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Brian Lewis Edlow, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K23NS094538 (EDLOW, BRIAN L.) Sep 20, 2015 - Jun 30, 2020
    NIH/NINDS
    Brainstem Network Determinants of Recovery from Traumatic Coma
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Mazwi NL, Izzy S, Tan CO, Martinez S, Glenn MB, Giacino JT, Wu O, Zafonte R, Edlow BL. Traumatic Microbleeds in the Hippocampus and Corpus Callosum Predict Duration of Posttraumatic Amnesia. J Head Trauma Rehabil. 2019 May 16. PMID: 31033742.
    Citations:    
  2. Barra ME, Izzy S, Sarro-Schwartz A, Hirschberg RE, Mazwi N, Edlow BL. Stimulant Therapy in Acute Traumatic Brain Injury: Prescribing Patterns and Adverse Event Rates at 2 Level 1 Trauma Centers. J Intensive Care Med. 2019 Apr 09; 885066619841603. PMID: 30966863.
    Citations:    
  3. Stewart W, Allinson K, Al-Sarraj S, Bachmeier C, Barlow K, Belli A, Burns MP, Carson A, Crawford F, Dams-O'Connor K, Diaz-Arrastia R, Dixon CE, Edlow BL, Ferguson S, Fischl B, Folkerth RD, Gentleman S, Giza CC, Grady MS, Helmy A, Herceg M, Holton JL, Howell D, Hutchinson PJ, Iacono D, Iglesias JE, Ikonomovic MD, Johnson VE, Keene CD, Kofler JK, Koliatsos VE, Lee EB, Levin H, Lifshitz J, Ling H, Loane DJ, Love S, Maas AI, Marklund N, Master CL, McElvenny DM, Meaney DF, Menon DK, Montine TJ, Mouzon B, Mufson EJ, Ojo JO, Prins M, Revesz T, Ritchie CW, Smith C, Sylvester R, Tang CY, Trojanowski JQ, Urankar K, Vink R, Wellington C, Wilde EA, Wilson L, Yeates K, Smith DH. Primum non nocere: a call for balance when reporting on CTE. Lancet Neurol. 2019 Mar; 18(3):231-233. PMID: 30784550.
    Citations:    
  4. Bodien YG, Threlkeld ZD, Edlow BL. Default mode network dynamics in covert consciousness. Cortex. 2019 Jan 30. PMID: 30791975.
    Citations:    
  5. Pais-Roldán P, Edlow BL, Jiang Y, Stelzer J, Zou M, Yu X. Multimodal assessment of recovery from coma in a rat model of diffuse brainstem tegmentum injury. Neuroimage. 2019 04 01; 189:615-630. PMID: 30708105.
    Citations:    Fields:    
  6. Tian Q, Yang G, Leuze C, Rokem A, Edlow BL, McNab JA. Generalized diffusion spectrum magnetic resonance imaging (GDSI) for model-free reconstruction of the ensemble average propagator. Neuroimage. 2019 04 01; 189:497-515. PMID: 30684636.
    Citations:    Fields:    
  7. Edlow BL. Covert Consciousness: Searching for Volitional Brain Activity in the Unresponsive. Curr Biol. 2018 Dec 03; 28(23):R1345-R1348. PMID: 30513331.
    Citations:    Fields:    
  8. Edlow BL, Fins JJ. Assessment of Covert Consciousness in the Intensive Care Unit: Clinical and Ethical Considerations. J Head Trauma Rehabil. 2018 Nov/Dec; 33(6):424-434. PMID: 30395042.
    Citations:    Fields:    
  9. Lee S, Polimeni JR, Price CM, Edlow BL, McNab JA. Characterizing Signals Within Lesions and Mapping Brain Network Connectivity After Traumatic Axonal Injury: A 7 Tesla Resting-State FMRI Study. Brain Connect. 2018 06; 8(5):288-298. PMID: 29665699.
