Harvard Catalyst Profiles

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Junichi Tokuda, PH.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01EB020667 (TOKUDA, JUNICHI) Jul 1, 2015 - Jun 30, 2018
    OpenIGTLink: a network communication interface for closed-loop image-guided interventions
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Moreira P, Patel N, Wartenberg M, Li G, Tuncali K, Heffter T, Burdette EC, Iordachita I, Fischer GS, Hata N, Tempany CM, Tokuda J. Evaluation of robot-assisted MRI-guided prostate biopsy: needle path analysis during clinical trials. Phys Med Biol. 2018 Oct 16; 63(20):20NT02. PMID: 30226214.
    View in: PubMed
  2. Wartenberg M, Schornak J, Gandomi K, Carvalho P, Nycz C, Patel N, Iordachita I, Tempany C, Hata N, Tokuda J, Fischer GS. Closed-Loop Active Compensation for Needle Deflection and Target Shift During Cooperatively Controlled Robotic Needle Insertion. Ann Biomed Eng. 2018 Oct; 46(10):1582-1594. PMID: 29926303.
    View in: PubMed
  3. Tokuda J, Chauvin L, Ninni B, Kato T, King F, Tuncali K, Hata N. Motion compensation for MRI-compatible patient-mounted needle guide device: estimation of targeting accuracy in MRI-guided kidney cryoablations. Phys Med Biol. 2018 Apr 13; 63(8):085010. PMID: 29546845.
    View in: PubMed
  4. Hovet S, Ren H, Xu S, Wood B, Tokuda J, Tse ZTH. MRI-powered biomedical devices. Minim Invasive Ther Allied Technol. 2018 Aug; 27(4):191-202. PMID: 29141515.
    View in: PubMed
  5. Doba N, Fukuda H, Numata K, Hao Y, Hara K, Nozaki A, Kondo M, Chuma M, Tanaka K, Takebayashi S, Koizumi N, Kobayashi A, Tokuda J, Maeda S. A new device for fiducial registration of image-guided navigation system for liver RFA. Int J Comput Assist Radiol Surg. 2018 Jan; 13(1):115-124. PMID: 28718001.
    View in: PubMed
  6. de Arcos J, Schmidt EJ, Wang W, Tokuda J, Vij K, Seethamraju RT, Damato AL, Dumoulin CL, Cormack RA, Viswanathan AN. Prospective Clinical Implementation of a Novel Magnetic Resonance Tracking Device for Real-Time Brachytherapy Catheter Positioning. Int J Radiat Oncol Biol Phys. 2017 11 01; 99(3):618-626. PMID: 28843373.
    View in: PubMed
  7. Frank T, Krieger A, Leonard S, Patel NA, Tokuda J. ROS-IGTL-Bridge: an open network interface for image-guided therapy using the ROS environment. Int J Comput Assist Radiol Surg. 2017 Aug; 12(8):1451-1460. PMID: 28567563.
    View in: PubMed
  8. Johnson M, Chen Y, Hovet S, Xu S, Wood B, Ren H, Tokuda J, Tse ZTH. Fabricating biomedical origami: a state-of-the-art review. Int J Comput Assist Radiol Surg. 2017 Nov; 12(11):2023-2032. PMID: 28260164.
    View in: PubMed
  9. Su H, Iordachita II, Tokuda J, Hata N, Liu X, Seifabadi R, Xu S, Wood B, Fischer GS. Fiber Optic Force Sensors for MRI-Guided Interventions and Rehabilitation: A Review. IEEE Sens J. 2017 Apr 01; 17(7):1952-1963. PMID: 28652857.
    View in: PubMed
  10. Kapur T, Pieper S, Fedorov A, Fillion-Robin JC, Halle M, O'Donnell L, Lasso A, Ungi T, Pinter C, Finet J, Pujol S, Jagadeesan J, Tokuda J, Norton I, Estepar RSJ, Gering D, Aerts HJWL, Jakab M, Hata N, Ibanez L, Blezek D, Miller J, Aylward S, Grimson WEL, Fichtinger G, Wells WM, Lorensen WE, Schroeder W, Kikinis R. Increasing the impact of medical image computing using community-based open-access hackathons: The NA-MIC and 3D Slicer experience. Med Image Anal. 2016 10; 33:176-180. PMID: 27498015.
