Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

profileDavid Borsook, Ph.D., M.B.,B.Ch.

TitleProfessor of Anaesthesia
InstitutionBoston Children's Hospital
DepartmentAnaesthesia
AddressChildren's Hospital
Division of Pain Medicine
9 Hope Avenue
Waltham MA 02453
Phone617/355-2303
vCardDownload vCard (login for email)

Collapse Mentoring 
Collapse completed student projects
The Lateralization of Trigeminal Pain Processing in the Brain
Summer, 06/15/09 - 07/31/09

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Hodkinson DJ, Wilcox SL, Veggeberg R, Noseda R, Burstein R, Borsook D, Becerra L. Increased Amplitude of Thalamocortical Low-Frequency Oscillations in Patients with Migraine. J Neurosci. 2016 Jul 27; 36(30):8026-36. PMID: 27466345.
    View in: PubMed
  2. Wilcox SL, Veggeberg R, Lemme J, Hodkinson DJ, Scrivani S, Burstein R, Becerra L, Borsook D. Increased Functional Activation of Limbic Brain Regions during Negative Emotional Processing in Migraine. Front Hum Neurosci. 2016; 10:366. PMID: 27507939.
    View in: PubMed
  3. Kussman BD, Aasted CM, Yücel MA, Steele SC, Alexander ME, Boas DA, Borsook D, Becerra L. Capturing Pain in the Cortex during General Anesthesia: Near Infrared Spectroscopy Measures in Patients Undergoing Catheter Ablation of Arrhythmias. PLoS One. 2016; 11(7):e0158975. PMID: 27415436.
    View in: PubMed
  4. Hubbard CS, Becerra L, Heinz N, Ludwick A, Rasooly T, Wu R, Johnson A, Schechter NL, Borsook D, Nurko S. Abdominal Pain, the Adolescent and Altered Brain Structure and Function. PLoS One. 2016; 11(5):e0156545. PMID: 27244227.
    View in: PubMed
  5. Noseda R, Bernstein CA, Nir RR, Lee AJ, Fulton AB, Bertisch SM, Hovaguimian A, Cestari DM, Saavedra-Walker R, Borsook D, Doran BL, Buettner C, Burstein R. Migraine photophobia originating in cone-driven retinal pathways. Brain. 2016 Jul; 139(Pt 7):1971-86. PMID: 27190022.
    View in: PubMed
  6. George E, Elman I, Becerra L, Berg S, Borsook D. Pain in an era of armed conflicts: Prevention and treatment for warfighters and civilian casualties. Prog Neurobiol. 2016 Jun; 141:25-44. PMID: 27084355.
    View in: PubMed
  7. Becerra L, Aasted CM, Boas DA, George E, Yücel MA, Kussman BD, Kelsey P, Borsook D. Brain measures of nociception using near-infrared spectroscopy in patients undergoing routine screening colonoscopy. Pain. 2016 Apr; 157(4):840-8. PMID: 26645550.
    View in: PubMed
  8. Becerra L, Veggeberg R, Prescot A, Jensen JE, Renshaw P, Scrivani S, Spierings EL, Burstein R, Borsook D. A 'complex' of brain metabolites distinguish altered chemistry in the cingulate cortex of episodic migraine patients. Neuroimage Clin. 2016; 11:588-94. PMID: 27158591.
    View in: PubMed
  9. Asghar MS, Becerra L, Larsson HB, Borsook D, Ashina M. Calcitonin Gene-Related Peptide Modulates Heat Nociception in the Human Brain - An fMRI Study in Healthy Volunteers. PLoS One. 2016; 11(3):e0150334. PMID: 26990646.
    View in: PubMed
  10. Bukhari Q, Borsook D, Rudin M, Becerra L. Random Forest Segregation of Drug Responses May Define Regions of Biological Significance. Front Comput Neurosci. 2016; 10:21. PMID: 27014046.
    View in: PubMed
  11. Simons LE, Erpelding N, Hernandez JM, Serrano P, Zhang K, Lebel AA, Sethna NF, Berde CB, Prabhu SP, Becerra L, Borsook D. Fear and Reward Circuit Alterations in Pediatric CRPS. Front Hum Neurosci. 2015; 9:703. PMID: 26834606.
    View in: PubMed
  12. Elman I, Borsook D. Common Brain Mechanisms of Chronic Pain and Addiction. Neuron. 2016 Jan 6; 89(1):11-36. PMID: 26748087.
    View in: PubMed
  13. Becerra L, Schwartzman RJ, Kiefer RT, Rohr P, Moulton EA, Wallin D, Pendse G, Morris S, Borsook D. CNS Measures of Pain Responses Pre- and Post-Anesthetic Ketamine in a Patient with Complex Regional Pain Syndrome. Pain Med. 2015 Dec; 16(12):2368-85. PMID: 26745152.
    View in: PubMed
  14. Faria V, Erpelding N, Lebel A, Johnson A, Wolff R, Fair D, Burstein R, Becerra L, Borsook D. The migraine brain in transition: girls vs boys. Pain. 2015 Nov; 156(11):2212-21. PMID: 26172552.
    View in: PubMed
  15. Becerra L, Bishop J, Barmettler G, Xie Y, Navratilova E, Porreca F, Borsook D. Triptans disrupt brain networks and promote stress-induced CSD-like responses in cortical and subcortical areas. J Neurophysiol. 2016 Jan 1; 115(1):208-17. PMID: 26490291.
    View in: PubMed
  16. Hodkinson DJ, Veggeberg R, Wilcox SL, Scrivani S, Burstein R, Becerra L, Borsook D. Primary Somatosensory Cortices Contain Altered Patterns of Regional Cerebral Blood Flow in the Interictal Phase of Migraine. PLoS One. 2015; 10(9):e0137971. PMID: 26372461; PMCID: PMC4570777.
  17. Yücel MA, Selb J, Aasted CM, Petkov MP, Becerra L, Borsook D, Boas DA. Short separation regression improves statistical significance and better localizes the hemodynamic response obtained by near-infrared spectroscopy for tasks with differing autonomic responses. Neurophotonics. 2015 Jul; 2(3):035005. PMID: 26835480.
    View in: PubMed
  18. Barakat N, Gorman MP, Benson L, Becerra L, Borsook D. Pain and spinal cord imaging measures in children with demyelinating disease. Neuroimage Clin. 2015; 9:338-47. PMID: 26509120; PMCID: PMC4588416.
  19. Simons LE, Smith A, Ibagon C, Coakley R, Logan DE, Schechter N, Borsook D, Hill JC. Pediatric Pain Screening Tool: rapid identification of risk in youth with pain complaints. Pain. 2015 Aug; 156(8):1511-8. PMID: 25906349; PMCID: PMC4504741 [Available on 08/01/16].
  20. Gilligan CJ, Borsook D. The Promise of Effective Pain Treatment Outcomes: Rallying Academic Centers to Lead the Charge. Pain Med. 2015 Aug; 16(8):1457-66. PMID: 26219090.
    View in: PubMed
  21. Maleki N, Barmettler G, Moulton EA, Scrivani S, Veggeberg R, Spierings EL, Burstein R, Becerra L, Borsook D. Female migraineurs show lack of insular thinning with age. Pain. 2015 Jul; 156(7):1232-9. PMID: 25775358; PMCID: PMC4474740 [Available on 07/01/16].
