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David H. Sachs, M.D.

TitlePaul S. Russell/Warner Lambert Professor of Surgery
InstitutionMassachusetts General Hospital
DepartmentSurgery
AddressMassachusetts General Hospital
149-9019 Transplantation Bio Rsrch Ctr
149 13th Street
Charlestown MA 02129
Phone617/726-4065
Fax617/726-4067
vCardDownload vCard (login for email)

 Mentoring 
 completed student projects
HHMI
Full Time/Year Long, 07/01/98 - 06/30/99
Vascularized Thymic Transplantation as a Strategy for Tolerance Induction
Summer, 06/18/00 - 08/31/00
Vascularized Thymic Transplantation as a Strategy for Tolerance Induction
Part Time/Continuation, 01/03/01 - 03/15/01

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Yamada Y, Ochiai T, Boskovic S, Nadazdin O, Oura T, Schoenfeld D, Cappetta K, Smith RN, Colvin RB, Madsen JC, Sachs DH, Benichou G, Cosimi AB, Kawai T. Use of CTLA4Ig for Induction of Mixed Chimerism and Renal Allograft Tolerance in Nonhuman Primates. Am J Transplant. 2014 Dec; 14(12):2704-12.
    View in: PubMed
  2. Tena A, Kurtz J, Leonard DA, Dobrinsky JR, Terlouw SL, Mtango N, Verstegen J, Germana S, Mallard C, Arn JS, Sachs DH, Hawley RJ. Transgenic Expression of Human CD47 Markedly Increases Engraftment in a Murine Model of Pig-to-Human Hematopoietic Cell Transplantation. Am J Transplant. 2014 Dec; 14(12):2713-22.
    View in: PubMed
  3. Scalea JR, Torabi R, Tena A, Tasaki M, Gillon BC, Moran S, Cormack T, Villani V, Shimizu A, Sachs DH, Yamada K. The rejuvenating effects of leuprolide acetate on the aged baboon's thymus. Transpl Immunol. 2014 Sep; 31(3):134-9.
    View in: PubMed
  4. Scalea JR, Villani V, Gillon BC, Weiner J, Gianello P, Turcotte N, Arn JS, Yamada K, Sachs DH. Development of antidonor antibody directed toward non-major histocompatibility complex antigens in tolerant animals. Transplantation. 2014 Sep 15; 98(5):514-9.
    View in: PubMed
  5. Wei M, Marino J, Trowell A, Zhang H, Stromp Peraino J, Rajasekera PV, Madsen JC, Sachs DH, Huang CA, Benichou G, Wang Z. Diphtheria toxin-based recombinant murine IL-2 fusion toxin for depleting murine regulatory T cells in vivo. Protein Eng Des Sel. 2014 Sep; 27(9):289-95.
    View in: PubMed
  6. Mathes DW, Solari MG, Gazelle GS, Butler PE, Wu A, Nazzal A, Nielsen GP, Huang CA, Sachs DH, Lee WP, Randolph MA. Stable mixed hematopoietic chimerism permits tolerance of vascularized composite allografts across a full major histocompatibility mismatch in swine. Transpl Int. 2014 Oct; 27(10):1086-96.
    View in: PubMed
  7. Yamada K, Tasaki M, Sekijima M, Wilkinson RA, Villani V, Moran SG, Cormack TA, Hanekamp IM, Arn JS, Fishman JA, Shimizu A, Sachs DH. Porcine cytomegalovirus infection is associated with early rejection of kidney grafts in a pig to baboon xenotransplantation model. Transplantation. 2014 Aug 27; 98(4):411-8.
    View in: PubMed
  8. Bichoupan K, Martel-Laferriere V, Sachs D, Ng M, Schonfeld EA, Pappas A, Crismale J, Stivala A, Khaitova V, Gardenier D, Linderman M, Perumalswami PV, Schiano TD, Odin JA, Liu L, Moskowitz AJ, Dieterich DT, Branch AD. Costs of telaprevir-based triple therapy for hepatitis C: $189,000 per sustained virological response. Hepatology. 2014 Oct; 60(4):1187-95.
    View in: PubMed
  9. Heaton NS, Langlois RA, Sachs D, Lim JK, Palese P, tenOever BR. Long-term survival of influenza virus infected club cells drives immunopathology. J Exp Med. 2014 Aug 25; 211(9):1707-14.