    View in: PubMed
  11. Ciris PA, Balasubramanian M, Seethamraju RT, Tokuda J, Scalera J, Penzkofer T, Fennessy FM, Tempany-Afdhal CM, Tuncali K, Mulkern RV. Characterization of gradient echo signal decays in healthy and cancerous prostate at 3T improves with a Gaussian augmentation of the mono-exponential (GAME) model. NMR Biomed. 2016 07; 29(7):999-1009. PMID: 27241215; PMCID: PMC4957529.
  12. Tani S, Tatli S, Hata N, Garcia-Rojas X, Olubiyi OI, Silverman SG, Tokuda J. Three-dimensional quantitative assessment of ablation margins based on registration of pre- and post-procedural MRI and distance map. Int J Comput Assist Radiol Surg. 2016 Jun; 11(6):1133-42. PMID: 27038962; PMCID: PMC4893989.
  13. Hata N, Song SE, Olubiyi O, Arimitsu Y, Fujimoto K, Kato T, Tuncali K, Tani S, Tokuda J. Body-mounted robotic instrument guide for image-guided cryotherapy of renal cancer. Med Phys. 2016 Feb; 43(2):843-53. PMID: 26843245; PMCID: PMC4723400 [Available on 02/01/17].
  14. Wang W, Viswanathan AN, Damato AL, Chen Y, Tse Z, Pan L, Tokuda J, Seethamraju RT, Dumoulin CL, Schmidt EJ, Cormack RA. Evaluation of an active magnetic resonance tracking system for interstitial brachytherapy. Med Phys. 2015 Dec; 42(12):7114-21. PMID: 26632065; PMCID: PMC4662673.
  15. Su H, Shang W, Cole G, Li G, Harrington K, Camilo A, Tokuda J, Tempany CM, Hata N, Fischer GS. Piezoelectrically Actuated Robotic System for MRI-Guided Prostate Percutaneous Therapy. IEEE ASME Trans Mechatron. 2015 Aug; 20(4):1920-1932. PMID: 26412962.
    View in: PubMed
  16. Eslami S, Shang W, Li G, Patel N, Fischer GS, Tokuda J, Hata N, Tempany CM, Iordachita I. In-bore prostate transperineal interventions with an MRI-guided parallel manipulator: system development and preliminary evaluation. Int J Med Robot. 2016 Jun; 12(2):199-213. PMID: 26111458; PMCID: PMC4691445 [Available on 06/01/17].
  17. Tokuda J, Plishker W, Torabi M, Olubiyi OI, Zaki G, Tatli S, Silverman SG, Shekher R, Hata N. Graphics Processing Unit-Accelerated Nonrigid Registration of MR Images to CT Images During CT-Guided Percutaneous Liver Tumor Ablations. Acad Radiol. 2015 Jun; 22(6):722-33. PMID: 25784325; PMCID: PMC4428967.
  18. Tilak G, Tuncali K, Song SE, Tokuda J, Olubiyi O, Fennessy F, Fedorov A, Penzkofer T, Tempany C, Hata N. 3T MR-guided in-bore transperineal prostate biopsy: A comparison of robotic and manual needle-guidance templates. J Magn Reson Imaging. 2015 Jul; 42(1):63-71. PMID: 25263213; PMCID: PMC4376663.
  19. Penzkofer T, Tuncali K, Fedorov A, Song SE, Tokuda J, Fennessy FM, Vangel MG, Kibel AS, Mulkern RV, Wells WM, Hata N, Tempany CM. Transperineal in-bore 3-T MR imaging-guided prostate biopsy: a prospective clinical observational study. Radiology. 2015 Jan; 274(1):170-80. PMID: 25222067; PMCID: PMC4334270.