  22. Upadhyay J, Lemme J, Anderson J, Bleakman D, Large T, Evelhoch JL, Hargreaves R, Borsook D, Becerra L. Test-retest reliability of evoked heat stimulation BOLD fMRI. J Neurosci Methods. 2015 Sep 30; 253:38-46. PMID: 26072245.
    View in: PubMed
  23. Borsook D, Kussman B, George E, Becerra L, Burke D. Reply to Letter: "Surgically Induced Neuropathic Pain: Understanding the Perioperative Process". Ann Surg. 2015 Jun; 261(6):e162-3. PMID: 24299687.
    View in: PubMed
  24. Aasted CM, Yücel MA, Cooper RJ, Dubb J, Tsuzuki D, Becerra L, Petkov MP, Borsook D, Dan I, Boas DA. Anatomical guidance for functional near-infrared spectroscopy: AtlasViewer tutorial. Neurophotonics. 2015 Apr; 2(2):020801. PMID: 26157991; PMCID: PMC4478785 [Available on 04/01/16].
  25. Rosenthal P, Borsook D. Ocular neuropathic pain. Br J Ophthalmol. 2016 Jan; 100(1):128-34. PMID: 25943558.
    View in: PubMed
  26. Burstein R, Noseda R, Borsook D. Migraine: multiple processes, complex pathophysiology. J Neurosci. 2015 Apr 29; 35(17):6619-29. PMID: 25926442; PMCID: PMC4412887.
  27. Yücel MA, Aasted CM, Petkov MP, Borsook D, Boas DA, Becerra L. Specificity of hemodynamic brain responses to painful stimuli: a functional near-infrared spectroscopy study. Sci Rep. 2015; 5:9469. PMID: 25820289; PMCID: PMC4377554.
  28. Aggarwal S, Kheirkhah A, Cavalcanti BM, Cruzat A, Colon C, Brown E, Borsook D, Prüss H, Hamrah P. Autologous Serum Tears for Treatment of Photoallodynia in Patients with Corneal Neuropathy: Efficacy and Evaluation with In Vivo Confocal Microscopy. Ocul Surf. 2015 Jul; 13(3):250-62. PMID: 26045233; PMCID: PMC4499014 [Available on 07/01/16].
  29. Erpelding N, Simons L, Lebel A, Serrano P, Pielech M, Prabhu S, Becerra L, Borsook D. Rapid treatment-induced brain changes in pediatric CRPS. Brain Struct Funct. 2016 Mar; 221(2):1095-111. PMID: 25515312.
    View in: PubMed
  30. Schreiber KL, Campbell C, Martel MO, Greenbaum S, Wasan AD, Borsook D, Jamison RN, Edwards RR. Distraction analgesia in chronic pain patients: the impact of catastrophizing. Anesthesiology. 2014 Dec; 121(6):1292-301. PMID: 25264596.
    View in: PubMed
  31. Rojas-Mirquez JC, Rodriguez-Zuñiga MJ, Bonilla-Escobar FJ, Garcia-Perdomo HA, Petkov M, Becerra L, Borsook D, Linnman C. Nocebo effect in randomized clinical trials of antidepressants in children and adolescents: systematic review and meta-analysis. Front Behav Neurosci. 2014; 8:375. PMID: 25404901; PMCID: PMC4217505.
  32. Borsook D. The role of imaging. J Peripher Nerv Syst. 2014 Oct; 19 Suppl 2:S26-7. PMID: 25269738.
    View in: PubMed
  33. Barmettler G, Brawn J, Maleki N, Scrivani S, Burstein R, Becerra L, Borsook D. A new electronic diary tool for mapping and tracking spatial and temporal head pain patterns in migraine. Cephalalgia. 2015 Apr; 35(5):417-25. PMID: 25143550.
    View in: PubMed
  34. Borsook D, Hargreaves R, Bountra C, Porreca F. Lost but making progress--Where will new analgesic drugs come from? Sci Transl Med. 2014 Aug 13; 6(249):249sr3. PMID: 25122640; PMCID: PMC4319979.
  35. Becerra L, Sava S, Simons LE, Drosos AM, Sethna N, Berde C, Lebel AA, Borsook D. Intrinsic brain networks normalize with treatment in pediatric complex regional pain syndrome. Neuroimage Clin. 2014; 6:347-69. PMID: 25379449; PMCID: PMC4218937.
  36. Noseda R, Kainz V, Borsook D, Burstein R. Neurochemical pathways that converge on thalamic trigeminovascular neurons: potential substrate for modulation of migraine by sleep, food intake, stress and anxiety. PLoS One. 2014; 9(8):e103929. PMID: 25090640; PMCID: PMC4121288.
  37. Faria V, Linnman C, Lebel A, Borsook D. Harnessing the placebo effect in pediatric migraine clinic. J Pediatr. 2014 Oct; 165(4):659-65. PMID: 25063720; PMCID: PMC4358740.
  38. Xie JY, Qu C, Patwardhan A, Ossipov MH, Navratilova E, Becerra L, Borsook D, Porreca F. Activation of mesocorticolimbic reward circuits for assessment of relief of ongoing pain: a potential biomarker of efficacy. Pain. 2014 Aug; 155(8):1659-66. PMID: 24861580; PMCID: PMC4118589.
  39. Simons LE, Pielech M, Erpelding N, Linnman C, Moulton E, Sava S, Lebel A, Serrano P, Sethna N, Berde C, Becerra L, Borsook D. The responsive amygdala: treatment-induced alterations in functional connectivity in pediatric complex regional pain syndrome. Pain. 2014 Sep; 155(9):1727-42. PMID: 24861582; PMCID: PMC4157948.
  40. Moulton EA, Elman I, Becerra LR, Goldstein RZ, Borsook D. The cerebellum and addiction: insights gained from neuroimaging research. Addict Biol. 2014 May; 19(3):317-31. PMID: 24851284; PMCID: PMC4031616.
  41. Moulton EA, Becerra L, Johnson A, Burstein R, Borsook D. Altered hypothalamic functional connectivity with autonomic circuits and the locus coeruleus in migraine. PLoS One. 2014; 9(4):e95508. PMID: 24743801; PMCID: PMC3990690.
  42. Borsook D, Erpelding N, Lebel A, Linnman C, Veggeberg R, Grant PE, Buettner C, Becerra L, Burstein R. Sex and the migraine brain. Neurobiol Dis. 2014 Aug; 68:200-14. PMID: 24662368; PMCID: PMC4171725.
  43. Monteith TS, Borsook D. Insights and advances in post-traumatic headache: research considerations. Curr Neurol Neurosci Rep. 2014 Feb; 14(2):428. PMID: 24435590.
    View in: PubMed
  44. Simons LE, Elman I, Borsook D. Psychological processing in chronic pain: a neural systems approach. Neurosci Biobehav Rev. 2014 Feb; 39:61-78. PMID: 24374383; PMCID: PMC3944001.
  45. Taveira TH, Wu WC, Tschibelu E, Borsook D, Simonson DC, Yamamoto R, Langleben DD, Swift R, Elman I. The effect of naltrexone on body fat mass in olanzapine-treated schizophrenic or schizoaffective patients: a randomized double-blind placebo-controlled pilot study. J Psychopharmacol. 2014 Apr; 28(4):395-400. PMID: 24218048.
