Douglas B. Cowan, Ph.D.
|Title||Associate Professor of Anaesthesia|
|Institution||Children's Hospital Boston|
Anesthesiology (Enders 312.1)
300 Longwood Ave
Boston MA 02115
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Our laboratory is developing cell-based therapies to treat heart disease in humans. Currently, we are focused on the following pre-clinical research projects: 1) Engineering tissue to function as a permanent atrioventricular (AV) electrical conduit as an alternative to pacemaker implantation in children with complete heart block, 2) Designing methods to expand and direct the differentiation of stem cell populations to determine their regenerative potential for treatment of cardiac diseases, 3) Assessing non-invasive, imaging modalities to serially track the retention, distribution, and function of transplanted cells in experimental therapeutic trials, and 4) Transplanting mitochondria to the heart to decrease the extent of damage following a heart attack and enhance functional recovery.
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