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Keywords
Last Name
Institution

Mehmet Toner, PH.D.

TitleHelen Andrus Benedict Professor of Surgery
InstitutionMassachusetts General Hospital
DepartmentSurgery
AddressMassachusetts General Hospital
Center for Engineering in Medicine, Room 1401
114 16th Street
Charlestown MA 02129
Phone617/724-5336
Fax617/724-2999
vCardDownload vCard (login for email)
Other Positions
TitleProfessor of Health Sciences and Technology
InstitutionMassachusetts Institute of Technology
DepartmentHealth Sciences and Technology


 Mentoring 
 completed student projects
Development of a Microfluidic Device for Diagnosing Multidrug-Resistant Tuberculosis
Summer, 05/20/09 - 08/28/09

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Shen K, Luk S, Hicks DF, Elman JS, Bohr S, Iwamoto Y, Murray R, Pena K, Wang F, Seker E, Weissleder R, Yarmush ML, Toner M, Sgroi D, Parekkadan B. Resolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays. Nat Commun. 2014; 5:5662.
    View in: PubMed
  2. Abazari A, Chakraborty N, Hand S, Aksan A, Toner M. A Raman microspectroscopy study of water and trehalose in spin-dried cells. Biophys J. 2014 Nov 18; 107(10):2253-62.
    View in: PubMed
  3. Bersani F, Lee J, Yu M, Morris R, Desai R, Ramaswamy S, Toner M, Haber DA, Parekkadan B. Bioengineered implantable scaffolds as a tool to study stromal-derived factors in metastatic cancer models. Cancer Res. 2014 Dec 15; 74(24):7229-38.
    View in: PubMed
  4. Ting DT, Wittner BS, Ligorio M, Vincent Jordan N, Shah AM, Miyamoto DT, Aceto N, Bersani F, Brannigan BW, Xega K, Ciciliano JC, Zhu H, MacKenzie OC, Trautwein J, Arora KS, Shahid M, Ellis HL, Qu N, Bardeesy N, Rivera MN, Deshpande V, Ferrone CR, Kapur R, Ramaswamy S, Shioda T, Toner M, Maheswaran S, Haber DA. Single-cell RNA sequencing identifies extracellular matrix gene expression by pancreatic circulating tumor cells. Cell Rep. 2014 Sep 25; 8(6):1905-18.
    View in: PubMed
  5. Aceto N, Bardia A, Miyamoto DT, Donaldson MC, Wittner BS, Spencer JA, Yu M, Pely A, Engstrom A, Zhu H, Brannigan BW, Kapur R, Stott SL, Shioda T, Ramaswamy S, Ting DT, Lin CP, Toner M, Haber DA, Maheswaran S. Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis. Cell. 2014 Aug 28; 158(5):1110-22.
    View in: PubMed
  6. Sullivan JP, Nahed BV, Madden MW, Oliveira SM, Springer S, Bhere D, Chi AS, Wakimoto H, Rothenberg SM, Sequist LV, Kapur R, Shah K, Iafrate AJ, Curry WT, Loeffler JS, Batchelor TT, Louis DN, Toner M, Maheswaran S, Haber DA. Brain tumor cells in circulation are enriched for mesenchymal gene expression. Cancer Discov. 2014 Nov; 4(11):1299-309.
    View in: PubMed
  7. Wong IY, Javaid S, Wong EA, Perk S, Haber DA, Toner M, Irimia D. Collective and individual migration following the epithelial-mesenchymal transition. Nat Mater. 2014 Nov; 13(11):1063-71.
    View in: PubMed
  8. Nahed BV, Sullivan JP, Madden MW, Oliveira SM, Chi AS, Springer S, Wakimoto H, Bhere D, Shah A, Spuhler P, Batchelor T, Louis DN, Toner M, Maheswaran S, Haber DA. American brain tumor association young investigator award 198 circulating tumor cells in patients with glioblastoma. Neurosurgery. 2014 Aug; 61 Suppl 1:226.
    View in: PubMed
  9. Yu M, Bardia A, Aceto N, Bersani F, Madden MW, Donaldson MC, Desai R, Zhu H, Comaills V, Zheng Z, Wittner BS, Stojanov P, Brachtel E, Sgroi D, Kapur R, Shioda T, Ting DT, Ramaswamy S, Getz G, Iafrate AJ, Benes C, Toner M, Maheswaran S, Haber DA. Cancer therapy. Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility. Science. 2014 Jul 11; 345(6193):216-20.
    View in: PubMed
  10. Berendsen TA, Bruinsma BG, Puts CF, Saeidi N, Usta OB, Uygun BE, Izamis ML, Toner M, Yarmush ML, Uygun K. Supercooling enables long-term transplantation survival following 4 days of liver preservation. Nat Med. 2014 Jul; 20(7):790-3.
    View in: PubMed
  11. Lim EJ, Ober TJ, Edd JF, Desai SP, Neal D, Bong KW, Doyle PS, McKinley GH, Toner M. Inertio-elastic focusing of bioparticles in microchannels at high throughput. Nat Commun. 2014; 5:4120.
    View in: PubMed
  12. Liu J, Lee GY, Lawitts JA, Toner M, Biggers JD. Live Pups from Evaporatively Dried Mouse Sperm Stored at Ambient Temperature for up to 2 Years. PLoS One. 2014; 9(6):e99809.
    View in: PubMed
  13. Martel JM, Toner M. Inertial focusing in microfluidics. Annu Rev Biomed Eng. 2014 Jul 11; 16:371-96.
    View in: PubMed
  14. Luo X, Mitra D, Sullivan RJ, Wittner BS, Kimura AM, Pan S, Hoang MP, Brannigan BW, Lawrence DP, Flaherty KT, Sequist LV, McMahon M, Bosenberg MW, Stott SL, Ting DT, Ramaswamy S, Toner M, Fisher DE, Maheswaran S, Haber DA. Isolation and molecular characterization of circulating melanoma cells. Cell Rep. 2014 May 8; 7(3):645-53.
    View in: PubMed
  15. Karabacak NM, Spuhler PS, Fachin F, Lim EJ, Pai V, Ozkumur E, Martel JM, Kojic N, Smith K, Chen PI, Yang J, Hwang H, Morgan B, Trautwein J, Barber TA, Stott SL, Maheswaran S, Kapur R, Haber DA, Toner M. Microfluidic, marker-free isolation of circulating tumor cells from blood samples. Nat Protoc. 2014 Mar; 9(3):694-710.
    View in: PubMed
  16. Wong IY, Bhatia SN, Toner M. Nanotechnology: emerging tools for biology and medicine. Genes Dev. 2013 Nov 15; 27(22):2397-408.
    View in: PubMed
  17. Mittal S, Wong IY, Yanik AA, Deen WM, Toner M. Discontinuous nanoporous membranes reduce non-specific fouling for immunoaffinity cell capture. Small. 2013 Dec 20; 9(24):4207-14.
    View in: PubMed
  18. Mantel PY, Hoang AN, Goldowitz I, Potashnikova D, Hamza B, Vorobjev I, Ghiran I, Toner M, Irimia D, Ivanov AR, Barteneva N, Marti M. Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system. Cell Host Microbe. 2013 May 15; 13(5):521-34.
