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profileJohn Weber Denninger, M.D.,PH.D.

TitleInstructor in Psychiatry
InstitutionMassachusetts General Hospital
DepartmentPsychiatry
AddressMassachusetts General Hospital
Depression Clinical and Research Program, Suite 401
50 Staniford Street
Boston MA 02114
Phone617/726-2985
Fax617/724-3028
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Dossett ML, Korzenik JR, Baim M, Denninger JW, Mehta DH. A Case Report of Improvement in Crohn's Disease-related Symptoms Following Participation in a Comprehensive Mind-Body Program. Glob Adv Health Med. 2016 Jan; 5(1):122-5. PMID: 26937324.
    View in: PubMed
  2. Jensen CG, Lansner J, Petersen A, Vangkilde SA, Ringkøbing SP, Frokjaer VG, Adamsen D, Knudsen GM, Denninger JW, Hasselbalch SG. Open and Calm - A randomized controlled trial evaluating a public stress reduction program in Denmark. BMC Public Health. 2015; 15:1245. PMID: 26673225.
    View in: PubMed
  3. Mehta DH, Perez GK, Traeger L, Park ER, Goldman RE, Haime V, Chittenden EH, Denninger JW, Jackson VA. Building Resiliency in a Palliative Care Team: A Pilot Study. J Pain Symptom Manage. 2016 Mar; 51(3):604-8. PMID: 26550936.
    View in: PubMed
  4. Sylvia LG, Bui E, Baier AL, Mehta DH, Denninger JW, Fricchione GL, Casey A, Kagan L, Park ER, Simon NM. Resilient Warrior: A Stress Management Group to Improve Psychological Health in Service Members. Glob Adv Health Med. 2015 Nov; 4(6):38-42. PMID: 26665021.
    View in: PubMed
  5. Stahl JE, Dossett ML, LaJoie AS, Denninger JW, Mehta DH, Goldman R, Fricchione GL, Benson H. Relaxation Response and Resiliency Training and Its Effect on Healthcare Resource Utilization. PLoS One. 2015; 10(10):e0140212. PMID: 26461184; PMCID: PMC4603901.
  6. Kuo B, Bhasin M, Jacquart J, Scult MA, Slipp L, Riklin EI, Lepoutre V, Comosa N, Norton BA, Dassatti A, Rosenblum J, Thurler AH, Surjanhata BC, Hasheminejad NN, Kagan L, Slawsby E, Rao SR, Macklin EA, Fricchione GL, Benson H, Libermann TA, Korzenik J, Denninger JW. Genomic and clinical effects associated with a relaxation response mind-body intervention in patients with irritable bowel syndrome and inflammatory bowel disease. PLoS One. 2015; 10(4):e0123861. PMID: 25927528; PMCID: PMC4415769.
  7. Miller KM, Chad-Friedman E, Haime V, Mehta DH, Lepoutre V, Gilburd D, Peltier-Saxe D, Lilley C, Benson H, Fricchione GL, Denninger JW, Yeung A. The effectiveness of a brief mind-body intervention for treating depression in community health center patients. Glob Adv Health Med. 2015 Mar; 4(2):30-5. PMID: 25984404; PMCID: PMC4424925 [Available on 03/01/16].
  8. Wilson HK, Scult M, Wilcher M, Chudnofsky R, Malloy L, Drewel E, Riklin E, Saul S, Fricchione GL, Benson H, Denninger JW. Teacher-led relaxation response curriculum in an urban high school: impact on student behavioral health and classroom environment. Adv Mind Body Med. 2015; 29(2):6-14. PMID: 25831429.
    View in: PubMed
  9. Scult M, Haime V, Jacquart J, Takahashi J, Moscowitz B, Webster A, Denninger JW, Mehta DH. A healthy aging program for older adults: effects on self-efficacy and morale. Adv Mind Body Med. 2015; 29(1):26-33. PMID: 25607120; PMCID: PMC4437657.
  10. Psaros C, Kagan L, Shifren JL, Willett J, Jacquart J, Alert MD, Macklin EA, Styer AK, Denninger JW, LaRoche KL, Park ER. Mind-body group treatment for women coping with infertility: a pilot study. J Psychosom Obstet Gynaecol. 2015; 36(2):75-83. PMID: 25541217.
    View in: PubMed
  11. Yeung A, Slipp LE, Niles H, Jacquart J, Chow CL, Fava M, Denninger JW, Benson H, Fricchione GL. Effectiveness of the relaxation response-based group intervention for treating depressed chinese american immigrants: a pilot study. Int J Environ Res Public Health. 2014 Sep; 11(9):9186-201. PMID: 25198683; PMCID: PMC4199014.
  12. Heidt T, Sager HB, Courties G, Dutta P, Iwamoto Y, Zaltsman A, von Zur Muhlen C, Bode C, Fricchione GL, Denninger J, Lin CP, Vinegoni C, Libby P, Swirski FK, Weissleder R, Nahrendorf M. Chronic variable stress activates hematopoietic stem cells. Nat Med. 2014 Jul; 20(7):754-8. PMID: 24952646; PMCID: PMC4087061.