    View in: PubMed
  46. Borsook D, Erpelding N, Becerra L. Losses and gains: chronic pain and altered brain morphology. Expert Rev Neurother. 2013 Nov; 13(11):1221-34. PMID: 24164053.
    View in: PubMed
  47. Linnman C, Borsook D. Completing the Pain Circuit: Recent Advances in Imaging Pain and Inflammation beyond the Central Nervous System. Rambam Maimonides Med J. 2013; 4(4):e0026. PMID: 24228169; PMCID: PMC3820299.
  48. Erpelding N, Sava S, Simons LE, Lebel A, Serrano P, Becerra L, Borsook D. Habenula functional resting-state connectivity in pediatric CRPS. J Neurophysiol. 2014 Jan; 111(2):239-47. PMID: 24155006; PMCID: PMC3921385.
  49. Borsook D, Aasted CM, Burstein R, Becerra L. Migraine Mistakes: Error Awareness. Neuroscientist. 2014 Jun; 20(3):291-304. PMID: 24047609.
    View in: PubMed
  50. Erpelding N, Borsook D. Capturing brain metrics of neuropathic pain using nuclear magnetic resonance. Pain Manag. 2013 Sep; 3(5):395-409. PMID: 24654873.
    View in: PubMed
  51. Borsook D, Becerra L, Fava M. Use of functional imaging across clinical phases in CNS drug development. Transl Psychiatry. 2013; 3:e282. PMID: 23860483; PMCID: PMC3731782.
  52. Elman I, Borsook D, Volkow ND. Pain and suicidality: insights from reward and addiction neuroscience. Prog Neurobiol. 2013 Oct; 109:1-27. PMID: 23827972.
    View in: PubMed
  53. Becerra L, Navratilova E, Porreca F, Borsook D. Analogous responses in the nucleus accumbens and cingulate cortex to pain onset (aversion) and offset (relief) in rats and humans. J Neurophysiol. 2013 Sep; 110(5):1221-6. PMID: 23785130; PMCID: PMC3763092.
  54. Borsook D. Objectifying chronic pain: from the patient to diagnostic metrics. Virtual Mentor. 2013 May; 15(5):439-42. PMID: 23680566.
    View in: PubMed
  55. Linnman C, Becerra L, Lebel A, Berde C, Grant PE, Borsook D. Transient and persistent pain induced connectivity alterations in pediatric complex regional pain syndrome. PLoS One. 2013; 8(3):e57205. PMID: 23526938; PMCID: PMC3602432.
  56. Borsook D, Kalso E. Transforming pain medicine: adapting to science and society. Eur J Pain. 2013 Sep; 17(8):1109-25. PMID: 23468059; PMCID: PMC3681852.
  57. Borsook D, Edwards R, Elman I, Becerra L, Levine J. Pain and analgesia: the value of salience circuits. Prog Neurobiol. 2013 May; 104:93-105. PMID: 23499729; PMCID: PMC3644802.
  58. Borsook D, Kussman BD, George E, Becerra LR, Burke DW. Surgically induced neuropathic pain: understanding the perioperative process. Ann Surg. 2013 Mar; 257(3):403-12. PMID: 23059501; PMCID: PMC3546123.
  59. Bruehl S, Apkarian AV, Ballantyne JC, Berger A, Borsook D, Chen WG, Farrar JT, Haythornthwaite JA, Horn SD, Iadarola MJ, Inturrisi CE, Lao L, Mackey S, Mao J, Sawczuk A, Uhl GR, Witter J, Woolf CJ, Zubieta JK, Lin Y. Personalized medicine and opioid analgesic prescribing for chronic pain: opportunities and challenges. J Pain. 2013 Feb; 14(2):103-13. PMID: 23374939; PMCID: PMC3564046.
  60. Becerra L, Upadhyay J, Chang PC, Bishop J, Anderson J, Baumgartner R, Schwarz AJ, Coimbra A, Wallin D, Nutile L, George E, Maier G, Sunkaraneni S, Iyengar S, Evelhoch JL, Bleakman D, Hargreaves R, Borsook D. Parallel buprenorphine phMRI responses in conscious rodents and healthy human subjects. J Pharmacol Exp Ther. 2013 Apr; 345(1):41-51. PMID: 23370795.
    View in: PubMed
  61. Maleki N, Brawn J, Barmettler G, Borsook D, Becerra L. Pain response measured with arterial spin labeling. NMR Biomed. 2013 Jun; 26(6):664-73. PMID: 23319440; PMCID: PMC3634868.
  62. Gear R, Becerra L, Upadhyay J, Bishop J, Wallin D, Pendse G, Levine J, Borsook D. Pain facilitation brain regions activated by nalbuphine are revealed by pharmacological fMRI. PLoS One. 2013; 8(1):e50169. PMID: 23341872; PMCID: PMC3540048.
  63. Linnman C, Becerra L, Borsook D. Inflaming the brain: CRPS a model disease to understand neuroimmune interactions in chronic pain. J Neuroimmune Pharmacol. 2013 Jun; 8(3):547-63. PMID: 23188523; PMCID: PMC3596443.
  64. Linnman C, Maleki N, Becerra L, Borsook D. Migraine tweets - what can online behavior tell us about disease? Cephalalgia. 2013 Jan; 33(1):68-9. PMID: 23136208; PMCID: PMC3808841.
  65. Simons LE, Moulton EA, Linnman C, Carpino E, Becerra L, Borsook D. The human amygdala and pain: evidence from neuroimaging. Hum Brain Mapp. 2014 Feb; 35(2):527-38. PMID: 23097300; PMCID: PMC3920543.
  66. Maleki N, Becerra L, Borsook D. Migraine: maladaptive brain responses to stress. Headache. 2012 Oct; 52 Suppl 2:102-6. PMID: 23030541; PMCID: PMC3475609.
  67. Moulton EA, Becerra L, Rosenthal P, Borsook D. An approach to localizing corneal pain representation in human primary somatosensory cortex. PLoS One. 2012; 7(9):e44643. PMID: 22973463; PMCID: PMC3433421.
  68. Maleki N, Linnman C, Brawn J, Burstein R, Becerra L, Borsook D. Her versus his migraine: multiple sex differences in brain function and structure. Brain. 2012 Aug; 135(Pt 8):2546-59. PMID: 22843414; PMCID: PMC3407427.
  69. Borsook D, Burstein R. The enigma of the dorsolateral pons as a migraine generator. Cephalalgia. 2012 Aug; 32(11):803-12. PMID: 22798640; PMCID: PMC3711518.
  70. Maleki N, Becerra L, Brawn J, McEwen B, Burstein R, Borsook D. Common hippocampal structural and functional changes in migraine. Brain Struct Funct. 2013 Jul; 218(4):903-12. PMID: 22760159; PMCID: PMC3711530.
  71. Borsook D. A future without chronic pain: neuroscience and clinical research. Cerebrum. 2012 May; 2012:7. PMID: 23447793; PMCID: PMC3574803.
  72. Kurbanov DB, Currie PJ, Simonson DC, Borsook D, Elman I. Effects of naltrexone on food intake and body weight gain in olanzapine-treated rats. J Psychopharmacol. 2012 Sep; 26(9):1244-51. PMID: 22723540.
