Harvard Catalyst Profiles

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Jerome Elliot Groopman, M.D.

Title
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Department
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Mentoring
HIV-1 Tat Protein Mediated Endothelial Dysfunction in HIV Infection
Part Time/Continuation, 09/01/98 - 06/01/99
A Qualitative Study of the Pediatric-to-Adult Care Transition in Patients with Type I Diabetes
Summer, 04/02/12 - 08/15/12

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DA039566 (GROOPMAN, JEROME E) Aug 1, 2015 - Jun 30, 2020
    NIH/NIDA
    Novel Mechanisms of Disarming Anti-HIV Host Defenses by Methamphetamine
    Role: Principal Investigator
  2. R01DA036298 (GROOPMAN, JEROME E) Jul 1, 2013 - Mar 31, 2018
    NIH/NIDA
    Novel Strategies to Antagonize Cocaine-Enhanced HIV Pathobiology
    Role: Principal Investigator
  3. DP1DA026197 (GROOPMAN, JEROME E) Sep 5, 2008 - Jul 31, 2013
    NIH/NIDA
    Inhibition of HIV at the Immune Synapse Utilizing Novel Ligands and Receptors
    Role: Principal Investigator
  4. R01DA015008 (GROOPMAN, JEROME E) Sep 30, 2001 - Aug 31, 2007
    NIH/NIDA
    Pathogenesis of Hepatic Injury with HCV/HIV Coinfection
    Role: Principal Investigator
  5. R01HL061940 (GROOPMAN, JEROME E) Sep 20, 1998 - Jul 31, 2003
    NIH/NHLBI
    Functional Studies of HIV-Tat Effects on Endothelium
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hartzband P, Groopman J. Physician Burnout, Interrupted. N Engl J Med. 2020 Jun 25; 382(26):2485-2487. PMID: 32356624.
    Citations:    
  2. Lawson KS, Prasad A, Groopman JE. Methamphetamine Enhances HIV-1 Replication in CD4+ T-Cells via a Novel IL-1ß Auto-Regulatory Loop. Front Immunol. 2020; 11:136. PMID: 32117283.
    Citations:    
  3. Prasad A, Kulkarni R, Shrivastava A, Jiang S, Lawson K, Groopman JE. Methamphetamine functions as a novel CD4+ T-cell activator via the sigma-1 receptor to enhance HIV-1 infection. Sci Rep. 2019 01 30; 9(1):958. PMID: 30700725.
    Citations:    Fields:    
  4. Groopman J, Hartzband P. The Power of Regret. N Engl J Med. 2017 Oct 19; 377(16):1507-1509. PMID: 29045218.
    Citations: 2     Fields:    Translation:Humans
  5. Prasad A, Kulkarni R, Jiang S, Groopman JE. Cocaine Enhances DC to T-cell HIV-1 Transmission by Activating DC-SIGN/LARG/LSP1 Complex and Facilitating Infectious Synapse Formation. Sci Rep. 2017 01 17; 7:40648. PMID: 28094782.
    Citations: 1     Fields:    Translation:HumansCells
  6. Hartzband P, Groopman J. Medical Taylorism, Lean, and Toyota. N Engl J Med. 2016 05 19; 374(20):1994. PMID: 27192687.
    Citations:    Fields:    Translation:Humans
  7. Hartzband P, Groopman J. Medical Taylorism. N Engl J Med. 2016 Jan 14; 374(2):106-8. PMID: 26760082.
    Citations: 3     Fields:    Translation:Humans
  8. Shrivastava A, Prasad A, Kuzontkoski PM, Yu J, Groopman JE. Slit2N Inhibits Transmission of HIV-1 from Dendritic Cells to T-cells by Modulating Novel Cytoskeletal Elements. Sci Rep. 2015 Nov 19; 5:16833. PMID: 26582347.
    Citations: 5     Fields:    Translation:HumansCells
  9. Zhang X, Jiang S, Yu J, Kuzontkoski PM, Groopman JE. Cocaine enhances HIV-1 gp120-induced lymphatic endothelial dysfunction in the lung. Physiol Rep. 2015 Aug; 3(8). PMID: 26311830.
    Citations: 2     Fields:    
  10. Yu J, Zhang X, Kuzontkoski PM, Jiang S, Zhu W, Li DY, Groopman JE. Slit2N and Robo4 regulate lymphangiogenesis through the VEGF-C/VEGFR-3 pathway. Cell Commun Signal. 2014 Apr 07; 12:25. PMID: 24708522.
    Citations: 6     Fields:    Translation:HumansCells
  11. Prasad A, Shrivastava A, Papadopoulos E, Kuzontkoski PM, Reddy MV, Gillum AM, Kumar R, Reddy EP, Groopman JE. Combined administration of rituximab and on 013105 induces apoptosis in mantle cell lymphoma cells and reduces tumor burden in a mouse model of mantle cell lymphoma. Clin Cancer Res. 2013 Jan 01; 19(1):85-95. PMID: 23124440.
    Citations: 2     Fields:    Translation:AnimalsCells
  12. Prasad A, Kuzontkoski PM, Shrivastava A, Zhu W, Li DY, Groopman JE. Slit2N/Robo1 inhibit HIV-gp120-induced migration and podosome formation in immature dendritic cells by sequestering LSP1 and WASp. PLoS One. 2012; 7(10):e48854. PMID: 23119100.
    Citations: 11     Fields:    Translation:HumansCells
  13. Nagaraja T, Chen L, Balasubramanian A, Groopman JE, Ghoshal K, Jacob ST, Leask A, Brigstock DR, Anand AR, Ganju RK. Activation of the connective tissue growth factor (CTGF)-transforming growth factor ß 1 (TGF-ß 1) axis in hepatitis C virus-expressing hepatocytes. PLoS One. 2012; 7(10):e46526. PMID: 23056332.
    Citations: 5     Fields:    Translation:HumansCells
  14. Hartzband P, Groopman J. There is more to life than death. N Engl J Med. 2012 Sep 13; 367(11):987-9. PMID: 22970943.
    Citations: 4     Fields:    Translation:Humans
  15. Maor Y, Yu J, Kuzontkoski PM, Dezube BJ, Zhang X, Groopman JE. Cannabidiol inhibits growth and induces programmed cell death in kaposi sarcoma-associated herpesvirus-infected endothelium. Genes Cancer. 2012 Jul; 3(7-8):512-20. PMID: 23264851.
    Citations: 2     
  16. Groopman JE. Much progress, still many challenges. AIDS. 2012 Jun 19; 26(10):1197. PMID: 22706003.
    Citations:    Fields:    Translation:HumansCells
  17. Olnes MJ, Shenoy A, Weinstein B, Pfannes L, Loeliger K, Tucker Z, Tian X, Kwak M, Wilhelm F, Yong AS, Maric I, Maniar M, Scheinberg P, Groopman J, Young NS, Sloand EM. Directed therapy for patients with myelodysplastic syndromes (MDS) by suppression of cyclin D1 with ON 01910.Na. Leuk Res. 2012 Aug; 36(8):982-9. PMID: 22524974.