    Citations:    Fields:    
  10. Threlkeld ZD, Bodien YG, Rosenthal ES, Giacino JT, Nieto-Castanon A, Wu O, Whitfield-Gabrieli S, Edlow BL. Functional networks reemerge during recovery of consciousness after acute severe traumatic brain injury. Cortex. 2018 Sep; 106:299-308. PMID: 29871771.
    Citations:    Fields:    
  11. Chatelle C, Spencer CA, Cash SS, Hochberg LR, Edlow BL. Feasibility of an EEG-based brain-computer interface in the intensive care unit. Clin Neurophysiol. 2018 08; 129(8):1519-1525. PMID: 29804044.
    Citations:    Fields:    
  12. Edlow BL, Keene CD, Perl DP, Iacono D, Folkerth RD, Stewart W, Mac Donald CL, Augustinack J, Diaz-Arrastia R, Estrada C, Flannery E, Gordon WA, Grabowski TJ, Hansen K, Hoffman J, Kroenke C, Larson EB, Lee P, Mareyam A, McNab JA, McPhee J, Moreau AL, Renz A, Richmire K, Stevens A, Tang CY, Tirrell LS, Trittschuh EH, van der Kouwe A, Varjabedian A, Wald LL, Wu O, Yendiki A, Young L, Zöllei L, Fischl B, Crane PK, Dams-O'Connor K. Multimodal Characterization of the Late Effects of Traumatic Brain Injury: A Methodological Overview of the Late Effects of Traumatic Brain Injury Project. J Neurotrauma. 2018 07 15; 35(14):1604-1619. PMID: 29421973.
    Citations:    Fields:    
  13. Kenney K, Iacono D, Edlow BL, Katz DI, Diaz-Arrastia R, Dams-O'Connor K, Daneshvar DH, Stevens A, Moreau AL, Tirrell LS, Varjabedian A, Yendiki A, van der Kouwe A, Mareyam A, McNab JA, Gordon WA, Fischl B, McKee AC, Perl DP. Dementia After Moderate-Severe Traumatic Brain Injury: Coexistence of Multiple Proteinopathies. J Neuropathol Exp Neurol. 2018 Jan 01; 77(1):50-63. PMID: 29155947.
    Citations: 3     Fields:    Translation:HumansCells
  14. Bodien YG, Giacino JT, Edlow BL. Functional MRI Motor Imagery Tasks to Detect Command Following in Traumatic Disorders of Consciousness. Front Neurol. 2017; 8:688. PMID: 29326648.
    Citations: 4     
  15. Bodien YG, Chatelle C, Edlow BL. Functional Networks in Disorders of Consciousness. Semin Neurol. 2017 10; 37(5):485-502. PMID: 29207410.
    Citations: 1     Fields:    Translation:Humans
  16. Marehbian J, Muehlschlegel S, Edlow BL, Hinson HE, Hwang DY. Medical Management of the Severe Traumatic Brain Injury Patient. Neurocrit Care. 2017 Dec; 27(3):430-446. PMID: 28573388.
    Citations:    Fields:    Translation:Humans
  17. Izzy S, Mazwi NL, Martinez S, Spencer CA, Klein JP, Parikh G, Glenn MB, Greenberg SM, Greer DM, Wu O, Edlow BL. Revisiting Grade 3 Diffuse Axonal Injury: Not All Brainstem Microbleeds are Prognostically Equal. Neurocrit Care. 2017 Oct; 27(2):199-207. PMID: 28477152.
    Citations: 1     Fields:    Translation:Humans
  18. Edlow BL, Samuels O. Emergency Neurological Life Support: Subarachnoid Hemorrhage. Neurocrit Care. 2017 Sep; 27(Suppl 1):116-123. PMID: 28913624.
    Citations:    Fields:    Translation:Humans
  19. Edlow BL, Chatelle C, Spencer CA, Chu CJ, Bodien YG, O'Connor KL, Hirschberg RE, Hochberg LR, Giacino JT, Rosenthal ES, Wu O. Early detection of consciousness in patients with acute severe traumatic brain injury. Brain. 2017 Sep 01; 140(9):2399-2414. PMID: 29050383.
