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Keywords
Last Name
Institution

Ralph Weissleder, PH.D., M.D.

TitleThrall Family Professor of Radiology
InstitutionMassachusetts General Hospital
DepartmentRadiology
AddressMassachusetts General Hospital
Center for Systems Biology, Rm 8228
185 Cambridge St
Boston MA 02114
Phone617/726-8226
Fax617/726-5708
vCardDownload vCard (login for email)
Other Positions
TitleProfessor of Systems Biology
InstitutionMassachusetts General Hospital
DepartmentSystems Biology


 Mentoring 
 completed student projects
Imaging of PARP1-overexpressing Cancers with Novel Radiotracer 18F-AZD2281
Summer, 06/20/11 - 08/12/11

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Shen K, Luk S, Hicks DF, Elman JS, Bohr S, Iwamoto Y, Murray R, Pena K, Wang F, Seker E, Weissleder R, Yarmush ML, Toner M, Sgroi D, Parekkadan B. Resolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays. Nat Commun. 2014; 5:5662.
    View in: PubMed
  2. Fu W, Farache J, Clardy SM, Hattori K, Mander P, Lee K, Rioja I, Weissleder R, Prinjha RK, Benoist C, Mathis D. Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and ß cells. Elife. 2014; 3.
    View in: PubMed
  3. Laughney AM, Kim E, Sprachman MM, Miller MA, Kohler RH, Yang KS, Orth JD, Mitchison TJ, Weissleder R. Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin. Sci Transl Med. 2014 Nov 5; 6(261):261ra152.
    View in: PubMed
  4. Giedt RJ, Sprachman MM, Yang KS, Weissleder R. Imaging cellular distribution of bcl inhibitors using small molecule drug conjugates. Bioconjug Chem. 2014 Nov 19; 25(11):2081-5.
    View in: PubMed
  5. Taqueti VR, Di Carli MF, Jerosch-Herold M, Sukhova GK, Murthy VL, Folco EJ, Kwong RY, Ozaki CK, Belkin M, Nahrendorf M, Weissleder R, Libby P. Increased microvascularization and vessel permeability associate with active inflammation in human atheromata. Circ Cardiovasc Imaging. 2014 Nov; 7(6):920-9.
    View in: PubMed
  6. Dubach JM, Vinegoni C, Weissleder R. Steady state anisotropy two-photon microscopy resolves multiple, spectrally similar fluorophores, enabling in vivo multilabel imaging. Opt Lett. 2014 Aug 1; 39(15):4482-5.
    View in: PubMed
  7. Hara T, Truelove J, Tawakol A, Wojtkiewicz GR, Hucker WJ, MacNabb MH, Brownell AL, Jokivarsi K, Kessinger CW, Jaff MR, Henke PK, Weissleder R, Jaffer FA. 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Enables the Detection of Recurrent Same-Site Deep Vein Thrombosis by Illuminating Recently Formed, Neutrophil-Rich Thrombus. Circulation. 2014 Sep 23; 130(13):1044-52.
    View in: PubMed
  8. Aguirre AD, Vinegoni C, Sebas M, Weissleder R. Intravital imaging of cardiac function at the single-cell level. Proc Natl Acad Sci U S A. 2014 Aug 5; 111(31):11257-62.
    View in: PubMed
  9. Stangenberg L, Burzyn D, Binstadt BA, Weissleder R, Mahmood U, Benoist C, Mathis D. Denervation protects limbs from inflammatory arthritis via an impact on the microvasculature. Proc Natl Acad Sci U S A. 2014 Aug 5; 111(31):11419-24.
    View in: PubMed
  10. Heidt T, Sager HB, Courties G, Dutta P, Iwamoto Y, Zaltsman A, von Zur Muhlen C, Bode C, Fricchione GL, Denninger J, Lin CP, Vinegoni C, Libby P, Swirski FK, Weissleder R, Nahrendorf M. Chronic variable stress activates hematopoietic stem cells. Nat Med. 2014 Jul; 20(7):754-8.
    View in: PubMed
  11. Issadore D, Park YI, Shao H, Min C, Lee K, Liong M, Weissleder R, Lee H. Magnetic sensing technology for molecular analyses. Lab Chip. 2014 Jun 17; 14(14):2385-97.
    View in: PubMed
  12. Meimetis LG, Carlson JC, Giedt RJ, Kohler RH, Weissleder R. Ultrafluorogenic coumarin-tetrazine probes for real-time biological imaging. Angew Chem Int Ed Engl. 2014 Jul 14; 53(29):7531-4.
    View in: PubMed
  13. Dubach JM, Vinegoni C, Mazitschek R, Fumene Feruglio P, Cameron LA, Weissleder R. In vivo imaging of specific drug-target binding at subcellular resolution. Nat Commun. 2014; 5:3946.
    View in: PubMed
  14. Sprachman MM, Laughney AM, Kohler RH, Weissleder R. In Vivo Imaging of Multidrug Resistance Using a Third Generation MDR1 Inhibitor. Bioconjug Chem. 2014 Jun 18; 25(6):1137-42.
    View in: PubMed
  15. Weber GF, Chousterman BG, Hilgendorf I, Robbins CS, Theurl I, Gerhardt LM, Iwamoto Y, Quach TD, Ali M, Chen JW, Rothstein TL, Nahrendorf M, Weissleder R, Swirski FK. Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis. J Exp Med. 2014 Jun 2; 211(6):1243-56.
    View in: PubMed
  16. Heidt T, Courties G, Dutta P, Sager HB, Sebas M, Iwamoto Y, Sun Y, Da Silva N, Panizzi P, van der Lahn AM, Swirski FK, Weissleder R, Nahrendorf M. Differential contribution of monocytes to heart macrophages in steady-state and after myocardial infarction. Circ Res. 2014 Jul 7; 115(2):284-95.
    View in: PubMed
  17. Turetsky A, Kim E, Kohler RH, Miller MA, Weissleder R. Single cell imaging of Bruton's tyrosine kinase using an irreversible inhibitor. Sci Rep. 2014; 4:4782.
    View in: PubMed
  18. Morton AM, Sefik E, Upadhyay R, Weissleder R, Benoist C, Mathis D. Endoscopic photoconversion reveals unexpectedly broad leukocyte trafficking to and from the gut. Proc Natl Acad Sci U S A. 2014 May 6; 111(18):6696-701.
    View in: PubMed
  19. Im H, Shao H, Park YI, Peterson VM, Castro CM, Weissleder R, Lee H. Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor. Nat Biotechnol. 2014 May; 32(5):490-5.
    View in: PubMed
  20. Zeglis BM, Emmetiere F, Pillarsetty N, Weissleder R, Lewis JS, Reiner T. Building Blocks for the Construction of Bioorthogonally Reactive Peptides via Solid-Phase Peptide Synthesis. ChemistryOpen. 2014 Apr; 3(2):48-53.
    View in: PubMed
  21. Lee S, Vinegoni C, Sebas M, Weissleder R. Automated motion artifact removal for intravital microscopy, without a priori information. Sci Rep. 2014; 4:4507.
    View in: PubMed
  22. Kim E, Yang KS, Giedt RJ, Weissleder R. Red Si-rhodamine drug conjugates enable imaging in GFP cells. Chem Commun (Camb). 2014 May 4; 50(34):4504-7.
    View in: PubMed
  23. Winkler DA, Burden FR, Yan B, Weissleder R, Tassa C, Shaw S, Epa VC. Modelling and predicting the biological effects of nanomaterials. SAR QSAR Environ Res. 2014 Feb; 25(2):161-72.
    View in: PubMed
  24. Hilgendorf I, Gerhardt LM, Tan TC, Winter C, Holderried TA, Chousterman BG, Iwamoto Y, Liao R, Zirlik A, Scherer-Crosbie M, Hedrick CC, Libby P, Nahrendorf M, Weissleder R, Swirski FK. Ly-6Chigh Monocytes Depend on Nr4a1 to Balance Both Inflammatory and Reparative Phases in the Infarcted Myocardium. Circ Res. 2014 May 9; 114(10):1611-22.
    View in: PubMed
  25. Keliher EJ, Klubnick JA, Reiner T, Mazitschek R, Weissleder R. Efficient Acid-Catalyzed (18) F/(19) F Fluoride Exchange of BODIPY Dyes. ChemMedChem. 2014 Jul; 9(7):1368-73.
    View in: PubMed
  26. Elman JS, Murray RM, Wang F, Shen K, Gao S, Conway KE, Yarmush ML, Tannous BA, Weissleder R, Parekkadan B. Pharmacokinetics of natural and engineered secreted factors delivered by mesenchymal stromal cells. PLoS One. 2014; 9(2):e89882.
    View in: PubMed
  27. Thurber GM, Reiner T, Yang KS, Kohler RH, Weissleder R. Effect of Small-Molecule Modification on Single-Cell Pharmacokinetics of PARP Inhibitors. Mol Cancer Ther. 2014 Apr; 13(4):986-95.
    View in: PubMed
  28. Liong M, Im H, Majmudar MD, Aguirre AD, Sebas M, Lee H, Weissleder R. Magnetic Ligation Method for Quantitative Detection of MicroRNAs. Adv Healthc Mater. 2014 Jul; 3(7):1015-9.
    View in: PubMed
  29. Miller MA, Askevold B, Yang KS, Kohler RH, Weissleder R. Platinum compounds for high-resolution in vivo cancer imaging. ChemMedChem. 2014 Jun; 9(6):1131-5.
    View in: PubMed
  30. Hilgendorf I, Theurl I, Gerhardt LM, Robbins CS, Weber GF, Gonen A, Iwamoto Y, Degousee N, Holderried TA, Winter C, Zirlik A, Lin HY, Sukhova GK, Butany J, Rubin BB, Witztum JL, Libby P, Nahrendorf M, Weissleder R, Swirski FK. Innate response activator B cells aggravate atherosclerosis by stimulating T helper-1 adaptive immunity. Circulation. 2014 Apr 22; 129(16):1677-87.
    View in: PubMed
  31. Weissleder R, Nahrendorf M, Pittet MJ. Imaging macrophages with nanoparticles. Nat Mater. 2014 Jan 23; 13(2):125-38.
    View in: PubMed
  32. Ullal AV, Peterson V, Agasti SS, Tuang S, Juric D, Castro CM, Weissleder R. Cancer cell profiling by barcoding allows multiplexed protein analysis in fine-needle aspirates. Sci Transl Med. 2014 Jan 15; 6(219):219ra9.
    View in: PubMed
  33. Clardy SM, Keliher EJ, Mohan JF, Sebas M, Benoist C, Mathis D, Weissleder R. Fluorescent Exendin-4 Derivatives for Pancreatic ß-Cell Analysis. Bioconjug Chem. 2014 Jan 15; 25(1):171-7.
    View in: PubMed
  34. Courties G, Heidt T, Sebas M, Iwamoto Y, Jeon D, Truelove J, Tricot B, Wojtkiewicz G, Dutta P, Sager HB, Borodovsky A, Novobrantseva T, Klebanov B, Fitzgerald K, Anderson DG, Libby P, Swirski FK, Weissleder R, Nahrendorf M. In Vivo Silencing of the Transcription Factor IRF5 Reprograms the Macrophage Phenotype and Improves Infarct Healing. J Am Coll Cardiol. 2014 Apr 22; 63(15):1556-66.
    View in: PubMed
  35. Bronisz A, Wang Y, Nowicki MO, Peruzzi P, Ansari KI, Ogawa D, Balaj L, De Rienzo G, Mineo M, Nakano I, Ostrowski MC, Hochberg F, Weissleder R, Lawler SE, Chiocca EA, Godlewski J. Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1. Cancer Res. 2014 Feb 1; 74(3):738-50.
    View in: PubMed
  36. Rho J, Chung J, Im H, Liong M, Shao H, Castro CM, Weissleder R, Lee H. Magnetic nanosensor for detection and profiling of erythrocyte-derived microvesicles. ACS Nano. 2013 Dec 23; 7(12):11227-33.
    View in: PubMed
  37. Peterson VM, Castro CM, Chung J, Miller NC, Ullal AV, Castano MD, Penson RT, Lee H, Birrer MJ, Weissleder R. Ascites analysis by a microfluidic chip allows tumor-cell profiling. Proc Natl Acad Sci U S A. 2013 Dec 17; 110(51):E4978-86.
    View in: PubMed
  38. McDermott S, Thayer SP, Fernandez-Del Castillo C, Mino-Kenudson M, Weissleder R, Harisinghani MG. Accurate prediction of nodal status in preoperative patients with pancreatic ductal adenocarcinoma using next-gen nanoparticle. Transl Oncol. 2013 Dec 1; 6(6):670-5.
    View in: PubMed
  39. Kim E, Yang KS, Weissleder R. Bioorthogonal Small Molecule Imaging Agents Allow Single-Cell Imaging of MET. PLoS One. 2013; 8(11):e81275.
    View in: PubMed
  40. Ghazani AA, Pectasides M, Sharma A, Castro CM, Mino-Kenudson M, Lee H, Shepard JA, Weissleder R. Molecular characterization of scant lung tumor cells using iron-oxide nanoparticles and micro-nuclear magnetic resonance. Nanomedicine. 2014 Apr; 10(3):661-8.
    View in: PubMed
  41. Agasti SS, Laughney AM, Kohler RH, Weissleder R. A photoactivatable drug-caged fluorophore conjugate allows direct quantification of intracellular drug transport. Chem Commun (Camb). 2013 Oct 31; 49(94):11050-2.
    View in: PubMed
  42. Tassa C, Liong M, Hilderbrand S, Sandler JE, Reiner T, Keliher EJ, Weissleder R, Shaw SY. Microfluidic on-chip capture-cycloaddition reaction to reversibly immobilize small molecules or multi-component structures for biosensor applications. J Vis Exp. 2013; (79):e50772.
    View in: PubMed
  43. Chung J, Issadore D, Ullal A, Lee K, Weissleder R, Lee H. Rare cell isolation and profiling on a hybrid magnetic/size-sorting chip. Biomicrofluidics. 2013; 7(5):54107.
    View in: PubMed
  44. Vinegoni C, Lee S, Feruglio PF, Marzola P, Nahrendorf M, Weissleder R. Sequential average segmented microscopy for high signal-to-noise ratio motion-artifact-free in vivo heart imaging. Biomed Opt Express. 2013; 4(10):2095-106.
    View in: PubMed
  45. Yang KS, Budin G, Tassa C, Kister O, Weissleder R. Bioorthogonal approach to identify unsuspected drug targets in live cells. Angew Chem Int Ed Engl. 2013 Sep 27; 52(40):10593-7.
    View in: PubMed
  46. Robbins CS, Hilgendorf I, Weber GF, Theurl I, Iwamoto Y, Figueiredo JL, Gorbatov R, Sukhova GK, Gerhardt LM, Smyth D, Zavitz CC, Shikatani EA, Parsons M, van Rooijen N, Lin HY, Husain M, Libby P, Nahrendorf M, Weissleder R, Swirski FK. Local proliferation dominates lesional macrophage accumulation in atherosclerosis. Nat Med. 2013 Sep; 19(9):1166-72.
    View in: PubMed
  47. Castro CM, Ghazani AA, Chung J, Shao H, Issadore D, Yoon TJ, Weissleder R, Lee H. Miniaturized nuclear magnetic resonance platform for detection and profiling of circulating tumor cells. Lab Chip. 2014 Jan 7; 14(1):14-23.
    View in: PubMed
  48. Keliher EJ, Reiner T, Earley S, Klubnick J, Tassa C, Lee AJ, Ramaswamy S, Bardeesy N, Hanahan D, Depinho RA, Castro CM, Weissleder R. Targeting cathepsin E in pancreatic cancer by a small molecule allows in vivo detection. Neoplasia. 2013 Jul; 15(7):684-93.
    View in: PubMed
  49. Ueno T, Dutta P, Keliher E, Leuschner F, Majmudar M, Marinelli B, Iwamoto Y, Figueiredo JL, Christen T, Swirski FK, Libby P, Weissleder R, Nahrendorf M. Nanoparticle PET-CT detects rejection and immunomodulation in cardiac allografts. Circ Cardiovasc Imaging. 2013 Jul; 6(4):568-73.
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  50. Gounaris E, Martin J, Ishihara Y, Khan MW, Lee G, Sinh P, Chen EZ, Angarone M, Weissleder R, Khazaie K, Barrett TA. Fluorescence endoscopy of cathepsin activity discriminates dysplasia from colitis. Inflamm Bowel Dis. 2013 Jun; 19(7):1339-45.
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  51. Carlson JC, Meimetis LG, Hilderbrand SA, Weissleder R. BODIPY-tetrazine derivatives as superbright bioorthogonal turn-on probes. Angew Chem Int Ed Engl. 2013 Jul 1; 52(27):6917-20.
    View in: PubMed
  52. Zeglis BM, Sevak KK, Reiner T, Mohindra P, Carlin SD, Zanzonico P, Weissleder R, Lewis JS. A pretargeted PET imaging strategy based on bioorthogonal Diels-Alder click chemistry. J Nucl Med. 2013 Aug; 54(8):1389-96.
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  53. Chung HJ, Castro CM, Im H, Lee H, Weissleder R. A magneto-DNA nanoparticle system for rapid detection and phenotyping of bacteria. Nat Nanotechnol. 2013 May; 8(5):369-75.
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  54. Majmudar MD, Keliher EJ, Heidt T, Leuschner F, Truelove J, Sena BF, Gorbatov R, Iwamoto Y, Dutta P, Wojtkiewicz G, Courties G, Sebas M, Borodovsky A, Fitzgerald K, Nolte MW, Dickneite G, Chen JW, Anderson DG, Swirski FK, Weissleder R, Nahrendorf M. Monocyte-directed RNAi targeting CCR2 improves infarct healing in atherosclerosis-prone mice. Circulation. 2013 May 21; 127(20):2038-46.
    View in: PubMed
  55. Giedt RJ, Koch PD, Weissleder R. Single cell analysis of drug distribution by intravital imaging. PLoS One. 2013; 8(4):e60988.
    View in: PubMed
  56. Ghazani AA, McDermott S, Pectasides M, Sebas M, Mino-Kenudson M, Lee H, Weissleder R, Castro CM. Comparison of select cancer biomarkers in human circulating and bulk tumor cells using magnetic nanoparticles and a miniaturized micro-NMR system. Nanomedicine. 2013 Oct; 9(7):1009-17.
    View in: PubMed
  57. Shan G, Weissleder R, Hilderbrand SA. Upconverting organic dye doped core-shell nano-composites for dual-modality NIR imaging and photo-thermal therapy. Theranostics. 2013; 3(4):267-74.
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  58. Issadore D, Chung HJ, Chung J, Budin G, Weissleder R, Lee H. µHall chip for sensitive detection of bacteria. Adv Healthc Mater. 2013 Sep; 2(9):1224-8.
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  59. Liu R, Rallo R, Weissleder R, Tassa C, Shaw S, Cohen Y. Nano-SAR development for bioactivity of nanoparticles with considerations of decision boundaries. Small. 2013 May 27; 9(9-10):1842-52.
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  60. Cortez-Retamozo V, Etzrodt M, Newton A, Ryan R, Pucci F, Sio SW, Kuswanto W, Rauch PJ, Chudnovskiy A, Iwamoto Y, Kohler R, Marinelli B, Gorbatov R, Wojtkiewicz G, Panizzi P, Mino-Kenudson M, Forghani R, Figueiredo JL, Chen JW, Xavier R, Swirski FK, Nahrendorf M, Weissleder R, Pittet MJ. Angiotensin II drives the production of tumor-promoting macrophages. Immunity. 2013 Feb 21; 38(2):296-308.
    View in: PubMed
  61. Majmudar MD, Yoo J, Keliher EJ, Truelove JJ, Iwamoto Y, Sena B, Dutta P, Borodovsky A, Fitzgerald K, Di Carli MF, Libby P, Anderson DG, Swirski FK, Weissleder R, Nahrendorf M. Polymeric nanoparticle PET/MR imaging allows macrophage detection in atherosclerotic plaques. Circ Res. 2013 Mar 1; 112(5):755-61.
    View in: PubMed
  62. Thurber GM, Yang KS, Reiner T, Kohler RH, Sorger P, Mitchison T, Weissleder R. Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo. Nat Commun. 2013; 4:1504.
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  63. Liong M, Hoang AN, Chung J, Gural N, Ford CB, Min C, Shah RR, Ahmad R, Fernandez-Suarez M, Fortune SM, Toner M, Lee H, Weissleder R. Magnetic barcode assay for genetic detection of pathogens. Nat Commun. 2013; 4:1752.
    View in: PubMed
  64. Kastrup CJ, Nahrendorf M, Figueiredo JL, Lee H, Kambhampati S, Lee T, Cho SW, Gorbatov R, Iwamoto Y, Dang TT, Dutta P, Yeon JH, Cheng H, Pritchard CD, Vegas AJ, Siegel CD, MacDougall S, Okonkwo M, Thai A, Stone JR, Coury AJ, Weissleder R, Langer R, Anderson DG. Painting blood vessels and atherosclerotic plaques with an adhesive drug depot. Proc Natl Acad Sci U S A. 2012 Dec 26; 109(52):21444-9.
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  65. Sebastián C, Zwaans BM, Silberman DM, Gymrek M, Goren A, Zhong L, Ram O, Truelove J, Guimaraes AR, Toiber D, Cosentino C, Greenson JK, MacDonald AI, McGlynn L, Maxwell F, Edwards J, Giacosa S, Guccione E, Weissleder R, Bernstein BE, Regev A, Shiels PG, Lombard DB, Mostoslavsky R. The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism. Cell. 2012 Dec 7; 151(6):1185-99.
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  66. Lee J, Li M, Milwid J, Dunham J, Vinegoni C, Gorbatov R, Iwamoto Y, Wang F, Shen K, Hatfield K, Enger M, Shafiee S, McCormack E, Ebert BL, Weissleder R, Yarmush ML, Parekkadan B. Implantable microenvironments to attract hematopoietic stem/cancer cells. Proc Natl Acad Sci U S A. 2012 Nov 27; 109(48):19638-43.
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  67. Shao H, Chung J, Balaj L, Charest A, Bigner DD, Carter BS, Hochberg FH, Breakefield XO, Weissleder R, Lee H. Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy. Nat Med. 2012 Dec; 18(12):1835-40.
    View in: PubMed
  68. Agasti SS, Liong M, Peterson VM, Lee H, Weissleder R. Photocleavable DNA barcode-antibody conjugates allow sensitive and multiplexed protein analysis in single cells. J Am Chem Soc. 2012 Nov 14; 134(45):18499-502.
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  69. Chen JW, Figueiredo JL, Wojtkiewicz GR, Siegel C, Iwamoto Y, Kim DE, Nolte MW, Dickneite G, Weissleder R, Nahrendorf M. Selective factor XIIa inhibition attenuates silent brain ischemia: application of molecular imaging targeting coagulation pathway. JACC Cardiovasc Imaging. 2012 Nov; 5(11):1127-38.
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  70. Epa VC, Burden FR, Tassa C, Weissleder R, Shaw S, Winkler DA. Modeling biological activities of nanoparticles. Nano Lett. 2012 Nov 14; 12(11):5808-12.
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  71. Agasti SS, Kohler RH, Liong M, Peterson VM, Lee H, Weissleder R. Dual imaging and photoactivated nanoprobe for controlled cell tracking. Small. 2013 Jan 28; 9(2):222-7.
    View in: PubMed
  72. Ripplinger CM, Kessinger CW, Li C, Kim JW, McCarthy JR, Weissleder R, Henke PK, Lin CP, Jaffer FA. Inflammation modulates murine venous thrombosis resolution in vivo: assessment by multimodal fluorescence molecular imaging. Arterioscler Thromb Vasc Biol. 2012 Nov; 32(11):2616-24.
    View in: PubMed
  73. Lee S, Vinegoni C, Feruglio PF, Weissleder R. Improved intravital microscopy via synchronization of respiration and holder stabilization. J Biomed Opt. 2012 Sep; 17(9):96018-1.
    View in: PubMed
  74. Lu X, Agasti SS, Vinegoni C, Waterman P, DePinho RA, Weissleder R. Optochemogenetics (OCG) allows more precise control of genetic engineering in mice with CreER regulators. Bioconjug Chem. 2012 Sep 19; 23(9):1945-51.