    Citations: 15     Fields:    Translation:HumansCellsCTClinical Trials
  18. Hartzband P, Groopman J. The new language of medicine. Obstet Gynecol. 2012 Feb; 119(2 Pt 1):369-70. PMID: 22270290.
    Citations: 1     Fields:    Translation:Humans
  19. Zhang X, Yu J, Kuzontkoski PM, Zhu W, Li DY, Groopman JE. Slit2/Robo4 signaling modulates HIV-1 gp120-induced lymphatic hyperpermeability. PLoS Pathog. 2012 Jan; 8(1):e1002461. PMID: 22241990.
    Citations: 17     Fields:    Translation:HumansCells
  20. Hartzband P, Groopman J. The new language of medicine. Minn Med. 2011 Dec; 94(12):36-7. PMID: 22372046.
    Citations:    Fields:    
  21. Hartzband P, Groopman J. The new language of medicine. N Engl J Med. 2011 Oct 13; 365(15):1372-3. PMID: 21995384.
    Citations: 4     Fields:    Translation:Humans
  22. Shrivastava A, Kuzontkoski PM, Groopman JE, Prasad A. Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy. Mol Cancer Ther. 2011 Jul; 10(7):1161-72. PMID: 21566064.
    Citations: 58     Fields:    Translation:HumansCells
  23. Groopman J. The peanut puzzle: could the conventional wisdom on children and allergies be wrong? New Yorker. 2011 Feb; 26-30. PMID: 21728267.
    Citations:    Translation:Humans
  24. Preet A, Qamri Z, Nasser MW, Prasad A, Shilo K, Zou X, Groopman JE, Ganju RK. Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non-small cell lung cancer growth and metastasis. Cancer Prev Res (Phila). 2011 Jan; 4(1):65-75. PMID: 21097714.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  25. Jiang S, Alberich-Jorda M, Zagozdzon R, Parmar K, Fu Y, Mauch P, Banu N, Makriyannis A, Tenen DG, Avraham S, Groopman JE, Avraham HK. Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization. Blood. 2011 Jan 20; 117(3):827-38. PMID: 21063029.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  26. Jiang S, Zagozdzon R, Jorda MA, Parmar K, Fu Y, Williams JS, Wood JA, Makriyannis A, Banu N, Avraham S, Groopman JE, Avraham HK. Endocannabinoids are expressed in bone marrow stromal niches and play a role in interactions of hematopoietic stem and progenitor cells with the bone marrow microenvironment. J Biol Chem. 2010 Nov 12; 285(46):35471-8. PMID: 20826813.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  27. Zhang X, Maor Y, Wang JF, Kunos G, Groopman JE. Endocannabinoid-like N-arachidonoyl serine is a novel pro-angiogenic mediator. Br J Pharmacol. 2010 Aug; 160(7):1583-94. PMID: 20649563.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  28. Groopman J. The plastic panic: how worried should we be about everyday chemicals? New Yorker. 2010 May; 26-31. PMID: 21695842.
    Citations:    Translation:PHPublic Health
  29. Hartzband P, Groopman J. Untangling the Web--patients, doctors, and the Internet. N Engl J Med. 2010 Mar 25; 362(12):1063-6. PMID: 20335581.
    Citations: 21     Fields:    Translation:Humans
  30. Hartzband P, Groopman J. Keeping the patient in the equation--humanism and health care reform. N Engl J Med. 2009 Aug 06; 361(6):554-5. PMID: 19657120.
    Citations: 7     Fields:    Translation:Humans
  31. Groopman J. Open channels: Do new cystic-fibrosis therapies hold the key to treating other genetic disorders? New Yorker. 2009 May 04; 30-4. PMID: 19408414.
    Citations: 1     Translation:Humans
  32. Groopman J, Hartzband P. Why 'quality' care is dangerous. Mo Med. 2009 May-Jun; 106(3):174-5. PMID: 22641911.
    Citations:    Fields:    Translation:Humans
  33. Groopman J. That buzzing sound: the mystery of tinnitus. New Yorker. 2009 Feb 09; 42-9. PMID: 19663045.
    Citations:    
  34. Prasad A, Park IW, Allen H, Zhang X, Reddy MV, Boominathan R, Reddy EP, Groopman JE. Styryl sulfonyl compounds inhibit translation of cyclin D1 in mantle cell lymphoma cells. Oncogene. 2009 Mar 26; 28(12):1518-28. PMID: 19198627.
    Citations: 26     Fields:    Translation:HumansCells
  35. Hartzband P, Groopman J. Other voices. Should money drive everything? Hosp Health Netw. 2009 Feb; 83(2):12. PMID: 19294970.
    Citations:    Fields:    Translation:Humans
  36. Hartzband P, Groopman J. Money and the changing culture of medicine. N Engl J Med. 2009 Jan 08; 360(2):101-3. PMID: 19129522.
    Citations: 3     Fields:    Translation:Humans
  37. Hartzband P, Groopman J. Off the record--avoiding the pitfalls of going electronic. N Engl J Med. 2008 Apr 17; 358(16):1656-8. PMID: 18420497.
    Citations: 32     Fields:    Translation:Humans
  38. Groopman J. Buying a cure: what business know-how can do for disease. New Yorker. 2008 Jan 28; 38-43. PMID: 18491420.
    Citations: 1     Translation:Humans
  39. Balasubramanian A, Groopman JE, Ganju RK. Underlying pathophysiology of HCV infection in HIV-positive drug users. J Addict Dis. 2008; 27(2):75-82. PMID: 18681194.
    Citations: 3     Fields:    Translation:Humans
  40. Groopman J. Crybabies: solving the colic conundrum. New Yorker. 2007 Sep 17; 46-54. PMID: 17891845.
    Citations:    Translation:Humans
  41. Zhang X, Wang JF, Kunos G, Groopman JE. Cannabinoid modulation of Kaposi's sarcoma-associated herpesvirus infection and transformation. Cancer Res. 2007 Aug 01; 67(15):7230-7. PMID: 17671191.
    Citations: 9     Fields:    Translation:HumansCells
  42. Preet A, Ganju RK, Groopman JE. Delta9-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo. Oncogene. 2008 Jan 10; 27(3):339-46. PMID: 17621270.
    Citations: 25     Fields:    Translation:AnimalsCells
  43. Park IW, Reddy MV, Reddy EP, Groopman JE. Evaluation of novel cell cycle inhibitors in mantle cell lymphoma. Oncogene. 2007 Aug 16; 26(38):5635-42. PMID: 17369860.
    Citations: 3     Fields:    Translation:HumansCells
  44. Groopman J. The right to a trial: Should dying patients have access to experimental drugs? New Yorker. 2006 Dec 18; 40-7. PMID: 17176539.
    Citations:    
  45. Balasubramanian A, Ganju RK, Groopman JE. Signal transducer and activator of transcription factor 1 mediates apoptosis induced by hepatitis C virus and HIV envelope proteins in hepatocytes. J Infect Dis. 2006 Sep 01; 194(5):670-81. PMID: 16897667.