    View in: PubMed
  10. Scalea JR, Okumi M, Villani V, Shimizu A, Nishimura H, Gillon BC, Torabi R, Cormack T, Moran S, LeGuern C, Sachs DH, Yamada K. Abrogation of Renal Allograft Tolerance in MGH Miniature Swine: The Role of Intra-Graft and Peripheral Factors in Long-Term Tolerance. Am J Transplant. 2014 Sep; 14(9):2001-10.
    View in: PubMed
  11. Yeh H, Machaidze Z, Wamala I, Fraser JW, Navarro-Alvarez N, Kim K, Schuetz C, Shi S, Zhu A, Hertl M, Elias N, Farkash EA, Vagefi PA, Varma M, Smith RN, Robson SC, Van Cott EM, Sachs DH, Markmann JF. Increased transfusion-free survival following auxiliary pig liver xenotransplantation. Xenotransplantation. 2014 Sep; 21(5):454-64.
    View in: PubMed
  12. Albritton A, Leonard DA, Barone AL, Keegan J, Mallard C, Sachs DH, Kurtz JM, Cetrulo CL. Lack of Cross-Sensitization Between a-1,3-Galactosyltransferase Knockout Porcine and Allogeneic Skin Grafts Permits Serial Grafting. Transplantation. 2014 Jun 27; 97(12):1209-15.
    View in: PubMed
  13. Backes S, Langlois RA, Schmid S, Varble A, Shim JV, Sachs D, tenOever BR. The Mammalian response to virus infection is independent of small RNA silencing. Cell Rep. 2014 Jul 10; 8(1):114-25.
    View in: PubMed
  14. Kawai T, Sachs DH, Sprangers B, Spitzer TR, Saidman SL, Zorn E, Tolkoff-Rubin N, Preffer F, Crisalli K, Gao B, Wong W, Morris H, LoCascio SA, Sayre P, Shonts B, Williams WW, Smith RN, Colvin RB, Sykes M, Cosimi AB. Long-Term Results in Recipients of Combined HLA-Mismatched Kidney and Bone Marrow Transplantation Without Maintenance Immunosuppression. Am J Transplant. 2014 Jul; 14(7):1599-611.
    View in: PubMed
  15. Tena A, Sachs DH. Stem cells: immunology and immunomodulation. Dev Ophthalmol. 2014; 53:122-32.
    View in: PubMed
  16. Lee PW, Hanekamp JS, Villani V, Vagefi PA, Cina RA, Kamano C, O'Malley PE, Arn S, Yamada K, Sachs DH. Evidence for a gene controlling the induction of transplantation tolerance. Am J Transplant. 2014 Apr; 14(4):952-9.
    View in: PubMed
  17. Peraino JS, Zhang H, Rajasekera PV, Wei M, Madsen JC, Sachs DH, Huang CA, Wang Z. Diphtheria toxin-based bivalent human IL-2 fusion toxin with improved efficacy for targeting human CD25(+) cells. J Immunol Methods. 2014 Mar; 405:57-66.
    View in: PubMed
  18. Leonard DA, Kurtz JM, Mallard C, Albritton A, Duran-Struuck R, Farkash EA, Crepeau R, Matar A, Horner BM, Randolph MA, Sachs DH, Huang CA, Cetrulo CL. Vascularized composite allograft tolerance across MHC barriers in a large animal model. Am J Transplant. 2014 Feb; 14(2):343-55.
    View in: PubMed
  19. Sachs DH, Kawai T, Sykes M. Induction of Tolerance through Mixed Chimerism. Cold Spring Harb Perspect Med. 2014; 4(1).
    View in: PubMed
  20. Cetrulo CL, Torabi R, Scalea JR, Shimizu A, Leto Barone AA, Gillon BC, Tasaki M, Leonard DA, Cormack TA, Villani V, Randolph MA, Sachs DH, Yamada K. Vascularized composite allograft transplant survival in miniature Swine: is MHC tolerance sufficient for acceptance of epidermis? Transplantation. 2013 Dec 15; 96(11):966-74.
    View in: PubMed
  21. Heaton NS, Sachs D, Chen CJ, Hai R, Palese P. Genome-wide mutagenesis of influenza virus reveals unique plasticity of the hemagglutinin and NS1 proteins. Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):20248-53.
    View in: PubMed
  22. Liang F, Wamala I, Scalea J, Tena A, Cormack T, Pratts S, Duran-Struuck R, Elias N, Hertl M, Huang CA, Sachs DH. Increased levels of anti-non-Gal IgG following pig-to-baboon bone marrow transplantation correlate with failure of engraftment. Xenotransplantation. 2013 Nov; 20(6):458-68.
