Harvard Catalyst Profiles

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Roby Paul Bhattacharyya, M.D.

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Biography
UCSF, San Francisco, CAPhD06/2007Biochemistry and Molecular Biology
UCSF, San Francisco, CAMD06/2007Medicine
University of Chicago, Chicago, ILMS06/1998Biochemistry and Molecular Biology
University of Chicago, Chicago, ILBS06/1998Biological Chemistry

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AI153405 (BHATTACHARYYA, ROBY PAUL) Jul 1, 2020 - Jun 30, 2025
    NIH/NIAID
    Rapid fungal identification and antifungal susceptibility testing through quantitative, multiplexed RNA detection
    Role: Principal Investigator
  2. K08AI119157 (BHATTACHARYYA, ROBY PAUL) Jul 1, 2015 - Jun 30, 2019
    NIH/NIAID
    Bioinformatic and functional analysis of antibiotic-responsive small non-coding RNAs in bacterial pathogens
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Chewcharat A, Chang YT, Sise ME, Bhattacharyya RP, Murray M, Nigwekar SU. Phase 3 Randomized Controlled Trials on Exclusion of Participants with Kidney Disease in COVID-19. Kidney Int Rep. 2020 Oct 21. PMID: 33106779.
    Citations:    
  2. Reyes M, Filbin MR, Bhattacharyya RP, Sonny A, Mehta A, Billman K, Kays KR, Pinilla-Vera M, Benson ME, Cosimi LA, Hung DT, Levy BD, Villani AC, Sade-Feldman M, Baron RM, Goldberg MB, Blainey PC, Hacohen N. Induction of a regulatory myeloid program in bacterial sepsis and severe COVID-19. bioRxiv. 2020 Sep 02. PMID: 32908980.
    Citations:    
  3. Tucker NR, Chaffin M, Bedi KC, Papangeli I, Akkad AD, Arduini A, Hayat S, Eraslan G, Muus C, Bhattacharyya RP, Stegmann CM, Margulies KB, Ellinor PT. Myocyte-Specific Upregulation of ACE2 in Cardiovascular Disease: Implications for SARS-CoV-2-Mediated Myocarditis. Circulation. 2020 08 18; 142(7):708-710. PMID: 32795091.
    Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
  4. Adamsick ML, Gandhi RG, Bidell MR, Elshaboury RH, Bhattacharyya RP, Kim AY, Nigwekar S, Rhee EP, Sise ME. Remdesivir in Patients with Acute or Chronic Kidney Disease and COVID-19. J Am Soc Nephrol. 2020 07; 31(7):1384-1386. PMID: 32513665.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  5. Reyes M, Filbin MR, Bhattacharyya RP, Billman K, Eisenhaure T, Hung DT, Levy BD, Baron RM, Blainey PC, Goldberg MB, Hacohen N. An immune-cell signature of bacterial sepsis. Nat Med. 2020 03; 26(3):333-340. PMID: 32066974.
    Citations: 4     Fields:    Translation:HumansCells
  6. Betin V, Penaranda C, Bandyopadhyay N, Yang R, Abitua A, Bhattacharyya RP, Fan A, Avraham R, Livny J, Shoresh N, Hung DT. Hybridization-based capture of pathogen mRNA enables paired host-pathogen transcriptional analysis. Sci Rep. 2019 12 17; 9(1):19244. PMID: 31848386.
    Citations: 1     Fields:    
  7. Bhattacharyya RP, Bandyopadhyay N, Ma P, Son SS, Liu J, He LL, Wu L, Khafizov R, Boykin R, Cerqueira GC, Pironti A, Rudy RF, Patel MM, Yang R, Skerry J, Nazarian E, Musser KA, Taylor J, Pierce VM, Earl AM, Cosimi LA, Shoresh N, Beechem J, Livny J, Hung DT. Simultaneous detection of genotype and phenotype enables rapid and accurate antibiotic susceptibility determination. Nat Med. 2019 12; 25(12):1858-1864. PMID: 31768064.
    Citations: 9     Fields:    Translation:Humans
  8. Wadsworth CB, Sater MRA, Bhattacharyya RP, Grad YH. Impact of Species Diversity on the Design of RNA-Based Diagnostics for Antibiotic Resistance in Neisseria gonorrhoeae. Antimicrob Agents Chemother. 2019 08; 63(8). PMID: 31138575.
    Citations: 6     Fields:    Translation:HumansCells
  9. Bhattacharyya RP, Walker M, Boykin R, Son SS, Liu J, Hachey AC, Ma P, Wu L, Choi K, Cummins KC, Benson M, Skerry J, Ryu H, Wong SY, Goldberg MB, Han J, Pierce VM, Cosimi LA, Shoresh N, Livny J, Beechem J, Hung DT. Rapid identification and phylogenetic classification of diverse bacterial pathogens in a multiplexed hybridization assay targeting ribosomal RNA. Sci Rep. 2019 03 14; 9(1):4516. PMID: 30872641.
    Citations:    Fields:    Translation:Cells
  10. Bhattacharyya RP, Thakku SG, Hung DT. Harnessing CRISPR Effectors for Infectious Disease Diagnostics. ACS Infect Dis. 2018 09 14; 4(9):1278-1282. PMID: 30113801.
    Citations: 5     Fields:    Translation:HumansCells
  11. Bhattacharyya RP, Flores EJ, Azar MM. Case 30-2017. A 65-Year-Old Woman with Altered Mental Status, Bacteremia, and Acute Liver Failure. N Engl J Med. 2017 Sep 28; 377(13):1274-1282. PMID: 28953442.