    View in: PubMed
  75. Waters JD, Sanchez C, Sahin A, Futalan D, Gonda DD, Scheer JK, Akers J, Palanichamy K, Waterman P, Chakravarti A, Weissleder R, Morse B, Marsh N, Furfine E, Chen CC, Carvajal I, Carter BS. CT322, a VEGFR-2 antagonist, demonstrates anti-glioma efficacy in orthotopic brain tumor model as a single agent or in combination with temozolomide and radiation therapy. J Neurooncol. 2012 Oct; 110(1):37-48.
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  76. Feruglio PF, Vinegoni C, Fexon L, Thurber G, Sbarbati A, Weissleder R. Noise suppressed, multifocus image fusion for enhanced intraoperative navigation. J Biophotonics. 2013 Apr; 6(4):363-70.
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  77. Dutta P, Courties G, Wei Y, Leuschner F, Gorbatov R, Robbins CS, Iwamoto Y, Thompson B, Carlson AL, Heidt T, Majmudar MD, Lasitschka F, Etzrodt M, Waterman P, Waring MT, Chicoine AT, van der Laan AM, Niessen HW, Piek JJ, Rubin BB, Butany J, Stone JR, Katus HA, Murphy SA, Morrow DA, Sabatine MS, Vinegoni C, Moskowitz MA, Pittet MJ, Libby P, Lin CP, Swirski FK, Weissleder R, Nahrendorf M. Myocardial infarction accelerates atherosclerosis. Nature. 2012 Jul 19; 487(7407):325-9.
    View in: PubMed
  78. Min C, Shao H, Liong M, Yoon TJ, Weissleder R, Lee H. Mechanism of magnetic relaxation switching sensing. ACS Nano. 2012 Aug 28; 6(8):6821-8.
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  79. Issadore D, Chung J, Shao H, Liong M, Ghazani AA, Castro CM, Weissleder R, Lee H. Ultrasensitive clinical enumeration of rare cells ex vivo using a micro-hall detector. Sci Transl Med. 2012 Jul 4; 4(141):141ra92.
    View in: PubMed
  80. Tassa C, Liong M, Hilderbrand S, Sandler JE, Reiner T, Keliher EJ, Weissleder R, Shaw SY. On-chip bioorthogonal chemistry enables immobilization of in situ modified nanoparticles and small molecules for label-free monitoring of protein binding and reaction kinetics. Lab Chip. 2012 Sep 7; 12(17):3103-10.
    View in: PubMed
  81. Budin G, Chung HJ, Lee H, Weissleder R. A magnetic Gram stain for bacterial detection. Angew Chem Int Ed Engl. 2012 Jul 27; 51(31):7752-5.
    View in: PubMed
  82. Fukuda D, Aikawa E, Swirski FK, Novobrantseva TI, Kotelianski V, Gorgun CZ, Chudnovskiy A, Yamazaki H, Croce K, Weissleder R, Aster JC, Hotamisligil GS, Yagita H, Aikawa M. Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders. Proc Natl Acad Sci U S A. 2012 Jul 3; 109(27):E1868-77.
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  83. Hara T, Bhayana B, Thompson B, Kessinger CW, Khatri A, McCarthy JR, Weissleder R, Lin CP, Tearney GJ, Jaffer FA. Molecular imaging of fibrin deposition in deep vein thrombosis using fibrin-targeted near-infrared fluorescence. JACC Cardiovasc Imaging. 2012 Jun; 5(6):607-15.
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  84. Yang KS, Budin G, Reiner T, Vinegoni C, Weissleder R. Bioorthogonal imaging of aurora kinase A in live cells. Angew Chem Int Ed Engl. 2012 Jul 2; 51(27):6598-603.
    View in: PubMed
  85. Chung J, Shao H, Reiner T, Issadore D, Weissleder R, Lee H. Microfluidic cell sorter (µFCS) for on-chip capture and analysis of single cells. Adv Healthc Mater. 2012 Jul; 1(4):432-6.
    View in: PubMed
  86. Ghazani AA, Castro CM, Gorbatov R, Lee H, Weissleder R. Sensitive and direct detection of circulating tumor cells by multimarker µ-nuclear magnetic resonance. Neoplasia. 2012 May; 14(5):388-95.
    View in: PubMed
  87. Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, Locasale JW, Son J, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, Paik JH, Lim C, Guimaraes AR, Martin ES, Chang J, Hezel AF, Perry SR, Hu J, Gan B, Xiao Y, Asara JM, Weissleder R, Wang YA, Chin L, Cantley LC, DePinho RA. Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cell. 2012 Apr 27; 149(3):656-70.
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  88. Etzrodt M, Cortez-Retamozo V, Newton A, Zhao J, Ng A, Wildgruber M, Romero P, Wurdinger T, Xavier R, Geissmann F, Meylan E, Nahrendorf M, Swirski FK, Baltimore D, Weissleder R, Pittet MJ. Regulation of monocyte functional heterogeneity by miR-146a and Relb. Cell Rep. 2012 Apr 19; 1(4):317-24.
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  89. Earley S, Vinegoni C, Dunham J, Gorbatov R, Feruglio PF, Weissleder R. In vivo imaging of drug-induced mitochondrial outer membrane permeabilization at single-cell resolution. Cancer Res. 2012 Jun 15; 72(12):2949-56.
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  90. Liu X, Nielsen GP, Rosenberg AE, Waterman PR, Yang W, Choy E, Sassi S, Yang S, Harmon DC, Yang C, Schwab JH, Kobayashi E, Mankin HJ, Xavier R, Weissleder R, Duan Z, Hornicek FJ. Establishment and characterization of a novel chordoma cell line: CH22. J Orthop Res. 2012 Oct; 30(10):1666-73.
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  91. Vinegoni C, Fumene Feruglio P, Razansky D, Gorbatov R, Ntziachristos V, Sbarbati A, Nahrendorf M, Weissleder R. Mapping molecular agents distributions in whole mice hearts using born-normalized optical projection tomography. PLoS One. 2012; 7(4):e34427.
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  92. Hendricks JA, Keliher EJ, Wan D, Hilderbrand SA, Weissleder R, Mazitschek R. Synthesis of [18F]BODIPY: bifunctional reporter for hybrid optical/positron emission tomography imaging. Angew Chem Int Ed Engl. 2012 May 7; 51(19):4603-6.
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  93. Peterson VM, Castro CM, Lee H, Weissleder R. Orthogonal amplification of nanoparticles for improved diagnostic sensing. ACS Nano. 2012 Apr 24; 6(4):3506-13.
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  94. Forghani R, Wojtkiewicz GR, Zhang Y, Seeburg D, Bautz BR, Pulli B, Milewski AR, Atkinson WL, Iwamoto Y, Zhang ER, Etzrodt M, Rodriguez E, Robbins CS, Swirski FK, Weissleder R, Chen JW. Demyelinating diseases: myeloperoxidase as an imaging biomarker and therapeutic target. Radiology. 2012 May; 263(2):451-60.
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  95. Devaraj NK, Thurber GM, Keliher EJ, Marinelli B, Weissleder R. Reactive polymer enables efficient in vivo bioorthogonal chemistry. Proc Natl Acad Sci U S A. 2012 Mar 27; 109(13):4762-7.
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  96. Niers JM, Chen JW, Lewandrowski G, Kerami M, Garanger E, Wojtkiewicz G, Waterman P, Keliher E, Weissleder R, Tannous BA. Single reporter for targeted multimodal in vivo imaging. J Am Chem Soc. 2012 Mar 21; 134(11):5149-56.
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  97. Reiner T, Lacy J, Keliher EJ, Yang KS, Ullal A, Kohler RH, Vinegoni C, Weissleder R. Imaging therapeutic PARP inhibition in vivo through bioorthogonally developed companion imaging agents. Neoplasia. 2012 Mar; 14(3):169-77.
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  98. Fu W, Wojtkiewicz G, Weissleder R, Benoist C, Mathis D. Early window of diabetes determinism in NOD mice, dependent on the complement receptor CRIg, identified by noninvasive imaging. Nat Immunol. 2012 Apr; 13(4):361-8.
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  99. McCarthy JR, Sazonova IY, Erdem SS, Hara T, Thompson BD, Patel P, Botnaru I, Lin CP, Reed GL, Weissleder R, Jaffer FA. Multifunctional nanoagent for thrombus-targeted fibrinolytic therapy. Nanomedicine (Lond). 2012 Jul; 7(7):1017-28.
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  100. Rao SM, Auger JL, Gaillard P, Weissleder R, Wada E, Torres R, Kojima M, Benoist C, Mathis D, Binstadt BA. The neuropeptide neuromedin U promotes autoantibody-mediated arthritis. Arthritis Res Ther. 2012; 14(1):R29.
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  101. Cortez-Retamozo V, Etzrodt M, Newton A, Rauch PJ, Chudnovskiy A, Berger C, Ryan RJ, Iwamoto Y, Marinelli B, Gorbatov R, Forghani R, Novobrantseva TI, Koteliansky V, Figueiredo JL, Chen JW, Anderson DG, Nahrendorf M, Swirski FK, Weissleder R, Pittet MJ. Origins of tumor-associated macrophages and neutrophils. Proc Natl Acad Sci U S A. 2012 Feb 14; 109(7):2491-6.
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  102. Novobrantseva TI, Borodovsky A, Wong J, Klebanov B, Zafari M, Yucius K, Querbes W, Ge P, Ruda VM, Milstein S, Speciner L, Duncan R, Barros S, Basha G, Cullis P, Akinc A, Donahoe JS, Narayanannair Jayaprakash K, Jayaraman M, Bogorad RL, Love K, Whitehead K, Levins C, Manoharan M, Swirski FK, Weissleder R, Langer R, Anderson DG, de Fougerolles A, Nahrendorf M, Koteliansky V. Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells. Mol Ther Nucleic Acids. 2012; 1:e4.
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  103. Rauch PJ, Chudnovskiy A, Robbins CS, Weber GF, Etzrodt M, Hilgendorf I, Tiglao E, Figueiredo JL, Iwamoto Y, Theurl I, Gorbatov R, Waring MT, Chicoine AT, Mouded M, Pittet MJ, Nahrendorf M, Weissleder R, Swirski FK. Innate response activator B cells protect against microbial sepsis. Science. 2012 Feb 3; 335(6068):597-601.
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  104. Lee WW, Marinelli B, van der Laan AM, Sena BF, Gorbatov R, Leuschner F, Dutta P, Iwamoto Y, Ueno T, Begieneman MP, Niessen HW, Piek JJ, Vinegoni C, Pittet MJ, Swirski FK, Tawakol A, Di Carli M, Weissleder R, Nahrendorf M. PET/MRI of inflammation in myocardial infarction. J Am Coll Cardiol. 2012 Jan 10; 59(2):153-63.
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  105. Leuschner F, Rauch PJ, Ueno T, Gorbatov R, Marinelli B, Lee WW, Dutta P, Wei Y, Robbins C, Iwamoto Y, Sena B, Chudnovskiy A, Panizzi P, Keliher E, Higgins JM, Libby P, Moskowitz MA, Pittet MJ, Swirski FK, Weissleder R, Nahrendorf M. Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis. J Exp Med. 2012 Jan 16; 209(1):123-37.
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  106. Shao H, Min C, Issadore D, Liong M, Yoon TJ, Weissleder R, Lee H. Magnetic Nanoparticles and microNMR for Diagnostic Applications. Theranostics. 2012; 2(1):55-65.
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  107. Lee S, Vinegoni C, Feruglio PF, Fexon L, Gorbatov R, Pivoravov M, Sbarbati A, Nahrendorf M, Weissleder R. Real-time in vivo imaging of the beating mouse heart at microscopic resolution. Nat Commun. 2012; 3:1054.
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  108. Karver MR, Weissleder R, Hilderbrand SA. Bioorthogonal reaction pairs enable simultaneous, selective, multi-target imaging. Angew Chem Int Ed Engl. 2012 Jan 23; 51(4):920-2.
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  109. Robbins CS, Chudnovskiy A, Rauch PJ, Figueiredo JL, Iwamoto Y, Gorbatov R, Etzrodt M, Weber GF, Ueno T, van Rooijen N, Mulligan-Kehoe MJ, Libby P, Nahrendorf M, Pittet MJ, Weissleder R, Swirski FK. Extramedullary hematopoiesis generates Ly-6C(high) monocytes that infiltrate atherosclerotic lesions. Circulation. 2012 Jan 17; 125(2):364-74.
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  110. Agasti SS, Liong M, Tassa C, Chung HJ, Shaw SY, Lee H, Weissleder R. Supramolecular host-guest interaction for labeling and detection of cellular biomarkers. Angew Chem Int Ed Engl. 2012 Jan 9; 51(2):450-4.
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  111. Pittet MJ, Weissleder R. Intravital imaging. Cell. 2011 Nov 23; 147(5):983-91.
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  112. Su HS, Nahrendorf M, Panizzi P, Breckwoldt MO, Rodriguez E, Iwamoto Y, Aikawa E, Weissleder R, Chen JW. Vasculitis: molecular imaging by targeting the inflammatory enzyme myeloperoxidase. Radiology. 2012 Jan; 262(1):181-90.
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  113. Keliher EJ, Yoo J, Nahrendorf M, Lewis JS, Marinelli B, Newton A, Pittet MJ, Weissleder R. 89Zr-labeled dextran nanoparticles allow in vivo macrophage imaging. Bioconjug Chem. 2011 Dec 21; 22(12):2383-9.
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  114. Liong M, Fernandez-Suarez M, Issadore D, Min C, Tassa C, Reiner T, Fortune SM, Toner M, Lee H, Weissleder R. Specific pathogen detection using bioorthogonal chemistry and diagnostic magnetic resonance. Bioconjug Chem. 2011 Dec 21; 22(12):2390-4.
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  115. Weissleder R, Castro C. Interview: Nanomedicine in oncology: miniaturized means to an enormous end. Interviewed by Cara Sutton. Nanomedicine (Lond). 2011 Nov; 6(9):1495-8.
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  116. Karver MR, Weissleder R, Hilderbrand SA. Synthesis and evaluation of a series of 1,2,4,5-tetrazines for bioorthogonal conjugation. Bioconjug Chem. 2011 Nov 16; 22(11):2263-70.
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  117. Ullal AV, Reiner T, Yang KS, Gorbatov R, Min C, Issadore D, Lee H, Weissleder R. Nanoparticle-mediated measurement of target-drug binding in cancer cells. ACS Nano. 2011 Nov 22; 5(11):9216-24.
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  118. Chung HJ, Reiner T, Budin G, Min C, Liong M, Issadore D, Lee H, Weissleder R. Ubiquitous detection of gram-positive bacteria with bioorthogonal magnetofluorescent nanoparticles. ACS Nano. 2011 Nov 22; 5(11):8834-41.
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  119. Leuschner F, Dutta P, Gorbatov R, Novobrantseva TI, Donahoe JS, Courties G, Lee KM, Kim JI, Markmann JF, Marinelli B, Panizzi P, Lee WW, Iwamoto Y, Milstein S, Epstein-Barash H, Cantley W, Wong J, Cortez-Retamozo V, Newton A, Love K, Libby P, Pittet MJ, Swirski FK, Koteliansky V, Langer R, Weissleder R, Anderson DG, Nahrendorf M. Therapeutic siRNA silencing in inflammatory monocytes in mice. Nat Biotechnol. 2011 Nov; 29(11):1005-10.
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  120. Settles M, Etzrodt M, Kosanke K, Schiemann M, Zimmermann A, Meier R, Braren R, Huber A, Rummeny EJ, Weissleder R, Swirski FK, Wildgruber M. Different capacity of monocyte subsets to phagocytose iron-oxide nanoparticles. PLoS One. 2011; 6(10):e25197.
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  121. Yoon TJ, Lee H, Shao H, Hilderbrand SA, Weissleder R. Multicore assemblies potentiate magnetic properties of biomagnetic nanoparticles. Adv Mater. 2011 Nov 2; 23(41):4793-7.
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  122. Zeglis BM, Mohindra P, Weissmann GI, Divilov V, Hilderbrand SA, Weissleder R, Lewis JS. Modular strategy for the construction of radiometalated antibodies for positron emission tomography based on inverse electron demand Diels-Alder click chemistry. Bioconjug Chem. 2011 Oct 19; 22(10):2048-59.
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  123. Thurber GM, Weissleder R. A systems approach for tumor pharmacokinetics. PLoS One. 2011; 6(9):e24696.
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  124. Zhang W, Fulci G, Buhrman JS, Stemmer-Rachamimov AO, Chen JW, Wojtkiewicz GR, Weissleder R, Rabkin SD, Martuza RL. Bevacizumab with angiostatin-armed oHSV increases antiangiogenesis and decreases bevacizumab-induced invasion in U87 glioma. Mol Ther. 2012 Jan; 20(1):37-45.
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  125. Budin G, Yang KS, Reiner T, Weissleder R. Bioorthogonal probes for polo-like kinase 1 imaging and quantification. Angew Chem Int Ed Engl. 2011 Sep 26; 50(40):9378-81.
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  126. Panizzi P, Nahrendorf M, Figueiredo JL, Panizzi J, Marinelli B, Iwamoto Y, Keliher E, Maddur AA, Waterman P, Kroh HK, Leuschner F, Aikawa E, Swirski FK, Pittet MJ, Hackeng TM, Fuentes-Prior P, Schneewind O, Bock PE, Weissleder R. In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation. Nat Med. 2011 Sep; 17(9):1142-6.
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  127. Thurber GM, Weissleder R. Quantitating antibody uptake in vivo: conditional dependence on antigen expression levels. Mol Imaging Biol. 2011 Aug; 13(4):623-32.
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  128. Liong M, Tassa C, Shaw SY, Lee H, Weissleder R. Multiplexed magnetic labeling amplification using oligonucleotide hybridization. Adv Mater. 2011 Sep 22; 23(36):H254-7.
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  129. Hendricks JA, Keliher EJ, Marinelli B, Reiner T, Weissleder R, Mazitschek R. In vivo PET imaging of histone deacetylases by 18F-suberoylanilide hydroxamic acid (18F-SAHA). J Med Chem. 2011 Aug 11; 54(15):5576-82.
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  130. Reiner T, Thurber G, Gaglia J, Vinegoni C, Liew CW, Upadhyay R, Kohler RH, Li L, Kulkarni RN, Benoist C, Mathis D, Weissleder R. Accurate measurement of pancreatic islet beta-cell mass using a second-generation fluorescent exendin-4 analog. Proc Natl Acad Sci U S A. 2011 Aug 2; 108(31):12815-20.
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  131. Orth JD, Kohler RH, Foijer F, Sorger PK, Weissleder R, Mitchison TJ. Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics. Cancer Res. 2011 Jul 1; 71(13):4608-16.
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  132. Jaffer FA, Calfon MA, Rosenthal A, Mallas G, Razansky RN, Mauskapf A, Weissleder R, Libby P, Ntziachristos V. Two-dimensional intravascular near-infrared fluorescence molecular imaging of inflammation in atherosclerosis and stent-induced vascular injury. J Am Coll Cardiol. 2011 Jun 21; 57(25):2516-26.
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  133. Tassa C, Shaw SY, Weissleder R. Dextran-coated iron oxide nanoparticles: a versatile platform for targeted molecular imaging, molecular diagnostics, and therapy. Acc Chem Res. 2011 Oct 18; 44(10):842-52.
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  134. Devaraj NK, Weissleder R. Biomedical applications of tetrazine cycloadditions. Acc Chem Res. 2011 Sep 20; 44(9):816-27.
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  135. Vinegoni C, Botnaru I, Aikawa E, Calfon MA, Iwamoto Y, Folco EJ, Ntziachristos V, Weissleder R, Libby P, Jaffer FA. Indocyanine green enables near-infrared fluorescence imaging of lipid-rich, inflamed atherosclerotic plaques. Sci Transl Med. 2011 May 25; 3(84):84ra45.
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  136. Buxton DB, Antman M, Danthi N, Dilsizian V, Fayad ZA, Garcia MJ, Jaff MR, Klimas M, Libby P, Nahrendorf M, Sinusas AJ, Wickline SA, Wu JC, Bonow RO, Weissleder R. Report of the National Heart, Lung, and Blood Institute working group on the translation of cardiovascular molecular imaging. Circulation. 2011 May 17; 123(19):2157-63.
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  137. Kleijn A, Chen JW, Buhrman JS, Wojtkiewicz GR, Iwamoto Y, Lamfers ML, Stemmer-Rachamimov AO, Rabkin SD, Weissleder R, Martuza RL, Fulci G. Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging. Clin Cancer Res. 2011 Jul 1; 17(13):4484-93.
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  138. Issadore D, Min C, Liong M, Chung J, Weissleder R, Lee H. Miniature magnetic resonance system for point-of-care diagnostics. Lab Chip. 2011 Jul 7; 11(13):2282-7.
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  139. Yoon TJ, Lee H, Shao H, Weissleder R. Highly magnetic core-shell nanoparticles with a unique magnetization mechanism. Angew Chem Int Ed Engl. 2011 May 9; 50(20):4663-6.
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  140. Guimaraes AR, Ross R, Figuereido JL, Waterman P, Weissleder R. MRI with magnetic nanoparticles monitors downstream anti-angiogenic effects of mTOR inhibition. Mol Imaging Biol. 2011 Apr; 13(2):314-20.
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  141. Deliolanis NC, Wurdinger T, Pike L, Tannous BA, Breakefield XO, Weissleder R, Ntziachristos V. In vivo tomographic imaging of red-shifted fluorescent proteins. Biomed Opt Express. 2011; 2(4):887-900.
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  142. Haun JB, Devaraj NK, Marinelli BS, Lee H, Weissleder R. Probing intracellular biomarkers and mediators of cell activation using nanosensors and bioorthogonal chemistry. ACS Nano. 2011 Apr 26; 5(4):3204-13.
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  143. Figueiredo JL, Nahrendorf M, Vinegoni C, Weissleder R. Intraoperative near-infrared fluorescent cholangiography (NIRFC) in mouse models of bile duct injury: reply. World J Surg. 2011 Mar; 35(3):694-5.
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  144. Haun JB, Castro CM, Wang R, Peterson VM, Marinelli BS, Lee H, Weissleder R. Micro-NMR for rapid molecular analysis of human tumor samples. Sci Transl Med. 2011 Feb 23; 3(71):71ra16.
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  145. Reiner T, Keliher EJ, Earley S, Marinelli B, Weissleder R. Synthesis and in vivo imaging of a 18F-labeled PARP1 inhibitor using a chemically orthogonal scavenger-assisted high-performance method. Angew Chem Int Ed Engl. 2011 Feb 18; 50(8):1922-5.
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  146. Nahrendorf M, Keliher E, Marinelli B, Leuschner F, Robbins CS, Gerszten RE, Pittet MJ, Swirski FK, Weissleder R. Detection of macrophages in aortic aneurysms by nanoparticle positron emission tomography-computed tomography. Arterioscler Thromb Vasc Biol. 2011 Apr; 31(4):750-7.
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  147. Quillard T, Croce K, Jaffer FA, Weissleder R, Libby P. Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo. Thromb Haemost. 2011 May; 105(5):828-36.
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  148. Niers JM, Chen JW, Weissleder R, Tannous BA. Enhanced in vivo imaging of metabolically biotinylated cell surface reporters. Anal Chem. 2011 Feb 1; 83(3):994-9.
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  149. Keliher EJ, Reiner T, Turetsky A, Hilderbrand SA, Weissleder R. High-yielding, two-step 18F labeling strategy for 18F-PARP1 inhibitors. ChemMedChem. 2011 Mar 7; 6(3):424-7.
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  150. Haun JB, Yoon TJ, Lee H, Weissleder R. Molecular detection of biomarkers and cells using magnetic nanoparticles and diagnostic magnetic resonance. Methods Mol Biol. 2011; 726:33-49.
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  151. Xia Y, Cortez-Retamozo V, Niederkofler V, Salie R, Chen S, Samad TA, Hong CC, Arber S, Vyas JM, Weissleder R, Pittet MJ, Lin HY. Dragon (repulsive guidance molecule b) inhibits IL-6 expression in macrophages. J Immunol. 2011 Feb 1; 186(3):1369-76.
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  152. Shao H, Yoon TJ, Liong M, Weissleder R, Lee H. Magnetic nanoparticles for biomedical NMR-based diagnostics. Beilstein J Nanotechnol. 2010; 1:142-54.
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  153. Thurber GM, Figueiredo JL, Weissleder R. Detection limits of intraoperative near infrared imaging for tumor resection. J Surg Oncol. 2010 Dec 1; 102(7):758-64.
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  154. Liong M, Shao H, Haun JB, Lee H, Weissleder R. Carboxymethylated polyvinyl alcohol stabilizes doped ferrofluids for biological applications. Adv Mater. 2010 Dec 1; 22(45):5168-72.
