Harvard Catalyst Profiles

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Francine Grodstein, Sc.D.

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Overview
My research focuses on healthy aging, particularly in women. My primary research base is the Nurses’ Health Study (NHS). During the past 10 years, I have independently established a study of cognitive function among elderly participants of the Nurses’ Health Study. This has developed into one of the largest existing studies of cognition, with several repeated measures of function in 20,000 women aged 70 years and over. In addition, the success of this project led to funding to incorporate cognitive testing into three large-scale randomized clinical trials of cardiovascular disease prevention (the Women’s Health Study, the Women’s Antioxidant Cardiovascular Study, and Physicians’ Health Study II with a total of 16,000 participants in the cognitive cohort). This work encompasses a large variety of research topics, from identifying lifestyle and dietary factors that influence cognition to exploring biomarkers to predict eventual risk of cognitive impairment. Major publications from this work (in JAMA, New England Journal of Medicine, British Medical Journal) have made substantial contributions to the field.

Numerous trainees have developed their research careers via this cognitive study. Specifically, I am currently mentoring one doctoral student, one postdoctoral fellow, and two junior faculty members in evaluating the effects on cognition of plasma insulin, plasma amyloid beta, plasma IGF, genetic factors, and folate. In addition, one doctoral student who completed her training with me is currently a postdoctoral fellow (at HSPPH) and two postdoctoral fellows who completed their training with me have progressed to junior faculty positions (at the University of Colorado School of Medicine, and at HMS).

I have also initiated a study of risk factors for incontinence in the Nurses’ Health Study. Incontinence is a common problem in older women, with important public health consequences, yet little is known about its epidemiology or prevention. I have designed a self-reported questionnaire to identify urinary incontinence in the NHS participants and have received funding from NIH to conduct this investigation. A postdoctoral fellow and a doctoral student are exploring risk factors for incontinence, such as body mass index, type 2 diabetes , cigarette smoking, and is also examining incidence rates of incontinence, which have not been tracked in any large population-based studies.

Mentoring
Comparison of risk factors for cognitive decline across cancer survivors and women with no cancer history in the Nurses' Health Study
Summer, 06/18/12 - 08/20/12

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AG053273 (KUBZANSKY, LAURA D) Sep 1, 2016 - Mar 31, 2020
    NIH/NIA
    Optimism and Exceptional Longevity
    Role: Principal Investigator
  2. R01DK105050 (GRODSTEIN, FRANCINE) Jun 1, 2016 - May 31, 2019
    NIH/NIDDK
    Urinary Incontinence Epidemiology and Care Seeking
    Role: Principal Investigator
  3. R21MH102570 (KOENEN, KARESTAN C) Sep 2, 2014 - Aug 31, 2016
    NIH/NIMH
    Posttraumatic Stress Disorder and Cognitive Decline in Women
    Role: Principal Investigator
  4. R03CA171817 (GRODSTEIN, FRANCINE) Apr 1, 2013 - Mar 31, 2015
    NIH/NCI
    Systemic cancer treatment and subsequent cognitive decline
    Role: Principal Investigator
  5. R21HD059955 (GRODSTEIN, FRANCINE) Aug 1, 2009 - Jul 31, 2012
    NIH/NICHD
    Long-term Follow-Up of Infertility Patients: A Pilot Study
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Susano MJ, Grasfield RH, Friese M, Rosner B, Crosby G, Bader AM, Kang JD, Smith TR, Lu Y, Groff MW, Chi JH, Grodstein F, Culley DJ. Brief Preoperative Screening for Frailty and Cognitive Impairment Predicts Delirium after Spine Surgery. Anesthesiology. 2020 12 01; 133(6):1184-1191. PMID: 32898243.
    Citations:    Fields:    
  2. Trudel-Fitzgerald C, Zevon ES, Kawachi I, Tucker-Seeley RD, Grodstein F, Kubzansky LD. The Prospective Association of Social Integration With Life Span and Exceptional Longevity in Women. J Gerontol B Psychol Sci Soc Sci. 2020 Nov 13; 75(10):2132-2141. PMID: 31495897.
    Citations:    Fields:    
  3. Yuan C, Fondell E, Ascherio A, Okereke OI, Grodstein F, Hofman A, Willett WC. Long-Term Intake of Dietary Carotenoids Is Positively Associated with Late-Life Subjective Cognitive Function in a Prospective Study in US Women. J Nutr. 2020 07 01; 150(7):1871-1879. PMID: 32386230.
    Citations: 1     Fields:    
  4. Jackson SS, Adami HO, Andreotti G, Beane-Freeman LE, de González AB, Buring JE, Fraser GE, Freedman ND, Gapstur SM, Gierach G, Giles GG, Grodstein F, Hartge P, Jenab M, Kirsh V, Knutsen SF, Lan Q, Larsson SC, Lee IM, Lee MH, Liao LM, Milne RL, Monroe KR, Neuhouser ML, O'Brien KM, Petrick JL, Purdue MP, Rohan TE, Sandin S, Sandler DP, Sawada N, Shadyab AH, Simon TG, Sinha R, Stolzenberg-Solomon R, Tsugane S, Weiderpass E, Wolk A, Yang HI, Zheng W, McGlynn KA, Campbell PT, Koshiol J. Associations between reproductive factors and biliary tract cancers in women from the Biliary Tract Cancers Pooling Project. J Hepatol. 2020 Oct; 73(4):863-872. PMID: 32437829.
    Citations:    Fields:    
  5. Vaughan CP, Markland AD, Huang AJ, Tangpricha V, Grodstein F. Vitamin D Intake and Progression of Urinary Incontinence in Women. Urology. 2020 May 07. PMID: 32387293.
    Citations:    Fields:    
  6. Lane GI, Hagan K, Erekson E, Minassian VA, Grodstein F, Bynum J. Patient-Provider Discussions about Urinary Incontinence among Older Women. J Gerontol A Biol Sci Med Sci. 2020 Apr 30. PMID: 32353111.
    Citations:    Fields:    
  7. Samieri C, Sonawane AR, Lefèvre-Arbogast S, Helmer C, Grodstein F, Glass K. Using network science tools to identify novel diet patterns in prodromal dementia. Neurology. 2020 05 12; 94(19):e2014-e2025. PMID: 32321763.