    Citations:    Fields:    Translation:HumansCells
  12. Gootenberg JS, Abudayyeh OO, Lee JW, Essletzbichler P, Dy AJ, Joung J, Verdine V, Donghia N, Daringer NM, Freije CA, Myhrvold C, Bhattacharyya RP, Livny J, Regev A, Koonin EV, Hung DT, Sabeti PC, Collins JJ, Zhang F. Nucleic acid detection with CRISPR-Cas13a/C2c2. Science. 2017 04 28; 356(6336):438-442. PMID: 28408723.
    Citations: 159     Fields:    Translation:HumansCells
  13. Kim S, De Jonghe J, Kulesa AB, Feldman D, Vatanen T, Bhattacharyya RP, Berdy B, Gomez J, Nolan J, Epstein S, Blainey PC. High-throughput automated microfluidic sample preparation for accurate microbial genomics. Nat Commun. 2017 01 27; 8:13919. PMID: 28128213.
    Citations: 12     Fields:    Translation:HumansCellsPHPublic Health
  14. Wertheim BM, Aguirre AJ, Bhattacharyya RP, Chorba J, Jadhav AP, Kerry VB, Macklin EA, Motyckova G, Raju S, Lewandrowski K, Hunt DP, Wright DE. An Educational and Administrative Intervention to Promote Rational Laboratory Test Ordering on an Academic General Medicine Service. Am J Med. 2017 Jan; 130(1):47-53. PMID: 27619354.
    Citations: 3     Fields:    Translation:Humans
  15. Baggett MV, Gonzalez RG, Bhattacharyya RP, Mahowald MA. CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 4-2016. A 58-Year-Old Woman with a Skin Ulcer, Fever, and Lymphadenopathy. N Engl J Med. 2016 Feb 11; 374(6):573-81. PMID: 26863359.
    Citations: 1     Fields:    Translation:Humans
  16. Hou HW, Bhattacharyya RP, Hung DT, Han J. Direct detection and drug-resistance profiling of bacteremias using inertial microfluidics. Lab Chip. 2015 May 21; 15(10):2297-307. PMID: 25882432.
    Citations: 21     Fields:    Translation:HumansCells
  17. Shishkin AA, Giannoukos G, Kucukural A, Ciulla D, Busby M, Surka C, Chen J, Bhattacharyya RP, Rudy RF, Patel MM, Novod N, Hung DT, Gnirke A, Garber M, Guttman M, Livny J. Simultaneous generation of many RNA-seq libraries in a single reaction. Nat Methods. 2015 Apr; 12(4):323-5. PMID: 25730492.
    Citations: 53     Fields:    Translation:Cells
  18. Wivagg CN, Bhattacharyya RP, Hung DT. Mechanisms of ß-lactam killing and resistance in the context of Mycobacterium tuberculosis. J Antibiot (Tokyo). 2014 Sep; 67(9):645-54. PMID: 25052484.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  19. Gonzalez A, Certain L, Bhattacharyya RP. A 52-year-old Cuban immigrant with weight loss, dyspnea, and fever. Splenic tuberculosis. Clin Infect Dis. 2011 Feb 01; 52(3):368; discuaaion 418-20. PMID: 21217183.
    Citations:    Fields:    Translation:Humans
  20. Bhattacharyya RP, Reményi A, Good MC, Bashor CJ, Falick AM, Lim WA. The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway. Science. 2006 Feb 10; 311(5762):822-6. PMID: 16424299.
    Citations: 120     Fields:    Translation:AnimalsCells
  21. Bhattacharyya RP, Reményi A, Yeh BJ, Lim WA. Domains, motifs, and scaffolds: the role of modular interactions in the evolution and wiring of cell signaling circuits. Annu Rev Biochem. 2006; 75:655-80. PMID: 16756506.
    Citations: 184     Fields:    Translation:HumansAnimalsCells
  22. Reményi A, Good MC, Bhattacharyya RP, Lim WA. The role of docking interactions in mediating signaling input, output, and discrimination in the yeast MAPK network. Mol Cell. 2005 Dec 22; 20(6):951-62. PMID: 16364919.
    Citations: 76     Fields:    Translation:AnimalsCells
  23. Dueber JE, Yeh BJ, Bhattacharyya RP, Lim WA. Rewiring cell signaling: the logic and plasticity of eukaryotic protein circuitry. Curr Opin Struct Biol. 2004 Dec; 14(6):690-9. PMID: 15582393.
    Citations: 50     Fields:    Translation:HumansAnimalsCells
  24. Zarrinpar A, Bhattacharyya RP, Nittler MP, Lim WA. Sho1 and Pbs2 act as coscaffolds linking components in the yeast high osmolarity MAP kinase pathway. Mol Cell. 2004 Jun 18; 14(6):825-32. PMID: 15200959.
    Citations: 42     Fields:    Translation:AnimalsCells
  25. Zarrinpar A, Bhattacharyya RP, Lim WA. The structure and function of proline recognition domains. Sci STKE. 2003 Apr 22; 2003(179):RE8. PMID: 12709533.
    Citations: 116     Fields:    Translation:HumansAnimalsCells
  26. Bhattacharyya RP, Sosnick TR. Viscosity dependence of the folding kinetics of a dimeric and monomeric coiled coil. Biochemistry. 1999 Feb 23; 38(8):2601-9. PMID: 10029555.
    Citations: 20     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.