    View in: PubMed
  73. Sprenger T, Borsook D. Migraine changes the brain: neuroimaging makes its mark. Curr Opin Neurol. 2012 Jun; 25(3):252-62. PMID: 22487570; PMCID: PMC3380341.
  74. Maleki N, Becerra L, Brawn J, Bigal M, Burstein R, Borsook D. Concurrent functional and structural cortical alterations in migraine. Cephalalgia. 2012 Jun; 32(8):607-20. PMID: 22623760; PMCID: PMC3846436.
  75. Borsook D, Upadhyay J, Klimas M, Schwarz AJ, Coimbra A, Baumgartner R, George E, Potter WZ, Large T, Bleakman D, Evelhoch J, Iyengar S, Becerra L, Hargreaves RJ. Decision-making using fMRI in clinical drug development: revisiting NK-1 receptor antagonists for pain. Drug Discov Today. 2012 Sep; 17(17-18):964-73. PMID: 22579743.
    View in: PubMed
  76. Moulton EA, Pendse G, Becerra LR, Borsook D. BOLD responses in somatosensory cortices better reflect heat sensation than pain. J Neurosci. 2012 Apr 25; 32(17):6024-31. PMID: 22539862; PMCID: PMC3347471.
  77. Toledo E, Lebel A, Becerra L, Minster A, Linnman C, Maleki N, Dodick DW, Borsook D. The young brain and concussion: imaging as a biomarker for diagnosis and prognosis. Neurosci Biobehav Rev. 2012 Jul; 36(6):1510-31. PMID: 22476089; PMCID: PMC3372677.
  78. Borsook D. 'Hot feet - hot brain': gene and brain dysfunction in erythromelalgia. Pain. 2012 May; 153(5):945-7. PMID: 22405816.
    View in: PubMed
  79. Shelton L, Pendse G, Maleki N, Moulton EA, Lebel A, Becerra L, Borsook D. Mapping pain activation and connectivity of the human habenula. J Neurophysiol. 2012 May; 107(10):2633-48. PMID: 22323632; PMCID: PMC3362277.
  80. Elman I, Becerra L, Tschibelu E, Yamamoto R, George E, Borsook D. Yohimbine-induced amygdala activation in pathological gamblers: a pilot study. PLoS One. 2012; 7(2):e31118. PMID: 22319607; PMCID: PMC3271103.
  81. Borsook D, Maleki N, Becerra L, McEwen B. Understanding migraine through the lens of maladaptive stress responses: a model disease of allostatic load. Neuron. 2012 Jan 26; 73(2):219-34. PMID: 22284178.
    View in: PubMed
  82. Shelton L, Becerra L, Borsook D. Unmasking the mysteries of the habenula in pain and analgesia. Prog Neurobiol. 2012 Feb; 96(2):208-19. PMID: 22270045; PMCID: PMC3465722.
  83. Rosenthal P, Borsook D. The corneal pain system. Part I: the missing piece of the dry eye puzzle. Ocul Surf. 2012 Jan; 10(1):2-14. PMID: 22330055.
    View in: PubMed
  84. Linnman C, Moulton EA, Barmettler G, Becerra L, Borsook D. Neuroimaging of the periaqueductal gray: state of the field. Neuroimage. 2012 Mar; 60(1):505-22. PMID: 22197740; PMCID: PMC3288184.
  85. Pendse GV, Borsook D, Becerra L. A simple and objective method for reproducible resting state network (RSN) detection in fMRI. PLoS One. 2011; 6(12):e27594. PMID: 22174743; PMCID: PMC3236249.
  86. Upadhyay J, Anderson J, Baumgartner R, Coimbra A, Schwarz AJ, Pendse G, Wallin D, Nutile L, Bishop J, George E, Elman I, Sunkaraneni S, Maier G, Iyengar S, Evelhoch JL, Bleakman D, Hargreaves R, Becerra L, Borsook D. Modulation of CNS pain circuitry by intravenous and sublingual doses of buprenorphine. Neuroimage. 2012 Feb 15; 59(4):3762-73. PMID: 22119647.
    View in: PubMed
  87. Borsook D. Neurological diseases and pain. Brain. 2012 Feb; 135(Pt 2):320-44. PMID: 22067541; PMCID: PMC3281476.
  88. Becerra L, Pendse G, Chang PC, Bishop J, Borsook D. Robust reproducible resting state networks in the awake rodent brain. PLoS One. 2011; 6(10):e25701. PMID: 22028788; PMCID: PMC3196498.
  89. Noseda R, Jakubowski M, Kainz V, Borsook D, Burstein R. Cortical projections of functionally identified thalamic trigeminovascular neurons: implications for migraine headache and its associated symptoms. J Neurosci. 2011 Oct 5; 31(40):14204-17. PMID: 21976505; PMCID: PMC3501387.
  90. Maleki N, Becerra L, Nutile L, Pendse G, Brawn J, Bigal M, Burstein R, Borsook D. Migraine attacks the Basal Ganglia. Mol Pain. 2011; 7:71. PMID: 21936901; PMCID: PMC3192678.
  91. Upadhyay J, Anderson J, Schwarz AJ, Coimbra A, Baumgartner R, Pendse G, George E, Nutile L, Wallin D, Bishop J, Neni S, Maier G, Iyengar S, Evelhoch JL, Bleakman D, Hargreaves R, Becerra L, Borsook D. Imaging drugs with and without clinical analgesic efficacy. Neuropsychopharmacology. 2011 Dec; 36(13):2659-73. PMID: 21849979; PMCID: PMC3230490.
  92. Borsook D, Rosenthal P. Chronic (neuropathic) corneal pain and blepharospasm: five case reports. Pain. 2011 Oct; 152(10):2427-31. PMID: 21752546.
    View in: PubMed
  93. Borsook D, Becerra L. How close are we in utilizing functional neuroimaging in routine clinical diagnosis of neuropathic pain? Curr Pain Headache Rep. 2011 Jun; 15(3):223-9. PMID: 21369853.
    View in: PubMed
  94. Schwarz AJ, Becerra L, Upadhyay J, Anderson J, Baumgartner R, Coimbra A, Evelhoch J, Hargreaves R, Robertson B, Iyengar S, Tauscher J, Bleakman D, Borsook D. A procedural framework for good imaging practice in pharmacological fMRI studies applied to drug development #1: processes and requirements. Drug Discov Today. 2011 Jul; 16(13-14):583-93. PMID: 21635967.
    View in: PubMed
  95. Schwarz AJ, Becerra L, Upadhyay J, Anderson J, Baumgartner R, Coimbra A, Evelhoch J, Hargreaves R, Robertson B, Iyengar S, Tauscher J, Bleakman D, Borsook D. A procedural framework for good imaging practice in pharmacological fMRI studies applied to drug development #2: protocol optimization and best practices. Drug Discov Today. 2011 Aug; 16(15-16):671-82. PMID: 21477664.
    View in: PubMed
  96. Moulton EA, Elman I, Pendse G, Schmahmann J, Becerra L, Borsook D. Aversion-related circuitry in the cerebellum: responses to noxious heat and unpleasant images. J Neurosci. 2011 Mar 9; 31(10):3795-804. PMID: 21389234; PMCID: PMC3063442.