    View in: PubMed
  23. Wamala I, Matar AJ, Farkash E, Wang Z, Huang CA, Sachs DH. Recombinant anti-monkey CD3 immunotoxin depletes peripheral lymph node T lymphocytes more effectively than rabbit anti-thymocyte globulin in naïve baboons. Transpl Immunol. 2013 Dec; 29(1-4):60-3.
    View in: PubMed
  24. Peraino JS, Schenk M, Li G, Zhang H, Farkash EA, Sachs DH, Huang CA, Duran-Struuck R, Wang Z. Development of a diphtheria toxin-based recombinant porcine IL-2 fusion toxin for depleting porcine CD25(+) cells. J Immunol Methods. 2013 Dec 15; 398-399:33-43.
    View in: PubMed
  25. Varble A, Benitez AA, Schmid S, Sachs D, Shim JV, Rodriguez-Barrueco R, Panis M, Crumiller M, Silva JM, Sachidanandam R, tenOever BR. An in vivo RNAi screening approach to identify host determinants of virus replication. Cell Host Microbe. 2013 Sep 11; 14(3):346-56.
    View in: PubMed
  26. Vallabhajosyula P, Hirakata A, Shimizu A, Okumi M, Tchipashvili V, Hong H, Yamada K, Sachs DH. Assessing the effect of immunosuppression on engraftment of pancreatic islets. Transplantation. 2013 Aug 27; 96(4):372-8.
    View in: PubMed
  27. Madariaga ML, Michel SG, Tasaki M, Villani V, La Muraglia GM, Sihag S, Gottschall J, Farkash EA, Shimizu A, Allan JS, Sachs DH, Yamada K, Madsen JC. Induction of cardiac allograft tolerance across a full MHC barrier in miniature swine by donor kidney cotransplantation. Am J Transplant. 2013 Oct; 13(10):2558-66.
    View in: PubMed
  28. Kawai T, Sachs DH. Tolerance induction: hematopoietic chimerism. Curr Opin Organ Transplant. 2013 Aug; 18(4):402-7.
    View in: PubMed
  29. Kawai T, Sachs DH, Sykes M, Cosimi AB. HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med. 2013 May 9; 368(19):1850-2.
    View in: PubMed
  30. Shimatsu Y, Yamada K, Horii W, Hirakata A, Sakamoto Y, Waki S, Sano J, Saitoh T, Sahara H, Shimizu A, Yazawa H, Sachs DH, Nunoya T. Production of cloned NIBS (Nippon Institute for Biological Science) and a-1, 3-galactosyltransferase knockout MGH miniature pigs by somatic cell nuclear transfer using the NIBS breed as surrogates. Xenotransplantation. 2013 May; 20(3):157-64.
    View in: PubMed
  31. Eriksson E, Rohrich RJ, Sachs DH, Pomahac B, Delmonico FL, Caterson EJ, Goldwyn RM. The nobler angels of our nature: a tribute to Joseph E. Murray, M.D., 1919 to 2012. Plast Reconstr Surg. 2013 Apr; 131(4):912-7.
    View in: PubMed
  32. Brandacher G, Sachs DH, Thomson AW. Immunology of vascularized composite allografts. Clin Dev Immunol. 2013; 2013:689071.
    View in: PubMed
  33. Okumi M, Scalea JR, Gillon BC, Tasaki M, Villani V, Cormack T, Hirakata A, Shimizu A, Sachs DH, Yamada K. The induction of tolerance of renal allografts by adoptive transfer in miniature swine. Am J Transplant. 2013 May; 13(5):1193-202.
    View in: PubMed
  34. Peraino JS, Schenk M, Zhang H, Li G, Hermanrud CE, Neville DM, Sachs DH, Huang CA, Duran-Struuck R, Wang Z. A truncated diphtheria toxin based recombinant porcine CTLA-4 fusion toxin. J Immunol Methods. 2013 May 31; 391(1-2):103-11.
    View in: PubMed
  35. Leonard DA, Cetrulo CL, McGrouther DA, Sachs DH. Induction of tolerance of vascularized composite allografts. Transplantation. 2013 Feb 15; 95(3):403-9.
    View in: PubMed
  36. Bradley JA, Hardy M, Neuberger J, Sachs D, Suthanthiran M, Wood K. Transplantation: a report of progress. Transplantation. 2013 Jan 15; 95(1):1.
