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Last Name

profileDouglas B. Cowan, Ph.D.

TitleAssociate Professor of Anaesthesia
InstitutionBoston Children's Hospital
AddressChildren's Hospital
Anesthesiology (Enders 312.1)
300 Longwood Ave
Boston MA 02115
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Our laboratory is developing cell-based therapies to treat heart disease in humans. Currently, we are focused on the following pre-clinical research projects: 1) Engineering tissue to function as a permanent atrioventricular (AV) electrical conduit as an alternative to pacemaker implantation in children with complete heart block, 2) Designing methods to expand and direct the differentiation of stem cell populations to determine their regenerative potential for treatment of cardiac diseases, 3) Assessing non-invasive, imaging modalities to serially track the retention, distribution, and function of transplanted cells in experimental therapeutic trials, and 4) Transplanting mitochondria to the heart to decrease the extent of damage following a heart attack and enhance functional recovery.

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
12GRNT11910008     (COWAN, DOUGLAS B.)Jul 1, 2012 - Jun 30, 2016
Characterization of Cardiac Progenitor Cells from Adult Skeletal Muscle
Role: Principal Investigator

Grant's Gala, Jasper Johnson Memorial Fund     (COWAN, DOUGLAS B.)Jan 1, 2012 - Dec 31, 2015
Development of a Cell-based Therapy for Congenital Complete Heart Block
Role: Principal Investigator

R01HL088206     (COWAN, DOUGLAS B.)Jul 18, 2007 - Jun 30, 2013
Expansion and Directed Differentiation of Adult Side Population Stem Cells
Role: Principal Investigator

R01HL068915     (COWAN, DOUGLAS B.)Jan 18, 2002 - May 31, 2011
Cardiac Conduction through Engineered Tissue
Role: Principal Investigator

Child Health Research Grant     (Douglas B. Cowan)Jul 1, 2000 - Jun 30, 2002
Charles H. Hood Foundation
Endotoxin-Induced Cardiac Signal Transduction
Role: Principal Investigator

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Cowan DB, Yao R, Thedsanamoorthy JK, Zurakowski D, Del Nido PJ, McCully JD. Transit and integration of extracellular mitochondria in human heart cells. Sci Rep. 2017 Dec 12; 7(1):17450. PMID: 29234096.
    View in: PubMed
  2. McCully JD, Cowan DB, Emani SM, Del Nido PJ. Mitochondrial transplantation: From animal models to clinical use in humans. Mitochondrion. 2017 May; 34:127-134. PMID: 28342934.
    View in: PubMed
  3. Shin B, Cowan DB, Emani SM, Del Nido PJ, McCully JD. Mitochondrial Transplantation in Myocardial Ischemia and Reperfusion Injury. Adv Exp Med Biol. 2017; 982:595-619. PMID: 28551809.
    View in: PubMed
  4. Kaza AK, Wamala I, Friehs I, Kuebler JD, Rathod RH, Berra I, Ericsson M, Yao R, Thedsanamoorthy JK, Zurakowski D, Levitsky S, Del Nido PJ, Cowan DB, McCully JD. Myocardial rescue with autologous mitochondrial transplantation in a porcine model of ischemia/reperfusion. J Thorac Cardiovasc Surg. 2017 Apr; 153(4):934-943. PMID: 27938904.
    View in: PubMed
  5. Cowan DB, Yao R, Akurathi V, Snay ER, Thedsanamoorthy JK, Zurakowski D, Ericsson M, Friehs I, Wu Y, Levitsky S, Del Nido PJ, Packard AB, McCully JD. Intracoronary Delivery of Mitochondria to the Ischemic Heart for Cardioprotection. PLoS One. 2016; 11(8):e0160889. PMID: 27500955; PMCID: PMC4976938.
  6. McCully JD, Levitsky S, Del Nido PJ, Cowan DB. Mitochondrial transplantation for therapeutic use. Clin Transl Med. 2016 Mar; 5(1):16. PMID: 27130633; PMCID: PMC4851669.
