Juan M. Melero-Martin, Ph.D.
Title Associate Professor of Surgery Institution Boston Children's Hospital Address Childrens Hospital
Enders 349
300 Longwood Ave
Boston MA 02115
|
|
Overview
Stem cell transplantation and tissue engineering hold great promise in regenerative medicine. However, engrafting stem cells and generating tissues with stable vascular beds remain major challenges. Our laboratory is interested in understanding mechanisms of vascular network formation and stem cell engraftment using human stem and progenitor cells. Our long-term goal is to develop novel therapeutic strategies in regenerative medicine. Current projects in the lab are focused on:
1) Endothelial progenitor cell biology and therapeutic potential
2) Bioengineering vascular networks
3) Genetically-engineered vasculature for drug delivery
Please visit our website for more information:
meleromartinlab.com
Research
The research activities and funding listed below are automatically derived from
NIH ExPORTER and other sources, which might result in incorrect or missing items.
Faculty can
login
to make corrections and additions.
-
R01AR080086
(MELERO-MARTIN, JUAN M)
Aug 10, 2022 - May 31, 2027
Human endothelial cell regulation of ossification
Role: Principal Investigator
-
R01HL151450
(MELERO-MARTIN, JUAN M;PU, WILLIAM TSWENCHING)
Feb 15, 2021 - Jan 31, 2025
Regulation of endothelial cell specification
Role: Co-Principal Investigator
-
R01HL152133
(MELERO-MARTIN, JUAN M)
Dec 20, 2020 - Nov 30, 2024
Enhancing endothelial cell engraftment via transplantation of exogenous mitochondria
Role: Principal Investigator
-
R21AI123883
(MELERO-MARTIN, JUAN M)
Aug 19, 2016 - Jul 31, 2018
Host neutrophils as direct mediators of tissue graft revascularization
Role: Principal Investigator
-
R01AR069038
(MELERO-MARTIN, JUAN M)
May 16, 2016 - Apr 30, 2021
Vascular niche bioengineering for human bone regeneration
Role: Principal Investigator
-
R01HL128452
(MA, MINGLIN ;MELERO-MARTIN, JUAN M)
Aug 15, 2015 - Apr 30, 2025
Vascular networks genetically engineered for protein drug delivery
Role: Principal Investigator
-
R00EB009096
(MELERO-MARTIN, JUAN M)
Aug 15, 2009 - Jul 31, 2014
Engineering vascularized tissue in vivo using postnatal progenitor cells
Role: Principal Investigator
-
K99EB009096
(MELERO-MARTIN, JUAN M)
Aug 15, 2009 - Jul 31, 2011
Engineering vascularized tissue in vivo using postnatal progenitor cells
Role: Principal Investigator
Featured Content
Bibliographic
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.