Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

Michael Joseph Young, PH.D.

TitleAssociate Professor of Ophthalmology
InstitutionSchepens Eye Research Institute
DepartmentOphthalmology
AddressSchepens Eye Research Inst.
20 Staniford St.
Boston MA 02114
Phone617/912-7419
Fax617/912-0101
vCardDownload vCard (login for email)

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Huang R, Baranov P, Lai K, Zhang X, Ge J, Young MJ. Functional and morphological analysis of the subretinal injection of human retinal progenitor cells under Cyclosporin A treatment. Mol Vis. 2014; 20:1271-80.
    View in: PubMed
  2. Baranov PY, Tucker BA, Young MJ. Low-oxygen culture conditions extend the multipotent properties of human retinal progenitor cells. Tissue Eng Part A. 2014 May; 20(9-10):1465-75.
    View in: PubMed
  3. Liu Y, Wang R, Zarembinski TI, Doty N, Jiang C, Regatieri C, Zhang X, Young MJ. The application of hyaluronic acid hydrogels to retinal progenitor cell transplantation. Tissue Eng Part A. 2013 Jan; 19(1-2):135-42.
    View in: PubMed
  4. Velez G, Weingarden AR, Tucker BA, Lei H, Kazlauskas A, Young MJ. Retinal Pigment Epithelium and Müller Progenitor Cell Interaction Increase Müller Progenitor Cell Expression of PDGFRa and Ability to Induce Proliferative Vitreoretinopathy in a Rabbit Model. Stem Cells Int. 2012; 2012:106486.
    View in: PubMed
  5. Ma J, Kabiel M, Tucker BA, Ge J, Young MJ. Combining chondroitinase ABC and growth factors promotes the integration of murine retinal progenitor cells transplanted into Rho(-/-) mice. Mol Vis. 2011; 17:1759-70.
    View in: PubMed
  6. Checa-Casalengua P, Jiang C, Bravo-Osuna I, Tucker BA, Molina-Martínez IT, Young MJ, Herrero-Vanrell R. Retinal ganglion cells survival in a glaucoma model by GDNF/Vit E PLGA microspheres prepared according to a novel microencapsulation procedure. J Control Release. 2011 Nov 30; 156(1):92-100.
    View in: PubMed
  7. Tucker BA, Park IH, Qi SD, Klassen HJ, Jiang C, Yao J, Redenti S, Daley GQ, Young MJ. Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice. PLoS One. 2011; 6(4):e18992.
    View in: PubMed
  8. Yao J, Tucker BA, Zhang X, Checa-Casalengua P, Herrero-Vanrell R, Young MJ. Robust cell integration from co-transplantation of biodegradable MMP2-PLGA microspheres with retinal progenitor cells. Biomaterials. 2011 Feb; 32(4):1041-50.
    View in: PubMed
  9. Sodha S, Wall K, Redenti S, Klassen H, Young MJ, Tao SL. Microfabrication of a three-dimensional polycaprolactone thin-film scaffold for retinal progenitor cell encapsulation. J Biomater Sci Polym Ed. 2011; 22(4-6):443-56.
    View in: PubMed
  10. Gu P, Yang J, Wang J, Young MJ, Klassen H. Sequential changes in the gene expression profile of murine retinal progenitor cells during the induction of differentiation. Mol Vis. 2009; 15:2111-22.
    View in: PubMed
  11. Tucker BA, Redenti SM, Jiang C, Swift JS, Klassen HJ, Smith ME, Wnek GE, Young MJ. The use of progenitor cell/biodegradable MMP2-PLGA polymer constructs to enhance cellular integration and retinal repopulation. Biomaterials. 2010 Jan; 31(1):9-19.
    View in: PubMed
  12. Tackenberg MA, Tucker BA, Swift JS, Jiang C, Redenti S, Greenberg KP, Flannery JG, Reichenbach A, Young MJ. Müller cell activation, proliferation and migration following laser injury. Mol Vis. 2009; 15:1886-96.
    View in: PubMed
  13. Redenti S, Neeley WL, Rompani S, Saigal S, Yang J, Klassen H, Langer R, Young MJ. Engineering retinal progenitor cell and scrollable poly(glycerol-sebacate) composites for expansion and subretinal transplantation. Biomaterials. 2009 Jul; 30(20):3405-14.
