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Last Name

profileDae Hyun Kim, Sc.D., M.D.

TitleAssistant Professor of Medicine
InstitutionBrigham and Women's Hospital
AddressBrigham and Women's Hospital
Pharmaco Epi Division
1620 Tremont St
Boston MA 02120
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Collapse education and training
Yonsei University, Seoul, KoreaMD02/2001Medicine
Johns Hopkins Bloomberg School of Public Health, Baltimore, MDMPH05/2005Epidemiology
Thomas Jefferson University Hospital, Philadelphia, PA06/2008Internal Medicine
Beth Israel Deaconess Medical Center, Boston, MA06/2010Geriatric Medicine
Harvard T. H. Chan School of Public Health, Boston, MAScD05/2014Epidemiology

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
P30AG048785     (LACHMAN, MARGIE E)Jun 1, 2017 - May 31, 2018
Home-based Exercise Program for Recovery after Transcatheter Aortic Valve Replacement: A Pilot Randomized Controlled Trial
Role: Pilot Study PI

P30AG031679     (BHASIN, SHALENDAR)Jul 1, 2016 - Jun 30, 2018
Home-based Exercise Program for Recovery after Transcatheter Aortic Valve Replacement: A Pilot Randomized Controlled Trial
Role: Pilot Study PI

K08AG051187     (KIM, DAE HYUN)Aug 1, 2015 - Apr 30, 2018
Development and Validation of a Frailty Index Using Claims Data for Pharmacoepidemiologic Studies in Older Adults
Role: Principal Investigator

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Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Drudi LM, Ades M, Turkdogan S, Huynh C, Lauck S, Webb JG, Piazza N, Martucci G, Langlois Y, Perrault LP, Asgar AW, Labinaz M, Lamy A, Noiseux N, Peterson MD, Arora RC, Lindman BR, Bendayan M, Mancini R, Trnkus A, Kim DH, Popma JJ, Afilalo J. Association of Depression With Mortality in Older Adults Undergoing Transcatheter or Surgical Aortic Valve Replacement. JAMA Cardiol. 2018 Jan 17. PMID: 29344620.
    View in: PubMed
  2. Kim DH. Perioperative Care of the Elderly Patient. Frailty and Functional Assessment. 2018.
  3. Kim DH, Schneeweiss S, Glynn RJ, Lipsitz LA, Rockwood K, Avorn J. Measuring Frailty in Medicare Data: Development and Validation of a Claims-Based Frailty Index. J Gerontol A Biol Sci Med Sci. 2017 Dec 13. PMID: 29244057.
    View in: PubMed
  4. Pak K, Uno H, Kim DH, Tian L, Kane RC, Takeuchi M, Fu H, Claggett B, Wei LJ. Interpretability of Cancer Clinical Trial Results Using Restricted Mean Survival Time as an Alternative to the Hazard Ratio. JAMA Oncol. 2017 12 01; 3(12):1692-1696. PMID: 28975263.
    View in: PubMed
  5. Kim DH, Uno H, Wei LJ. Restricted Mean Survival Time as a Measure to Interpret Clinical Trial Results. JAMA Cardiol. 2017 Nov 01; 2(11):1179-1180. PMID: 28877311.
    View in: PubMed
  6. Forman DE, Kim DH. Limitations of Treating Heart Rate as the Primary Outcome Determinant in Older Adults. J Am Coll Cardiol. 2017 Oct 10; 70(15):1872-1874. PMID: 28982500.
    View in: PubMed
  7. Jang IY, Jung HW, Lee CK, Lee YS, Lee E, Kim DH. Comparison Between Korean Version of Physical Activity Scale for the Elderly and International Physical Activity Questionnaire-Short Form in Evaluation of Frailty Phenotype. Ann Geriatr Med Res. 2017; (21):101-107.