    View in: PubMed
  19. Desai SP, Bhatia SN, Toner M, Irimia D. Mitochondrial localization and the persistent migration of epithelial cancer cells. Biophys J. 2013 May 7; 104(9):2077-88.
    View in: PubMed
  20. Ozkumur E, Shah AM, Ciciliano JC, Emmink BL, Miyamoto DT, Brachtel E, Yu M, Chen PI, Morgan B, Trautwein J, Kimura A, Sengupta S, Stott SL, Karabacak NM, Barber TA, Walsh JR, Smith K, Spuhler PS, Sullivan JP, Lee RJ, Ting DT, Luo X, Shaw AT, Bardia A, Sequist LV, Louis DN, Maheswaran S, Kapur R, Haber DA, Toner M. Inertial focusing for tumor antigen-dependent and -independent sorting of rare circulating tumor cells. Sci Transl Med. 2013 Apr 3; 5(179):179ra47.
    View in: PubMed
  21. Yu M, Bardia A, Wittner BS, Stott SL, Smas ME, Ting DT, Isakoff SJ, Ciciliano JC, Wells MN, Shah AM, Concannon KF, Donaldson MC, Sequist LV, Brachtel E, Sgroi D, Baselga J, Ramaswamy S, Toner M, Haber DA, Maheswaran S. Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition. Science. 2013 Feb 1; 339(6119):580-4.
    View in: PubMed
  22. Liong M, Hoang AN, Chung J, Gural N, Ford CB, Min C, Shah RR, Ahmad R, Fernandez-Suarez M, Fortune SM, Toner M, Lee H, Weissleder R. Magnetic barcode assay for genetic detection of pathogens. Nat Commun. 2013; 4:1752.
    View in: PubMed
  23. Li S, Chakraborty N, Borcar A, Menze MA, Toner M, Hand SC. Late embryogenesis abundant proteins protect human hepatoma cells during acute desiccation. Proc Natl Acad Sci U S A. 2012 Dec 18; 109(51):20859-64.
    View in: PubMed
  24. Borcar A, Menze MA, Toner M, Hand SC. Metabolic preconditioning of mammalian cells: mimetic agents for hypoxia lack fidelity in promoting phosphorylation of pyruvate dehydrogenase. Cell Tissue Res. 2013 Jan; 351(1):99-106.
    View in: PubMed
  25. Miyamoto DT, Lee RJ, Stott SL, Ting DT, Wittner BS, Ulman M, Smas ME, Lord JB, Brannigan BW, Trautwein J, Bander NH, Wu CL, Sequist LV, Smith MR, Ramaswamy S, Toner M, Maheswaran S, Haber DA. Androgen receptor signaling in circulating tumor cells as a marker of hormonally responsive prostate cancer. Cancer Discov. 2012 Nov; 2(11):995-1003.
    View in: PubMed
  26. El-Haibi CP, Bell GW, Zhang J, Collmann AY, Wood D, Scherber CM, Csizmadia E, Mariani O, Zhu C, Campagne A, Toner M, Bhatia SN, Irimia D, Vincent-Salomon A, Karnoub AE. Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):17460-5.
    View in: PubMed
  27. Lechene CP, Lee GY, Poczatek JC, Toner M, Biggers JD. 3D multi-isotope imaging mass spectrometry reveals penetration of 18O-trehalose in mouse sperm nucleus. PLoS One. 2012; 7(8):e42267.
    View in: PubMed
  28. Yu M, Ting DT, Stott SL, Wittner BS, Ozsolak F, Paul S, Ciciliano JC, Smas ME, Winokur D, Gilman AJ, Ulman MJ, Xega K, Contino G, Alagesan B, Brannigan BW, Milos PM, Ryan DP, Sequist LV, Bardeesy N, Ramaswamy S, Toner M, Maheswaran S, Haber DA. RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis. Nature. 2012 Jul 26; 487(7408):510-3.
    View in: PubMed
  29. Chen GD, Fachin F, Colombini E, Wardle BL, Toner M. Nanoporous micro-element arrays for particle interception in microfluidic cell separation. Lab Chip. 2012 Sep 7; 12(17):3159-67.
    View in: PubMed
  30. Shah AM, Yu M, Nakamura Z, Ciciliano J, Ulman M, Kotz K, Stott SL, Maheswaran S, Haber DA, Toner M. Biopolymer system for cell recovery from microfluidic cell capture devices. Anal Chem. 2012 Apr 17; 84(8):3682-8.
    View in: PubMed
  31. Lim EJ, Ober TJ, Edd JF, McKinley GH, Toner M. Visualization of microscale particle focusing in diluted and whole blood using particle trajectory analysis. Lab Chip. 2012 Jun 21; 12(12):2199-210.
    View in: PubMed
  32. Mittal S, Wong IY, Deen WM, Toner M. Antibody-functionalized fluid-permeable surfaces for rolling cell capture at high flow rates. Biophys J. 2012 Feb 22; 102(4):721-30.
    View in: PubMed
  33. Scherber C, Aranyosi AJ, Kulemann B, Thayer SP, Toner M, Iliopoulos O, Irimia D. Epithelial cell guidance by self-generated EGF gradients. Integr Biol (Camb). 2012 Mar; 4(3):259-69.
    View in: PubMed
  34. Li MW, Baridon B, Trainor A, Djan E, Koehne A, Griffey SM, Biggers JD, Toner M, Lloyd KC. Mutant mice derived by ICSI of evaporatively dried spermatozoa exhibit expected phenotype. Reproduction. 2012 Apr; 143(4):449-53.
    View in: PubMed
  35. Liu J, Lee GY, Lawitts JA, Toner M, Biggers JD. Preservation of mouse sperm by convective drying and storing in 3-O-methyl-D-glucose. PLoS One. 2012; 7(1):e29924.
    View in: PubMed
  36. Hipp J, Monaco J, Kunju LP, Cheng J, Yagi Y, Rodriguez-Canales J, Emmert-Buck MR, Hewitt S, Feldman MD, Tomaszewski JE, Toner M, Tompkins RG, Flotte T, Lucas D, Gilbertson JR, Madabhushi A, Balis U. Integration of architectural and cytologic driven image algorithms for prostate adenocarcinoma identification. Anal Cell Pathol (Amst). 2012; 35(4):251-65.
    View in: PubMed
  37. Aldridge BB, Fernandez-Suarez M, Heller D, Ambravaneswaran V, Irimia D, Toner M, Fortune SM. Asymmetry and aging of mycobacterial cells lead to variable growth and antibiotic susceptibility. Science. 2012 Jan 6; 335(6064):100-4.
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  38. Chakraborty N, Menze MA, Elmoazzen H, Vu H, Yarmush ML, Hand SC, Toner M. Trehalose transporter from African chironomid larvae improves desiccation tolerance of Chinese hamster ovary cells. Cryobiology. 2012 Apr; 64(2):91-6.
