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profileDavid Raphael Elmaleh, PH.D.

TitleAssociate Professor of Radiology, Part-time
InstitutionMassachusetts General Hospital
DepartmentRadiology
AddressMassachusetts General Hospital
Nuclear Medicine Division/Department of Radiology
55 Fruit St
Boston MA 02114
Phone617/726-6748
Fax617/726-5123
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R01NS020998     (ELMALEH, DAVID R)Sep 9, 1985 - Aug 31, 1988
NIH/NINDS
BRAIN GAMMA AND POSITRON LABELED PHENTERMINE ANALOGS
Role: Principal Investigator

R01HL029462     (ELMALEH, DAVID R)Aug 1, 1982 - Sep 29, 1989
NIH/NHLBI
MYOCARDIAL GAMMA &POSITRON LABELED FATTY ACID ANALOGS
Role: Principal Investigator

R01CA026371     (ELMALEH, DAVID R)Aug 1, 1979 - Jul 31, 1987
NIH/NCI
RADIOPHARMACEUTICALS FOR POSITRON TOMOGRAPHY AND CANCER
Role: Principal Investigator
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This researcher has shared information about their research resources
in the eagle-i Network. To update or add resource records, contact
eagle-i@hms.harvard.edu.
PET Core (MGH) - Core services (4) and Instruments (8)

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Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Hori Y, Takeda S, Cho H, Wegmann S, Shoup TM, Takahashi K, Irimia D, Elmaleh DR, Hyman BT, Hudry E. A Food and Drug Administration-approved asthma therapeutic agent impacts amyloid ß in the brain in a transgenic model of Alzheimer disease. J Biol Chem. 2015 Jan 23; 290(4):1966-78. PMID: 25468905; PMCID: PMC4303653.
  2. Tian Y, Zhang X, Li Y, Shoup TM, Teng X, Elmaleh DR, Moore A, Ran C. Crown ethers attenuate aggregation of amyloid beta of Alzheimer's disease. Chem Commun (Camb). 2014 Dec 25; 50(99):15792-5. PMID: 25372154; PMCID: PMC4617529.
  3. Zhao G, Yu YM, Shoup TM, Elmaleh DR, Bonab AA, Tompkins RG, Fischman AJ. Membrane potential-dependent uptake of 18F-triphenylphosphonium--a new voltage sensor as an imaging agent for detecting burn-induced apoptosis. J Surg Res. 2014 May 15; 188(2):473-9. PMID: 24582214; PMCID: PMC3988254.
  4. Larvie M, Shoup T, Chang WC, Chigweshe L, Hartshorn K, White MR, Stahl GL, Elmaleh DR, Takahashi K. Mannose-binding lectin binds to amyloid ß protein and modulates inflammation. J Biomed Biotechnol. 2012; 2012:929803. PMID: 22536027; PMCID: PMC3322523.
  5. Gurm GS, Danik SB, Shoup TM, Weise S, Takahashi K, Laferrier S, Elmaleh DR, Gewirtz H. 4-[18F]-tetraphenylphosphonium as a PET tracer for myocardial mitochondrial membrane potential. JACC Cardiovasc Imaging. 2012 Mar; 5(3):285-92. PMID: 22421174.
    View in: PubMed
  6. Shoup TM, Elmaleh DR, Brownell AL, Zhu A, Guerrero JL, Fischman AJ. Evaluation of (4-[18F]Fluorophenyl)triphenylphosphonium ion. A potential myocardial blood flow agent for PET. Mol Imaging Biol. 2011 Jun; 13(3):511-517. PMID: 20563755.
    View in: PubMed
  7. Gomperts SN, Rentz DM, Moran E, Becker JA, Locascio JJ, Klunk WE, Mathis CA, Elmaleh DR, Shoup T, Fischman AJ, Hyman BT, Growdon JH, Johnson KA. Imaging amyloid deposition in Lewy body diseases. Neurology. 2008 Sep 16; 71(12):903-10. PMID: 18794492; PMCID: PMC2637553.