    View in: PubMed
  37. Cosimi AB, Sachs DH, Sykes M, Kawai T. Clinical strategy for induction of transplantation tolerance through mixed chimerism. Clin Transpl. 2013; 127-34.
    View in: PubMed
  38. Weiner J, Scalea J, Ishikawa Y, Okumi M, Griesemer A, Hirakata A, Etter J, Gillon B, Moran S, Shimizu A, Yamada K, Sachs DH. Tolerogenicity of donor major histocompatibility complex-matched skin grafts in previously tolerant Massachusetts general hospital miniature swine. Transplantation. 2012 Dec 27; 94(12):1192-9.
    View in: PubMed
  39. Matar AJ, Crepeau RL, Pathiraja V, Robson S, Fishman JA, Spitzer TR, Sachs DH, Huang CA, Duran-Struuck R. Effects of mobilization regimens in donors on outcomes of hematopoietic cell transplantation in miniature Swine. Comp Med. 2012 Dec; 62(6):487-94.
    View in: PubMed
  40. Duran-Struuck R, Matar A, Crepeau R, Gusha A, Schenk M, Hanekamp I, Pathiraja V, Spitzer TR, Sachs DH, Huang CA. Lack of antidonor alloantibody does not indicate lack of immune sensitization: studies of graft loss in a haploidentical hematopoietic cell transplantation swine model. Biol Blood Marrow Transplant. 2012 Nov; 18(11):1629-37.
    View in: PubMed
  41. Crepeau R, Matar A, Spitzer TR, Robson S, Pathiraja V, Sachs DH, Huang CA, Duran-Struuck R. Edema and tetraparesis in a miniature pig after allogeneic hematopoietic cell transplantation. Comp Med. 2012 Aug; 62(4):298-302.
    View in: PubMed
  42. Kim K, Schuetz C, Elias N, Veillette GR, Wamala I, Varma M, Smith RN, Robson SC, Cosimi AB, Sachs DH, Hertl M. Up to 9-day survival and control of thrombocytopenia following alpha1,3-galactosyl transferase knockout swine liver xenotransplantation in baboons. Xenotransplantation. 2012 Jul-Aug; 19(4):256-64.
    View in: PubMed
  43. Leto Barone AA, Leonard DA, Torabi R, Mallard C, Glor T, Scalea JR, Randolph MA, Sachs DH, Cetrulo CL. The gracilis myocutaneous free flap in swine: an advantageous preclinical model for vascularized composite allograft transplantation research. Microsurgery. 2013 Jan; 33(1):51-5.
    View in: PubMed
  44. Matar AJ, Pathiraja V, Wang Z, Duran-Struuck R, Gusha A, Crepeau R, Tasaki M, Sachs DH, Huang CA. Effect of pre-existing anti-diphtheria toxin antibodies on T cell depletion levels following diphtheria toxin-based recombinant anti-monkey CD3 immunotoxin treatment. Transpl Immunol. 2012 Aug; 27(1):52-4.
    View in: PubMed
  45. Peraino JS, Hermanrud CE, Springett L, Zhang H, Li G, Srinivasan S, Gusha A, Sachs DH, Huang CA, Wang Z. Expression and characterization of recombinant soluble porcine CD3 ectodomain molecules: mapping the epitope of an anti-porcine CD3 monoclonal antibody 898H2-6-15. Cell Immunol. 2012 Mar-Apr; 276(1-2):162-7.
    View in: PubMed
  46. Peraino J, Zhang H, Hermanrud CE, Li G, Sachs DH, Huang CA, Wang Z. Expression and purification of soluble porcine CTLA-4 in yeast Pichia pastoris. Protein Expr Purif. 2012 Apr; 82(2):270-8.
    View in: PubMed
  47. Meltzer AJ, Veillette GR, Aoyama A, Kim KM, Cochrane ME, Wain JC, Madsen JC, Sachs DH, Rosengard BR, Allan JS. Donor brain death inhibits tolerance induction in miniature swine recipients of fully MHC-disparate pulmonary allografts. Am J Transplant. 2012 May; 12(5):1290-5.
    View in: PubMed
  48. Oku M, Okumi M, Shimizu A, Sahara H, Setoyama K, Nishimura H, Sada M, Scalea J, Ido A, Sachs DH, Tsubouchi H, Yamada K. Hepatocyte growth factor sustains T regulatory cells and prolongs the survival of kidney allografts in major histocompatibility complex-inbred CLAWN-miniature swine. Transplantation. 2012 Jan 27; 93(2):148-55.