    Citations: 19     Fields:    Translation:HumansCells
  46. Ghosh S, Preet A, Groopman JE, Ganju RK. Cannabinoid receptor CB2 modulates the CXCL12/CXCR4-mediated chemotaxis of T lymphocytes. Mol Immunol. 2006 Jul; 43(14):2169-79. PMID: 16503355.
    Citations: 42     Fields:    Translation:HumansCells
  47. Balasubramanian A, Munshi N, Koziel MJ, Hu Z, Liang TJ, Groopman JE, Ganju RK. Structural proteins of Hepatitis C virus induce interleukin 8 production and apoptosis in human endothelial cells. J Gen Virol. 2005 Dec; 86(Pt 12):3291-3301. PMID: 16298974.
    Citations: 10     Fields:    Translation:HumansCells
  48. Balasubramanian A, Koziel M, Groopman JE, Ganju RK. Molecular mechanism of hepatic injury in coinfection with hepatitis C virus and HIV. Clin Infect Dis. 2005 Jul 01; 41 Suppl 1:S32-7. PMID: 16265611.
    Citations: 14     Fields:    Translation:HumansCells
  49. Zhang X, Wang JF, Chandran B, Persaud K, Pytowski B, Fingeroth J, Groopman JE. Kaposi's sarcoma-associated herpesvirus activation of vascular endothelial growth factor receptor 3 alters endothelial function and enhances infection. J Biol Chem. 2005 Jul 15; 280(28):26216-24. PMID: 15878864.
    Citations: 10     Fields:    Translation:HumansCells
  50. Groopman JE. A strategy for hope: a commentary on necessary collusion. J Clin Oncol. 2005 May 01; 23(13):3151-2. PMID: 15860877.
    Citations: 2     Fields:    Translation:Humans
  51. Zhang X, Groopman JE, Wang JF. Extracellular matrix regulates endothelial functions through interaction of VEGFR-3 and integrin alpha5beta1. J Cell Physiol. 2005 Jan; 202(1):205-14. PMID: 15389531.
    Citations: 32     Fields:    Translation:HumansCells
  52. Groopman J. A great case. N Engl J Med. 2004 Nov 11; 351(20):2043-5. PMID: 15537903.
    Citations: 1     Fields:    Translation:Humans
  53. Koenig HG, Groopman J. God at the bedside. N Engl J Med. 2004 Jul 08; 351(2):192-3; author reply 192-3. PMID: 15247363.
    Citations:    Fields:    Translation:Humans
  54. Wang JF, Zhang X, Groopman JE. Activation of vascular endothelial growth factor receptor-3 and its downstream signaling promote cell survival under oxidative stress. J Biol Chem. 2004 Jun 25; 279(26):27088-97. PMID: 15102829.
    Citations: 26     Fields:    Translation:HumansCells
  55. Groopman J. God at the bedside. N Engl J Med. 2004 Mar 18; 350(12):1176-8. PMID: 15028822.
    Citations: 2     Fields:    Translation:Humans
  56. Munshi N, Balasubramanian A, Koziel M, Ganju RK, Groopman JE. Hepatitis C and human immunodeficiency virus envelope proteins cooperatively induce hepatocytic apoptosis via an innocent bystander mechanism. J Infect Dis. 2003 Oct 15; 188(8):1192-204. PMID: 14551890.
    Citations: 40     Fields:    Translation:HumansCells
  57. Balasubramanian A, Ganju RK, Groopman JE. Hepatitis C virus and HIV envelope proteins collaboratively mediate interleukin-8 secretion through activation of p38 MAP kinase and SHP2 in hepatocytes. J Biol Chem. 2003 Sep 12; 278(37):35755-66. PMID: 12824191.
    Citations: 31     Fields:    Translation:HumansCells
  58. Choe EY, Schoenberger ES, Groopman JE, Park IW. HIV Nef inhibits T cell migration. J Biol Chem. 2002 Nov 29; 277(48):46079-84. PMID: 12354773.
    Citations: 23     Fields:    Translation:HumansCells
  59. Tulpule A, Groopman J, Saville MW, Harrington W, Friedman-Kien A, Espina BM, Garces C, Mantelle L, Mettinger K, Scadden DT, Gill PS. Multicenter trial of low-dose paclitaxel in patients with advanced AIDS-related Kaposi sarcoma. Cancer. 2002 Jul 01; 95(1):147-54. PMID: 12115328.
    Citations: 21     Fields:    Translation:HumansCTClinical Trials
  60. Miles SA, Dezube BJ, Lee JY, Krown SE, Fletcher MA, Saville MW, Kaplan L, Groopman J, Scadden DT, Cooley T, Von Roenn J, Friedman-Kien A. Antitumor activity of oral 9-cis-retinoic acid in HIV-associated Kaposi's sarcoma. AIDS. 2002 Feb 15; 16(3):421-9. PMID: 11834954.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  61. Schwarz KB, Kew M, Klein A, Abrams RA, Sitzmann J, Jones L, Sharma S, Britton RS, Di Bisceglie AM, Groopman J. Increased hepatic oxidative DNA damage in patients with hepatocellular carcinoma. Dig Dis Sci. 2001 Oct; 46(10):2173-8. PMID: 11680593.
    Citations: 9     Fields:    Translation:Humans
  62. Wang JF, Zhang XF, Groopman JE. Stimulation of beta 1 integrin induces tyrosine phosphorylation of vascular endothelial growth factor receptor-3 and modulates cell migration. J Biol Chem. 2001 Nov 09; 276(45):41950-7. PMID: 11553610.
    Citations: 22     Fields:    Translation:Cells
  63. Park IW, Ullrich CK, Schoenberger E, Ganju RK, Groopman JE. HIV-1 Tat induces microvascular endothelial apoptosis through caspase activation. J Immunol. 2001 Sep 01; 167(5):2766-71. PMID: 11509621.
    Citations: 18     Fields:    Translation:HumansCells
  64. Zhang XF, Wang JF, Matczak E, Proper JA, Groopman JE. Janus kinase 2 is involved in stromal cell-derived factor-1alpha-induced tyrosine phosphorylation of focal adhesion proteins and migration of hematopoietic progenitor cells. Blood. 2001 Jun 01; 97(11):3342-8. PMID: 11369622.
    Citations: 44     Fields:    Translation:HumansCells
  65. Yang YM, Hatch WC, Liu ZY, Du B, Groopman JE. Beta-chemokine induction of activation protein-1 and cyclic AMP responsive element activation in human myeloid cells. Cell Growth Differ. 2001 Apr; 12(4):211-21. PMID: 11331250.
    Citations: 1     Fields:    Translation:HumansCells
  66. Park IW, Wang JF, Groopman JE. HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes. Blood. 2001 Jan 15; 97(2):352-8. PMID: 11154208.
    Citations: 39     Fields:    Translation:HumansCells
  67. Duvic M, Friedman-Kien AE, Looney DJ, Miles SA, Myskowski PL, Scadden DT, Von Roenn J, Galpin JE, Groopman J, Loewen G, Stevens V, Truglia JA, Yocum RC. Topical treatment of cutaneous lesions of acquired immunodeficiency syndrome-related Kaposi sarcoma using alitretinoin gel: results of phase 1 and 2 trials. Arch Dermatol. 2000 Dec; 136(12):1461-9. PMID: 11115156.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  68. Ullrich CK, Groopman JE, Ganju RK. HIV-1 gp120- and gp160-induced apoptosis in cultured endothelial cells is mediated by caspases. Blood. 2000 Aug 15; 96(4):1438-42. PMID: 10942389.
