Viikari JS, Sievänen H, Raitakari OT, González-Macías J, Hernández JL, Mellström D, Ljunggren O, Cho YS, Völker U, Nauck M, Homuth G, Völzke H, Haring R, Brown MA, McCloskey E, Nicholson GC, Eastell R, Eisman JA, Jones G, Reid IR, Dennison EM, Wark J, Boonen S, Vanderschueren D, Wu FC, Aspelund T, Richards JB, Bauer D, Hofman A, Khaw KT, Dedoussis G, Obermayer-Pietsch B, Gyllensten U, Pramstaller PP, Lorenc RS, Cooper C, Kung AW, Lips P, Alen M, Attia J, Brandi ML, de Groot LC, Lehtimäki T, Riancho JA, Campbell H, Liu Y, Harris TB, Akesson K, Karlsson M, Lee JY, Wallaschofski H, Duncan EL, O'Neill TW, Gudnason V, Spector TD, Rousseau F, Orwoll E, Cummings SR, Wareham NJ, Rivadeneira F, Uitterlinden AG, Prince RL, Kiel DP, Reeve J, Kaptoge SK. Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. Hum Mol Genet. 2014 Jun 1; 23(11):3054-68.
    View in: PubMed
  22. Oei L, Hsu YH, Styrkarsdottir U, Eussen BH, de Klein A, Peters MJ, Halldorsson B, Liu CT, Alonso N, Kaptoge SK, Thorleifsson G, Hallmans G, Hocking LJ, Husted LB, Jameson KA, Kruk M, Lewis JR, Patel MS, Scollen S, Svensson O, Trompet S, van Schoor NM, Zhu K, Buckley BM, Cooper C, Ford I, Goltzman D, González-Macías J, Langdahl BL, Leslie WD, Lips P, Lorenc RS, Olmos JM, Pettersson-Kymmer U, Reid DM, Riancho JA, Slagboom PE, Garcia-Ibarbia C, Ingvarsson T, Johannsdottir H, Luben R, Medina-Gómez C, Arp P, Nandakumar K, Palsson ST, Sigurdsson G, van Meurs JB, Zhou Y, Hofman A, Jukema JW, Pols HA, Prince RL, Cupples LA, Marshall CR, Pinto D, Sato D, Scherer SW, Reeve J, Thorsteinsdottir U, Karasik D, Richards JB, Stefansson K, Uitterlinden AG, Ralston SH, Ioannidis JP, Kiel DP, Rivadeneira F, Estrada K. A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus. J Med Genet. 2014 Feb; 51(2):122-31.
    View in: PubMed
  23. Sahni S, Tucker KL, Kiel DP, Quach L, Casey VA, Hannan MT. Erratum to: Milk and yogurt consumption are linked with higher bone mineral density but not with hip fracture: the Framingham Offspring Study. Arch Osteoporos. 2013 Dec; 8(1-2):132.
    View in: PubMed
  24. Eum R, Leveille SG, Kiely DK, Kiel DP, Samelson EJ, Bean JF. Is kyphosis related to mobility, balance, and disability? Am J Phys Med Rehabil. 2013 Nov; 92(11):980-9.
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  25. Sahni S, Broe KE, Tucker KL, McLean RR, Kiel DP, Cupples LA, Hannan MT. Association of total protein intake with bone mineral density and bone loss in men and women from the Framingham Offspring Study. Public Health Nutr. 2014 Nov; 17(11):2570-6.
    View in: PubMed
  26. Berry SD, Samelson EJ, Pencina MJ, McLean RR, Cupples LA, Broe KE, Kiel DP. Repeat bone mineral density screening and prediction of hip and major osteoporotic fracture. JAMA. 2013 Sep 25; 310(12):1256-62.
    View in: PubMed
  27. Bonewald LF, Kiel DP, Clemens TL, Esser K, Orwoll ES, O'Keefe RJ, Fielding RA. Forum on bone and skeletal muscle interactions: summary of the proceedings of an ASBMR workshop. J Bone Miner Res. 2013 Sep; 28(9):1857-65.