    View in: PubMed
  39. Liong M, Fernandez-Suarez M, Issadore D, Min C, Tassa C, Reiner T, Fortune SM, Toner M, Lee H, Weissleder R. Specific pathogen detection using bioorthogonal chemistry and diagnostic magnetic resonance. Bioconjug Chem. 2011 Dec 21; 22(12):2390-4.
    View in: PubMed
  40. Watkins N, Irimia D, Toner M, Bashir R. On a chip. IEEE Pulse. 2011 Nov; 2(6):19-27.
    View in: PubMed
  41. Chakraborty N, Menze MA, Malsam J, Aksan A, Hand SC, Toner M. Cryopreservation of spin-dried mammalian cells. PLoS One. 2011; 6(9):e24916.
    View in: PubMed
  42. Warner EA, Kotz KT, Ungaro RF, Abouhamze AS, Lopez MC, Cuenca AG, Kelly-Scumpia KM, Moreno C, O'Malley KA, Lanz JD, Baker HV, Martin LC, Toner M, Tompkins RG, Efron PA, Moldawer LL. Microfluidics-based capture of human neutrophils for expression analysis in blood and bronchoalveolar lavage. Lab Invest. 2011 Dec; 91(12):1787-95.
    View in: PubMed
  43. Heo YS, Lee HJ, Hassell BA, Irimia D, Toth TL, Elmoazzen H, Toner M. Controlled loading of cryoprotectants (CPAs) to oocyte with linear and complex CPA profiles on a microfluidic platform. Lab Chip. 2011 Oct 21; 11(20):3530-7.
    View in: PubMed
  44. Hipp J, Flotte T, Monaco J, Cheng J, Madabhushi A, Yagi Y, Rodriguez-Canales J, Emmert-Buck M, Dugan MC, Hewitt S, Toner M, Tompkins RG, Lucas D, Gilbertson JR, Balis UJ. Computer aided diagnostic tools aim to empower rather than replace pathologists: Lessons learned from computational chess. J Pathol Inform. 2011; 2:25.
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  45. Kenar H, Kose GT, Toner M, Kaplan DL, Hasirci V. A 3D aligned microfibrous myocardial tissue construct cultured under transient perfusion. Biomaterials. 2011 Aug; 32(23):5320-9.
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  46. Chen GD, Fachin F, Fernandez-Suarez M, Wardle BL, Toner M. Nanoporous elements in microfluidics for multiscale manipulation of bioparticles. Small. 2011 Apr 18; 7(8):1061-7.
    View in: PubMed
  47. Hipp JD, Cheng JY, Toner M, Tompkins RG, Balis UJ. Spatially Invariant Vector Quantization: A pattern matching algorithm for multiple classes of image subject matter including pathology. J Pathol Inform. 2011; 2:13.
    View in: PubMed
  48. Hand SC, Menze MA, Borcar A, Patil Y, Covi JA, Reynolds JA, Toner M. Metabolic restructuring during energy-limited states: insights from Artemia franciscana embryos and other animals. J Insect Physiol. 2011 May; 57(5):584-94.
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  49. Yu M, Stott S, Toner M, Maheswaran S, Haber DA. Circulating tumor cells: approaches to isolation and characterization. J Cell Biol. 2011 Feb 7; 192(3):373-82.
    View in: PubMed
  50. Chakraborty N, Chang A, Elmoazzen H, Menze MA, Hand SC, Toner M. A spin-drying technique for lyopreservation of mammalian cells. Ann Biomed Eng. 2011 May; 39(5):1582-91.
    View in: PubMed
  51. Watkins NN, Sridhar S, Cheng X, Chen GD, Toner M, Rodriguez W, Bashir R. A microfabricated electrical differential counter for the selective enumeration of CD4+ T lymphocytes. Lab Chip. 2011 Apr 21; 11(8):1437-47.
    View in: PubMed
  52. Hand SC, Menze MA, Toner M, Boswell L, Moore D. LEA proteins during water stress: not just for plants anymore. Annu Rev Physiol. 2011; 73:115-34.
    View in: PubMed
  53. Kane BJ, Younan G, Helm D, Dastouri P, Prentice-Mott H, Irimia D, Chan RK, Toner M, Orgill DP. Controlled induction of distributed microdeformation in wounded tissue via a microchamber array dressing. J Biomed Mater Res A. 2010 Nov; 95(2):333-40.
    View in: PubMed
  54. Stott SL, Hsu CH, Tsukrov DI, Yu M, Miyamoto DT, Waltman BA, Rothenberg SM, Shah AM, Smas ME, Korir GK, Floyd FP, Gilman AJ, Lord JB, Winokur D, Springer S, Irimia D, Nagrath S, Sequist LV, Lee RJ, Isselbacher KJ, Maheswaran S, Haber DA, Toner M. Isolation of circulating tumor cells using a microvortex-generating herringbone-chip. Proc Natl Acad Sci U S A. 2010 Oct 26; 107(43):18392-7.
    View in: PubMed
  55. Kotz KT, Xiao W, Miller-Graziano C, Qian WJ, Russom A, Warner EA, Moldawer LL, De A, Bankey PE, Petritis BO, Camp DG, Rosenbach AE, Goverman J, Fagan SP, Brownstein BH, Irimia D, Xu W, Wilhelmy J, Mindrinos MN, Smith RD, Davis RW, Tompkins RG, Toner M. Clinical microfluidics for neutrophil genomics and proteomics. Nat Med. 2010 Sep; 16(9):1042-7.
    View in: PubMed
  56. Ambravaneswaran V, Wong IY, Aranyosi AJ, Toner M, Irimia D. Directional decisions during neutrophil chemotaxis inside bifurcating channels. Integr Biol (Camb). 2010 Nov; 2(11-12):639-47.
    View in: PubMed
  57. Butler KL, Ambravaneswaran V, Agrawal N, Bilodeau M, Toner M, Tompkins RG, Fagan S, Irimia D. Burn injury reduces neutrophil directional migration speed in microfluidic devices. PLoS One. 2010; 5(7):e11921.
    View in: PubMed
  58. Menze MA, Chakraborty N, Clavenna M, Banerjee M, Liu XH, Toner M, Hand SC. Metabolic preconditioning of cells with AICAR-riboside: improved cryopreservation and cell-type specific impacts on energetics and proliferation. Cryobiology. 2010 Aug; 61(1):79-88.
    View in: PubMed
  59. Zhou B, Xu W, Herndon D, Tompkins R, Davis R, Xiao W, Wong WH, Toner M, Warren HS, Schoenfeld DA, Rahme L, McDonald-Smith GP, Hayden D, Mason P, Fagan S, Yu YM, Cobb JP, Remick DG, Mannick JA, Lederer JA, Gamelli RL, Silver GM, West MA, Shapiro MB, Smith R, Camp DG, Qian W, Storey J, Mindrinos M, Tibshirani R, Lowry S, Calvano S, Chaudry I, West MA, Cohen M, Moore EE, Johnson J, Moldawer LL, Baker HV, Efron PA, Balis UG, Billiar TR, Ochoa JB, Sperry JL, Miller-Graziano CL, De AK, Bankey PE, Finnerty CC, Jeschke MG, Minei JP, Arnoldo BD, Hunt JL, Horton J, Cobb JP, Brownstein B, Freeman B, Maier RV, Nathens AB, Cuschieri J, Gibran N, Klein M, O'Keefe G. Analysis of factorial time-course microarrays with application to a clinical study of burn injury. Proc Natl Acad Sci U S A. 2010 Jun 1; 107(22):9923-8.