    Citations: 39     Fields:    Translation:HumansCells
  69. Ganju RK, Brubaker SA, Chernock RD, Avraham S, Groopman JE. Beta-chemokine receptor CCR5 signals through SHP1, SHP2, and Syk. J Biol Chem. 2000 Jun 09; 275(23):17263-8. PMID: 10747947.
    Citations: 21     Fields:    Translation:HumansCells
  70. Wang JF, Park IW, Groopman JE. Stromal cell-derived factor-1alpha stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: roles of phosphoinositide-3 kinase and protein kinase C. Blood. 2000 Apr 15; 95(8):2505-13. PMID: 10753828.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  71. Venkatakrishnan G, Salgia R, Groopman JE. Chemokine receptors CXCR-1/2 activate mitogen-activated protein kinase via the epidermal growth factor receptor in ovarian cancer cells. J Biol Chem. 2000 Mar 10; 275(10):6868-75. PMID: 10702246.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  72. Groopman J. Medicine on Mars. New Yorker. 2000 Feb 14; 75(46):36-41. PMID: 11543428.
    Citations:    Translation:Humans
  73. Munshi N, Groopman JE, Gill PS, Ganju RK. c-Src mediates mitogenic signals and associates with cytoskeletal proteins upon vascular endothelial growth factor stimulation in Kaposi's sarcoma cells. J Immunol. 2000 Feb 01; 164(3):1169-74. PMID: 10640727.
    Citations: 7     Fields:    Translation:HumansCells
  74. Munshi N, Ganju RK, Avraham S, Mesri EA, Groopman JE. Kaposi's sarcoma-associated herpesvirus-encoded G protein-coupled receptor activation of c-jun amino-terminal kinase/stress-activated protein kinase and lyn kinase is mediated by related adhesion focal tyrosine kinase/proline-rich tyrosine kinase 2. J Biol Chem. 1999 Nov 05; 274(45):31863-7. PMID: 10542211.
    Citations: 13     Fields:    Translation:HumansCells
  75. Park IW, Wang JF, Groopman JE. Expression and utilization of co-receptors in HIV and simian immunodeficiency virus infection of megakaryocytes. AIDS. 1999 Oct 22; 13(15):2023-32. PMID: 10546854.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  76. Groopman JE, Itri LM. Chemotherapy-induced anemia in adults: incidence and treatment. J Natl Cancer Inst. 1999 Oct 06; 91(19):1616-34. PMID: 10511589.
    Citations: 131     Fields:    Translation:Humans
  77. Park IW, Koziel H, Hatch W, Li X, Du B, Groopman JE. CD4 receptor-dependent entry of human immunodeficiency virus type-1 env-pseudotypes into CCR5-, CCR3-, and CXCR4-expressing human alveolar macrophages is preferentially mediated by the CCR5 coreceptor. Am J Respir Cell Mol Biol. 1999 May; 20(5):864-71. PMID: 10226056.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  78. Dutt P, Wang JF, Groopman JE. Stromal cell-derived factor-1 alpha and stem cell factor/kit ligand share signaling pathways in hemopoietic progenitors: a potential mechanism for cooperative induction of chemotaxis. J Immunol. 1998 Oct 01; 161(7):3652-8. PMID: 9759889.
    Citations: 36     Fields:    Translation:HumansCells
  79. Ganju RK, Brubaker SA, Meyer J, Dutt P, Yang Y, Qin S, Newman W, Groopman JE. The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways. J Biol Chem. 1998 Sep 04; 273(36):23169-75. PMID: 9722546.
    Citations: 142     Fields:    Translation:HumansAnimalsCells
  80. Wang JF, Liu ZY, Groopman JE. The alpha-chemokine receptor CXCR4 is expressed on the megakaryocytic lineage from progenitor to platelets and modulates migration and adhesion. Blood. 1998 Aug 01; 92(3):756-64. PMID: 9680341.
    Citations: 32     Fields:    Translation:HumansCells
  81. Ganju RK, Munshi N, Nair BC, Liu ZY, Gill P, Groopman JE. Human immunodeficiency virus tat modulates the Flk-1/KDR receptor, mitogen-activated protein kinases, and components of focal adhesion in Kaposi's sarcoma cells. J Virol. 1998 Jul; 72(7):6131-7. PMID: 9621077.
    Citations: 26     Fields:    Translation:HumansCells
  82. Landrigan PJ, Carlson JE, Bearer CF, Cranmer JS, Bullard RD, Etzel RA, Groopman J, McLachlan JA, Perera FP, Reigart JR, Robison L, Schell L, Suk WA. Children's health and the environment: a new agenda for prevention research. Environ Health Perspect. 1998 Jun; 106 Suppl 3:787-94. PMID: 9646038.
    Citations: 24     Fields:    Translation:HumansPHPublic Health
  83. Hatch WC, Ganju RK, Hiregowdara D, Avraham S, Groopman JE. The related adhesion focal tyrosine kinase (RAFTK) is tyrosine phosphorylated and participates in colony-stimulating factor-1/macrophage colony-stimulating factor signaling in monocyte-macrophages. Blood. 1998 May 15; 91(10):3967-73. PMID: 9573036.
    Citations: 7     Fields:    Translation:HumansCells
  84. Groopman JE. Fatigue in cancer and HIV/AIDS. Oncology (Williston Park). 1998 Mar; 12(3):335-44; discussion 345-6, 351. PMID: 9534184.
    Citations: 7     Fields:    Translation:Humans
  85. Ganju RK, Dutt P, Wu L, Newman W, Avraham H, Avraham S, Groopman JE. Beta-chemokine receptor CCR5 signals via the novel tyrosine kinase RAFTK. Blood. 1998 Feb 01; 91(3):791-7. PMID: 9446638.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  86. Wang JF, Ganju RK, Liu ZY, Avraham H, Avraham S, Groopman JE. Signal transduction in human hematopoietic cells by vascular endothelial growth factor related protein, a novel ligand for the FLT4 receptor. Blood. 1997 Nov 01; 90(9):3507-15. PMID: 9345034.
    Citations: 1     Fields:    Translation:HumansCells
  87. Liu ZY, Ganju RK, Wang JF, Schweitzer K, Weksler B, Avraham S, Groopman JE. Characterization of signal transduction pathways in human bone marrow endothelial cells. Blood. 1997 Sep 15; 90(6):2253-9. PMID: 9310476.
    Citations: 9     Fields:    Translation:HumansCells
  88. Groopman JE. Impact of transfusion on viral load in human immunodeficiency virus infection. Semin Hematol. 1997 Jul; 34(3 Suppl 2):27-33. PMID: 9253781.