  97. Borsook D, Becerra L, Hargreaves R. Biomarkers for chronic pain and analgesia. Part 1: the need, reality, challenges, and solutions. Discov Med. 2011 Mar; 11(58):197-207. PMID: 21447279.
    View in: PubMed
  98. Borsook D, Becerra L, Hargreaves R. Biomarkers for chronic pain and analgesia. Part 2: how, where, and what to look for using functional imaging. Discov Med. 2011 Mar; 11(58):209-19. PMID: 21447280.
    View in: PubMed
  99. Maleki N, Becerra L, Upadhyay J, Burstein R, Borsook D. Direct optic nerve pulvinar connections defined by diffusion MR tractography in humans: implications for photophobia. Hum Brain Mapp. 2012 Jan; 33(1):75-88. PMID: 21337474; PMCID: PMC3711521.
  100. Elman I, Zubieta JK, Borsook D. The missing p in psychiatric training: why it is important to teach pain to psychiatrists. Arch Gen Psychiatry. 2011 Jan; 68(1):12-20. PMID: 21199962; PMCID: PMC3085192.
  101. Borsook D, Becerra L. CNS animal fMRI in pain and analgesia. Neurosci Biobehav Rev. 2011 Apr; 35(5):1125-43. PMID: 21126534; PMCID: PMC3076623.
  102. Borsook D, Hargreaves R. Brain imaging in migraine research. Headache. 2010 Oct; 50(9):1523-7. PMID: 20958298.
    View in: PubMed
  103. Becerra L, Chang PC, Bishop J, Borsook D. CNS activation maps in awake rats exposed to thermal stimuli to the dorsum of the hindpaw. Neuroimage. 2011 Jan 15; 54(2):1355-66. PMID: 20817102.
    View in: PubMed
  104. Borsook D, George E, Kussman B, Becerra L. Anesthesia and perioperative stress: consequences on neural networks and postoperative behaviors. Prog Neurobiol. 2010 Dec; 92(4):601-12. PMID: 20727935.
    View in: PubMed
  105. Borsook D, Becerra L. Using NMR approaches to drive the search for new CNS therapeutics. Curr Opin Investig Drugs. 2010 Jul; 11(7):771-8. PMID: 20571972; PMCID: PMC3010855.
  106. Burstein R, Jakubowski M, Garcia-Nicas E, Kainz V, Bajwa Z, Hargreaves R, Becerra L, Borsook D. Thalamic sensitization transforms localized pain into widespread allodynia. Ann Neurol. 2010 Jul; 68(1):81-91. PMID: 20582997; PMCID: PMC2930514.
  107. Elman I, Tschibelu E, Borsook D. Psychosocial stress and its relationship to gambling urges in individuals with pathological gambling. Am J Addict. 2010 Jul-Aug; 19(4):332-9. PMID: 20653640.
    View in: PubMed
  108. Moulton EA, Becerra L, Maleki N, Pendse G, Tully S, Hargreaves R, Burstein R, Borsook D. Painful heat reveals hyperexcitability of the temporal pole in interictal and ictal migraine States. Cereb Cortex. 2011 Feb; 21(2):435-48. PMID: 20562317; PMCID: PMC3020583.
  109. Upadhyay J, Maleki N, Potter J, Elman I, Rudrauf D, Knudsen J, Wallin D, Pendse G, McDonald L, Griffin M, Anderson J, Nutile L, Renshaw P, Weiss R, Becerra L, Borsook D. Alterations in brain structure and functional connectivity in prescription opioid-dependent patients. Brain. 2010 Jul; 133(Pt 7):2098-114. PMID: 20558415; PMCID: PMC2912691.
  110. Pendse GV, Schwarz AJ, Baumgartner R, Coimbra A, Upadhyay J, Borsook D, Becerra L. Robust, unbiased general linear model estimation of phMRI signal amplitude in the presence of variation in the temporal response profile. J Magn Reson Imaging. 2010 Jun; 31(6):1445-57. PMID: 20512898.
    View in: PubMed
  111. George E, Becerra L, Upadhyay J, Schmidt U, Borsook D. Evaluation of novel drugs using fMRI in early-phase clinical trials: safety monitoring. Drug Discov Today. 2010 Aug; 15(15-16):684-9. PMID: 20553959; PMCID: PMC2921954.
  112. Moulton EA, Schmahmann JD, Becerra L, Borsook D. The cerebellum and pain: passive integrator or active participator? Brain Res Rev. 2010 Oct 5; 65(1):14-27. PMID: 20553761; PMCID: PMC2943015.
  113. Borsook D, Upadhyay J, Chudler EH, Becerra L. A key role of the basal ganglia in pain and analgesia--insights gained through human functional imaging. Mol Pain. 2010; 6:27. PMID: 20465845; PMCID: PMC2883978.
  114. Scrivani S, Wallin D, Moulton EA, Cole S, Wasan AD, Lockerman L, Bajwa Z, Upadhyay J, Becerra L, Borsook D. A fMRI evaluation of lamotrigine for the treatment of trigeminal neuropathic pain: pilot study. Pain Med. 2010 Jun; 11(6):920-41. PMID: 20492571.
    View in: PubMed
  115. Borsook D, Sava S, Becerra L. The pain imaging revolution: advancing pain into the 21st century. Neuroscientist. 2010 Apr; 16(2):171-85. PMID: 20400714; PMCID: PMC3370428.
  116. Pendse GV, Baumgartner R, Schwarz AJ, Coimbra A, Borsook D, Becerra L. A statistical framework for optimal design matrix generation with application to fMRI. IEEE Trans Med Imaging. 2010 Sep; 29(9):1573-611. PMID: 20304726.
    View in: PubMed
  117. Becerra L, Harris W, Grant M, George E, Boas D, Borsook D. Diffuse optical tomography activation in the somatosensory cortex: specific activation by painful vs. non-painful thermal stimuli. PLoS One. 2009; 4(11):e8016. PMID: 19956637; PMCID: PMC2778627.
  118. Upadhyay J, Pendse G, Anderson J, Schwarz AJ, Baumgartner R, Coimbra A, Bishop J, Knudsen J, George E, Grachev I, Iyengar S, Bleakman D, Hargreaves R, Borsook D, Becerra L. Improved characterization of BOLD responses for evoked sensory stimuli. Neuroimage. 2010 Feb 1; 49(3):2275-86. PMID: 19854280.
    View in: PubMed
  119. Moulton EA, Becerra L, Borsook D. An fMRI case report of photophobia: activation of the trigeminal nociceptive pathway. Pain. 2009 Oct; 145(3):358-63. PMID: 19674842; PMCID: PMC2756998.
  120. Borsook D. Ketamine and chronic pain--going the distance. Pain. 2009 Oct; 145(3):271-2. PMID: 19573988; PMCID: PMC2875542.
  121. Prescot A, Becerra L, Pendse G, Tully S, Jensen E, Hargreaves R, Renshaw P, Burstein R, Borsook D. Excitatory neurotransmitters in brain regions in interictal migraine patients. Mol Pain. 2009; 5:34. PMID: 19566960; PMCID: PMC2714306.
  122. Sava S, Lebel AA, Leslie DS, Drosos A, Berde C, Becerra L, Borsook D. Challenges of functional imaging research of pain in children. Mol Pain. 2009; 5:30. PMID: 19531255; PMCID: PMC2702328.