  8. Afilalo J, Lauck S, Kim DH, Lefèvre T, Piazza N, Lachapelle K, Martucci G, Lamy A, Labinaz M, Peterson MD, Arora RC, Noiseux N, Rassi A, Palacios IF, Généreux P, Lindman BR, Asgar AW, Kim CA, Trnkus A, Morais JA, Langlois Y, Rudski LG, Morin JF, Popma JJ, Webb JG, Perrault LP. Frailty in Older Adults Undergoing Aortic Valve Replacement: The FRAILTY-AVR Study. J Am Coll Cardiol. 2017 Aug 08; 70(6):689-700. PMID: 28693934.
    View in: PubMed
  9. Kim DH, Lee J, Kim CA, Huybrechts KF, Bateman BT, Patorno E, Marcantonio ER. Evaluation of algorithms to identify delirium in administrative claims and drug utilization database. Pharmacoepidemiol Drug Saf. 2017 Aug; 26(8):945-953. PMID: 28485014.
    View in: PubMed
  10. Stolker J, Kim DH, Rich MR. Hurst's the Heart. Cardiovascular Disease in the Elderly: Pathophysiology and Clinical Implications. 2017.
  11. Jang IY, Jung HW, Lee CK, Jang KH, Cho EI, Jung JJ, Park E, Kim J, Lee YS, Lee E, Kim DH. Korean version of the Fatigue, Resistance, Ambulation, Illnesses and Loss of weight questionnaire versus the Modified Kihon Checklist for Frailty Screening in Community-Dwelling Older Adults: The Aging Study of PyeongChang Rural Area. Geriatr Gerontol Int. 2017 Nov; 17(11):2046-2052. PMID: 28371215.
    View in: PubMed
  12. Kim DH, Huybrechts KF, Patorno E, Marcantonio ER, Park Y, Levin R, Abdurrob A, Bateman BT. Adverse Events Associated with Antipsychotic Use in Hospitalized Older Adults After Cardiac Surgery. J Am Geriatr Soc. 2017 Jun; 65(6):1229-1237. PMID: 28186624.
    View in: PubMed
  13. Kim DH. Intensive vs Standard Blood Pressure Control for Older Adults. JAMA. 2016 Nov 08; 316(18):1921. PMID: 27825001.
    View in: PubMed
  14. Kim DH, Kim CA, Placide S, Lipsitz LA, Marcantonio ER. Preoperative Frailty Assessment and Outcomes at 6 Months or Later in Older Adults Undergoing Cardiac Surgical Procedures: A Systematic Review. Ann Intern Med. 2016 Nov 01; 165(9):650-660. PMID: 27548070.
    View in: PubMed
  15. Kim DH, Pieper CF, Ahmed A, Colón-Emeric CS. Use and Interpretation of Propensity Scores in Aging Research: A Guide for Clinical Researchers. J Am Geriatr Soc. 2016 Oct; 64(10):2065-2073. PMID: 27550392.
    View in: PubMed
  16. Sanders JL, Arnold AM, Hirsch CH, Thielke SM, Kim D, Mukamal KJ, Kizer JR, Ix JH, Kaplan RC, Kritchevsky SB, Newman AB. Effects of Disease Burden and Functional Adaptation on Morbidity and Mortality on Older Adults. J Am Geriatr Soc. 2016 Jun; 64(6):1242-9. PMID: 27321602; PMCID: PMC4922749 [Available on 06/01/17].
  17. Kim DH, Rich MW. Patient-Centred Care of Older Adults With Cardiovascular Disease and Multiple Chronic Conditions. Can J Cardiol. 2016 Sep; 32(9):1097-107. PMID: 27378591; PMCID: PMC5003648 [Available on 09/01/17].
  18. Jang IY, Jung HW, Lee CK, Lee YS, Kim KI, Kim KW, Oh H, Ji MY, Lee E, Kim DH. Rural and Urban Disparities in Frailty and Aging-Related Health Conditions in Korea. J Am Geriatr Soc. 2016 Apr; 64(4):908-11. PMID: 27100601.
