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profileMathias Lichterfeld, M.D.

TitleAssociate Professor of Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
Jackson 5
55 Fruit St
Boston MA 02114
Phone617/724-7516
Fax617/726-5411
vCardDownload vCard (login for email)

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Lee GQ, Lichterfeld M. Diversity of HIV-1 reservoirs in CD4+ T-cell subpopulations. Curr Opin HIV AIDS. 2016 Jul; 11(4):383-7. PMID: 27023286.
    View in: PubMed
  2. Jones RB, Mueller S, O'Connor R, Rimpel K, Sloan DD, Karel D, Wong HC, Jeng EK, Thomas AS, Whitney JB, Lim SY, Kovacs C, Benko E, Karandish S, Huang SH, Buzon MJ, Lichterfeld M, Irrinki A, Murry JP, Tsai A, Yu H, Geleziunas R, Trocha A, Ostrowski MA, Irvine DJ, Walker BD. A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes. PLoS Pathog. 2016 Apr; 12(4):e1005545. PMID: 27082643.
    View in: PubMed
  3. Kiselinova M, De Spiegelaere W, Buzon MJ, Malatinkova E, Lichterfeld M, Vandekerckhove L. Correction: Integrated and Total HIV-1 DNA Predict Ex Vivo Viral Outgrowth. PLoS Pathog. 2016 Mar; 12(3):e1005532. PMID: 27003005.
    View in: PubMed
  4. Kiselinova M, De Spiegelaere W, Buzon MJ, Malatinkova E, Lichterfeld M, Vandekerckhove L. Integrated and Total HIV-1 DNA Predict Ex Vivo Viral Outgrowth. PLoS Pathog. 2016 Mar; 12(3):e1005472. PMID: 26938995.
    View in: PubMed
  5. Sun H, Kim D, Li X, Kiselinova M, Ouyang Z, Vandekerckhove L, Shang H, Rosenberg ES, Yu XG, Lichterfeld M. Th1/17 Polarization of CD4 T Cells Supports HIV-1 Persistence during Antiretroviral Therapy. J Virol. 2015 Nov 15; 89(22):11284-93. PMID: 26339043.
    View in: PubMed
  6. Olesen R, Vigano S, Rasmussen TA, Søgaard OS, Ouyang Z, Buzon M, Bashirova A, Carrington M, Palmer S, Brinkmann CR, Yu XG, Østergaard L, Tolstrup M, Lichterfeld M. Innate Immune Activity Correlates with CD4 T Cell-Associated HIV-1 DNA Decline during Latency-Reversing Treatment with Panobinostat. J Virol. 2015 Oct; 89(20):10176-89. PMID: 26223643; PMCID: PMC4580197 [Available on 04/15/16].
  7. Martin-Gayo E, Buzon MJ, Ouyang Z, Hickman T, Cronin J, Pimenova D, Walker BD, Lichterfeld M, Yu XG. Potent Cell-Intrinsic Immune Responses in Dendritic Cells Facilitate HIV-1-Specific T Cell Immunity in HIV-1 Elite Controllers. PLoS Pathog. 2015 Jun; 11(6):e1004930. PMID: 26067651; PMCID: PMC4466270.
  8. Vigano S, Negron J, Ouyang Z, Rosenberg ES, Walker BD, Lichterfeld M, Yu XG. Prolonged Antiretroviral Therapy Preserves HIV-1-Specific CD8 T Cells with Stem Cell-Like Properties. J Virol. 2015 Aug; 89(15):7829-40. PMID: 25995260; PMCID: PMC4505639 [Available on 02/01/16].
  9. Ouyang Z, Buzon MJ, Zheng L, Sun H, Yu XG, Bosch RJ, Mellors JW, Eron JJ, Gandhi RT, Lichterfeld M. Transcriptional Changes in CD8(+) T Cells During Antiretroviral Therapy Intensified With Raltegravir. Open Forum Infect Dis. 2015 Apr; 2(2):ofv045. PMID: 26380343; PMCID: PMC4567091.
  10. Chahroudi A, Silvestri G, Lichterfeld M. T memory stem cells and HIV: a long-term relationship. Curr HIV/AIDS Rep. 2015 Mar; 12(1):33-40. PMID: 25578055; PMCID: PMC4370789 [Available on 03/01/16].
  11. Ho HP, Rathod P, Louis M, Tada CK, Rahaman S, Mark KJ, Leng J, Dana D, Kumar S, Lichterfeld M, Chang EJ. Studies on quantitative phosphopeptide analysis by matrix-assisted laser desorption/ionization mass spectrometry without label, chromatography or calibration curves. Rapid Commun Mass Spectrom. 2014 Dec 30; 28(24):2681-9. PMID: 25380489; PMCID: PMC4225566 [Available on 12/30/15].