  8. Elmaleh DR, Fischman AJ, Tawakol A, Zhu A, Shoup TM, Hoffmann U, Brownell AL, Zamecnik PC. Detection of inflamed atherosclerotic lesions with diadenosine-5',5'''-P1,P4-tetraphosphate (Ap4A) and positron-emission tomography. Proc Natl Acad Sci U S A. 2006 Oct 24; 103(43):15992-6. PMID: 17038498; PMCID: PMC1599947.
  9. Madras BK, Fahey MA, Goulet M, Lin Z, Bendor J, Goodrich C, Meltzer PC, Elmaleh DR, Livni E, Bonab AA, Fischman AJ. Dopamine transporter (DAT) inhibitors alleviate specific parkinsonian deficits in monkeys: association with DAT occupancy in vivo. J Pharmacol Exp Ther. 2006 Nov; 319(2):570-85. PMID: 16885433.
    View in: PubMed
  10. Elmaleh DR, Brown NV, Geiben-Lynn R. Anti-viral activity of human antithrombin III. Int J Mol Med. 2005 Aug; 16(2):191-200. PMID: 16012749.
    View in: PubMed
  11. Shoup TM, Elmaleh DR, Bonab AA, Fischman AJ. Evaluation of trans-9-18F-fluoro-3,4-Methyleneheptadecanoic acid as a PET tracer for myocardial fatty acid imaging. J Nucl Med. 2005 Feb; 46(2):297-304. PMID: 15695790.
    View in: PubMed
  12. Yu M, Någren K, Chen YI, Livni E, Elmaleh D, Kozikowski A, Wang X, Jokivarsi K, Brownell AL. Radiolabeling and biodistribution of methyl 2-(methoxycarbonyl)-2-(methylamino) bicyclo[2.1.1] -hexane -5-carboxylate, a potential neuroprotective drug. Life Sci. 2003 Aug 08; 73(12):1577-85. PMID: 12865097.
    View in: PubMed
  13. Choi SW, Elmaleh DR, Hanson RN, Shoup TM, Fischman AJ. Novel (bisarylmethoxy)butylpiperidine analogues as neurotransmitter transporter inhibitors with activity at dopamine receptor sites. Bioorg Med Chem. 2002 Dec; 10(12):4091-102. PMID: 12413863.
    View in: PubMed
  14. Trzcinska M, Pimentel P, Stellar JR, Hanson RN, Choi SW, Elmaleh DR, Zhang J, Prakash KR, Tamiz AP, Kozikowski AP, Johnson KM, Smith MP, Babich JW. Novel monoamine transporter ligands reduce cocaine-induced enhancement of brain stimulation reward. Pharmacol Biochem Behav. 2001 Jan; 68(1):171-80. PMID: 11274722.
    View in: PubMed
  15. Choi SW, Elmaleh DR, Hanson RN, Fischman AJ. Novel 3-aminomethyl- and 4-aminopiperidine analogues of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazines: synthesis and evaluation as dopamine transporter ligands. J Med Chem. 2000 Jan 27; 43(2):205-13. PMID: 10649976.
    View in: PubMed
  16. Choi SW, Elmaleh DR, Hanson RN, Fischman AJ. Design, synthesis, and biological evaluation of novel non-piperazine analogues of 1-[2-(diphenylmethoxy)ethyl]- and 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines as dopamine transporter inhibitors. J Med Chem. 1999 Sep 09; 42(18):3647-56. PMID: 10479296.
    View in: PubMed
  17. Brownell AL, Jenkins BG, Elmaleh DR, Deacon TW, Spealman RD, Isacson O. Combined PET/MRS brain studies show dynamic and long-term physiological changes in a primate model of Parkinson disease. Nat Med. 1998 Nov; 4(11):1308-12. PMID: 9809556.
    View in: PubMed
  18. Madras BK, Meltzer PC, Liang AY, Elmaleh DR, Babich J, Fischman AJ. Altropane, a SPECT or PET imaging probe for dopamine neurons: I. Dopamine transporter binding in primate brain. Synapse. 1998 Jun; 29(2):93-104. PMID: 9593100.
    View in: PubMed
  19. Fischman AJ, Bonab AA, Babich JW, Palmer EP, Alpert NM, Elmaleh DR, Callahan RJ, Barrow SA, Graham W, Meltzer PC, Hanson RN, Madras BK. Rapid detection of Parkinson's disease by SPECT with altropane: a selective ligand for dopamine transporters. Synapse. 1998 Jun; 29(2):128-41. PMID: 9593103.
