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profileLaura Edith Simons, Ph.D.

TitleAssociate Professor of Psychology in the Department of Psychiatry
InstitutionBoston Children's Hospital
DepartmentPsychiatry
AddressBoston Children's Hospital
Pain Treatment Service
21 Autumn St., Office 110.3
Boston MA 02215
Phone617/919-4677
Fax617/730-0759
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Other Positions
TitleAssociate Professor of Anaesthesia
InstitutionBoston Children's Hospital
DepartmentAnaesthesia


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R01HD083270     (SIMONS, LAURA E)Dec 21, 2015 - Aug 31, 2020
NIH/NICHD
Fear learning in adolescents with chronic pain: Neural and behavioral mechanisms
Role: Principal Investigator

K23HD067202     (SIMONS, LAURA E)Mar 1, 2011 - Feb 29, 2016
NIH/NICHD
A neuroimaging perspective of pain-related fear in children with chronic pain
Role: Principal Investigator

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Simons LE, Goubert L, Vervoort T, Borsook D. Circles of engagement: Childhood pain and parent brain. Neurosci Biobehav Rev. 2016 Sep; 68:537-46. PMID: 27320958.
    View in: PubMed
  2. Chow ET, Otis JD, Simons LE. The Longitudinal Impact of Parent Distress and Behavior on Functional Outcomes Among Youth With Chronic Pain. J Pain. 2016 Jun; 17(6):729-38. PMID: 26993960.
    View in: PubMed
  3. Simons LE. Fear of pain in children and adolescents with neuropathic pain and complex regional pain syndrome. Pain. 2016 Feb; 157 Suppl 1:S90-7. PMID: 26785161.
    View in: PubMed
  4. Simons LE, Erpelding N, Hernandez JM, Serrano P, Zhang K, Lebel AA, Sethna NF, Berde CB, Prabhu SP, Becerra L, Borsook D. Fear and Reward Circuit Alterations in Pediatric CRPS. Front Hum Neurosci. 2015; 9:703. PMID: 26834606.
    View in: PubMed
  5. Simons LE, Basch MC. State of the art in biobehavioral approaches to the management of chronic pain in childhood. Pain Manag. 2016; 6(1):49-61. PMID: 26678858.
    View in: PubMed
  6. Basch MC, Chow ET, Logan DE, Schechter NL, Simons LE. Perspectives on the clinical significance of functional pain syndromes in children. J Pain Res. 2015; 8:675-86. PMID: 26504406; PMCID: PMC4605245.
  7. Simons LE, Smith A, Ibagon C, Coakley R, Logan DE, Schechter N, Borsook D, Hill JC. Pediatric Pain Screening Tool: rapid identification of risk in youth with pain complaints. Pain. 2015 Aug; 156(8):1511-8. PMID: 25906349; PMCID: PMC4504741 [Available on 08/01/16].
  8. Smith AM, Sieberg CB, Odell S, Randall E, Simons LE. Living Life With My Child's Pain: The Parent Pain Acceptance Questionnaire (PPAQ). Clin J Pain. 2015 Jul; 31(7):633-41. PMID: 25119514; PMCID: PMC4326631 [Available on 07/01/16].
  9. Hechler T, Kanstrup M, Holley AL, Simons LE, Wicksell R, Hirschfeld G, Zernikow B. Systematic Review on Intensive Interdisciplinary Pain Treatment of Children With Chronic Pain. Pediatrics. 2015 Jul; 136(1):115-27. PMID: 26101358.
    View in: PubMed
  10. Cousins LA, Kalapurakkel S, Cohen LL, Simons LE. Topical Review: Resilience Resources and Mechanisms in Pediatric Chronic Pain. J Pediatr Psychol. 2015 Oct; 40(9):840-5. PMID: 25979085; PMCID: PMC4643616 [Available on 10/01/16].
  11. Simons LE, Sieberg CB. Parents--to help or hinder pain memories in children. Pain. 2015 May; 156(5):761-2. PMID: 25734996; PMCID: PMC4405457 [Available on 05/01/16].
  12. Loiselle KA, Gutierrez-Colina AM, Eaton CK, Simons LE, Devine KA, Mee LL, Blount RL. Longitudinal stability of medication adherence among adolescent solid organ transplant recipients. Pediatr Transplant. 2015 Jun; 19(4):428-35. PMID: 25879392.