  12. Gaiha GD, McKim KJ, Woods M, Pertel T, Rohrbach J, Barteneva N, Chin CR, Liu D, Soghoian DZ, Cesa K, Wilton S, Waring MT, Chicoine A, Doering T, Wherry EJ, Kaufmann DE, Lichterfeld M, Brass AL, Walker BD. Dysfunctional HIV-specific CD8+ T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis. Immunity. 2014 Dec 18; 41(6):1001-12. PMID: 25526311; PMCID: PMC4312487 [Available on 12/18/15].
  13. Martin-Gayo E, Hickman T, Ouyang Z, Cubas R, Lindqvist M, Kauffman D, Haddad E, Walker B, Lichterfeld M, Yu XG. Dendritic Cells from HIV-1 Neutralizers Efficiently Induce the Generation of CXCR5(+) CXCR3(+) PD1(Lo) CD4 T Cells with B Cell Helper Function. AIDS Res Hum Retroviruses. 2014 Oct; 30 Suppl 1:A74. PMID: 25357934.
    View in: PubMed
  14. Rasmussen TA, Tolstrup M, Brinkmann CR, Olesen R, Erikstrup C, Solomon A, Winckelmann A, Palmer S, Dinarello C, Buzon M, Lichterfeld M, Lewin SR, Østergaard L, Søgaard OS. Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial. Lancet HIV. 2014 Oct; 1(1):e13-21. PMID: 26423811.
    View in: PubMed
  15. Jones RB, O'Connor R, Mueller S, Foley M, Szeto GL, Karel D, Lichterfeld M, Kovacs C, Ostrowski MA, Trocha A, Irvine DJ, Walker BD. Histone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytes. PLoS Pathog. 2014 Aug; 10(8):e1004287. PMID: 25122219; PMCID: PMC4133386.
  16. Buzon MJ, Martin-Gayo E, Pereyra F, Ouyang Z, Sun H, Li JZ, Piovoso M, Shaw A, Dalmau J, Zangger N, Martinez-Picado J, Zurakowski R, Yu XG, Telenti A, Walker BD, Rosenberg ES, Lichterfeld M. Long-term antiretroviral treatment initiated at primary HIV-1 infection affects the size, composition, and decay kinetics of the reservoir of HIV-1-infected CD4 T cells. J Virol. 2014 Sep 1; 88(17):10056-65. PMID: 24965451; PMCID: PMC4136362.
  17. Leng J, Ho HP, Buzon MJ, Pereyra F, Walker BD, Yu XG, Chang EJ, Lichterfeld M. A cell-intrinsic inhibitor of HIV-1 reverse transcription in CD4(+) T cells from elite controllers. Cell Host Microbe. 2014 Jun 11; 15(6):717-28. PMID: 24922574; PMCID: PMC4072498.
  18. Jost S, Tomezsko PJ, Rands K, Toth I, Lichterfeld M, Gandhi RT, Altfeld M. CD4+ T-cell help enhances NK cell function following therapeutic HIV-1 vaccination. J Virol. 2014 Aug; 88(15):8349-54. PMID: 24829350; PMCID: PMC4135926.
  19. Bashirova AA, Martin-Gayo E, Jones DC, Qi Y, Apps R, Gao X, Burke PS, Taylor CJ, Rogich J, Wolinsky S, Bream JH, Duggal P, Hussain S, Martinson J, Weintrob A, Kirk GD, Fellay J, Buchbinder SP, Goedert JJ, Deeks SG, Pereyra F, Trowsdale J, Lichterfeld M, Telenti A, Walker BD, Allen RL, Carrington M, Yu XG. LILRB2 interaction with HLA class I correlates with control of HIV-1 infection. PLoS Genet. 2014 Mar; 10(3):e1004196. PMID: 24603468; PMCID: PMC3945438.
  20. Boufassa F, Lechenadec J, Meyer L, Costagliola D, Hunt PW, Pereyra F, Deeks S, Pancino G, Taulera O, Lichterfeld M, Delobel P, Saez-Cirion A, Lambotte O. Blunted response to combination antiretroviral therapy in HIV elite controllers: an international HIV controller collaboration. PLoS One. 2014; 9(1):e85516. PMID: 24465584; PMCID: PMC3894966.