    View in: PubMed
  20. Madras BK, Gracz LM, Meltzer PC, Liang AY, Elmaleh DR, Kaufman MJ, Fischman AJ. Altropane, a SPECT or PET imaging probe for dopamine neurons: II. Distribution to dopamine-rich regions of primate brain. Synapse. 1998 Jun; 29(2):105-15. PMID: 9593101.
    View in: PubMed
  21. Madras BK, Gracz LM, Fahey MA, Elmaleh D, Meltzer PC, Liang AY, Stopa EG, Babich J, Fischman AJ. Altropane, a SPECT or PET imaging probe for dopamine neurons: III. Human dopamine transporter in postmortem normal and Parkinson's diseased brain. Synapse. 1998 Jun; 29(2):116-27. PMID: 9593102.
    View in: PubMed
  22. Elmaleh DR, Narula J, Babich JW, Petrov A, Fischman AJ, Khaw BA, Rapaport E, Zamecnik PC. Rapid noninvasive detection of experimental atherosclerotic lesions with novel 99mTc-labeled diadenosine tetraphosphates. Proc Natl Acad Sci U S A. 1998 Jan 20; 95(2):691-5. PMID: 9435254; PMCID: PMC18482.
  23. Fischman AJ, Babich JW, Elmaleh DR, Barrow SA, Meltzer P, Hanson RN, Madras BK. SPECT imaging of dopamine transporter sites in normal and MPTP-Treated rhesus monkeys. J Nucl Med. 1997 Jan; 38(1):144-50. PMID: 8998169.
    View in: PubMed
  24. Fischman AJ, Bonab AA, Babich JW, Alpert NM, Rauch SL, Elmaleh DR, Shoup TM, Williams SA, Rubin RH. Positron emission tomographic analysis of central 5-hydroxytryptamine2 receptor occupancy in healthy volunteers treated with the novel antipsychotic agent, ziprasidone. J Pharmacol Exp Ther. 1996 Nov; 279(2):939-47. PMID: 8930203.
    View in: PubMed
  25. Brownell AL, Elmaleh DR, Meltzer PC, Shoup TM, Brownell GL, Fischman AJ, Madras BK. Cocaine congeners as PET imaging probes for dopamine terminals. J Nucl Med. 1996 Jul; 37(7):1186-92. PMID: 8965196.
    View in: PubMed
  26. Elmaleh DR, Fischman AJ, Shoup TM, Byon C, Hanson RN, Liang AY, Meltzer PC, Madras BK. Preparation and biological evaluation of iodine-125-IACFT: a selective SPECT agent for imaging dopamine transporter sites. J Nucl Med. 1996 Jul; 37(7):1197-202. PMID: 8965198.
    View in: PubMed
  27. Zaknun J, Elmaleh DR, Guan JH, Fischman AJ. Effect of monounsaturation of a branched fatty acid on organ selectivity. J Nucl Med. 1995 Nov; 36(11):2062-8. PMID: 7472600.
    View in: PubMed
  28. Herman LW, Fischman AJ, Tompkins RG, Hanson RN, Byon C, Strauss HW, Elmaleh DR. The use of pentafluorophenyl derivatives for the 18F labelling of proteins. Nucl Med Biol. 1994 Oct; 21(7):1005-10. PMID: 9234356.
    View in: PubMed
  29. Shoup TM, Fischman AJ, Jaywook S, Babich JW, Strauss HW, Elmaleh DR. Synthesis of fluorine-18-labeled biotin derivatives: biodistribution and infection localization. J Nucl Med. 1994 Oct; 35(10):1685-90. PMID: 7931672.
    View in: PubMed
  30. Melder RJ, Elmaleh D, Brownell AL, Brownell GL, Jain RK. A method for labeling cells for positron emission tomography (PET) studies. J Immunol Methods. 1994 Sep 30; 175(1):79-87. PMID: 7930641.