  13. Denninger J, Jacquart J, Miller K, Radossi A, Haime V, Macklin E, Gilburd D, Oliver MN, Mehta D, Yeung A, Fricchione G, Benson H. The effectiveness of a community-based mind body group intervention for depression & anxiety: a pilot study. J Altern Complement Med. 2014 May; 20(5):A55. PMID: 24805641.
    View in: PubMed
  14. Mehta D, Chittenden E, Denninger J, Haime V, Traeger L, Jackson V, Park E. Promoting resiliency among palliative care clinicians: a pilot intervention. J Altern Complement Med. 2014 May; 20(5):A102. PMID: 24805386.
    View in: PubMed
  15. Denninger JW, Bhasin M, Huffman J, Niles H, Creager M, Pande R, Liberman T, Fricchione G, Benson H, Zusman R. Clinical and genomic effects of a relaxation response-based mind-body intervention in stage I hypertension. J Altern Complement Med. 2014 May; 20(5):A54. PMID: 24805639.
    View in: PubMed
  16. Vranceanu AM, Gonzalez A, Niles H, Fricchione G, Baim M, Yeung A, Denninger JW, Park ER. Exploring the effectiveness of a modified comprehensive mind-body intervention for medical and psychologic symptom relief. Psychosomatics. 2014 Jul-Aug; 55(4):386-91. PMID: 24751118.
    View in: PubMed
  17. Jacquart J, Miller KM, Radossi A, Haime V, Macklin E, Gilburd D, Nelson Oliver M, Mehta DH, Yeung A, Fricchione GL, Benson H, Denninger JW. The effectiveness of a community-based, mind-body group for symptoms of depression and anxiety. Adv Mind Body Med. 2014; 28(3):6-13. PMID: 25141353.
    View in: PubMed
  18. Niles H, Mehta DH, Corrigan AA, Bhasin MK, Denninger JW. Functional genomics in the study of mind-body therapies. Ochsner J. 2014; 14(4):681-95. PMID: 25598735; PMCID: PMC4295747.
  19. Huffman JC, DuBois CM, Healy BC, Boehm JK, Kashdan TB, Celano CM, Denninger JW, Lyubomirsky S. Feasibility and utility of positive psychology exercises for suicidal inpatients. Gen Hosp Psychiatry. 2014 Jan-Feb; 36(1):88-94. PMID: 24230461.
    View in: PubMed
  20. Alert MD, Rastegar S, Foret M, Slipp L, Jacquart J, Macklin E, Baim M, Fricchione G, Benson H, Denninger J, Yeung A. The effectiveness of a comprehensive mind body weight loss intervention for overweight and obese adults: a pilot study. Complement Ther Med. 2013 Aug; 21(4):286-93. PMID: 23876558.
    View in: PubMed
  21. Bhasin MK, Dusek JA, Chang BH, Joseph MG, Denninger JW, Fricchione GL, Benson H, Libermann TA. Relaxation response induces temporal transcriptome changes in energy metabolism, insulin secretion and inflammatory pathways. PLoS One. 2013; 8(5):e62817. PMID: 23650531; PMCID: PMC3641112.
  22. Yeung A, Slipp LE, Jacquart J, Fava M, Denninger JW, Benson H, Fricchione GL. The treatment of depressed chinese americans using qigong in a health care setting: a pilot study. Evid Based Complement Alternat Med. 2013; 2013:168784. PMID: 23690836; PMCID: PMC3639645.
  23. Park ER, Traeger L, Willett J, Gerade B, Webster A, Rastegar S, Denninger JW, Lee JM. A relaxation response training for women undergoing breast biopsy: exploring integrated care. Breast. 2013 Oct; 22(5):799-805. PMID: 23587450.
    View in: PubMed
  24. Park ER, Traeger L, Vranceanu AM, Scult M, Lerner JA, Benson H, Denninger J, Fricchione GL. The development of a patient-centered program based on the relaxation response: the Relaxation Response Resiliency Program (3RP). Psychosomatics. 2013 Mar-Apr; 54(2):165-74. PMID: 23352048.
    View in: PubMed
  25. Yeung A, Lepoutre V, Wayne P, Yeh G, Slipp LE, Fava M, Denninger JW, Benson H, Fricchione GL. Tai chi treatment for depression in Chinese Americans: a pilot study. Am J Phys Med Rehabil. 2012 Oct; 91(10):863-70. PMID: 22790795.
    View in: PubMed
  26. Bonab AA, Fricchione JG, Gorantla S, Vitalo AG, Auster ME, Levine SJ, Scichilone JM, Hegde M, Foote W, Fricchione GL, Denninger JW, Yarmush DM, Fischman AJ, Yarmush ML, Levine JB. Isolation rearing significantly perturbs brain metabolism in the thalamus and hippocampus. Neuroscience. 2012 Oct 25; 223:457-64. PMID: 22835621.