    Citations: 8     Fields:    Translation:Humans
  20. Raibagkar P, Chavali RV, Kaplan TB, Kim JA, Nitka MV, Chou SH, Edlow BL. Reverse Locked-In Syndrome. Neurocrit Care. 2017 Aug; 27(1):108-114. PMID: 28324264.
    Citations:    Fields:    Translation:Humans
  21. Edlow BL, Hurwitz S, Edlow JA. Diagnosis of DWI-negative acute ischemic stroke: A meta-analysis. Neurology. 2017 07 18; 89(3):256-262. PMID: 28615423.
    Citations: 2     Fields:    Translation:Humans
  22. Chung DY, Edlow BL. Teaching NeuroImages: Traumatic blown pupil without herniation. Neurology. 2017 05 09; 88(19):e190-e191. PMID: 28483996.
    Citations:    Fields:    Translation:Humans
  23. Bianciardi M, Strong C, Toschi N, Edlow BL, Fischl B, Brown EN, Rosen BR, Wald LL. A probabilistic template of human mesopontine tegmental nuclei from in vivo 7T MRI. Neuroimage. 2018 04 15; 170:222-230. PMID: 28476663.
    Citations:    Fields:    Translation:Humans
  24. Venkatraman A, Edlow BL, Immordino-Yang MH. The Brainstem in Emotion: A Review. Front Neuroanat. 2017; 11:15. PMID: 28337130.
    Citations: 9     
  25. Iacono D, Shively SB, Edlow BL, Perl DP. Chronic Traumatic Encephalopathy: Known Causes, Unknown Effects. Phys Med Rehabil Clin N Am. 2017 05; 28(2):301-321. PMID: 28390515.
    Citations:    Fields:    Translation:Humans
  26. Fischer DB, Boes AD, Demertzi A, Evrard HC, Laureys S, Edlow BL, Liu H, Saper CB, Pascual-Leone A, Fox MD, Geerling JC. A human brain network derived from coma-causing brainstem lesions. Neurology. 2016 Dec 06; 87(23):2427-2434. PMID: 27815400.
    Citations: 17     Fields:    Translation:Humans
  27. Nelson S, Edlow BL, Wu O, Rosenthal ES, Westover MB, Rordorf G. Default Mode Network Perfusion in Aneurysmal Subarachnoid Hemorrhage. Neurocrit Care. 2016 10; 25(2):237-42. PMID: 26800697.
    Citations: 1     Fields:    Translation:Humans
  28. Edlow AG, Edlow BL, Edlow JA. Diagnosis of Acute Neurologic Emergencies in Pregnant and Postpartum Women. Emerg Med Clin North Am. 2016 Nov; 34(4):943-965. PMID: 27741996.
    Citations:    Fields:    Translation:Humans
  29. Edlow BL, Copen WA, Izzy S, van der Kouwe A, Glenn MB, Greenberg SM, Greer DM, Wu O. Longitudinal Diffusion Tensor Imaging Detects Recovery of Fractional Anisotropy Within Traumatic Axonal Injury Lesions. Neurocrit Care. 2016 06; 24(3):342-52. PMID: 26690938.
    Citations: 3     Fields:    Translation:Humans
  30. Albin RL, Edlow BL, Rosenthal ES, Hinson HE. Blowing the whistle on sports concussions: Will the risk of dementia change the game? Neurology. 2016 05 17; 86(20):1929-30. PMID: 27185899.
    Citations: 1     Fields:    Translation:Humans
  31. Edlow BL, Lammers GJ. Bringing posttraumatic sleep-wake disorders out of the dark. Neurology. 2016 05 24; 86(21):1934-5. PMID: 27164689.
    Citations:    Fields:    Translation:Humans
  32. Tian Q, Rokem A, Folkerth RD, Nummenmaa A, Fan Q, Edlow BL, McNab JA. Q-space truncation and sampling in diffusion spectrum imaging. Magn Reson Med. 2016 12; 76(6):1750-1763. PMID: 26762670.