  123. Borsook D, Sava S. Pain: Do ACE inhibitors exacerbate complex regional pain syndrome? Nat Rev Neurol. 2009 Jun; 5(6):306-8. PMID: 19498433.
    View in: PubMed
  124. Pendse G, Borsook D, Becerra L. Enhanced false discovery rate using Gaussian mixture models for thresholding fMRI statistical maps. Neuroimage. 2009 Aug 1; 47(1):231-61. PMID: 19269334; PMCID: PMC2735129.
  125. Moulton EA, Pendse G, Morris S, Aiello-Lammens M, Becerra L, Borsook D. Segmentally arranged somatotopy within the face representation of human primary somatosensory cortex. Hum Brain Mapp. 2009 Mar; 30(3):757-65. PMID: 18266215.
    View in: PubMed
  126. Borsook D, Becerra L. Emotional pain without sensory pain--dream on? Neuron. 2009 Jan 29; 61(2):153-5. PMID: 19186157.
    View in: PubMed
  127. Moulton EA, Burstein R, Tully S, Hargreaves R, Becerra L, Borsook D. Interictal dysfunction of a brainstem descending modulatory center in migraine patients. PLoS One. 2008; 3(11):e3799. PMID: 19030105; PMCID: PMC2582961.
  128. Upadhyay J, Knudsen J, Anderson J, Becerra L, Borsook D. Noninvasive mapping of human trigeminal brainstem pathways. Magn Reson Med. 2008 Nov; 60(5):1037-46. PMID: 18956455; PMCID: PMC2597480.
  129. DaSilva AF, Becerra L, Pendse G, Chizh B, Tully S, Borsook D. Colocalized structural and functional changes in the cortex of patients with trigeminal neuropathic pain. PLoS One. 2008; 3(10):e3396. PMID: 18923647; PMCID: PMC2561059.
  130. Bieber CM, Fernandez K, Borsook D, Brennan MJ, Butler SF, Jamison RN, Osgood E, Sharpe-Potter J, Thomson HN, Weiss RD, Katz NP. Retrospective accounts of initial subjective effects of opioids in patients treated for pain who do or do not develop opioid addiction: a pilot case-control study. Exp Clin Psychopharmacol. 2008 Oct; 16(5):429-34. PMID: 18837639; PMCID: PMC3153468.
  131. Lebel A, Becerra L, Wallin D, Moulton EA, Morris S, Pendse G, Jasciewicz J, Stein M, Aiello-Lammens M, Grant E, Berde C, Borsook D. fMRI reveals distinct CNS processing during symptomatic and recovered complex regional pain syndrome in children. Brain. 2008 Jul; 131(Pt 7):1854-79. PMID: 18567621.
    View in: PubMed
  132. Borsook D, Bleakman D, Hargreaves R, Upadhyay J, Schmidt KF, Becerra L. A 'BOLD' experiment in defining the utility of fMRI in drug development. Neuroimage. 2008 Aug 15; 42(2):461-6. PMID: 18598770.
    View in: PubMed
  133. Becerra L, Harris W, Joseph D, Huppert T, Boas DA, Borsook D. Diffuse optical tomography of pain and tactile stimulation: activation in cortical sensory and emotional systems. Neuroimage. 2008 Jun; 41(2):252-9. PMID: 18394924; PMCID: PMC2728450.
  134. Becerra L, Borsook D. Signal valence in the nucleus accumbens to pain onset and offset. Eur J Pain. 2008 Oct; 12(7):866-9. PMID: 18226937; PMCID: PMC2581873.
  135. Borsook D, Moulton EA, Tully S, Schmahmann JD, Becerra L. Human cerebellar responses to brush and heat stimuli in healthy and neuropathic pain subjects. Cerebellum. 2008; 7(3):252-72. PMID: 18418691.
    View in: PubMed
  136. Grant PE, Gallagher J, Gonzalez RG, Borsook D. Adriamycin injection into the medial cord of the brachial plexus: computed tomography-guided targeted pain therapy. Pain Med. 2008 Jan-Feb; 9(1):83-7. PMID: 18254771.
    View in: PubMed
  137. Borsook D, Moulton EA, Pendse G, Morris S, Cole SH, Aiello-Lammens M, Scrivani S, Becerra LR. Comparison of evoked vs. spontaneous tics in a patient with trigeminal neuralgia (tic doloureux). Mol Pain. 2007; 3:34. PMID: 17983481; PMCID: PMC2217520.
  138. Borsook D. Pain and motor system plasticity. Pain. 2007 Nov; 132(1-2):8-9. PMID: 17892913; PMCID: PMC2701107.
  139. Borsook D, Moulton EA, Schmidt KF, Becerra LR. Neuroimaging revolutionizes therapeutic approaches to chronic pain. Mol Pain. 2007; 3:25. PMID: 17848191; PMCID: PMC2048498.
  140. Borsook D, Becerra L. Phenotyping central nervous system circuitry in chronic pain using functional MRI: considerations and potential implications in the clinic. Curr Pain Headache Rep. 2007 Jun; 11(3):201-7. PMID: 17504647.
    View in: PubMed
  141. DaSilva AF, Goadsby PJ, Borsook D. Cluster headache: a review of neuroimaging findings. Curr Pain Headache Rep. 2007 Apr; 11(2):131-6. PMID: 17367592.
    View in: PubMed
  142. Moulton EA, Pendse G, Morris S, Strassman A, Aiello-Lammens M, Becerra L, Borsook D. Capsaicin-induced thermal hyperalgesia and sensitization in the human trigeminal nociceptive pathway: an fMRI study. Neuroimage. 2007 May 1; 35(4):1586-600. PMID: 17407825; PMCID: PMC2034350.
  143. Becerra L, Morris S, Bazes S, Gostic R, Sherman S, Gostic J, Pendse G, Moulton E, Scrivani S, Keith D, Chizh B, Borsook D. Trigeminal neuropathic pain alters responses in CNS circuits to mechanical (brush) and thermal (cold and heat) stimuli. J Neurosci. 2006 Oct 18; 26(42):10646-57. PMID: 17050704.
    View in: PubMed
  144. Borsook D, Becerra LR. Breaking down the barriers: fMRI applications in pain, analgesia and analgesics. Mol Pain. 2006; 2:30. PMID: 16982005; PMCID: PMC1592305.
  145. Becerra L, Harter K, Gonzalez RG, Borsook D. Functional magnetic resonance imaging measures of the effects of morphine on central nervous system circuitry in opioid-naive healthy volunteers. Anesth Analg. 2006 Jul; 103(1):208-16, table of contents. PMID: 16790655.
    View in: PubMed
  146. Negus SS, Vanderah TW, Brandt MR, Bilsky EJ, Becerra L, Borsook D. Preclinical assessment of candidate analgesic drugs: recent advances and future challenges. J Pharmacol Exp Ther. 2006 Nov; 319(2):507-14. PMID: 16751251.
    View in: PubMed
  147. Borsook D, Burstein R, Moulton E, Becerra L. Functional imaging of the trigeminal system: applications to migraine pathophysiology. Headache. 2006 Jun; 46 Suppl 1:S32-8. PMID: 16927962.