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  60. Oakey J, Applegate RW, Arellano E, Di Carlo D, Graves SW, Toner M. Particle focusing in staged inertial microfluidic devices for flow cytometry. Anal Chem. 2010 May 1; 82(9):3862-7.
    View in: PubMed
  61. Stott SL, Lee RJ, Nagrath S, Yu M, Miyamoto DT, Ulkus L, Inserra EJ, Ulman M, Springer S, Nakamura Z, Moore AL, Tsukrov DI, Kempner ME, Dahl DM, Wu CL, Iafrate AJ, Smith MR, Tompkins RG, Sequist LV, Toner M, Haber DA, Maheswaran S. Isolation and characterization of circulating tumor cells from patients with localized and metastatic prostate cancer. Sci Transl Med. 2010 Mar 31; 2(25):25ra23.
    View in: PubMed
  62. Sitaula R, Fowler A, Toner M, Bhowmick S. A study of the effect of sorbitol on osmotic tolerance during partial desiccation of bovine sperm. Cryobiology. 2010 Jun; 60(3):331-6.
    View in: PubMed
  63. Bajpayee A, Edd JF, Chang A, Toner M. Concentration of glycerol in aqueous microdroplets by selective removal of water. Anal Chem. 2010 Feb 15; 82(4):1288-91.
    View in: PubMed
  64. Wolfer A, Wittner BS, Irimia D, Flavin RJ, Lupien M, Gunawardane RN, Meyer CA, Lightcap ES, Tamayo P, Mesirov JP, Liu XS, Shioda T, Toner M, Loda M, Brown M, Brugge JS, Ramaswamy S. MYC regulation of a "poor-prognosis" metastatic cancer cell state. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3698-703.
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  65. Chen GD, Alberts CJ, Rodriguez W, Toner M. Concentration and purification of human immunodeficiency virus type 1 virions by microfluidic separation of superparamagnetic nanoparticles. Anal Chem. 2010 Jan 15; 82(2):723-8.
    View in: PubMed
  66. Cho CH, Park J, Tilles AW, Berthiaume F, Toner M, Yarmush ML. Layered patterning of hepatocytes in co-culture systems using microfabricated stencils. Biotechniques. 2010 Jan; 48(1):47-52.
    View in: PubMed
  67. Chen C, Skog J, Hsu CH, Lessard RT, Balaj L, Wurdinger T, Carter BS, Breakefield XO, Toner M, Irimia D. Microfluidic isolation and transcriptome analysis of serum microvesicles. Lab Chip. 2010 Feb 21; 10(4):505-11.
    View in: PubMed
  68. Lee HJ, Elmoazzen H, Wright D, Biggers J, Rueda BR, Heo YS, Toner M, Toth TL. Ultra-rapid vitrification of mouse oocytes in low cryoprotectant concentrations. Reprod Biomed Online. 2010 Feb; 20(2):201-8.
    View in: PubMed
  69. Roach KL, King KR, Uygun BE, Kohane IS, Yarmush ML, Toner M. High throughput single cell bioinformatics. Biotechnol Prog. 2009 Nov-Dec; 25(6):1772-9.
    View in: PubMed
  70. Watkins N, Venkatesan BM, Toner M, Rodriguez W, Bashir R. A robust electrical microcytometer with 3-dimensional hydrofocusing. Lab Chip. 2009 Nov 21; 9(22):3177-84.
    View in: PubMed
  71. Haghgooie R, Toner M, Doyle PS. Squishy non-spherical hydrogel microparticles. Macromol Rapid Commun. 2010 Jan 18; 31(2):128-34.
    View in: PubMed
  72. Irimia D, Toner M. Spontaneous migration of cancer cells under conditions of mechanical confinement. Integr Biol (Camb). 2009 Sep; 1(8-9):506-12.
    View in: PubMed
  73. Wang S, Chen PC, Berthiaume F, Toner M, Jayaraman A, Yarmush ML. Dynamic effect of heat shock pretreatment on apoptotic responses to TNF-alpha in liver cells. J Biomech Eng. 2009 Jul; 131(7):071003.
    View in: PubMed
  74. Russom A, Irimia D, Toner M. Chemical gradient-mediated melting curve analysis for genotyping of SNPs. Electrophoresis. 2009 Jul; 30(14):2536-43.
    View in: PubMed
  75. Irimia D, Balázsi G, Agrawal N, Toner M. Adaptive-control model for neutrophil orientation in the direction of chemical gradients. Biophys J. 2009 May 20; 96(10):3897-916.
    View in: PubMed
  76. Elmoazzen HY, Lee GY, Li MW, McGinnis LK, Lloyd KC, Toner M, Biggers JD. Further optimization of mouse spermatozoa evaporative drying techniques. Cryobiology. 2009 Aug; 59(1):113-5.
    View in: PubMed
  77. Saenz J, Toner M, Risco R. Comparison between ideal and nonideal solution models for single-cell cryopreservation protocols. J Phys Chem B. 2009 Apr 9; 113(14):4853-64.
    View in: PubMed
  78. Edd JF, Humphry KJ, Irimia D, Weitz DA, Toner M. Nucleation and solidification in static arrays of monodisperse drops. Lab Chip. 2009 Jul 7; 9(13):1859-65.
    View in: PubMed
  79. Hwang DK, Oakey J, Toner M, Arthur JA, Anseth KS, Lee S, Zeiger A, Van Vliet KJ, Doyle PS. Stop-flow lithography for the production of shape-evolving degradable microgel particles. J Am Chem Soc. 2009 Apr 1; 131(12):4499-504.
    View in: PubMed
  80. Sitaula R, Elmoazzen H, Toner M, Bhowmick S. Desiccation tolerance in bovine sperm: a study of the effect of intracellular sugars and the supplemental roles of an antioxidant and a chelator. Cryobiology. 2009 Jun; 58(3):322-30.
    View in: PubMed
  81. Roach KL, King KR, Uygun K, Hand SC, Kohane IS, Yarmush ML, Toner M. High-throughput single cell arrays as a novel tool in biopreservation. Cryobiology. 2009 Jun; 58(3):315-21.
    View in: PubMed
  82. Di Carlo D, Edd JF, Humphry KJ, Stone HA, Toner M. Particle segregation and dynamics in confined flows. Phys Rev Lett. 2009 Mar 6; 102(9):094503.
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  83. Sequist LV, Nagrath S, Toner M, Haber DA, Lynch TJ. The CTC-chip: an exciting new tool to detect circulating tumor cells in lung cancer patients. J Thorac Oncol. 2009 Mar; 4(3):281-3.
    View in: PubMed
  84. Menze MA, Boswell L, Toner M, Hand SC. Occurrence of mitochondria-targeted Late Embryogenesis Abundant (LEA) gene in animals increases organelle resistance to water stress. J Biol Chem. 2009 Apr 17; 284(16):10714-9.