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  155. Gaglia JL, Guimaraes AR, Harisinghani M, Turvey SE, Jackson R, Benoist C, Mathis D, Weissleder R. Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients. J Clin Invest. 2011 Jan; 121(1):442-5.
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  156. Reiner T, Earley S, Turetsky A, Weissleder R. Bioorthogonal small-molecule ligands for PARP1 imaging in living cells. Chembiochem. 2010 Nov 22; 11(17):2374-7.
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  157. Gros J, Hu JK, Vinegoni C, Feruglio PF, Weissleder R, Tabin CJ. WNT5A/JNK and FGF/MAPK pathways regulate the cellular events shaping the vertebrate limb bud. Curr Biol. 2010 Nov 23; 20(22):1993-2002.
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  158. Kraehenbuehl TP, Ferreira LS, Hayward AM, Nahrendorf M, van der Vlies AJ, Vasile E, Weissleder R, Langer R, Hubbell JA. Human embryonic stem cell-derived microvascular grafts for cardiac tissue preservation after myocardial infarction. Biomaterials. 2011 Feb; 32(4):1102-9.
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  159. Fourches D, Pu D, Tassa C, Weissleder R, Shaw SY, Mumper RJ, Tropsha A. Quantitative nanostructure-activity relationship modeling. ACS Nano. 2010 Oct 26; 4(10):5703-12.
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  160. Parekkadan B, Upadhyay R, Dunham J, Iwamoto Y, Mizoguchi E, Mizoguchi A, Weissleder R, Yarmush ML. Bone marrow stromal cell transplants prevent experimental enterocolitis and require host CD11b+ splenocytes. Gastroenterology. 2011 Mar; 140(3):966-75.
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  161. Issadore D, Shao H, Chung J, Newton A, Pittet M, Weissleder R, Lee H. Self-assembled magnetic filter for highly efficient immunomagnetic separation. Lab Chip. 2011 Jan 7; 11(1):147-51.
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  162. Morishige K, Kacher DF, Libby P, Josephson L, Ganz P, Weissleder R, Aikawa M. High-resolution magnetic resonance imaging enhanced with superparamagnetic nanoparticles measures macrophage burden in atherosclerosis. Circulation. 2010 Oct 26; 122(17):1707-15.
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  163. Leuschner F, Panizzi P, Chico-Calero I, Lee WW, Ueno T, Cortez-Retamozo V, Waterman P, Gorbatov R, Marinelli B, Iwamoto Y, Chudnovskiy A, Figueiredo JL, Sosnovik DE, Pittet MJ, Swirski FK, Weissleder R, Nahrendorf M. Angiotensin-converting enzyme inhibition prevents the release of monocytes from their splenic reservoir in mice with myocardial infarction. Circ Res. 2010 Nov 26; 107(11):1364-73.
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  164. Condeelis J, Weissleder R. In vivo imaging in cancer. Cold Spring Harb Perspect Biol. 2010 Dec; 2(12):a003848.
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  165. McCarthy JR, Korngold E, Weissleder R, Jaffer FA. A light-activated theranostic nanoagent for targeted macrophage ablation in inflammatory atherosclerosis. Small. 2010 Sep 20; 6(18):2041-9.
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  166. Kim K, Doi A, Wen B, Ng K, Zhao R, Cahan P, Kim J, Aryee MJ, Ji H, Ehrlich LI, Yabuuchi A, Takeuchi A, Cunniff KC, Hongguang H, McKinney-Freeman S, Naveiras O, Yoon TJ, Irizarry RA, Jung N, Seita J, Hanna J, Murakami P, Jaenisch R, Weissleder R, Orkin SH, Weissman IL, Feinberg AP, Daley GQ. Epigenetic memory in induced pluripotent stem cells. Nature. 2010 Sep 16; 467(7313):285-90.
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  167. McCarthy JR, Bhaumik J, Karver MR, Sibel Erdem S, Weissleder R. Targeted nanoagents for the detection of cancers. Mol Oncol. 2010 Dec; 4(6):511-28.
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  168. Fumene Feruglio P, Vinegoni C, Gros J, Sbarbati A, Weissleder R. Block matching 3D random noise filtering for absorption optical projection tomography. Phys Med Biol. 2010 Sep 21; 55(18):5401-15.
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  169. Chang K, Francis SA, Aikawa E, Figueiredo JL, Kohler RH, McCarthy JR, Weissleder R, Plutzky J, Jaffer FA. Pioglitazone suppresses inflammation in vivo in murine carotid atherosclerosis: novel detection by dual-target fluorescence molecular imaging. Arterioscler Thromb Vasc Biol. 2010 Oct; 30(10):1933-9.
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  170. Hjortnaes J, Gottlieb D, Figueiredo JL, Melero-Martin J, Kohler RH, Bischoff J, Weissleder R, Mayer JE, Aikawa E. Intravital molecular imaging of small-diameter tissue-engineered vascular grafts in mice: a feasibility study. Tissue Eng Part C Methods. 2010 Aug; 16(4):597-607.
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  171. Haun JB, Devaraj NK, Hilderbrand SA, Lee H, Weissleder R. Bioorthogonal chemistry amplifies nanoparticle binding and enhances the sensitivity of cell detection. Nat Nanotechnol. 2010 Sep; 5(9):660-5.
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  172. Reiner T, Kohler RH, Liew CW, Hill JA, Gaglia J, Kulkarni RN, Weissleder R. Near-infrared fluorescent probe for imaging of pancreatic beta cells. Bioconjug Chem. 2010 Jul 21; 21(7):1362-8.
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  173. Hjortnaes J, Butcher J, Figueiredo JL, Riccio M, Kohler RH, Kozloff KM, Weissleder R, Aikawa E. Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodelling: a role for inflammation. Eur Heart J. 2010 Aug; 31(16):1975-84.
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  174. Swirski FK, Wildgruber M, Ueno T, Figueiredo JL, Panizzi P, Iwamoto Y, Zhang E, Stone JR, Rodriguez E, Chen JW, Pittet MJ, Weissleder R, Nahrendorf M. Myeloperoxidase-rich Ly-6C+ myeloid cells infiltrate allografts and contribute to an imaging signature of organ rejection in mice. J Clin Invest. 2010 Jul; 120(7):2627-34.
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  175. Han HS, Devaraj NK, Lee J, Hilderbrand SA, Weissleder R, Bawendi MG. Development of a bioorthogonal and highly efficient conjugation method for quantum dots using tetrazine-norbornene cycloaddition. J Am Chem Soc. 2010 Jun 16; 132(23):7838-9.
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  176. Taniguchi CM, Winnay J, Kondo T, Bronson RT, Guimaraes AR, Alemán JO, Luo J, Stephanopoulos G, Weissleder R, Cantley LC, Kahn CR. The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling. Cancer Res. 2010 Jul 1; 70(13):5305-15.
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  177. Haun JB, Yoon TJ, Lee H, Weissleder R. Magnetic nanoparticle biosensors. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010 May-Jun; 2(3):291-304.
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  178. Libby P, DiCarli M, Weissleder R. The vascular biology of atherosclerosis and imaging targets. J Nucl Med. 2010 May 1; 51 Suppl 1:33S-37S.
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  179. Panizzi P, Swirski FK, Figueiredo JL, Waterman P, Sosnovik DE, Aikawa E, Libby P, Pittet M, Weissleder R, Nahrendorf M. Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis. J Am Coll Cardiol. 2010 Apr 13; 55(15):1629-38.
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  180. Nahrendorf M, Keliher E, Marinelli B, Waterman P, Feruglio PF, Fexon L, Pivovarov M, Swirski FK, Pittet MJ, Vinegoni C, Weissleder R. Hybrid PET-optical imaging using targeted probes. Proc Natl Acad Sci U S A. 2010 Apr 27; 107(17):7910-5.
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  181. Bratlie KM, Dang TT, Lyle S, Nahrendorf M, Weissleder R, Langer R, Anderson DG. Rapid biocompatibility analysis of materials via in vivo fluorescence imaging of mouse models. PLoS One. 2010; 5(4):e10032.
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  182. Hingtgen SD, Kasmieh R, van de Water J, Weissleder R, Shah K. A novel molecule integrating therapeutic and diagnostic activities reveals multiple aspects of stem cell-based therapy. Stem Cells. 2010 Apr; 28(4):832-41.
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  183. Vinegoni C, Fumene Feruglio P, Cortez-Retamozo V, Razansky D, Medoff BD, Ntziachristos V, Sbarbati A, Pittet M, Weissleder R. Imaging of molecular probe activity with Born-normalized fluorescence optical projection tomography. Opt Lett. 2010 Apr 1; 35(7):1088-90.
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  184. van Eekelen M, Sasportas LS, Kasmieh R, Yip S, Figueiredo JL, Louis DN, Weissleder R, Shah K. Human stem cells expressing novel TSP-1 variant have anti-angiogenic effect on brain tumors. Oncogene. 2010 Jun 3; 29(22):3185-95.
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  185. Devaraj NK, Hilderbrand S, Upadhyay R, Mazitschek R, Weissleder R. Bioorthogonal turn-on probes for imaging small molecules inside living cells. Angew Chem Int Ed Engl. 2010 Apr 6; 49(16):2869-72.
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  186. Kirsch DG, Grimm J, Guimaraes AR, Wojtkiewicz GR, Perez BA, Santiago PM, Anthony NK, Forbes T, Doppke K, Weissleder R, Jacks T. Imaging primary lung cancers in mice to study radiation biology. Int J Radiat Oncol Biol Phys. 2010 Mar 15; 76(4):973-7.
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  187. Vallet S, Mukherjee S, Vaghela N, Hideshima T, Fulciniti M, Pozzi S, Santo L, Cirstea D, Patel K, Sohani AR, Guimaraes A, Xie W, Chauhan D, Schoonmaker JA, Attar E, Churchill M, Weller E, Munshi N, Seehra JS, Weissleder R, Anderson KC, Scadden DT, Raje N. Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease. Proc Natl Acad Sci U S A. 2010 Mar 16; 107(11):5124-9.
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  188. Figueiredo JL, Siegel C, Nahrendorf M, Weissleder R. Intraoperative near-infrared fluorescent cholangiography (NIRFC) in mouse models of bile duct injury. World J Surg. 2010 Feb; 34(2):336-43.
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  189. Zhong L, D'Urso A, Toiber D, Sebastian C, Henry RE, Vadysirisack DD, Guimaraes A, Marinelli B, Wikstrom JD, Nir T, Clish CB, Vaitheesvaran B, Iliopoulos O, Kurland I, Dor Y, Weissleder R, Shirihai OS, Ellisen LW, Espinosa JM, Mostoslavsky R. The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha. Cell. 2010 Jan 22; 140(2):280-93.
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  190. Rodríguez E, Nilges M, Weissleder R, Chen JW. Activatable magnetic resonance imaging agents for myeloperoxidase sensing: mechanism of activation, stability, and toxicity. J Am Chem Soc. 2010 Jan 13; 132(1):168-77.
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  191. Hamilton AM, Rogers KA, Belisle AJ, Ronald JA, Rutt BK, Weissleder R, Boughner DR. Early identification of aortic valve sclerosis using iron oxide enhanced MRI. J Magn Reson Imaging. 2010 Jan; 31(1):110-6.
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  192. Libby P, Nahrendorf M, Weissleder R. Molecular imaging of atherosclerosis: a progress report. Tex Heart Inst J. 2010; 37(3):324-7.
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  193. Tassa C, Duffner JL, Lewis TA, Weissleder R, Schreiber SL, Koehler AN, Shaw SY. Binding affinity and kinetic analysis of targeted small molecule-modified nanoparticles. Bioconjug Chem. 2010 Jan; 21(1):14-9.
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  194. Vinegoni C, Fexon L, Feruglio PF, Pivovarov M, Figueiredo JL, Nahrendorf M, Pozzo A, Sbarbati A, Weissleder R. High throughput transmission optical projection tomography using low cost graphics processing unit. Opt Express. 2009 Dec 7; 17(25):22320-32.
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  195. Thurber GM, Figueiredo JL, Weissleder R. Multicolor fluorescent intravital live microscopy (FILM) for surgical tumor resection in a mouse xenograft model. PLoS One. 2009; 4(11):e8053.
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  196. Tsai CC, Vinegoni C, Weissleder R. Diffractionless beam in free space with adiabatic changing refractive index in a single mode tapered slab waveguide. Opt Express. 2009 Nov 23; 17(24):21723-31.
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  197. Panizzi P, Nahrendorf M, Wildgruber M, Waterman P, Figueiredo JL, Aikawa E, McCarthy J, Weissleder R, Hilderbrand SA. Oxazine conjugated nanoparticle detects in vivo hypochlorous acid and peroxynitrite generation. J Am Chem Soc. 2009 Nov 4; 131(43):15739-44.
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  198. Smith RA, Yuan H, Weissleder R, Cantley LC, Josephson L. A wortmannin-cetuximab as a double drug. Bioconjug Chem. 2009 Nov; 20(11):2185-9.
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  199. Hilderbrand SA, Weissleder R. Near-infrared fluorescence: application to in vivo molecular imaging. Curr Opin Chem Biol. 2010 Feb; 14(1):71-9.
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  200. Hardcastle J, Kurozumi K, Dmitrieva N, Sayers MP, Ahmad S, Waterman P, Weissleder R, Chiocca EA, Kaur B. Enhanced antitumor efficacy of vasculostatin (Vstat120) expressing oncolytic HSV-1. Mol Ther. 2010 Feb; 18(2):285-94.
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  201. Duchrow T, Shtatland T, Guettler D, Pivovarov M, Kramer S, Weissleder R. Enhancing navigation in biomedical databases by community voting and database-driven text classification. BMC Bioinformatics. 2009; 10:317.
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  202. Martinez-Boubeta C, Balcells L, Cristòfol R, Sanfeliu C, Rodríguez E, Weissleder R, Lope-Piedrafita S, Simeonidis K, Angelakeris M, Sandiumenge F, Calleja A, Casas L, Monty C, Martínez B. Self-assembled multifunctional Fe/MgO nanospheres for magnetic resonance imaging and hyperthermia. Nanomedicine. 2010 Apr; 6(2):362-70.
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  203. Nahrendorf M, Keliher E, Panizzi P, Zhang H, Hembrador S, Figueiredo JL, Aikawa E, Kelly K, Libby P, Weissleder R. 18F-4V for PET-CT imaging of VCAM-1 expression in atherosclerosis. JACC Cardiovasc Imaging. 2009 Oct; 2(10):1213-22.
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  204. Sosnovik DE, Garanger E, Aikawa E, Nahrendorf M, Figuiredo JL, Dai G, Reynolds F, Rosenzweig A, Weissleder R, Josephson L. Molecular MRI of cardiomyocyte apoptosis with simultaneous delayed-enhancement MRI distinguishes apoptotic and necrotic myocytes in vivo: potential for midmyocardial salvage in acute ischemia. Circ Cardiovasc Imaging. 2009 Nov; 2(6):460-7.
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  205. Vinegoni C, Razansky D, Hilderbrand SA, Shao F, Ntziachristos V, Weissleder R. Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles. Opt Lett. 2009 Sep 1; 34(17):2566-8.
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  206. Sosnovik DE, Nahrendorf M, Panizzi P, Matsui T, Aikawa E, Dai G, Li L, Reynolds F, Dorn GW, Weissleder R, Josephson L, Rosenzweig A. Molecular MRI detects low levels of cardiomyocyte apoptosis in a transgenic model of chronic heart failure. Circ Cardiovasc Imaging. 2009 Nov; 2(6):468-75.
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  207. Bhaumik J, Weissleder R, McCarthy JR. Synthesis and photophysical properties of sulfonamidophenyl porphyrins as models for activatable photosensitizers. J Org Chem. 2009 Aug 21; 74(16):5894-901.
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  208. Vinegoni C, Razansky D, Pitsouli C, Perrimon N, Ntziachristos V, Weissleder R. Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila. J Vis Exp. 2009; (30).
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  209. Ronald JA, Chen JW, Chen Y, Hamilton AM, Rodriguez E, Reynolds F, Hegele RA, Rogers KA, Querol M, Bogdanov A, Weissleder R, Rutt BK. Enzyme-sensitive magnetic resonance imaging targeting myeloperoxidase identifies active inflammation in experimental rabbit atherosclerotic plaques. Circulation. 2009 Aug 18; 120(7):592-9.
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  210. Stangenberg L, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A, Yuan H, Blois J, Smith RA, Yaffe MB, Weissleder R, Benoist C, Mathis D, Josephson L, Mahmood U. Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function. Arthritis Rheum. 2009 Aug; 60(8):2314-24.
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  211. Rajendran R, Ronald JA, Ye T, Minqin R, Chen JW, Weissleder R, Rutt BK, Halliwell B, Watt F. Nuclear microscopy: a novel technique for quantitative imaging of gadolinium distribution within tissue sections. Microsc Microanal. 2009 Aug; 15(4):338-44.
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  212. Vonken EJ, Korosoglou G, Yu J, Schär M, Weissleder R, Stuber M. On the dual contrast enhancement mechanism in frequency-selective inversion-recovery magnetic resonance angiography (IRON-MRA). Magn Reson Med. 2009 Aug; 62(2):314-24.
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  213. Swirski FK, Nahrendorf M, Etzrodt M, Wildgruber M, Cortez-Retamozo V, Panizzi P, Figueiredo JL, Kohler RH, Chudnovskiy A, Waterman P, Aikawa E, Mempel TR, Libby P, Weissleder R, Pittet MJ. Identification of splenic reservoir monocytes and their deployment to inflammatory sites. Science. 2009 Jul 31; 325(5940):612-6.
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  214. Lee H, Yoon TJ, Figueiredo JL, Swirski FK, Weissleder R. Rapid detection and profiling of cancer cells in fine-needle aspirates. Proc Natl Acad Sci U S A. 2009 Jul 28; 106(30):12459-64.
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  215. Nahrendorf M, Waterman P, Thurber G, Groves K, Rajopadhye M, Panizzi P, Marinelli B, Aikawa E, Pittet MJ, Swirski FK, Weissleder R. Hybrid in vivo FMT-CT imaging of protease activity in atherosclerosis with customized nanosensors. Arterioscler Thromb Vasc Biol. 2009 Oct; 29(10):1444-51.
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  216. Yoon SS, Stangenberg L, Lee YJ, Rothrock C, Dreyfuss JM, Baek KH, Waterman PR, Nielsen GP, Weissleder R, Mahmood U, Park PJ, Jacks T, Dodd RD, Fisher CJ, Ryeom S, Kirsch DG. Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma. Int J Radiat Oncol Biol Phys. 2009 Jul 15; 74(4):1207-16.
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  217. McCarthy JR, Bhaumik J, Merbouh N, Weissleder R. High-yielding syntheses of hydrophilic conjugatable chlorins and bacteriochlorins. Org Biomol Chem. 2009 Sep 7; 7(17):3430-6.
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  218. Ross RW, Zietman AL, Xie W, Coen JJ, Dahl DM, Shipley WU, Kaufman DS, Islam T, Guimaraes AR, Weissleder R, Harisinghani M. Lymphotropic nanoparticle-enhanced magnetic resonance imaging (LNMRI) identifies occult lymph node metastases in prostate cancer patients prior to salvage radiation therapy. Clin Imaging. 2009 Jul-Aug; 33(4):301-5.
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  219. Garanger E, Hilderbrand SA, Blois JT, Sosnovik DE, Weissleder R, Josephson L. A DNA-binding Gd chelate for the detection of cell death by MRI. Chem Commun (Camb). 2009 Aug 7; (29):4444-6.
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  220. Hilderbrand SA, Shao F, Salthouse C, Mahmood U, Weissleder R. Upconverting luminescent nanomaterials: application to in vivo bioimaging. Chem Commun (Camb). 2009 Jul 28; (28):4188-90.
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  221. Smith A, Blois J, Yuan H, Aikawa E, Ellson C, Figueiredo JL, Weissleder R, Kohler R, Yaffe MB, Cantley LC, Josephson L. The antiproliferative cytostatic effects of a self-activating viridin prodrug. Mol Cancer Ther. 2009 Jun; 8(6):1666-75.
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  222. Vinegoni C, Razansky D, Figueiredo JL, Fexon L, Pivovarov M, Nahrendorf M, Ntziachristos V, Weissleder R. Born normalization for fluorescence optical projection tomography for whole heart imaging. J Vis Exp. 2009; (28).
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  223. McCarthy JR, Patel P, Botnaru I, Haghayeghi P, Weissleder R, Jaffer FA. Multimodal nanoagents for the detection of intravascular thrombi. Bioconjug Chem. 2009 Jun; 20(6):1251-5.
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  224. Yuan H, Pupo MT, Blois J, Smith A, Weissleder R, Clardy J, Josephson L. A stabilized demethoxyviridin derivative inhibits PI3 kinase. Bioorg Med Chem Lett. 2009 Aug 1; 19(15):4223-7.
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  225. Wildgruber M, Lee H, Chudnovskiy A, Yoon TJ, Etzrodt M, Pittet MJ, Nahrendorf M, Croce K, Libby P, Weissleder R, Swirski FK. Monocyte subset dynamics in human atherosclerosis can be profiled with magnetic nano-sensors. PLoS One. 2009; 4(5):e5663.
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  226. Figueiredo JL, Nahrendorf M, Sosnovik DE, Weissleder R. MRI of a novel murine working heart transplant model. Circ Heart Fail. 2009 May; 2(3):272-4.
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  227. Koh I, Hong R, Weissleder R, Josephson L. Nanoparticle-target interactions parallel antibody-protein interactions. Anal Chem. 2009 May 1; 81(9):3618-22.
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  228. Leimgruber A, Berger C, Cortez-Retamozo V, Etzrodt M, Newton AP, Waterman P, Figueiredo JL, Kohler RH, Elpek N, Mempel TR, Swirski FK, Nahrendorf M, Weissleder R, Pittet MJ. Behavior of endogenous tumor-associated macrophages assessed in vivo using a functionalized nanoparticle. Neoplasia. 2009 May; 11(5):459-68, 2 p following 468.
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  229. Bullain SS, Sahin A, Szentirmai O, Sanchez C, Lin N, Baratta E, Waterman P, Weissleder R, Mulligan RC, Carter BS. Genetically engineered T cells to target EGFRvIII expressing glioblastoma. J Neurooncol. 2009 Sep; 94(3):373-82.
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  230. Swirski FK, Weissleder R, Pittet MJ. Heterogeneous in vivo behavior of monocyte subsets in atherosclerosis. Arterioscler Thromb Vasc Biol. 2009 Oct; 29(10):1424-32.
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  231. Daniel KD, Kim GY, Vassiliou CC, Galindo M, Guimaraes AR, Weissleder R, Charest A, Langer R, Cima MJ. Implantable diagnostic device for cancer monitoring. Biosens Bioelectron. 2009 Jul 15; 24(11):3252-7.
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  232. Jaffer FA, Libby P, Weissleder R. Optical and multimodality molecular imaging: insights into atherosclerosis. Arterioscler Thromb Vasc Biol. 2009 Jul; 29(7):1017-24.
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  233. Christen T, Nahrendorf M, Wildgruber M, Swirski FK, Aikawa E, Waterman P, Shimizu K, Weissleder R, Libby P. Molecular imaging of innate immune cell function in transplant rejection. Circulation. 2009 Apr 14; 119(14):1925-32.
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  234. Aikawa E, Aikawa M, Libby P, Figueiredo JL, Rusanescu G, Iwamoto Y, Fukuda D, Kohler RH, Shi GP, Jaffer FA, Weissleder R. Arterial and aortic valve calcification abolished by elastolytic cathepsin S deficiency in chronic renal disease. Circulation. 2009 Apr 7; 119(13):1785-94.
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  235. Sasportas LS, Kasmieh R, Wakimoto H, Hingtgen S, van de Water JA, Mohapatra G, Figueiredo JL, Martuza RL, Weissleder R, Shah K. Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy. Proc Natl Acad Sci U S A. 2009 Mar 24; 106(12):4822-7.
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  236. Tannous BA, Christensen AP, Pike L, Wurdinger T, Perry KF, Saydam O, Jacobs AH, García-Añoveros J, Weissleder R, Sena-Esteves M, Corey DP, Breakefield XO. Mutant sodium channel for tumor therapy. Mol Ther. 2009 May; 17(5):810-9.