    View in: PubMed
  14. Saint-Geniez M, Maharaj AS, Walshe TE, Tucker BA, Sekiyama E, Kurihara T, Darland DC, Young MJ, D'Amore PA. Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors. PLoS One. 2008; 3(11):e3554.
    View in: PubMed
  15. Klassen H, Warfvinge K, Schwartz PH, Kiilgaard JF, Shamie N, Jiang C, Samuel M, Scherfig E, Prather RS, Young MJ. Isolation of progenitor cells from GFP-transgenic pigs and transplantation to the retina of allorecipients. Cloning Stem Cells. 2008 Sep; 10(3):391-402.
    View in: PubMed
  16. Tucker B, Klassen H, Yang L, Chen DF, Young MJ. Elevated MMP Expression in the MRL Mouse Retina Creates a Permissive Environment for Retinal Regeneration. Invest Ophthalmol Vis Sci. 2008 Apr; 49(4):1686-95.
    View in: PubMed
  17. Neeley WL, Redenti S, Klassen H, Tao S, Desai T, Young MJ, Langer R. A microfabricated scaffold for retinal progenitor cell grafting. Biomaterials. 2008 Feb; 29(4):418-26.
    View in: PubMed
  18. Klassen H, Schwartz PH, Ziaeian B, Nethercott H, Young MJ, Bragadottir R, Tullis GE, Warfvinge K, Narfstrom K. Neural precursors isolated from the developing cat brain show retinal integration following transplantation to the retina of the dystrophic cat. Vet Ophthalmol. 2007 Jul-Aug; 10(4):245-53.
    View in: PubMed
  19. Ng TF, Lavik E, Keino H, Taylor AW, Langer RS, Young MJ. Creating an immune-privileged site using retinal progenitor cells and biodegradable polymers. Stem Cells. 2007 Jun; 25(6):1552-9.
    View in: PubMed
  20. Zhang Y, Klassen HJ, Tucker BA, Perez MT, Young MJ. CNS progenitor cells promote a permissive environment for neurite outgrowth via a matrix metalloproteinase-2-dependent mechanism. J Neurosci. 2007 Apr 25; 27(17):4499-506.
    View in: PubMed
  21. Tao S, Young C, Redenti S, Zhang Y, Klassen H, Desai T, Young MJ. Survival, migration and differentiation of retinal progenitor cells transplanted on micro-machined poly(methyl methacrylate) scaffolds to the subretinal space. Lab Chip. 2007 Jun; 7(6):695-701.
    View in: PubMed
  22. Klassen H, Kiilgaard JF, Zahir T, Ziaeian B, Kirov I, Scherfig E, Warfvinge K, Young MJ. Progenitor cells from the porcine neural retina express photoreceptor markers after transplantation to the subretinal space of allorecipients. Stem Cells. 2007 May; 25(5):1222-30.
    View in: PubMed
  23. Ng TF, Klassen HJ, Hori J, Young MJ. Retinal transplantation. Chem Immunol Allergy. 2007; 92:300-16.
    View in: PubMed
  24. Zahir T, Klassen H, Tomita M, Young MJ. Sorbitol causes preferential selection of Muller glial precursors from late retinal progenitor cells in vitro. Mol Vis. 2006; 12:1606-14.
    View in: PubMed
  25. Tomita M, Mori T, Maruyama K, Zahir T, Ward M, Umezawa A, Young MJ. A comparison of neural differentiation and retinal transplantation with bone marrow-derived cells and retinal progenitor cells. Stem Cells. 2006 Oct; 24(10):2270-8.
    View in: PubMed
  26. Warfvinge K, Kiilgaard JF, Klassen H, Zamiri P, Scherfig E, Streilein W, Prause JU, Young MJ. Retinal progenitor cell xenografts to the pig retina: immunological reactions. Cell Transplant. 2006; 15(7):603-12.
    View in: PubMed
  27. Young MJ, Borrás T, Walter M, Ritch R. Tissue bioengineering: potential applications to glaucoma. Arch Ophthalmol. 2005 Dec; 123(12):1725-31.