    View in: PubMed
  31. Meng J, Elmaleh DR, Jyawook S, Weiss S, Alpert NM, Babich JW, Tompkins RG, Fischman AJ. Synthesis of 2-[18F]fluoro-2-deoxy-L-glucose and positron emission tomography studies in monkeys. Nucl Med Biol. 1994 May; 21(4):633-40. PMID: 9234321.
    View in: PubMed
  32. Wüllner U, Pakzaban P, Brownell AL, Hantraye P, Burns L, Shoup T, Elmaleh D, Petto AJ, Spealman RD, Brownell GL, et al. Dopamine terminal loss and onset of motor symptoms in MPTP-treated monkeys: a positron emission tomography study with 11C-CFT. Exp Neurol. 1994 Apr; 126(2):305-9. PMID: 7925829.
    View in: PubMed
  33. Elmaleh DR, Livni E, Alpert NM, Strauss HW, Buxton R, Fischman AJ. Myocardial extraction of 1-[11C] betamethylheptadecanoic acid. J Nucl Med. 1994 Mar; 35(3):496-503. PMID: 8113905.
    View in: PubMed
  34. Madras BK, Elmaleh DR, Meltzer PC, Liang AY, Brownell GL, Brownell AL. Positron emission tomography of cocaine binding sites on the dopamine transporter. NIDA Res Monogr. 1994; 138:57-69. PMID: 7603545.
    View in: PubMed
  35. Jones GS, Elmaleh DR, Strauss HW, Fischman AJ. Synthesis and biodistribution of a new 99mtechnetium fatty acid. Nucl Med Biol. 1994 Jan; 21(1):117-23. PMID: 9234273.
    View in: PubMed
  36. Brownell AL, Hantraye P, Wullner U, Hamberg L, Shoup T, Elmaleh DR, Frim DM, Madras BK, Brownell GL, Rosen BR, et al. PET- and MRI-based assessment of glucose utilization, dopamine receptor binding, and hemodynamic changes after lesions to the caudate-putamen in primates. Exp Neurol. 1994 Jan; 125(1):41-51. PMID: 7905836.
    View in: PubMed
  37. Wakasugi S, Fischman AJ, Babich JW, Callahan RJ, Elmaleh DR, Wilkinson R, Strauss HW. Myocardial substrate utilization and left ventricular function in adriamycin cardiomyopathy. J Nucl Med. 1993 Sep; 34(9):1529-35. PMID: 8355075.
    View in: PubMed
  38. Nakai K, Ahmad M, Nakaki M, Wilkinson R, Callahan RJ, Elmaleh DR, Fischman AJ, Strauss HW. Serial course of left ventricular function, perfusion and fatty acid uptake in the cardiomyopathic hamster. J Nucl Med. 1993 Aug; 34(8):1309-15. PMID: 8326390.
    View in: PubMed
  39. Elmaleh DR, Padmanabhan S, Hassan MA, Correia JA, Herman LW, Hanson RN, Strauss HW. Synthesis and evaluation of 1-[11C]methyl-4-aryl-piperazinium salts as myocardial imaging agents. Nucl Med Biol. 1993 May; 20(4):427-33. PMID: 8504285.
    View in: PubMed
  40. Elmaleh DR, Kizuka H, Hanson RN, Jones GS, Herman LW, Strauss HW. Structure-localization relationships of 11C-labeled phentermine derivatives: effect of aromatic substitution. Appl Radiat Isot. 1993 May; 44(5):821-9. PMID: 8485509.
    View in: PubMed
  41. Meltzer PC, Liang AY, Brownell AL, Elmaleh DR, Madras BK. Substituted 3-phenyltropane analogs of cocaine: synthesis, inhibition of binding at cocaine recognition sites, and positron emission tomography imaging. J Med Chem. 1993 Apr 02; 36(7):855-62. PMID: 8464040.
    View in: PubMed
  42. Kizuka H, Elmaleh DR. Selective monomethylation of the primary amine function using [11C]CH3I and the N-trifluoroacetyl derivative: preparation of N-[11C-methyl]chlorphentermine. Nucl Med Biol. 1993 Feb; 20(2):239-42. PMID: 8448579.