    View in: PubMed
  28. Anderson DE, Demissie S, Allaire BT, Bruno AG, Kopperdahl DL, Keaveny TM, Kiel DP, Bouxsein ML. The associations between QCT-based vertebral bone measurements and prevalent vertebral fractures depend on the spinal locations of both bone measurement and fracture. Osteoporos Int. 2014 Feb; 25(2):559-66.
    View in: PubMed
  29. Muir JW, Kiel DP, Hannan M, Magaziner J, Rubin CT. Dynamic parameters of balance which correlate to elderly persons with a history of falls. PLoS One. 2013; 8(8):e70566.
    View in: PubMed
  30. Roux C, Binkley N, Boonen S, Kiel DP, Ralston SH, Regnister JY, Pong A, Rosenberg E, Santora A. Vitamin d status and bone mineral density changes during alendronate treatment in postmenopausal osteoporosis. Calcif Tissue Int. 2014 Feb; 94(2):153-7.
    View in: PubMed
  31. van Meurs JB, Pare G, Schwartz SM, Hazra A, Tanaka T, Vermeulen SH, Cotlarciuc I, Yuan X, Mälarstig A, Bandinelli S, Bis JC, Blom H, Brown MJ, Chen C, Chen YD, Clarke RJ, Dehghan A, Erdmann J, Ferrucci L, Hamsten A, Hofman A, Hunter DJ, Goel A, Johnson AD, Kathiresan S, Kampman E, Kiel DP, Kiemeney LA, Chambers JC, Kraft P, Lindemans J, McKnight B, Nelson CP, O'Donnell CJ, Psaty BM, Ridker PM, Rivadeneira F, Rose LM, Seedorf U, Siscovick DS, Schunkert H, Selhub J, Ueland PM, Vollenweider P, Waeber G, Waterworth DM, Watkins H, Witteman JC, den Heijer M, Jacques P, Uitterlinden AG, Kooner JS, Rader DJ, Reilly MP, Mooser V, Chasman DI, Samani NJ, Ahmadi KR. Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. Am J Clin Nutr. 2013 Sep; 98(3):668-76.
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  32. DiGirolamo DJ, Kiel DP, Esser KA. Bone and skeletal muscle: neighbors with close ties. J Bone Miner Res. 2013 Jul; 28(7):1509-18.
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  33. Travison TG, Zhuang WV, Lunetta KL, Karasik D, Bhasin S, Kiel DP, Coviello AD, Murabito JM. The heritability of circulating testosterone, oestradiol, oestrone and sex hormone binding globulin concentrations in men: the Framingham Heart Study. Clin Endocrinol (Oxf). 2014 Feb; 80(2):277-82.
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  34. Muir J, Kiel DP, Rubin CT. Safety and severity of accelerations delivered from whole body vibration exercise devices to standing adults. J Sci Med Sport. 2013 Nov; 16(6):526-31.
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  35. Koller DL, Zheng HF, Karasik D, Yerges-Armstrong L, Liu CT, McGuigan F, Kemp JP, Giroux S, Lai D, Edenberg HJ, Peacock M, Czerwinski SA, Choh AC, McMahon G, St Pourcain B, Timpson NJ, Lawlor DA, Evans DM, Towne B, Blangero J, Carless MA, Kammerer C, Goltzman D, Kovacs CS, Prior JC, Spector TD, Rousseau F, Tobias JH, Akesson K, Econs MJ, Mitchell BD, Richards JB, Kiel DP, Foroud T. Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women. J Bone Miner Res. 2013 Mar; 28(3):547-58.
    View in: PubMed
  36. Sahni S, Tucker KL, Kiel DP, Quach L, Casey VA, Hannan MT. Milk and yogurt consumption are linked with higher bone mineral density but not with hip fracture: the Framingham Offspring Study. Arch Osteoporos. 2013; 8(1-2):119.