    Citations:    Fields:    Translation:Humans
  8. Wagner M, Grodstein F, Proust-Lima C, Samieri C. Long-Term Trajectories of Body Weight, Diet, and Physical Activity From Midlife Through Late Life and Subsequent Cognitive Decline in Women. Am J Epidemiol. 2020 04 02; 189(4):305-313. PMID: 31781745.
    Citations: 1     Fields:    Translation:Humans
  9. Schernhammer E, Zhang Y, Strohmaier S, Devore E, Grodstein F. Authors' reply to Erren and colleagues. BMJ. 2020 03 06; 368:m867. PMID: 32144112.
    Citations:    Fields:    Translation:Humans
  10. Kim ES, James P, Zevon ES, Trudel-Fitzgerald C, Kubzansky LD, Grodstein F. Social Media as an Emerging Data Resource for Epidemiologic Research: Characteristics of Regular and Nonregular Social Media Users in Nurses' Health Study II. Am J Epidemiol. 2020 02 28; 189(2):156-161. PMID: 31595957.
    Citations: 2     Fields:    Translation:Humans
  11. Curhan SG, Willett WC, Grodstein F, Curhan GC. Longitudinal study of self-reported hearing loss and subjective cognitive function decline in women. Alzheimers Dement. 2020 04; 16(4):610-620. PMID: 31628050.
    Citations: 1     Fields:    
  12. Kim ES, Tindle HA, Kubzansky LD, Liu S, Duncan MS, Manson JE, Springfield S, Salmoirago-Blotcher E, Shadyab AH, Liu B, Grodstein F, De Vivo I. The Relation of Optimism to Relative Telomere Length in Older Men and Women. Psychosom Med. 2020 Feb/Mar; 82(2):165-171. PMID: 31688458.
    Citations:    Fields:    
  13. Markland AD, Vaughan C, Huang A, Tangpricha V, Grodstein F. Vitamin D intake and the 10-year risk of urgency urinary incontinence in women. J Steroid Biochem Mol Biol. 2020 05; 199:105601. PMID: 32001360.
    Citations:    Fields:    Translation:Humans
  14. Freitas-Simoes TM, Wagner M, Samieri C, Sala-Vila A, Grodstein F. Consumption of Nuts at Midlife and Healthy Aging in Women. J Aging Res. 2020; 2020:5651737. PMID: 32399296.
    Citations:    
  15. Zhang Y, Devore EE, Strohmaier S, Grodstein F, Schernhammer ES. Birth month, birth season, and overall and cardiovascular disease mortality in US women: prospective cohort study. BMJ. 2019 12 18; 367:l6058. PMID: 31852664.
    Citations:    Fields:    Translation:Humans
  16. McGee EE, Jackson SS, Petrick JL, Van Dyke AL, Adami HO, Albanes D, Andreotti G, Beane-Freeman LE, Berrington de Gonzalez A, Buring JE, Chan AT, Chen Y, Fraser GE, Freedman ND, Gao YT, Gapstur SM, Gaziano JM, Giles GG, Grant EJ, Grodstein F, Hartge P, Jenab M, Kitahara CM, Knutsen SF, Koh WP, Larsson SC, Lee IM, Liao LM, Luo J, Milne RL, Monroe KR, Neuhouser ML, O'Brien KM, Peters U, Poynter JN, Purdue MP, Robien K, Sandler DP, Sawada N, Schairer C, Sesso HD, Simon TG, Sinha R, Stolzenberg-Solomon R, Tsugane S, Wang R, Weiderpass E, Weinstein SJ, White E, Wolk A, Yuan JM, Zeleniuch-Jacquotte A, Zhang X, Zhu B, McGlynn KA, Campbell PT, Koshiol J. Smoking, Alcohol, and Biliary Tract Cancer Risk: A Pooling Project of 26 Prospective Studies. J Natl Cancer Inst. 2019 12 01; 111(12):1263-1278. PMID: 31127946.
    Citations: 4     Fields:    Translation:Humans
  17. Penney KL, Townsend MK, Turman C, Glass K, Staller K, Kraft P, Grodstein F, Minassian VA. Genome-Wide Association Study for Urinary and Fecal Incontinence in Women. J Urol. 2020 May; 203(5):978-983. PMID: 31729902.
    Citations:    Fields:    Translation:Humans
  18. Flores-Torres MH, Comerford E, Signorello L, Grodstein F, Lopez-Ridaura R, de Castro F, Familiar I, Ortiz-Panozo E, Lajous M. Impact of adverse childhood experiences on cardiovascular disease risk factors in adulthood among Mexican women. Child Abuse Negl. 2020 01; 99:104175. PMID: 31710961.
    Citations:    Fields:    
  19. Kim IY, Grodstein F, Kraft P, Curhan GC, Hughes KC, Huang H, Kang JH, Hunter DJ. Interaction between apolipoprotein E genotype and hypertension on cognitive function in older women in the Nurses' Health Study. PLoS One. 2019; 14(11):e0224975. PMID: 31697783.