    View in: PubMed
  49. Leonard DA, Gordon CR, Sachs DH, Cetrulo CL. Immunobiology of face transplantation. J Craniofac Surg. 2012 Jan; 23(1):268-71.
    View in: PubMed
  50. Hermanrud CE, Pathiraja V, Matar A, Duran-Struuck R, Crepeau RL, Srinivasan S, Sachs DH, Huang CA, Wang Z. Expression and purification of non-N-glycosylated porcine interleukin 3 in yeast Pichia pastoris. Protein Expr Purif. 2012 Mar; 82(1):70-4.
    View in: PubMed
  51. Shimizu A, Yamada K, Robson SC, Sachs DH, Colvin RB. Pathologic characteristics of transplanted kidney xenografts. J Am Soc Nephrol. 2012 Feb; 23(2):225-35.
    View in: PubMed
  52. Yamada Y, Boskovic S, Aoyama A, Murakami T, Putheti P, Smith RN, Ochiai T, Nadazdin O, Koyama I, Boenisch O, Najafian N, Bhasin MK, Colvin RB, Madsen JC, Strom TB, Sachs DH, Benichou G, Cosimi AB, Kawai T. Overcoming memory T-cell responses for induction of delayed tolerance in nonhuman primates. Am J Transplant. 2012 Feb; 12(2):330-40.
    View in: PubMed
  53. Nadazdin O, Boskovic S, Wee SL, Sogawa H, Koyama I, Colvin RB, Smith RN, Tocco G, O'Connor DH, Karl JA, Madsen JC, Sachs DH, Kawai T, Cosimi AB, Benichou G. Contributions of direct and indirect alloresponses to chronic rejection of kidney allografts in nonhuman primates. J Immunol. 2011 Nov 1; 187(9):4589-97.
    View in: PubMed
  54. Nishimura H, Scalea J, Wang Z, Shimizu A, Moran S, Gillon B, Sachs DH, Yamada K. First experience with the use of a recombinant CD3 immunotoxin as induction therapy in pig-to-primate xenotransplantation: the effect of T-cell depletion on outcome. Transplantation. 2011 Sep 27; 92(6):641-7.
    View in: PubMed
  55. Vallabhajosyula P, Tena A, Yamada K, Sachs DH. Signal joint T-cell receptor excision circle assay in miniature swine. Transplantation. 2011 Sep 27; 92(6):634-40.
    View in: PubMed
  56. Yamada K, Hirakata A, Tchipashvili V, Shimizu A, Iwaki H, Griesemer A, Vallabhajosyula P, Moran S, Sachs DH. Composite islet-kidneys from single baboon donors cure diabetes across fully allogenic barriers. Am J Transplant. 2011 Dec; 11(12):2603-12.
    View in: PubMed
  57. Wang Z, Duran-Struuck R, Crepeau R, Matar A, Hanekamp I, Srinivasan S, Neville DM, Sachs DH, Huang CA. Development of a diphtheria toxin based antiporcine CD3 recombinant immunotoxin. Bioconjug Chem. 2011 Oct 19; 22(10):2014-20.
    View in: PubMed
  58. Sachs DH, Cone JL. A mouse B-cell alloantigen determined by gene(s) linked to the major histocompatibility complex. The Journal of Experimental Medicine. 1973. 138: 1289-1304. J Immunol. 2011 Sep 1; 187(5):2045-60.
    View in: PubMed
  59. Sachs DH, Sykes M, Kawai T, Cosimi AB. Immuno-intervention for the induction of transplantation tolerance through mixed chimerism. Semin Immunol. 2011 Jun; 23(3):165-73.
    View in: PubMed
  60. Kawai T, Cosimi AB, Sachs DH. Preclinical and clinical studies on the induction of renal allograft tolerance through transient mixed chimerism. Curr Opin Organ Transplant. 2011 Aug; 16(4):366-71.
    View in: PubMed
  61. Spitzer TR, Sachs DH, Cosimi B. Multiple myeloma. N Engl J Med. 2011 Jun 16; 364(24):2364; author reply 2364.
    View in: PubMed
  62. Veillette GR, Sahara H, Meltzer AJ, Weiss MJ, Iwamoto Y, Kim KM, Rosengard BR, Allan JS, Houser SL, Sachs DH, Benichou G, Madsen JC. Autoimmune sensitization to cardiac myosin leads to acute rejection of cardiac allografts in miniature swine. Transplantation. 2011 Jun 15; 91(11):1187-91.