    Citations: 1     Fields:    Translation:HumansCellsCTClinical Trials
  89. Macé K, Aguilar F, Wang JS, Vautravers P, Gómez-Lechón M, Gonzalez FJ, Groopman J, Harris CC, Pfeifer AM. Aflatoxin B1-induced DNA adduct formation and p53 mutations in CYP450-expressing human liver cell lines. Carcinogenesis. 1997 Jul; 18(7):1291-7. PMID: 9230270.
    Citations: 23     Fields:    Translation:HumansCells
  90. Hatch WC, Freedman AR, Boldt-Houle DM, Groopman JE, Terwilliger EF. Differential effects of interleukin-13 on cytomegalovirus and human immunodeficiency virus infection in human alveolar macrophages. Blood. 1997 May 01; 89(9):3443-50. PMID: 9129052.
    Citations: 7     Fields:    Translation:HumansCells
  91. Inouye RT, Du B, Boldt-Houle D, Ferrante A, Park IW, Hammer SM, Duan L, Groopman JE, Pomerantz RJ, Terwilliger EF. Potent inhibition of human immunodeficiency virus type 1 in primary T cells and alveolar macrophages by a combination anti-Rev strategy delivered in an adeno-associated virus vector. J Virol. 1997 May; 71(5):4071-8. PMID: 9094685.
    Citations: 5     Fields:    Translation:HumansCells
  92. Liu ZY, Ganju RK, Wang JF, Ona MA, Hatch WC, Zheng T, Avraham S, Gill P, Groopman JE. Cytokine signaling through the novel tyrosine kinase RAFTK in Kaposi's sarcoma cells. J Clin Invest. 1997 Apr 01; 99(7):1798-804. PMID: 9120025.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  93. Ganju RK, Hatch WC, Avraham H, Ona MA, Druker B, Avraham S, Groopman JE. RAFTK, a novel member of the focal adhesion kinase family, is phosphorylated and associates with signaling molecules upon activation of mature T lymphocytes. J Exp Med. 1997 Mar 17; 185(6):1055-63. PMID: 9091579.
    Citations: 18     Fields:    Translation:HumansCells
  94. Zrihan-Licht S, Lim J, Keydar I, Sliwkowski MX, Groopman JE, Avraham H. Association of csk-homologous kinase (CHK) (formerly MATK) with HER-2/ErbB-2 in breast cancer cells. J Biol Chem. 1997 Jan 17; 272(3):1856-63. PMID: 8999872.
    Citations: 10     Fields:    Translation:HumansCells
  95. Astier A, Avraham H, Manie SN, Groopman J, Canty T, Avraham S, Freedman AS. The related adhesion focal tyrosine kinase is tyrosine-phosphorylated after beta1-integrin stimulation in B cells and binds to p130cas. J Biol Chem. 1997 Jan 03; 272(1):228-32. PMID: 8995252.
    Citations: 52     Fields:    Translation:HumansCells
  96. Chen J, Herceg-Harjacek L, Groopman JE, Grabarek J. Regulation of platelet activation in vitro by the c-Mpl ligand, thrombopoietin. Blood. 1995 Dec 01; 86(11):4054-62. PMID: 7492761.
    Citations: 8     Fields:    Translation:HumansCells
  97. Avraham S, London R, Fu Y, Ota S, Hiregowdara D, Li J, Jiang S, Pasztor LM, White RA, Groopman JE, et al. Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain. J Biol Chem. 1995 Nov 17; 270(46):27742-51. PMID: 7499242.
    Citations: 73     Fields:    Translation:HumansAnimalsCells
  98. Banu N, Wang JF, Deng B, Groopman JE, Avraham H. Modulation of megakaryocytopoiesis by thrombopoietin: the c-Mpl ligand. Blood. 1995 Aug 15; 86(4):1331-8. PMID: 7632939.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  99. Ellis MH, Avraham H, Groopman JE. The regulation of megakaryocytopoiesis. Blood Rev. 1995 Mar; 9(1):1-6. PMID: 7795420.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  100. Jiang S, Levine JD, Fu Y, Deng B, London R, Groopman JE, Avraham H. Cytokine production by primary bone marrow megakaryocytes. Blood. 1994 Dec 15; 84(12):4151-6. PMID: 7527669.
    Citations: 11     Fields:    Translation:HumansCells
  101. Yamaguchi K, Groopman JE, Byrn RA. The regulation of HIV by retinoic acid correlates with cellular expression of the retinoic acid receptors. AIDS. 1994 Dec; 8(12):1675-82. PMID: 7888116.
    Citations: 9     Fields:    Translation:HumansCells
  102. Roberts MR, Qin L, Zhang D, Smith DH, Tran AC, Dull TJ, Groopman JE, Capon DJ, Byrn RA, Finer MH. Targeting of human immunodeficiency virus-infected cells by CD8+ T lymphocytes armed with universal T-cell receptors. Blood. 1994 Nov 01; 84(9):2878-89. PMID: 7949163.
    Citations: 32     Fields:    Translation:AnimalsCells
  103. Groopman JE. Thrombopoiesis. Capturing the unicorn. Curr Biol. 1994 Nov 01; 4(11):1016-8. PMID: 7874483.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  104. Grabarek J, Groopman JE, Lyles YR, Jiang S, Bennett L, Zsebo K, Avraham H. Human kit ligand (stem cell factor) modulates platelet activation in vitro. J Biol Chem. 1994 Aug 26; 269(34):21718-24. PMID: 7520441.
    Citations: 3     Fields:    Translation:HumansCells
  105. Papp B, Zhang D, Groopman JE, Byrn RA. Stimulation of human immunodeficiency virus type 1 expression by ceramide. AIDS Res Hum Retroviruses. 1994 Jul; 10(7):775-80. PMID: 7986582.
    Citations: 1     Fields:    Translation:HumansCells
  106. Avraham H, Banu N, Scadden DT, Abraham J, Groopman JE. Modulation of megakaryocytopoiesis by human basic fibroblast growth factor. Blood. 1994 Apr 15; 83(8):2126-32. PMID: 8161781.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  107. Scadden DT, Wang A, Zsebo KM, Groopman JE. In vitro effects of stem-cell factor or interleukin-3 on myelosuppression associated with AIDS. AIDS. 1994 Feb; 8(2):193-6. PMID: 7519020.
    Citations: 2     Fields:    Translation:HumansCells
  108. Bennett BD, Cowley S, Jiang S, London R, Deng B, Grabarek J, Groopman JE, Goeddel DV, Avraham H. Identification and characterization of a novel tyrosine kinase from megakaryocytes. J Biol Chem. 1994 Jan 14; 269(2):1068-74. PMID: 8288563.
    Citations: 16     Fields:    Translation:HumansCells
  109. Kunzi MS, Groopman JE. Identification of a novel human immunodeficiency virus strain cytopathic to megakaryocytic cells. Blood. 1993 Jun 15; 81(12):3336-42. PMID: 8507871.
    Citations: 4     Fields:    Translation:HumansCells
  110. Avraham H, Cowley S, Chi SY, Jiang S, Groopman JE. Characterization of adhesive interactions between human endothelial cells and megakaryocytes. J Clin Invest. 1993 Jun; 91(6):2378-84. PMID: 8514851.