  21. Buzon MJ, Sun H, Li C, Shaw A, Seiss K, Ouyang Z, Martin-Gayo E, Leng J, Henrich TJ, Li JZ, Pereyra F, Zurakowski R, Walker BD, Rosenberg ES, Yu XG, Lichterfeld M. HIV-1 persistence in CD4+ T cells with stem cell-like properties. Nat Med. 2014 Feb; 20(2):139-42. PMID: 24412925; PMCID: PMC3959167.
  22. Buzon MJ, Yang Y, Ouyang Z, Sun H, Seiss K, Rogich J, Le Gall S, Pereyra F, Rosenberg ES, Yu XG, Lichterfeld M. Susceptibility to CD8 T-cell-mediated killing influences the reservoir of latently HIV-1-infected CD4 T cells. J Acquir Immune Defic Syndr. 2014 Jan 1; 65(1):1-9. PMID: 23846565; PMCID: PMC3874432.
  23. Sun H, Buzon MJ, Shaw A, Berg RK, Yu XG, Ferrando-Martinez S, Leal M, Ruiz-Mateos E, Lichterfeld M. Hepatitis C therapy with interferon-a and ribavirin reduces CD4 T-cell-associated HIV-1 DNA in HIV-1/hepatitis C virus-coinfected patients. J Infect Dis. 2014 May 1; 209(9):1315-20. PMID: 24277743; PMCID: PMC3982848.
  24. Novis CL, Archin NM, Buzon MJ, Verdin E, Round JL, Lichterfeld M, Margolis DM, Planelles V, Bosque A. Reactivation of latent HIV-1 in central memory CD4? T cells through TLR-1/2 stimulation. Retrovirology. 2013; 10:119. PMID: 24156240; PMCID: PMC3826617.
  25. Lichterfeld M, Rosenberg ES. Acute HIV-1 infection: a call to action. Ann Intern Med. 2013 Sep 17; 159(6):425-7. PMID: 24042369.
    View in: PubMed
  26. Li C, Toth I, Schulze Zur Wiesch J, Pereyra F, Rychert J, Rosenberg ES, van Lunzen J, Lichterfeld M, Yu XG. Functional characterization of HLA-G? regulatory T cells in HIV-1 infection. PLoS Pathog. 2013 Jan; 9(1):e1003140. PMID: 23382678; PMCID: PMC3561210.
  27. Yang Y, Al-Mozaini M, Buzon MJ, Beamon J, Ferrando-Martinez S, Ruiz-Mateos E, Rosenberg ES, Pereyra F, Yu XG, Lichterfeld M. CD4 T-cell regeneration in HIV-1 elite controllers. AIDS. 2012 Mar 27; 26(6):701-6. PMID: 22301416; PMCID: PMC3729591.
  28. Lichterfeld M, Cung T, Seiss K, Rosenberg ES, Pereyra F, Yu XG. Shelterin dysfunction and p16(INK4a)-mediated growth inhibition in HIV-1-specific CD8 T cells. J Virol. 2012 May; 86(10):5533-40. PMID: 22398292; PMCID: PMC3347267.
  29. Huang J, Al-Mozaini M, Rogich J, Carrington MF, Seiss K, Pereyra F, Lichterfeld M, Yu XG. Systemic inhibition of myeloid dendritic cells by circulating HLA class I molecules in HIV-1 infection. Retrovirology. 2012; 9:11. PMID: 22289474; PMCID: PMC3308926.
  30. Lichterfeld M, Gandhi RT, Simmons RP, Flynn T, Sbrolla A, Yu XG, Basgoz N, Mui S, Williams K, Streeck H, Burgett-Yandow N, Roy G, Janssens M, Pedneault L, Vandepapelière P, Koutsoukos M, Demoitié MA, Bourguignon P, McNally L, Voss G, Altfeld M. Induction of strong HIV-1-specific CD4+ T-cell responses using an HIV-1 gp120/NefTat vaccine adjuvanted with AS02A in antiretroviral-treated HIV-1-infected individuals. J Acquir Immune Defic Syndr. 2012 Jan 1; 59(1):1-9. PMID: 21963936; PMCID: PMC3241906.
  31. Lichterfeld M, Rosenberg ES. Antiretroviral combination therapy markedly reduces risk of heterosexual HIV-1 transmission. Evid Based Med. 2012 Jun; 17(3):95-6. PMID: 22108078.
    View in: PubMed
  32. Lichterfeld M, Yu XG. The emerging role of leukocyte immunoglobulin-like receptors (LILRs) in HIV-1 infection. J Leukoc Biol. 2012 Jan; 91(1):27-33. PMID: 22028331; PMCID: PMC3250304.