    View in: PubMed
  37. Nguyen US, Kiel DP, Li W, Galica AM, Kang HG, Casey VA, Hannan MT. Correlations of clinical and laboratory measures of balance in older men and women. Arthritis Care Res (Hoboken). 2012 Dec; 64(12):1895-902.
    View in: PubMed
  38. Jeffrey BA, Hannan MT, Quinn EK, Zimmerman S, Barton BA, Rubin CT, Kiel DP. Self-reported adherence with the use of a device in a clinical trial as validated by electronic monitors: the VIBES study. BMC Med Res Methodol. 2012; 12:171.
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  39. Samelson EJ, Booth SL, Fox CS, Tucker KL, Wang TJ, Hoffmann U, Cupples LA, O'Donnell CJ, Kiel DP. Calcium intake is not associated with increased coronary artery calcification: the Framingham Study. Am J Clin Nutr. 2012 Dec; 96(6):1274-80.
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  40. Liu CT, Estrada K, Yerges-Armstrong LM, Amin N, Evangelou E, Li G, Minster RL, Carless MA, Kammerer CM, Oei L, Zhou Y, Alonso N, Dailiana Z, Eriksson J, García-Giralt N, Giroux S, Husted LB, Khusainova RI, Koromila T, Kung AW, Lewis JR, Masi L, Mencej-Bedrac S, Nogues X, Patel MS, Prezelj J, Richards JB, Sham PC, Spector T, Vandenput L, Xiao SM, Zheng HF, Zhu K, Balcells S, Brandi ML, Frost M, Goltzman D, González-Macías J, Karlsson M, Khusnutdinova EK, Kollia P, Langdahl BL, Ljunggren O, Lorentzon M, Marc J, Mellström D, Ohlsson C, Olmos JM, Ralston SH, Riancho JA, Rousseau F, Urreizti R, Van Hul W, Zarrabeitia MT, Castano-Betancourt M, Demissie S, Grundberg E, Herrera L, Kwan T, Medina-Gómez C, Pastinen T, Sigurdsson G, Thorleifsson G, Vanmeurs JB, Blangero J, Hofman A, Liu Y, Mitchell BD, O'Connell JR, Oostra BA, Rotter JI, Stefansson K, Streeten EA, Styrkarsdottir U, Thorsteinsdottir U, Tylavsky FA, Uitterlinden A, Cauley JA, Harris TB, Ioannidis JP, Psaty BM, Robbins JA, Zillikens MC, Vanduijn CM, Prince RL, Karasik D, Rivadeneira F, Kiel DP, Cupples LA, Hsu YH. Assessment of gene-by-sex interaction effect on bone mineral density. J Bone Miner Res. 2012 Oct; 27(10):2051-64.
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  41. Hsu YH, Kiel DP. Clinical review: Genome-wide association studies of skeletal phenotypes: what we have learned and where we are headed. J Clin Endocrinol Metab. 2012 Oct; 97(10):E1958-77.
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  42. Anderson DE, D'Agostino JM, Bruno AG, Demissie S, Kiel DP, Bouxsein ML. Variations of CT-based trunk muscle attenuation by age, sex, and specific muscle. J Gerontol A Biol Sci Med Sci. 2013 Mar; 68(3):317-23.
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  43. Szulc P, Samelson EJ, Sornay-Rendu E, Chapurlat R, Kiel DP. Severity of aortic calcification is positively associated with vertebral fracture in older men--a densitometry study in the STRAMBO cohort. Osteoporos Int. 2013 Apr; 24(4):1177-84.