    View in: PubMed
  43. Hantraye P, Brownell AL, Elmaleh D, Spealman RD, Wüllner U, Brownell GL, Madras BK, Isacson O. Dopamine fiber detection by [11C]-CFT and PET in a primate model of parkinsonism. Neuroreport. 1992 Mar; 3(3):265-8. PMID: 1515582.
    View in: PubMed
  44. Livni E, Fischman AJ, Ray S, Sinclair I, Elmaleh DR, Alpert NM, Weiss S, Correia JA, Webb D, Dahl R, et al. Synthesis of 18F-labeled fluconazole and positron emission tomography studies in rabbits. Int J Rad Appl Instrum B. 1992 Feb; 19(2):191-9. PMID: 1601672.
    View in: PubMed
  45. Schumacher JM, Hantraye P, Brownell AL, Riche D, Madras BK, Davenport PD, Maziere M, Elmaleh DR, Brownell GL, Isacson O. A primate model of Huntington's disease: functional neural transplantation and CT-guided stereotactic procedures. Cell Transplant. 1992; 1(4):313-22. PMID: 1344304.
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  46. Fischman AJ, Alpert NM, Livni E, Ray S, Sinclair I, Elmaleh DR, Weiss S, Correia JA, Webb D, Liss R, et al. Pharmacokinetics of 18F-labeled fluconazole in rabbits with candidal infections studied with positron emission tomography. J Pharmacol Exp Ther. 1991 Dec; 259(3):1351-9. PMID: 1762083.
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  47. Saito T, Yasuda T, Gold HK, Leinbach R, Livni E, Elmaleh D, Callahan R, Barlai-Kovach M, Wilkinson R, Fischman AJ, et al. Differentiation of regional perfusion and fatty acid uptake in zones of myocardial injury. Nucl Med Commun. 1991 Aug; 12(8):663-75. PMID: 1780108.
    View in: PubMed
  48. Nishizawa K, Okunieff P, Elmaleh D, McKusick KA, Strauss HW, Suit HD. Blood flow of human soft tissue sarcomas measured by thallium-201 scanning: prediction of tumor response to radiation. Int J Radiat Oncol Biol Phys. 1991 Mar; 20(3):593-7. PMID: 1995546.
    View in: PubMed
  49. Steichen JD, Weiss MJ, Elmaleh DR, Martuza RL. Enhanced in vitro uptake and retention of 3H-tetraphenylphosphonium by nervous system tumor cells. J Neurosurg. 1991 Jan; 74(1):116-22. PMID: 1984490.
    View in: PubMed
  50. Fink GD, Montgomery JA, David F, Garneau M, Livni E, Elmaleh D, Strauss HW, Brunengraber H. Metabolism of beta-methyl-heptadecanoic acid in the perfused rat heart and liver. J Nucl Med. 1990 Nov; 31(11):1823-30. PMID: 2230995.
    View in: PubMed
  51. Carter EA, Barli-Kovach M, Elmaleh D, Livni E, Strauss HW. Acute alcohol ingestion reduces fatty acid extraction of the heart, liver, and small intestine. Alcohol Clin Exp Res. 1990 Oct; 14(5):781-4. PMID: 2264611.
    View in: PubMed
  52. Livni E, Ito S, Kassis AI, Elmaleh DR. (3H/14C)beta-methylheptadecanoic acid subcellular distribution and lipid incorporation in mouse heart. Lipids. 1990 Apr; 25(4):238-40. PMID: 2345498.
    View in: PubMed
  53. Miller DD, Gill JB, Livni E, Elmaleh DR, Aretz T, Boucher CA, Strauss HW. Fatty acid analogue accumulation: a marker of myocyte viability in ischemic-reperfused myocardium. Circ Res. 1988 Oct; 63(4):681-92. PMID: 3048774.
    View in: PubMed
  54. Kairento AL, Livni E, Mattila S, Harjula A, Porkka L, Lindroth L, Elmaleh DR. Comparative evaluation of [123I]14-p-iodophenyl-beta-methyltetradecanoic acid and thallium-201 in the detection of infarcted areas in the dog heart using SPECT. Int J Rad Appl Instrum B. 1988; 15(3):333-8. PMID: 3260230.