    Citations:    Fields:    Translation:Humans
  20. Clark DW, Okada Y, Moore KHS, Mason D, Pirastu N, Gandin I, Mattsson H, Barnes CLK, Lin K, Zhao JH, Deelen P, Rohde R, Schurmann C, Guo X, Giulianini F, Zhang W, Medina-Gomez C, Karlsson R, Bao Y, Bartz TM, Baumbach C, Biino G, Bixley MJ, Brumat M, Chai JF, Corre T, Cousminer DL, Dekker AM, Eccles DA, van Eijk KR, Fuchsberger C, Gao H, Germain M, Gordon SD, de Haan HG, Harris SE, Hofer E, Huerta-Chagoya A, Igartua C, Jansen IE, Jia Y, Kacprowski T, Karlsson T, Kleber ME, Li SA, Li-Gao R, Mahajan A, Matsuda K, Meidtner K, Meng W, Montasser ME, van der Most PJ, Munz M, Nutile T, Palviainen T, Prasad G, Prasad RB, Priyanka TDS, Rizzi F, Salvi E, Sapkota BR, Shriner D, Skotte L, Smart MC, Smith AV, van der Spek A, Spracklen CN, Strawbridge RJ, Tajuddin SM, Trompet S, Turman C, Verweij N, Viberti C, Wang L, Warren HR, Wootton RE, Yanek LR, Yao J, Yousri NA, Zhao W, Adeyemo AA, Afaq S, Aguilar-Salinas CA, Akiyama M, Albert ML, Allison MA, Alver M, Aung T, Azizi F, Bentley AR, Boeing H, Boerwinkle E, Borja JB, de Borst GJ, Bottinger EP, Broer L, Campbell H, Chanock S, Chee ML, Chen G, Chen YI, Chen Z, Chiu YF, Cocca M, Collins FS, Concas MP, Corley J, Cugliari G, van Dam RM, Damulina A, Daneshpour MS, Day FR, Delgado GE, Dhana K, Doney ASF, Dörr M, Doumatey AP, Dzimiri N, Ebenesersdóttir SS, Elliott J, Elliott P, Ewert R, Felix JF, Fischer K, Freedman BI, Girotto G, Goel A, Gögele M, Goodarzi MO, Graff M, Granot-Hershkovitz E, Grodstein F, Guarrera S, Gudbjartsson DF, Guity K, Gunnarsson B, Guo Y, Hagenaars SP, Haiman CA, Halevy A, Harris TB, Hedayati M, van Heel DA, Hirata M, Höfer I, Hsiung CA, Huang J, Hung YJ, Ikram MA, Jagadeesan A, Jousilahti P, Kamatani Y, Kanai M, Kerrison ND, Kessler T, Khaw KT, Khor CC, de Kleijn DPV, Koh WP, Kolcic I, Kraft P, Krämer BK, Kutalik Z, Kuusisto J, Langenberg C, Launer LJ, Lawlor DA, Lee IT, Lee WJ, Lerch MM, Li L, Liu J, Loh M, London SJ, Loomis S, Lu Y, Luan J, Mägi R, Manichaikul AW, Manunta P, Másson G, Matoba N, Mei XW, Meisinger C, Meitinger T, Mezzavilla M, Milani L, Millwood IY, Momozawa Y, Moore A, Morange PE, Moreno-Macías H, Mori TA, Morrison AC, Muka T, Murakami Y, Murray AD, de Mutsert R, Mychaleckyj JC, Nalls MA, Nauck M, Neville MJ, Nolte IM, Ong KK, Orozco L, Padmanabhan S, Pálsson G, Pankow JS, Pattaro C, Pattie A, Polasek O, Poulter N, Pramstaller PP, Quintana-Murci L, Räikkönen K, Ralhan S, Rao DC, van Rheenen W, Rich SS, Ridker PM, Rietveld CA, Robino A, van Rooij FJA, Ruggiero D, Saba Y, Sabanayagam C, Sabater-Lleal M, Sala CF, Salomaa V, Sandow K, Schmidt H, Scott LJ, Scott WR, Sedaghati-Khayat B, Sennblad B, van Setten J, Sever PJ, Sheu WH, Shi Y, Shrestha S, Shukla SR, Sigurdsson JK, Sikka TT, Singh JR, Smith BH, Stancáková A, Stanton A, Starr JM, Stefansdottir L, Straker L, Sulem P, Sveinbjornsson G, Swertz MA, Taylor AM, Taylor KD, Terzikhan N, Tham YC, Thorleifsson G, Thorsteinsdottir U, Tillander A, Tracy RP, Tusié-Luna T, Tzoulaki I, Vaccargiu S, Vangipurapu J, Veldink JH, Vitart V, Völker U, Vuoksimaa E, Wakil SM, Waldenberger M, Wander GS, Wang YX, Wareham NJ, Wild S, Yajnik CS, Yuan JM, Zeng L, Zhang L, Zhou J, Amin N, Asselbergs FW, Bakker SJL, Becker DM, Lehne B, Bennett DA, van den Berg LH, Berndt SI, Bharadwaj D, Bielak LF, Bochud M, Boehnke M, Bouchard C, Bradfield JP, Brody JA, Campbell A, Carmi S, Caulfield MJ, Cesarini D, Chambers JC, Chandak GR, Cheng CY, Ciullo M, Cornelis M, Cusi D, Smith GD, Deary IJ, Dorajoo R, van Duijn CM, Ellinghaus D, Erdmann J, Eriksson JG, Evangelou E, Evans MK, Faul JD, Feenstra B, Feitosa M, Foisy S, Franke A, Friedlander Y, Gasparini P, Gieger C, Gonzalez C, Goyette P, Grant SFA, Griffiths LR, Groop L, Gudnason V, Gyllensten U, Hakonarson H, Hamsten A, van der Harst P, Heng CK, Hicks AA, Hochner H, Huikuri H, Hunt SC, Jaddoe VWV, De Jager PL, Johannesson M, Johansson Å, Jonas JB, Jukema JW, Junttila J, Kaprio J, Kardia SLR, Karpe F, Kumari M, Laakso M, van der Laan SW, Lahti J, Laudes M, Lea RA, Lieb W, Lumley T, et al. Associations of autozygosity with a broad range of human phenotypes. Nat Commun. 2019 10 31; 10(1):4957. PMID: 31673082.
    Citations: 1     Fields:    Translation:Humans
  21. Lee LO, James P, Zevon ES, Kim ES, Trudel-Fitzgerald C, Spiro A, Grodstein F, Kubzansky LD. Optimism is associated with exceptional longevity in 2 epidemiologic cohorts of men and women. Proc Natl Acad Sci U S A. 2019 09 10; 116(37):18357-18362. PMID: 31451635.
    Citations: 4     Fields:    Translation:Humans
  22. Minassian VA, Hagan KA, Erekson E, Austin AM, Carmichael D, Bynum JPW, Grodstein F. The natural history of urinary incontinence subtypes in the Nurses' Health Studies. Am J Obstet Gynecol. 2020 02; 222(2):163.e1-163.e8. PMID: 31449803.
    Citations: 1     Fields:    Translation:Humans
  23. Kim ES, Fong K, Lee L, Spiro A, Schwartz J, Whitsel E, Horvath S, Wang C, Hou L, Baccarelli AA, Li Y, Stewart J, Manson JE, Grodstein F, DeMeo DL, Kubzansky LD. Optimism is not associated with two indicators of DNA methylation aging. Aging (Albany NY). 2019 07 18; 11(14):4970-4989. PMID: 31322503.