    View in: PubMed
  63. Farris AB, Taheri D, Kawai T, Fazlollahi L, Wong W, Tolkoff-Rubin N, Spitzer TR, Iafrate AJ, Preffer FI, Locascio SA, Sprangers B, Saidman S, Smith RN, Cosimi AB, Sykes M, Sachs DH, Colvin RB. Acute renal endothelial injury during marrow recovery in a cohort of combined kidney and bone marrow allografts. Am J Transplant. 2011 Jul; 11(7):1464-77.
    View in: PubMed
  64. Nadazdin O, Boskovic S, Murakami T, Tocco G, Smith RN, Colvin RB, Sachs DH, Allan J, Madsen JC, Kawai T, Cosimi AB, Benichou G. Host alloreactive memory T cells influence tolerance to kidney allografts in nonhuman primates. Sci Transl Med. 2011 Jun 8; 3(86):86ra51.
    View in: PubMed
  65. Andreola G, Chittenden M, Shaffer J, Cosimi AB, Kawai T, Cotter P, Locascio SA, Morokata T, Dey BR, Tolkoff-Rubin NT, Preffer F, Bonnefoix T, Kattleman K, Spitzer TR, Sachs DH, Sykes M. Mechanisms of donor-specific tolerance in recipients of haploidentical combined bone marrow/kidney transplantation. Am J Transplant. 2011 Jun; 11(6):1236-47.
    View in: PubMed
  66. Sachs DH. Transplant tolerance: bench to bedside--26th annual Samuel Jason Mixter Lecture. Arch Surg. 2011 May; 146(5):501-5.
    View in: PubMed
  67. Spitzer TR, Sykes M, Tolkoff-Rubin N, Kawai T, McAfee SL, Dey BR, Ballen K, Delmonico F, Saidman S, Sachs DH, Cosimi AB. Long-term follow-up of recipients of combined human leukocyte antigen-matched bone marrow and kidney transplantation for multiple myeloma with end-stage renal disease. Transplantation. 2011 Mar 27; 91(6):672-6.
    View in: PubMed
  68. Tena A, Vallabhajosyula P, Hawley RJ, Griesemer A, Yamada K, Sachs DH. Quantification of baboon thymopoiesis in porcine thymokidney xenografts by the signal-joining T-cell receptor excision circle assay. Transplantation. 2011 Mar 27; 91(6):639-44.
    View in: PubMed
  69. Sachs DH. Mark Pescovitz, M.D. (1955-2010). Transplantation. 2011 Mar 15; 91(5):487-8.
    View in: PubMed
  70. Nguyen BN, Azimzadeh AM, Schroeder C, Buddensick T, Zhang T, Laaris A, Cochrane M, Schuurman HJ, Sachs DH, Allan JS, Pierson RN. Absence of Gal epitope prolongs survival of swine lungs in an ex vivo model of hyperacute rejection. Xenotransplantation. 2011 Mar-Apr; 18(2):94-107.
    View in: PubMed
  71. LoCascio SA, Morokata T, Chittenden M, Preffer FI, Dombkowski DM, Andreola G, Crisalli K, Kawai T, Saidman SL, Spitzer TR, Tolkoff-Rubin N, Cosimi AB, Sachs DH, Sykes M. Mixed chimerism, lymphocyte recovery, and evidence for early donor-specific unresponsiveness in patients receiving combined kidney and bone marrow transplantation to induce tolerance. Transplantation. 2010 Dec 27; 90(12):1607-15.
    View in: PubMed
  72. Bradley JA, Hardy M, Neuberger J, Sachs D, Suthanthiran M, Wood K, Monaco AP, Morris PJ. Transplantation: a report of progress. Transplantation. 2010 Dec 27; 90(12):1245.
    View in: PubMed
  73. Lutton BV, Cho PS, Hirsh EL, Ferguson KK, Teague AG, Hanekamp JS, Chi N, Goldman SN, Messina DJ, Houser S, Yeap BY, Popma SH, Sachs DH, Huang CA. Approaches to avoid immune responses induced by repeated subcutaneous injections of allogeneic umbilical cord tissue-derived cells. Transplantation. 2010 Sep 15; 90(5):494-501.