    View in: PubMed
  13. Simons LE, Smith A, Kaczynski K, Basch M. Living in fear of your child's pain: the Parent Fear of Pain Questionnaire. Pain. 2015 Apr; 156(4):694-702. PMID: 25630026; PMCID: PMC4366345 [Available on 04/01/16].
  14. Wu YP, Hung M, Franklin JD, Samhouri M, Simons LE, Amylon MD. Validation of a measure of children's perceptions of their oncology camp experience: a national study. Psychooncology. 2016 Jan; 25(1):112-4. PMID: 25736248.
    View in: PubMed
  15. Erpelding N, Simons L, Lebel A, Serrano P, Pielech M, Prabhu S, Becerra L, Borsook D. Rapid treatment-induced brain changes in pediatric CRPS. Brain Struct Funct. 2016 Mar; 221(2):1095-111. PMID: 25515312.
    View in: PubMed
  16. Eaton CK, Lee JL, Simons LE, Devine KA, Mee LL, Blount RL. Clinical cutoffs for adherence barriers in solid organ transplant recipients: how many is too many? J Pediatr Psychol. 2015 May; 40(4):431-41. PMID: 25418331.
    View in: PubMed
  17. Kalapurakkel S, Carpino EA, Lebel A, Simons LE. "Pain Can't Stop Me": Examining Pain Self-Efficacy and Acceptance as Resilience Processes Among Youth With Chronic Headache. J Pediatr Psychol. 2015 Oct; 40(9):926-33. PMID: 25324532; PMCID: PMC4592326 [Available on 10/01/16].
  18. Pielech M, Ryan M, Logan D, Kaczynski K, White MT, Simons LE. Pain catastrophizing in children with chronic pain and their parents: proposed clinical reference points and reexamination of the Pain Catastrophizing Scale measure. Pain. 2014 Nov; 155(11):2360-7. PMID: 25180013; PMCID: PMC4253605.
  19. Becerra L, Sava S, Simons LE, Drosos AM, Sethna N, Berde C, Lebel AA, Borsook D. Intrinsic brain networks normalize with treatment in pediatric complex regional pain syndrome. Neuroimage Clin. 2014; 6:347-69. PMID: 25379449; PMCID: PMC4218937.
  20. Cappucci S, Simons LE. Anxiety sensitivity and fear of pain in paediatric headache patients. Eur J Pain. 2015 Feb; 19(2):246-52. PMID: 24925092; PMCID: PMC4265313 [Available on 02/01/16].
  21. Simons LE, Pielech M, Erpelding N, Linnman C, Moulton E, Sava S, Lebel A, Serrano P, Sethna N, Berde C, Becerra L, Borsook D. The responsive amygdala: treatment-induced alterations in functional connectivity in pediatric complex regional pain syndrome. Pain. 2014 Sep; 155(9):1727-42. PMID: 24861582; PMCID: PMC4157948.
  22. Lee JL, Eaton C, Gutiérrez-Colina AM, Devine K, Simons LE, Mee L, Blount RL. Longitudinal stability of specific barriers to medication adherence. J Pediatr Psychol. 2014 Aug; 39(7):667-76. PMID: 24824613.
    View in: PubMed
  23. Simons LE, Pielech M, Cappucci S, Lebel A. Fear of pain in pediatric headache. Cephalalgia. 2015 Jan; 35(1):36-44. PMID: 24812036; PMCID: PMC4224998 [Available on 01/01/16].
  24. Carpino E, Segal S, Logan D, Lebel A, Simons LE. The interplay of pain-related self-efficacy and fear on functional outcomes among youth with headache. J Pain. 2014 May; 15(5):527-34. PMID: 24462790; PMCID: PMC4012017.
  25. Simons LE, Elman I, Borsook D. Psychological processing in chronic pain: a neural systems approach. Neurosci Biobehav Rev. 2014 Feb; 39:61-78. PMID: 24374383; PMCID: PMC3944001.
  26. Sieberg CB, Simons LE, Edelstein MR, DeAngelis MR, Pielech M, Sethna N, Hresko MT. Pain prevalence and trajectories following pediatric spinal fusion surgery. J Pain. 2013 Dec; 14(12):1694-702. PMID: 24290449; PMCID: PMC3873090.