    View in: PubMed
  55. Jones GS, Livni E, Strauss HW, Hanson RN, Elmaleh DR. Synthesis and biologic evaluation of 1-[11C]-3,3-dimethylheptadecanoic acid. J Nucl Med. 1988 Jan; 29(1):68-72. PMID: 3335930.
    View in: PubMed
  56. Lauffer RB, Vincent AC, Padmanabhan S, Villringer A, Saini S, Elmaleh DR, Brady TJ. Hepatobiliary MR contrast agents: 5-substituted iron-EHPG derivatives. Magn Reson Med. 1987 Jun; 4(6):582-90. PMID: 3613958.
    View in: PubMed
  57. Livni E, Spellman JP, Correia JA, Alpert NM, Brownell GL, Strauss HW, Elmaleh DR. [11C]MPTP: a potential tracer for Parkinson's disease research in laboratory animals. J Nucl Med. 1986 Oct; 27(10):1600-3. PMID: 3489823.
    View in: PubMed
  58. Yamamoto K, Som P, Brill AB, Yonekura Y, Srivastava SC, Meinken GE, Iwai J, Goodman MM, Knapp FF, Elmaleh DR, et al. Dual tracer autoradiographic study of beta-methyl-(1-14C) heptadecanoic acid and 15-p-(131I)-iodophenyl-beta-methylpentadecanoic acid in normotensive and hypertensive rats. J Nucl Med. 1986 Jul; 27(7):1178-83. PMID: 3723193.
    View in: PubMed
  59. Miller DD, Gill JB, Fischman AJ, Callahan RJ, Elmaleh DR, Boucher CA, Strauss HW. New radionuclides for cardiac imaging. Prog Cardiovasc Dis. 1986 May-Jun; 28(6):419-34. PMID: 3517962.
    View in: PubMed
  60. Strauss HW, Elmaleh D. Musings on PET and SPECT. Circulation. 1986 Apr; 73(4):611-4. PMID: 3485018.
    View in: PubMed
  61. Kizuka H, Elmaleh DR, Boudreaux GJ, Strauss HW, Ackerman RH, Brownell GL. N-[11C-Methyl]chlorphentermine and N,N-[11C-dimethyl]chlorphentermine as brain blood-flow agents for positron emission tomography. J Nucl Med. 1986 Apr; 27(4):532-7. PMID: 3486957.
    View in: PubMed
  62. Bianco JA, Elmaleh DR, Leppo JA, King MA, Moring A, Livni E, Espinoza E, Alpert JS, Strauss HW. Effect of glucose and insulin infusion on the myocardial extraction of a radioiodinated methyl-substituted fatty acid. Eur J Nucl Med. 1986; 12(3):120-4. PMID: 3530771.
    View in: PubMed
  63. Miller DD, Elmaleh DR, McKusick KA, Boucher CA, Callahan RJ, Strauss HW. Radiopharmaceuticals for cardiac imaging. Radiol Clin North Am. 1985 Dec; 23(4):765-81. PMID: 3906755.
    View in: PubMed
  64. Livni E, Elmaleh DR, Barlai-Kovach MM, Goodman MM, Knapp FF, Strauss HW. Radioiodinated beta-methyl phenyl fatty acids as potential tracers for myocardial imaging and metabolism. Eur Heart J. 1985 Aug; 6 Suppl B:85-9. PMID: 4085510.
    View in: PubMed
  65. Kairento AL, Brownell GL, Elmaleh DR, Swartz MR. Comparative measurement of regional blood flow, oxygen and glucose utilisation in soft tissue tumour of rabbit with positron imaging. Br J Radiol. 1985 Jul; 58(691):637-43. PMID: 3874674.
    View in: PubMed
  66. Elmaleh DR, Livni E, Okada R, Needham FL, Schleuederberg J, Strauss HW. The synthesis and evaluation of radioiodinated 14-(iodophenyl)-3-(R,S)methyltetradecanoic acid. Nucl Med Commun. 1985 May; 6(5):287-97. PMID: 4034126.
