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profileJoanne Clark, D.Phil.

TitleInstructor in Neurology
InstitutionBeth Israel Deaconess Medical Center
DepartmentNeurology
AddressCenter for Life Science
3 Blackfan Circle
Boston MA 02115
Phone617/735-2822
Fax617/667-0800
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Shurubor, Y.I.; D’Aurelio, M.; Clark-Matott, J.; Isakova, E.P.; Deryabina, Y.I.; Beal, M.F.; Cooper, A.J.L.; Krasnikov, B.F. . Determination of Coenzyme A and Acetyl-Coenzyme A in Biological Samples Using HPLC with UV Detection. Molecules. 2017; 22:1388.
  2. Clark-Matott J, Saleem A, Dai Y, Shurubor Y, Ma X, Safdar A, Beal MF, Tarnopolsky M, Simon DK. Metabolomic analysis of exercise effects in the POLG mitochondrial DNA mutator mouse brain. Neurobiol Aging. 2015 Nov; 36(11):2972-2983. PMID: 26294258; PMCID: PMC4609600 [Available on 11/01/16].
  3. Simon DK, Simuni T, Elm J, Clark-Matott J, Graebner AK, Baker L, Dunlop SR, Emborg M, Kamp C, Morgan JC, Ross GW, Sharma S, Ravina B. Peripheral Biomarkers of Parkinson's Disease Progression and Pioglitazone Effects. J Parkinsons Dis. 2015; 5(4):731-6. PMID: 26444095.
    View in: PubMed
  4. Dai Y, Clark J, Zheng K, Kujoth GC, Prolla TA, Simon DK. Somatic mitochondrial DNA mutations do not increase neuronal vulnerability to MPTP in young POLG mutator mice. Neurotoxicol Teratol. 2014 Nov-Dec; 46:62-7. PMID: 25450660; PMCID: PMC4293310.
  5. Dai Y, Zheng K, Clark J, Swerdlow RH, Pulst SM, Sutton JP, Shinobu LA, Simon DK. Rapamycin drives selection against a pathogenic heteroplasmic mitochondrial DNA mutation. Hum Mol Genet. 2014 Feb 01; 23(3):637-47. PMID: 24101601; PMCID: PMC3888257.
  6. Dai Y, Kiselak T, Clark J, Clore E, Zheng K, Cheng A, Kujoth GC, Prolla TA, Maratos-Flier E, Simon DK. Behavioral and metabolic characterization of heterozygous and homozygous POLG mutator mice. Mitochondrion. 2013 Jul; 13(4):282-91. PMID: 23542163; PMCID: PMC3682692.
  7. Clark J, Silvaggi JM, Kiselak T, Zheng K, Clore EL, Dai Y, Bass CE, Simon DK. Pgc-1a overexpression downregulates Pitx3 and increases susceptibility to MPTP toxicity associated with decreased Bdnf. PLoS One. 2012; 7(11):e48925. PMID: 23145024; PMCID: PMC3492133.
  8. Clark J, Reddy S, Zheng K, Betensky RA, Simon DK. Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease. BMC Med Genet. 2011 May 19; 12:69. PMID: 21595954; PMCID: PMC3112073.
  9. Clark J, Dai Y, Simon DK. Do somatic mitochondrial DNA mutations contribute to Parkinson's disease? Parkinsons Dis. 2011; 2011:659694. PMID: 21603185; PMCID: PMC3096076.
  10. Clark J, Clore EL, Zheng K, Adame A, Masliah E, Simon DK. Oral N-acetyl-cysteine attenuates loss of dopaminergic terminals in alpha-synuclein overexpressing mice. PLoS One. 2010 Aug 23; 5(8):e12333. PMID: 20808797; PMCID: PMC2925900.
  11. Clark J, Simon DK. Transcribe to survive: transcriptional control of antioxidant defense programs for neuroprotection in Parkinson's disease. Antioxid Redox Signal. 2009 Mar; 11(3):509-28. PMID: 18717631.
    View in: PubMed
  12. Oliver PL, Bitoun E, Clark J, Jones EL, Davies KE. Mediation of Af4 protein function in the cerebellum by Siah proteins. Proc Natl Acad Sci U S A. 2004 Oct 12; 101(41):14901-6. PMID: 15459319; PMCID: PMC522018.
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