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  44. Coviello AD, Haring R, Wellons M, Vaidya D, Lehtimäki T, Keildson S, Lunetta KL, He C, Fornage M, Lagou V, Mangino M, Onland-Moret NC, Chen B, Eriksson J, Garcia M, Liu YM, Koster A, Lohman K, Lyytikäinen LP, Petersen AK, Prescott J, Stolk L, Vandenput L, Wood AR, Zhuang WV, Ruokonen A, Hartikainen AL, Pouta A, Bandinelli S, Biffar R, Brabant G, Cox DG, Chen Y, Cummings S, Ferrucci L, Gunter MJ, Hankinson SE, Martikainen H, Hofman A, Homuth G, Illig T, Jansson JO, Johnson AD, Karasik D, Karlsson M, Kettunen J, Kiel DP, Kraft P, Liu J, Ljunggren Ö, Lorentzon M, Maggio M, Markus MR, Mellström D, Miljkovic I, Mirel D, Nelson S, Morin Papunen L, Peeters PH, Prokopenko I, Raffel L, Reincke M, Reiner AP, Rexrode K, Rivadeneira F, Schwartz SM, Siscovick D, Soranzo N, Stöckl D, Tworoger S, Uitterlinden AG, van Gils CH, Vasan RS, Wichmann HE, Zhai G, Bhasin S, Bidlingmaier M, Chanock SJ, De Vivo I, Harris TB, Hunter DJ, Kähönen M, Liu S, Ouyang P, Spector TD, van der Schouw YT, Viikari J, Wallaschofski H, McCarthy MI, Frayling TM, Murray A, Franks S, Järvelin MR, de Jong FH, Raitakari O, Teumer A, Ohlsson C, Murabito JM, Perry JR. A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet. 2012; 8(7):e1002805.
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  45. Berry SD, Zhu Y, Choi H, Kiel DP, Zhang Y. Diuretic initiation and the acute risk of hip fracture. Osteoporos Int. 2013 Feb; 24(2):689-95.
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  276. Langlois JA, Rosen CJ, Visser M, Hannan MT, Harris T, Wilson PW, Kiel DP. Association between insulin-like growth factor I and bone mineral density in older women and men: the Framingham Heart Study. J Clin Endocrinol Metab. 1998 Dec; 83(12):4257-62.
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  277. Kauppila LI, Eustace S, Kiel DP, Felson DT, Wright AM. Degenerative displacement of lumbar vertebrae. A 25-year follow-up study in Framingham. Spine (Phila Pa 1976). 1998 Sep 1; 23(17):1868-73; discussion 1873-4.
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  278. Kiel DP, Puhl J, Rosen CJ, Berg K, Murphy JB, MacLean DB. Lack of an association between insulin-like growth factor-I and body composition, muscle strength, physical performance or self-reported mobility among older persons with functional limitations. J Am Geriatr Soc. 1998 Jul; 46(7):822-8.
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  279. Harris TB, Langlois JA, Kiel DP, Hannan MT, Roubenoff R. Re: "Epidemiology of insulin-like growth factor-I in elderly men and women. The Rancho Bernardo Study". Am J Epidemiol. 1998 Jun 1; 147(11):1093-4.
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  280. Greenspan SL, Myers ER, Kiel DP, Parker RA, Hayes WC, Resnick NM. Fall direction, bone mineral density, and function: risk factors for hip fracture in frail nursing home elderly. Am J Med. 1998 Jun; 104(6):539-45.
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  281. Visser M, Harris TB, Langlois J, Hannan MT, Roubenoff R, Felson DT, Wilson PW, Kiel DP. Body fat and skeletal muscle mass in relation to physical disability in very old men and women of the Framingham Heart Study. J Gerontol A Biol Sci Med Sci. 1998 May; 53(3):M214-21.
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  282. Kiely DK, Kiel DP, Burrows AB, Lipsitz LA. Identifying nursing home residents at risk for falling. J Am Geriatr Soc. 1998 May; 46(5):551-5.
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  283. Visser M, Kiel DP, Langlois J, Hannan MT, Felson DT, Wilson PW, Harris TB. Muscle mass and fat mass in relation to bone mineral density in very old men and women: the Framingham Heart Study. Appl Radiat Isot. 1998 May-Jun; 49(5-6):745-7.
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  284. O'Donnell CJ, Cupples LA, Kauppila LI, Kiel DP, Hannan MT, Polak JF, Wilson PWF. Risk factors associated with progression of lumbar aortic calcification. Circulation. 1998; 97:829.
