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David Christoper Bragg, Ph.D.

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Confocal Microscope Core (MGH) - Core services (9), Instruments (6) and Software (4)

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Bragg DC, Mangkalaphiban K, Vaine CA, Kulkarni NJ, Shin D, Yadav R, Dhakal J, Ton ML, Cheng A, Russo CT, Ang M, Acuña P, Go C, Franceour TN, Multhaupt-Buell T, Ito N, Müller U, Hendriks WT, Breakefield XO, Sharma N, Ozelius LJ. Disease onset in X-linked dystonia-parkinsonism correlates with expansion of a hexameric repeat within an SVA retrotransposon in TAF1. Proc Natl Acad Sci U S A. 2017 12 19; 114(51):E11020-E11028. PMID: 29229810.
    Citations: 1     Fields:    Translation:HumansCells
  2. Vaine CA, Shin D, Liu C, Hendriks WT, Dhakal J, Shin K, Sharma N, Bragg DC. X-linked Dystonia-Parkinsonism patient cells exhibit altered signaling via nuclear factor-kappa B. Neurobiol Dis. 2017 Apr; 100:108-118. PMID: 28017799.
    Citations: 1     Fields:    Translation:HumansCells
  3. Ito N, Hendriks WT, Dhakal J, Vaine CA, Liu C, Shin D, Shin K, Wakabayashi-Ito N, Dy M, Multhaupt-Buell T, Sharma N, Breakefield XO, Bragg DC. Decreased N-TAF1 expression in X-linked dystonia-parkinsonism patient-specific neural stem cells. Dis Model Mech. 2016 Apr; 9(4):451-62. PMID: 26769797.
    Citations: 6     Fields:    Translation:HumansCells
  4. Vaughn LS, Bragg DC, Sharma N, Camargos S, Cardoso F, Patel RC. Altered activation of protein kinase PKR and enhanced apoptosis in dystonia cells carrying a mutation in PKR activator protein PACT. J Biol Chem. 2015 Sep 11; 290(37):22543-57. PMID: 26231208.
    Citations: 4     Fields:    Translation:HumansCells
  5. Bragg DC, Sharma N. Update on treatments for dystonia. Curr Neurol Neurosci Rep. 2014 Jun; 14(6):454. PMID: 24744022.
    Citations: 2     Fields:    Translation:Humans
  6. Meeker RB, Bragg DC, Poulton W, Hudson L. Transmigration of macrophages across the choroid plexus epithelium in response to the feline immunodeficiency virus. Cell Tissue Res. 2012 Feb; 347(2):443-55. PMID: 22281685; PMCID: PMC3785230.
    Citations: 5     Fields:    Translation:AnimalsCells
  7. Sengel C, Gavarini S, Sharma N, Ozelius LJ, Bragg DC. Dimerization of the DYT6 dystonia protein, THAP1, requires residues within the coiled-coil domain. J Neurochem. 2011 Sep; 118(6):1087-100. PMID: 21752024; PMCID: PMC3166381.
    Citations: 12     Fields:    Translation:HumansCells
  8. Bragg DC, Armata IA, Nery FC, Breakefield XO, Sharma N. Molecular pathways in dystonia. Neurobiol Dis. 2011 May; 42(2):136-47. PMID: 21134457; PMCID: PMC3073693.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  9. Orlando LR, Ayala R, Kett LR, Curley AA, Duffner J, Bragg DC, Tsai LH, Dunah AW, Young AB. Phosphorylation of the homer-binding domain of group I metabotropic glutamate receptors by cyclin-dependent kinase 5. J Neurochem. 2009 Jul; 110(2):557-69. PMID: 19457112.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  10. Hewett JW, Zeng J, Niland BP, Bragg DC, Breakefield XO. Dystonia-causing mutant torsinA inhibits cell adhesion and neurite extension through interference with cytoskeletal dynamics. Neurobiol Dis. 2006 Apr; 22(1):98-111. PMID: 16361107.
    Citations: 51     Fields:    Translation:HumansCells
  11. Hudson LC, Bragg DC, Tompkins MB, Meeker RB. Astrocytes and microglia differentially regulate trafficking of lymphocyte subsets across brain endothelial cells. Brain Res. 2005 Oct 05; 1058(1-2):148-60. PMID: 16137663.
    Citations: 15     Fields:    Translation:AnimalsCells
  12. Sharma N, Baxter MG, Petravicz J, Bragg DC, Schienda A, Standaert DG, Breakefield XO. Impaired motor learning in mice expressing torsinA with the DYT1 dystonia mutation. J Neurosci. 2005 Jun 01; 25(22):5351-5. PMID: 15930383.
    Citations: 53     Fields:    Translation:HumansAnimalsCells
  13. Bragg DC, Kaufman CA, Kock N, Breakefield XO. Inhibition of N-linked glycosylation prevents inclusion formation by the dystonia-related mutant form of torsinA. Mol Cell Neurosci. 2004 Dec; 27(4):417-26. PMID: 15555920.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  14. Meeker RB, Boles JC, Bragg DC, Robertson K, Hall C. Development of neuronal sensitivity to toxins in cerebrospinal fluid from HIV-type 1-infected individuals. AIDS Res Hum Retroviruses. 2004 Oct; 20(10):1072-86. PMID: 15585098.
    Citations: 5     Fields:    Translation:AnimalsCells
  15. Bragg DC, Slater DJ, Breakefield XO. TorsinA and early-onset torsion dystonia. Adv Neurol. 2004; 94:87-93. PMID: 14509659.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  16. Bragg DC, Camp SM, Kaufman CA, Wilbur JD, Boston H, Schuback DE, Hanson PI, Sena-Esteves M, Breakefield XO. Perinuclear biogenesis of mutant torsin-A inclusions in cultured cells infected with tetracycline-regulated herpes simplex virus type 1 amplicon vectors. Neuroscience. 2004; 125(3):651-61. PMID: 15099679.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  17. Bragg DC, Hudson LC, Liang YH, Tompkins MB, Fernandes A, Meeker RB. Choroid plexus macrophages proliferate and release toxic factors in response to feline immunodeficiency virus. J Neurovirol. 2002 Jun; 8(3):225-39. PMID: 12053277.
    Citations: 11     Fields:    Translation:AnimalsCells
  18. Bragg DC, Childers TA, Tompkins MB, Tompkins WA, Meeker RB. Infection of the choroid plexus by feline immunodeficiency virus. J Neurovirol. 2002 Jun; 8(3):211-24. PMID: 12053276.
    Citations: 12     Fields:    Translation:AnimalsCells
  19. Bragg DC, Boles JC, Meeker RB. Destabilization of neuronal calcium homeostasis by factors secreted from choroid plexus macrophage cultures in response to feline immunodeficiency virus. Neurobiol Dis. 2002 Mar; 9(2):173-86. PMID: 11895370.
    Citations: 6     Fields:    Translation:AnimalsCells
  20. Meeker RB, Azuma Y, Bragg DC, English RV, Tompkins M. Microglial proliferation in cortical neural cultures exposed to feline immunodeficiency virus. J Neuroimmunol. 1999 Nov 01; 101(1):15-26. PMID: 10580809.
    Citations: 7     Fields:    Translation:AnimalsCells
  21. Bragg DC, Meeker RB, Duff BA, English RV, Tompkins MB. Neurotoxicity of FIV and FIV envelope protein in feline cortical cultures. Brain Res. 1999 Jan 23; 816(2):431-7. PMID: 9878865.
    Citations: 9     Fields:    Translation:AnimalsCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.