  33. Huang J, Yang Y, Al-Mozaini M, Burke PS, Beamon J, Carrington MF, Seiss K, Rychert J, Rosenberg ES, Lichterfeld M, Yu XG. Dendritic cell dysfunction during primary HIV-1 infection. J Infect Dis. 2011 Nov 15; 204(10):1557-62. PMID: 21969335; PMCID: PMC3192192.
  34. Yu XG, Lichterfeld M. Elite control of HIV: p21 (waf-1/cip-1) at its best. Cell Cycle. 2011 Oct 1; 10(19):3213-4. PMID: 21926474; PMCID: PMC3688546.
  35. Lichterfeld M, Zachary KC. Treating HIV-1 Infection: What Might the Future Hold? Ther Adv Chronic Dis. 2011 Sep; 2(5):293-305. PMID: 23251756; PMCID: PMC3513891.
  36. Buzon MJ, Seiss K, Weiss R, Brass AL, Rosenberg ES, Pereyra F, Yu XG, Lichterfeld M. Inhibition of HIV-1 integration in ex vivo-infected CD4 T cells from elite controllers. J Virol. 2011 Sep; 85(18):9646-50. PMID: 21734042; PMCID: PMC3165766.
  37. Chen H, Li C, Huang J, Cung T, Seiss K, Beamon J, Carrington MF, Porter LC, Burke PS, Yang Y, Ryan BJ, Liu R, Weiss RH, Pereyra F, Cress WD, Brass AL, Rosenberg ES, Walker BD, Yu XG, Lichterfeld M. CD4+ T cells from elite controllers resist HIV-1 infection by selective upregulation of p21. J Clin Invest. 2011 Apr; 121(4):1549-60. PMID: 21403397; PMCID: PMC3069774.
  38. Vigneault F, Woods M, Buzon MJ, Li C, Pereyra F, Crosby SD, Rychert J, Church G, Martinez-Picado J, Rosenberg ES, Telenti A, Yu XG, Lichterfeld M. Transcriptional profiling of CD4 T cells identifies distinct subgroups of HIV-1 elite controllers. J Virol. 2011 Mar; 85(6):3015-9. PMID: 21177805; PMCID: PMC3067917.
  39. Yang Y, Huang J, Toth I, Lichterfeld M, Yu XG. Mutational escape in HIV-1 CTL epitopes leads to increased binding to inhibitory myelomonocytic MHC class I receptors. PLoS One. 2010; 5(12):e15084. PMID: 21170342; PMCID: PMC2999561.
  40. Huang J, Burke P, Yang Y, Seiss K, Beamon J, Cung T, Toth I, Pereyra F, Lichterfeld M, Yu XG. Soluble HLA-G inhibits myeloid dendritic cell function in HIV-1 infection by interacting with leukocyte immunoglobulin-like receptor B2. J Virol. 2010 Oct; 84(20):10784-91. PMID: 20702625; PMCID: PMC2950595.
  41. Williams K, Seiss K, Beamon J, Pereyra F, Rosenberg ES, Walker BD, Yu XG, Lichterfeld M. Epigenetic regulation of telomerase expression in HIV-1-specific CD8+ T cells. AIDS. 2010 Jul 31; 24(12):1964-6. PMID: 20588158; PMCID: PMC2924203.
  42. Huang J, Burke PS, Cung TD, Pereyra F, Toth I, Walker BD, Borges L, Lichterfeld M, Yu XG. Leukocyte immunoglobulin-like receptors maintain unique antigen-presenting properties of circulating myeloid dendritic cells in HIV-1-infected elite controllers. J Virol. 2010 Sep; 84(18):9463-71. PMID: 20631139; PMCID: PMC2937602.
  43. Huang J, Goedert JJ, Sundberg EJ, Cung TD, Burke PS, Martin MP, Preiss L, Lifson J, Lichterfeld M, Carrington M, Yu XG. HLA-B*35-Px-mediated acceleration of HIV-1 infection by increased inhibitory immunoregulatory impulses. J Exp Med. 2009 Dec 21; 206(13):2959-66. PMID: 20008523; PMCID: PMC2806456.
  44. Lichterfeld M, Ferraro MJ, Davis BT. High-dose daptomycin for the treatment of endocarditis caused by Staphylococcus aureus with intermediate susceptibility to glycopeptides. Int J Antimicrob Agents. 2010 Jan; 35(1):96. PMID: 19896341.
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  45. Lichterfeld M, Mou D, Cung TD, Williams KL, Waring MT, Huang J, Pereyra F, Trocha A, Freeman GJ, Rosenberg ES, Walker BD, Yu XG. Telomerase activity of HIV-1-specific CD8+ T cells: constitutive up-regulation in controllers and selective increase by blockade of PD ligand 1 in progressors. Blood. 2008 Nov 1; 112(9):3679-87. PMID: 18728248; PMCID: PMC2572795.