  285. Krall EA, Dawson-Hughes B, Hannan MT, Kiel DP. Postmenopausal estrogen replacement and tooth retention. Compend Contin Educ Dent Suppl. 1998; (22):S17-22.
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  286. Visser M, Kiel DP, Haffner SM, Roubenoff R, Abad L, Wilson PWF, Harris TB. Past weight gain is associated to with lower plasma leptin concentrations: The Framingham Heart Study. FASEB. 1998.
  287. Fabiny AR, Kiel DP. Assessing and treating weight loss in nursing home patients. Clin Geriatr Med. 1997 Nov; 13(4):737-51.
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  288. Chen Z, Smith CW, Kiel D, Van Waes C. Metastatic variants derived following in vivo tumor progression of an in vitro transformed squamous cell carcinoma line acquire a differential growth advantage requiring tumor-host interaction. Clin Exp Metastasis. 1997 Sep; 15(5):527-37.
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  289. Kauppila LI, Polak JF, Cupples LA, Hannan MT, Kiel DP, Wilson PW. New indices to classify location, severity and progression of calcific lesions in the abdominal aorta: a 25-year follow-up study. Atherosclerosis. 1997 Jul 25; 132(2):245-50.
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  290. Kauppila LI, McAlindon T, Evans S, Wilson PW, Kiel D, Felson DT. Disc degeneration/back pain and calcification of the abdominal aorta. A 25-year follow-up study in Framingham. Spine (Phila Pa 1976). 1997 Jul 15; 22(14):1642-7; discussion 1648-9.
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  291. Kiel DP, Myers RH, Cupples LA, Kong XF, Zhu XH, Ordovas J, Schaefer EJ, Felson DT, Rush D, Wilson PW, Eisman JA, Holick MF. The BsmI vitamin D receptor restriction fragment length polymorphism (bb) influences the effect of calcium intake on bone mineral density. J Bone Miner Res. 1997 Jul; 12(7):1049-57.
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  292. Krall EA, Dawson-Hughes B, Hannan MT, Wilson PW, Kiel DP. Postmenopausal estrogen replacement and tooth retention. Am J Med. 1997 Jun; 102(6):536-42.
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  293. Rooks DS, Kiel DP, Parsons C, Hayes WC. Self-paced resistance training and walking exercise in community-dwelling older adults: effects on neuromotor performance. J Gerontol A Biol Sci Med Sci. 1997 May; 52(3):M161-8.
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  294. Roubenoff R, Baumgartner RN, Harris TB, Dallal GE, Hannan MT, Economos CD, Stauber PM, Wilson PW, Kiel DP. Application of bioelectrical impedance analysis to elderly populations. J Gerontol A Biol Sci Med Sci. 1997 May; 52(3):M129-36.
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  295. Zhang Y, Kiel DP, Kreger BE, Cupples LA, Ellison RC, Dorgan JF, Schatzkin A, Levy D, Felson DT. Bone mass and the risk of breast cancer among postmenopausal women. N Engl J Med. 1997 Feb 27; 336(9):611-7.
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  296. Harris TB, Kiel D, Roubenoff R, Langlois J, Hannan M, Havlik R, Wilson P. Association of insulin-like growth factor-I with body composition, weight history, and past health behaviors in the very old: the Framingham Heart Study. J Am Geriatr Soc. 1997 Feb; 45(2):133-9.
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  297. Fabiny AR, Kiely DK, Hannan MT, Kiel DP. Physical activity past and present: The relationship with bone mineral density. J Am Geriatr Society. 1997; 45:S6.
  298. Visser M, Kiel DP, Langlois J, Wilson PWF, Hannan MT, Harris T. Muscle loss in older men and women: Prevalence and predictors in the Framingham Heart Study. Experimental Biology 1997 Meeting. 1997.
  299. Rosenberg R, Gagnon M, Murphy-Gismondi P, Lock Ooi W, Kiel DP, Lipsitz LA. Factors influencing subject willingness to participate in clinical gerontologic research. Aging (Milano). 1996 Dec; 8(6):400-8.
