Harvard Catalyst Profiles

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Mohammed Asmal, M.D., Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Esrick EB, Manis JP, Daley H, Baricordi C, Trébéden-Negre H, Pierciey FJ, Armant M, Nikiforow S, Heeney MM, London WB, Biasco L, Asmal M, Williams DA, Biffi A. Successful hematopoietic stem cell mobilization and apheresis collection using plerixafor alone in sickle cell patients. Blood Adv. 2018 10 09; 2(19):2505-2512. PMID: 30282642.
  2. Thompson AA, Walters MC, Kwiatkowski J, Rasko JEJ, Ribeil JA, Hongeng S, Magrin E, Schiller GJ, Payen E, Semeraro M, Moshous D, Lefrere F, Puy H, Bourget P, Magnani A, Caccavelli L, Diana JS, Suarez F, Monpoux F, Brousse V, Poirot C, Brouzes C, Meritet JF, Pondarré C, Beuzard Y, Chrétien S, Lefebvre T, Teachey DT, Anurathapan U, Ho PJ, von Kalle C, Kletzel M, Vichinsky E, Soni S, Veres G, Negre O, Ross RW, Davidson D, Petrusich A, Sandler L, Asmal M, Hermine O, De Montalembert M, Hacein-Bey-Abina S, Blanche S, Leboulch P, Cavazzana M. Gene Therapy in Patients with Transfusion-Dependent ß-Thalassemia. N Engl J Med. 2018 04 19; 378(16):1479-1493. PMID: 29669226.
    Citations: 9     Fields:    Translation:HumansCellsCTClinical Trials
  3. Trevejo JM, Asmal M, Vingerhoets J, Polo R, Robertson S, Jiang Y, Kieffer TL, Leopold L. Pimodivir treatment in adult volunteers experimentally inoculated with live influenza virus: a Phase IIa, randomized, double-blind, placebo-controlled study. Antivir Ther. 2018; 23(4):335-344. PMID: 29244026.
    Citations: 2     Fields:    
  4. Krebs KC, Tian M, Asmal M, Ling B, Nelson K, Henry K, Gibson R, Li Y, Han W, Shattock RJ, Veazey RS, Letvin N, Arts EJ, Gao Y. Infection of rhesus macaques with a pool of simian immunodeficiency virus with the envelope genes from acute HIV-1 infections. AIDS Res Ther. 2016 11 25; 13(1):41. PMID: 27906032.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  5. Asmal M, Lane S, Tian M, Nickel G, Venner C, Dirk B, Dikeakos J, Luedemann C, Mach L, Balachandran H, Buzby A, Rao S, Letvin N, Gao Y, Arts EJ. Pathogenic infection of Rhesus macaques by an evolving SIV-HIV derived from CCR5-using envelope genes of acute HIV-1 infections. Virology. 2016 12; 499:298-312. PMID: 27723488.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  6. Cohen JM, Lederer PA, Russell-Goldman E, Sampson CE, Lin JY, Ho AW, Asmal M. An 86-Year-Old Man With Bilateral Chronic Wounds of the Legs. Clin Infect Dis. 2015 Oct 1; 61(7):1199-200. PMID: 26343054.
  7. Cohen JM, Lederer PA, Russell-Goldman E, Sampson CE, Lin JY, Ho AW, Asmal M. Photo quiz. An 86-Year-Old Man With Bilateral Chronic Wounds of the Legs. Bilateral invasive squamous cell carcinomas (Marjolin ulcers). Clin Infect Dis. 2015 Oct 01; 61(7):1147, 1199-200. PMID: 26343053.
    Citations:    Fields:    Translation:Humans
  8. Asmal M, Luedemann C, Lavine CL, Mach LV, Balachandran H, Brinkley C, Denny TN, Lewis MG, Anderson H, Pal R, Sok D, Le K, Pauthner M, Hahn BH, Shaw GM, Seaman MS, Letvin NL, Burton DR, Sodroski JG, Haynes BF, Santra S. Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes. Virology. 2015 Jan 15; 475:37-45. PMID: 25462344.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  9. Di Bisceglie AM, Sulkowski M, Gane E, Jacobson IM, Nelson D, DeSouza C, Alves K, George S, Kieffer T, Zhang EZ, Kauffman R, Asmal M, Koziel MJ. VX-222, a non-nucleoside NS5B polymerase inhibitor, in telaprevir-based regimens for genotype 1 hepatitis C virus infection. Eur J Gastroenterol Hepatol. 2014 Jul; 26(7):761-73. PMID: 24901821.