    View in: PubMed
  85. Cheng X, Gupta A, Chen C, Tompkins RG, Rodriguez W, Toner M. Enhancing the performance of a point-of-care CD4+ T-cell counting microchip through monocyte depletion for HIV/AIDS diagnostics. Lab Chip. 2009 May 21; 9(10):1357-64.
    View in: PubMed
  86. Guillemette MD, Cui B, Roy E, Gauvin R, Giasson CJ, Esch MB, Carrier P, Deschambeault A, Dumoulin M, Toner M, Germain L, Veres T, Auger FA. Surface topography induces 3D self-orientation of cells and extracellular matrix resulting in improved tissue function. Integr Biol (Camb). 2009 Feb; 1(2):196-204.
    View in: PubMed
  87. Moore RN, Dasgupta A, Rajaei N, Yarmush ML, Toner M, Larue L, Moghe PV. Enhanced differentiation of embryonic stem cells using co-cultivation with hepatocytes. Biotechnol Bioeng. 2008 Dec 15; 101(6):1332-43.
    View in: PubMed
  88. Kasuga K, Yang R, Porter TF, Agrawal N, Petasis NA, Irimia D, Toner M, Serhan CN. Rapid appearance of resolvin precursors in inflammatory exudates: novel mechanisms in resolution. J Immunol. 2008 Dec 15; 181(12):8677-87.
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  89. Ergenc AF, Li MW, Toner M, Biggers JD, Lloyd KC, Olgac N. Rotationally oscillating drill (Ros-Drill) for mouse ICSI without using mercury. Mol Reprod Dev. 2008 Dec; 75(12):1744-51.
    View in: PubMed
  90. Irimia D, Mindrinos M, Russom A, Xiao W, Wilhelmy J, Wang S, Heath JD, Kurn N, Tompkins RG, Davis RW, Toner M. Genome-wide transcriptome analysis of 150 cell samples. Integr Biol (Camb). 2009 Jan; 1(1):99-107.
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  91. Agrawal N, Toner M, Irimia D. Neutrophil migration assay from a drop of blood. Lab Chip. 2008 Dec; 8(12):2054-61.
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  92. Hsu CH, Di Carlo D, Chen C, Irimia D, Toner M. Microvortex for focusing, guiding and sorting of particles. Lab Chip. 2008 Dec; 8(12):2128-34.
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  93. Eroglu A, Bailey SE, Toner M, Toth TL. Successful cryopreservation of mouse oocytes by using low concentrations of trehalose and dimethylsulfoxide. Biol Reprod. 2009 Jan; 80(1):70-8.
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  94. Adams DR, Toner M, Langer R. Microflow and crack formation patterns in drying sessile droplets of liposomes suspended in trehalose solutions. Langmuir. 2008 Aug 5; 24(15):7688-97.
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  95. Maheswaran S, Sequist LV, Nagrath S, Ulkus L, Brannigan B, Collura CV, Inserra E, Diederichs S, Iafrate AJ, Bell DW, Digumarthy S, Muzikansky A, Irimia D, Settleman J, Tompkins RG, Lynch TJ, Toner M, Haber DA. Detection of mutations in EGFR in circulating lung-cancer cells. N Engl J Med. 2008 Jul 24; 359(4):366-77.
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  96. Edd JF, Di Carlo D, Humphry KJ, Köster S, Irimia D, Weitz DA, Toner M. Controlled encapsulation of single-cells into monodisperse picolitre drops. Lab Chip. 2008 Aug; 8(8):1262-4.
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  97. Park K, Jang J, Irimia D, Sturgis J, Lee J, Robinson JP, Toner M, Bashir R. 'Living cantilever arrays' for characterization of mass of single live cells in fluids. Lab Chip. 2008 Jul; 8(7):1034-41.
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  98. He X, Fowler A, Menze M, Hand S, Toner M. Desiccation kinetics and biothermodynamics of glass forming trehalose solutions in thin films. Ann Biomed Eng. 2008 Aug; 36(8):1428-39.
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  99. Kelly RT, Tang K, Irimia D, Toner M, Smith RD. Elastomeric microchip electrospray emitter for stable cone-jet mode operation in the nanoflow regime. Anal Chem. 2008 May 15; 80(10):3824-31.
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  100. Parekkadan B, Berdichevsky Y, Irimia D, Leeder A, Yarmush G, Toner M, Levine JB, Yarmush ML. Cell-cell interaction modulates neuroectodermal specification of embryonic stem cells. Neurosci Lett. 2008 Jun 20; 438(2):190-5.
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  101. He X, Park EY, Fowler A, Yarmush ML, Toner M. Vitrification by ultra-fast cooling at a low concentration of cryoprotectants in a quartz micro-capillary: a study using murine embryonic stem cells. Cryobiology. 2008 Jun; 56(3):223-32.
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  102. Russom A, Sethu P, Irimia D, Mindrinos MN, Calvano SE, Garcia I, Finnerty C, Tannahill C, Abouhamze A, Wilhelmy J, López MC, Baker HV, Herndon DN, Lowry SF, Maier RV, Davis RW, Moldawer LL, Tompkins RG, Toner M. Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients. Clin Chem. 2008 May; 54(5):891-900.
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  103. Di Carlo D, Edd JF, Irimia D, Tompkins RG, Toner M. Equilibrium separation and filtration of particles using differential inertial focusing. Anal Chem. 2008 Mar 15; 80(6):2204-11.
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  104. Toner M, Tompkins RG. Invention, innovation, entrepreneurship in academic medical centers. Surgery. 2008 Feb; 143(2):168-71.
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  105. Park J, Li Y, Berthiaume F, Toner M, Yarmush ML, Tilles AW. Radial flow hepatocyte bioreactor using stacked microfabricated grooved substrates. Biotechnol Bioeng. 2008 Feb 1; 99(2):455-67.
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  106. Nagrath S, Sequist LV, Maheswaran S, Bell DW, Irimia D, Ulkus L, Smith MR, Kwak EL, Digumarthy S, Muzikansky A, Ryan P, Balis UJ, Tompkins RG, Haber DA, Toner M. Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature. 2007 Dec 20; 450(7173):1235-9.
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  107. King KR, Wang S, Jayaraman A, Yarmush ML, Toner M. Microfluidic flow-encoded switching for parallel control of dynamic cellular microenvironments. Lab Chip. 2008 Jan; 8(1):107-16.
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  108. Di Carlo D, Irimia D, Tompkins RG, Toner M. Continuous inertial focusing, ordering, and separation of particles in microchannels. Proc Natl Acad Sci U S A. 2007 Nov 27; 104(48):18892-7.
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  109. Adams DR, Toner M, Langer R. Role of trehalose in prevention of giant vesicle adsorption and encapsulated solute leakage in anhydrobiotic preservation. Langmuir. 2007 Dec 18; 23(26):13013-23.
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  110. Toner M. Development of new therapeutic applications using microfluidics. J Vis Exp. 2007; (8):323.