    Citations: 1     Fields:    Translation:Humans
  33. Edlow BL, Copen WA, Izzy S, Bakhadirov K, van der Kouwe A, Glenn MB, Greenberg SM, Greer DM, Wu O. Diffusion tensor imaging in acute-to-subacute traumatic brain injury: a longitudinal analysis. BMC Neurol. 2016 Jan 11; 16:2. PMID: 26754948.
    Citations: 8     Fields:    Translation:Humans
  34. Edlow BL, McNab JA, Witzel T, Kinney HC. The Structural Connectome of the Human Central Homeostatic Network. Brain Connect. 2016 Apr; 6(3):187-200. PMID: 26530629.
    Citations: 14     Fields:    Translation:Humans
  35. Bianciardi M, Toschi N, Edlow BL, Eichner C, Setsompop K, Polimeni JR, Brown EN, Kinney HC, Rosen BR, Wald LL. Toward an In Vivo Neuroimaging Template of Human Brainstem Nuclei of the Ascending Arousal, Autonomic, and Motor Systems. Brain Connect. 2015 Dec; 5(10):597-607. PMID: 26066023.
    Citations: 7     Fields:    Translation:Humans
  36. Edlow BL, Hinson HE. Blowing the whistle on sports concussions: Will the risk of dementia change the game? Neurology. 2015 Oct 27; 85(17):1442-3. PMID: 26253447.
    Citations:    Fields:    Translation:Humans
  37. Edlow BL, Rosenthal, ES. Diagnostic, Prognostic and Advanced Imaging in Severe Traumatic Brain Injury. Current Trauma Reports. 2015; (in press).
  38. Chu CJ, Tanaka N, Diaz J, Edlow BL, Wu O, Hämäläinen M, Stufflebeam S, Cash SS, Kramer MA. EEG functional connectivity is partially predicted by underlying white matter connectivity. Neuroimage. 2015 Mar; 108:23-33. PMID: 25534110.
    Citations: 10     Fields:    Translation:Humans
  39. Auriel E, Edlow BL, Reijmer YD, Fotiadis P, Ramirez-Martinez S, Ni J, Reed AK, Vashkevich A, Schwab K, Rosand J, Viswanathan A, Wu O, Gurol ME, Greenberg SM. Microinfarct disruption of white matter structure: a longitudinal diffusion tensor analysis. Neurology. 2014 Jul 08; 83(2):182-8. PMID: 24920857.
    Citations: 14     Fields:    Translation:Humans
  40. Kim MN, Edlow BL, Durduran T, Frangos S, Mesquita RC, Levine JM, Greenberg JH, Yodh AG, Detre JA. Continuous optical monitoring of cerebral hemodynamics during head-of-bed manipulation in brain-injured adults. Neurocrit Care. 2014 Jun; 20(3):443-53. PMID: 23653267.
    Citations: 14     Fields:    Translation:HumansCTClinical Trials
  41. Edlow BL, Kinney HC, Folkerth R. Authors' reply. J Neuropathol Exp Neurol. 2014 Mar; 73(3):268-9. PMID: 24525702.
    Citations:    Fields:    Translation:Humans
  42. Edlow BL, Giacino JT, Hirschberg RE, Gerrard J, Wu O, Hochberg LR. Unexpected recovery of function after severe traumatic brain injury: the limits of early neuroimaging-based outcome prediction. Neurocrit Care. 2013 Dec; 19(3):364-75. PMID: 23860665.
    Citations: 4     Fields:    Translation:Humans
  43. Edlow BL, Giacino JT, Wu O. Functional MRI and outcome in traumatic coma. Curr Neurol Neurosci Rep. 2013 Sep; 13(9):375. PMID: 23881623.