  7. Neef K, Treskes P, Xu G, Drey F, Srinivasan SP, Saric T, Nembo E, Semmler J, Nguemo F, Stamm C, Cowan DB, Deppe AC, Scherner M, Wittwer T, Hescheler J, Wahlers T, Choi YH. Dynamic Support Culture of Murine Skeletal Muscle-Derived Stem Cells Improves Their Cardiogenic Potential In Vitro. Stem Cells Int. 2015; 2015:247091. PMID: 26357517; PMCID: PMC4556334.
  8. Bartholomä MD, Zhang S, Akurathi V, Pacak CA, Dunning P, Fahey FH, Cowan DB, Treves ST, Packard AB. (18)F-labeled rhodamines as potential myocardial perfusion agents: comparison of pharmacokinetic properties of several rhodamines. Nucl Med Biol. 2015 Oct; 42(10):796-803. PMID: 26205075; PMCID: PMC4567415 [Available on 10/01/16].
  9. Pacak CA, Preble JM, Kondo H, Seibel P, Levitsky S, Del Nido PJ, Cowan DB, McCully JD. Actin-dependent mitochondrial internalization in cardiomyocytes: evidence for rescue of mitochondrial function. Biol Open. 2015 Apr 10; 4(5):622-6. PMID: 25862247; PMCID: PMC4434813.
  10. Pacak CA, Hammer PE, MacKay AA, Dowd RP, Wang KR, Masuzawa A, Sill B, McCully JD, Cowan DB. Superparamagnetic iron oxide nanoparticles function as a long-term, multi-modal imaging label for non-invasive tracking of implanted progenitor cells. PLoS One. 2014; 9(9):e108695. PMID: 25250622; PMCID: PMC4177390.
  11. Treskes P, Neef K, Perumal Srinivasan S, Halbach M, Stamm C, Cowan D, Scherner M, Madershahian N, Wittwer T, Hescheler J, Wahlers T, Choi YH. Preconditioning of skeletal myoblast-based engineered tissue constructs enables functional coupling to myocardium in vivo. J Thorac Cardiovasc Surg. 2015 Jan; 149(1):348-56. PMID: 25439779; PMCID: PMC4476636.
  12. Preble JM, Pacak CA, Kondo H, MacKay AA, Cowan DB, McCully JD. Rapid isolation and purification of mitochondria for transplantation by tissue dissociation and differential filtration. J Vis Exp. 2014 Sep 06; (91):e51682. PMID: 25225817; PMCID: PMC4828055.
  13. Pacak CA, MacKay AA, Cowan DB. An improved method for the preparation of type I collagen from skin. J Vis Exp. 2014 Jan 21; (83):e51011. PMID: 24473107; PMCID: PMC4089470.
  14. Pacak CA, Cowan DB. Growth of bone marrow and skeletal muscle side population stem cells in suspension culture. Methods Mol Biol. 2014; 1210:51-61. PMID: 25173160.
    View in: PubMed
  15. Bartholomä MD, He H, Pacak CA, Dunning P, Fahey FH, McGowan FX, Cowan DB, Treves ST, Packard AB. Biological characterization of F-18-labeled rhodamine B, a potential positron emission tomography perfusion tracer. Nucl Med Biol. 2013 Nov; 40(8):1043-8. PMID: 24011396; PMCID: PMC3820364.
  16. Pacak CA, Eddy MT, Woodhull L, Wang KR, Alpatov I, Fullen S, Dowd RP, Choi YH, Cowan DB. Microcarrier-based expansion of adult murine side population stem cells. PLoS One. 2013; 8(1):e55187. PMID: 23383102; PMCID: PMC3557248.
  17. Masuzawa A, Black KM, Pacak CA, Ericsson M, Barnett RJ, Drumm C, Seth P, Bloch DB, Levitsky S, Cowan DB, McCully JD. Transplantation of autologously derived mitochondria protects the heart from ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol. 2013 Apr 01; 304(7):H966-82. PMID: 23355340; PMCID: PMC3625892.
  18. Friehs I, Cowan DB, Choi YH, Black KM, Barnett R, Bhasin MK, Daly C, Dillon SJ, Libermann TA, McGowan FX, del Nido PJ, Levitsky S, McCully JD. Pressure-overload hypertrophy of the developing heart reveals activation of divergent gene and protein pathways in the left and right ventricular myocardium. Am J Physiol Heart Circ Physiol. 2013 Mar 01; 304(5):H697-708. PMID: 23262132; PMCID: PMC3833994.