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  111. Li MW, Biggers JD, Toner M, Griffey SM, Lloyd KC. Phenotypic analysis of C57BL/6J and FVB/NJ mice generated using evaporatively dried spermatozoa. Comp Med. 2007 Oct; 57(5):469-75.
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  112. Parekkadan B, Sethu P, van Poll D, Yarmush ML, Toner M. Osmotic selection of human mesenchymal stem/progenitor cells from umbilical cord blood. Tissue Eng. 2007 Oct; 13(10):2465-73.
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  113. Kotz K, Cheng X, Toner M. PDMS device fabrication and surface modification. J Vis Exp. 2007; (8):319.
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  114. Kotz K, Cheng X, Toner M. Cell capture using a microfluidic device. J Vis Exp. 2007; (8):320.
    View in: PubMed
  115. Irimia D, Charras G, Agrawal N, Mitchison T, Toner M. Polar stimulation and constrained cell migration in microfluidic channels. Lab Chip. 2007 Dec; 7(12):1783-90.
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  116. Risco R, Elmoazzen H, Doughty M, He X, Toner M. Thermal performance of quartz capillaries for vitrification. Cryobiology. 2007 Dec; 55(3):222-9.
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  117. Cheng X, Irimia D, Dixon M, Ziperstein JC, Demirci U, Zamir L, Tompkins RG, Toner M, Rodriguez WR. A microchip approach for practical label-free CD4+ T-cell counting of HIV-infected subjects in resource-poor settings. J Acquir Immune Defic Syndr. 2007 Jul 1; 45(3):257-61.
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  118. Park J, Cho CH, Parashurama N, Li Y, Berthiaume F, Toner M, Tilles AW, Yarmush ML. Microfabrication-based modulation of embryonic stem cell differentiation. Lab Chip. 2007 Aug; 7(8):1018-28.
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  119. Cheng X, Liu YS, Irimia D, Demirci U, Yang L, Zamir L, Rodríguez WR, Toner M, Bashir R. Cell detection and counting through cell lysate impedance spectroscopy in microfluidic devices. Lab Chip. 2007 Jun; 7(6):746-55.
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  120. Cho CH, Park J, Nagrath D, Tilles AW, Berthiaume F, Toner M, Yarmush ML. Oxygen uptake rates and liver-specific functions of hepatocyte and 3T3 fibroblast co-cultures. Biotechnol Bioeng. 2007 May 1; 97(1):188-99.
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  121. Li MW, Biggers JD, Elmoazzen HY, Toner M, McGinnis L, Lloyd KC. Long-term storage of mouse spermatozoa after evaporative drying. Reproduction. 2007 May; 133(5):919-29.
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  122. Pregibon DC, Toner M, Doyle PS. Multifunctional encoded particles for high-throughput biomolecule analysis. Science. 2007 Mar 9; 315(5817):1393-6.
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  123. Kidambi S, Sheng L, Yarmush ML, Toner M, Lee I, Chan C. Patterned co-culture of primary hepatocytes and fibroblasts using polyelectrolyte multilayer templates. Macromol Biosci. 2007 Mar 8; 7(3):344-53.
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  124. Mikos AG, Herring SW, Ochareon P, Elisseeff J, Lu HH, Kandel R, Schoen FJ, Toner M, Mooney D, Atala A, Van Dyke ME, Kaplan D, Vunjak-Novakovic G. Engineering complex tissues. Tissue Eng. 2006 Dec; 12(12):3307-39.
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  125. Cheng X, Irimia D, Dixon M, Sekine K, Demirci U, Zamir L, Tompkins RG, Rodriguez W, Toner M. A microfluidic device for practical label-free CD4(+) T cell counting of HIV-infected subjects. Lab Chip. 2007 Feb; 7(2):170-8.
    View in: PubMed
  126. Shinoda M, Tilles AW, Kobayashi N, Wakabayashi G, Takayanagi A, Totsugawa T, Harada H, Obara H, Suganuma K, Berthiaume F, Shimazu M, Shimizu N, Tanaka N, Kitajima M, Tompkins RG, Toner M, Yarmush ML. A bioartificial liver device secreting interleukin-1 receptor antagonist for the treatment of hepatic failure in rats. J Surg Res. 2007 Jan; 137(1):130-40.
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  127. van Poll D, Sokmensuer C, Ahmad N, Tilles AW, Berthiaume F, Toner M, Yarmush ML. Elevated hepatocyte-specific functions in fetal rat hepatocytes co-cultured with adult rat hepatocytes. Tissue Eng. 2006 Oct; 12(10):2965-73.
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  128. King KR, Wang S, Irimia D, Jayaraman A, Toner M, Yarmush ML. A high-throughput microfluidic real-time gene expression living cell array. Lab Chip. 2007 Jan; 7(1):77-85.
    View in: PubMed
  129. Murthy SK, Sethu P, Vunjak-Novakovic G, Toner M, Radisic M. Size-based microfluidic enrichment of neonatal rat cardiac cell populations. Biomed Microdevices. 2006 Sep; 8(3):231-7.
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  130. Sethu P, Moldawer LL, Mindrinos MN, Scumpia PO, Tannahill CL, Wilhelmy J, Efron PA, Brownstein BH, Tompkins RG, Toner M. Microfluidic isolation of leukocytes from whole blood for phenotype and gene expression analysis. Anal Chem. 2006 Aug 1; 78(15):5453-61.
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  131. Norris MM, Aksan A, Sugimachi K, Toner M. 3-O-methyl-D-glucose improves desiccation tolerance of keratinocytes. Tissue Eng. 2006 Jul; 12(7):1873-9.
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  132. Kane BJ, Zinner MJ, Yarmush ML, Toner M. Liver-specific functional studies in a microfluidic array of primary mammalian hepatocytes. Anal Chem. 2006 Jul 1; 78(13):4291-8.
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  133. Sekine K, Revzin A, Tompkins RG, Toner M. Panning of multiple subsets of leukocytes on antibody-decorated poly(ethylene) glycol-coated glass slides. J Immunol Methods. 2006 Jun 30; 313(1-2):96-109.
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  134. Rajagopalan P, Shen CJ, Berthiaume F, Tilles AW, Toner M, Yarmush ML. Polyelectrolyte nano-scaffolds for the design of layered cellular architectures. Tissue Eng. 2006 Jun; 12(6):1553-63.
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  135. Pregibon DC, Toner M, Doyle PS. Magnetically and biologically active bead-patterned hydrogels. Langmuir. 2006 May 23; 22(11):5122-8.
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  136. Irimia D, Geba DA, Toner M. Universal microfluidic gradient generator. Anal Chem. 2006 May 15; 78(10):3472-7.
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  137. Shinoda M, Tilles AW, Wakabayashi G, Takayanagi A, Harada H, Obara H, Suganuma K, Berthiaume F, Shimazu M, Shimizu N, Kitajima M, Tompkins RG, Toner M, Yarmush ML. Treatment of fulminant hepatic failure in rats using a bioartificial liver device containing porcine hepatocytes producing interleukin-1 receptor antagonist. Tissue Eng. 2006 May; 12(5):1313-23.