    View in: PubMed
  148. Borsook D, Becerra L, Hargreaves R. A role for fMRI in optimizing CNS drug development. Nat Rev Drug Discov. 2006 May; 5(5):411-24. PMID: 16604100.
    View in: PubMed
  149. Elman I, Borsook D, Lukas SE. Food intake and reward mechanisms in patients with schizophrenia: implications for metabolic disturbances and treatment with second-generation antipsychotic agents. Neuropsychopharmacology. 2006 Oct; 31(10):2091-120. PMID: 16541087.
    View in: PubMed
  150. Borsook D, Becerra L, Carlezon WA, Shaw M, Renshaw P, Elman I, Levine J. Reward-aversion circuitry in analgesia and pain: implications for psychiatric disorders. Eur J Pain. 2007 Jan; 11(1):7-20. PMID: 16495096.
    View in: PubMed
  151. Aharon I, Becerra L, Becerraa L, Chabris CF, Borsook D, Borsooka D. Noxious heat induces fMRI activation in two anatomically distinct clusters within the nucleus accumbens. Neurosci Lett. 2006 Jan 16; 392(3):159-64. PMID: 16257488.
    View in: PubMed
  152. Borsook D, Becerra L. Functional imaging of pain and analgesia--a valid diagnostic tool? Pain. 2005 Oct; 117(3):247-50. PMID: 16154699.
    View in: PubMed
  153. Hama AT, Borsook D. The effect of antinociceptive drugs tested at different times after nerve injury in rats. Anesth Analg. 2005 Jul; 101(1):175-9, table of contents. PMID: 15976228.
    View in: PubMed
  154. Hama AT, Borsook D. Behavioral and pharmacological characterization of a distal peripheral nerve injury in the rat. Pharmacol Biochem Behav. 2005 May; 81(1):170-81. PMID: 15894076.
    View in: PubMed
  155. Borsook D, Burstein R, Becerra L. Functional imaging of the human trigeminal system: opportunities for new insights into pain processing in health and disease. J Neurobiol. 2004 Oct; 61(1):107-25. PMID: 15362156.
    View in: PubMed
  156. Borras MC, Becerra L, Ploghaus A, Gostic JM, DaSilva A, Gonzalez RG, Borsook D. fMRI measurement of CNS responses to naloxone infusion and subsequent mild noxious thermal stimuli in healthy volunteers. J Neurophysiol. 2004 Jun; 91(6):2723-33. PMID: 15136603.
    View in: PubMed
  157. Borsook D, Edwards AD. Antineuropathic effects of the antibiotic derivative spicamycin KRN5500. Pain Med. 2004 Mar; 5(1):104-8. PMID: 14996243.
    View in: PubMed
  158. Becerra L, Iadarola M, Borsook D. CNS activation by noxious heat to the hand or foot: site-dependent delay in sensory but not emotion circuitry. J Neurophysiol. 2004 Jan; 91(1):533-41. PMID: 14715722.
    View in: PubMed
  159. Borsook D, Becerra L. Pain imaging: future applications to integrative clinical and basic neurobiology. Adv Drug Deliv Rev. 2003 Aug 28; 55(8):967-86. PMID: 12935940.
    View in: PubMed
  160. Borsook D. Pain: the past, present and future. Adv Drug Deliv Rev. 2003 Aug 28; 55(8):931-4. PMID: 12935937.
    View in: PubMed
  161. Borsook D, DaSilva AF, Ploghaus A, Becerra L. Specific and somatotopic functional magnetic resonance imaging activation in the trigeminal ganglion by brush and noxious heat. J Neurosci. 2003 Aug 27; 23(21):7897-903. PMID: 12944520.
    View in: PubMed
  162. Kobierski LA, Abdi S, DiLorenzo L, Feroz N, Borsook D. A single intravenous injection of KRN5500 (antibiotic spicamycin) produces long-term decreases in multiple sensory hypersensitivities in neuropathic pain. Anesth Analg. 2003 Jul; 97(1):174-82, table of contents. PMID: 12818962.
    View in: PubMed
  163. Ploghaus A, Becerra L, Borras C, Borsook D. Neural circuitry underlying pain modulation: expectation, hypnosis, placebo. Trends Cogn Sci. 2003 May; 7(5):197-200. PMID: 12757820.
    View in: PubMed
  164. DaSilva AF, Becerra L, Makris N, Strassman AM, Gonzalez RG, Geatrakis N, Borsook D. Somatotopic activation in the human trigeminal pain pathway. J Neurosci. 2002 Sep 15; 22(18):8183-92. PMID: 12223572.
    View in: PubMed
  165. DiLorenzo L, Kobierski L, Moore KA, Borsook D. A water-soluble synthetic spicamycin derivative (San-Gly) decreases mechanical allodynia in a rodent model of neuropathic pain. Neurosci Lett. 2002 Sep 13; 330(1):37-40. PMID: 12213629.
    View in: PubMed
  166. Borsook D, Ploghaus A, Becerra L. Utilizing brain imaging for analgesic drug development. Curr Opin Investig Drugs. 2002 Sep; 3(9):1342-7. PMID: 12498011.
    View in: PubMed
  167. Becerra L, Breiter HC, Wise R, Gonzalez RG, Borsook D. Reward circuitry activation by noxious thermal stimuli. Neuron. 2001 Dec 6; 32(5):927-46. PMID: 11738036.
    View in: PubMed
  168. Fishman SM, Wilsey B, Yang J, Reisfield GM, Bandman TB, Borsook D. Adherence monitoring and drug surveillance in chronic opioid therapy. J Pain Symptom Manage. 2000 Oct; 20(4):293-307. PMID: 11027912.
    View in: PubMed
  169. Abdi S, Vilassova N, Decosterd I, Feroz N, Borsook D. The effects of KRN5500, a spicamycin derivative, on neuropathic and nociceptive pain models in rats. Anesth Analg. 2000 Oct; 91(4):955-9. PMID: 11004056.
    View in: PubMed
  170. Tracey I, Becerra L, Chang I, Breiter H, Jenkins L, Borsook D, González RG. Noxious hot and cold stimulation produce common patterns of brain activation in humans: a functional magnetic resonance imaging study. Neurosci Lett. 2000 Jul 14; 288(2):159-62. PMID: 10876085.
    View in: PubMed
  171. Kobierski LA, Srivastava S, Borsook D. Systemic lipopolysaccharide and interleukin-1beta activate the interleukin 6: STAT intracellular signaling pathway in neurons of mouse trigeminal ganglion. Neurosci Lett. 2000 Mar 3; 281(1):61-4. PMID: 10686416.
    View in: PubMed
  172. Kobierski LA, Wong AE, Srivastava S, Borsook D, Hyman SE. Cyclic AMP-dependent activation of the proenkephalin gene requires phosphorylation of CREB at serine-133 and a Src-related kinase. J Neurochem. 1999 Jul; 73(1):129-38. PMID: 10386963.
    View in: PubMed
  173. Fishman SM, Bandman TB, Edwards A, Borsook D. The opioid contract in the management of chronic pain. J Pain Symptom Manage. 1999 Jul; 18(1):27-37. PMID: 10439570.