    View in: PubMed
  19. Kim SC, Kim DH, Mogun H, Eddings W, Polinski JM, Franklin JM, Solomon DH. Impact of the U.S. Food and Drug Administration's Safety-Related Announcements on the Use of Bisphosphonates After Hip Fracture. J Bone Miner Res. 2016 Aug; 31(8):1536-40. PMID: 26969902; PMCID: PMC5040596 [Available on 08/01/17].
  20. Jung HW, Jang IY, Lee YS, Lee CK, Cho EI, Kang WY, Chae JH, Lee EJ, Kim DH. Prevalence of Frailty and Aging-Related Health Conditions in Older Koreans in Rural Communities: a Cross-Sectional Analysis of the Aging Study of Pyeongchang Rural Area. J Korean Med Sci. 2016 Mar; 31(3):345-52. PMID: 26952571; PMCID: PMC4779857.
  21. Kim DH, Grodstein F, Newman AB, Chaves PH, Odden MC, Klein R, Sarnak MJ, Lipsitz LA. Microvascular and Macrovascular Abnormalities and Cognitive and Physical Function in Older Adults: Cardiovascular Health Study. J Am Geriatr Soc. 2015 Sep; 63(9):1886-93. PMID: 26338279; PMCID: PMC4578971.
  22. Kim CA, Kim DH. Statins Provide Less Benefit in Populations with High Noncardiovascular Mortality Risk: Meta-Regression of Randomized Controlled Trials. J Am Geriatr Soc. 2015 Jul; 63(7):1413-9. PMID: 26173475; PMCID: PMC4509928.
  23. Kim DH, Rogers JR, Fulchino LA, Kim CA, Solomon DH, Kim SC. Bisphosphonates and risk of cardiovascular events: a meta-analysis. PLoS One. 2015; 10(4):e0122646. PMID: 25884398; PMCID: PMC4401508.
  24. Fowler-Brown A, Kim DH, Shi L, Marcantonio E, Wee CC, Shmerling RH, Leveille S. The mediating effect of leptin on the relationship between body weight and knee osteoarthritis in older adults. Arthritis Rheumatol. 2015 Jan; 67(1):169-75. PMID: 25302634.
    View in: PubMed
  25. Kiely DK, Kim DH, Gross AL, Habtemariam DA, Leveille SG, Li W, Lipsitz LA. Fall Risk is Not Black and White. J Health Dispar Res Pract. 2015; 8(3):72-84. PMID: 26855845.
    View in: PubMed
  26. Kim DH, Schneeweiss S. Measuring frailty using claims data for pharmacoepidemiologic studies of mortality in older adults: evidence and recommendations. Pharmacoepidemiol Drug Saf. 2014 Sep; 23(9):891-901. PMID: 24962929; PMCID: PMC4149846.
  27. Kim DH, Grodstein F, Newman AB, Chaves PH, Odden MC, Klein R, Sarnak MJ, Patel KV, Lipsitz LA. Prognostic implications of microvascular and macrovascular abnormalities in older adults: cardiovascular health study. J Gerontol A Biol Sci Med Sci. 2014 Dec; 69(12):1495-502. PMID: 24864308; PMCID: PMC4271022.
  28. Kim CA, Rasania SP, Afilalo J, Popma JJ, Lipsitz LA, Kim DH. Functional status and quality of life after transcatheter aortic valve replacement: a systematic review. Ann Intern Med. 2014 Feb 18; 160(4):243-54. PMID: 24727842; PMCID: PMC4039034.
  29. Kim DH, Newman AB, Lipsitz LA. Prediction of severe, persistent activity-of-daily-living disability in older adults. Am J Epidemiol. 2013 Oct 01; 178(7):1085-93. PMID: 23785110; PMCID: PMC3783096.
  30. Kim DH, Kim C, Ding EL, Townsend MK, Lipsitz LA. Adiponectin levels and the risk of hypertension: a systematic review and meta-analysis. Hypertension. 2013 Jul; 62(1):27-32. PMID: 23716587; PMCID: PMC3729220.