    View in: PubMed
  67. Neumeyer JL, Guan JH, Niznik HB, Dumbrille-Ross A, Seeman P, Padmanabhan S, Elmaleh DR. Novel photoaffinity label for the dopamine D2 receptor: synthesis of 4-azido-5-iodo-2-methoxy-N-[1-(phenylmethyl)-4-piperidinyl] benzamide (iodoazidoclebopride, IAC) and the corresponding 125I-labeled analogue (125IAC). J Med Chem. 1985 Apr; 28(4):405-7. PMID: 3156993.
    View in: PubMed
  68. Brownell GL, Kairento AL, Swartz M, Elmaleh DR. Positron emission tomography in oncology--the Massachusetts General Hospital experience. Semin Nucl Med. 1985 Apr; 15(2):201-9. PMID: 3873706.
    View in: PubMed
  69. Yonekura Y, Brill AB, Som P, Yamamoto K, Srivastava SC, Iwai J, Elmaleh DR, Livni E, Strauss HW, Goodman MM, et al. Regional myocardial substrate uptake in hypertensive rats: a quantitative autoradiographic measurement. Science. 1985 Mar 22; 227(4693):1494-6. PMID: 3975623.
    View in: PubMed
  70. Kizuka H, Elmaleh DR, Brownell GL, Strauss HW, Hanson RN. Synthesis and evaluation of p-iodo-phentermine (IP) as a brain perfusion imaging agent. Nucl Med Commun. 1985 Jan; 6(1):49-56. PMID: 3843616.
    View in: PubMed
  71. Okada RD, Knapp FF, Goodman MM, Elmaleh D, Strauss HW. Tellurium-labeled fatty-acid analogs: relationship of heteroatom position to myocardial kinetics. Eur J Nucl Med. 1985; 11(5):156-61. PMID: 4065154.
    View in: PubMed
  72. Hanson RN, Jones GS, Franke L, Kizuka H, Elmaleh DR. Preparation and evaluation of 3-[125I]iodo-4-aminophentermine as a brain perfusion imaging agent. Comparison with labeled phentermine derivatives. Int J Nucl Med Biol. 1985; 12(4):321-5. PMID: 4086198.
    View in: PubMed
  73. Buxton RB, Wechsler LR, Alpert NM, Ackerman RH, Elmaleh DR, Correia JA. Measurement of brain pH using 11CO2 and positron emission tomography. J Cereb Blood Flow Metab. 1984 Mar; 4(1):8-16. PMID: 6420427.
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  74. Elmaleh DR, Zamecnik PC, Castronovo FP, Strauss HW, Rapaport E. 99mTc-labeled nucleotides as tumor-seeking radiodiagnostic agents. Proc Natl Acad Sci U S A. 1984 Feb; 81(3):918-21. PMID: 6322177; PMCID: PMC344950.
  75. Kearfott KJ, Elmaleh DR, Goodman M, Correia JA, Alpert NM, Ackerman RH, Brownell GL, Strauss WH. Comparison of 2- and 3-18F-fluoro-deoxy-D-glucose for studies of tissue metabolism. Int J Nucl Med Biol. 1984; 11(1):15-22. PMID: 6610664.
    View in: PubMed
  76. Sullivan PJ, Werre J, Elmaleh DR, Okada RD, Kopiwoda SY, Castronovo FP, McKusick KA, Strauss HW. A comparison of the technetium-labeled myocardial agents DiArs and DMPE to 201Tl in experimental animals. Int J Nucl Med Biol. 1984; 11(1):3-10. PMID: 6735606.
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  77. Kairento AL, Brownell GL, Schluederberg J, Elmaleh DR. Regional blood-flow measurement in rabbit soft-tissue tumor with positron imaging using the C15O2 steady-state and labeled microspheres. J Nucl Med. 1983 Dec; 24(12):1135-42. PMID: 6417285.
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  78. Levy S, Livni E, Elmaleh DR, Varnum DA, Brownell GL. 2-deoxy-2-[18F]fluoro-3-o-methyl-D-glucose synthesis and animal biodistribution studies. Int J Appl Radiat Isot. 1983 Nov; 34(11):1560-2. PMID: 6642715.
    View in: PubMed
  79. Brownell GL, Kearfott KJ, Kairento AL, Elmaleh DR, Alpert NM, Correia JA, Wechsler L, Ackerman RH. Quantitation of regional cerebral glucose metabolism. J Comput Assist Tomogr. 1983 Oct; 7(5):919-24. PMID: 6886150.