    Citations: 1     Fields:    Translation:HumansCells
  24. Shi S, Afilalo J, Lipsitz LA, Popma JJ, Khabbaz KR, Laham RJ, Guibone K, Grodstein F, Lux E, Kim DH. Frailty Phenotype and Deficit Accumulation Frailty Index in Predicting Recovery After Transcatheter and Surgical Aortic Valve Replacement. J Gerontol A Biol Sci Med Sci. 2019 07 12; 74(8):1249-1256. PMID: 30165422.
    Citations: 3     Fields:    Translation:Humans
  25. Bynum J, Passow H, Austin A, Carmichael D, Grodstein F. Serious Illness and End-of-Life Treatments for Nurses Compared with the General Population. J Am Geriatr Soc. 2019 08; 67(8):1582-1589. PMID: 31287929.
    Citations: 1     Fields:    Translation:Humans
  26. Erekson E, Hagan KA, Austin A, Carmichael D, Minassian VA, Grodstein F, Bynum JPW. Outpatient Evaluation and Management Visits for Urinary Incontinence in Older Women. J Urol. 2019 08; 202(2):333-338. PMID: 30865568.
    Citations:    Fields:    Translation:Humans
  27. Trudel-Fitzgerald C, James P, Kim ES, Zevon ES, Grodstein F, Kubzansky LD. Prospective associations of happiness and optimism with lifestyle over up to two decades. Prev Med. 2019 09; 126:105754. PMID: 31220509.
    Citations: 3     Fields:    Translation:Humans
  28. Kim ES, James P, Zevon ES, Trudel-Fitzgerald C, Kubzansky LD, Grodstein F. Optimism and Healthy Aging in Women and Men. Am J Epidemiol. 2019 06 01; 188(6):1084-1091. PMID: 30834429.
    Citations: 1     Fields:    Translation:Humans
  29. Jackson SS, Van Dyke AL, Zhu B, Pfeiffer RM, Petrick JL, Adami HO, Albanes D, Andreotti G, Beane Freeman LE, Berrington de González A, Buring JE, Chan AT, Chen Y, Fraser GE, Freedman ND, Gao YT, Gapstur SM, Gaziano JM, Giles GG, Grant EJ, Grodstein F, Hartge P, Jenab M, Kitahara CM, Knutsen SF, Koh WP, Larsson SC, Lee IM, Liao LM, Luo J, McGee EE, Milne RL, Monroe KR, Neuhouser ML, O'Brien KM, Peters U, Poynter JN, Purdue MP, Robien K, Sandler DP, Sawada N, Schairer C, Sesso HD, Simon TG, Sinha R, Stolzenberg-Solomon RZ, Tsugane S, Wang R, Weiderpass E, Weinstein SJ, White E, Wolk A, Yuan JM, Zeleniuch-Jacquotte A, Zhang X, McGlynn KA, Campbell PT, Koshiol J. Anthropometric Risk Factors for Cancers of the Biliary Tract in the Biliary Tract Cancers Pooling Project. Cancer Res. 2019 08 01; 79(15):3973-3982. PMID: 31113819.
    Citations: 1     Fields:    Translation:Humans
  30. Kim DH, Afilalo J, Shi SM, Popma JJ, Khabbaz KR, Laham RJ, Grodstein F, Guibone K, Lux E, Lipsitz LA. Evaluation of Changes in Functional Status in the Year After Aortic Valve Replacement. JAMA Intern Med. 2019 03 01; 179(3):383-391. PMID: 30715097.
    Citations: 6     Fields:    Translation:Humans
  31. Devore E, Hall KE, Schernhammer ES, Grodstein F. CE: Original Research: Midlife Hypertension and Hypercholesterolemia in Relation to Cognitive Function Later in Life in Black Women. Am J Nurs. 2019 02; 119(2):22-30. PMID: 30640207.
    Citations:    Fields:    Translation:Humans
  32. Curhan SG, Willett WC, Grodstein F, Curhan GC. Longitudinal study of hearing loss and subjective cognitive function decline in men. Alzheimers Dement. 2019 04; 15(4):525-533. PMID: 30709794.
    Citations: 2     Fields:    Translation:Humans
  33. Austin AM, Kapadia NS, Brooks GA, Onega TL, Eliassen AH, Tamimi RM, Holmes M, Wang Q, Grodstein F, Tosteson ANA. Comparison of treatment of early-stage breast cancer among Nurses' Health Study participants and other Medicare beneficiaries. Breast Cancer Res Treat. 2019 Apr; 174(3):759-767. PMID: 30607634.
    Citations:    Fields:    Translation:Humans
  34. Hagan KA, Grodstein F. The Alternative Healthy Eating Index and Physical Function Impairment in Men. J Nutr Health Aging. 2019; 23(5):459-465. PMID: 31021363.
    Citations:    Fields:    Translation:Humans
  35. James P, Kim ES, Kubzansky LD, Zevon ES, Trudel-Fitzgerald C, Grodstein F. Optimism and Healthy Aging in Women. Am J Prev Med. 2019 01; 56(1):116-124. PMID: 30573140.
    Citations: 3     Fields:    Translation:Humans
  36. Bhupathiraju SN, Grodstein F, Stampfer MJ, Willett WC, Crandall CJ, Shifren JL, Manson JE. Vaginal estrogen use and chronic disease risk in the Nurses' Health Study. Menopause. 2018 12 17; 26(6):603-610. PMID: 30562320.
    Citations:    Fields:    Translation:Humans
  37. Kang JH, Bynum JPW, Zhang L, Grodstein F, Stevenson DG. Predictors of Advance Care Planning in Older Women: The Nurses' Health Study. J Am Geriatr Soc. 2019 02; 67(2):292-301. PMID: 30537051.
    Citations:    Fields:    Translation:Humans
  38. Bronson MR, Kapadia NS, Austin AM, Wang Q, Feskanich D, Bynum JPW, Grodstein F, Tosteson ANA. Leveraging Linkage of Cohort Studies With Administrative Claims Data to Identify Individuals With Cancer. Med Care. 2018 12; 56(12):e83-e89. PMID: 29334524.