    View in: PubMed
  28. Young MJ. Stem cells in the mammalian eye: a tool for retinal repair. APMIS. 2005 Nov-Dec; 113(11-12):845-57.
    View in: PubMed
  29. Tomita M, Lavik E, Klassen H, Zahir T, Langer R, Young MJ. Biodegradable polymer composite grafts promote the survival and differentiation of retinal progenitor cells. Stem Cells. 2005 Nov-Dec; 23(10):1579-88.
    View in: PubMed
  30. Warfvinge K, Kiilgaard JF, Lavik EB, Scherfig E, Langer R, Klassen HJ, Young MJ. Retinal progenitor cell xenografts to the pig retina: morphologic integration and cytochemical differentiation. Arch Ophthalmol. 2005 Oct; 123(10):1385-93.
    View in: PubMed
  31. Burdick JA, Ward M, Liang E, Young MJ, Langer R. Stimulation of neurite outgrowth by neurotrophins delivered from degradable hydrogels. Biomaterials. 2006 Jan; 27(3):452-9.
    View in: PubMed
  32. Zahir T, Klassen H, Young MJ. Effects of ciliary neurotrophic factor on differentiation of late retinal progenitor cells. Stem Cells. 2005 Mar; 23(3):424-32.
    View in: PubMed
  33. Klassen HJ, Ng TF, Kurimoto Y, Kirov I, Shatos M, Coffey P, Young MJ. Multipotent retinal progenitors express developmental markers, differentiate into retinal neurons, and preserve light-mediated behavior. Invest Ophthalmol Vis Sci. 2004 Nov; 45(11):4167-73.
    View in: PubMed
  34. Klassen H, Sakaguchi DS, Young MJ. Stem cells and retinal repair. Prog Retin Eye Res. 2004 Mar; 23(2):149-81.
    View in: PubMed
  35. Mizumoto H, Mizumoto K, Shatos MA, Klassen H, Young MJ. Retinal transplantation of neural progenitor cells derived from the brain of GFP transgenic mice. Vision Res. 2003 Jul; 43(16):1699-708.
    View in: PubMed
  36. Klassen HJ, Imfeld KL, Kirov II, Tai L, Gage FH, Young MJ, Berman MA. Expression of cytokines by multipotent neural progenitor cells. Cytokine. 2003 May; 22(3-4):101-6.
    View in: PubMed
  37. Klassen H, Imfeld KL, Ray J, Young MJ, Gage FH, Berman MA. The immunological properties of adult hippocampal progenitor cells. Vision Res. 2003 Apr; 43(8):947-56.
    View in: PubMed
  38. Van Hoffelen SJ, Young MJ, Shatos MA, Sakaguchi DS. Incorporation of murine brain progenitor cells into the developing mammalian retina. Invest Ophthalmol Vis Sci. 2003 Jan; 44(1):426-34.
    View in: PubMed
  39. Hori J, Ng TF, Shatos M, Klassen H, Streilein JW, Young MJ. Neural progenitor cells lack immunogenicity and resist destruction as allografts. Stem Cells. 2003; 21(4):405-16.
    View in: PubMed
  40. Ng TF, Osawa H, Hori J, Young MJ, Streilein JW. Allogeneic neonatal neuronal retina grafts display partial immune privilege in the subcapsular space of the kidney. J Immunol. 2002 Nov 15; 169(10):5601-6.
    View in: PubMed
  41. Young MJ, Lee RK, Jhaveri S, Wurtman RJ. Intracellular and cell-surface distribution of amyloid precursor protein in cortical astrocytes. Brain Res Bull. 1999 Sep 1; 50(1):27-32.
    View in: PubMed
  42. Young MJ, Lund RD. The retinal ganglion cells that drive the pupilloconstrictor response in rats. Brain Res. 1998 Mar 23; 787(2):191-202.
    View in: PubMed
  43. Young MJ, Lund RD. Parameters of transplant-mediated pupilloconstriction in rats with unilateral olivary pretectal lesions. J Comp Neurol. 1997 Nov 17; 388(2):327-35.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact Human Resources at faculty_serviceshms.harvard.edu.
Young's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
_
Co-Authors
_
Similar People
_
Same Department
Physical Neighbors
_