  19. Neef K, Choi YH, Srinivasan SP, Treskes P, Cowan DB, Stamm C, Rubach M, Adelmann R, Wittwer T, Wahlers T. Mechanical preconditioning enables electrophysiologic coupling of skeletal myoblast cells to myocardium. J Thorac Cardiovasc Surg. 2012 Nov; 144(5):1176-1184.e1. PMID: 22980065; PMCID: PMC4334564.
  20. Srinivasan SP, Neef K, Treskes P, Liakopoulos OJ, Stamm C, Cowan DB, Madershahian N, Kuhn E, Slottosch I, Wittwer T, Wahlers T, Choi YH. Enhanced gap junction expression in myoblast-containing engineered tissue. Biochem Biophys Res Commun. 2012 Jun 08; 422(3):462-468. PMID: 22579687; PMCID: PMC4346167.
  21. Pacak CA, Powers JM, Cowan DB. Ultrarapid purification of collagen type I for tissue engineering applications. Tissue Eng Part C Methods. 2011 Sep; 17(9):879-85. PMID: 21486201; PMCID: PMC3162468.
  22. Sill B, Roy N, Hammer PE, Triedman JK, Sigg DC, Kelly MF, Nedder A, Dunning PS, Cowan DB. Development of an ovine model of pediatric complete heart block. J Surg Res. 2011 Apr; 166(2):e103-8. PMID: 21227467; PMCID: PMC3073560.
  23. Wolf CM, Seslar SP, den Boer K, Juraszek AL, McGowan FX, Cowan DB, Del Nido P, Triedman JK, Berul CI, Walsh EP. Atrial remodeling after the Fontan operation. Am J Cardiol. 2009 Dec 15; 104(12):1737-42. PMID: 19962486; PMCID: PMC3399422.
  24. Kitahori K, He H, Kawata M, Cowan DB, Friehs I, Del Nido PJ, McGowan FX. Development of left ventricular diastolic dysfunction with preservation of ejection fraction during progression of infant right ventricular hypertrophy. Circ Heart Fail. 2009 Nov; 2(6):599-607. PMID: 19919985; PMCID: PMC4235516.
  25. Sill B, Hammer PE, Cowan DB. Optical mapping of Langendorff-perfused rat hearts. J Vis Exp. 2009 Aug 11; (30). PMID: 19684567; PMCID: PMC3142858.
  26. Toumpoulis IK, Oxford JT, Cowan DB, Anagnostopoulos CE, Rokkas CK, Chamogeorgakis TP, Angouras DC, Shemin RJ, Navab M, Ericsson M, Federman M, Levitsky S, McCully JD. Differential expression of collagen type V and XI alpha-1 in human ascending thoracic aortic aneurysms. Ann Thorac Surg. 2009 Aug; 88(2):506-13. PMID: 19632402; PMCID: PMC2834780.
  27. Choi YH, Cowan DB, Wahlers TC, Hetzer R, Del Nido PJ, Stamm C. Calcium sensitisation impairs diastolic relaxation in post-ischaemic myocardium: implications for the use of Ca(2+) sensitising inotropes after cardiac surgery. Eur J Cardiothorac Surg. 2010 Feb; 37(2):376-83. PMID: 19616444; PMCID: PMC4335314.
  28. Sill B, Alpatov IV, Pacak CA, Cowan DB. Implantation of engineered tissue in the rat heart. J Vis Exp. 2009 Jun 24; (28). PMID: 19553905; PMCID: PMC3253650.
  29. McCully JD, Bhasin MK, Daly C, Guerrero MC, Dillon S, Liberman TA, Cowan DB, Mably JD, McGowan FX, Levitsky S. Transcriptomic and proteomic analysis of global ischemia and cardioprotection in the rabbit heart. Physiol Genomics. 2009 Jul 09; 38(2):125-37. PMID: 19454556; PMCID: PMC2712218.
  30. Pacak CA, Cowan DB. Fabrication of myogenic engineered tissue constructs. J Vis Exp. 2009 May 01; (27). PMID: 19412158; PMCID: PMC2794293.
  31. Choi YH, Cowan DB, Moran AM, Colan SD, Stamm C, Takeuchi K, Friehs I, del Nido PJ, McGowan FX. Myocyte apoptosis occurs early during the development of pressure-overload hypertrophy in infant myocardium. J Thorac Cardiovasc Surg. 2009 Jun; 137(6):1356-62, 1362.e1-3. PMID: 19464448; PMCID: PMC2758562.