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  138. Madihally SV, Pantelogianis A, Toner M. Antiproteolytic action of orally delivered insulin using pH-responsive hydrogels in a rat burn model. J Surg Res. 2006 Sep; 135(1):187-94.
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  139. Vianello F, Papeta N, Chen T, Kraft P, White N, Hart WK, Kircher MF, Swart E, Rhee S, Palù G, Irimia D, Toner M, Weissleder R, Poznansky MC. Murine B16 melanomas expressing high levels of the chemokine stromal-derived factor-1/CXCL12 induce tumor-specific T cell chemorepulsion and escape from immune control. J Immunol. 2006 Mar 1; 176(5):2902-14.
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  140. Sugimachi K, Roach KL, Rhoads DB, Tompkins RG, Toner M. Nonmetabolizable glucose compounds impart cryotolerance to primary rat hepatocytes. Tissue Eng. 2006 Mar; 12(3):579-88.
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  141. Irimia D, Toner M. Cell handling using microstructured membranes. Lab Chip. 2006 Mar; 6(3):345-52.
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  142. Irimia D, Liu SY, Tharp WG, Samadani A, Toner M, Poznansky MC. Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients. Lab Chip. 2006 Feb; 6(2):191-8.
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  143. Elliott GD, Liu XH, Cusick JL, Menze M, Vincent J, Witt T, Hand S, Toner M. Trehalose uptake through P2X7 purinergic channels provides dehydration protection. Cryobiology. 2006 Feb; 52(1):114-27.
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  144. Stacy R, Eroglu A, Fowler A, Biggers J, Toner M. Thermal characterization of Nakagata's mouse sperm freezing protocol. Cryobiology. 2006 Feb; 52(1):99-107.
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  145. Fowler A, Toner M. Cryo-injury and biopreservation. Ann N Y Acad Sci. 2005 Dec; 1066:119-35.
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  146. Sethu P, Sin A, Toner M. Microfluidic diffusive filter for apheresis (leukapheresis). Lab Chip. 2006 Jan; 6(1):83-9.
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  147. Sin A, Murthy SK, Revzin A, Tompkins RG, Toner M. Enrichment using antibody-coated microfluidic chambers in shear flow: model mixtures of human lymphocytes. Biotechnol Bioeng. 2005 Sep 30; 91(7):816-26.
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  148. Liu XH, Aksan A, Menze MA, Hand SC, Toner M. Trehalose loading through the mitochondrial permeability transition pore enhances desiccation tolerance in rat liver mitochondria. Biochim Biophys Acta. 2005 Nov 10; 1717(1):21-6.
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  149. Rajagopalan P, Berthiaume F, Tilles AW, Toner M, Yarmush ML. Selective enhancement of cytochrome p-450 activity in rat hepatocytes by in vitro heat shock. Tissue Eng. 2005 Sep-Oct; 11(9-10):1527-34.
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  150. Park J, Berthiaume F, Toner M, Yarmush ML, Tilles AW. Microfabricated grooved substrates as platforms for bioartificial liver reactors. Biotechnol Bioeng. 2005 Jun 5; 90(5):632-44.
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  151. McGinnis LK, Zhu L, Lawitts JA, Bhowmick S, Toner M, Biggers JD. Mouse sperm desiccated and stored in trehalose medium without freezing. Biol Reprod. 2005 Oct; 73(4):627-33.
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  152. Eroglu A, Elliott G, Wright DL, Toner M, Toth TL. Progressive elimination of microinjected trehalose during mouse embryonic development. Reprod Biomed Online. 2005 Apr; 10(4):503-10.
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  153. Aksan A, Morris SC, Toner M. Analysis of desiccation and vitrification characteristics of carbohydrate films by shear-wave resonators. Langmuir. 2005 Mar 29; 21(7):2847-54.
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  154. Cobb JP, Mindrinos MN, Miller-Graziano C, Calvano SE, Baker HV, Xiao W, Laudanski K, Brownstein BH, Elson CM, Hayden DL, Herndon DN, Lowry SF, Maier RV, Schoenfeld DA, Moldawer LL, Davis RW, Tompkins RG, Baker HV, Bankey P, Billiar T, Brownstein BH, Calvano SE, Camp D, Chaudry I, Cobb JP, Davis RW, Elson CM, Freeman B, Gamelli R, Gibran N, Harbrecht B, Hayden DL, Heagy W, Heimbach D, Herndon DN, Horton J, Hunt J, Laudanski K, Lederer J, Lowry SF, Maier RV, Mannick J, McKinley B, Miller-Graziano C, Mindrinos MN, Minei J, Moldawer LL, Moore E, Moore F, Munford R, Nathens A, O'keefe G, Purdue G, Rahme L, Remick D, Sailors M, Schoenfeld DA, Shapiro M, Silver G, Smith R, Stephanopoulos G, Stormo G, Tompkins RG, Toner M, Warren S, West M, Wolfe S, Xiao W, Young V. Application of genome-wide expression analysis to human health and disease. Proc Natl Acad Sci U S A. 2005 Mar 29; 102(13):4801-6.
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  155. Downing BR, Cornwell K, Toner M, Pins GD. The influence of microtextured basal lamina analog topography on keratinocyte function and epidermal organization. J Biomed Mater Res A. 2005 Jan 1; 72(1):47-56.
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  156. Toner M, Irimia D. Blood-on-a-chip. Annu Rev Biomed Eng. 2005; 7:77-103.
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  157. Sosef MN, Baust JM, Sugimachi K, Fowler A, Tompkins RG, Toner M. Cryopreservation of isolated primary rat hepatocytes: enhanced survival and long-term hepatospecific function. Ann Surg. 2005 Jan; 241(1):125-33.
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  158. Murthy SK, Sin A, Tompkins RG, Toner M. Effect of flow and surface conditions on human lymphocyte isolation using microfluidic chambers. Langmuir. 2004 Dec 21; 20(26):11649-55.
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  159. Hamaratoglu F, Eroglu A, Toner M, Sadler KC. Cryopreservation of starfish oocytes. Cryobiology. 2005 Feb; 50(1):38-47.
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  160. Sethu P, Anahtar M, Moldawer LL, Tompkins RG, Toner M. Continuous flow microfluidic device for rapid erythrocyte lysis. Anal Chem. 2004 Nov 1; 76(21):6247-53.
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  161. Chan C, Berthiaume F, Nath BD, Tilles AW, Toner M, Yarmush ML. Hepatic tissue engineering for adjunct and temporary liver support: critical technologies. Liver Transpl. 2004 Nov; 10(11):1331-42.
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  162. Irimia D, Tompkins RG, Toner M. Single-cell chemical lysis in picoliter-scale closed volumes using a microfabricated device. Anal Chem. 2004 Oct 15; 76(20):6137-43.
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  163. Revzin A, Sekine K, Sin A, Tompkins RG, Toner M. Development of a microfabricated cytometry platform for characterization and sorting of individual leukocytes. Lab Chip. 2005 Jan; 5(1):30-7.