    Citations: 2     Fields:    Translation:HumansCellsCTClinical Trials
  10. Kolodkin-Gal D, Hulot SL, Korioth-Schmitz B, Gombos RB, Zheng Y, Owuor J, Lifton MA, Ayeni C, Najarian RM, Yeh WW, Asmal M, Zamir G, Letvin NL. Efficiency of cell-free and cell-associated virus in mucosal transmission of human immunodeficiency virus type 1 and simian immunodeficiency virus. J Virol. 2013 Dec; 87(24):13589-97. PMID: 24109227.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  11. Asmal M, Letvin NL, Geiben-Lynn R. Natural Killer cell-dependent and non-dependent anti-viral activity of 2-Cys Peroxiredoxin against HIV. Int Trends Immun. 2013 Oct; 1(4):69-77. PMID: 24244928.
    Citations: 2     
  12. Asmal M, Whitney JB, Luedemann C, Carville A, Steen R, Letvin NL, Geiben-Lynn R. In vivo anti-HIV activity of the heparin-activated serine protease inhibitor antithrombin III encapsulated in lymph-targeting immunoliposomes. PLoS One. 2012; 7(11):e48234. PMID: 23133620.
    Citations: 6     Fields:    Translation:AnimalsCells
  13. Asmal M, Seaman M, Lin W, Chung RT, Letvin NL, Geiben-Lynn R. Inhibition of HCV by the serpin antithrombin III. Virol J. 2012 Oct 02; 9:226. PMID: 23031791.
    Citations: 5     Fields:    Translation:HumansCells
  14. Flatz L, Cheng C, Wang L, Foulds KE, Ko SY, Kong WP, Roychoudhuri R, Shi W, Bao S, Todd JP, Asmal M, Shen L, Donaldson M, Schmidt SD, Gall JG, Pinschewer DD, Letvin NL, Rao S, Mascola JR, Roederer M, Nabel GJ. Gene-based vaccination with a mismatched envelope protects against simian immunodeficiency virus infection in nonhuman primates. J Virol. 2012 Aug; 86(15):7760-70. PMID: 22593152.
    Citations: 18     Fields:    Translation:AnimalsCells
  15. Gnanakaran S, Bhattacharya T, Daniels M, Keele BF, Hraber PT, Lapedes AS, Shen T, Gaschen B, Krishnamoorthy M, Li H, Decker JM, Salazar-Gonzalez JF, Wang S, Jiang C, Gao F, Swanstrom R, Anderson JA, Ping LH, Cohen MS, Markowitz M, Goepfert PA, Saag MS, Eron JJ, Hicks CB, Blattner WA, Tomaras GD, Asmal M, Letvin NL, Gilbert PB, Decamp AC, Magaret CA, Schief WR, Ban YE, Zhang M, Soderberg KA, Sodroski JG, Haynes BF, Shaw GM, Hahn BH, Korber B. Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections. PLoS Pathog. 2011 Sep; 7(9):e1002209. PMID: 21980282.
    Citations: 59     Fields:    Translation:CellsCTClinical Trials
  16. Asmal M, Hellmann I, Liu W, Keele BF, Perelson AS, Bhattacharya T, Gnanakaran S, Daniels M, Haynes BF, Korber BT, Hahn BH, Shaw GM, Letvin NL. A signature in HIV-1 envelope leader peptide associated with transition from acute to chronic infection impacts envelope processing and infectivity. PLoS One. 2011; 6(8):e23673. PMID: 21876761.
    Citations: 27     Fields:    Translation:HumansCells
  17. Sun Y, Asmal M, Lane S, Permar SR, Schmidt SD, Mascola JR, Letvin NL. Antibody-dependent cell-mediated cytotoxicity in simian immunodeficiency virus-infected rhesus monkeys. J Virol. 2011 Jul; 85(14):6906-12. PMID: 21593181.
    Citations: 31     Fields:    Translation:AnimalsCells
  18. Letvin NL, Rao SS, Montefiori DC, Seaman MS, Sun Y, Lim SY, Yeh WW, Asmal M, Gelman RS, Shen L, Whitney JB, Seoighe C, Lacerda M, Keating S, Norris PJ, Hudgens MG, Gilbert PB, Buzby AP, Mach LV, Zhang J, Balachandran H, Shaw GM, Schmidt SD, Todd JP, Dodson A, Mascola JR, Nabel GJ. Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys. Sci Transl Med. 2011 May 04; 3(81):81ra36. PMID: 21543722.
    Citations: 111     Fields:    Translation:HumansAnimalsCells
  19. Whitney JB, Asmal M, Geiben-Lynn R. Serpin induced antiviral activity of prostaglandin synthetase-2 against HIV-1 replication. PLoS One. 2011 Apr 12; 6(4):e18589. PMID: 21533265.