    View in: PubMed
  27. Vitalo AG, Gorantla S, Fricchione JG, Scichilone JM, Camacho J, Niemi SM, Denninger JW, Benson H, Yarmush ML, Levine JB. Environmental enrichment with nesting material accelerates wound healing in isolation-reared rats. Behav Brain Res. 2012 Jan 15; 226(2):606-12. PMID: 22008380.
    View in: PubMed
  28. Rosenblatt LE, Gorantla S, Torres JA, Yarmush RS, Rao S, Park ER, Denninger JW, Benson H, Fricchione GL, Bernstein B, Levine JB. Relaxation response-based yoga improves functioning in young children with autism: a pilot study. J Altern Complement Med. 2011 Nov; 17(11):1029-35. PMID: 21992466; PMCID: PMC3221508.
  29. Denninger JW, van Nieuwenhuizen AO, Wisniewski SR, Luther JF, Trivedi MH, Rush AJ, Gollan JK, Pizzagalli DA, Fava M. Changes in depressive symptoms and social functioning in the sequenced treatment alternatives to relieve depression study. J Nerv Ment Dis. 2011 Oct; 199(10):807-10. PMID: 21964277.
    View in: PubMed
  30. Huffman JC, Mastromauro CA, Boehm JK, Seabrook R, Fricchione GL, Denninger JW, Lyubomirsky S. Development of a positive psychology intervention for patients with acute cardiovascular disease. Heart Int. 2011 Sep 29; 6(2):e14. PMID: 23825741; PMCID: PMC3699107.
  31. Denninger JW. Commentary on the neurobiology of group psychotherapy: group and the social brain: speeding toward a neurobiological understanding of group psychotherapy. Int J Group Psychother. 2010 Oct; 60(4):595-604. PMID: 21028978.
    View in: PubMed
  32. Iosifescu DV, Greenwald S, Devlin P, Mischoulon D, Denninger JW, Alpert JE, Fava M. Frontal EEG predictors of treatment outcome in major depressive disorder. Eur Neuropsychopharmacol. 2009 Nov; 19(11):772-7. PMID: 19574030.
    View in: PubMed
  33. Matthews JD, Siefert C, Dording C, Denninger JW, Park L, van Nieuwenhuizen AO, Sklarsky K, Hilliker S, Homberger C, Rooney K, Fava M. An open study of aripiprazole and escitalopram for psychotic major depressive disorder. J Clin Psychopharmacol. 2009 Feb; 29(1):73-6. PMID: 19142112.
    View in: PubMed
  34. Iosifescu DV, Greenwald S, Devlin P, Perlis RH, Denninger JW, Alpert JE, Fava M. Pretreatment frontal EEG and changes in suicidal ideation during SSRI treatment in major depressive disorder. Acta Psychiatr Scand. 2008 Apr; 117(4):271-6. PMID: 18307587.
    View in: PubMed
  35. Denninger JW, Papakostas GI, Mahal Y, Merens W, Alpert JE, Nierenberg AA, Yeung A, Fava M. Somatic symptoms in outpatients with major depressive disorder treated with fluoxetine. Psychosomatics. 2006 Jul-Aug; 47(4):348-52. PMID: 16844895.
    View in: PubMed
  36. Papakostas GI, Petersen T, Denninger JW, Tossani E, Pava JA, Alpert JE, Nierenberg AA, Fava M. Psychosocial functioning during the treatment of major depressive disorder with fluoxetine. J Clin Psychopharmacol. 2004 Oct; 24(5):507-11. PMID: 15349006.
    View in: PubMed
  37. Papakostas GI, Petersen T, Denninger JW, Montoya HD, Nierenberg AA, Alpert JE, Fava M. Treatment-related adverse events and outcome in a clinical trial of fluoxetine for major depressive disorder. Ann Clin Psychiatry. 2003 Sep-Dec; 15(3-4):187-92. PMID: 14971864.
    View in: PubMed
  38. Papakostas GI, Petersen T, Denninger J, Sonawalla SB, Mahal Y, Alpert JE, Nierenberg AA, Fava M. Somatic symptoms in treatment-resistant depression. Psychiatry Res. 2003 May 1; 118(1):39-45. PMID: 12759160.
    View in: PubMed
  39. Denninger JW, Schelvis JP, Brandish PE, Zhao Y, Babcock GT, Marletta MA. Interaction of soluble guanylate cyclase with YC-1: kinetic and resonance Raman studies. Biochemistry. 2000 Apr 11; 39(14):4191-8. PMID: 10747811.
    View in: PubMed
  40. Denninger JW, Marletta MA. Guanylate cyclase and the .NO/cGMP signaling pathway. Biochim Biophys Acta. 1999 May 5; 1411(2-3):334-50. PMID: 10320667.
    View in: PubMed
  41. Ernsting BR, Denninger JW, Blumenthal RM, Matthews RG. Regulation of the gltBDF operon of Escherichia coli: how is a leucine-insensitive operon regulated by the leucine-responsive regulatory protein? J Bacteriol. 1993 Nov; 175(22):7160-9. PMID: 7901196; PMCID: PMC206857.
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