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  164. Wright DL, Eroglu A, Toner M, Toth TL. Use of sugars in cryopreserving human oocytes. Reprod Biomed Online. 2004 Aug; 9(2):179-86.
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  165. Thompson DM, King KR, Wieder KJ, Toner M, Yarmush ML, Jayaraman A. Dynamic gene expression profiling using a microfabricated living cell array. Anal Chem. 2004 Jul 15; 76(14):4098-103.
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  166. Aksan A, Toner M. Isothermal desiccation and vitrification kinetics of trehalose-dextran solutions. Langmuir. 2004 Jun 22; 20(13):5521-9.
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  167. Buchanan SS, Gross SA, Acker JP, Toner M, Carpenter JF, Pyatt DW. Cryopreservation of stem cells using trehalose: evaluation of the method using a human hematopoietic cell line. Stem Cells Dev. 2004 Jun; 13(3):295-305.
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  168. Revzin A, Rajagopalan P, Tilles AW, Berthiaume F, Yarmush ML, Toner M. Designing a hepatocellular microenvironment with protein microarraying and poly(ethylene glycol) photolithography. Langmuir. 2004 Apr 13; 20(8):2999-3005.
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  169. Sugimachi K, Sosef MN, Baust JM, Fowler A, Tompkins RG, Toner M. Long-term function of cryopreserved rat hepatocytes in a coculture system. Cell Transplant. 2004; 13(2):187-95.
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  170. Acker JP, Lu XM, Young V, Cheley S, Bayley H, Fowler A, Toner M. Measurement of trehalose loading of mammalian cells porated with a metal-actuated switchable pore. Biotechnol Bioeng. 2003 Jun 5; 82(5):525-32.
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  171. Shito M, Tilles AW, Tompkins RG, Yarmush ML, Toner M. Efficacy of an extracorporeal flat-plate bioartificial liver in treating fulminant hepatic failure. J Surg Res. 2003 May 1; 111(1):53-62.
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  172. Eroglu A, Lawitts JA, Toner M, Toth TL. Quantitative microinjection of trehalose into mouse oocytes and zygotes, and its effect on development. Cryobiology. 2003 Apr; 46(2):121-34.
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  173. Madibally SV, Solomon V, Mitchell RN, Van De Water L, Yarmush ML, Toner M. Influence of insulin therapy on burn wound healing in rats. J Surg Res. 2003 Feb; 109(2):92-100.
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  174. Gilman AG, Simon MI, Bourne HR, Harris BA, Long R, Ross EM, Stull JT, Taussig R, Bourne HR, Arkin AP, Cobb MH, Cyster JG, Devreotes PN, Ferrell JE, Fruman D, Gold M, Weiss A, Stull JT, Berridge MJ, Cantley LC, Catterall WA, Coughlin SR, Olson EN, Smith TF, Brugge JS, Botstein D, Dixon JE, Hunter T, Lefkowitz RJ, Pawson AJ, Sternberg PW, Varmus H, Subramaniam S, Sinkovits RS, Li J, Mock D, Ning Y, Saunders B, Sternweis PC, Hilgemann D, Scheuermann RH, DeCamp D, Hsueh R, Lin KM, Ni Y, Seaman WE, Simpson PC, O'Connell TD, Roach T, Simon MI, Choi S, Eversole-Cire P, Fraser I, Mumby MC, Zhao Y, Brekken D, Shu H, Meyer T, Chandy G, Heo WD, Liou J, O'Rourke N, Verghese M, Mumby SM, Han H, Brown HA, Forrester JS, Ivanova P, Milne SB, Casey PJ, Harden TK, Arkin AP, Doyle J, Gray ML, Meyer T, Michnick S, Schmidt MA, Toner M, Tsien RY, Natarajan M, Ranganathan R, Sambrano GR. Overview of the Alliance for Cellular Signaling. Nature. 2002 Dec 12; 420(6916):703-6.
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  175. Bhowmick S, Zhu L, McGinnis L, Lawitts J, Nath BD, Toner M, Biggers J. Desiccation tolerance of spermatozoa dried at ambient temperature: production of fetal mice. Biol Reprod. 2003 May; 68(5):1779-86.
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  176. Madihally SV, Toner M, Yarmush ML, Mitchell RN. Interferon gamma modulates trauma-induced muscle wasting and immune dysfunction. Ann Surg. 2002 Nov; 236(5):649-57.
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  177. Bhowmick P, Eroglu A, Wright DL, Toner M, Toth TL. Osmometric behavior of mouse oocytes in the presence of different intracellular sugars. Cryobiology. 2002 Oct; 45(2):183-7.
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  178. Voldman J, Gray ML, Toner M, Schmidt MA. A microfabrication-based dynamic array cytometer. Anal Chem. 2002 Aug 15; 74(16):3984-90.
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  179. Balis UJ, Yarmush ML, Toner M. Bioartificial liver process monitoring and control systems with integrated systems capability. Tissue Eng. 2002 Jul; 8(3):483-98.
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  180. Li Jeon N, Baskaran H, Dertinger SK, Whitesides GM, Van de Water L, Toner M. Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device. Nat Biotechnol. 2002 Aug; 20(8):826-30.
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  181. Chan C, Berthiaume F, Washizu J, Toner M, Yarmush ML. Metabolic pre-conditioning of cultured cells in physiological levels of insulin: generating resistance to the lipid-accumulating effects of plasma in hepatocytes. Biotechnol Bioeng. 2002 Jun 30; 78(7):753-60.
    View in: PubMed
  182. Solomon V, Madihally S, Mitchell RN, Yarmush M, Toner M. Antiproteolytic action of insulin in burn-injured rats. J Surg Res. 2002 Jun 15; 105(2):234-42.
    View in: PubMed
  183. Erdag G, Eroglu A, Morgan J, Toner M. Cryopreservation of fetal skin is improved by extracellular trehalose. Cryobiology. 2002 Jun; 44(3):218-28.
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  184. Kocsis JD, Toner M, Anderson DK, Brockbank K, Germain L, Lee RC, Ratner BD. Storage and translational issues in reparative medicine: breakout session summary. Ann N Y Acad Sci. 2002 Jun; 961:276-8.
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  185. Toner M, Kocsis J. Storage and translational issues in reparative medicine. Ann N Y Acad Sci. 2002 Jun; 961:258-62.
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  186. Chen T, Bhowmick S, Sputtek A, Fowler A, Toner M. The glass transition temperature of mixtures of trehalose and hydroxyethyl starch. Cryobiology. 2002 Jun; 44(3):301-6.
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  187. Eroglu A, Toner M, Toth TL. Beneficial effect of microinjected trehalose on the cryosurvival of human oocytes. Fertil Steril. 2002 Jan; 77(1):152-8.
    View in: PubMed
  188. Tilles AW, Berthiaume F, Yarmush ML, Tompkins RG, Toner M. Bioengineering of liver assist devices. J Hepatobiliary Pancreat Surg. 2002; 9(6):686-96.
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  189. Cadarette BS, Sawka MN, Toner MM, Pandolf KB. Aerobic fitness and the hypohydration response to exercise-heat stress. Aviat Space Environ Med. 1984 Jun; 55(6):507-12.
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