    Citations: 8     Fields:    Translation:HumansAnimals
  44. Edlow BL, Haynes RL, Takahashi E, Klein JP, Cummings P, Benner T, Greer DM, Greenberg SM, Wu O, Kinney HC, Folkerth RD. Disconnection of the ascending arousal system in traumatic coma. J Neuropathol Exp Neurol. 2013 Jun; 72(6):505-23. PMID: 23656993.
    Citations: 24     Fields:    Translation:Humans
  45. McNab JA, Edlow BL, Witzel T, Huang SY, Bhat H, Heberlein K, Feiweier T, Liu K, Keil B, Cohen-Adad J, Tisdall MD, Folkerth RD, Kinney HC, Wald LL. The Human Connectome Project and beyond: initial applications of 300 mT/m gradients. Neuroimage. 2013 Oct 15; 80:234-45. PMID: 23711537.
    Citations: 55     Fields:    Translation:HumansAnimals
  46. Westover MB, Edlow BL, Greer DM. Coma After Cardiac Arrest: Management and Neurological Prognostication. In: MGH Cardiology Board Review. Gaggin HK, Januzzi JL (Eds.), Springer, New York, NY. 2013.
  47. Edlow BL, Mehta B, Ramakrishnan P, Ropper AH. Neurological Critical Care. In: Pocket ICU, Frendl G, Urman RD (Eds.). Lippincott Williams and Wilkins, Philadelphia, PA. 2013.
  48. Edlow BL, Wu O. Advanced neuroimaging in traumatic brain injury. Semin Neurol. 2012 Sep; 32(4):374-400. PMID: 23361483.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  49. Edlow BL, Bove RM, Viswanathan A, Greenberg SM, Silverman SB. The pattern and pace of hyperacute hemorrhage expansion. Neurocrit Care. 2012 Oct; 17(2):250-4. PMID: 22826138.
    Citations: 5     Fields:    Translation:Humans
  50. Greer DM, Scripko PD, Wu O, Edlow BL, Bartscher J, Sims JR, Camargo EE, Singhal AB, Furie KL. Hippocampal magnetic resonance imaging abnormalities in cardiac arrest are associated with poor outcome. J Stroke Cerebrovasc Dis. 2013 Oct; 22(7):899-905. PMID: 22995378.
    Citations: 6     Fields:    Translation:Humans
  51. Edlow BL, Takahashi E, Wu O, Benner T, Dai G, Bu L, Grant PE, Greer DM, Greenberg SM, Kinney HC, Folkerth RD. Neuroanatomic connectivity of the human ascending arousal system critical to consciousness and its disorders. J Neuropathol Exp Neurol. 2012 Jun; 71(6):531-46. PMID: 22592840.
    Citations: 39     Fields:    Translation:Humans
  52. Walcott BP, Edlow BL, Xia Z, Kahle KT, Nahed BV, Schmahmann JD. Steroid responsive A3243G mutation MELAS: clinical and radiographic evidence for regional hyperperfusion leading to neuronal loss. Neurologist. 2012 May; 18(3):159-70. PMID: 22549360.
    Citations: 2     Fields:    Translation:Humans
  53. Vaidya A, Dolan BM, Edlow BL, Rinne ML, McGinnis SM. Interactive medical case. A startling decline. N Engl J Med. 2012 Feb 09; 366(6):e11. PMID: 22316470.
    Citations:    Fields:    Translation:Humans
  54. Chow FC, Edlow BL, Frosch MP, Copen WA, Greer DM. Outcome in patients with H1N1 influenza and cerebrovascular injury treated with extracorporeal membrane oxygenation. Neurocrit Care. 2011 Aug; 15(1):156-60. PMID: 21465323.
    Citations: 7     Fields:    Translation:HumansCells
  55. Edlow BL, Diamond EL. Teaching NeuroImages: restricted diffusion in the corpus callosum after traumatic diffuse axonal injury. Neurology. 2010 Oct 26; 75(17):e69. PMID: 20975045.