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  300. Kiel D, Feinmark SJ. Phospholipase D activity regulates the binding of leukotriene B4 to human polymorphonuclear leukocytes. J Pharmacol Exp Ther. 1996 Aug; 278(2):645-53.
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  301. Mitchell SL, Kiely DK, Kiel DP, Lipsitz LA. The epidemiology, clinical characteristics, and natural history of older nursing home residents with a diagnosis of Parkinson's disease. J Am Geriatr Soc. 1996 Apr; 44(4):394-9.
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  302. Kiel, DP. Management of Age-Related Osteoporosis. Osteoporosis in Clinical Medicine: Principles and Practice. Rosen CJ (ed). 1996; 225-238.
  303. Kiel DP, Zhang Y, Hannan MT, Anderson JJ, Baron JA, Felson DT. The effect of smoking at different life stages on bone mineral density in elderly men and women. Osteoporos Int. 1996; 6(3):240-8.
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  304. Lipsitz, LA, Burrows A, Kiel DP. Falls. Quality Care in the Nursing Home. Morris JN, Lipsitz LA, Murphy K, Belleville-Taylor P (eds). 1996; 258-267.
  305. Kiel DP, Hannan MT, Genant HK, Li J, Felson DT. Risk factors for long-term cortical bone loss. J Bone Miner Res. 1996; 11 (Suppl 1):S364.
  306. Kiel DP, Cali CM. Age-related bone loss in very old institutionalized persons: A 2-year longitudinal study. J Am Geriatr Soc. 1996; 44:S14.
  307. Rosen CJ, MacLean D, Kiel DP. Growth hormone treatment for 'frail' elders increases bone turnover and decreases bone mass in a dose-dependent manner. 10th International Congress of Endocrinology. 1996.
  308. Cali CM, Kiel DP. An epidemiologic study of fall-related fractures among institutionalized older people. J Am Geriatr Soc. 1995 Dec; 43(12):1336-40.
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  309. Felson DT, Zhang Y, Hannan MT, Kannel WB, Kiel DP. Alcohol intake and bone mineral density in elderly men and women. The Framingham Study. Am J Epidemiol. 1995 Sep 1; 142(5):485-92.
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  310. Kiel DP, Mercier CA, Dawson-Hughes B, Cali C, Hannan MT, Anderson JJ. The effects of analytic software and scan analysis technique on the comparison of dual X-ray absorptiometry with dual photon absorptiometry of the hip in the elderly. J Bone Miner Res. 1995 Jul; 10(7):1130-6.
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  311. Moore AA, Dorros C, Kiel DP, O'Sullivan PS, Silliman RA. Preventive health attitudes and practices of elderly persons attending senior centers. R I Med. 1995 Apr; 78(4):115-7.
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  312. Kiel D. Assessing vertebral fractures. National Osteoporosis Foundation Working Group on Vertebral Fractures. J Bone Miner Res. 1995 Apr; 10(4):518-23.
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  313. Maclean D, Kiel DP, Rosen CJ. Low dose growth hormone for frail elders stimulates bone turnover in a dose-dependent manner. J Bone Miner Res. 1995; 10 (Suppl 1):S458.
  314. Chaisson CE, Kiel DP, Hannan MT, Sawin CT, Felson DT. Is there an association between serum TSH concentration and bone mineral density (BMD) in elderly women?. J Bone Miner Res. 1995; 10 (Suppl 1):S465.
  315. Kiel DP, Roubenoff R, Hannan MT, Harris TB, Felson DT. The association of peripheral WBC-derived interleukin-1 (IL-1), tumor necrosis factor (TNF), interleukin-6 (IL-6) with bone mineral density (BMD) in a large cohort study. J Bone Miner Res. 1995; 10 (Suppl 1):S466.
  316. Cali CM, Kiel DP. Aged-related bone loss in the "old" old: A longitudinal study of institutionalized elderly. J Bone Miner Res. 1995; 10 (Suppl 1):S467.
  317. Hannan MT, Anderson JJ, Kiel DP, Felson DT. Height loss in women as an indicator of subsequent incident hip fracture. J Bone Miner Res. 1995; 10 (Suppl 1):S465.