    View in: PubMed
  174. Becerra LR, Breiter HC, Stojanovic M, Fishman S, Edwards A, Comite AR, Gonzalez RG, Borsook D. Human brain activation under controlled thermal stimulation and habituation to noxious heat: an fMRI study. Magn Reson Med. 1999 May; 41(5):1044-57. PMID: 10332889.
    View in: PubMed
  175. Van Koughnet K, Smirnova O, Hyman SE, Borsook D. Proenkephalin transgene regulation in the paraventricular nucleus of the hypothalamus by lipopolysaccharide and interleukin-1beta. J Comp Neurol. 1999 Mar 8; 405(2):199-215. PMID: 10023810.
    View in: PubMed
  176. Borsook D, Smirnova O, Behar O, Lewis S, Kobierski LA. PhosphoCREB and CREM/ICER: positive and negative regulation of proenkephalin gene expression in the paraventricular nucleus of the hypothalamus. J Mol Neurosci. 1999 Feb; 12(1):35-51. PMID: 10636469.
    View in: PubMed
  177. Fishman SM, Caneris OA, Bandman TB, Audette JF, Borsook D. Injection of the piriformis muscle by fluoroscopic and electromyographic guidance. Reg Anesth Pain Med. 1998 Nov-Dec; 23(6):554-9. PMID: 9840849.
    View in: PubMed
  178. Borsook D, Becerra L, Fishman S, Edwards A, Jennings CL, Stojanovic M, Papinicolas L, Ramachandran VS, Gonzalez RG, Breiter H. Acute plasticity in the human somatosensory cortex following amputation. Neuroreport. 1998 Apr 20; 9(6):1013-7. PMID: 9601659.
    View in: PubMed
  179. Borsook D, Falkowski O, Smirnova O. Proenkephalin gene regulation in the paraventricular nucleus by GABA: interactions with opioid systems in a transgenic model. J Neurochem. 1998 Feb; 70(2):604-16. PMID: 9453554.
    View in: PubMed
  180. Fishman SM, Caneris OA, Stojanovic MP, Borsook D. Intravenous lidocaine for treatment-resistant pruritus. Am J Med. 1997 Jun; 102(6):584-5. PMID: 9217675.
    View in: PubMed
  181. Priest CA, Borsook D, Pfaff DW. Estrogen and stress interact to regulate the hypothalamic expression of a human proenkephalin promoter-beta-galactosidase fusion gene in a site-specific and sex-specific manner. J Neuroendocrinol. 1997 Apr; 9(4):317-26. PMID: 9147295.
    View in: PubMed
  182. Manfredi PL, Borsook D, Chandler SW, Payne R. Intravenous methadone for cancer pain unrelieved by morphine and hydromorphone: clinical observations. Pain. 1997 Mar; 70(1):99-101. PMID: 9106815.
    View in: PubMed
  183. Fishman SM, Catarau EM, Sachs G, Stojanovic M, Borsook D. Corticosteroid-induced mania after single regional application at the celiac plexus. Anesthesiology. 1996 Nov; 85(5):1194-6. PMID: 8916839.
    View in: PubMed
  184. Burstein R, Falkowsky O, Borsook D, Strassman A. Distinct lateral and medial projections of the spinohypothalamic tract of the rat. J Comp Neurol. 1996 Sep 30; 373(4):549-74. PMID: 8889944.
    View in: PubMed
  185. Hyman SE, Borsook D. Mechanisms regulating proenkephalin gene expression: contributions of transgenic models. NIDA Res Monogr. 1996; 161:59-71. PMID: 8784844.
    View in: PubMed
  186. Borsook D, Hyman SE. Proenkephalin gene regulation in the neuroendocrine hypothalamus: a model of gene regulation in the CNS. Am J Physiol. 1995 Sep; 269(3 Pt 1):E393-408. PMID: 7573416.
    View in: PubMed
  187. Borsook D, Falkowski O, Rosen H, Comb M, Hyman SE. Opioids modulate stress-induced proenkephalin gene expression in the hypothalamus of transgenic mice: a model of endogenous opioid gene regulation by exogenous opioids. J Neurosci. 1994 Dec; 14(12):7261-71. PMID: 7996174.
    View in: PubMed
  188. Borsook D, Konradi C, Falkowski O, Comb M, Hyman SE. Molecular mechanisms of stress-induced proenkephalin gene regulation: CREB interacts with the proenkephalin gene in the mouse hypothalamus and is phosphorylated in response to hyperosmolar stress. Mol Endocrinol. 1994 Feb; 8(2):240-8. PMID: 8170480; PMCID: PMC4205567.
  189. Borsook D, Falkowski O, Burstein R, Strassman A, Konradi C, Dauber A, Comb M, Hyman SE. Stress-induced regulation of a human proenkephalin-beta-galactosidase fusion gene in the hypothalamus of transgenic mice. Mol Endocrinol. 1994 Jan; 8(1):116-25. PMID: 8152426.
    View in: PubMed
  190. Strassman AM, Vos BP, Mineta Y, Naderi S, Borsook D, Burstein R. Fos-like immunoreactivity in the superficial medullary dorsal horn induced by noxious and innocuous thermal stimulation of facial skin in the rat. J Neurophysiol. 1993 Nov; 70(5):1811-21. PMID: 8294956.
    View in: PubMed
  191. Borsook D, Rosen H, Collard M, Dressler H, Herrup K, Comb MJ, Hyman SE. Expression and regulation of a proenkephalin beta-galactosidase fusion gene in the reproductive system of transgenic mice. Mol Endocrinol. 1992 Sep; 6(9):1502-12. PMID: 1435791.
    View in: PubMed
  192. Comb MJ, Kobierski L, Chu HM, Tan Y, Borsook D, Herrup K, Hyman SE. Regulation of opioid gene expression: a model to understand neural plasticity. NIDA Res Monogr. 1992; 126:98-112. PMID: 1491720.
    View in: PubMed
  193. Borsook D, Richardson GS, Moore-Ede MC, Brennan MJ. GABA and circadian timekeeping: implications for manic-depression and sleep disorders. Med Hypotheses. 1986 Feb; 19(2):185-98. PMID: 3010063.
    View in: PubMed
  194. Brennan MJ, Volicer L, Moore-Ede MC, Borsook D. Daily rhythms of benzodiazepine receptor numbers in frontal lobe and cerebellum of the rat. Life Sci. 1985 Jun 17; 36(24):2333-7. PMID: 2989633.
    View in: PubMed
  195. Mannell A, Borsook D, Diamantes T. Recurrent ulceration and hypergastrinaemia in the gastrectomized patient. An approach to diagnosis. S Afr J Surg. 1983 Mar; 21(1):35-42. PMID: 6879350.
    View in: PubMed
  196. Borsook D, Laburn H, Mitchell D. The febrile responses in rabbits and rats to leucocyte pyrogens of different species. J Physiol. 1978 Jun; 279:113-20. PMID: 671345; PMCID: PMC1282604.
  197. Borsook D, Laburn HP, Rosendorff C, Willies GH, Woolf CJ. A dissociation between temperature regulation and fever in the rabbit. J Physiol. 1977 Apr; 266(2):423-33. PMID: 140237; PMCID: PMC1283573.
Borsook's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts Expand Description
_
Co-Authors Expand Description
_
Similar People Expand Description
_
Same Department Expand Description
Physical Neighbors Expand Description
_