    View in: PubMed
  80. Okada RD, Elmaleh D, Werre GS, Strauss HW. Myocardial kinetics of 123I-labeled-16-hexadecanoic acid. Eur J Nucl Med. 1983; 8(5):211-7. PMID: 6873097.
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  81. Elmaleh DR, Livni E, Levy S, Varnum D, Strauss HW, Brownell GL. Comparison of 11C and 14C-labeled fatty acids and their beta-methyl analogs. Int J Nucl Med Biol. 1983; 10(4):181-7. PMID: 6607238.
    View in: PubMed
  82. Levy S, Elmaleh DR, Livni E. A new method using anhydrous [18F]fluoride to radiolabel 2-[18F]fluoro-2-deoxy-D-glucose. J Nucl Med. 1982 Oct; 23(10):918-22. PMID: 7119887.
    View in: PubMed
  83. Okada RD, Knapp FF, Elmaleh DR, Yasuda T, Boucher CA, Strauss HW. Tellurium-123m-labeled-9-telluraheptadecanoic acid: a possible cardiac imaging agent. Circulation. 1982 Feb; 65(2):305-10. PMID: 7053888.
    View in: PubMed
  84. Livni E, Elmaleh DR, Levy S, Brownell GL, Strauss WH. Beta-methyl[1-11C]heptadecanoic acid: a new myocardial metabolic tracer for positron emission tomography. J Nucl Med. 1982 Feb; 23(2):169-75. PMID: 6977020.
    View in: PubMed
  85. Elmaleh DR, Knapp FF, Yasuda T, Coffey JL, Kopiwoda S, Okada R, Strauss HW. Myocardial imaging with 9-[Te-123m]telluraheptadecanoic acid. J Nucl Med. 1981 Nov; 22(11):994-9. PMID: 7299486.
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  86. Goodman MM, Elmaleh DR, Kearfott KJ, Ackerman RH, Hoop B, Brownell GL, Alpert NM, Strauss HW. F-18-labeled 3-deoxy-3-fluoro-D-glucose for the study of regional metabolism in the brain and heart. J Nucl Med. 1981 Feb; 22(2):138-44. PMID: 6970254.
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  87. Gronemeyer SA, Brownell GL, Elmaleh DR, Athanasoulis CA. Transverse section imaging of soft tissue tumors and peripheral vascular disease. Semin Nucl Med. 1980 Oct; 10(4):392-9. PMID: 6968454.
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  88. Brownell GL, Ackerman RH, Strauss HW, Elmaleh DR, Cochavi S, Alpert N, Correia JA, Kearfott KJ, Taveras J. Preliminary imaging results with 18F-2-fluoro-2-deoxy-D-glucose. J Comput Assist Tomogr. 1980 Aug; 4(4):473-7. PMID: 6771307.
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  89. Elmaleh DR, Hnatowitch DJ, Cochavi S, McKusick KA, Brownell GL, Strauss WH. Emission tomographic images of the skull with fluorine-18. Int J Nucl Med Biol. 1980; 7(3):289-93. PMID: 6969239.
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  90. Cochavi S, Pohost GM, Elmaleh DR, Strauss HW. Transverse-sectional imaging with Na18F in myocardial infarction. J Nucl Med. 1979 Oct; 20(10):1013-7. PMID: 317092.
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  91. Hnatowich DJ, Kulprathipanja S, Evans G, Elmaleh D. A comparison of positron-emitting blood pool imaging agents. Int J Appl Radiat Isot. 1979 Jun; 30(6):335-40. PMID: 489143.
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  92. Ahluwalia B, Javaheri S, Eldred E, Pappagianopoulos P, Elmaleh D, Hales CA, Brownell GL, Kazemi H. Regional delivery of radioaerosol. J Nucl Med. 1979 Mar; 20(3):272. PMID: 24180060.
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  93. Kulprathipanja S, Hnatowich DJ, Beh R, Elmaleh D. Formation constants of gallium- and indium-transferrin. Int J Nucl Med Biol. 1979; 6(2):138-41. PMID: 113356.
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