    View in: PubMed
  74. Hirakata A, Okumi M, Griesemer AD, Shimizu A, Nobori S, Tena A, Moran S, Arn S, Boyd RL, Sachs DH, Yamada K. Reversal of age-related thymic involution by an LHRH agonist in miniature swine. Transpl Immunol. 2010 Oct; 24(1):76-81.
    View in: PubMed
  75. Griesemer A, Liang F, Hirakata A, Hirsh E, Lo D, Okumi M, Sykes M, Yamada K, Huang CA, Sachs DH. Occurrence of specific humoral non-responsiveness to swine antigens following administration of GalT-KO bone marrow to baboons. Xenotransplantation. 2010 Jul-Aug; 17(4):300-12.
    View in: PubMed
  76. Nadazdin O, Boskovic S, Murakami T, O'Connor DH, Wiseman RW, Karl JA, Tuscher JJ, Sachs DH, Madsen JC, Tocco G, Kawai T, Cosimi AB, Benichou G. Phenotype, distribution and alloreactive properties of memory T cells from cynomolgus monkeys. Am J Transplant. 2010 Jun; 10(6):1375-84.
    View in: PubMed
  77. Nadazdin O, Abrahamian G, Boskovic S, Smith RN, Schoenfeld DA, Madsen JC, Colvin RB, Sachs DH, Cosimi AB, Kawai T. Stem cell mobilization and collection for induction of mixed chimerism and renal allograft tolerance in cynomolgus monkeys. J Surg Res. 2011 Jun 15; 168(2):294-300.
    View in: PubMed
  78. Weiner J, Yamada K, Ishikawa Y, Moran S, Etter J, Shimizu A, Smith RN, Sachs DH. Prolonged survival of GalT-KO swine skin on baboons. Xenotransplantation. 2010 Mar-Apr; 17(2):147-52.
    View in: PubMed
  79. Duran-Struuck R, Cho PS, Teague AG, Fishman B, Fishman AS, Hanekamp JS, Moran SG, Wikiel KJ, Ferguson KK, Lo DP, Duggan M, Arn JS, Billiter B, Horner B, Houser S, Yeap BY, Westmoreland SV, Spitzer TR, McMorrow IM, Sachs DH, Bronson RT, Huang CA. Myelogenous leukemia in adult inbred MHC-defined miniature swine: a model for human myeloid leukemias. Vet Immunol Immunopathol. 2010 Jun 15; 135(3-4):243-56.
    View in: PubMed
  80. Mulder A, Kardol MJ, Arn JS, Eijsink C, Franke ME, Schreuder GM, Haasnoot GW, Doxiadis II, Sachs DH, Smith DM, Claas FH. Human monoclonal HLA antibodies reveal interspecies crossreactive swine MHC class I epitopes relevant for xenotransplantation. Mol Immunol. 2010 Jan; 47(4):809-15.
    View in: PubMed
  81. Griesemer AD, Hirakata A, Shimizu A, Moran S, Tena A, Iwaki H, Ishikawa Y, Schule P, Arn JS, Robson SC, Fishman JA, Sykes M, Sachs DH, Yamada K. Results of gal-knockout porcine thymokidney xenografts. Am J Transplant. 2009 Dec; 9(12):2669-78.
    View in: PubMed
  82. Porcheray F, Wong W, Saidman SL, De Vito J, Girouard TC, Chittenden M, Shaffer J, Tolkoff-Rubin N, Dey BR, Spitzer TR, Colvin RB, Cosimi AB, Kawai T, Sachs DH, Sykes M, Zorn E. B-cell immunity in the context of T-cell tolerance after combined kidney and bone marrow transplantation in humans. Am J Transplant. 2009 Sep; 9(9):2126-35.
    View in: PubMed
  83. Hanekamp JS, Okumi M, Tena A, Arn S, Yamada K, Sachs DH. Cytoplasmic inheritance of transplantation antigens in animals produced by nuclear transfer. Transplantation. 2009 Jul 15; 88(1):30-7.
    View in: PubMed
  84. Medarova Z, Vallabhajosyula P, Tena A, Evgenov N, Pantazopoulos P, Tchipashvili V, Weir G, Sachs D, Moore A. In vivo imaging of autologous islet grafts in the liver and under the kidney capsule in non-human primates. Transplantation. 2009 Jun 15; 87(11):1659-66.