  20. Tauscher S, Tokuda J, Schreiber G, Neff T, Hata N, Ortmaier T. OpenIGTLink interface for state control and visualisation of a robot for image-guided therapy systems. Int J Comput Assist Radiol Surg. 2015 Mar; 10(3):285-92. PMID: 24923473; PMCID: PMC4265315.
  21. Wang W, Dumoulin CL, Viswanathan AN, Tse ZT, Mehrtash A, Loew W, Norton I, Tokuda J, Seethamraju RT, Kapur T, Damato AL, Cormack RA, Schmidt EJ. Real-time active MR-tracking of metallic stylets in MR-guided radiation therapy. Magn Reson Med. 2015 May; 73(5):1803-11. PMID: 24903165; PMCID: PMC4257908.
  22. Eslami S, Fischer GS, Song SE, Tokuda J, Hata N, Tempany CM, Iordachita I. Towards Clinically Optimized MRI-guided Surgical Manipulator for Minimally Invasive Prostate Percutaneous Interventions: Constructive Design. IEEE Int Conf Robot Autom. 2013 Dec 31; 20132:1228-1233. PMID: 24683502.
    View in: PubMed
  23. Lewis J, Mamata H, Tokuda J, Mishra P, Hermann G, Hatabu H, Nishino M, Mak R. TH-C-141-08: A Feasibility Study of the Utility of Dynamic Contrast-Enhanced MRI for Treatment Planning and Monitoring Treatment Response in Lung Stereotactic Body Radiation Therapy. Med Phys. 2013 Jun; 40(6Part33):540. PMID: 28519198.
    View in: PubMed
  24. Li G, Su H, Shang W, Tokuda J, Hata N, Tempany CM, Fischer GS. A Fully Actuated Robotic Assistant for MRI-Guided Prostate Biopsy and Brachytherapy. Proc SPIE Int Soc Opt Eng. 2013 Mar 12; 8671:867117. PMID: 25076821.
    View in: PubMed
  25. Song SE, Tokuda J, Tuncali K, Tempany CM, Zhang E, Hata N. Development and preliminary evaluation of a motorized needle guide template for MRI-guided targeted prostate biopsy. IEEE Trans Biomed Eng. 2013 Nov; 60(11):3019-27. PMID: 23335658; PMCID: PMC3778164.
  26. Tokuda J, Song SE, Tuncali K, Tempany C, Hata N. Configurable automatic detection and registration of fiducial frames for device-to-image registration in MRI-guided prostate interventions. Med Image Comput Comput Assist Interv. 2013; 16(Pt 3):355-62. PMID: 24505781; PMCID: PMC4009697.
  27. Tokuda J, Tuncali K, Iordachita I, Song SE, Fedorov A, Oguro S, Lasso A, Fennessy FM, Tempany CM, Hata N. In-bore setup and software for 3T MRI-guided transperineal prostate biopsy. Phys Med Biol. 2012 Sep 21; 57(18):5823-40. PMID: 22951350; PMCID: PMC3517895.
  28. Tokuda J, Song SE, Fischer GS, Iordachita II, Seifabadi R, Cho NB, Tuncali K, Fichtinger G, Tempany CM, Hata N. Preclinical evaluation of an MRI-compatible pneumatic robot for angulated needle placement in transperineal prostate interventions. Int J Comput Assist Radiol Surg. 2012 Nov; 7(6):949-57. PMID: 22678723; PMCID: PMC3692285.
  29. Seifabadi R, Cho NB, Song SE, Tokuda J, Hata N, Tempany CM, Fichtinger G, Iordachita I. Accuracy study of a robotic system for MRI-guided prostate needle placement. Int J Med Robot. 2013 Sep; 9(3):305-16. PMID: 22678990; PMCID: PMC3772968.
  30. Fedorov A, Tuncali K, Fennessy FM, Tokuda J, Hata N, Wells WM, Kikinis R, Tempany CM. Image registration for targeted MRI-guided transperineal prostate biopsy. J Magn Reson Imaging. 2012 Oct; 36(4):987-92. PMID: 22645031.