  32. Choi YH, Cowan DB, Nathan M, Poutias D, Stamm C, del Nido PJ, McGowan FX. Myocardial hypertrophy overrides the angiogenic response to hypoxia. PLoS One. 2008; 3(12):e4042. PMID: 19112498; PMCID: PMC2603310.
  33. McCully JD, Cowan DB, Pacak CA, Toumpoulis IK, Dayalan H, Levitsky S. Injection of isolated mitochondria during early reperfusion for cardioprotection. Am J Physiol Heart Circ Physiol. 2009 Jan; 296(1):H94-H105. PMID: 18978192; PMCID: PMC2637784.
  34. Roy N, Friehs I, Cowan DB, Zurakowski D, McGowan FX, del Nido PJ. Dopamine induces postischemic cardiomyocyte apoptosis in vivo: an effect ameliorated by propofol. Ann Thorac Surg. 2006 Dec; 82(6):2192-9. PMID: 17126134.
    View in: PubMed
  35. Yoon S, Molloy MJ, Wu MP, Cowan DB, Gussoni E. C6ORF32 is upregulated during muscle cell differentiation and induces the formation of cellular filopodia. Dev Biol. 2007 Jan 01; 301(1):70-81. PMID: 17150207; PMCID: PMC1779902.
  36. Tansey EE, Kwaku KF, Hammer PE, Cowan DB, Federman M, Levitsky S, McCully JD. Reduction and redistribution of gap and adherens junction proteins after ischemia and reperfusion. Ann Thorac Surg. 2006 Oct; 82(4):1472-9. PMID: 16996956; PMCID: PMC1805692.
  37. Cowan DB, McGowan FX. A paradigm shift in cardiac pacing therapy? Circulation. 2006 Sep 05; 114(10):986-8. PMID: 16952993; PMCID: PMC1570537.
  38. Choi YH, Stamm C, Hammer PE, Kwaku KF, Marler JJ, Friehs I, Jones M, Rader CM, Roy N, Eddy MT, Triedman JK, Walsh EP, McGowan FX, del Nido PJ, Cowan DB. Cardiac conduction through engineered tissue. Am J Pathol. 2006 Jul; 169(1):72-85. PMID: 16816362; PMCID: PMC1534117.
  39. Luxameechanporn T, Hadlock T, Shyu J, Cowan D, Faquin W, Varvares M. Successful myoblast transplantation in rat tongue reconstruction. Head Neck. 2006 Jun; 28(6):517-24. PMID: 16619280.
    View in: PubMed
  40. Bayliss PE, Bellavance KL, Whitehead GG, Abrams JM, Aegerter S, Robbins HS, Cowan DB, Keating MT, O'Reilly T, Wood JM, Roberts TM, Chan J. Chemical modulation of receptor signaling inhibits regenerative angiogenesis in adult zebrafish. Nat Chem Biol. 2006 May; 2(5):265-73. PMID: 16565716; PMCID: PMC1534118.
  41. Chen JN, Cowan DB, Mably JD. Cardiogenesis and the regulation of cardiac-specific gene expression. Heart Fail Clin. 2005 Jul; 1(2):157-70. PMID: 17386843.
    View in: PubMed
  42. Nathan M, Friehs I, Choi YH, Cowan DB, Cao-Danh H, McGowan FX, del Nido PJ. Cyclosporin A but not FK-506 protects against dopamine-induced apoptosis in the stunned heart. Ann Thorac Surg. 2005 May; 79(5):1620-6. PMID: 15854943.
    View in: PubMed
  43. Friehs I, Moran AM, Stamm C, Choi YH, Cowan DB, McGowan FX, del Nido PJ. Promoting angiogenesis protects severely hypertrophied hearts from ischemic injury. Ann Thorac Surg. 2004 Jun; 77(6):2004-10; discussion 2011. PMID: 15172254.