  318. Kiel, DP. Vitamin D, Calcium and Bone: Descriptive Epidemiology. Nutritional Assessment of Elderly Populations. Rosenberg IH (ed). 1995; 277-290.
  319. Kiel DP, Eichorn A, Intrator O, Silliman RA, Mor V. The outcomes of patients newly admitted to nursing homes after hip fracture. Am J Public Health. 1994 Aug; 84(8):1281-6.
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  320. Harris T, Roubenoff R, Kiel D, Langlois J, Havlik R, Wilson P. Diagnosis of growth hormone deficiency in adults. Lancet. 1994 Jun 25; 343(8913):1646.
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  321. Kiel DP. New strategies to prevent hip fracture. Hosp Pract (Off Ed). 1994 Feb 15; 29(2):47-54.
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  322. Chaisson CE, Zhang Y, Kiel DP, Hannan MT, Jacques PF, Rush D, Felson DT. The effects of vitamin D and calcium on bone mineral density in the elderly. J Bone Miner Res. 1994; 9 (Suppl 1):S329.
  323. Rosen CJ, Kiel DP, Maclean DB. Serum insulin-like growth factor-I and its relationship to bone mass in frail elders. J Bone Miner Res. 1994; 9 (Suppl 1):S388.
  324. Kiel DP, Hannan MT, Genant HK, Felson DT. Prevalence and incidence of vertebral fractures in the elderly: Initial results from the Framingham Study. J Bone Miner Res. 1994; 9 (Suppl 1):S129.
  325. Kiel DP, Felson DT, Hannan MT, Anderson JJ, Wilson PW. Caffeine and bone density loss. Epidemiology. 1993 Nov; 4(6):557.
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  326. Felson DT, Zhang Y, Hannan MT, Kiel DP, Wilson PW, Anderson JJ. The effect of postmenopausal estrogen therapy on bone density in elderly women. N Engl J Med. 1993 Oct 14; 329(16):1141-6.
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  327. Kiel DP. The evaluation of falls in the emergency department. Clin Geriatr Med. 1993 Aug; 9(3):591-9.
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  328. Greendale GA, Silverman SL, Hays RD, Cooper C, Spector T, Kiel D, Reuben DB. Health-related quality of life in osteoporosis clinical trials. The Osteoporosis Quality of Life Study Group. Calcif Tissue Int. 1993 Aug; 53(2):75-7.
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  329. Kiel DP, Cali C. Unintentional weight loss in the nursing home: Results from the Minimum Data Set. J Am Geriatr Soc. 1993; 41 (Suppl):SA11.
  330. Kiel, DP. Laboratory Evaulation of the Geriatric Patient in the Planning of a Rehabilitation Program. Geriatric Physical Therapy: Principles and Practice. Guccione AA (ed). 1993; 159-170.
  331. Kiel, DP. Falls in the Elderly. Clinics in Geriatric Medicine. Pousada L (ed). 1993; 9:591-599.
  332. Kiel DP, Cali C. Age-related bone loss in the old old: A study of institutionalized elderly. J Am Geriatr Soc. 1993; 41 (Suppl):SA13.
  333. Kiel DP, Baron JA, Anderson JJ, Hannan MT, Felson DT. Smoking eliminates the protective effect of oral estrogens on the risk for hip fracture among women. Ann Intern Med. 1992 May 1; 116(9):716-21.
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  334. Kiel DP, Hannan MT, Felson DT. Total body fat is associated with total body bone mineral content in postmenopausal women. J Bone Miner Res. 1992; 7 (Suppl 1):S322.
  335. Kiel DP, O'Sullivan PS, Ellis PJ, Wartman SA. Alumni perspectives comparing a general internal medicine program and a traditional medicine program. J Gen Intern Med. 1991 Nov-Dec; 6(6):544-52.
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  336. Kiel DP, O'Sullivan P, Teno JM, Mor V. Health care utilization and functional status in the aged following a fall. Med Care. 1991 Mar; 29(3):221-8.