    Citations: 13     Fields:    Translation:HumansCells
  111. Fischl MA, Krown SE, O'Boyle KP, Mitsuyasu R, Miles S, Wernz JC, Volberding PA, Kahn J, Groopman JE, Feinberg J, et al. Weekly doxorubicin in the treatment of patients with AIDS-related Kaposi's sarcoma. AIDS Clinical Trials Group. J Acquir Immune Defic Syndr (1988). 1993 Mar; 6(3):259-64. PMID: 8450401.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  112. Allan JD, Connolly KJ, Fitch H, Jackson-Pope L, McLaren C, Canetta R, Groopman JE. Long-term follow-up of didanosine administered orally twice daily to patients with advanced human immunodeficiency virus infection and hematologic intolerance of zidovudine. Clin Infect Dis. 1993 Feb; 16 Suppl 1:S46-51. PMID: 8425019.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  113. Groopman JE. The use of growth hematopoietic factors in AIDS. Pathol Biol (Paris). 1992 Nov; 39(9):874-5. PMID: 1371606.
    Citations:    Fields:    Translation:HumansCells
  114. Avraham H, Scadden DT, Chi S, Broudy VC, Zsebo KM, Groopman JE. Interaction of human bone marrow fibroblasts with megakaryocytes: role of the c-kit ligand. Blood. 1992 Oct 01; 80(7):1679-84. PMID: 1382698.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  115. Groopman JE, Molina JM. Nucleoside therapy for HIV infection--some answers, many questions. N Engl J Med. 1992 Aug 27; 327(9):639-41. PMID: 1640958.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  116. Groopman JE, Feder D. Hematopoietic growth factors in AIDS. Semin Oncol. 1992 Aug; 19(4):408-14. PMID: 1380730.
    Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
  117. Cowley SA, Groopman JE, Avraham H. Effects of transforming growth factor beta on megakaryocytic cell fusion and endomitosis. Int J Cell Cloning. 1992 Jul; 10(4):223-31. PMID: 1645030.
    Citations: 1     Fields:    Translation:HumansCells
  118. Scadden DT, Wang Z, Groopman JE. Quantitation of plasma human immunodeficiency virus type 1 RNA by competitive polymerase chain reaction. J Infect Dis. 1992 Jun; 165(6):1119-23. PMID: 1583331.
    Citations: 16     Fields:    Translation:HumansCells
  119. Avraham H, Vannier E, Chi SY, Dinarello CA, Groopman JE. Cytokine gene expression and synthesis by human megakaryocytic cells. Int J Cell Cloning. 1992 Mar; 10(2):70-9. PMID: 1545152.
    Citations: 4     Fields:    Translation:HumansCells
  120. Avraham H, Vannier E, Cowley S, Jiang SX, Chi S, Dinarello CA, Zsebo KM, Groopman JE. Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells. Blood. 1992 Jan 15; 79(2):365-71. PMID: 1370386.
    Citations: 19     Fields:    Translation:HumansCells
  121. Levine JD, Allan JD, Tessitore JH, Falcone N, Galasso F, Israel RJ, Groopman JE. Recombinant human granulocyte-macrophage colony-stimulating factor ameliorates zidovudine-induced neutropenia in patients with acquired immunodeficiency syndrome (AIDS)/AIDS-related complex. Blood. 1991 Dec 15; 78(12):3148-54. PMID: 1742482.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  122. Hodges TL, Kahn JO, Kaplan LD, Groopman JE, Volberding PA, Amman AJ, Arri CJ, Bouvier LM, Mordenti J, Izu AE, et al. Phase 1 study of recombinant human CD4-immunoglobulin G therapy of patients with AIDS and AIDS-related complex. Antimicrob Agents Chemother. 1991 Dec; 35(12):2580-6. PMID: 1810192.
    Citations: 8     Fields:    Translation:HumansCellsCTClinical Trials
  123. Puisieux A, Lim S, Groopman J, Ozturk M. Selective targeting of p53 gene mutational hotspots in human cancers by etiologically defined carcinogens. Cancer Res. 1991 Nov 15; 51(22):6185-9. PMID: 1933877.
    Citations: 33     Fields:    Translation:HumansCells
  124. Connolly KJ, Allan JD, Fitch H, Jackson-Pope L, McLaren C, Canetta R, Groopman JE. Phase I study of 2'-3'-dideoxyinosine administered orally twice daily to patients with AIDS or AIDS-related complex and hematologic intolerance to zidovudine. Am J Med. 1991 Nov; 91(5):471-8. PMID: 1659189.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  125. Huberman M, Bering H, Fallon B, Tessitore J, Sonnenborn H, Paul S, Zeffren J, Levitt D, Groopman J. A phase I study of an outpatient regimen of recombinant human interleukin-2 and alpha-2a-interferon in patients with solid tumors. Cancer. 1991 Oct 15; 68(8):1708-13. PMID: 1913512.
    Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
  126. Molina JM, Ferriani R, Amirault C, Groopman JE. Purified recombinant CD4 inhibits HIV-1 infection of peripheral blood macrophages. Pathol Biol (Paris). 1991 Oct; 39(8):754-8. PMID: 1762833.
    Citations:    Fields:    Translation:HumansCells
  127. Sakaguchi M, Zenzie-Gregory B, Groopman JE, Smale ST, Kim SY. Alternative pathway for induction of human immunodeficiency virus gene expression: involvement of the general transcription machinery. J Virol. 1991 Oct; 65(10):5448-56. PMID: 1895393.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  128. Scadden DT, Feder D, Groopman JE. Scratching the surface. Curr Biol. 1991 Oct; 1(5):301-3. PMID: 15336104.
    Citations:    Fields:    
  129. Scadden DT, Bering HA, Levine JD, Bresnahan J, Evans L, Epstein C, Groopman JE. Granulocyte-macrophage colony-stimulating factor mitigates the neutropenia of combined interferon alfa and zidovudine treatment of acquired immune deficiency syndrome-associated Kaposi's sarcoma. J Clin Oncol. 1991 May; 9(5):802-8. PMID: 2016623.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  130. Groopman JE. Treatment of AIDS with combinations of antiretroviral agents: a summary. Am J Med. 1991 Apr 10; 90(4A):27S-30S. PMID: 2018049.
    Citations:    Fields:    Translation:HumansCells
  131. Groopman JE. Antiretroviral therapy and immunomodulators in patients with AIDS. Am J Med. 1991 Apr 10; 90(4A):18S-21S. PMID: 2018046.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  132. Groopman JE. The challenge of combination antiretroviral therapy for AIDS. An introduction. Am J Med. 1991 Apr 10; 90(4A):1S. PMID: 2018044.
    Citations:    Fields:    Translation:Humans
  133. Groopman JE. AIDS. Of mice, monkeys and men. Nature. 1991 Feb 14; 349(6310):568-9. PMID: 2000132.
    Citations:    Fields:    Translation:HumansAnimalsCells
  134. Sakaguchi M, Sato T, Groopman JE. Human immunodeficiency virus infection of megakaryocytic cells. Blood. 1991 Feb 01; 77(3):481-5. PMID: 1991165.