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  237. Kelly KA, Shaw SY, Nahrendorf M, Kristoff K, Aikawa E, Schreiber SL, Clemons PA, Weissleder R. Unbiased discovery of in vivo imaging probes through in vitro profiling of nanoparticle libraries. Integr Biol (Camb). 2009 Apr; 1(4):311-7.
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  238. Zhu H, Acquaviva J, Ramachandran P, Boskovitz A, Woolfenden S, Pfannl R, Bronson RT, Chen JW, Weissleder R, Housman DE, Charest A. Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis. Proc Natl Acad Sci U S A. 2009 Feb 24; 106(8):2712-6.
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  239. Devaraj NK, Keliher EJ, Thurber GM, Nahrendorf M, Weissleder R. 18F labeled nanoparticles for in vivo PET-CT imaging. Bioconjug Chem. 2009 Feb; 20(2):397-401.
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  240. Vinegoni C, Razansky D, Figueiredo JL, Nahrendorf M, Ntziachristos V, Weissleder R. Normalized Born ratio for fluorescence optical projection tomography. Opt Lett. 2009 Feb 1; 34(3):319-21.
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  241. Sheth RA, Upadhyay R, Stangenberg L, Sheth R, Weissleder R, Mahmood U. Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model. Gynecol Oncol. 2009 Mar; 112(3):616-22.
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  242. Garanger E, Weissleder R, Josephson L. A multifunctional single-attachment-point reagent for controlled protein biotinylation. Bioconjug Chem. 2009 Jan; 20(1):170-3.
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  243. Lee H, Yoon TJ, Weissleder R. Ultrasensitive detection of bacteria using core-shell nanoparticles and an NMR-filter system. Angew Chem Int Ed Engl. 2009; 48(31):5657-60.
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  244. Devaraj NK, Upadhyay R, Haun JB, Hilderbrand SA, Weissleder R. Fast and sensitive pretargeted labeling of cancer cells through a tetrazine/trans-cyclooctene cycloaddition. Angew Chem Int Ed Engl. 2009; 48(38):7013-6.
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  245. McCann CM, Waterman P, Figueiredo JL, Aikawa E, Weissleder R, Chen JW. Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy. Neuroimage. 2009 Apr 1; 45(2):360-9.
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  246. Salthouse C, Hildebrand S, Weissleder R, Mahmood U. Design and demonstration of a small-animal up-conversion imager. Opt Express. 2008 Dec 22; 16(26):21731-7.
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  247. Jeong JH, Wang Z, Guimaraes AS, Ouyang X, Figueiredo JL, Ding Z, Jiang S, Guney I, Kang GH, Shin E, Hahn WC, Loda MF, Abate-Shen C, Weissleder R, Chin L. BRAF activation initiates but does not maintain invasive prostate adenocarcinoma. PLoS One. 2008; 3(12):e3949.
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  248. Devaraj NK, Weissleder R, Hilderbrand SA. Tetrazine-based cycloadditions: application to pretargeted live cell imaging. Bioconjug Chem. 2008 Dec; 19(12):2297-9.
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  249. Shao F, Weissleder R, Hilderbrand SA. Monofunctional carbocyanine dyes for bio- and bioorthogonal conjugation. Bioconjug Chem. 2008 Dec; 19(12):2487-91.
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  250. Engelman JA, Chen L, Tan X, Crosby K, Guimaraes AR, Upadhyay R, Maira M, McNamara K, Perera SA, Song Y, Chirieac LR, Kaur R, Lightbown A, Simendinger J, Li T, Padera RF, García-Echeverría C, Weissleder R, Mahmood U, Cantley LC, Wong KK. Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. Nat Med. 2008 Dec; 14(12):1351-6.
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  251. Niedre MJ, de Kleine RH, Aikawa E, Kirsch DG, Weissleder R, Ntziachristos V. Early photon tomography allows fluorescence detection of lung carcinomas and disease progression in mice in vivo. Proc Natl Acad Sci U S A. 2008 Dec 9; 105(49):19126-31.
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  252. Breckwoldt MO, Chen JW, Stangenberg L, Aikawa E, Rodriguez E, Qiu S, Moskowitz MA, Weissleder R. Tracking the inflammatory response in stroke in vivo by sensing the enzyme myeloperoxidase. Proc Natl Acad Sci U S A. 2008 Nov 25; 105(47):18584-9.
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  253. Cortez-Retamozo V, Swirski FK, Waterman P, Yuan H, Figueiredo JL, Newton AP, Upadhyay R, Vinegoni C, Kohler R, Blois J, Smith A, Nahrendorf M, Josephson L, Weissleder R, Pittet MJ. Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation. J Clin Invest. 2008 Dec; 118(12):4058-66.
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  254. Würdinger T, Tannous BA, Saydam O, Skog J, Grau S, Soutschek J, Weissleder R, Breakefield XO, Krichevsky AM. miR-296 regulates growth factor receptor overexpression in angiogenic endothelial cells. Cancer Cell. 2008 Nov 4; 14(5):382-93.
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  255. Hingtgen S, Ren X, Terwilliger E, Classon M, Weissleder R, Shah K. Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide. Mol Cancer Ther. 2008 Nov; 7(11):3575-85.
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  256. Guimaraes AR, Rakhlin E, Weissleder R, Thayer SP. Magnetic resonance imaging monitors physiological changes with antihedgehog therapy in pancreatic adenocarcinoma xenograft model. Pancreas. 2008 Nov; 37(4):440-4.
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  257. Kozloff KM, Quinti L, Patntirapong S, Hauschka PV, Tung CH, Weissleder R, Mahmood U. Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo. Bone. 2009 Feb; 44(2):190-8.
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  258. Girnun GD, Chen L, Silvaggi J, Drapkin R, Chirieac LR, Padera RF, Upadhyay R, Vafai SB, Weissleder R, Mahmood U, Naseri E, Buckley S, Li D, Force J, McNamara K, Demetri G, Spiegelman BM, Wong KK. Regression of drug-resistant lung cancer by the combination of rosiglitazone and carboplatin. Clin Cancer Res. 2008 Oct 15; 14(20):6478-86.
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  259. Jaffer FA, Vinegoni C, John MC, Aikawa E, Gold HK, Finn AV, Ntziachristos V, Libby P, Weissleder R. Real-time catheter molecular sensing of inflammation in proteolytically active atherosclerosis. Circulation. 2008 Oct 28; 118(18):1802-9.
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  260. Perez JM, Grimm J, Josephson L, Weissleder R. Integrated nanosensors to determine levels and functional activity of human telomerase. Neoplasia. 2008 Oct; 10(10):1066-72.
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  261. Korosoglou G, Shah S, Vonken EJ, Gilson WD, Schär M, Tang L, Kraitchman DL, Boston RC, Sosnovik DE, Weiss RG, Weissleder R, Stuber M. Off-resonance angiography: a new method to depict vessels--phantom and rabbit studies. Radiology. 2008 Nov; 249(2):501-9.
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  262. Salthouse CD, Weissleder R, Mahmood U. Development of a time domain fluorimeter for fluorescent lifetime multiplexing analysis. IEEE Trans Biomed Circuits Syst. 2008 Sep 1; 2(3):204-11.
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  263. Gounaris E, Tung CH, Restaino C, Maehr R, Kohler R, Joyce JA, Ploegh HL, Plough HL, Barrett TA, Weissleder R, Khazaie K. Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth. PLoS One. 2008; 3(8):e2916.
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  264. Garanger E, Aikawa E, Reynolds F, Weissleder R, Josephson L. Simplified syntheses of complex multifunctional nanomaterials. Chem Commun (Camb). 2008 Oct 21; (39):4792-4.
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  265. Korosoglou G, Weiss RG, Kedziorek DA, Walczak P, Gilson WD, Schär M, Sosnovik DE, Kraitchman DL, Boston RC, Bulte JW, Weissleder R, Stuber M. Noninvasive detection of macrophage-rich atherosclerotic plaque in hyperlipidemic rabbits using "positive contrast" magnetic resonance imaging. J Am Coll Cardiol. 2008 Aug 5; 52(6):483-91.
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  266. Sosnovik DE, Nahrendorf M, Weissleder R. Targeted imaging of myocardial damage. Nat Clin Pract Cardiovasc Med. 2008 Aug; 5 Suppl 2:S63-70.
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  267. Rusanescu G, Weissleder R, Aikawa E. Notch signaling in cardiovascular disease and calcification. Curr Cardiol Rev. 2008 Aug; 4(3):148-56.
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  268. Hilderbrand SA, Kelly KA, Niedre M, Weissleder R. Near infrared fluorescence-based bacteriophage particles for ratiometric pH imaging. Bioconjug Chem. 2008 Aug; 19(8):1635-9.
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  269. Gee MS, Upadhyay R, Bergquist H, Alencar H, Reynolds F, Maricevich M, Weissleder R, Josephson L, Mahmood U. Human breast cancer tumor models: molecular imaging of drug susceptibility and dosing during HER2/neu-targeted therapy. Radiology. 2008 Sep; 248(3):925-35.
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  270. Blois J, Yuan H, Smith A, Pacold ME, Weissleder R, Cantley LC, Josephson L. Slow self-activation enhances the potency of viridin prodrugs. J Med Chem. 2008 Aug 14; 51(15):4699-707.
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  271. Lee H, Sun E, Ham D, Weissleder R. Chip-NMR biosensor for detection and molecular analysis of cells. Nat Med. 2008 Aug; 14(8):869-74.
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  272. Lin KY, Maricevich M, Bardeesy N, Weissleder R, Mahmood U. In vivo quantitative microvasculature phenotype imaging of healthy and malignant tissues using a fiber-optic confocal laser microprobe. Transl Oncol. 2008 Jul; 1(2):84-94.
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  273. Taktak S, Weissleder R, Josephson L. Electrode chemistry yields a nanoparticle-based NMR sensor for calcium. Langmuir. 2008 Jul 15; 24(14):7596-8.
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  274. Farrar CT, Dai G, Novikov M, Rosenzweig A, Weissleder R, Rosen BR, Sosnovik DE. Impact of field strength and iron oxide nanoparticle concentration on the linearity and diagnostic accuracy of off-resonance imaging. NMR Biomed. 2008 Jun; 21(5):453-63.
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  275. Korngold EC, Jaffer FA, Weissleder R, Sosnovik DE. Noninvasive imaging of apoptosis in cardiovascular disease. Heart Fail Rev. 2008 Jun; 13(2):163-73.
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  276. Shaw SY, Westly EC, Pittet MJ, Subramanian A, Schreiber SL, Weissleder R. Perturbational profiling of nanomaterial biologic activity. Proc Natl Acad Sci U S A. 2008 May 27; 105(21):7387-92.
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  277. Shah K, Hingtgen S, Kasmieh R, Figueiredo JL, Garcia-Garcia E, Martinez-Serrano A, Breakefield X, Weissleder R. Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model. J Neurosci. 2008 Apr 23; 28(17):4406-13.
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  278. Kelly KA, Bardeesy N, Anbazhagan R, Gurumurthy S, Berger J, Alencar H, Depinho RA, Mahmood U, Weissleder R. Targeted nanoparticles for imaging incipient pancreatic ductal adenocarcinoma. PLoS Med. 2008 Apr 15; 5(4):e85.
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  279. McCarthy JR, Weissleder R. Multifunctional magnetic nanoparticles for targeted imaging and therapy. Adv Drug Deliv Rev. 2008 Aug 17; 60(11):1241-51.
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  280. Weissleder R, Pittet MJ. Imaging in the era of molecular oncology. Nature. 2008 Apr 3; 452(7187):580-9.
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  281. Kelly KA, Setlur SR, Ross R, Anbazhagan R, Waterman P, Rubin MA, Weissleder R. Detection of early prostate cancer using a hepsin-targeted imaging agent. Cancer Res. 2008 Apr 1; 68(7):2286-91.
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  282. Figueiredo JL, Passerotti CC, Sponholtz T, Nguyen HT, Weissleder R. A novel method of imaging calcium urolithiasis using fluorescence. J Urol. 2008 Apr; 179(4):1610-4.
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  283. Guimaraes AR, Tabatabei S, Dahl D, McDougal WS, Weissleder R, Harisinghani MG. Pilot study evaluating use of lymphotrophic nanoparticle-enhanced magnetic resonance imaging for assessing lymph nodes in renal cell cancer. Urology. 2008 Apr; 71(4):708-12.
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  284. Hong R, Cima MJ, Weissleder R, Josephson L. Magnetic microparticle aggregation for viscosity determination by MR. Magn Reson Med. 2008 Mar; 59(3):515-20.
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  285. Nahrendorf M, Sosnovik DE, Weissleder R. MR-optical imaging of cardiovascular molecular targets. Basic Res Cardiol. 2008 Mar; 103(2):87-94.
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  286. Sosnovik DE, Nahrendorf M, Weissleder R. Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications. Basic Res Cardiol. 2008 Mar; 103(2):122-30.
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  287. Nahrendorf M, Sosnovik D, Chen JW, Panizzi P, Figueiredo JL, Aikawa E, Libby P, Swirski FK, Weissleder R. Activatable magnetic resonance imaging agent reports myeloperoxidase activity in healing infarcts and noninvasively detects the antiinflammatory effects of atorvastatin on ischemia-reperfusion injury. Circulation. 2008 Mar 4; 117(9):1153-60.
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  288. Nahrendorf M, Aikawa E, Figueiredo JL, Stangenberg L, van den Borne SW, Blankesteijn WM, Sosnovik DE, Jaffer FA, Tung CH, Weissleder R. Transglutaminase activity in acute infarcts predicts healing outcome and left ventricular remodelling: implications for FXIII therapy and antithrombin use in myocardial infarction. Eur Heart J. 2008 Feb; 29(4):445-54.
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  289. Chen JW, Breckwoldt MO, Aikawa E, Chiang G, Weissleder R. Myeloperoxidase-targeted imaging of active inflammatory lesions in murine experimental autoimmune encephalomyelitis. Brain. 2008 Apr; 131(Pt 4):1123-33.
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  290. Wurdinger T, Badr C, Pike L, de Kleine R, Weissleder R, Breakefield XO, Tannous BA. A secreted luciferase for ex vivo monitoring of in vivo processes. Nat Methods. 2008 Feb; 5(2):171-3.
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  291. Kircher MF, Grimm J, Swirski FK, Libby P, Gerszten RE, Allport JR, Weissleder R. Noninvasive in vivo imaging of monocyte trafficking to atherosclerotic lesions. Circulation. 2008 Jan 22; 117(3):388-95.
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  292. Koh I, Hong R, Weissleder R, Josephson L. Sensitive NMR sensors detect antibodies to influenza. Angew Chem Int Ed Engl. 2008; 47(22):4119-21.
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  293. Nahrendorf M, Zhang H, Hembrador S, Panizzi P, Sosnovik DE, Aikawa E, Libby P, Swirski FK, Weissleder R. Nanoparticle PET-CT imaging of macrophages in inflammatory atherosclerosis. Circulation. 2008 Jan 22; 117(3):379-87.
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  294. Bouffard J, Kim Y, Swager TM, Weissleder R, Hilderbrand SA. A highly selective fluorescent probe for thiol bioimaging. Org Lett. 2008 Jan 3; 10(1):37-40.
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  295. Gounaris E, Erdman SE, Restaino C, Gurish MF, Friend DS, Gounari F, Lee DM, Zhang G, Glickman JN, Shin K, Rao VP, Poutahidis T, Weissleder R, McNagny KM, Khazaie K. Mast cells are an essential hematopoietic component for polyp development. Proc Natl Acad Sci U S A. 2007 Dec 11; 104(50):19977-82.
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  296. Gee MS, Upadhyay R, Bergquist H, Weissleder R, Josephson L, Mahmood U. Multiparameter noninvasive assessment of treatment susceptibility, drug target inhibition and tumor response guides cancer treatment. Int J Cancer. 2007 Dec 1; 121(11):2492-500.
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  297. Harisinghani M, Ross RW, Guimaraes AR, Weissleder R. Utility of a new bolus-injectable nanoparticle for clinical cancer staging. Neoplasia. 2007 Dec; 9(12):1160-5.
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  298. Kurozumi K, Hardcastle J, Thakur R, Yang M, Christoforidis G, Fulci G, Hochberg FH, Weissleder R, Carson W, Chiocca EA, Kaur B. Effect of tumor microenvironment modulation on the efficacy of oncolytic virus therapy. J Natl Cancer Inst. 2007 Dec 5; 99(23):1768-81.
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  299. Aikawa E, Nahrendorf M, Figueiredo JL, Swirski FK, Shtatland T, Kohler RH, Jaffer FA, Aikawa M, Weissleder R. Osteogenesis associates with inflammation in early-stage atherosclerosis evaluated by molecular imaging in vivo. Circulation. 2007 Dec 11; 116(24):2841-50.
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  300. Nahrendorf M, Swirski FK, Aikawa E, Stangenberg L, Wurdinger T, Figueiredo JL, Libby P, Weissleder R, Pittet MJ. The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med. 2007 Nov 26; 204(12):3037-47.
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  301. Barnes KR, Blois J, Smith A, Yuan H, Reynolds F, Weissleder R, Cantley LC, Josephson L. Fate of a bioactive fluorescent wortmannin derivative in cells. Bioconjug Chem. 2008 Jan; 19(1):130-7.
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  302. Taktak S, Sosnovik D, Cima MJ, Weissleder R, Josephson L. Multiparameter magnetic relaxation switch assays. Anal Chem. 2007 Dec 1; 79(23):8863-9.
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  303. Upadhyay R, Sheth RA, Weissleder R, Mahmood U. Quantitative real-time catheter-based fluorescence molecular imaging in mice. Radiology. 2007 Nov; 245(2):523-31.
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  304. Shepherd J, Hilderbrand SA, Waterman P, Heinecke JW, Weissleder R, Libby P. A fluorescent probe for the detection of myeloperoxidase activity in atherosclerosis-associated macrophages. Chem Biol. 2007 Nov; 14(11):1221-31.
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  305. Swirski FK, Berger CR, Figueiredo JL, Mempel TR, von Andrian UH, Pittet MJ, Weissleder R. A near-infrared cell tracker reagent for multiscopic in vivo imaging and quantification of leukocyte immune responses. PLoS One. 2007; 2(10):e1075.
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  306. Law B, Weissleder R, Tung CH. Protease-sensitive fluorescent nanofibers. Bioconjug Chem. 2007 Nov-Dec; 18(6):1701-4.
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  307. Fulci G, Dmitrieva N, Gianni D, Fontana EJ, Pan X, Lu Y, Kaufman CS, Kaur B, Lawler SE, Lee RJ, Marsh CB, Brat DJ, van Rooijen N, Stemmer-Rachamimov AO, Rachamimov AS, Hochberg FH, Weissleder R, Martuza RL, Chiocca EA. Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses. Cancer Res. 2007 Oct 1; 67(19):9398-406.
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  308. Corsten MF, Miranda R, Kasmieh R, Krichevsky AM, Weissleder R, Shah K. MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas. Cancer Res. 2007 Oct 1; 67(19):8994-9000.
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  309. Jaffer FA, Libby P, Weissleder R. Molecular imaging of cardiovascular disease. Circulation. 2007 Aug 28; 116(9):1052-61.
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  310. Kirsch DG, Dinulescu DM, Miller JB, Grimm J, Santiago PM, Young NP, Nielsen GP, Quade BJ, Chaber CJ, Schultz CP, Takeuchi O, Bronson RT, Crowley D, Korsmeyer SJ, Yoon SS, Hornicek FJ, Weissleder R, Jacks T. A spatially and temporally restricted mouse model of soft tissue sarcoma. Nat Med. 2007 Aug; 13(8):992-7.
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  311. Kozloff KM, Weissleder R, Mahmood U. Noninvasive optical detection of bone mineral. J Bone Miner Res. 2007 Aug; 22(8):1208-16.
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  312. Arwert E, Hingtgen S, Figueiredo JL, Bergquist H, Mahmood U, Weissleder R, Shah K. Visualizing the dynamics of EGFR activity and antiglioma therapies in vivo. Cancer Res. 2007 Aug 1; 67(15):7335-42.
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  313. Shtatland T, Guettler D, Kossodo M, Pivovarov M, Weissleder R. PepBank--a database of peptides based on sequence text mining and public peptide data sources. BMC Bioinformatics. 2007; 8:280.
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  314. Kelly KA, Carson J, McCarthy JR, Weissleder R. Novel peptide sequence ("IQ-tag") with high affinity for NIR fluorochromes allows protein and cell specific labeling for in vivo imaging. PLoS One. 2007; 2(7):e665.
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  315. Wu HJ, Sawaya H, Binstadt B, Brickelmaier M, Blasius A, Gorelik L, Mahmood U, Weissleder R, Carulli J, Benoist C, Mathis D. Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk. J Exp Med. 2007 Aug 6; 204(8):1911-22.
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  316. Kim Y, Choi Y, Weissleder R, Tung CH. Membrane permeable esterase-activated fluorescent imaging probe. Bioorg Med Chem Lett. 2007 Sep 15; 17(18):5054-7.
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  317. Pittet MJ, Grimm J, Berger CR, Tamura T, Wojtkiewicz G, Nahrendorf M, Romero P, Swirski FK, Weissleder R. In vivo imaging of T cell delivery to tumors after adoptive transfer therapy. Proc Natl Acad Sci U S A. 2007 Jul 24; 104(30):12457-61.
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  318. Tam JM, Upadhyay R, Pittet MJ, Weissleder R, Mahmood U. Improved in vivo whole-animal detection limits of green fluorescent protein-expressing tumor lines by spectral fluorescence imaging. Mol Imaging. 2007 Jul-Aug; 6(4):269-76.
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  319. Alencar H, Funovics MA, Figueiredo J, Sawaya H, Weissleder R, Mahmood U. Colonic adenocarcinomas: near-infrared microcatheter imaging of smart probes for early detection--study in mice. Radiology. 2007 Jul; 244(1):232-8.
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  320. Sheth RA, Upadhyay R, Weissleder R, Mahmood U. Real-time multichannel imaging framework for endoscopy, catheters, and fixed geometry intraoperative systems. Mol Imaging. 2007 May-Jun; 6(3):147-55.
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  321. Kock N, Kasmieh R, Weissleder R, Shah K. Tumor therapy mediated by lentiviral expression of shBcl-2 and S-TRAIL. Neoplasia. 2007 May; 9(5):435-42.
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  322. Hilderbrand SA, Weissleder R. Optimized pH-responsive cyanine fluorochromes for detection of acidic environments. Chem Commun (Camb). 2007 Jul 14; (26):2747-9.
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  323. Sosnovik DE, Nahrendorf M, Weissleder R. Molecular magnetic resonance imaging in cardiovascular medicine. Circulation. 2007 Apr 17; 115(15):2076-86.
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  324. Jaffer FA, Kim DE, Quinti L, Tung CH, Aikawa E, Pande AN, Kohler RH, Shi GP, Libby P, Weissleder R. Optical visualization of cathepsin K activity in atherosclerosis with a novel, protease-activatable fluorescence sensor. Circulation. 2007 May 1; 115(17):2292-8.
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  325. McCarthy JR, Kelly KA, Sun EY, Weissleder R. Targeted delivery of multifunctional magnetic nanoparticles. Nanomedicine (Lond). 2007 Apr; 2(2):153-67.
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  326. Ho NH, Weissleder R, Tung CH. A self-immolative reporter for beta-galactosidase sensing. Chembiochem. 2007 Mar 26; 8(5):560-6.
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  327. Nahrendorf M, Sosnovik DE, Waterman P, Swirski FK, Pande AN, Aikawa E, Figueiredo JL, Pittet MJ, Weissleder R. Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct. Circ Res. 2007 Apr 27; 100(8):1218-25.
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  328. Kim Y, Hilderbrand SA, Weissleder R, Tung CH. Sugar sensing based on induced pH changes. Chem Commun (Camb). 2007 Jun 14; (22):2299-301.
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  329. Sosnovik DE, Nahrendorf M, Deliolanis N, Novikov M, Aikawa E, Josephson L, Rosenzweig A, Weissleder R, Ntziachristos V. Fluorescence tomography and magnetic resonance imaging of myocardial macrophage infiltration in infarcted myocardium in vivo. Circulation. 2007 Mar 20; 115(11):1384-91.
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  330. Yuan H, Barnes KR, Weissleder R, Cantley L, Josephson L. Covalent reactions of wortmannin under physiological conditions. Chem Biol. 2007 Mar; 14(3):321-8.
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  331. McCarthy JR, Weissleder R. Model systems for fluorescence and singlet oxygen quenching by metalloporphyrins. ChemMedChem. 2007 Mar; 2(3):360-5.