    Citations: 1     Fields:    Translation:Humans
  39. Yuan C, Fondell E, Bhushan A, Ascherio A, Okereke OI, Grodstein F, Willett WC. Long-term intake of vegetables and fruits and subjective cognitive function in US men. Neurology. 2019 01 01; 92(1):e63-e75. PMID: 30464030.
    Citations: 3     Fields:    Translation:HumansAnimals
  40. Hagan KA, Harrington LB, Kim J, Lindström S, Camargo CA, Grodstein F, Kabrhel C. Adiposity throughout the life course and risk of venous thromboembolism. Thromb Res. 2018 12; 172:67-73. PMID: 30384037.
    Citations: 1     Fields:    Translation:Humans
  41. Staller K, Song M, Grodstein F, Matthews CA, Whitehead WE, Kuo B, Chan AT, Townsend MK. Physical Activity, BMI, and Risk of Fecal Incontinence in the Nurses' Health Study. Clin Transl Gastroenterol. 2018 10 25; 9(10):200. PMID: 30356052.
    Citations: 1     Fields:    Translation:Humans
  42. Butt J, Varga MG, Blot WJ, Teras L, Visvanathan K, Le Marchand L, Haiman C, Chen Y, Bao Y, Sesso HD, Wassertheil-Smoller S, Ho GYF, Tinker LE, Peek RM, Potter JD, Cover TL, Hendrix LH, Huang LC, Hyslop T, Um C, Grodstein F, Song M, Zeleniuch-Jacquotte A, Berndt S, Hildesheim A, Waterboer T, Pawlita M, Epplein M. Serologic Response to Helicobacter pylori Proteins Associated With Risk of Colorectal Cancer Among Diverse Populations in the United States. Gastroenterology. 2019 01; 156(1):175-186.e2. PMID: 30296434.
    Citations: 7     Fields:    Translation:HumansCells
  43. Kapadia NS, Austin AM, Carmichael DQ, Wang Q, Erekson ED, Feskanich D, Grodstein F, Tosteson ANA, Bynum JPW. Medicare Utilization and Spending Among Nurses Compared with the General United States Population. J Womens Health (Larchmt). 2018 12; 27(12):1466-1473. PMID: 30118370.
    Citations: 2     Fields:    Translation:Humans
  44. Staller K, Song M, Grodstein F, Whitehead WE, Matthews CA, Kuo B, Chan AT. Increased Long-term Dietary Fiber Intake Is Associated With a Decreased Risk of Fecal Incontinence in Older Women. Gastroenterology. 2018 09; 155(3):661-667.e1. PMID: 29758215.
    Citations:    Fields:    Translation:Humans
  45. Hagan KA, Harrington LB, Kim J, Zeleznik O, Rimm EB, Grodstein F, Kabrhel C. Reduction in physical function in women after venous thromboembolism. J Thromb Haemost. 2018 Jun 08. PMID: 29883039.
    Citations: 3     Fields:    
  46. Lindström S, Germain M, Crous-Bou M, Smith EN, Morange PE, van Hylckama Vlieg A, de Haan HG, Chasman D, Ridker P, Brody J, de Andrade M, Heit JA, Tang W, De Vivo I, Grodstein F, Smith NL, Tregouet D, Kabrhel C. Correction to: Assessing the causal relationship between obesity and venous thromboembolism through a Mendelian Randomization study. Hum Genet. 2018 05; 137(5):429. PMID: 29779052.
    Citations:    Fields:    
  47. Samieri C, Morris MC, Bennett DA, Berr C, Amouyel P, Dartigues JF, Tzourio C, Chasman DI, Grodstein F. Fish Intake, Genetic Predisposition to Alzheimer Disease, and Decline in Global Cognition and Memory in 5 Cohorts of Older Persons. Am J Epidemiol. 2018 05 01; 187(5):933-940. PMID: 29053784.
    Citations: 6     Fields:    Translation:HumansAnimals
  48. Benetou V, Orfanos P, Feskanich D, Michaëlsson K, Pettersson-Kymmer U, Byberg L, Eriksson S, Grodstein F, Wolk A, Jankovic N, de Groot LCPGM, Boffetta P, Trichopoulou A. Mediterranean diet and hip fracture incidence among older adults: the CHANCES project. Osteoporos Int. 2018 Jul; 29(7):1591-1599. PMID: 29656347.
    Citations: 5     Fields:    Translation:Humans
  49. Hagan KA, Erekson E, Austin A, Minassian VA, Townsend MK, Bynum JPW, Grodstein F. A prospective study of the natural history of urinary incontinence in women. Am J Obstet Gynecol. 2018 05; 218(5):502.e1-502.e8. PMID: 29425839.
    Citations: 2     Fields:    Translation:Humans
  50. Li S, Hagan K, Grodstein F, VanderWeele TJ. Social integration and healthy aging among U.S. women. Prev Med Rep. 2018 Mar; 9:144-148. PMID: 29527467.
    Citations:    
  51. Van Dyke AL, Langhamer MS, Zhu B, Pfeiffer RM, Albanes D, Andreotti G, Beane Freeman LE, Chan AT, Freedman ND, Gapstur SM, Giles GG, Grodstein F, Liao LM, Luo J, Milne RL, Monroe KR, Neuhouser ML, Poynter JN, Purdue MP, Robien K, Schairer C, Sinha R, Weinstein S, Zhang X, Petrick JL, McGlynn KA, Campbell PT, Koshiol J. Family History of Cancer and Risk of Biliary Tract Cancers: Results from the Biliary Tract Cancers Pooling Project. Cancer Epidemiol Biomarkers Prev. 2018 03; 27(3):348-351. PMID: 29339358.
    Citations: 2     Fields:    Translation:Humans
  52. Berendsen AM, Kang JH, Feskens EJM, de Groot CPGM, Grodstein F, van de Rest O. Association of Long-Term Adherence to the MIND Diet with Cognitive Function and Cognitive Decline in American Women. J Nutr Health Aging. 2018; 22(2):222-229. PMID: 29380849.
    Citations: 5     Fields:    Translation:Humans
  53. Bhushan A, Fondell E, Ascherio A, Yuan C, Grodstein F, Willett W. Adherence to Mediterranean diet and subjective cognitive function in men. Eur J Epidemiol. 2018 02; 33(2):223-234. PMID: 29147948.