    View in: PubMed
  31. Song SE, Hata N, Iordachita I, Fichtinger G, Tempany C, Tokuda J. A workspace-orientated needle-guiding robot for 3T MRI-guided transperineal prostate intervention: evaluation of in-bore workspace and MRI compatibility. Int J Med Robot. 2013 Mar; 9(1):67-74. PMID: 22492680; PMCID: PMC3674858.
  32. Egger J, Tokuda J, Chauvin L, Freisleben B, Nimsky C, Kapur T, Wells W. Integration of the OpenIGTLink network protocol for image-guided therapy with the medical platform MeVisLab. Int J Med Robot. 2012 Sep; 8(3):282-90. PMID: 22374845; PMCID: PMC3405168.
  33. Mamata H, Tokuda J, Gill RR, Padera RF, Lenkinski RE, Sugarbaker DJ, Butler JP, Hatabu H. Clinical application of pharmacokinetic analysis as a biomarker of solitary pulmonary nodules: dynamic contrast-enhanced MR imaging. Magn Reson Med. 2012 Nov; 68(5):1614-22. PMID: 22231729; PMCID: PMC3335927.
  34. Seifabadi R, Song SE, Krieger A, Cho NB, Tokuda J, Fichtinger G, Iordachita I. Robotic system for MRI-guided prostate biopsy: feasibility of teleoperated needle insertion and ex vivo phantom study. Int J Comput Assist Radiol Surg. 2012 Mar; 7(2):181-90. PMID: 21698389; PMCID: PMC3356244.
  35. Tokuda J, Mamata H, Gill RR, Hata N, Kikinis R, Padera RF, Lenkinski RE, Sugarbaker DJ, Hatabu H. Impact of nonrigid motion correction technique on pixel-wise pharmacokinetic analysis of free-breathing pulmonary dynamic contrast-enhanced MR imaging. J Magn Reson Imaging. 2011 Apr; 33(4):968-73. PMID: 21448965; PMCID: PMC3069717.
  36. Song SE, Cho N, Tokuda J, Hata N, Tempany C, Fichtinger G, Iordachita I. Preliminary Evaluation of a MRI-compatible Modular Robotic System for MRI-guided Prostate Interventions. Proc IEEE RAS EMBS Int Conf Biomed Robot Biomechatron. 2010 Sep 26; 2010:796-801. PMID: 21132087.
    View in: PubMed
  37. Tokuda J, Fischer GS, Papademetris X, Yaniv Z, Ibanez L, Cheng P, Liu H, Blevins J, Arata J, Golby AJ, Kapur T, Pieper S, Burdette EC, Fichtinger G, Tempany CM, Hata N. OpenIGTLink: an open network protocol for image-guided therapy environment. Int J Med Robot. 2009 Dec; 5(4):423-34. PMID: 19621334; PMCID: PMC2811069.
  38. Oguro S, Tokuda J, Elhawary H, Haker S, Kikinis R, Tempany CM, Hata N. MRI signal intensity based B-spline nonrigid registration for pre- and intraoperative imaging during prostate brachytherapy. J Magn Reson Imaging. 2009 Nov; 30(5):1052-8. PMID: 19856437; PMCID: PMC2801562.
  39. Tokuda J, Fischer GS, DiMaio SP, Gobbi DG, Csoma C, Mewes PW, Fichtinger G, Tempany CM, Hata N. Integrated navigation and control software system for MRI-guided robotic prostate interventions. Comput Med Imaging Graph. 2010 Jan; 34(1):3-8. PMID: 19699057; PMCID: PMC2815337.
  40. Arata J, Kozuka H, Kim HW, Takesue N, Vladimirov B, Sakaguchi M, Tokuda J, Hata N, Chinzei K, Fujimoto H. Open core control software for surgical robots. Int J Comput Assist Radiol Surg. 2010 May; 5(3):211-20. PMID: 20033506; PMCID: PMC2925237.