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  332. Montet X, Figueiredo JL, Alencar H, Ntziachristos V, Mahmood U, Weissleder R. Tomographic fluorescence imaging of tumor vascular volume in mice. Radiology. 2007 Mar; 242(3):751-8.
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  333. Nahrendorf M, Badea C, Hedlund LW, Figueiredo JL, Sosnovik DE, Johnson GA, Weissleder R. High-resolution imaging of murine myocardial infarction with delayed-enhancement cine micro-CT. Am J Physiol Heart Circ Physiol. 2007 Jun; 292(6):H3172-8.
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  334. Ventura A, Kirsch DG, McLaughlin ME, Tuveson DA, Grimm J, Lintault L, Newman J, Reczek EE, Weissleder R, Jacks T. Restoration of p53 function leads to tumour regression in vivo. Nature. 2007 Feb 8; 445(7128):661-5.
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  335. Aikawa E, Nahrendorf M, Sosnovik D, Lok VM, Jaffer FA, Aikawa M, Weissleder R. Multimodality molecular imaging identifies proteolytic and osteogenic activities in early aortic valve disease. Circulation. 2007 Jan 23; 115(3):377-86.
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  336. Swirski FK, Libby P, Aikawa E, Alcaide P, Luscinskas FW, Weissleder R, Pittet MJ. Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata. J Clin Invest. 2007 Jan; 117(1):195-205.
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  337. Izmailova ES, Paz N, Alencar H, Chun M, Schopf L, Hepperle M, Lane JH, Harriman G, Xu Y, Ocain T, Weissleder R, Mahmood U, Healy AM, Jaffee B. Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis. Arthritis Rheum. 2007 Jan; 56(1):117-28.
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  338. Nahrendorf M, Weissleder R. [Advances in cardiovascular medicine through molecular imaging]. Radiologe. 2007 Jan; 47(1):18-24.
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  339. Grimm J, Kircher MF, Weissleder R. [Cell tracking. Principles and applications]. Radiologe. 2007 Jan; 47(1):25-33.
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  340. Montet-Abou K, Montet X, Weissleder R, Josephson L. Cell internalization of magnetic nanoparticles using transfection agents. Mol Imaging. 2007 Jan-Feb; 6(1):1-9.
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  341. Weissleder R, Imhof H. [Molecular imaging--a new emphasis in radiology]. Radiologe. 2007 Jan; 47(1):6-7.
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  342. Nahrendorf M, Weissleder R, Ertl G. Does FXIII deficiency impair wound healing after myocardial infarction? PLoS One. 2006; 1:e48.
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  343. Kelly KA, Allport JR, Yu AM, Sinh S, Sage EH, Gerszten RE, Weissleder R. SPARC is a VCAM-1 counter-ligand that mediates leukocyte transmigration. J Leukoc Biol. 2007 Mar; 81(3):748-56.
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  344. Kelly KA, Waterman P, Weissleder R. In vivo imaging of molecularly targeted phage. Neoplasia. 2006 Dec; 8(12):1011-8.
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  345. Saksena M, Harisinghani M, Hahn P, Kim J, Saokar A, King B, Weissleder R. Comparison of lymphotropic nanoparticle-enhanced MRI sequences in patients with various primary cancers. AJR Am J Roentgenol. 2006 Dec; 187(6):W582-8.
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  346. Kim DE, Tsuji K, Kim YR, Mueller FJ, Eom HS, Snyder EY, Lo EH, Weissleder R, Schellingerhout D. Neural stem cell transplant survival in brains of mice: assessing the effect of immunity and ischemia by using real-time bioluminescent imaging. Radiology. 2006 Dec; 241(3):822-30.
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  347. Sosnovik DE, Weissleder R. Emerging concepts in molecular MRI. Curr Opin Biotechnol. 2007 Feb; 18(1):4-10.
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  348. Campanella GS, Grimm J, Manice LA, Colvin RA, Medoff BD, Wojtkiewicz GR, Weissleder R, Luster AD. Oligomerization of CXCL10 is necessary for endothelial cell presentation and in vivo activity. J Immunol. 2006 Nov 15; 177(10):6991-8.
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  349. Jaffer FA, Sosnovik DE, Nahrendorf M, Weissleder R. Molecular imaging of myocardial infarction. J Mol Cell Cardiol. 2006 Dec; 41(6):921-33.
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  350. Montet X, Funovics M, Montet-Abou K, Weissleder R, Josephson L. Multivalent effects of RGD peptides obtained by nanoparticle display. J Med Chem. 2006 Oct 5; 49(20):6087-93.
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  351. Kozloff KM, Quinti L, Tung C, Weissleder R, Mahmood U. Non-invasive imaging of osteoclast activity via near-infrared cathepsin-K activatable optical probe. J Musculoskelet Neuronal Interact. 2006 Oct-Dec; 6(4):353.
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  352. Funovics MA, Alencar H, Montet X, Weissleder R, Mahmood U. Simultaneous fluorescence imaging of protease expression and vascularity during murine colonoscopy for colonic lesion characterization. Gastrointest Endosc. 2006 Oct; 64(4):589-97.
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  353. Sun EY, Weissleder R, Josephson L. Continuous analyte sensing with magnetic nanoswitches. Small. 2006 Oct; 2(10):1144-7.
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  354. Nahrendorf M, Jaffer FA, Kelly KA, Sosnovik DE, Aikawa E, Libby P, Weissleder R. Noninvasive vascular cell adhesion molecule-1 imaging identifies inflammatory activation of cells in atherosclerosis. Circulation. 2006 Oct 3; 114(14):1504-11.
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  355. Lamfers ML, Fulci G, Gianni D, Tang Y, Kurozumi K, Kaur B, Moeniralm S, Saeki Y, Carette JE, Weissleder R, Vandertop WP, van Beusechem VW, Dirven CM, Chiocca EA. Cyclophosphamide increases transgene expression mediated by an oncolytic adenovirus in glioma-bearing mice monitored by bioluminescence imaging. Mol Ther. 2006 Dec; 14(6):779-88.
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  356. Newton JR, Kelly KA, Mahmood U, Weissleder R, Deutscher SL. In vivo selection of phage for the optical imaging of PC-3 human prostate carcinoma in mice. Neoplasia. 2006 Sep; 8(9):772-80.
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  357. Hynynen K, McDannold N, Vykhodtseva N, Raymond S, Weissleder R, Jolesz FA, Sheikov N. Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery. J Neurosurg. 2006 Sep; 105(3):445-54.
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  358. Fulci G, Breymann L, Gianni D, Kurozomi K, Rhee SS, Yu J, Kaur B, Louis DN, Weissleder R, Caligiuri MA, Chiocca EA. Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses. Proc Natl Acad Sci U S A. 2006 Aug 22; 103(34):12873-8.
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  359. Chen JW, Querol Sans M, Bogdanov A, Weissleder R. Imaging of myeloperoxidase in mice by using novel amplifiable paramagnetic substrates. Radiology. 2006 Aug; 240(2):473-81.
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  360. Law B, Quinti L, Choi Y, Weissleder R, Tung CH. A mitochondrial targeted fusion peptide exhibits remarkable cytotoxicity. Mol Cancer Ther. 2006 Aug; 5(8):1944-9.
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  361. McCarthy JR, Jaffer FA, Weissleder R. A macrophage-targeted theranostic nanoparticle for biomedical applications. Small. 2006 Aug; 2(8-9):983-7.
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  362. Galande AK, Hilderbrand SA, Weissleder R, Tung CH. Enzyme-targeted fluorescent imaging probes on a multiple antigenic peptide core. J Med Chem. 2006 Jul 27; 49(15):4715-20.
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  363. Choi Y, Weissleder R, Tung CH. Selective antitumor effect of novel protease-mediated photodynamic agent. Cancer Res. 2006 Jul 15; 66(14):7225-9.
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  364. Choi Y, Weissleder R, Tung CH. Protease-mediated phototoxicity of a polylysine-chlorin(E6) conjugate. ChemMedChem. 2006 Jul; 1(7):698-701.
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  365. Zacharakis G, Shih H, Ripoll J, Weissleder R, Ntziachristos V. Normalized transillumination of fluorescent proteins in small animals. Mol Imaging. 2006 Jul; 5(3):153-9.
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  366. Kelly KA, Nahrendorf M, Yu AM, Reynolds F, Weissleder R. In vivo phage display selection yields atherosclerotic plaque targeted peptides for imaging. Mol Imaging Biol. 2006 Jul-Aug; 8(4):201-7.
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  367. Mempel TR, Pittet MJ, Khazaie K, Weninger W, Weissleder R, von Boehmer H, von Andrian UH. Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation. Immunity. 2006 Jul; 25(1):129-41.
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  368. Montet X, Weissleder R, Josephson L. Imaging pancreatic cancer with a peptide-nanoparticle conjugate targeted to normal pancreas. Bioconjug Chem. 2006 Jul-Aug; 17(4):905-11.
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  369. Deguchi JO, Aikawa M, Tung CH, Aikawa E, Kim DE, Ntziachristos V, Weissleder R, Libby P. Inflammation in atherosclerosis: visualizing matrix metalloproteinase action in macrophages in vivo. Circulation. 2006 Jul 4; 114(1):55-62.
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  370. Swirski FK, Pittet MJ, Kircher MF, Aikawa E, Jaffer FA, Libby P, Weissleder R. Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease. Proc Natl Acad Sci U S A. 2006 Jul 5; 103(27):10340-5.
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  371. Figueiredo JL, Alencar H, Weissleder R, Mahmood U. Near infrared thoracoscopy of tumoral protease activity for improved detection of peripheral lung cancer. Int J Cancer. 2006 Jun 1; 118(11):2672-7.
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  372. Deramaudt TB, Takaoka M, Upadhyay R, Bowser MJ, Porter J, Lee A, Rhoades B, Johnstone CN, Weissleder R, Hingorani SR, Mahmood U, Rustgi AK. N-cadherin and keratinocyte growth factor receptor mediate the functional interplay between Ki-RASG12V and p53V143A in promoting pancreatic cell migration, invasion, and tissue architecture disruption. Mol Cell Biol. 2006 Jun; 26(11):4185-200.
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  373. Kang HW, Torres D, Wald L, Weissleder R, Bogdanov AA. Targeted imaging of human endothelial-specific marker in a model of adoptive cell transfer. Lab Invest. 2006 Jun; 86(6):599-609.
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  374. Weissleder R. Molecular imaging in cancer. Science. 2006 May 26; 312(5777):1168-71.
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  375. Ji H, Li D, Chen L, Shimamura T, Kobayashi S, McNamara K, Mahmood U, Mitchell A, Sun Y, Al-Hashem R, Chirieac LR, Padera R, Bronson RT, Kim W, Jänne PA, Shapiro GI, Tenen D, Johnson BE, Weissleder R, Sharpless NE, Wong KK. The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies. Cancer Cell. 2006 Jun; 9(6):485-95.
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  376. Kelly KA, Nahrendorf M, Yu AM, Reynolds F, Weissleder R. In Vivo Phage Display Selection Yields Atherosclerotic Plaque Targeted Peptides for Imaging. Mol Imaging Biol. 2006 May 3.
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  377. Montet X, Yuan H, Weissleder R, Josephson L. Enzyme-based visualization of receptor-ligand binding in tissues. Lab Invest. 2006 May; 86(5):517-25.
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  378. Tannous BA, Grimm J, Perry KF, Chen JW, Weissleder R, Breakefield XO. Metabolic biotinylation of cell surface receptors for in vivo imaging. Nat Methods. 2006 May; 3(5):391-6.
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  379. Hsiao JK, Law B, Weissleder R, Tung CH. In-vivo imaging of tumor associated urokinase-type plasminogen activator activity. J Biomed Opt. 2006 May-Jun; 11(3):34013.
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  380. Bardeesy N, Aguirre AJ, Chu GC, Cheng KH, Lopez LV, Hezel AF, Feng B, Brennan C, Weissleder R, Mahmood U, Hanahan D, Redston MS, Chin L, Depinho RA. Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proc Natl Acad Sci U S A. 2006 Apr 11; 103(15):5947-52.
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  381. Jaffer FA, Nahrendorf M, Sosnovik D, Kelly KA, Aikawa E, Weissleder R. Cellular imaging of inflammation in atherosclerosis using magnetofluorescent nanomaterials. Mol Imaging. 2006 Apr-Jun; 5(2):85-92.
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  382. Tréhin R, Figueiredo JL, Pittet MJ, Weissleder R, Josephson L, Mahmood U. Fluorescent nanoparticle uptake for brain tumor visualization. Neoplasia. 2006 Apr; 8(4):302-11.
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  383. Law B, Weissleder R, Tung CH. Peptide-based biomaterials for protease-enhanced drug delivery. Biomacromolecules. 2006 Apr; 7(4):1261-5.
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  384. Sun EY, Josephson L, Weissleder R. "Clickable" nanoparticles for targeted imaging. Mol Imaging. 2006 Apr-Jun; 5(2):122-8.
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  385. Choi Y, McCarthy JR, Weissleder R, Tung CH. Conjugation of a photosensitizer to an oligoarginine-based cell-penetrating peptide increases the efficacy of photodynamic therapy. ChemMedChem. 2006 Apr; 1(4):458-63.
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  386. Yen L, Magnier M, Weissleder R, Stockwell BR, Mulligan RC. Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries. RNA. 2006 May; 12(5):797-806.
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  387. Jaffer FA, Libby P, Weissleder R. Molecular and cellular imaging of atherosclerosis: emerging applications. J Am Coll Cardiol. 2006 Apr 4; 47(7):1328-38.
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  388. Ho NH, Weissleder R, Tung CH. Development of a dual fluorogenic and chromogenic dipeptidyl peptidase IV substrate. Bioorg Med Chem Lett. 2006 May 15; 16(10):2599-602.
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  389. Vianello F, Papeta N, Chen T, Kraft P, White N, Hart WK, Kircher MF, Swart E, Rhee S, Palù G, Irimia D, Toner M, Weissleder R, Poznansky MC. Murine B16 melanomas expressing high levels of the chemokine stromal-derived factor-1/CXCL12 induce tumor-specific T cell chemorepulsion and escape from immune control. J Immunol. 2006 Mar 1; 176(5):2902-14.
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  390. Quinti L, Weissleder R, Tung CH. A fluorescent nanosensor for apoptotic cells. Nano Lett. 2006 Mar; 6(3):488-90.
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  391. Galande AK, Weissleder R, Tung CH. Fluorescence probe with a pH-sensitive trigger. Bioconjug Chem. 2006 Mar-Apr; 17(2):255-7.
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  392. Montet X, Montet-Abou K, Reynolds F, Weissleder R, Josephson L. Nanoparticle imaging of integrins on tumor cells. Neoplasia. 2006 Mar; 8(3):214-22.
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  393. Pande AN, Kohler RH, Aikawa E, Weissleder R, Jaffer FA. Detection of macrophage activity in atherosclerosis in vivo using multichannel, high-resolution laser scanning fluorescence microscopy. J Biomed Opt. 2006 Mar-Apr; 11(2):021009.
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  394. Nahrendorf M, Hu K, Frantz S, Jaffer FA, Tung CH, Hiller KH, Voll S, Nordbeck P, Sosnovik D, Gattenlöhner S, Novikov M, Dickneite G, Reed GL, Jakob P, Rosenzweig A, Bauer WR, Weissleder R, Ertl G. Factor XIII deficiency causes cardiac rupture, impairs wound healing, and aggravates cardiac remodeling in mice with myocardial infarction. Circulation. 2006 Mar 7; 113(9):1196-202.
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  395. Rabin O, Manuel Perez J, Grimm J, Wojtkiewicz G, Weissleder R. An X-ray computed tomography imaging agent based on long-circulating bismuth sulphide nanoparticles. Nat Mater. 2006 Feb; 5(2):118-22.
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  396. Binstadt BA, Patel PR, Alencar H, Nigrovic PA, Lee DM, Mahmood U, Weissleder R, Mathis D, Benoist C. Particularities of the vasculature can promote the organ specificity of autoimmune attack. Nat Immunol. 2006 Mar; 7(3):284-92.
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  397. Yuan H, Luo J, Weissleder R, Cantley L, Josephson L. Wortmannin-C20 conjugates generate wortmannin. J Med Chem. 2006 Jan 26; 49(2):740-7.
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  398. Zhang M, Alicot EM, Chiu I, Li J, Verna N, Vorup-Jensen T, Kessler B, Shimaoka M, Chan R, Friend D, Mahmood U, Weissleder R, Moore FD, Carroll MC. Identification of the target self-antigens in reperfusion injury. J Exp Med. 2006 Jan 23; 203(1):141-52.
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  399. Messerli SM, Prabhakar S, Tang Y, Mahmood U, Giovannini M, Weissleder R, Bronson R, Martuza R, Rabkin S, Breakefield XO. Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2. Hum Gene Ther. 2006 Jan; 17(1):20-30.
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  400. Sun EY, Josephson L, Kelly KA, Weissleder R. Development of nanoparticle libraries for biosensing. Bioconjug Chem. 2006 Jan-Feb; 17(1):109-13.
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  401. Banerjee P, Weissleder R, Bogdanov A. Linear polyethyleneimine grafted to a hyperbranched poly(ethylene glycol)-like core: a copolymer for gene delivery. Bioconjug Chem. 2006 Jan-Feb; 17(1):125-31.
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  402. Pittet MJ, Swirski FK, Reynolds F, Josephson L, Weissleder R. Labeling of immune cells for in vivo imaging using magnetofluorescent nanoparticles. Nat Protoc. 2006; 1(1):73-9.
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  403. Kelly KA, Clemons PA, Yu AM, Weissleder R. High-throughput identification of phage-derived imaging agents. Mol Imaging. 2006 Jan-Mar; 5(1):24-30.
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  404. Montet X, Rajopadhye M, Weissleder R. An albumin-activated far-red fluorochrome for in vivo imaging. ChemMedChem. 2006 Jan; 1(1):66-9.
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  405. Harisinghani MG, Saksena MA, Hahn PF, King B, Kim J, Torabi MT, Weissleder R. Ferumoxtran-10-enhanced MR lymphangiography: does contrast-enhanced imaging alone suffice for accurate lymph node characterization? AJR Am J Roentgenol. 2006 Jan; 186(1):144-8.
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  406. Zacharakis G, Kambara H, Shih H, Ripoll J, Grimm J, Saeki Y, Weissleder R, Ntziachristos V. Volumetric tomography of fluorescent proteins through small animals in vivo. Proc Natl Acad Sci U S A. 2005 Dec 20; 102(51):18252-7.
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  407. McCarthy JR, Perez JM, Brückner C, Weissleder R. Polymeric nanoparticle preparation that eradicates tumors. Nano Lett. 2005 Dec; 5(12):2552-6.
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  408. Brown AB, Mahmood U, Cortes ML, Tang Y, Dai G, Stemmer-Rachamimov A, Prabhakar S, Leishear K, Onda H, Kwiatkowski D, Weissleder R, Breakefield X. Magnetic resonance imaging and characterization of spontaneous lesions in a transgenic mouse model of tuberous sclerosis as a model for endothelial cell-based transgene delivery. Hum Gene Ther. 2005 Dec; 16(12):1367-76.
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  409. Kelloff GJ, Krohn KA, Larson SM, Weissleder R, Mankoff DA, Hoffman JM, Link JM, Guyton KZ, Eckelman WC, Scher HI, O'Shaughnessy J, Cheson BD, Sigman CC, Tatum JL, Mills GQ, Sullivan DC, Woodcock J. The progress and promise of molecular imaging probes in oncologic drug development. Clin Cancer Res. 2005 Nov 15; 11(22):7967-85.
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  410. Shih HA, Harisinghani M, Zietman AL, Wolfgang JA, Saksena M, Weissleder R. Mapping of nodal disease in locally advanced prostate cancer: rethinking the clinical target volume for pelvic nodal irradiation based on vascular rather than bony anatomy. Int J Radiat Oncol Biol Phys. 2005 Nov 15; 63(4):1262-9.
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  411. Alencar H, King R, Funovics M, Stout C, Weissleder R, Mahmood U. A novel mouse model for segmental orthotopic colon cancer. Int J Cancer. 2005 Nov 10; 117(3):335-9.
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  412. Alencar H, Mahmood U, Kawano Y, Hirata T, Weissleder R. Novel multiwavelength microscopic scanner for mouse imaging. Neoplasia. 2005 Nov; 7(11):977-83.
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  413. Querol Sans M, Chen JW, Weissleder R, Bogdanov AA. Myeloperoxidase activity imaging using (67)Ga labeled substrate. Mol Imaging Biol. 2005 Nov-Dec; 7(6):403-10.
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  414. Harisinghani MG, Saksena M, Ross RW, Tabatabaei S, Dahl D, McDougal S, Weissleder R. A pilot study of lymphotrophic nanoparticle-enhanced magnetic resonance imaging technique in early stage testicular cancer: a new method for noninvasive lymph node evaluation. Urology. 2005 Nov; 66(5):1066-71.
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  415. Weissleder R, Kelly K, Sun EY, Shtatland T, Josephson L. Cell-specific targeting of nanoparticles by multivalent attachment of small molecules. Nat Biotechnol. 2005 Nov; 23(11):1418-23.
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  416. Kim YR, Yudina A, Figueiredo J, Reichardt W, Hu-Lowe D, Petrovsky A, Kang HW, Torres D, Mahmood U, Weissleder R, Bogdanov AA. Detection of early antiangiogenic effects in human colon adenocarcinoma xenografts: in vivo changes of tumor blood volume in response to experimental VEGFR tyrosine kinase inhibitor. Cancer Res. 2005 Oct 15; 65(20):9253-60.
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  417. Funovics M, Montet X, Reynolds F, Weissleder R, Josephson L. Nanoparticles for the optical imaging of tumor E-selectin. Neoplasia. 2005 Oct; 7(10):904-11.
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  418. Pivovarov M, Bhandary G, Mahmood U, Zahlmann G, Naraghi M, Weissleder R. MIPortal: a high capacity server for molecular imaging research. Mol Imaging. 2005 Oct-Dec; 4(4):425-31.
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  419. Grimm J, Kirsch DG, Windsor SD, Kim CF, Santiago PM, Ntziachristos V, Jacks T, Weissleder R. Use of gene expression profiling to direct in vivo molecular imaging of lung cancer. Proc Natl Acad Sci U S A. 2005 Oct 4; 102(40):14404-9.
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  420. Tang Y, Kim M, Carrasco D, Kung AL, Chin L, Weissleder R. In vivo assessment of RAS-dependent maintenance of tumor angiogenesis by real-time magnetic resonance imaging. Cancer Res. 2005 Sep 15; 65(18):8324-30.
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  421. Sosnovik DE, Schellenberger EA, Nahrendorf M, Novikov MS, Matsui T, Dai G, Reynolds F, Grazette L, Rosenzweig A, Weissleder R, Josephson L. Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle. Magn Reson Med. 2005 Sep; 54(3):718-24.
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  422. Reichardt W, Hu-Lowe D, Torres D, Weissleder R, Bogdanov A. Imaging of VEGF receptor kinase inhibitor-induced antiangiogenic effects in drug-resistant human adenocarcinoma model. Neoplasia. 2005 Sep; 7(9):847-53.
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  423. Reynolds F, Weissleder R, Josephson L. Protamine as an efficient membrane-translocating peptide. Bioconjug Chem. 2005 Sep-Oct; 16(5):1240-5.
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  424. Hilderbrand SA, Kelly KA, Weissleder R, Tung CH. Monofunctional near-infrared fluorochromes for imaging applications. Bioconjug Chem. 2005 Sep-Oct; 16(5):1275-81.
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  425. Turvey SE, Swart E, Denis MC, Mahmood U, Benoist C, Weissleder R, Mathis D. Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes. J Clin Invest. 2005 Sep; 115(9):2454-61.
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  426. Law B, Weissleder R, Tung CH. Mechanism-based fluorescent reporter for protein kinase A detection. Chembiochem. 2005 Aug; 6(8):1361-7.
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  427. Montet X, Ntziachristos V, Grimm J, Weissleder R. Tomographic fluorescence mapping of tumor targets. Cancer Res. 2005 Jul 15; 65(14):6330-6.
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  428. Zacharakis G, Ripoll J, Weissleder R, Ntziachristos V. Fluorescent protein tomography scanner for small animal imaging. IEEE Trans Med Imaging. 2005 Jul; 24(7):878-85.
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  429. Montet-Abou K, Montet X, Weissleder R, Josephson L. Transfection agent induced nanoparticle cell loading. Mol Imaging. 2005 Jul-Sep; 4(3):165-71.