    Citations: 10     Fields:    Translation:Humans
  54. Fondell E, Townsend MK, Unger LD, Okereke OI, Grodstein F, Ascherio A, Willett WC. Physical activity across adulthood and subjective cognitive function in older men. Eur J Epidemiol. 2018 01; 33(1):79-87. PMID: 29147949.
    Citations: 3     Fields:    Translation:Humans
  55. Bhupathiraju SN, Grodstein F, Rosner BA, Stampfer MJ, Hu FB, Willett WC, Manson JE. Hormone Therapy Use and Risk of Chronic Disease in the Nurses' Health Study: A Comparative Analysis With the Women's Health Initiative. Am J Epidemiol. 2017 Sep 15; 186(6):696-708. PMID: 28938710.
    Citations: 3     Fields:    Translation:Humans
  56. Lochhead P, Hagan K, Joshi AD, Khalili H, Nguyen LH, Grodstein F, Chan AT. Association Between Proton Pump Inhibitor Use and Cognitive Function in Women. Gastroenterology. 2017 10; 153(4):971-979.e4. PMID: 28728964.
    Citations: 6     Fields:    Translation:Humans
  57. Zheng Y, Manson JE, Yuan C, Liang MH, Grodstein F, Stampfer MJ, Willett WC, Hu FB. Associations of Weight Gain From Early to Middle Adulthood With Major Health Outcomes Later in Life. JAMA. 2017 Jul 18; 318(3):255-269. PMID: 28719691.
    Citations: 59     Fields:    Translation:Humans
  58. Lindström S, Germain M, Crous-Bou M, Smith EN, Morange PE, van Hylckama Vlieg A, de Haan HG, Chasman D, Ridker P, Brody J, de Andrade M, Heit JA, Tang W, DeVivo I, Grodstein F, Smith NL, Tregouet D, Kabrhel C. Assessing the causal relationship between obesity and venous thromboembolism through a Mendelian Randomization study. Hum Genet. 2017 07; 136(7):897-902. PMID: 28528403.
    Citations: 5     Fields:    Translation:Humans
  59. Papadimitriou N, Tsilidis KK, Orfanos P, Benetou V, Ntzani EE, Soerjomataram I, Künn-Nelen A, Pettersson-Kymmer U, Eriksson S, Brenner H, Schöttker B, Saum KU, Holleczek B, Grodstein FD, Feskanich D, Orsini N, Wolk A, Bellavia A, Wilsgaard T, Jørgensen L, Boffetta P, Trichopoulos D, Trichopoulou A. Burden of hip fracture using disability-adjusted life-years: a pooled analysis of prospective cohorts in the CHANCES consortium. Lancet Public Health. 2017 05; 2(5):e239-e246. PMID: 29253489.
    Citations: 22     Fields:    Translation:Humans
  60. Berendsen AA, Kang JH, van de Rest O, Jankovic N, Kampman E, Kiefte-de Jong JC, Franco OH, Ikram MA, Pikhart H, Nilsson LM, Brenner H, Boffetta P, Rafnsson SB, Gustafson D, Kyrozis A, Trichopoulou A, Feskens EJ, Grodstein F, de Groot LC. Association of Adherence to a Healthy Diet with Cognitive Decline in European and American Older Adults: A Meta-Analysis within the CHANCES Consortium. Dement Geriatr Cogn Disord. 2017; 43(3-4):215-227. PMID: 28324877.
    Citations: 1     Fields:    Translation:Humans
  61. Stampfer M, Grodstein F, Willett W, Eliassen H. Stampfer et al. Respond. Am J Public Health. 2017 03; 107(3):e3. PMID: 28177811.
    Citations:    Fields:    Translation:HumansPHPublic Health
  62. Staller K, Townsend MK, Khalili H, Mehta R, Grodstein F, Whitehead WE, Matthews CA, Kuo B, Chan AT. Menopausal Hormone Therapy Is Associated With Increased Risk of Fecal Incontinence in Women After Menopause. Gastroenterology. 2017 06; 152(8):1915-1921.e1. PMID: 28209529.
    Citations: 4     Fields:    Translation:Humans
  63. Bender AC, Austin AM, Grodstein F, Bynum JPW. Executive function, episodic memory, and Medicare expenditures. Alzheimers Dement. 2017 Jul; 13(7):792-800. PMID: 28174070.
    Citations: 3     Fields:    Translation:Humans
  64. Katsoulis M, Benetou V, Karapetyan T, Feskanich D, Grodstein F, Pettersson-Kymmer U, Eriksson S, Wilsgaard T, Jørgensen L, Ahmed LA, Schöttker B, Brenner H, Bellavia A, Wolk A, Kubinova R, Stegeman B, Bobak M, Boffetta P, Trichopoulou A. Excess mortality after hip fracture in elderly persons from Europe and the USA: the CHANCES project. J Intern Med. 2017 03; 281(3):300-310. PMID: 28093824.
    Citations: 20     Fields:    Translation:Humans
  65. Berendsen AAM, Kang JH, van de Rest O, Feskens EJM, de Groot LCPGM, Grodstein F. The Dietary Approaches to Stop Hypertension Diet, Cognitive Function, and Cognitive Decline in American Older Women. J Am Med Dir Assoc. 2017 May 01; 18(5):427-432. PMID: 28108204.
    Citations: 13     Fields:    Translation:Humans
  66. Sumner JA, Hagan K, Grodstein F, Roberts AL, Harel B, Koenen KC. Posttraumatic stress disorder symptoms and cognitive function in a large cohort of middle-aged women. Depress Anxiety. 2017 04; 34(4):356-366. PMID: 28072503.
    Citations: 8     Fields:    Translation:Humans
  67. Kim ES, Hagan KA, Grodstein F, DeMeo DL, De Vivo I, Kubzansky LD. Optimism and Cause-Specific Mortality: A Prospective Cohort Study. Am J Epidemiol. 2017 01 01; 185(1):21-29. PMID: 27927621.
    Citations: 21     Fields:    Translation:Humans
  68. Gillis JC, Chang SC, Devore EE, Rosner BA, Grodstein F, Okereke OI. Patterns of late-life depressive symptoms and subsequent declines in cognitive domains. Int J Geriatr Psychiatry. 2017 12; 32(12):1330-1341. PMID: 29193360.