  46. Lichterfeld M, Kavanagh D, Williams KL, Mosa B, Mui S, Miura T, Allgaier R, Pereyra F, Trocha A, Feeney M, Gandhi R, Rosenberg E, Altfeld M, Allen T, Allen R, Walker B, Sundberg E, Yu XG. A Viral CTL escape mutation leading to ILT4-mediated functional inhibition of myelomonocytic cells. Journal of Experimental Medicine (in print). 2007; 204(12):2813-24.
  47. Lichterfeld M, Kavanagh DG, Williams KL, Moza B, Mui SK, Miura T, Sivamurthy R, Allgaier R, Pereyra F, Trocha A, Feeney M, Gandhi RT, Rosenberg ES, Altfeld M, Allen TM, Allen R, Walker BD, Sundberg EJ, Yu XG. A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells. J Exp Med. 2007 Nov 26; 204(12):2813-24. PMID: 18025130; PMCID: PMC2118510.
  48. Yu XG, Lichterfeld M, Williams KL, Martinez-Picado J, Walker BD. Random T-cell receptor recruitment in human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells from genetically identical twins infected with the same HIV-1 strain. J Virol. 2007 Nov; 81(22):12666-9. PMID: 17804503; PMCID: PMC2169022.
  49. Brainard DM, Tager AM, Misdraji J, Frahm N, Lichterfeld M, Draenert R, Brander C, Walker BD, Luster AD. Decreased CXCR3+ CD8 T cells in advanced human immunodeficiency virus infection suggest that a homing defect contributes to cytotoxic T-lymphocyte dysfunction. J Virol. 2007 Aug; 81(16):8439-50. PMID: 17553894; PMCID: PMC1951383.
  50. Streeck H, Lichterfeld M, Alter G, Meier A, Teigen N, Yassine-Diab B, Sidhu HK, Little S, Kelleher A, Routy JP, Rosenberg ES, Sekaly RP, Walker BD, Altfeld M. Recognition of a defined region within p24 gag by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles. J Virol. 2007 Jul; 81(14):7725-31. PMID: 17494064; PMCID: PMC1933382.
  51. Lichterfeld M, Yu XG, Mui SK, Williams KL, Trocha A, Brockman MA, Allgaier RL, Waring MT, Koibuchi T, Johnston MN, Cohen D, Allen TM, Rosenberg ES, Walker BD, Altfeld M. Selective depletion of high-avidity human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells after early HIV-1 infection. J Virol. 2007 Apr; 81(8):4199-214. PMID: 17287271; PMCID: PMC1866095.
  52. Yu XG, Lichterfeld M, Chetty S, Williams KL, Mui SK, Miura T, Frahm N, Feeney ME, Tang Y, Pereyra F, Labute MX, Pfafferott K, Leslie A, Crawford H, Allgaier R, Hildebrand W, Kaslow R, Brander C, Allen TM, Rosenberg ES, Kiepiela P, Vajpayee M, Goepfert PA, Altfeld M, Goulder PJ, Walker BD. Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypes. J Virol. 2007 Feb; 81(4):1619-31. PMID: 17121793; PMCID: PMC1797559.
  53. Altfeld M, Kalife ET, Qi Y, Streeck H, Lichterfeld M, Johnston MN, Burgett N, Swartz ME, Yang A, Alter G, Yu XG, Meier A, Rockstroh JK, Allen TM, Jessen H, Rosenberg ES, Carrington M, Walker BD. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1. PLoS Med. 2006 Oct; 3(10):e403. PMID: 17076553; PMCID: PMC1626551.
  54. Streeck H, Jessen H, Alter G, Teigen N, Waring MT, Jessen A, Stahmer I, van Lunzen J, Lichterfeld M, Gao X, Allen TM, Carrington M, Walker BD, Rockstroh JK, Altfeld M. Immunological and virological impact of highly active antiretroviral therapy initiated during acute HIV-1 infection. J Infect Dis. 2006 Sep 15; 194(6):734-9. PMID: 16941338.
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  55. Vogel M, Lichterfeld M, Kaufmann DE, Mui SK, Altfeld M, Voigt E, Ahlenstiel G, Kupfer B, Walker B, Spengler U, Rockstroh JK. Structured treatment interruptions following immediate initiation of HAART in eight patients with acute HIV-1 seroconversion. Eur J Med Res. 2006 Jul 31; 11(7):273-8. PMID: 16899420.