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  430. Graves EE, Yessayan D, Turner G, Weissleder R, Ntziachristos V. Validation of in vivo fluorochrome concentrations measured using fluorescence molecular tomography. J Biomed Opt. 2005 Jul-Aug; 10(4):44019.
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  431. Shah K, Tung CH, Breakefield XO, Weissleder R. In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis. Mol Ther. 2005 Jun; 11(6):926-31.
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  432. Bremer C, Ntziachristos V, Weitkamp B, Theilmeier G, Heindel W, Weissleder R. Optical imaging of spontaneous breast tumors using protease sensing 'smart' optical probes. Invest Radiol. 2005 Jun; 40(6):321-7.
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  433. Tsourkas A, Newton G, Perez JM, Basilion JP, Weissleder R. Detection of peroxidase/H2O2-mediated oxidation with enhanced yellow fluorescent protein. Anal Chem. 2005 May 1; 77(9):2862-7.
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  434. Yuan H, Luo J, Field S, Weissleder R, Cantley L, Josephson L. Synthesis and activity of C11-modified wortmannin probes for PI3 kinase. Bioconjug Chem. 2005 May-Jun; 16(3):669-75.
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  435. Tsourkas A, Shinde-Patil VR, Kelly KA, Patel P, Wolley A, Allport JR, Weissleder R. In vivo imaging of activated endothelium using an anti-VCAM-1 magnetooptical probe. Bioconjug Chem. 2005 May-Jun; 16(3):576-81.
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  436. Querol M, Chen JW, Weissleder R, Bogdanov A. DTPA-bisamide-based MR sensor agents for peroxidase imaging. Org Lett. 2005 Apr 28; 7(9):1719-22.
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  437. Chen J, Tung CH, Allport JR, Chen S, Weissleder R, Huang PL. Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction. Circulation. 2005 Apr 12; 111(14):1800-5.
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  438. Shah K, Weissleder R. Molecular optical imaging: applications leading to the development of present day therapeutics. NeuroRx. 2005 Apr; 2(2):215-25.
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  439. Gillies RJ, Hoffman JM, Lam KS, Menkens AE, Piwnica-Worms DR, Sullivan DC, Weissleder R. Meeting report: high-throughput technologies for in vivo imaging agents. Mol Imaging. 2005 Apr-Jun; 4(2):98-103.
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  440. Tannous BA, Kim DE, Fernandez JL, Weissleder R, Breakefield XO. Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. Mol Ther. 2005 Mar; 11(3):435-43.
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  441. Galande AK, Weissleder R, Tung CH. An effective method of on-resin disulfide bond formation in peptides. J Comb Chem. 2005 Mar-Apr; 7(2):174-7.
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  442. Shinde Patil VR, Friedrich EB, Wolley AE, Gerszten RE, Allport JR, Weissleder R. Bone marrow-derived lin(-)c-kit(+)Sca-1+ stem cells do not contribute to vasculogenesis in Lewis lung carcinoma. Neoplasia. 2005 Mar; 7(3):234-40.
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  443. Law B, Hsiao JK, Bugge TH, Weissleder R, Tung CH. Optical zymography for specific detection of urokinase plasminogen activator activity in biological samples. Anal Biochem. 2005 Mar 1; 338(1):151-8.
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  444. Ntziachristos V, Ripoll J, Wang LV, Weissleder R. Looking and listening to light: the evolution of whole-body photonic imaging. Nat Biotechnol. 2005 Mar; 23(3):313-20.
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  445. Jaffer FA, Weissleder R. Molecular imaging in the clinical arena. JAMA. 2005 Feb 16; 293(7):855-62.
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  446. Koch AM, Reynolds F, Merkle HP, Weissleder R, Josephson L. Transport of surface-modified nanoparticles through cell monolayers. Chembiochem. 2005 Feb; 6(2):337-45.
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  447. Kim DE, Schellingerhout D, Jaffer FA, Weissleder R, Tung CH. Near-infrared fluorescent imaging of cerebral thrombi and blood-brain barrier disruption in a mouse model of cerebral venous sinus thrombosis. J Cereb Blood Flow Metab. 2005 Feb; 25(2):226-33.
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  448. Reynolds F, O'loughlin T, Weissleder R, Josephson L. Method of determining nanoparticle core weight. Anal Chem. 2005 Feb 1; 77(3):814-7.
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  449. Chen WT, Mahmood U, Weissleder R, Tung CH. Arthritis imaging using a near-infrared fluorescence folate-targeted probe. Arthritis Res Ther. 2005; 7(2):R310-7.
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  450. Kelly KA, Allport JR, Tsourkas A, Shinde-Patil VR, Josephson L, Weissleder R. Detection of vascular adhesion molecule-1 expression using a novel multimodal nanoparticle. Circ Res. 2005 Feb 18; 96(3):327-36.
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  451. Bogdanov AA, Chen JW, Kang HW, Weissleder R. Magnetic resonance signal amplification probes. Ernst Schering Res Found Workshop. 2005; (49):147-57.
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  452. Tung CH, Quinti L, Jaffer FA, Weissleder R. A branched fluorescent peptide probe for imaging of activated platelets. Mol Pharm. 2005 Jan-Feb; 2(1):92-5.
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  453. Kim CF, Jackson EL, Kirsch DG, Grimm J, Shaw AT, Lane K, Kissil J, Olive KP, Sweet-Cordero A, Weissleder R, Jacks T. Mouse models of human non-small-cell lung cancer: raising the bar. Cold Spring Harb Symp Quant Biol. 2005; 70:241-50.
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  454. Choi HK, Yessayan D, Choi HJ, Schellenberger E, Bogdanov A, Josephson L, Weissleder R, Ntziachristos V. Quantitative analysis of chemotherapeutic effects in tumors using in vivo staining and correlative histology. Cell Oncol. 2005; 27(3):183-90.
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  455. Shah K, Bureau E, Kim DE, Yang K, Tang Y, Weissleder R, Breakefield XO. Glioma therapy and real-time imaging of neural precursor cell migration and tumor regression. Ann Neurol. 2005 Jan; 57(1):34-41.
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  456. Wunder A, Schellenberger E, Mahmood U, Bogdanov A, Müller-Ladner U, Weissleder R, Josephson L. Methotrexate-induced accumulation of fluorescent annexin V in collagen-induced arthritis. Mol Imaging. 2005 Jan-Mar; 4(1):1-6.
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  457. Chen WT, Khazaie K, Zhang G, Weissleder R, Tung CH. Detection of dysplastic intestinal adenomas using a fluorescent folate imaging probe. Mol Imaging. 2005 Jan-Mar; 4(1):67-74.
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  458. Sosnovik D, Weissleder R. Magnetic resonance and fluorescence based molecular imaging technologies. Prog Drug Res. 2005; 62:83-115.
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  459. Harisinghani MG, Weissleder R. Sensitive, noninvasive detection of lymph node metastases. PLoS Med. 2004 Dec; 1(3):e66.
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  460. Chen ML, Pittet MJ, Gorelik L, Flavell RA, Weissleder R, von Boehmer H, Khazaie K. Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo. Proc Natl Acad Sci U S A. 2005 Jan 11; 102(2):419-24.
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  461. Metelev V, Weissleder R, Bogdanov A. Synthesis and properties of fluorescent NF-kappa B-recognizing hairpin oligodeoxyribonucleotide decoys. Bioconjug Chem. 2004 Nov-Dec; 15(6):1481-7.
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  462. Pham W, Choi Y, Weissleder R, Tung CH. Developing a peptide-based near-infrared molecular probe for protease sensing. Bioconjug Chem. 2004 Nov-Dec; 15(6):1403-7.
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  463. Chen JW, Pham W, Weissleder R, Bogdanov A. Human myeloperoxidase: a potential target for molecular MR imaging in atherosclerosis. Magn Reson Med. 2004 Nov; 52(5):1021-8.
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  464. Allport JR, Shinde Patil VR, Weissleder R. Murine neuronal progenitor cells are preferentially recruited to tumor vasculature via alpha4-integrin and SDF-1alpha-dependent mechanisms. Cancer Biol Ther. 2004 Sep; 3(9):838-44.
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  465. Kelly K, Alencar H, Funovics M, Mahmood U, Weissleder R. Detection of invasive colon cancer using a novel, targeted, library-derived fluorescent peptide. Cancer Res. 2004 Sep 1; 64(17):6247-51.
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  466. Kim YR, Savellano MD, Savellano DH, Weissleder R, Bogdanov A. Measurement of tumor interstitial volume fraction: method and implication for drug delivery. Magn Reson Med. 2004 Sep; 52(3):485-94.
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  467. Banerjee P, Reichardt W, Weissleder R, Bogdanov A. Novel hyperbranched dendron for gene transfer in vitro and in vivo. Bioconjug Chem. 2004 Sep-Oct; 15(5):960-8.
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  468. Schellenberger EA, Sosnovik D, Weissleder R, Josephson L. Magneto/optical annexin V, a multimodal protein. Bioconjug Chem. 2004 Sep-Oct; 15(5):1062-7.
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  469. Ntziachristos V, Schellenberger EA, Ripoll J, Yessayan D, Graves E, Bogdanov A, Josephson L, Weissleder R. Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate. Proc Natl Acad Sci U S A. 2004 Aug 17; 101(33):12294-9.
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  470. Denis MC, Mahmood U, Benoist C, Mathis D, Weissleder R. Imaging inflammation of the pancreatic islets in type 1 diabetes. Proc Natl Acad Sci U S A. 2004 Aug 24; 101(34):12634-9.
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  471. Pham W, Kircher MF, Weissleder R, Tung CH. Enhancing membrane permeability by fatty acylation of oligoarginine peptides. Chembiochem. 2004 Aug 6; 5(8):1148-51.
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  472. Shah K, Jacobs A, Breakefield XO, Weissleder R. Molecular imaging of gene therapy for cancer. Gene Ther. 2004 Aug; 11(15):1175-87.
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  473. Wunder A, Tung CH, Müller-Ladner U, Weissleder R, Mahmood U. In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response. Arthritis Rheum. 2004 Aug; 50(8):2459-65.
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  474. Kelly KA, Reynolds F, Weissleder R, Josephson L. Fluorescein isothiocyanate-hapten immunoassay for determination of peptide-cell interactions. Anal Biochem. 2004 Jul 15; 330(2):181-5.
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  475. Chen WT, Tung CH, Weissleder R. Imaging reactive oxygen species in arthritis. Mol Imaging. 2004 Jul; 3(3):159-62.
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  476. Jaffer FA, Tung CH, Wykrzykowska JJ, Ho NH, Houng AK, Reed GL, Weissleder R. Molecular imaging of factor XIIIa activity in thrombosis using a novel, near-infrared fluorescent contrast agent that covalently links to thrombi. Circulation. 2004 Jul 13; 110(2):170-6.
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  477. Gondi CS, Lakka SS, Yanamandra N, Olivero WC, Dinh DH, Gujrati M, Tung CH, Weissleder R, Rao JS. Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas. Cancer Res. 2004 Jun 15; 64(12):4069-77.
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  478. Graves EE, Weissleder R, Ntziachristos V. Fluorescence molecular imaging of small animal tumor models. Curr Mol Med. 2004 Jun; 4(4):419-30.
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  479. Funovics MA, Weissleder R, Mahmood U. Catheter-based in vivo imaging of enzyme activity and gene expression: feasibility study in mice. Radiology. 2004 Jun; 231(3):659-66.
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  480. Tsourkas A, Weissleder R. Illuminating the dynamics of intracellular activity with 'active' molecular reporters. Mech Chem Biosyst. 2004 Jun; 1(2):133-45.
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  481. Shah K, Tung CH, Yang K, Weissleder R, Breakefield XO. Inducible release of TRAIL fusion proteins from a proapoptotic form for tumor therapy. Cancer Res. 2004 May 1; 64(9):3236-42.
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  482. Tsourkas A, Hofstetter O, Hofstetter H, Weissleder R, Josephson L. Magnetic relaxation switch immunosensors detect enantiomeric impurities. Angew Chem Int Ed Engl. 2004 Apr 26; 43(18):2395-9.
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  483. Schellenberger EA, Reynolds F, Weissleder R, Josephson L. Surface-functionalized nanoparticle library yields probes for apoptotic cells. Chembiochem. 2004 Mar 5; 5(3):275-9.
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  484. Perez JM, Josephson L, Weissleder R. Use of magnetic nanoparticles as nanosensors to probe for molecular interactions. Chembiochem. 2004 Mar 5; 5(3):261-4.
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  485. Schellenberger EA, Weissleder R, Josephson L. Optimal modification of annexin V with fluorescent dyes. Chembiochem. 2004 Mar 5; 5(3):271-4.
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  486. Jaffer FA, Weissleder R. Seeing within: molecular imaging of the cardiovascular system. Circ Res. 2004 Mar 5; 94(4):433-45.
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  487. Messerli SM, Prabhakar S, Tang Y, Shah K, Cortes ML, Murthy V, Weissleder R, Breakefield XO, Tung CH. A novel method for imaging apoptosis using a caspase-1 near-infrared fluorescent probe. Neoplasia. 2004 Mar-Apr; 6(2):95-105.
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  488. Kircher MF, Weissleder R, Josephson L. A dual fluorochrome probe for imaging proteases. Bioconjug Chem. 2004 Mar-Apr; 15(2):242-8.
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  489. Tung CH, Zeng Q, Shah K, Kim DE, Schellingerhout D, Weissleder R. In vivo imaging of beta-galactosidase activity using far red fluorescent switch. Cancer Res. 2004 Mar 1; 64(5):1579-83.
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  490. Kim DE, Schellingerhout D, Ishii K, Shah K, Weissleder R. Imaging of stem cell recruitment to ischemic infarcts in a murine model. Stroke. 2004 Apr; 35(4):952-7.
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  491. Graves EE, Culver JP, Ripoll J, Weissleder R, Ntziachristos V. Singular-value analysis and optimization of experimental parameters in fluorescence molecular tomography. J Opt Soc Am A Opt Image Sci Vis. 2004 Feb; 21(2):231-41.
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  492. Grimm J, Perez JM, Josephson L, Weissleder R. Novel nanosensors for rapid analysis of telomerase activity. Cancer Res. 2004 Jan 15; 64(2):639-43.
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  493. Shah K, Tung CH, Chang CH, Slootweg E, O'Loughlin T, Breakefield XO, Weissleder R. In vivo imaging of HIV protease activity in amplicon vector-transduced gliomas. Cancer Res. 2004 Jan 1; 64(1):273-8.
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  494. Zhao M, Weissleder R. Intracellular cargo delivery using tat peptide and derivatives. Med Res Rev. 2004 Jan; 24(1):1-12.
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  495. Law B, Curino A, Bugge TH, Weissleder R, Tung CH. Design, synthesis, and characterization of urokinase plasminogen-activator-sensitive near-infrared reporter. Chem Biol. 2004 Jan; 11(1):99-106.
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  496. Kircher MF, Mahmood U, King RS, Weissleder R, Josephson L. A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor delineation. Cancer Res. 2003 Dec 1; 63(23):8122-5.
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  497. Simonova M, Shtanko O, Sergeyev N, Weissleder R, Bogdanov A. Engineering of technetium-99m-binding artificial receptors for imaging gene expression. J Gene Med. 2003 Dec; 5(12):1056-66.
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  498. Högemann-Savellano D, Bos E, Blondet C, Sato F, Abe T, Josephson L, Weissleder R, Gaudet J, Sgroi D, Peters PJ, Basilion JP. The transferrin receptor: a potential molecular imaging marker for human cancer. Neoplasia. 2003 Nov-Dec; 5(6):495-506.
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  499. Koch AM, Reynolds F, Kircher MF, Merkle HP, Weissleder R, Josephson L. Uptake and metabolism of a dual fluorochrome Tat-nanoparticle in HeLa cells. Bioconjug Chem. 2003 Nov-Dec; 14(6):1115-21.
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  500. Kircher MF, Allport JR, Graves EE, Love V, Josephson L, Lichtman AH, Weissleder R. In vivo high resolution three-dimensional imaging of antigen-specific cytotoxic T-lymphocyte trafficking to tumors. Cancer Res. 2003 Oct 15; 63(20):6838-46.
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  501. Shah K, Tang Y, Breakefield X, Weissleder R. Real-time imaging of TRAIL-induced apoptosis of glioma tumors in vivo. Oncogene. 2003 Oct 9; 22(44):6865-72.
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  502. Funovics MA, Alencar H, Su HS, Khazaie K, Weissleder R, Mahmood U. Miniaturized multichannel near infrared endoscope for mouse imaging. Mol Imaging. 2003 Oct; 2(4):350-7.
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  503. Moffat BA, Reddy GR, McConville P, Hall DE, Chenevert TL, Kopelman RR, Philbert M, Weissleder R, Rehemtulla A, Ross BD. A novel polyacrylamide magnetic nanoparticle contrast agent for molecular imaging using MRI. Mol Imaging. 2003 Oct; 2(4):324-32.
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  504. Tung CH, Ho NH, Zeng Q, Tang Y, Jaffer FA, Reed GL, Weissleder R. Novel factor XIII probes for blood coagulation imaging. Chembiochem. 2003 Sep 5; 4(9):897-9.
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  505. Funovics M, Weissleder R, Tung CH. Protease sensors for bioimaging. Anal Bioanal Chem. 2003 Nov; 377(6):956-63.
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  506. Pham W, Lai WF, Weissleder R, Tung CH. High efficiency synthesis of a bioconjugatable near-infrared fluorochrome. Bioconjug Chem. 2003 Sep-Oct; 14(5):1048-51.
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  507. Tang Y, Shah K, Messerli SM, Snyder E, Breakefield X, Weissleder R. In vivo tracking of neural progenitor cell migration to glioblastomas. Hum Gene Ther. 2003 Sep 1; 14(13):1247-54.
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  508. Perez JM, Simeone FJ, Saeki Y, Josephson L, Weissleder R. Viral-induced self-assembly of magnetic nanoparticles allows the detection of viral particles in biological media. J Am Chem Soc. 2003 Aug 27; 125(34):10192-3.
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  509. Harisinghani MG, Barentsz J, Hahn PF, Deserno WM, Tabatabaei S, van de Kaa CH, de la Rosette J, Weissleder R. Noninvasive detection of clinically occult lymph-node metastases in prostate cancer. N Engl J Med. 2003 Jun 19; 348(25):2491-9.
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  510. Graves EE, Ripoll J, Weissleder R, Ntziachristos V. A submillimeter resolution fluorescence molecular imaging system for small animal imaging. Med Phys. 2003 May; 30(5):901-11.
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  511. Mahmood U, Weissleder R. Near-infrared optical imaging of proteases in cancer. Mol Cancer Ther. 2003 May; 2(5):489-96.
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  512. Moon WK, Lin Y, O'Loughlin T, Tang Y, Kim DE, Weissleder R, Tung CH. Enhanced tumor detection using a folate receptor-targeted near-infrared fluorochrome conjugate. Bioconjug Chem. 2003 May-Jun; 14(3):539-45.
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  513. Yip S, Aboody KS, Burns M, Imitola J, Boockvar JA, Allport J, Park KI, Teng YD, Lachyankar M, McIntosh T, O'Rourke DM, Khoury S, Weissleder R, Black PM, Weiss W, Snyder EY. Neural stem cell biology may be well suited for improving brain tumor therapies. Cancer J. 2003 May-Jun; 9(3):189-204.
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  514. Schellenberger EA, Bogdanov A, Petrovsky A, Ntziachristos V, Weissleder R, Josephson L. Optical imaging of apoptosis as a biomarker of tumor response to chemotherapy. Neoplasia. 2003 May-Jun; 5(3):187-92.
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  515. Allport JR, Weissleder R. Murine Lewis lung carcinoma-derived endothelium expresses markers of endothelial activation and requires tumor-specific extracellular matrix in vitro. Neoplasia. 2003 May-Jun; 5(3):205-17.
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  516. Petrovsky A, Schellenberger E, Josephson L, Weissleder R, Bogdanov A. Near-infrared fluorescent imaging of tumor apoptosis. Cancer Res. 2003 Apr 15; 63(8):1936-42.
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  517. Lin Y, Weissleder R, Tung CH. Synthesis and properties of sulfhydryl-reactive near-infrared cyanine fluorochromes for fluorescence imaging. Mol Imaging. 2003 Apr; 2(2):87-92.
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  518. Zhao M, Josephson L, Tang Y, Weissleder R. Magnetic sensors for protease assays. Angew Chem Int Ed Engl. 2003 Mar 28; 42(12):1375-8.
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  519. Tung CH, Weissleder R. Arginine containing peptides as delivery vectors. Adv Drug Deliv Rev. 2003 Feb 10; 55(2):281-94.
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  520. Rudin M, Weissleder R. Molecular imaging in drug discovery and development. Nat Rev Drug Discov. 2003 Feb; 2(2):123-31.
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  521. Weissleder R, Ntziachristos V. Shedding light onto live molecular targets. Nat Med. 2003 Jan; 9(1):123-8.
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  522. Josephson L, Mahmood U, Wunderbaldinger P, Tang Y, Weissleder R. Pan and sentinel lymph node visualization using a near-infrared fluorescent probe. Mol Imaging. 2003 Jan; 2(1):18-23.
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  523. Bremer C, Mustafa M, Bogdanov A, Ntziachristos V, Petrovsky A, Weissleder R. Steady-state blood volume measurements in experimental tumors with different angiogenic burdens a study in mice. Radiology. 2003 Jan; 226(1):214-20.
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  524. Kim YR, Savellano MD, Weissleder R, Bogdanov A. Steady-state and dynamic contrast MR imaging of human prostate cancer xenograft tumors: a comparative study. Technol Cancer Res Treat. 2002 Dec; 1(6):489-95.
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  525. Ichikawa T, Högemann D, Saeki Y, Tyminski E, Terada K, Weissleder R, Chiocca EA, Basilion JP. MRI of transgene expression: correlation to therapeutic gene expression. Neoplasia. 2002 Nov-Dec; 4(6):523-30.
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  526. Tung CH, Mueller S, Weissleder R. Novel branching membrane translocational peptide as gene delivery vector. Bioorg Med Chem. 2002 Nov; 10(11):3609-14.
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  527. Messerli SM, Tang Y, Giovannini M, Bronson R, Weissleder R, Breakefield XO. Detection of spontaneous schwannomas by MRI in a transgenic murine model of neurofibromatosis type 2. Neoplasia. 2002 Nov-Dec; 4(6):501-9.
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  528. Jaffer FA, Tung CH, Gerszten RE, Weissleder R. In vivo imaging of thrombin activity in experimental thrombi with thrombin-sensitive near-infrared molecular probe. Arterioscler Thromb Vasc Biol. 2002 Nov 1; 22(11):1929-35.
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  529. Pham W, Weissleder R, Tung CH. An azulene dimer as a near-infrared quencher. Angew Chem Int Ed Engl. 2002 Oct 4; 41(19):3659-62, 3519.
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  530. Schellingerhout D, Accorsi R, Mahmood U, Idoine J, Lanza RC, Weissleder R. Coded aperture nuclear scintigraphy: a novel small animal imaging technique. Mol Imaging. 2002 Oct; 1(4):344-53.
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  531. Ntziachristos V, Ripoll J, Weissleder R. Would near-infrared fluorescence signals propagate through large human organs for clinical studies? Errata. Opt Lett. 2002 Sep 15; 27(18):1652.
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  532. Bremer C, Ntziachristos V, Weissleder R. Optical-based molecular imaging: contrast agents and potential medical applications. Eur Radiol. 2003 Feb; 13(2):231-43.
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  533. Tung CH, Lin Y, Moon WK, Weissleder R. A receptor-targeted near-infrared fluorescence probe for in vivo tumor imaging. Chembiochem. 2002 Aug 2; 3(8):784-6.
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  534. Ntziachristos V, Bremer C, Tung C, Weissleder R. Imaging cathepsin B up-regulation in HT-1080 tumor models using fluorescence-mediated molecular tomography (FMT). Acad Radiol. 2002 Aug; 9 Suppl 2:S323-5.
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  535. Bremer C, Tung CH, Weissleder R. Molecular imaging of MMP expression and therapeutic MMP inhibition. Acad Radiol. 2002 Aug; 9 Suppl 2:S314-5.
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  536. Mahmood U, Tung CH, Tang Y, Weissleder R. Feasibility of in vivo multichannel optical imaging of gene expression: experimental study in mice. Radiology. 2002 Aug; 224(2):446-51.