    Citations:    Fields:    Translation:Humans
  69. Wu S, Cho E, Li W, Grodstein F, Qureshi AA. Hormonal Factors and Risk of Psoriasis in Women: A Cohort Study. Acta Derm Venereol. 2016 Nov 02; 96(7):927-931. PMID: 26658522.
    Citations: 2     Fields:    Translation:Humans
  70. Sajeev G, Weuve J, Jackson JW, VanderWeele TJ, Bennett DA, Grodstein F, Blacker D. Late-life Cognitive Activity and Dementia: A Systematic Review and Bias Analysis. Epidemiology. 2016 09; 27(5):732-42. PMID: 27227783.
    Citations: 6     Fields:    Translation:Humans
  71. Hagan KA, Munger KL, Ascherio A, Grodstein F. Epidemiology of Major Neurodegenerative Diseases in Women: Contribution of the Nurses' Health Study. Am J Public Health. 2016 Sep; 106(9):1650-5. PMID: 27459462.
    Citations: 3     Fields:    Translation:Humans
  72. Bhupathiraju SN, Grodstein F, Stampfer MJ, Willett WC, Hu FB, Manson JE. Exogenous Hormone Use: Oral Contraceptives, Postmenopausal Hormone Therapy, and Health Outcomes in the Nurses' Health Study. Am J Public Health. 2016 Sep; 106(9):1631-7. PMID: 27459451.
    Citations: 8     Fields:    Translation:Humans
  73. Crous-Bou M, De Vivo I, Camargo CA, Varraso R, Grodstein F, Jensen MK, Kraft P, Goldhaber SZ, Lindström S, Kabrhel C. Interactions of established risk factors and a GWAS-based genetic risk score on the risk of venous thromboembolism. Thromb Haemost. 2016 Sep 27; 116(4):705-13. PMID: 27305932.
    Citations: 2     Fields:    Translation:Humans
  74. Benetou V, Orfanos P, Feskanich D, Michaëlsson K, Pettersson-Kymmer U, Eriksson S, Grodstein F, Wolk A, Bellavia A, Ahmed LA, Boffeta P, Trichopoulou A. Fruit and Vegetable Intake and Hip Fracture Incidence in Older Men and Women: The CHANCES Project. J Bone Miner Res. 2016 09; 31(9):1743-52. PMID: 27061845.
    Citations: 15     Fields:    Translation:HumansAnimals
  75. Hagan KA, Chiuve SE, Stampfer MJ, Katz JN, Grodstein F. Greater Adherence to the Alternative Healthy Eating Index Is Associated with Lower Incidence of Physical Function Impairment in the Nurses' Health Study. J Nutr. 2016 07; 146(7):1341-7. PMID: 27170727.
    Citations: 10     Fields:    Translation:Humans
  76. Koyama AK, Tworoger SS, Eliassen AH, Okereke OI, Weisskopf MG, Rosner B, Yaffe K, Grodstein F. Endogenous sex hormones and cognitive function in older women. Alzheimers Dement. 2016 07; 12(7):758-65. PMID: 26806389.
    Citations: 5     Fields:    Translation:Humans
  77. Farland LV, Collier AY, Correia KF, Grodstein F, Chavarro JE, Rich-Edwards J, Missmer SA. Who receives a medical evaluation for infertility in the United States? Fertil Steril. 2016 05; 105(5):1274-1280. PMID: 26785253.
    Citations: 6     Fields:    Translation:Humans
  78. Devore EE, Grodstein F, Schernhammer ES. Sleep Duration in Relation to Cognitive Function among Older Adults: A Systematic Review of Observational Studies. Neuroepidemiology. 2016; 46(1):57-78. PMID: 26735553.
    Citations: 8     Fields:    Translation:Humans
  79. Vercambre MN, Okereke OI, Kawachi I, Grodstein F, Kang JH. Self-Reported Change in Quality of Life with Retirement and Later Cognitive Decline: Prospective Data from the Nurses' Health Study. J Alzheimers Dis. 2016; 52(3):887-98. PMID: 27060944.
    Citations: 3     Fields:    Translation:Humans
  80. Koyama AK, Hagan KA, Okereke OI, Weisskopf MG, Rosner B, Grodstein F. Evaluation of a Self-Administered Computerized Cognitive Battery in an Older Population. Neuroepidemiology. 2015; 45(4):264-72. PMID: 26501919.
    Citations: 3     Fields:    Translation:Humans
  81. Kim DH, Grodstein F, Newman AB, Chaves PH, Odden MC, Klein R, Sarnak MJ, Lipsitz LA. Microvascular and Macrovascular Abnormalities and Cognitive and Physical Function in Older Adults: Cardiovascular Health Study. J Am Geriatr Soc. 2015 Sep; 63(9):1886-93. PMID: 26338279.
    Citations: 7     Fields:    Translation:Humans
  82. Chew EY, Clemons TE, Agrón E, Launer LJ, Grodstein F, Bernstein PS. Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial. JAMA. 2015 Aug 25; 314(8):791-801. PMID: 26305649.