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  56. WALKER, Bruce YU, XG LICHTERFELD, M . TCR ALPHA AND BETA CHAIN SEQUENCES OF HIV-1-SPECIFIC AND HCV-SPECIFIC CD8+ T CELLS. 2006.
  57. Lichterfeld M, Williams KL, Mui SK, Shah SS, Mothe BR, Sette A, Kim A, Johnston MN, Burgett N, Frahm N, Cohen D, Brander C, Rosenberg ES, Walker BD, Altfeld M, Yu XG. T cell receptor cross-recognition of an HIV-1 CD8+ T cell epitope presented by closely related alleles from the HLA-A3 superfamily. Int Immunol. 2006 Jul; 18(7):1179-88. PMID: 16772368.
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  58. Frahm N, Kiepiela P, Adams S, Linde CH, Hewitt HS, Sango K, Feeney ME, Addo MM, Lichterfeld M, Lahaie MP, Pae E, Wurcel AG, Roach T, St John MA, Altfeld M, Marincola FM, Moore C, Mallal S, Carrington M, Heckerman D, Allen TM, Mullins JI, Korber BT, Goulder PJ, Walker BD, Brander C. Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes. Nat Immunol. 2006 Feb; 7(2):173-8. PMID: 16369537.
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  59. Allen TM, Yu XG, Kalife ET, Reyor LL, Lichterfeld M, John M, Cheng M, Allgaier RL, Mui S, Frahm N, Alter G, Brown NV, Johnston MN, Rosenberg ES, Mallal SA, Brander C, Walker BD, Altfeld M. De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection. J Virol. 2005 Oct; 79(20):12952-60. PMID: 16188997; PMCID: PMC1235830.
  60. Yu XG, Lichterfeld M, Perkins B, Kalife E, Mui S, Chen J, Cheng M, Kang W, Alter G, Brander C, Walker BD, Altfeld M. High degree of inter-clade cross-reactivity of HIV-1-specific T cell responses at the single peptide level. AIDS. 2005 Sep 23; 19(14):1449-56. PMID: 16135897.
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  61. Frahm N, Adams S, Kiepiela P, Linde CH, Hewitt HS, Lichterfeld M, Sango K, Brown NV, Pae E, Wurcel AG, Altfeld M, Feeney ME, Allen TM, Roach T, St John MA, Daar ES, Rosenberg E, Korber B, Marincola F, Walker BD, Goulder PJ, Brander C. HLA-B63 presents HLA-B57/B58-restricted cytotoxic T-lymphocyte epitopes and is associated with low human immunodeficiency virus load. J Virol. 2005 Aug; 79(16):10218-25. PMID: 16051815; PMCID: PMC1182636.
  62. Lichterfeld M, Pantaleo G, Altfeld M. Loss of HIV-1-specific T cell proliferation in chronic HIV-1 infection: cause or consequence of viral replication? AIDS. 2005 Jul 22; 19(11):1225-7. PMID: 15990577.
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  63. Alter G, Teigen N, Davis BT, Addo MM, Suscovich TJ, Waring MT, Streeck H, Johnston MN, Staller KD, Zaman MT, Yu XG, Lichterfeld M, Basgoz N, Rosenberg ES, Altfeld M. Sequential deregulation of NK cell subset distribution and function starting in acute HIV-1 infection. Blood. 2005 Nov 15; 106(10):3366-9. PMID: 16002429.
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  64. Koibuchi T, Allen TM, Lichterfeld M, Mui SK, O'Sullivan KM, Trocha A, Kalams SA, Johnson RP, Walker BD. Limited sequence evolution within persistently targeted CD8 epitopes in chronic human immunodeficiency virus type 1 infection. J Virol. 2005 Jul; 79(13):8171-81. PMID: 15956562; PMCID: PMC1143727.
  65. Lichterfeld M, Qurishi N, Hoffmann C, Hochdorfer B, Brockmeyer NH, Arasteh K, Mauss S, Rockstroh JK. Treatment of HIV-1-associated Kaposi's sarcoma with pegylated liposomal doxorubicin and HAART simultaneously induces effective tumor remission and CD4+ T cell recovery. Infection. 2005 Jun; 33(3):140-7. PMID: 15940415.
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  66. Lichterfeld M, Haas S, Fischer HP, Voigt E, Rockstroh JK, Spengler U. Liver histopathology in human immunodeficiency virus-hepatitis C virus co-infected patients with fatal liver disease. J Gastroenterol Hepatol. 2005 May; 20(5):739-45. PMID: 15853988.