  27. Erpelding N, Sava S, Simons LE, Lebel A, Serrano P, Becerra L, Borsook D. Habenula functional resting-state connectivity in pediatric CRPS. J Neurophysiol. 2014 Jan; 111(2):239-47. PMID: 24155006; PMCID: PMC3921385.
  28. Simons LE, Sieberg CB, Coakley RM. Patients with pain are not all the same: considering fear of pain and other individual factors in treatment. Pain Manag. 2013 Mar; 3(2):87-9. PMID: 24645990; PMCID: PMC4060630.
  29. Reed-Knight B, Loiselle KA, Devine KA, Simons LE, Mee LL, Blount RL. Health-related quality of life and perceived need for mental health services in adolescent solid organ transplant recipients. J Clin Psychol Med Settings. 2013 Mar; 20(1):88-96. PMID: 22581075; PMCID: PMC3916010.
  30. Simons LE. Growing up in the society of pediatric psychology: reflections of an early career psychologist. J Pediatr Psychol. 2013 Mar; 38(2):132-4. PMID: 23241351; PMCID: PMC3695660.
  31. Logan DE, Carpino EA, Chiang G, Condon M, Firn E, Gaughan VJ, Hogan M, Leslie DS, Olson K, Sager S, Sethna N, Simons LE, Zurakowski D, Berde CB. A day-hospital approach to treatment of pediatric complex regional pain syndrome: initial functional outcomes. Clin J Pain. 2012 Nov-Dec; 28(9):766-74. PMID: 22688602; PMCID: PMC3884573.
  32. Simons LE, Sieberg CB, Pielech M, Conroy C, Logan DE. What does it take? Comparing intensive rehabilitation to outpatient treatment for children with significant pain-related disability. J Pediatr Psychol. 2013 Mar; 38(2):213-23. PMID: 23104827; PMCID: PMC3695659.
  33. Simons LE, Moulton EA, Linnman C, Carpino E, Becerra L, Borsook D. The human amygdala and pain: evidence from neuroimaging. Hum Brain Mapp. 2014 Feb; 35(2):527-38. PMID: 23097300; PMCID: PMC3920543.
  34. Simons LE, Kaczynski KJ, Conroy C, Logan DE. Fear of pain in the context of intensive pain rehabilitation among children and adolescents with neuropathic pain: associations with treatment response. J Pain. 2012 Dec; 13(12):1151-61. PMID: 23085089; PMCID: PMC3508158.
  35. Simons LE, Kaczynski KJ. The Fear Avoidance model of chronic pain: examination for pediatric application. J Pain. 2012 Sep; 13(9):827-35. PMID: 22832693; PMCID: PMC3438388.
  36. Logan DE, Conroy C, Sieberg CB, Simons LE. Changes in willingness to self-manage pain among children and adolescents and their parents enrolled in an intensive interdisciplinary pediatric pain treatment program. Pain. 2012 Sep; 153(9):1863-70. PMID: 22749194; PMCID: PMC3884572.
  37. Simons LE, Sieberg CB, Claar RL. Anxiety and impairment in a large sample of children and adolescents with chronic pain. Pain Res Manag. 2012 Mar-Apr; 17(2):93-7. PMID: 22518371; PMCID: PMC3393050.
  38. Logan DE, Simons LE, Carpino EA. Too sick for school? Parent influences on school functioning among children with chronic pain. Pain. 2012 Feb; 153(2):437-43. PMID: 22169177; PMCID: PMC3884564.
  39. Guite JW, Logan DE, Simons LE, Blood EA, Kerns RD. Readiness to change in pediatric chronic pain: initial validation of adolescent and parent versions of the Pain Stages of Change Questionnaire. Pain. 2011 Oct; 152(10):2301-11. PMID: 21802852; PMCID: PMC3222695.
  40. Simons LE, Sieberg CB, Kaczynski KJ. Measuring parent beliefs about child acceptance of pain: a preliminary validation of the Chronic Pain Acceptance Questionnaire, parent report. Pain. 2011 Oct; 152(10):2294-300. PMID: 21783324; PMCID: PMC3557831.
  41. Sieberg CB, Williams S, Simons LE. Do parent protective responses mediate the relation between parent distress and child functional disability among children with chronic pain? J Pediatr Psychol. 2011 Oct; 36(9):1043-51. PMID: 21742755.
    View in: PubMed
  42. Kaczynski KJ, Simons LE, Claar RL. Anxiety, coping, and disability: a test of mediation in a pediatric chronic pain sample. J Pediatr Psychol. 2011 Sep; 36(8):932-41. PMID: 21551124.