    Citations: 13     Fields:    Translation:HumansCells
  135. Evans LM, Itri LM, Campion M, Wyler-Plaut R, Krown SE, Groopman JE, Goldsweig H, Volberding PA, West SB, Mitsuyasu RT, et al. Interferon-alpha 2a in the treatment of acquired immunodeficiency syndrome-related Kaposi's sarcoma. J Immunother (1991). 1991 Feb; 10(1):39-50. PMID: 1826454.
    Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
  136. Scadden DT, Bering HA, Levine JD, Bresnahan J, Evans L, Epstein C, Groopman JE. GM-CSF as an alternative to dose modification of the combination zidovudine and interferon-alpha in the treatment of AIDS-associated Kaposi's sarcoma. Am J Clin Oncol. 1991; 14 Suppl 1:S40-4. PMID: 2048563.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  137. Molina JM, Scadden DT, Sakaguchi M, Fuller B, Woon A, Groopman JE. Lack of evidence for infection of or effect on growth of hematopoietic progenitor cells after in vivo or in vitro exposure to human immunodeficiency virus. Blood. 1990 Dec 15; 76(12):2476-82. PMID: 2265244.
    Citations: 20     Fields:    Translation:HumansCells
  138. Sekigawa I, Chamow SM, Groopman JE, Byrn RA. CD4 immunoadhesin, but not recombinant soluble CD4, blocks syncytium formation by human immunodeficiency virus type 2-infected lymphoid cells. J Virol. 1990 Oct; 64(10):5194-8. PMID: 2398542.
    Citations: 14     Fields:    Translation:HumansCells
  139. Groopman JE. Management of the hematologic complications of human immunodeficiency virus infection. Rev Infect Dis. 1990 Sep-Oct; 12(5):931-7. PMID: 2237134.
    Citations: 4     Fields:    Translation:Humans
  140. Groopman JE. Current advances in the diagnosis and treatment of AIDS: an introduction. Rev Infect Dis. 1990 Sep-Oct; 12(5):908-11. PMID: 2237132.
    Citations: 1     Fields:    Translation:Humans
  141. Ikeuchi K, Kim S, Byrn RA, Goldring SR, Groopman JE. Infection of nonlymphoid cells by human immunodeficiency virus type 1 or type 2. J Virol. 1990 Sep; 64(9):4226-31. PMID: 2384919.
    Citations: 11     Fields:    Translation:HumansCells
  142. Scadden DT, Zeira M, Woon A, Wang Z, Schieve L, Ikeuchi K, Lim B, Groopman JE. Human immunodeficiency virus infection of human bone marrow stromal fibroblasts. Blood. 1990 Jul 15; 76(2):317-22. PMID: 1695109.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  143. Groopman JE. Granulocyte-macrophage colony-stimulating factor in human immunodeficiency virus disease. Semin Hematol. 1990 Jul; 27(3 Suppl 3):8-14. PMID: 2198662.
    Citations: 4     Fields:    Translation:HumansAnimals
  144. Groopman JE. Zidovudine intolerance. Rev Infect Dis. 1990 Jul-Aug; 12 Suppl 5:S500-6. PMID: 2201071.
    Citations: 7     Fields:    Translation:Humans
  145. Molina JM, Scadden DT, Amirault C, Woon A, Vannier E, Dinarello CA, Groopman JE. Human immunodeficiency virus does not induce interleukin-1, interleukin-6, or tumor necrosis factor in mononuclear cells. J Virol. 1990 Jun; 64(6):2901-6. PMID: 2335821.
    Citations: 28     Fields:    Translation:HumansCells
  146. Fischl M, Galpin JE, Levine JD, Groopman JE, Henry DH, Kennedy P, Miles S, Robbins W, Starrett B, Zalusky R, et al. Recombinant human erythropoietin for patients with AIDS treated with zidovudine. N Engl J Med. 1990 May 24; 322(21):1488-93. PMID: 2186273.
    Citations: 29     Fields:    Translation:HumansCTClinical Trials
  147. Molina JM, Schindler R, Ferriani R, Sakaguchi M, Vannier E, Dinarello CA, Groopman JE. Production of cytokines by peripheral blood monocytes/macrophages infected with human immunodeficiency virus type 1 (HIV-1). J Infect Dis. 1990 May; 161(5):888-93. PMID: 2182729.
    Citations: 18     Fields:    Translation:HumansCells
  148. Zeira M, Byrn RA, Groopman JE. Inhibition of serum-enhanced HIV-1 infection of U937 monocytoid cells by recombinant soluble CD4 and anti-CD4 monoclonal antibody. AIDS Res Hum Retroviruses. 1990 May; 6(5):629-39. PMID: 2361075.
    Citations: 10     Fields:    Translation:HumansCells
  149. Byrn RA, Mordenti J, Lucas C, Smith D, Marsters SA, Johnson JS, Cossum P, Chamow SM, Wurm FM, Gregory T, Groopman JE, Capon DJ. Biological properties of a CD4 immunoadhesin. Nature. 1990 Apr 12; 344(6267):667-70. PMID: 1970124.
    Citations: 51     Fields:    Translation:HumansAnimalsCells
  150. Molina JM, Sakaguchi M, Groopman JE. Effect of recombinant soluble CD4 on the in vitro growth of hematopoietic progenitor cells from AIDS patients. Blood. 1990 Mar 15; 75(6):1379-80. PMID: 2310836.
    Citations:    Fields:    Translation:HumansCells
  151. Groopman JE. Status of colony-stimulating factors in cancer and AIDS. Semin Oncol. 1990 Feb; 17(1 Suppl 1):31-7; discussion 38-41. PMID: 2405493.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  152. Groopman JE. Retroviral infection and haemopoiesis. Ciba Found Symp. 1990; 148:173-80; discussion 180-5. PMID: 2156659.
    Citations:    Fields:    Translation:Humans
  153. Heagy W, Groopman J, Schindler J, Finberg R. Use of IFN-gamma in patients with AIDS. J Acquir Immune Defic Syndr (1988). 1990; 3(6):584-90. PMID: 2110972.
    Citations: 10     Fields:    Translation:HumansCTClinical Trials
  154. Seage GR, Horsburgh CR, Hardy AM, Mayer KH, Barry MA, Groopman JE, Jaffe HW, Lamb GA. Increased suppressor T cells in probable transmitters of human immunodeficiency virus infection. Am J Public Health. 1989 Dec; 79(12):1638-42. PMID: 2530906.
    Citations: 1     Fields:    Translation:HumansCells
  155. Molina JM, Groopman JE. Bone marrow toxicity of dideoxyinosine. N Engl J Med. 1989 Nov 23; 321(21):1478. PMID: 2509914.
    Citations: 4     Fields:    Translation:HumansCells
  156. Groopman JE, Molina JM, Scadden DT. Hematopoietic growth factors. Biology and clinical applications. N Engl J Med. 1989 Nov 23; 321(21):1449-59. PMID: 2682244.
    Citations: 46     Fields:    Translation:Humans
  157. Byrn RA, Sekigawa I, Chamow SM, Johnson JS, Gregory TJ, Capon DJ, Groopman JE. Characterization of in vitro inhibition of human immunodeficiency virus by purified recombinant CD4. J Virol. 1989 Oct; 63(10):4370-5. PMID: 2550671.