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  67. Altfeld M, Allen TM, Kalife ET, Frahm N, Addo MM, Mothe BR, Rathod A, Reyor LL, Harlow J, Yu XG, Perkins B, Robinson LK, Sidney J, Alter G, Lichterfeld M, Sette A, Rosenberg ES, Goulder PJ, Brander C, Walker BD. The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design. J Virol. 2005 Apr; 79(8):5000-5. PMID: 15795285; PMCID: PMC1069570.
  68. Lichterfeld M, Schmeisser N, Qurishi N, Vogel M, Brackmann HH, Spengler U, Rockstroh JK. Clinical outcomes of HIV-HCV co-infection in a large cohort of hemophiliac patients. J Infect. 2005 Apr; 50(3):221-8. PMID: 15780416.
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  69. Lichterfeld M, Yu XG, Le Gall S, Altfeld M. Immunodominance of HIV-1-specific CD8(+) T-cell responses in acute HIV-1 infection: at the crossroads of viral and host genetics. Trends Immunol. 2005 Mar; 26(3):166-71. PMID: 15745859.
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  70. Yu XG, Lichterfeld M, Addo MM, Altfeld M. Regulatory and accessory HIV-1 proteins: potential targets for HIV-1 vaccines? Curr Med Chem. 2005; 12(6):741-7. PMID: 15790309.
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  71. Kaufmann DE, Lichterfeld M, Altfeld M, Addo MM, Johnston MN, Lee PK, Wagner BS, Kalife ET, Strick D, Rosenberg ES, Walker BD. Limited durability of viral control following treated acute HIV infection. PLoS Med. 2004 Nov; 1(2):e36. PMID: 15526059; PMCID: PMC524377.
  72. Alter G, Malenfant JM, Delabre RM, Burgett NC, Yu XG, Lichterfeld M, Zaunders J, Altfeld M. Increased natural killer cell activity in viremic HIV-1 infection. J Immunol. 2004 Oct 15; 173(8):5305-11. PMID: 15470077.
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  73. Lichterfeld M, Kaufmann DE, Yu XG, Mui SK, Addo MM, Johnston MN, Cohen D, Robbins GK, Pae E, Alter G, Wurcel A, Stone D, Rosenberg ES, Walker BD, Altfeld M. Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells. J Exp Med. 2004 Sep 20; 200(6):701-12. PMID: 15381726; PMCID: PMC2211961.
  74. Lichterfeld M, Yu XG, Cohen D, Addo MM, Malenfant J, Perkins B, Pae E, Johnston MN, Strick D, Allen TM, Rosenberg ES, Korber B, Walker BD, Altfeld M. HIV-1 Nef is preferentially recognized by CD8 T cells in primary HIV-1 infection despite a relatively high degree of genetic diversity. AIDS. 2004 Jul 2; 18(10):1383-92. PMID: 15199314.
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  75. Nischalke HD, Nattermann J, Lichterfeld M, Woitas RP, Rockstroh JK, Sauerbruch T, Spengler U. Rapid determination of the Delta32 deletion in the human CC-chemokine receptor 5 (CCR5) gene without DNA extraction by lightcycler real-time polymerase chain reaction. AIDS Res Hum Retroviruses. 2004 Jul; 20(7):750-4. PMID: 15307921.
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  76. Allen TM, Altfeld M, Yu XG, O'Sullivan KM, Lichterfeld M, Le Gall S, John M, Mothe BR, Lee PK, Kalife ET, Cohen DE, Freedberg KA, Strick DA, Johnston MN, Sette A, Rosenberg ES, Mallal SA, Goulder PJ, Brander C, Walker BD. Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection. J Virol. 2004 Jul; 78(13):7069-78. PMID: 15194783; PMCID: PMC421658.
  77. Kaufmann DE, Bailey PM, Sidney J, Wagner B, Norris PJ, Johnston MN, Cosimi LA, Addo MM, Lichterfeld M, Altfeld M, Frahm N, Brander C, Sette A, Walker BD, Rosenberg ES. Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides. J Virol. 2004 May; 78(9):4463-77. PMID: 15078927; PMCID: PMC387674.
  78. Yu XG, Addo MM, Perkins BA, Wej F, Rathod A, Geer SC, Parta M, Cohen D, Stone DR, Russell CJ, Tanzi G, Mei S, Wurcel AG, Frahm N, Lichterfeld M, Heath L, Mullins JI, Marincola F, Goulder PJ, Brander C, Allen T, Cao Y, Walker BD, Altfeld M. Differences in the expressed HLA class I alleles effect the differential clustering of HIV type 1-specific T cell responses in infected Chinese and caucasians. AIDS Res Hum Retroviruses. 2004 May; 20(5):557-64. PMID: 15186531.