    Citations: 33     Fields:    Translation:Humans
  83. Joshi PK, Esko T, Mattsson H, Eklund N, Gandin I, Nutile T, Jackson AU, Schurmann C, Smith AV, Zhang W, Okada Y, Stancáková A, Faul JD, Zhao W, Bartz TM, Concas MP, Franceschini N, Enroth S, Vitart V, Trompet S, Guo X, Chasman DI, O'Connel JR, Corre T, Nongmaithem SS, Chen Y, Mangino M, Ruggiero D, Traglia M, Farmaki AE, Kacprowski T, Bjonnes A, van der Spek A, Wu Y, Giri AK, Yanek LR, Wang L, Hofer E, Rietveld CA, McLeod O, Cornelis MC, Pattaro C, Verweij N, Baumbach C, Abdellaoui A, Warren HR, Vuckovic D, Mei H, Bouchard C, Perry JRB, Cappellani S, Mirza SS, Benton MC, Broeckel U, Medland SE, Lind PA, Malerba G, Drong A, Yengo L, Bielak LF, Zhi D, van der Most PJ, Shriner D, Mägi R, Hemani G, Karaderi T, Wang Z, Liu T, Demuth I, Zhao JH, Meng W, Lataniotis L, van der Laan SW, Bradfield JP, Wood AR, Bonnefond A, Ahluwalia TS, Hall LM, Salvi E, Yazar S, Carstensen L, de Haan HG, Abney M, Afzal U, Allison MA, Amin N, Asselbergs FW, Bakker SJL, Barr RG, Baumeister SE, Benjamin DJ, Bergmann S, Boerwinkle E, Bottinger EP, Campbell A, Chakravarti A, Chan Y, Chanock SJ, Chen C, Chen YI, Collins FS, Connell J, Correa A, Cupples LA, Smith GD, Davies G, Dörr M, Ehret G, Ellis SB, Feenstra B, Feitosa MF, Ford I, Fox CS, Frayling TM, Friedrich N, Geller F, Scotland G, Gillham-Nasenya I, Gottesman O, Graff M, Grodstein F, Gu C, Haley C, Hammond CJ, Harris SE, Harris TB, Hastie ND, Heard-Costa NL, Heikkilä K, Hocking LJ, Homuth G, Hottenga JJ, Huang J, Huffman JE, Hysi PG, Ikram MA, Ingelsson E, Joensuu A, Johansson Å, Jousilahti P, Jukema JW, Kähönen M, Kamatani Y, Kanoni S, Kerr SM, Khan NM, Koellinger P, Koistinen HA, Kooner MK, Kubo M, Kuusisto J, Lahti J, Launer LJ, Lea RA, Lehne B, Lehtimäki T, Liewald DCM, Lind L, Loh M, Lokki ML, London SJ, Loomis SJ, Loukola A, Lu Y, Lumley T, Lundqvist A, Männistö S, Marques-Vidal P, Masciullo C, Matchan A, Mathias RA, Matsuda K, Meigs JB, Meisinger C, Meitinger T, Menni C, Mentch FD, Mihailov E, Milani L, Montasser ME, Montgomery GW, Morrison A, Myers RH, Nadukuru R, Navarro P, Nelis M, Nieminen MS, Nolte IM, O'Connor GT, Ogunniyi A, Padmanabhan S, Palmas WR, Pankow JS, Patarcic I, Pavani F, Peyser PA, Pietilainen K, Poulter N, Prokopenko I, Ralhan S, Redmond P, Rich SS, Rissanen H, Robino A, Rose LM, Rose R, Sala C, Salako B, Salomaa V, Sarin AP, Saxena R, Schmidt H, Scott LJ, Scott WR, Sennblad B, Seshadri S, Sever P, Shrestha S, Smith BH, Smith JA, Soranzo N, Sotoodehnia N, Southam L, Stanton AV, Stathopoulou MG, Strauch K, Strawbridge RJ, Suderman MJ, Tandon N, Tang ST, Taylor KD, Tayo BO, Töglhofer AM, Tomaszewski M, Tšernikova N, Tuomilehto J, Uitterlinden AG, Vaidya D, van Hylckama Vlieg A, van Setten J, Vasankari T, Vedantam S, Vlachopoulou E, Vozzi D, Vuoksimaa E, Waldenberger M, Ware EB, Wentworth-Shields W, Whitfield JB, Wild S, Willemsen G, Yajnik CS, Yao J, Zaza G, Zhu X, Project TBJ, Salem RM, Melbye M, Bisgaard H, Samani NJ, Cusi D, Mackey DA, Cooper RS, Froguel P, Pasterkamp G, Grant SFA, Hakonarson H, Ferrucci L, Scott RA, Morris AD, Palmer CNA, Dedoussis G, Deloukas P, Bertram L, Lindenberger U, Berndt SI, Lindgren CM, Timpson NJ, Tönjes A, Munroe PB, Sørensen TIA, Rotimi CN, Arnett DK, Oldehinkel AJ, Kardia SLR, Balkau B, Gambaro G, Morris AP, Eriksson JG, Wright MJ, Martin NG, Hunt SC, Starr JM, Deary IJ, Griffiths LR, Tiemeier H, Pirastu N, Kaprio J, Wareham NJ, Pérusse L, Wilson JG, Girotto G, Caulfield MJ, Raitakari O, Boomsma DI, Gieger C, van der Harst P, Hicks AA, Kraft P, Sinisalo J, Knekt P, Johannesson M, Magnusson PKE, Hamsten A, Schmidt R, Borecki IB, Vartiainen E, Becker DM, Bharadwaj D, Mohlke KL, Boehnke M, van Duijn CM, Sanghera DK, Teumer A, Zeggini E, Metspalu A, Gasparini P, Ulivi S, Ober C, Toniolo D, Rudan I, Porteous DJ, Ciullo M, Spector TD, Hayward C, Dupuis J, Loos RJF, Wright AF, Chandak GR, Vollenweider P, Shuldiner A, Ridker PM, Rotter JI, Sattar N, Gyllensten U, North KE, Pirastu M, Psaty BM, Weir DR, Laakso M, Gudnason V, Takahashi A, et al. Directional dominance on stature and cognition in diverse human populations. Nature. 2015 Jul 23; 523(7561):459-462. PMID: 26131930.
    Citations: 52     Fields:    Translation:Humans
  84. Farland LV, Grodstein F, Srouji SS, Forman JP, Rich-Edwards J, Chavarro JE, Missmer SA. Infertility, fertility treatment, and risk of hypertension. Fertil Steril. 2015 Aug; 104(2):391-7. PMID: 26049054.
    Citations: 6     Fields:    Translation:Humans
  85. Ibrahim-Verbaas CA, Bressler J, Debette S, Schuur M, Smith AV, Bis JC, Davies G, Trompet S, Smith JA, Wolf C, Chibnik LB, Liu Y, Vitart V, Kirin M, Petrovic K, Polasek O, Zgaga L, Fawns-Ritchie C, Hoffmann P, Karjalainen J, Lahti J, Llewellyn DJ, Schmidt CO, Mather KA, Chouraki V, Sun Q, Resnick SM, Rose LM, Oldmeadow C, Stewart M, Smith BH, Gudnason V, Yang Q, Mirza SS, Jukema JW, deJager PL, Harris TB, Liewald DC, Amin N, Coker LH, Stegle O, Lopez OL, Schmidt R, Teumer A, Ford I, Karbalai N, Becker JT, Jonsdottir MK, Au R, Fehrmann R, H