  31. Kim DH, Grodstein F, Rosner B, Kang JH, Cook NR, Manson JE, Buring JE, Willett WC, Okereke OI. Seafood types and age-related cognitive decline in the Women's Health Study. J Gerontol A Biol Sci Med Sci. 2013 Oct; 68(10):1255-62. PMID: 23554464; PMCID: PMC3779629.
  32. Thielke SM, Whitson H, Diehr P, O'Hare A, Kearney PM, Chaudhry SI, Zakai NA, Kim D, Sekaran N, Sale JE, Arnold AM, Chaves P, Newman A. Persistence and remission of musculoskeletal pain in community-dwelling older adults: results from the cardiovascular health study. J Am Geriatr Soc. 2012 Aug; 60(8):1393-400. PMID: 22861385; PMCID: PMC3633775.
  33. Kiely DK, Gross AL, Kim DH, Lipsitz LA. The association of educational attainment and SBP among older community-living adults: the Maintenance of Balance, Independent Living, Intellect and Zest in the Elderly (MOBILIZE) Boston Study. J Hypertens. 2012 Aug; 30(8):1518-25. PMID: 22688267; PMCID: PMC3447007.
  34. Okereke OI, Rosner BA, Kim DH, Kang JH, Cook NR, Manson JE, Buring JE, Willett WC, Grodstein F. Dietary fat types and 4-year cognitive change in community-dwelling older women. Ann Neurol. 2012 Jul; 72(1):124-34. PMID: 22605573; PMCID: PMC3405188.
  35. Kim DH. Differences in blood pressure between arms. BMJ. 2012 Mar 20; 344:e2033. PMID: 22433976.
    View in: PubMed
  36. Kim DH, Chaves PH, Newman AB, Klein R, Sarnak MJ, Newton E, Strotmeyer ES, Burke GL, Lipsitz LA. Retinal microvascular signs and disability in the Cardiovascular Health Study. Arch Ophthalmol. 2012 Mar; 130(3):350-6. PMID: 22084159; PMCID: PMC3520093.
  37. Kim DH, Brown RT, Ding EL, Kiel DP, Berry SD. Dementia medications and risk of falls, syncope, and related adverse events: meta-analysis of randomized controlled trials. J Am Geriatr Soc. 2011 Jun; 59(6):1019-31. PMID: 21649634; PMCID: PMC3260523.
  38. Kim DH. A potential selection bias in the study of early combination antibiotic therapy versus monotherapy in septic shock. Crit Care Med. 2011 Jun; 39(6):1604; author reply 1604-5. PMID: 21610652.
    View in: PubMed
  39. Kim DH, Newman AB, Hajjar I, Strotmeyer ES, Klein R, Newton E, Sarnak MJ, Burke GL, Lipsitz LA. Retinal microvascular signs and functional loss in older persons: the cardiovascular health study. Stroke. 2011 Jun; 42(6):1589-95. PMID: 21493913; PMCID: PMC3127407.
  40. Kim DH, Choi SE. Frailty index for patients with coronary artery disease. J Am Geriatr Soc. 2011 Feb; 59(2):373-4; author reply 374-5. PMID: 21314660.
    View in: PubMed
  41. Kim DH. Treating vascular risk factors in Alzheimer's disease. J Am Geriatr Soc. 2010 Jan; 58(1):185-6; author reply 186-7. PMID: 20122056.
    View in: PubMed
  42. Kim DH. Challenges in Antihypertensive Therapy in Older Persons. Annals of Long-Term Care: Clinical Care and Aging. 2010; 18:27-32.
  43. Hajjar I, Kim DH. Management of Hypertension in Older Adults. Case-Based Geriatrics. 2010.
  44. Kim DH, Daskalakis C, Silvestry SC, Sheth MP, Lee AN, Adams S, Hohmann S, Medvedev S, Whellan DJ. Aspirin and clopidogrel use in the early postoperative period following on-pump and off-pump coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2009 Dec; 138(6):1377-84. PMID: 19931667.
    View in: PubMed
  45. Kim DH. Low diastolic blood pressure and mortality in elderly people. J Am Geriatr Soc. 2009 Nov; 57(11):2176-7. PMID: 20121980.