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  79. Lichterfeld M, Yu XG, Waring MT, Mui SK, Johnston MN, Cohen D, Addo MM, Zaunders J, Alter G, Pae E, Strick D, Allen TM, Rosenberg ES, Walker BD, Altfeld M. HIV-1-specific cytotoxicity is preferentially mediated by a subset of CD8(+) T cells producing both interferon-gamma and tumor necrosis factor-alpha. Blood. 2004 Jul 15; 104(2):487-94. PMID: 15059848.
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  80. Tarrand JJ, Lichterfeld M, Warraich I, Luna M, Han XY, May GS, Kontoyiannis DP. Diagnosis of invasive septate mold infections. A correlation of microbiological culture and histologic or cytologic examination. Am J Clin Pathol. 2003 Jun; 119(6):854-8. PMID: 12817433.
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  81. Lichterfeld M, Nischalke HD, van Lunzen J, Söhne J, Schmeisser N, Woitas R, Sauerbruch T, Rockstroh JK, Spengler U. The tandem-repeat polymorphism of the DC-SIGNR gene does not affect the susceptibility to HIV infection and the progression to AIDS. Clin Immunol. 2003 Apr; 107(1):55-9. PMID: 12738250.
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  82. Lichterfeld M, Rockstroh JK. [Antiretroviral treatment of HIV infected patients]. Med Monatsschr Pharm. 2003 Apr; 26(4):111-21; quiz 121-2. PMID: 12722525.
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  83. Lichterfeld M, Wöhrmann A, Schmeisser N, Fätkenheuer G, Salzberger B, Wyen C, Schmitz K, Sauerbruch T, Rockstroh JK. Superior virological efficacy of ritonavir-boosted protease inhibitor regimens compared to single protease inhibitor therapy. Eur J Med Res. 2003 Feb 21; 8(2):56-60. PMID: 12626282.
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  84. Lichterfeld M, Fischer HP, Spengler U, Rockstroh JK. [Fatty liver and increased serum lactate in a woman with HIV]. Dtsch Med Wochenschr. 2003 Jan 17; 128(3):81-4. PMID: 12529837.
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  85. Rockstroh JK, Mudar M, Lichterfeld M, Nischalke HD, Klausen G, Gölz J, Dupke S, Notheis G, Stein L, Mauss S. Pilot study of interferon alpha high-dose induction therapy in combination with ribavirin for chronic hepatitis C in HIV-co-infected patients. AIDS. 2002 Oct 18; 16(15):2083-5. PMID: 12370510.
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  86. Lichterfeld M, Leifeld L, Nischalke HD, Rockstroh JK, Hess L, Sauerbruch T, Spengler U. Reduced CC chemokine receptor (CCR) 1 and CCR5 surface expression on peripheral blood T lymphocytes from patients with chronic hepatitis C infection. J Infect Dis. 2002 Jun 15; 185(12):1803-7. PMID: 12085329.
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  87. Spengler U, Lichterfeld M, Rockstroh JK. Antiretroviral drug toxicity -- a challenge for the hepatologist? J Hepatol. 2002 Feb; 36(2):283-94. PMID: 11830343.
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  88. Lichterfeld M, Nischalke HD, Bergmann F, Wiesel W, Rieke A, Theisen A, Fätkenheuer G, Oette M, Carls H, Fenske S, Nadler M, Knechten H, Wasmuth JC, Rockstroh JK. Long-term efficacy and safety of ritonavir/indinavir at 400/400 mg twice a day in combination with two nucleoside reverse transcriptase inhibitors as first line antiretroviral therapy. HIV Med. 2002 Jan; 3(1):37-43. PMID: 12059949.
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  89. Lichterfeld M, Lorenz C, Nischalke HD, Scheurlen C, Sauerbruch T, Rockstroh JK. Decreased prevalence of Helicobacter pylori infection in HIV patients with AIDS defining diseases. Z Gastroenterol. 2002 Jan; 40(1):11-4. PMID: 11803495.
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  90. Lichterfeld M, Martin S, Burkly L, Haas R, Kronenwett R. Mobilization of CD34+ haematopoietic stem cells is associated with a functional inactivation of the integrin very late antigen 4. Br J Haematol. 2000 Jul; 110(1):71-81. PMID: 10930981.
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  91. HAAS, Rainer KRONENWETT, Ralf LICHTERFELD, Mathias . ANTISENSE OLIGONUCLEOTIDE FOR INHIBITING THE EXPRESSION OF THE ADHESION MOLECULE VERY LATE ANTIGEN 4 (VLA-4) IN HUMAN CELLS . 2000.
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