    Citations: 10     Fields:    Translation:Cells
  20. Asmal M, Sun Y, Lane S, Yeh W, Schmidt SD, Mascola JR, Letvin NL. Antibody-dependent cell-mediated viral inhibition emerges after simian immunodeficiency virus SIVmac251 infection of rhesus monkeys coincident with gp140-binding antibodies and is effective against neutralization-resistant viruses. J Virol. 2011 Jun; 85(11):5465-75. PMID: 21450829.
    Citations: 30     Fields:    Translation:AnimalsCells
  21. Yeh WW, Rahman I, Hraber P, Coffey RT, Nevidomskyte D, Giri A, Asmal M, Miljkovic S, Daniels M, Whitney JB, Keele BF, Hahn BH, Korber BT, Shaw GM, Seaman MS, Letvin NL. Autologous neutralizing antibodies to the transmitted/founder viruses emerge late after simian immunodeficiency virus SIVmac251 infection of rhesus monkeys. J Virol. 2010 Jun; 84(12):6018-32. PMID: 20357097.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  22. Yeh WW, Jaru-Ampornpan P, Nevidomskyte D, Asmal M, Rao SS, Buzby AP, Montefiori DC, Korber BT, Letvin NL. Partial protection of Simian immunodeficiency virus (SIV)-infected rhesus monkeys against superinfection with a heterologous SIV isolate. J Virol. 2009 Mar; 83(6):2686-96. PMID: 19129440.
    Citations: 24     Fields:    Translation:AnimalsCells
  23. Asmal M, Factor RE, Walensky RP. Photo quiz. An HIV-infected man with an upset stomach. Clin Infect Dis. 2008 Oct 01; 47(7):935-6; 979-80. PMID: 18778229.
    Citations: 1     Fields:    Translation:Humans
  24. Asmal M. Nocardia cerebral-pulmonary disease in an HIV infected patient. 2007.
  25. Colgan J, Asmal M, Yu B, Luban J. Cyclophilin A-deficient Mice are Resistant to Immunosuppression by Cyclosporine. Journal of Immunology. 2005; 164(10):6030 - 6038.
  26. Colgan J, Asmal M, Yu B, Luban J. Cyclophilin A-deficient mice are resistant to immunosuppression by cyclosporine. J Immunol. 2005 May 15; 174(10):6030-8. PMID: 15879096.
    Citations: 28     Fields:    Translation:AnimalsCells
  27. Colgan J, Asmal M, Neagu M, Yu B, Schneidkraut J, Lee Y, Sokolskaja E, Andreotti A, Luban J. Cyclophilin A regulates TCR signal strength in CD4+ T cells via a proline-directed conformational switch in Itk. Immunity. 2004 Aug; 21(2):189-201. PMID: 15308100.
    Citations: 59     Fields:    Translation:AnimalsCells
  28. Asmal M, Suri M, Ruzal-Shapiro CB, Baxi LV. Non-immune hydrops and superior vena cava syndrome due to diaphragmatic hernia in one twin. Fetal Diagn Ther. 2004 Jul-Aug; 19(4):377-80. PMID: 15192301.
    Citations:    Fields:    Translation:Humans
  29. Asmal M, Colgan J, Naef F, Yu B, Lee Y, Magnasco M, Luban J. Production of ribosome components in effector CD4+ T cells is accelerated by TCR stimulation and coordinated by ERK-MAPK. Immunity. 2003 Oct; 19(4):535-48. PMID: 14563318.
    Citations: 11     Fields:    Translation:AnimalsCells
  30. Asmal M, Luban J. Regulation of the Translational Machinery in Stimulated T-helper Cells. 2002.
  31. Asmal M. Characterization of the Ppia -/- Mouse and The Identification of a Family of Ribosomal Regulatory Proteins in T-helper 2 Cells. 2001.
  32. Colgan J, Asmal M, Luban J. Isolation, characterization and targeted disruption of mouse ppia: cyclophilin A is not essential for mammalian cell viability. Genomics. 2000 Sep 01; 68(2):167-78. PMID: 10964515.
    Citations: 18     Fields:    Translation:AnimalsCells
  33. Asmal AC, Asmal M. Consumption, Population and Sustainability. Chapman A, Petersen R, Smith B, editors. 2000; 157 - 166.
  34. Asmal M, Colgan J, Luban J. Conditional Viability, Haploid-Insufficient Growth and T-cell Hyperactivity in Cyclophilin A-Deficient Mice. 1999.
  35. Asmal M, Colgan J, Luban L. Haplo-Insufficient Growth and Premature Fibroblast Senescence in Cyclophilin A-Deficient Mice. American Society for Clinical Investigation. 1999.
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.