    Citations: 20     Fields:    Translation:Cells
  158. Scadden DT, Zon LI, Groopman JE. Pathophysiology and management of HIV-associated hematologic disorders. Blood. 1989 Oct; 74(5):1455-63. PMID: 2676010.
    Citations: 26     Fields:    Translation:Humans
  159. Molina JM, Scadden DT, Byrn R, Dinarello CA, Groopman JE. Production of tumor necrosis factor alpha and interleukin 1 beta by monocytic cells infected with human immunodeficiency virus. J Clin Invest. 1989 Sep; 84(3):733-7. PMID: 2474573.
    Citations: 47     Fields:    Translation:HumansCells
  160. Berman PW, Riddle L, Nakamura G, Haffar OK, Nunes WM, Skehel P, Byrn R, Groopman J, Matthews T, Gregory T. Expression and immunogenicity of the extracellular domain of the human immunodeficiency virus type 1 envelope glycoprotein, gp160. J Virol. 1989 Aug; 63(8):3489-98. PMID: 2545918.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  161. Groopman JE. New directions in hematologic biotherapy. Semin Hematol. 1989 Jul; 26(3 Suppl 3):1-6. PMID: 2477903.
    Citations:    Fields:    Translation:Humans
  162. Gurley RJ, Ikeuchi K, Byrn RA, Anderson K, Groopman JE. CD4+ lymphocyte function with early human immunodeficiency virus infection. Proc Natl Acad Sci U S A. 1989 Mar; 86(6):1993-7. PMID: 2564677.
    Citations: 26     Fields:    Translation:HumansCells
  163. Groopman JE, Scadden DT. Interferon therapy for Kaposi sarcoma associated with the acquired immunodeficiency syndrome (AIDS) Ann Intern Med. 1989 Mar 01; 110(5):335-7. PMID: 2644884.
    Citations: 4     Fields:    Translation:Humans
  164. Ezekowitz RA, Kuhlman M, Groopman JE, Byrn RA. A human serum mannose-binding protein inhibits in vitro infection by the human immunodeficiency virus. J Exp Med. 1989 Jan 01; 169(1):185-96. PMID: 2909656.
    Citations: 84     Fields:    Translation:HumansCells
  165. Groopman JE. Clinical applications of colony-stimulating factors. Semin Oncol. 1988 Dec; 15(6 Suppl 6):27-33. PMID: 2462748.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  166. Johnson M, Caiazzo T, Molina JM, Donahue R, Groopman J. Inhibition of bone marrow myelopoiesis and erythropoiesis in vitro by anti-retroviral nucleoside derivatives. Br J Haematol. 1988 Oct; 70(2):137-41. PMID: 2847772.
    Citations: 11     Fields:    Translation:HumansCells
  167. Zon LI, Groopman JE. Hematologic manifestations of the human immune deficiency virus (HIV). Semin Hematol. 1988 Jul; 25(3):208-18. PMID: 3043675.
    Citations: 26     Fields:    Translation:HumansCells
  168. Groopman JE. Colony-stimulating factors: present status and future applications. Semin Hematol. 1988 Jul; 25(3 Suppl 3):30-7. PMID: 3051407.
    Citations: 2     Fields:    Translation:Humans
  169. Berman PW, Groopman JE, Gregory T, Clapham PR, Weiss RA, Ferriani R, Riddle L, Shimasaki C, Lucas C, Lasky LA, et al. Human immunodeficiency virus type 1 challenge of chimpanzees immunized with recombinant envelope glycoprotein gp120. Proc Natl Acad Sci U S A. 1988 Jul; 85(14):5200-4. PMID: 2455898.
    Citations: 38     Fields:    Translation:AnimalsCellsPHPublic Health
  170. Groopman JE, Caiazzo T, Thomas MA, Ferriani RA, Saltzman S, Moon M, Seage G, Horsburgh CR, Mayer K. Lack of evidence of prolonged human immunodeficiency virus infection before antibody seroconversion. Blood. 1988 Jun; 71(6):1752-4. PMID: 3370318.
    Citations: 1     Fields:    
  171. O'Hara CJ, Groopman JE, Federman M. The ultrastructural and immunohistochemical demonstration of viral particles in lymph nodes from human immunodeficiency virus-related and non-human immunodeficiency virus-related lymphadenopathy syndromes. Hum Pathol. 1988 May; 19(5):545-9. PMID: 3371979.
    Citations: 5     Fields:    Translation:HumansCells
  172. McCusker J, Stoddard AM, Mayer KH, Cowan DN, Groopman JE. Behavioral risk factors for HIV infection among homosexual men at a Boston community health center. Am J Public Health. 1988 Jan; 78(1):68-71. PMID: 3422139.
    Citations: 6     Fields:    Translation:HumansCells
  173. Smith DH, Byrn RA, Marsters SA, Gregory T, Groopman JE, Capon DJ. Blocking of HIV-1 infectivity by a soluble, secreted form of the CD4 antigen. Science. 1987 Dec 18; 238(4834):1704-7. PMID: 3500514.
    Citations: 141     Fields:    Translation:HumansAnimalsCells
  174. Benotti PN, Jenkins RL, Cady B, O'Hara C, Groopman JE. Surgical approach to generalized lymphadenopathy in homosexual men. J Surg Oncol. 1987 Dec; 36(4):231-4. PMID: 3695526.
    Citations: 1     Fields:    Translation:Humans
  175. Cheson BD, Levine AM, Mildvan D, Kaplan LD, Wolfe P, Rios A, Groopman JE, Gill P, Volberding PA, Poiesz BJ, et al. Suramin therapy in AIDS and related disorders. Report of the US Suramin Working Group. JAMA. 1987 Sep 11; 258(10):1347-51. PMID: 3650339.
    Citations: 12     Fields:    Translation:HumansCells
  176. Groopman JE, Mitsuyasu RT, DeLeo MJ, Oette DH, Golde DW. Effect of recombinant human granulocyte-macrophage colony-stimulating factor on myelopoiesis in the acquired immunodeficiency syndrome. N Engl J Med. 1987 Sep 03; 317(10):593-8. PMID: 3497344.
    Citations: 75     Fields:    Translation:Humans
  177. Mayer KH, Falk LA, Paul DA, Dawson GJ, Stoddard AM, McCusker J, Saltzman SP, Moon MW, Ferriani R, Groopman JE. Correlation of enzyme-linked immunosorbent assays for serum human immunodeficiency virus antigen and antibodies to recombinant viral proteins with subsequent clinical outcomes in a cohort of asymptomatic homosexual men. Am J Med. 1987 Aug; 83(2):208-12. PMID: 3650022.
    Citations: 9     Fields:    Translation:HumansCells
  178. Richman DD, Fischl MA, Grieco MH, Gottlieb MS, Volberding PA, Laskin OL, Leedom JM, Groopman JE, Mildvan D, Hirsch MS, et al. The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial. N Engl J Med. 1987 Jul 23; 317(4):192-7. PMID: 3299090.
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