    Citations: 1     Fields:    Translation:Humans
  56. Edlow BL, Ramakrishnan P, Mehta B, Ropper AH. Neurocritical Care. In: Pocket Neurology. Westover MB, Choi E, Awad K, Greer DM (Eds.), Lippincott Williams and Wilkins, Philadelphia, PA. 2010.
  57. Edlow BL, Wainger BJ, Frosch MP, Copen WA, Rathmell JP, Rost NS. Posterior circulation stroke after C1-C2 intraarticular facet steroid injection: evidence for diffuse microvascular injury. Anesthesiology. 2010 Jun; 112(6):1532-5. PMID: 20460995.
    Citations: 3     Fields:    Translation:Humans
  58. Leesch W, Edlow BL, Yoo AJ, Greer DM. Subarachnoid contrast extravasation after intravenous and intra-arterial reperfusion therapy. Neurology. 2010 Apr 20; 74(16):1328. PMID: 20404314.
    Citations: 1     Fields:    Translation:Humans
  59. Kim MN, Durduran T, Frangos S, Edlow BL, Buckley EM, Moss HE, Zhou C, Yu G, Choe R, Maloney-Wilensky E, Wolf RL, Grady MS, Greenberg JH, Levine JM, Yodh AG, Detre JA, Kofke WA. Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults. Neurocrit Care. 2010 Apr; 12(2):173-80. PMID: 19908166.
    Citations: 75     Fields:    Translation:Humans
  60. Edlow BL, Kim MN, Durduran T, Zhou C, Putt ME, Yodh AG, Greenberg JH, Detre JA. The effects of healthy aging on cerebral hemodynamic responses to posture change. Physiol Meas. 2010 Apr; 31(4):477-95. PMID: 20181999.
    Citations: 13     Fields:    Translation:Humans
  61. Durduran T, Zhou C, Edlow BL, Yu G, Choe R, Kim MN, Cucchiara BL, Putt ME, Shah Q, Kasner SE, Greenberg JH, Yodh AG, Detre JA. Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients. Opt Express. 2009 Mar 02; 17(5):3884-902. PMID: 19259230.
    Citations: 37     Fields:    Translation:Humans
  62. Wu WC, Edlow BL, Elliot MA, Wang J, Detre JA. Physiological modulations in arterial spin labeling perfusion magnetic resonance imaging. IEEE Trans Med Imaging. 2009 May; 28(5):703-9. PMID: 19150788.
    Citations: 23     Fields:    Translation:Humans
  63. Fernández-Seara MA, Edlow BL, Hoang A, Wang J, Feinberg DA, Detre JA. Minimizing acquisition time of arterial spin labeling at 3T. Magn Reson Med. 2008 Jun; 59(6):1467-71. PMID: 18506806.
    Citations: 37     Fields:    Translation:Humans
  64. Belkora J, Edlow B, Aviv C, Sepucha K, Esserman L. Training community resource center and clinic personnel to prompt patients in listing questions for doctors: follow-up interviews about barriers and facilitators to the implementation of consultation planning. Implement Sci. 2008 Jan 31; 3:6. PMID: 18237380.
    Citations: 6     Fields:    
  65. Edlow BL, Hamilton K, Hamilton RH. Teaching about the brain and reaching the community: undergraduates in the pipeline neuroscience program at the university of pennsylvania. J Undergrad Neurosci Educ. 2007; 5(2):A63-70. PMID: 23493190.
    Citations: 1     
  66. Edlow BL, Kasner SE, Hurst RW, Weigele JB, Levine JM. Reversible cerebral vasoconstriction syndrome associated with subarachnoid hemorrhage. Neurocrit Care. 2007; 7(3):203-10. PMID: 17901935.
    Citations: 9     Fields:    Translation:Humans
  67. Edlow BL, Burnett MG, Belasco J, Marcotte PJ, D'Angio G, Furth EE. Recurring polysomatic hemangiomatosis: a new syndrome? J Pediatr Hematol Oncol. 2006 Jul; 28(7):471-5. PMID: 16825996.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.