    View in: PubMed
  44. Stamm C, Cowan DB. Endotoxemia and cardiac function. J Thorac Cardiovasc Surg. 2004 Jan; 127(1):305. PMID: 14752463.
    View in: PubMed
  45. Bunaprasert T, Hadlock T, Marler J, Kobler J, Cowan D, Faquin W, Varvares M. Tissue engineered muscle implantation for tongue reconstruction: a preliminary report. Laryngoscope. 2003 Oct; 113(10):1792-7. PMID: 14520108.
    View in: PubMed
  46. Cowan DB, Jones M, Garcia LM, Noria S, del Nido PJ, McGowan FX. Hypoxia and stretch regulate intercellular communication in vascular smooth muscle cells through reactive oxygen species formation. Arterioscler Thromb Vasc Biol. 2003 Oct 01; 23(10):1754-60. PMID: 12958040.
    View in: PubMed
  47. Friehs I, Cao-Danh H, Stamm C, Cowan DB, McGowan FX, del Nido PJ. Postnatal increase in insulin-sensitive glucose transporter expression is associated with improved recovery of postischemic myocardial function. J Thorac Cardiovasc Surg. 2003 Jul; 126(1):263-71. PMID: 12878964.
    View in: PubMed
  48. McCully JD, Wakiyama H, Cowan DB, Federman M, Parker RA, Levitsky S. Diazoxide amelioration of myocardial injury and mitochondrial damage during cardiac surgery. Ann Thorac Surg. 2002 Dec; 74(6):2138-45; discussion 2146. PMID: 12643408; PMCID: PMC3668433.
  49. Stamm C, Friehs I, Cowan DB, Cao-Danh H, Choi YH, Duebener LF, McGowan FX, del Nido PJ. Dopamine treatment of postischemic contractile dysfunction rapidly induces calcium-dependent pro-apoptotic signaling. Circulation. 2002 Sep 24; 106(12 Suppl 1):I290-8. PMID: 12354748.
    View in: PubMed
  50. Chanani NK, Cowan DB, Takeuchi K, Poutias DN, Garcia LM, del Nido PJ, McGowan FX. Differential effects of amrinone and milrinone upon myocardial inflammatory signaling. Circulation. 2002 Sep 24; 106(12 Suppl 1):I284-9. PMID: 12354747.
    View in: PubMed
  51. Munakata M, Stamm C, Friehs I, Zurakowski D, Cowan DB, Cao-Danh H, McGowan FX, del Nido PJ. Protective effects of protein kinase C during myocardial ischemia require activation of phosphatidyl-inositol specific phospholipase C. Ann Thorac Surg. 2002 Apr; 73(4):1236-45. PMID: 11998814.
    View in: PubMed
  52. Wakiyama H, Cowan DB, Toyoda Y, Federman M, Levitsky S, McCully JD. Selective opening of mitochondrial ATP-sensitive potassium channels during surgically induced myocardial ischemia decreases necrosis and apoptosis. Eur J Cardiothorac Surg. 2002 Mar; 21(3):424-33. PMID: 11888758; PMCID: PMC3711118.
  53. Soriano SG, Cowan DB, Proctor MR, Scott RM. Levels of soluble adhesion molecules are elevated in the cerebrospinal fluid of children with moyamoya syndrome. Neurosurgery. 2002 Mar; 50(3):544-9. PMID: 11841722.
    View in: PubMed
  54. Merante F, Altamentova SM, Mickle DA, Weisel RD, Thatcher BJ, Martin BM, Marshall JG, Tumiati LC, Cowan DB, Li RK. The characterization and purification of a human transcription factor modulating the glutathione peroxidase gene in response to oxygen tension. Mol Cell Biochem. 2002 Jan; 229(1-2):73-83. PMID: 11936849.
    View in: PubMed
  55. Stamm C, Cowan DB, Friehs I, Noria S, del Nido PJ, McGowan FX. Rapid endotoxin-induced alterations in myocardial calcium handling: obligatory role of cardiac TNF-alpha. Anesthesiology. 2001 Dec; 95(6):1396-405. PMID: 11748398.
    View in: PubMed
  56. Stamm C, Friehs I, Cowan DB, Moran AM, Cao-Danh H, Duebener LF, del Nido PJ, McGowan FX. Inhibition of tumor necrosis factor-alpha improves postischemic recovery of hypertrophied hearts. Circulation. 2001 Sep 18; 104(12 Suppl 1):I350-5. PMID: 11568081.