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  337. Kiel DP. Falls. R I Med J. 1991 Feb; 74(2):75-9.
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  338. Felson DT, Sloutskis D, Anderson JJ, Anthony JM, Kiel DP. Thiazide diuretics and the risk of hip fracture. Results from the Framingham Study. JAMA. 1991 Jan 16; 265(3):370-3.
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  339. Linnel PW, Hermansen SE, Elias MF, Robbins M, Bling-you R, Kiel DP, and Rosen C. Quality of life in osteoporotic women. J Bone Miner Res. 1991; 6 (Suppl 1):S106.
  340. Kiel D, Zipkin RE, Feinmark SJ. Desensitization of the leukotriene B4 receptor by partial agonists. Adv Prostaglandin Thromboxane Leukot Res. 1991; 21A:403-6.
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  341. Teno J, Kiel DP, Mor V. Multiple stumbles: a risk factor for falls in community-dwelling elderly. A prospective study. J Am Geriatr Soc. 1990 Dec; 38(12):1321-5.
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  342. Berland B, Wachtel TJ, Kiel DP, O'Sullivan PS, Phillips E. Patient characteristics associated with the use of mechanical restraints. J Gen Intern Med. 1990 Nov-Dec; 5(6):480-5.
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  343. Kiel DP, Felson DT, Hannan MT, Anderson JJ, Wilson PW. Caffeine and the risk of hip fracture: the Framingham Study. Am J Epidemiol. 1990 Oct; 132(4):675-84.
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  344. Kiel DP, Teno J, and O'Sullivan P. Does a computerized balance platform validly and reliably measure balance in a manner acceptable to older persons?. American Geriatrics Society Annual Meeting. 1990.
  345. Kiel DP, Baron JA, Plymate SR, Chute CG. Sex hormones and lipoproteins in men. Am J Med. 1989 Jul; 87(1):35-9.
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  346. Felson DT, Anderson JJ, Hannan MT, Milton RC, Wilson PW, Kiel DP. Impaired vision and hip fracture. The Framingham Study. J Am Geriatr Soc. 1989 Jun; 37(6):495-500.
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  347. Teno J, and Kiel DP. Gait speed and computerized balance measurements among subjects with and without fear of falling. Clin Res. 1989; 37:786A.
  348. Koppelman MCS, Kiel DP, Maroni A, and Carlton E. Fasting spot and 24-hour urinary hydroxyproline in postmenopausal women. J Clin Endocrinol Metab. 1989.
  349. Felson DT, Kiel DP, Anderson JJ, Kannel WB. Alcohol consumption and hip fractures: the Framingham Study. Am J Epidemiol. 1988 Nov; 128(5):1102-10.
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  350. Kiel DP, Felson DT, Anderson JJ, Wilson PW, Moskowitz MA. Hip fracture and the use of estrogens in postmenopausal women. The Framingham Study. N Engl J Med. 1987 Nov 5; 317(19):1169-74.
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  351. Chute CG, Baron JA, Plymate SR, Kiel DP, Pavia AT, Lozner EC, O'Keefe T, MacDonald GJ. Sex hormones and coronary artery disease. Am J Med. 1987 Nov; 83(5):853-9.
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  352. Kiel DP, Moskowitz MA. The urinalysis: a critical appraisal. Med Clin North Am. 1987 Jul; 71(4):607-24.
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  353. Kiel DP. Oculopharyngeal muscular dystrophy as a cause of dysphagia in the elderly. J Am Geriatr Soc. 1986 Feb; 34(2):144-7.
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  354. Chute CG, Baron JA, Plymate SR, Kiel DP, and Pavia AT. Relationship of risk factors for coronary artery disease in men. Clin Res. 1985; 33:246A.
  355. Ishizaki H, Wheat RW, Kiel DP, Conant NF. Serological cross-reactivity among Sporothrix schenckii, Ceratocystis, Europhium, and Graphium species. Infect Immun. 1978 Aug; 21(2):585-93.
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