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  537. Wunderbaldinger P, Josephson L, Weissleder R. Crosslinked iron oxides (CLIO): a new platform for the development of targeted MR contrast agents. Acad Radiol. 2002 Aug; 9 Suppl 2:S304-6.
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  538. Schellenberger EA, Högemann D, Josephson L, Weissleder R. Annexin V-CLIO: a nanoparticle for detecting apoptosis by MRI. Acad Radiol. 2002 Aug; 9 Suppl 2:S310-1.
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  539. Harisinghani MG, Barentsz JO, Hahn PF, Deserno W, de la Rosette J, Saini S, Marten K, Weissleder R. MR lymphangiography for detection of minimal nodal disease in patients with prostate cancer. Acad Radiol. 2002 Aug; 9 Suppl 2:S312-3.
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  540. Perez JM, Josephson L, O'Loughlin T, Högemann D, Weissleder R. Magnetic relaxation switches capable of sensing molecular interactions. Nat Biotechnol. 2002 Aug; 20(8):816-20.
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  541. Ntziachristos V, Bremer C, Weissleder R. Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging. Eur Radiol. 2003 Jan; 13(1):195-208.
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  542. Zhao M, Kircher MF, Josephson L, Weissleder R. Differential conjugation of tat peptide to superparamagnetic nanoparticles and its effect on cellular uptake. Bioconjug Chem. 2002 Jul-Aug; 13(4):840-4.
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  543. Ntziachristos V, Tung CH, Bremer C, Weissleder R. Fluorescence molecular tomography resolves protease activity in vivo. Nat Med. 2002 Jul; 8(7):757-60.
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  544. Chen J, Tung CH, Mahmood U, Ntziachristos V, Gyurko R, Fishman MC, Huang PL, Weissleder R. In vivo imaging of proteolytic activity in atherosclerosis. Circulation. 2002 Jun 11; 105(23):2766-71.
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  545. Mahmood U, Weissleder R. Some tools for molecular imaging. Acad Radiol. 2002 Jun; 9(6):629-31.
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  546. Ntziachristos V, Weissleder R. Charge-coupled-device based scanner for tomography of fluorescent near-infrared probes in turbid media. Med Phys. 2002 May; 29(5):803-9.
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  547. Bogdanov AA, Lin CP, Simonova M, Matuszewski L, Weissleder R. Cellular activation of the self-quenched fluorescent reporter probe in tumor microenvironment. Neoplasia. 2002 May-Jun; 4(3):228-36.
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  548. Josephson L, Kircher MF, Mahmood U, Tang Y, Weissleder R. Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes. Bioconjug Chem. 2002 May-Jun; 13(3):554-60.
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  549. Lin Y, Weissleder R, Tung CH. Novel near-infrared cyanine fluorochromes: synthesis, properties, and bioconjugation. Bioconjug Chem. 2002 May-Jun; 13(3):605-10.
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  550. Ripoll J, Nieto-Vesperinas M, Weissleder R, Ntziachristos V. Fast analytical approximation for arbitrary geometries in diffuse optical tomography. Opt Lett. 2002 Apr 1; 27(7):527-9.
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  551. Bachoo RM, Maher EA, Ligon KL, Sharpless NE, Chan SS, You MJ, Tang Y, DeFrances J, Stover E, Weissleder R, Rowitch DH, Louis DN, DePinho RA. Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell. 2002 Apr; 1(3):269-77.
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  552. Kircher MF, Josephson L, Weissleder R. Ratio imaging of enzyme activity using dual wavelength optical reporters. Mol Imaging. 2002 Apr-Jun; 1(2):89-95.
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  553. Moore A, Sun PZ, Cory D, Högemann D, Weissleder R, Lipes MA. MRI of insulitis in autoimmune diabetes. Magn Reson Med. 2002 Apr; 47(4):751-8.
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  554. Ntziachristos V, Bremer C, Graves EE, Ripoll J, Weissleder R. In vivo tomographic imaging of near-infrared fluorescent probes. Mol Imaging. 2002 Apr-Jun; 1(2):82-8.
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  555. Schellenberger EA, Bogdanov A, Högemann D, Tait J, Weissleder R, Josephson L. Annexin V-CLIO: a nanoparticle for detecting apoptosis by MRI. Mol Imaging. 2002 Apr-Jun; 1(2):102-7.
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  556. Perez JM, O'Loughin T, Simeone FJ, Weissleder R, Josephson L. DNA-based magnetic nanoparticle assembly acts as a magnetic relaxation nanoswitch allowing screening of DNA-cleaving agents. J Am Chem Soc. 2002 Mar 27; 124(12):2856-7.
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  557. Wunderbaldinger P, Josephson L, Weissleder R. Tat peptide directs enhanced clearance and hepatic permeability of magnetic nanoparticles. Bioconjug Chem. 2002 Mar-Apr; 13(2):264-8.
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  558. Bremer C, Tung CH, Bogdanov A, Weissleder R. Imaging of differential protease expression in breast cancers for detection of aggressive tumor phenotypes. Radiology. 2002 Mar; 222(3):814-8.
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  559. Ntziachristos V, Ripoll J, Weissleder R. Would near-infrared fluorescence signals propagate through large human organs for clinical studies? Opt Lett. 2002 Mar 1; 27(5):333-5.
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  560. Tung CH, Gerszten RE, Jaffer FA, Weissleder R. A novel near-infrared fluorescence sensor for detection of thrombin activation in blood. Chembiochem. 2002 Mar 1; 3(2-3):207-11.
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  561. Wunderbaldinger P, Josephson L, Bremer C, Moore A, Weissleder R. Detection of lymph node metastases by contrast-enhanced MRI in an experimental model. Magn Reson Med. 2002 Feb; 47(2):292-7.
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  562. Ji H, Ohmura K, Mahmood U, Lee DM, Hofhuis FM, Boackle SA, Takahashi K, Holers VM, Walport M, Gerard C, Ezekowitz A, Carroll MC, Brenner M, Weissleder R, Verbeek JS, Duchatelle V, Degott C, Benoist C, Mathis D. Arthritis critically dependent on innate immune system players. Immunity. 2002 Feb; 16(2):157-68.
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  563. Marten K, Bremer C, Khazaie K, Sameni M, Sloane B, Tung CH, Weissleder R. Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice. Gastroenterology. 2002 Feb; 122(2):406-14.
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  564. Melder RJ, Munn LL, Stoll BR, Marecos EM, Baxter LT, Weissleder R, Jain RK. Systemic distribution and tumor localization of adoptively transferred lymphocytes in mice: comparison with physiologically based pharmacokinetic model. Neoplasia. 2002 Jan-Feb; 4(1):3-8.
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  565. Högemann D, Ntziachristos V, Josephson L, Weissleder R. High throughput magnetic resonance imaging for evaluating targeted nanoparticle probes. Bioconjug Chem. 2002 Jan-Feb; 13(1):116-21.
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  566. Kang HW, Josephson L, Petrovsky A, Weissleder R, Bogdanov A. Magnetic resonance imaging of inducible E-selectin expression in human endothelial cell culture. Bioconjug Chem. 2002 Jan-Feb; 13(1):122-7.
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  567. Weissleder R. Scaling down imaging: molecular mapping of cancer in mice. Nat Rev Cancer. 2002 Jan; 2(1):11-8.
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  568. Kang HW, Weissleder R, Bogdanov A. Targeting of MPEG-protected polyamino acid carrier to human E-selectin in vitro. Amino Acids. 2002; 23(1-3):301-8.
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  569. Bogdanov A, Matuszewski L, Bremer C, Petrovsky A, Weissleder R. Oligomerization of paramagnetic substrates result in signal amplification and can be used for MR imaging of molecular targets. Mol Imaging. 2002 Jan-Mar; 1(1):16-23.
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  570. Allport JR, Weissleder R. In vivo imaging of gene and cell therapies. Exp Hematol. 2001 Nov; 29(11):1237-46.
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  571. Bremer C, Bredow S, Mahmood U, Weissleder R, Tung CH. Optical imaging of matrix metalloproteinase-2 activity in tumors: feasibility study in a mouse model. Radiology. 2001 Nov; 221(2):523-9.
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  572. Moore A, Josephson L, Bhorade RM, Basilion JP, Weissleder R. Human transferrin receptor gene as a marker gene for MR imaging. Radiology. 2001 Oct; 221(1):244-50.
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  573. Moore A, Bonner-Weir S, Weissleder R. Noninvasive in vivo measurement of beta-cell mass in mouse model of diabetes. Diabetes. 2001 Oct; 50(10):2231-6.
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  574. Dodd CH, Hsu HC, Chu WJ, Yang P, Zhang HG, Mountz JD, Zinn K, Forder J, Josephson L, Weissleder R, Mountz JM, Mountz JD. Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles. J Immunol Methods. 2001 Oct 1; 256(1-2):89-105.
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  575. Harisinghani MG, Jhaveri KS, Weissleder R, Schima W, Saini S, Hahn PF, Mueller PR. MRI contrast agents for evaluating focal hepatic lesions. Clin Radiol. 2001 Sep; 56(9):714-25.
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  576. O'Neill MJ, Weissleder R, Gervais DA, Hahn PF, Mueller PR. Tunneled peritoneal catheter placement under sonographic and fluoroscopic guidance in the palliative treatment of malignant ascites. AJR Am J Roentgenol. 2001 Sep; 177(3):615-8.
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  577. Harisinghani MG, Saini S, Weissleder R, Rubin D, deLange E, Harms S, Weinreb J, Small W, Sukerkar A, Brown JJ, Zelch J, Lucas M, Morris M, Hahn PF. Splenic imaging with ultrasmall superparamagnetic iron oxide ferumoxtran-10 (AMI-7227): preliminary observations. J Comput Assist Tomogr. 2001 Sep-Oct; 25(5):770-6.
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  578. Spear MA, Breakefield XO, Beltzer J, Schuback D, Weissleder R, Pardo FS, Ladner R. Isolation, characterization, and recovery of small peptide phage display epitopes selected against viable malignant glioma cells. Cancer Gene Ther. 2001 Jul; 8(7):506-11.
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  579. Ntziachristos V, Weissleder R. Experimental three-dimensional fluorescence reconstruction of diffuse media by use of a normalized Born approximation. Opt Lett. 2001 Jun 15; 26(12):893-5.
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  580. Bremer C, Tung CH, Weissleder R. In vivo molecular target assessment of matrix metalloproteinase inhibition. Nat Med. 2001 Jun; 7(6):743-8.
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  581. Wagenaar DJ, Weissleder R, Hengerer A. Glossary of molecular imaging terminology. Acad Radiol. 2001 May; 8(5):409-20.
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  582. Weissleder R, Mahmood U. Molecular imaging. Radiology. 2001 May; 219(2):316-33.
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  583. Weissleder R. A clearer vision for in vivo imaging. Nat Biotechnol. 2001 Apr; 19(4):316-7.
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  584. Bogdanov A, Tung CH, Bredow S, Weissleder R. DNA binding chelates for nonviral gene delivery imaging. Gene Ther. 2001 Apr; 8(7):515-22.
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  585. Weissleder R, Bogdanov A, Tung CH, Weinmann HJ. Size optimization of synthetic graft copolymers for in vivo angiogenesis imaging. Bioconjug Chem. 2001 Mar-Apr; 12(2):213-9.
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  586. Wunderbaldinger P, Weissleder R. [Experimental and clinical approaches to lymph node imaging]. Radiologe. 2001 Feb; 41(2):121-30.
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  587. Bremer C, Bogdanov AA, Weissleder R. [Imaging of angiogenesis]. Radiologe. 2001 Feb; 41(2):138-45.
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  588. Högemann D, Basilion JP, Weissleder R. [Molecular imaging in magnetic resonance tomography and nuclear medicine]. Radiologe. 2001 Feb; 41(2):116-20.
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  589. Weissleder R. [Experimental radiology in the USA]. Radiologe. 2001 Feb; 41(2):115.
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  590. Bremer C, Ntziachristos V, Mahmood U, Tung CH, Weissleder R. [Progress in optical imaging]. Radiologe. 2001 Feb; 41(2):131-7.
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  591. Bremer C, Weissleder R. In vivo imaging of gene expression:. Acad Radiol. 2001 Jan; 8(1):15-23.
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  592. Simonova M, Wall A, Weissleder R, Bogdanov A. Tyrosinase mutants are capable of prodrug activation in transfected nonmelanotic cells. Cancer Res. 2000 Dec 1; 60(23):6656-62.
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  593. Högemann D, Josephson L, Weissleder R, Basilion JP. Improvement of MRI probes to allow efficient detection of gene expression. Bioconjug Chem. 2000 Nov-Dec; 11(6):941-6.
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  594. Schellingerhout D, Rainov NG, Breakefield XO, Weissleder R. Quantitation of HSV mass distribution in a rodent brain tumor model. Gene Ther. 2000 Oct; 7(19):1648-55.
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  595. Tung CH, Mahmood U, Bredow S, Weissleder R. In vivo imaging of proteolytic enzyme activity using a novel molecular reporter. Cancer Res. 2000 Sep 1; 60(17):4953-8.
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  596. Bogdanov AA, Simonova M, Weissleder R. Engineering membrane proteins for nuclear medicine: applications for gene therapy and cell tracking. Q J Nucl Med. 2000 Sep; 44(3):224-35.
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  597. Wunderbaldinger P, Bogdanov A, Weissleder R. New approaches for imaging in gene therapy. Eur J Radiol. 2000 Jun; 34(3):156-65.
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  598. Bhorade R, Weissleder R, Nakakoshi T, Moore A, Tung CH. Macrocyclic chelators with paramagnetic cations are internalized into mammalian cells via a HIV-tat derived membrane translocation peptide. Bioconjug Chem. 2000 May-Jun; 11(3):301-5.
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  599. Lewin M, Carlesso N, Tung CH, Tang XW, Cory D, Scadden DT, Weissleder R. Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells. Nat Biotechnol. 2000 Apr; 18(4):410-4.
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  600. Weissleder R, Moore A, Mahmood U, Bhorade R, Benveniste H, Chiocca EA, Basilion JP. In vivo magnetic resonance imaging of transgene expression. Nat Med. 2000 Mar; 6(3):351-5.
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  601. Bredow S, Lewin M, Hofmann B, Marecos E, Weissleder R. Imaging of tumour neovasculature by targeting the TGF-beta binding receptor endoglin. Eur J Cancer. 2000 Mar; 36(5):675-81.
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  602. Moore A, Marecos E, Bogdanov A, Weissleder R. Tumoral distribution of long-circulating dextran-coated iron oxide nanoparticles in a rodent model. Radiology. 2000 Feb; 214(2):568-74.
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  603. Lewin M, Bredow S, Sergeyev N, Marecos E, Bogdanov A, Weissleder R. In vivo assessment of vascular endothelial growth factor-induced angiogenesis. Int J Cancer. 1999 Dec 10; 83(6):798-802.
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  604. Mahmood U, Tung CH, Bogdanov A, Weissleder R. Near-infrared optical imaging of protease activity for tumor detection. Radiology. 1999 Dec; 213(3):866-70.
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  605. Bogdanov A, Marecos E, Cheng HC, Chandrasekaran L, Krutzsch HC, Roberts DD, Weissleder R. Treatment of experimental brain tumors with trombospondin-1 derived peptides: an in vivo imaging study. Neoplasia. 1999 Nov; 1(5):438-45.
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  606. Zaharchuk G, Mandeville JB, Bogdanov AA, Weissleder R, Rosen BR, Marota JJ. Cerebrovascular dynamics of autoregulation and hypoperfusion. An MRI study of CBF and changes in total and microvascular cerebral blood volume during hemorrhagic hypotension. Stroke. 1999 Oct; 30(10):2197-204; discussion 2204-5.
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  607. Simonova M, Weissleder R, Sergeyev N, Vilissova N, Bogdanov A. Targeting of green fluorescent protein expression to the cell surface. Biochem Biophys Res Commun. 1999 Sep 7; 262(3):638-42.
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  608. Tung CH, Bredow S, Mahmood U, Weissleder R. Preparation of a cathepsin D sensitive near-infrared fluorescence probe for imaging. Bioconjug Chem. 1999 Sep-Oct; 10(5):892-6.
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  609. Weissleder R. Molecular imaging: exploring the next frontier. Radiology. 1999 Sep; 212(3):609-14.
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  610. Schima W, Saini S, Petersein J, Weissleder R, Harisinghani M, Mayo-Smith W, Hahn PF. MR imaging of the liver with Gd-BOPTA: quantitative analysis of T1-weighted images at two different doses. J Magn Reson Imaging. 1999 Jul; 10(1):80-3.
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  611. Harisinghani MG, Saini S, Weissleder R, Hahn PF, Yantiss RK, Tempany C, Wood BJ, Mueller PR. MR lymphangiography using ultrasmall superparamagnetic iron oxide in patients with primary abdominal and pelvic malignancies: radiographic-pathologic correlation. AJR Am J Roentgenol. 1999 May; 172(5):1347-51.
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  612. Weissleder R, Tung CH, Mahmood U, Bogdanov A. In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat Biotechnol. 1999 Apr; 17(4):375-8.
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  613. Josephson L, Tung CH, Moore A, Weissleder R. High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates. Bioconjug Chem. 1999 Mar-Apr; 10(2):186-91.
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  614. Hofmann B, Bogdanov A, Marecos E, Ebert W, Semmler W, Weissleder R. Mechanism of gadophrin-2 accumulation in tumor necrosis. J Magn Reson Imaging. 1999 Feb; 9(2):336-41.
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  615. Enochs WS, Harsh G, Hochberg F, Weissleder R. Improved delineation of human brain tumors on MR images using a long-circulating, superparamagnetic iron oxide agent. J Magn Reson Imaging. 1999 Feb; 9(2):228-32.
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  616. Bogdanov AA, Lewin M, Weissleder R. Approaches and agents for imaging the vascular system. Adv Drug Deliv Rev. 1999 Apr 5; 37(1-3):279-293.
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  617. Frank H, Loewe R, Loewe C, Oberhuber G, Schwaighofer B, Huber K, Weissleder R. Efficacy of thrombolytic therapy in pulmonary embolism determined by MION-enhanced MRA: an experimental study in rabbits. Invest Radiol. 1998 Dec; 33(12):853-7.
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  618. Moore A, Marecos E, Simonova M, Weissleder R, Bogdanov A. Novel gliosarcoma cell line expressing green fluorescent protein: A model for quantitative assessment of angiogenesis. Microvasc Res. 1998 Nov; 56(3):145-53.
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  619. Zaharchuk G, Bogdanov AA, Marota JJ, Shimizu-Sasamata M, Weisskoff RM, Kwong KK, Jenkins BG, Weissleder R, Rosen BR. Continuous assessment of perfusion by tagging including volume and water extraction (CAPTIVE): a steady-state contrast agent technique for measuring blood flow, relative blood volume fraction, and the water extraction fraction. Magn Reson Med. 1998 Nov; 40(5):666-78.
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  620. Boiselle PM, Patz EF, Vining DJ, Weissleder R, Shepard JA, McLoud TC. Imaging of mediastinal lymph nodes: CT, MR, and FDG PET. Radiographics. 1998 Sep-Oct; 18(5):1061-9.
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  621. Weissleder R, Cheng HC, Marecos E, Kwong K, Bogdanov A. Non-invasive in vivo mapping of tumour vascular and interstitial volume fractions. Eur J Cancer. 1998 Aug; 34(9):1448-54.
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  622. Schellingerhout D, Bogdanov A, Marecos E, Spear M, Breakefield X, Weissleder R. Mapping the in vivo distribution of herpes simplex virions. Hum Gene Ther. 1998 Jul 20; 9(11):1543-9.
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  623. Callahan RJ, Bogdanov A, Fischman AJ, Brady TJ, Weissleder R. Preclinical evaluation and phase I clinical trial of a 99mTc-labeled synthetic polymer used in blood pool imaging. AJR Am J Roentgenol. 1998 Jul; 171(1):137-43.
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  624. de Marco G, Bogdanov A, Marecos E, Moore A, Simonova M, Weissleder R. MR imaging of gene delivery to the central nervous system with an artificial vector. Radiology. 1998 Jul; 208(1):65-71.
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  625. Reimer P, Bader A, Weissleder R. Preclinical assessment of hepatocyte-targeted MR contrast agents in stable human liver cell cultures. J Magn Reson Imaging. 1998 May-Jun; 8(3):687-9.
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  626. Moore A, Basilion JP, Chiocca EA, Weissleder R. Measuring transferrin receptor gene expression by NMR imaging. Biochim Biophys Acta. 1998 Apr 24; 1402(3):239-49.
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  627. Harisinghani MG, Saini S, Hahn PF, Weissleder R, Mueller PR. MR imaging of lymph nodes in patients with primary abdominal and pelvic malignancies using ultrasmall superparamagnetic iron oxide (Combidex). Acad Radiol. 1998 Apr; 5 Suppl 1:S167-9, discussion S183-4.
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  628. Spear MA, Herrlinger U, Rainov N, Pechan P, Weissleder R, Breakefield XO. Targeting gene therapy vectors to CNS malignancies. J Neurovirol. 1998 Apr; 4(2):133-47.
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  629. Mandeville JB, Marota JJ, Kosofsky BE, Keltner JR, Weissleder R, Rosen BR, Weisskoff RM. Dynamic functional imaging of relative cerebral blood volume during rat forepaw stimulation. Magn Reson Med. 1998 Apr; 39(4):615-24.
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  630. Bogdanov A, Simonova M, Weissleder R. Design of metal-binding green fluorescent protein variants. Biochim Biophys Acta. 1998 Apr 1; 1397(1):56-64.
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  631. Schoepf U, Marecos EM, Melder RJ, Jain RK, Weissleder R. Intracellular magnetic labeling of lymphocytes for in vivo trafficking studies. Biotechniques. 1998 Apr; 24(4):642-6, 648-51.
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  632. Marecos E, Weissleder R, Bogdanov A. Antibody-mediated versus nontargeted delivery in a human small cell lung carcinoma model. Bioconjug Chem. 1998 Mar-Apr; 9(2):184-91.
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  633. Moore A, Sergeyev N, Bredow S, Weissleder R. A model system to quantitate tumor burden in locoregional lymph nodes during cancer spread. Invasion Metastasis. 1998-1999; 18(4):192-7.
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  634. Bogdanov A, Weissleder R. The development of in vivo imaging systems to study gene expression. Trends Biotechnol. 1998 Jan; 16(1):5-10.
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  635. Cheng HC, Khan MA, Bogdanov A, Kwong K, Weissleder R. Relative blood volume measurements by magnetic resonance imaging facilitate detection of testicular torsion. Invest Radiol. 1997 Dec; 32(12):763-9.
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  636. Moore A, Weissleder R, Bogdanov A. Uptake of dextran-coated monocrystalline iron oxides in tumor cells and macrophages. J Magn Reson Imaging. 1997 Nov-Dec; 7(6):1140-5.
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  637. Bogdanov A, Petherick P, Marecos E, Weissleder R. In vivo localization of diglycylcysteine-bearing synthetic peptides by nuclear imaging of oxotechnetate transchelation. Nucl Med Biol. 1997 Nov; 24(8):739-42.
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  638. Enochs WS, Petherick P, Bogdanova A, Mohr U, Weissleder R. Paramagnetic metal scavenging by melanin: MR imaging. Radiology. 1997 Aug; 204(2):417-23.
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  639. Weissleder R, Simonova M, Bogdanova A, Bredow S, Enochs WS, Bogdanov A. MR imaging and scintigraphy of gene expression through melanin induction. Radiology. 1997 Aug; 204(2):425-9.
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  640. Mandeville JB, Moore J, Chesler DA, Garrido L, Weissleder R, Weisskoff RM. Dynamic liver imaging with iron oxide agents: effects of size and biodistribution on contrast. Magn Reson Med. 1997 Jun; 37(6):885-90.
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  641. Harisinghani MG, Saini S, Weissleder R, Halpern EF, Schima W, Rubin DL, Stillman AE, Sica GT, Small WC, Hahn PF. Differentiation of liver hemangiomas from metastases and hepatocellular carcinoma at MR imaging enhanced with blood-pool contrast agent Code-7227. Radiology. 1997 Mar; 202(3):687-91.
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  642. Reimer P, Bader A, Weissleder R. Application of a stable cell culture assay for the functional assessment of novel MR contrast agents. Eur Radiol. 1997; 7(4):527-31.
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  643. Weissleder R, Cheng HC, Bogdanova A, Bogdanov A. Magnetically labeled cells can be detected by MR imaging. J Magn Reson Imaging. 1997 Jan-Feb; 7(1):258-63.