  41. Morikawa S, Naka S, Murakami K, Kurumi Y, Shiomi H, Tani T, Haque HA, Tokuda J, Hata N, Inubushi T. Preliminary clinical experiences of a motorized manipulator for magnetic resonance image-guided microwave coagulation therapy of liver tumors. Am J Surg. 2009 Sep; 198(3):340-7. PMID: 19596118.
    View in: PubMed
  42. Tokuda J, Schmitt M, Sun Y, Patz S, Tang Y, Mountford CE, Hata N, Wald LL, Hatabu H. Lung motion and volume measurement by dynamic 3D MRI using a 128-channel receiver coil. Acad Radiol. 2009 Jan; 16(1):22-7. PMID: 19064208; PMCID: PMC2804926.
  43. Fischer GS, Iordachita I, Csoma C, Tokuda J, Mewes PW, Tempany CM, Hata N, Fichtinger G. Pneumatically Operated MRI-Compatible Needle Placement Robot for Prostate Interventions. IEEE Int Conf Robot Autom. 2008 Jun 13; 2008:2489-2495. PMID: 21686038.
    View in: PubMed
  44. Fischer GS, Iordachita I, Csoma C, Tokuda J, Dimaio SP, Tempany CM, Hata N, Fichtinger G. MRI-Compatible Pneumatic Robot for Transperineal Prostate Needle Placement. IEEE ASME Trans Mechatron. 2008 Jun 01; 13(3):295-305. PMID: 21057608.
    View in: PubMed
  45. Gregory S. Fischer, Iulian Iordachita, Csaba Csoma, Junichi Tokuda, Simon P. DiMaio, Clare M. Tempany, Nobuhiko Hata and Gabor Fichtinger . MRI-Compatible Pneumatic Robot for Transperineal Prostate Needle Placement. IEEE / ASME Transactions on Mechatronics. 2008; 13(3):295-305.
  46. Tokuda J, Morikawa S, Haque HA, Tsukamoto T, Matsumiya K, Liao H, Masamune K, Dohi T. Adaptive 4D MR imaging using navigator-based respiratory signal for MRI-guided therapy. Magn Reson Med. 2008 May; 59(5):1051-61. PMID: 18429011; PMCID: PMC3004024.
  47. Hata N, Tokuda J, Hurwitz S, Morikawa S. MRI-compatible manipulator with remote-center-of-motion control. J Magn Reson Imaging. 2008 May; 27(5):1130-8. PMID: 18407542; PMCID: PMC2815332.
  48. Lesniak J, Tokuda J, Kikinis R, Burghart C, Hata N. A device guidance method for organ motion compensation in MRI-guided therapy. Phys Med Biol. 2007 Nov 07; 52(21):6427-38. PMID: 17951853.
    View in: PubMed
  49. Tokuda J, Morikawa S, Dohi T, Hata N. Motion tracking in MR-guided liver therapy by using navigator echoes and projection profile matching. Acad Radiol. 2004 Jan; 11(1):111-20. PMID: 14746411.
    View in: PubMed
  50. Morikawa S, Inubushi T, Kurumi Y, Naka S, Sato K, Demura K, Tani T, Haque HA, Tokuda J, Hata N. Advanced computer assistance for magnetic resonance-guided microwave thermocoagulation of liver tumors. Acad Radiol. 2003 Dec; 10(12):1442-9. PMID: 14697012.
    View in: PubMed
  51. Tokuda J, Hirano M, Tsukamoto T, Dohi T, Hata N. Integration of Projection Profile Matching into Clinical MR Scanner System for Real-time Organ Tracking and Image Registration. In Proceedings of The 6th Annual International Conference on Medical Image Computing and Computer Assisted Intervention - MICCAI 2003. 2003; 311-8.
  52. Morikawa S, Inubushi T, Kurumi Y, Naka S, Sato K, Tani T, Haque HA, Tokuda J, Hata N. New assistive devices for MR-guided microwave thermocoagulation of liver tumors. Acad Radiol. 2003 Feb; 10(2):180-8. PMID: 12583570.
    View in: PubMed
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.