    View in: PubMed
  46. Kim DH, Sagar UN, Adams S, Whellan DJ. Lifestyle risk factors and utilization of preventive services in disabled elderly adults in the community. J Community Health. 2009 Oct; 34(5):440-8. PMID: 19517224.
    View in: PubMed
  47. Park SE, Kang ES, Kim DH, Kim SK, Lee JH, Ahn CW, Lee HC, Cha BS. Effect of ABCA1 variant on atherogenic dyslipidaemia in patients with Type 2 diabetes treated with rosiglitazone. Diabet Med. 2009 Jun; 26(6):577-81. PMID: 19538231.
    View in: PubMed
  48. Kim DH, Hajjar I. Blood pressure and mortality in very old people. J Am Geriatr Soc. 2009 May; 57(5):940-1. PMID: 19470028; PMCID: PMC2803047.
  49. Kim DH, Daskalakis C, Whellan DJ, Whitman IR, Hohmann S, Medvedev S, Kraft WK. Safety of selective serotonin reuptake inhibitor in adults undergoing coronary artery bypass grafting. Am J Cardiol. 2009 May 15; 103(10):1391-5. PMID: 19427434.
    View in: PubMed
  50. Kim DH, Chung HJ, Bleys J, Ghohestani RF. Is paromomycin an effective and safe treatment against cutaneous leishmaniasis? A meta-analysis of 14 randomized controlled trials. PLoS Negl Trop Dis. 2009; 3(2):e381. PMID: 19221595; PMCID: PMC2637543.
  51. Park SE, Kim HM, Kim DH, Kim J, Cha BS, Kim DJ. The association between sleep duration and general and abdominal obesity in Koreans: data from the Korean National Health and Nutrition Examination Survey, 2001 and 2005. Obesity (Silver Spring). 2009 Apr; 17(4):767-71. PMID: 19180067.
    View in: PubMed
  52. Chung HJ, Kim DH, Lee KY, Chung KY. Painful red plaques at injection sites. Am J Clin Dermatol. 2009; 10(3):201-3. PMID: 19354336.
    View in: PubMed
  53. Kim DH, Daskalakis C, Lee AN, Adams S, Hohmann S, Silvestry SC, Medvedev S, Whellan DJ. Racial disparity in the relationship between hospital volume and mortality among patients undergoing coronary artery bypass grafting. Ann Surg. 2008 Nov; 248(5):886-92. PMID: 18948819.
    View in: PubMed
  54. Kim DH, Daskalakis C, Plumb JD, Adams S, Brawer R, Orr N, Hawthorne K, Toto EC, Whellan DJ. Modifiable cardiovascular risk factors among individuals in low socioeconomic communities and homeless shelters. Fam Community Health. 2008 Oct-Dec; 31(4):269-80. PMID: 18794634.
    View in: PubMed
  55. Kim DH, Sabour S, Sagar UN, Adams S, Whellan DJ. Prevalence of hypovitaminosis D in cardiovascular diseases (from the National Health and Nutrition Examination Survey 2001 to 2004). Am J Cardiol. 2008 Dec 01; 102(11):1540-4. PMID: 19026311.
    View in: PubMed
  56. Park SE, Kim DH, Lee JH, Park JS, Kang ES, Ahn CW, Lee HC, Cha BS. Retinol-binding protein-4 is associated with endothelial dysfunction in adults with newly diagnosed type 2 diabetes mellitus. Atherosclerosis. 2009 May; 204(1):23-5. PMID: 18838136.
    View in: PubMed
  57. Kim DH, Lipsitz LA, Ferrucci L, Varadhan R, Guralnik JM, Carlson MC, Fleisher LA, Fried LP, Chaves PH. Association between reduced heart rate variability and cognitive impairment in older disabled women in the community: Women's Health and Aging Study I. J Am Geriatr Soc. 2006 Nov; 54(11):1751-7. PMID: 17087704; PMCID: PMC2276586.
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