    View in: PubMed
  43. Claar RL, Simons LE. Adolescents' pain coping profiles: expectations for treatment, functional outcomes and adherence to psychological treatment recommendations. Pain Res Manag. 2011 May-Jun; 16(3):192-6. PMID: 21766070; PMCID: PMC3198106.
  44. Simons LE, Sieberg CB, Carpino E, Logan D, Berde C. The Fear of Pain Questionnaire (FOPQ): assessment of pain-related fear among children and adolescents with chronic pain. J Pain. 2011 Jun; 12(6):677-86. PMID: 21354866.
    View in: PubMed
  45. Devine KA, Reed-Knight B, Loiselle KA, Simons LE, Mee LL, Blount RL. Predictors of long-term health-related quality of life in adolescent solid organ transplant recipients. J Pediatr Psychol. 2011 Sep; 36(8):891-901. PMID: 21343144; PMCID: PMC3935000.
  46. Devine KA, Reed-Knight B, Simons LE, Mee LL, Blount RL. Prospective comparison of parent and adolescent report of health-related quality of life in adolescent solid organ transplant recipients. Pediatr Transplant. 2010 Dec; 14(8):1000-6. PMID: 20846240.
    View in: PubMed
  47. Simons LE, Logan DE, Chastain L, Cerullo M. Engagement in multidisciplinary interventions for pediatric chronic pain: parental expectations, barriers, and child outcomes. Clin J Pain. 2010 May; 26(4):291-9. PMID: 20393263.
    View in: PubMed
  48. Simons LE, McCormick ML, Devine K, Blount RL. Medication barriers predict adolescent transplant recipients' adherence and clinical outcomes at 18-month follow-up. J Pediatr Psychol. 2010 Oct; 35(9):1038-48. PMID: 20410021.
    View in: PubMed
  49. Logan DE, Simons LE. Development of a group intervention to improve school functioning in adolescents with chronic pain and depressive symptoms: a study of feasibility and preliminary efficacy. J Pediatr Psychol. 2010 Sep; 35(8):823-36. PMID: 20167628.
    View in: PubMed
  50. Simons LE, Logan DE, Chastain L, Stein M. The relation of social functioning to school impairment among adolescents with chronic pain. Clin J Pain. 2010 Jan; 26(1):16-22. PMID: 20026948.
    View in: PubMed
  51. Logan DE, Simons LE, Kaczynski KJ. School functioning in adolescents with chronic pain: the role of depressive symptoms in school impairment. J Pediatr Psychol. 2009 Sep; 34(8):882-92. PMID: 19181819.
    View in: PubMed
  52. Claar RL, Baber KF, Simons LE, Logan DE, Walker LS. Pain coping profiles in adolescents with chronic pain. Pain. 2008 Nov 30; 140(2):368-75. PMID: 18938032; PMCID: PMC3100727.
  53. Simons LE, Gilleland J, Blount RL, Amaral S, Berg A, Mee LL. Multidimensional Adherence Classification System: initial development with adolescent transplant recipients. Pediatr Transplant. 2009 Aug; 13(5):590-8. PMID: 18992064.
    View in: PubMed
  54. Simons LE, McCormick ML, Mee LL, Blount RL. Parent and patient perspectives on barriers to medication adherence in adolescent transplant recipients. Pediatr Transplant. 2009 May; 13(3):338-47. PMID: 18433413.
    View in: PubMed
  55. Simons LE, Gilleland J, Hubbard McDanel A, Blount RL, & Campbell, R. . Initial development of the Pediatric Camp Outcome Measure . Children’s Health Care. 2008; 37:158-169.
  56. Simons LE, Claar RL, Logan DL. Chronic pain in adolescence: parental responses, adolescent coping, and their impact on adolescent's pain behaviors. J Pediatr Psychol. 2008 Sep; 33(8):894-904. PMID: 18375447; PMCID: PMC2493514.
  57. Blount RL, Devine KA, Cheng PS, Simons LE, Hayutin L. The impact of adult behaviors and vocalizations on infant distress during immunizations. J Pediatr Psychol. 2008 Nov-Dec; 33(10):1163-74. PMID: 18375966.