    View in: PubMed
  57. Stamm C, Friehs I, Cowan DB, Cao-Danh H, Noria S, Munakata M, McGowan FX, del Nido PJ. Post-ischemic PKC inhibition impairs myocardial calcium handling and increases contractile protein calcium sensitivity. Cardiovasc Res. 2001 Jul; 51(1):108-21. PMID: 11399253.
    View in: PubMed
  58. Cowan DB, Noria S, Stamm C, Garcia LM, Poutias DN, del Nido PJ, McGowan FX. Lipopolysaccharide internalization activates endotoxin-dependent signal transduction in cardiomyocytes. Circ Res. 2001 Mar 16; 88(5):491-8. PMID: 11249872.
    View in: PubMed
  59. MacGowan GA, Du C, Cowan DB, Stamm C, McGowan FX, Solaro RJ, Koretsky AP, Del Nido PJ. Ischemic dysfunction in transgenic mice expressing troponin I lacking protein kinase C phosphorylation sites. Am J Physiol Heart Circ Physiol. 2001 Feb; 280(2):H835-43. PMID: 11158984.
    View in: PubMed
  60. Takeuchi K, del Nido PJ, Poutias DN, Cowan DB, Munakata M, McGowan FX. Vesnarinone restores contractility and calcium handling in early endotoxemia. Circulation. 2000 Nov 07; 102(19 Suppl 3):III365-9. PMID: 11082415.
    View in: PubMed
  61. Cowan DB, Poutias DN, Del Nido PJ, McGowan FX. CD14-independent activation of cardiomyocyte signal transduction by bacterial endotoxin. Am J Physiol Heart Circ Physiol. 2000 Aug; 279(2):H619-29. PMID: 10924061.
    View in: PubMed
  62. Noria S, Cowan DB, Gotlieb AI, Langille BL. Transient and steady-state effects of shear stress on endothelial cell adherens junctions. Circ Res. 1999 Sep 17; 85(6):504-14. PMID: 10488053.
    View in: PubMed
  63. Takeuchi K, del Nido PJ, Ibrahim AE, Poutias DN, Glynn P, Cao-Danh H, Cowan DB, McGowan FX. Increased myocardial calcium cycling and reduced myofilament calcium sensitivity in early endotoxemia. Surgery. 1999 Aug; 126(2):231-8. PMID: 10455889.
    View in: PubMed
  64. Takeuchi K, del Nido PJ, Ibrahim AE, Cao-Danh H, Friehs I, Glynn P, Poutias D, Cowan DB, McGowan FX. Vesnarinone and amrinone reduce the systemic inflammatory response syndrome. J Thorac Cardiovasc Surg. 1999 Feb; 117(2):375-82. PMID: 9918980.
    View in: PubMed
  65. Cowan DB, Lye SJ, Langille BL. Regulation of vascular connexin43 gene expression by mechanical loads. Circ Res. 1998 Apr 20; 82(7):786-93. PMID: 9562438.
    View in: PubMed
  66. Cowan DB, Langille BL. Cellular and molecular biology of vascular remodeling. Curr Opin Lipidol. 1996 Apr; 7(2):94-100. PMID: 8743902.
    View in: PubMed
  67. Li RK, Cowan DB, Mickle DA, Weisel RD, Burton GW. Effect of vitamin E on human glutathione peroxidase (GSH-PX1) expression in cardiomyocytes. Free Radic Biol Med. 1996; 21(4):419-26. PMID: 8886791.
    View in: PubMed
  68. Cowan DB, Weisel RD, Williams WG, Mickle DA. Identification of oxygen responsive elements in the 5'-flanking region of the human glutathione peroxidase gene. J Biol Chem. 1993 Dec 25; 268(36):26904-10. PMID: 8262924.
    View in: PubMed
  69. Cowan DB, Weisel RD, Williams WG, Mickle DA. The regulation of glutathione peroxidase gene expression by oxygen tension in cultured human cardiomyocytes. J Mol Cell Cardiol. 1992 Apr; 24(4):423-33. PMID: 1535667.
    View in: PubMed
  70. Cowan DB, Chaban G, Liew CC. The DNA-binding properties of a rat nuclear phosphoprotein. Biochem J. 1991 Mar 15; 274 ( Pt 3):687-91. PMID: 2012598; PMCID: PMC1149966.
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