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  644. Bogdanov A, Wright SC, Marecos EM, Bogdanova A, Martin C, Petherick P, Weissleder R. A long-circulating co-polymer in "passive targeting" to solid tumors. J Drug Target. 1997; 4(5):321-30.
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  645. Zimmer C, Wright SC, Engelhardt RT, Johnson GA, Kramm C, Breakefield XO, Weissleder R. Tumor cell endocytosis imaging facilitates delineation of the glioma-brain interface. Exp Neurol. 1997 Jan; 143(1):61-9.
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  646. Weissleder R. Can gadolinium be safely given in renal failure? AJR Am J Roentgenol. 1996 Jul; 167(1):278-9.
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  647. Mohr U, Weissleder R. [Lymph node diagnosis with imaging methods. An overview with special reference to recent developments in the area of MR contrast media]. Z Lymphol. 1996 Jun; 20(1):15-20.
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  648. Shen TT, Bogdanov A, Bogdanova A, Poss K, Brady TJ, Weissleder R. Magnetically labeled secretin retains receptor affinity to pancreas acinar cells. Bioconjug Chem. 1996 May-Jun; 7(3):311-6.
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  649. Remsen LG, McCormick CI, Roman-Goldstein S, Nilaver G, Weissleder R, Bogdanov A, Hellström I, Kroll RA, Neuwelt EA. MR of carcinoma-specific monoclonal antibody conjugated to monocrystalline iron oxide nanoparticles: the potential for noninvasive diagnosis. AJNR Am J Neuroradiol. 1996 Mar; 17(3):411-8.
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  650. Stiskal M, Schwickert HC, Demsar F, Roberts TP, Szolar D, Weissleder R, Brasch RC. Contrast enhancement in experimental radiation-induced liver injury: comparison of hepatocellular and reticuloendothelial particulate contrast agents. J Magn Reson Imaging. 1996 Mar-Apr; 6(2):286-90.
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  651. Petersein J, Saini S, Weissleder R. Liver. II: Iron oxide-based reticuloendothelial contrast agents for MR imaging. Clinical review. Magn Reson Imaging Clin N Am. 1996 Feb; 4(1):53-60.
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  652. Gupta H, Weissleder R. Targeted contrast agents in MR imaging. Magn Reson Imaging Clin N Am. 1996 Feb; 4(1):171-84.
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  653. Reimer P, Weissleder R. [Development and experimental use of receptor-specific MR contrast media]. Radiologe. 1996 Feb; 36(2):153-63.
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  654. Harika L, Weissleder R, Poss K, Papisov MI. Macromolecular intravenous contrast agent for MR lymphography: characterization and efficacy studies. Radiology. 1996 Feb; 198(2):365-70.
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  655. Papisov M, Weissleder R. Drug delivery to lymphatic tissue. Crit Rev Ther Drug Carrier Syst. 1996; 13(1-2):57-84.
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  656. Bogdanov AA, Martin C, Bogdanova AV, Brady TJ, Weissleder R. An adduct of cis-diamminedichloroplatinum(II) and poly(ethylene glycol)poly(L-lysine)-succinate: synthesis and cytotoxic properties. Bioconjug Chem. 1996 Jan-Feb; 7(1):144-9.
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  657. Gupta H, Wilkinson RA, Bogdanov AA, Callahan RJ, Weissleder R. Inflammation: imaging with methoxy poly(ethylene glycol)-poly-L-lysine-DTPA, a long-circulating graft copolymer. Radiology. 1995 Dec; 197(3):665-9.
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  658. Muldoon LL, Nilaver G, Kroll RA, Pagel MA, Breakefield XO, Chiocca EA, Davidson BL, Weissleder R, Neuwelt EA. Comparison of intracerebral inoculation and osmotic blood-brain barrier disruption for delivery of adenovirus, herpesvirus, and iron oxide particles to normal rat brain. Am J Pathol. 1995 Dec; 147(6):1840-51.
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  659. Rainov NG, Zimmer C, Chase M, Kramm CM, Chiocca EA, Weissleder R, Breakefield XO. Selective uptake of viral and monocrystalline particles delivered intra-arterially to experimental brain neoplasms. Hum Gene Ther. 1995 Dec; 6(12):1543-52.
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  660. Zimmer C, Weissleder R, Poss K, Bogdanova A, Wright SC, Enochs WS. MR imaging of phagocytosis in experimental gliomas. Radiology. 1995 Nov; 197(2):533-8.
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  661. Schulze E, Ferrucci JT, Poss K, Lapointe L, Bogdanova A, Weissleder R. Cellular uptake and trafficking of a prototypical magnetic iron oxide label in vitro. Invest Radiol. 1995 Oct; 30(10):604-10.
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  662. Zimmer C, Weissleder R, O'Connor D, LaPointe L, Brady TJ, Enochs WS. Cerebral iron oxide distribution: in vivo mapping with MR imaging. Radiology. 1995 Aug; 196(2):521-7.
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  663. Gupta H, Weissleder R, Bogdanov AA, Brady TJ. Experimental gastrointestinal hemorrhage: detection with contrast-enhanced MR imaging and scintigraphy. Radiology. 1995 Jul; 196(1):239-44.
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  664. Petropoulos AE, Schaffer BK, Cheney ML, Enochs S, Zimmer C, Weissleder R. MR imaging of neuronal transport in the guinea pig facial nerve: initial findings. Acta Otolaryngol. 1995 Jul; 115(4):512-6.
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  665. Weissleder R, Poss K, Wilkinson R, Zhou C, Bogdanov A. Quantitation of slow drug release from an implantable and degradable gentamicin conjugate by in vivo magnetic resonance imaging. Antimicrob Agents Chemother. 1995 Apr; 39(4):839-45.
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  666. Frank H, Weissleder R, Papisov M. [Presentation and quantification of acute myocardial infarct using antibody-bound MR contrast medium]. Z Kardiol. 1995 Apr; 84(4):311-5.
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  667. Harika L, Weissleder R, Poss K, Zimmer C, Papisov MI, Brady TJ. MR lymphography with a lymphotropic T1-type MR contrast agent: Gd-DTPA-PGM. Magn Reson Med. 1995 Jan; 33(1):88-92.
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  668. Bader A, Reimer P, Knop E, Böker K, Christians U, Weissleder R, Sewing KF. An organotypical in vitro model of the liver parenchyma for uptake studies of diagnostic MR receptor agents. Magn Reson Imaging. 1995; 13(7):991-1002.
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  669. Weissleder R. Liver MR imaging with iron oxides: toward consensus and clinical practice. Radiology. 1994 Dec; 193(3):593-5.
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  670. Bogdanov AA, Callahan RJ, Wilkinson RA, Martin C, Cameron JA, Fischman AJ, Brady TJ, Weissleder R. Synthetic copolymer kit for radionuclide blood-pool imaging. J Nucl Med. 1994 Nov; 35(11):1880-6.
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  671. Reimer P, Weissleder R, Shen T, Knoefel WT, Brady TJ. Pancreatic receptors: initial feasibility studies with a targeted contrast agent for MR imaging. Radiology. 1994 Nov; 193(2):527-31.
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  672. van Everdingen KJ, Enochs WS, Bhide PG, Nossiff N, Papisov M, Bogdanov A, Brady TJ, Weissleder R. Determinants of in vivo MR imaging of slow axonal transport. Radiology. 1994 Nov; 193(2):485-91.
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  673. Bogdanov AA, Martin C, Weissleder R, Brady TJ. Trapping of dextran-coated colloids in liposomes by transient binding to aminophospholipid: preparation of ferrosomes. Biochim Biophys Acta. 1994 Jul 13; 1193(1):212-8.
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  674. Enochs WS, Weissleder R. MR imaging of the peripheral nervous system. J Magn Reson Imaging. 1994 May-Jun; 4(3):251-7.
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  675. Frank H, Weissleder R, Bogdanov AA, Brady TJ. Detection of pulmonary emboli by using MR angiography with MPEG-PL-GdDTPA: an experimental study in rabbits. AJR Am J Roentgenol. 1994 May; 162(5):1041-6.
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  676. Lu DS, Saini S, Hahn PF, Goldberg M, Lee MJ, Weissleder R, Gerard B, Halpern E, Cats A. T2-weighted MR imaging of the upper part of the abdomen: should fat suppression be used routinely? AJR Am J Roentgenol. 1994 May; 162(5):1095-100.
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  677. Reimer P, Saini S, Kwong KK, Cohen MS, Weissleder R, Brady TJ. Dynamic gadolinium-enhanced echo-planar MR imaging of the liver: effect of pulse sequence and dose on enhancement. J Magn Reson Imaging. 1994 May-Jun; 4(3):331-5.
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  678. Neuwelt EA, Weissleder R, Nilaver G, Kroll RA, Roman-Goldstein S, Szumowski J, Pagel MA, Jones RS, Remsen LG, McCormick CI, et al. Delivery of virus-sized iron oxide particles to rodent CNS neurons. Neurosurgery. 1994 Apr; 34(4):777-84.
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  679. Weissleder R, Heautot JF, Schaffer BK, Nossiff N, Papisov MI, Bogdanov A, Brady TJ. MR lymphography: study of a high-efficiency lymphotrophic agent. Radiology. 1994 Apr; 191(1):225-30.
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  680. Frank H, Weissleder R, Brady TJ. Enhancement of MR angiography with iron oxide: preliminary studies in whole-blood phantom and in animals. AJR Am J Roentgenol. 1994 Jan; 162(1):209-13.
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  681. Weissleder R, Bogdanov A, Frank H, Nossiff N, Bogdanova A, Schaffer BK, Brady T, Wittenberg J. AUR Memorial Award 1993. A drug system (PDH) for interventional radiology. Synthesis, properties, and efficacy. Invest Radiol. 1993 Dec; 28(12):1083-9.
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  682. Enochs WS, Schaffer B, Bhide PG, Nossiff N, Papisov M, Bogdanov A, Brady TJ, Weissleder R. MR imaging of slow axonal transport in vivo. Exp Neurol. 1993 Oct; 123(2):235-42.
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  683. Bogdanov AA, Weissleder R, Frank HW, Bogdanova AV, Nossif N, Schaffer BK, Tsai E, Papisov MI, Brady TJ. A new macromolecule as a contrast agent for MR angiography: preparation, properties, and animal studies. Radiology. 1993 Jun; 187(3):701-6.
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  684. Shen T, Weissleder R, Papisov M, Bogdanov A, Brady TJ. Monocrystalline iron oxide nanocompounds (MION): physicochemical properties. Magn Reson Med. 1993 May; 29(5):599-604.
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  685. Weissleder R, Wang YM, Papisov M, Bogdanov A, Schaffer B, Brady TJ, Wittenberg J. Polymeric contrast agents for MR imaging of adrenal glands. J Magn Reson Imaging. 1993 Jan-Feb; 3(1):93-7.
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  686. Schaffer BK, Linker C, Papisov M, Tsai E, Nossiff N, Shibata T, Bogdanov A, Brady TJ, Weissleder R. MION-ASF: biokinetics of an MR receptor agent. Magn Reson Imaging. 1993; 11(3):411-7.
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  687. Reimer P, Weissleder R, Nickeleit V, Brady TJ. Animal models for magnetic resonance imaging research of the liver. Invest Radiol. 1992 May; 27(5):390-3.
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  688. Reimer P, Kwong KK, Weisskoff R, Cohen MS, Brady TJ, Weissleder R. Dynamic signal intensity changes in liver with superparamagnetic MR contrast agents. J Magn Reson Imaging. 1992 Mar-Apr; 2(2):177-81.
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  689. Weissleder R, Bogdanov A, Papisov M. Drug targeting in magnetic resonance imaging. Magn Reson Q. 1992 Mar; 8(1):55-63.
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  690. Reimer P, Weissleder R, Wittenberg J, Brady TJ. Receptor-directed contrast agents for MR imaging: preclinical evaluation with affinity assays. Radiology. 1992 Feb; 182(2):565-9.
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  691. Weissleder R, Lee AS, Khaw BA, Shen T, Brady TJ. Antimyosin-labeled monocrystalline iron oxide allows detection of myocardial infarct: MR antibody imaging. Radiology. 1992 Feb; 182(2):381-5.
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  692. Weissleder R. Target-specific superparamagnetic MR contrast agents. Magn Reson Med. 1991 Dec; 22(2):209-12; discussion 213-5.
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  693. Weissleder R, Lee AS, Fischman AJ, Reimer P, Shen T, Wilkinson R, Callahan RJ, Brady TJ. Polyclonal human immunoglobulin G labeled with polymeric iron oxide: antibody MR imaging. Radiology. 1991 Oct; 181(1):245-9.
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  694. Chew FS, Weissleder R. Radiation-induced osteochondroma. AJR Am J Roentgenol. 1991 Oct; 157(4):792.
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  695. Chew FS, Weissleder R. Mediastinal thymolipoma. AJR Am J Roentgenol. 1991 Sep; 157(3):468.
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  696. Reimer P, Weissleder R, Brady TJ, Yeager AE, Baldwin BH, Tennant BC, Wittenberg J. Experimental hepatocellular carcinoma: MR receptor imaging. Radiology. 1991 Sep; 180(3):641-5.
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  697. Senéterre E, Weissleder R, Jaramillo D, Reimer P, Lee AS, Brady TJ, Wittenberg J. Bone marrow: ultrasmall superparamagnetic iron oxide for MR imaging. Radiology. 1991 May; 179(2):529-33.
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  698. Reimer P, Weissleder R, Lee AS, Buettner S, Wittenberg J, Brady TJ. Asialoglycoprotein receptor function in benign liver disease: evaluation with MR imaging. Radiology. 1991 Mar; 178(3):769-74.
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  699. Lee AS, Weissleder R, Brady TJ, Wittenberg J. Lymph nodes: microstructural anatomy at MR imaging. Radiology. 1991 Feb; 178(2):519-22.
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  700. Josephson L, Groman E, Weissleder R. Contrast agents for magnetic resonance imaging of the liver. Targeted Diagn Ther. 1991; 4:163-87.
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  701. Reimer P, Weissleder R, Lee AS, Wittenberg J, Brady TJ. Receptor imaging: application to MR imaging of liver cancer. Radiology. 1990 Dec; 177(3):729-34.
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  702. Weissleder R, Reimer P, Lee AS, Wittenberg J, Brady TJ. MR receptor imaging: ultrasmall iron oxide particles targeted to asialoglycoprotein receptors. AJR Am J Roentgenol. 1990 Dec; 155(6):1161-7.
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  703. Fretz CJ, Stark DD, Metz CE, Elizondo G, Weissleder R, Shen JH, Wittenberg J, Simeone J, Ferrucci JT. Detection of hepatic metastases: comparison of contrast-enhanced CT, unenhanced MR imaging, and iron oxide-enhanced MR imaging. AJR Am J Roentgenol. 1990 Oct; 155(4):763-70.
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  704. Hahn PF, Stark DD, Lewis JM, Saini S, Elizondo G, Weissleder R, Fretz CJ, Ferrucci JT. First clinical trial of a new superparamagnetic iron oxide for use as an oral gastrointestinal contrast agent in MR imaging. Radiology. 1990 Jun; 175(3):695-700.
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  705. Weissleder R, Elizondo G, Wittenberg J, Rabito CA, Bengele HH, Josephson L. Ultrasmall superparamagnetic iron oxide: characterization of a new class of contrast agents for MR imaging. Radiology. 1990 May; 175(2):489-93.
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  706. Weissleder R, Elizondo G, Wittenberg J, Lee AS, Josephson L, Brady TJ. Ultrasmall superparamagnetic iron oxide: an intravenous contrast agent for assessing lymph nodes with MR imaging. Radiology. 1990 May; 175(2):494-8.
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  707. Elizondo G, Weissleder R, Stark DD, Guerra J, Garza J, Fretz CJ, Todd LE, Ferrucci JT. Hepatic cirrhosis and hepatitis: MR imaging enhanced with superparamagnetic iron oxide. Radiology. 1990 Mar; 174(3 Pt 1):797-801.
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  708. Hahn PF, Stark DD, Weissleder R, Elizondo G, Saini S, Ferrucci JT. Clinical application of superparamagnetic iron oxide to MR imaging of tissue perfusion in vascular liver tumors. Radiology. 1990 Feb; 174(2):361-6.
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  709. Hahn PF, Stark DD, Saini S, Rummeny E, Elizondo G, Weissleder R, Wittenberg J, Ferrucci JT. The differential diagnosis of ringed hepatic lesions in MR imaging. AJR Am J Roentgenol. 1990 Feb; 154(2):287-90.
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  710. Rummeny E, Saini S, Stark DD, Weissleder R, Compton CC, Ferrucci JT. Detection of hepatic metastases with MR imaging: spin-echo vs phase-contrast pulse sequences at 0.6 T. AJR Am J Roentgenol. 1989 Dec; 153(6):1207-11.
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  711. Weissleder R, Thrall JH. The lymphatic system: diagnostic imaging studies. Radiology. 1989 Aug; 172(2):315-7.
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  712. Fretz CJ, Elizondo G, Weissleder R, Hahn PF, Stark DD, Ferrucci JT. Superparamagnetic iron oxide-enhanced MR imaging: pulse sequence optimization for detection of liver cancer. Radiology. 1989 Aug; 172(2):393-7.
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  713. Weissleder R, Elizondo G, Josephson L, Compton CC, Fretz CJ, Stark DD, Ferrucci JT. Experimental lymph node metastases: enhanced detection with MR lymphography. Radiology. 1989 Jun; 171(3):835-9.
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  714. Rummeny E, Weissleder R, Sironi S, Stark DD, Comptom CC, Hahn PF, Saini S, Wittenberg J, Ferrucci JT. Central scars in primary liver tumors: MR features, specificity, and pathologic correlation. Radiology. 1989 May; 171(2):323-6.
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  715. Dousset M, Weissleder R, Hendrick RE, Stark DD, Fretz CJ, Elizondo G, Hahn PF, Saini S, Ferrucci JT. Short TI inversion-recovery imaging of the liver: pulse-sequence optimization and comparison with spin-echo imaging. Radiology. 1989 May; 171(2):327-33.
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  716. Weissleder R, Stark DD. Magnetic resonance imaging of the liver. Magn Reson Q. 1989 Apr; 5(2):97-121.
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  717. Rummeny E, Saini S, Wittenberg J, Compton C, Hahn PF, Mueller PR, Simeone JF, Stark DD, Weissleder R, Dousset MG, et al. MR imaging of liver neoplasms. AJR Am J Roentgenol. 1989 Mar; 152(3):493-9.
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  718. Weissleder H, Weissleder R. Interstitial lymphangiography: initial clinical experience with a dimeric nonionic contrast agent. Radiology. 1989 Feb; 170(2):371-4.
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  719. Weissleder R, Stark DD. Magnetic resonance imaging of liver tumors. Semin Ultrasound CT MR. 1989 Feb; 10(1):63-77.
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  720. Weissleder R, Stark DD, Engelstad BL, Bacon BR, Compton CC, White DL, Jacobs P, Lewis J. Superparamagnetic iron oxide: pharmacokinetics and toxicity. AJR Am J Roentgenol. 1989 Jan; 152(1):167-73.
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  721. Weissleder R, Elizondo G, Stark DD, Hahn PF, Marfil J, Gonzalez JF, Saini S, Todd LE, Ferrucci JT. The diagnosis of splenic lymphoma by MR imaging: value of superparamagnetic iron oxide. AJR Am J Roentgenol. 1989 Jan; 152(1):175-80.
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  722. Chen MC, Tsang YM, Stark DD, Weissleder R, Saini S, Brandhorst J, White DL, Engelstad BL, Ferrucci JT. Hepatic metastases: rat models for imaging research. Magn Reson Imaging. 1989 Jan-Feb; 7(1):1-8.
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  723. Rummeny E, Weissleder R, Stark DD, Saini S, Compton CC, Bennett W, Hahn PF, Wittenberg J, Malt RA, Ferrucci JT. Primary liver tumors: diagnosis by MR imaging. AJR Am J Roentgenol. 1989 Jan; 152(1):63-72.
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  724. Weissleder R, Stark DD, Elizondo G, Hahn PF, Compton C, Saini S, Wittenberg J, Ferrucci JT. MRI of hepatic lymphoma. Magn Reson Imaging. 1988 Nov-Dec; 6(6):675-81.
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  725. Weissleder R, Hahn PF, Stark DD, Elizondo G, Saini S, Todd LE, Wittenberg J, Ferrucci JT. Superparamagnetic iron oxide: enhanced detection of focal splenic tumors with MR imaging. Radiology. 1988 Nov; 169(2):399-403.
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  726. Rummeny E, Weissleder R, Stark DD, Elizondo G, Ferrucci JT. [Magnetic resonance tomography of focal liver and spleen lesions. Experiences using ferrite, a new RES-specific MR contrast medium]. Radiologe. 1988 Aug; 28(8):380-6.
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  727. Stark DD, Weissleder R, Elizondo G, Hahn PF, Saini S, Todd LE, Wittenberg J, Ferrucci JT. Superparamagnetic iron oxide: clinical application as a contrast agent for MR imaging of the liver. Radiology. 1988 Aug; 168(2):297-301.
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  728. Wittenberg J, Stark DD, Forman BH, Hahn PF, Saini S, Weissleder R, Rummeny E, Ferrucci JT. Differentiation of hepatic metastases from hepatic hemangiomas and cysts by using MR imaging. AJR Am J Roentgenol. 1988 Jul; 151(1):79-84.
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  729. Weissleder H, Weissleder R. Lymphedema: evaluation of qualitative and quantitative lymphoscintigraphy in 238 patients. Radiology. 1988 Jun; 167(3):729-35.
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  730. Weissleder R, Stark DD, Compton CC, Simeone JF, Ferrucci JT. Cholecystitis: diagnosis by MR imaging. Magn Reson Imaging. 1988 May-Jun; 6(3):345-8.
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  731. Hahn PF, Weissleder R, Stark DD, Saini S, Elizondo G, Ferrucci JT. MR imaging of focal splenic tumors. AJR Am J Roentgenol. 1988 Apr; 150(4):823-7.
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  732. Tsang YM, Stark DD, Chen MC, Weissleder R, Wittenberg J, Ferrucci JT. Hepatic micrometastases in the rat: ferrite-enhanced MR imaging. Radiology. 1988 Apr; 167(1):21-4.
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  733. Weissleder R, Saini S, Stark DD, Wittenberg J, Ferrucci JT. Dual-contrast MR imaging of liver cancer in rats. AJR Am J Roentgenol. 1988 Mar; 150(3):561-6.
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  734. Weissleder R, Stark DD, Rummeny EJ, Compton CC, Ferrucci JT. Splenic lymphoma: ferrite-enhanced MR imaging in rats. Radiology. 1988 Feb; 166(2):423-30.
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  735. Weissleder R, Saini S, Stark DD, Elizondo G, Compton C, Wittenberg J, Ferrucci JT. Pyogenic liver abscess: contrast-enhanced MR imaging in rats. AJR Am J Roentgenol. 1988 Jan; 150(1):115-20.
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  736. Weissleder R, Stark DD, Compton CC, Wittenberg J, Ferrucci JT. Ferrite-enhanced MR imaging of hepatic lymphoma: an experimental study in rats. AJR Am J Roentgenol. 1987 Dec; 149(6):1161-5.
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  737. Elizondo G, Weissleder R, Stark DD, Todd LE, Compton C, Wittenberg J, Ferrucci JT. Amebic liver abscess: diagnosis and treatment evaluation with MR imaging. Radiology. 1987 Dec; 165(3):795-800.
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  738. Weissleder R, Elizondo G, Stark DD. Sonographic diagnosis of subclavian and internal jugular vein thrombosis. J Ultrasound Med. 1987 Oct; 6(10):577-87.
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  739. Weissleder R, Hahn PF, Stark DD, Rummeny E, Saini S, Wittenberg J, Ferrucci JT. MR imaging of splenic metastases: ferrite-enhanced detection in rats. AJR Am J Roentgenol. 1987 Oct; 149(4):723-6.
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  740. Weissleder R, Galarza DA, Garza MA. Lupus nephritis: classification, clinical features, and treatment. Rev Invest Clin. 1987 Jul-Sep; 39(3):263-76.
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  741. Weissleder R, Marfil A, Martinez HR, Rangel-Guerra RA. Limb girdle type muscular dystrophy associated with a Wolff-Parkinson-White syndrome. J Neurol Neurosurg Psychiatry. 1987 Apr; 50(4):500-1.
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