    View in: PubMed
  58. Simons LE, Anglin G, Warshaw BL, Mahle WT, Vincent RN, Blount RL. Understanding the pathway between the transplant experience and health-related quality of life outcomes in adolescents. Pediatr Transplant. 2008 Mar; 12(2):187-93. PMID: 18307667.
    View in: PubMed
  59. Logan DE, Simons LE, Stein MJ, Chastain L. School impairment in adolescents with chronic pain. J Pain. 2008 May; 9(5):407-16. PMID: 18255341.
    View in: PubMed
  60. Claar RL, Simons LE, Logan DE. Parental response to children's pain: the moderating impact of children's emotional distress on symptoms and disability. Pain. 2008 Aug 15; 138(1):172-9. PMID: 18221837.
    View in: PubMed
  61. Scharff L & Simons L. Functional Abdominal Pain. Pain in Children: A Practical Guide for Primary Care. Eds Walco GA, Goldschneider KR. 2008.
  62. Simons L, Ingerski LM, Janicke DM. Social support, coping, and psychological distress in mothers and fathers of pediatric transplant candidates: a pilot study. Pediatr Transplant. 2007 Nov; 11(7):781-7. PMID: 17910657.
    View in: PubMed
  63. Simons LE, Blount RL, Campbell R, Hubbard A, Goodwin B, Devine K, Benoit M. Decreases in anxiety associated with participation in a camp for children with cardiac defects. Cardiol Young. 2007 Dec; 17(6):631-7. PMID: 17961266.
    View in: PubMed
  64. Blount RL, Simons LE, Devine KA, Jaaniste T, Cohen LL, Chambers CT, Hayutin LG. Evidence-based assessment of coping and stress in pediatric psychology. J Pediatr Psychol. 2008 Oct; 33(9):1021-45. PMID: 17938147; PMCID: PMC2639500.
  65. Ohleyer V, Freddo M, Bagner DM, Simons LE, Geffken GR, Silverstein JH, Storch EA. Disease-related stress in parents of children who are overweight: relations with parental anxiety and childhood psychosocial functioning. J Child Health Care. 2007 Jun; 11(2):132-42. PMID: 17494987.
    View in: PubMed
  66. Simons LE, Blount RL. Identifying barriers to medication adherence in adolescent transplant recipients. J Pediatr Psychol. 2007 Aug; 32(7):831-44. PMID: 17522111.
    View in: PubMed
  67. Storch EA, Lack CW, Simons LE, Goodman WK, Murphy TK, Geffken GR. A measure of functional impairment in youth with Tourette's syndrome. J Pediatr Psychol. 2007 Sep; 32(8):950-9. PMID: 17522110.
    View in: PubMed
  68. Kendrick T, Simons L, Mynors-Wallis L, Gray A, Lathlean J, Pickering R, Harris S, Rivero-Arias O, Gerard K, Thompson C. Cost-effectiveness of referral for generic care or problem-solving treatment from community mental health nurses, compared with usual general practitioner care for common mental disorders: Randomised controlled trial. Br J Psychiatry. 2006 Jul; 189:50-9. PMID: 16816306.
    View in: PubMed
  69. Kendrick T, Simons L, Mynors-Wallis L, Gray A, Lathlean J, Pickering R, Harris S, Rivero-Arias O, Gerard K, Thompson C. A trial of problem-solving by community mental health nurses for anxiety, depression and life difficulties among general practice patients. The CPN-GP study. Health Technol Assess. 2005 Sep; 9(37):1-104, iii. PMID: 16153354.
    View in: PubMed
  70. Simons, L.E., Hubbard, A., Campbell, R.M., & Blount, R.L. . Reductions in parental separation anxiety and self-reported anxiety in pediatric heart patients who attended a one-week pediatric camp. . Cardiology in the Young. 2005; 15:95-108.
  71. Seri, L., Heimler, E., Benoit-Ratcliff, M., Simons, L., & Blount, R. . Development of the child-adult medical procedure interaction scale-infant form. Journal of Developmental and Behavioral Pediatrics. 2003; 24:391.
  72. Patterson, S.M., Simons, L., France, C.R., & Tulodzieski, B. Relationship between hydration status and cardiovascular reactivity: Physiological versus psychological challenge. Psychophysiology. 2001; 38:S75.
  73. France, C.R., Simons, L., Patterson, S.M., & Tulodzieski, B. Vasovagal reactions to a surgery film: Physiological and psychological concomitants. Psychophysiology. 2001; 38:S42.
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