    View in: PubMed
  85. Knosalla C, Yazawa K, Behdad A, Bodyak N, Shang H, Bühler L, Houser S, Gollackner B, Griesemer A, Schmitt-Knosalla I, Schuurman HJ, Awwad M, Sachs DH, Cooper DK, Yamada K, Usheva A, Robson SC. Renal and cardiac endothelial heterogeneity impact acute vascular rejection in pig-to-baboon xenotransplantation. Am J Transplant. 2009 May; 9(5):1006-16.
    View in: PubMed
  86. Sachs DH, Galli C. Genetic manipulation in pigs. Curr Opin Organ Transplant. 2009 Apr; 14(2):148-53.
    View in: PubMed
  87. Weiss MJ, Guenther DA, Mezrich JD, Sahara H, Ng CY, Meltzer AJ, Sayre JK, Cochrane ME, Pujara AC, Houser SL, Sachs DH, Rosengard BR, Allan JS, Benichou G, Madsen JC. The indirect alloresponse impairs the induction but not maintenance of tolerance to MHC class I-disparate allografts. Am J Transplant. 2009 Jan; 9(1):105-13.
    View in: PubMed
  88. Bradley JA, Hardy M, Neuberger J, Sachs D, Suthanthiran M, Wood K, Monaco AP, Morris PJ. Transplantation: a report of progress. Transplantation. 2008 Dec 27; 86(12):1635.
    View in: PubMed
  89. Meltzer AJ, Weiss MJ, Veillette GR, Sahara H, Ng CY, Cochrane ME, Houser SL, Sachs DH, Rosengard BR, Madsen JC, Wain JC, Allan JS. Repetitive gastric aspiration leads to augmented indirect allorecognition after lung transplantation in miniature swine. Transplantation. 2008 Dec 27; 86(12):1824-9.
    View in: PubMed
  90. Sachs DH, Sykes M, Yamada K. Achieving tolerance in pig-to-primate xenotransplantation: reality or fantasy. Transpl Immunol. 2009 Jun; 21(2):101-5.
    View in: PubMed
  91. Hisashi Y, Yamada K, Kuwaki K, Tseng YL, Dor FJ, Houser SL, Robson SC, Schuurman HJ, Cooper DK, Sachs DH, Colvin RB, Shimizu A. Rejection of cardiac xenografts transplanted from alpha1,3-galactosyltransferase gene-knockout (GalT-KO) pigs to baboons. Am J Transplant. 2008 Dec; 8(12):2516-26.
    View in: PubMed
  92. Issa NC, Wilkinson RA, Griesemer A, Cooper DK, Yamada K, Sachs DH, Fishman JA. Absence of replication of porcine endogenous retrovirus and porcine lymphotropic herpesvirus type 1 with prolonged pig cell microchimerism after pig-to-baboon xenotransplantation. J Virol. 2008 Dec; 82(24):12441-8.
    View in: PubMed
  93. Griesemer AD, Lamattina JC, Okumi M, Etter JD, Shimizu A, Sachs DH, Yamada K. Linked suppression across an MHC-mismatched barrier in a miniature swine kidney transplantation model. J Immunol. 2008 Sep 15; 181(6):4027-36.
    View in: PubMed
  94. Sogawa H, Boskovic S, Nadazdin O, Abrahamian G, Colvin RB, Sachs DH, Cosimi AB, Kawai T. Limited efficacy and unacceptable toxicity of cyclophosphamide for the induction of mixed chimerism and renal allograft tolerance in cynomolgus monkeys. Transplantation. 2008 Aug 27; 86(4):615-9.
    View in: PubMed
  95. Sachs DH, Kawai T, Colvin RB, Fishman JA, Sykes M, Cosimi AB. Response to 'Tolerance versus immunosuppression: a perspective'. Am J Transplant. 2008 Aug; 8(8):1573-4.
    View in: PubMed
  96. Smith RN, Kawai T, Boskovic S, Nadazdin O, Sachs DH, Cosimi AB, Colvin RB. Four stages and lack of stable accommodation in chronic alloantibody-mediated renal allograft rejection in Cynomolgus monkeys. Am J Transplant. 2008 Aug; 8(8):1662-72.
    View in: PubMed
  97. Traum AZ, Kawai T, Vacanti JP, Sachs DH, Cosimi AB, Madsen JC. The need for tolerance in pediatric organ transplantation. Pediatrics. 2008 Jun; 121(6):1258-60.
    View in: PubMed
  98. Shimizu A, Hisashi Y, Kuwaki K, Tseng YL, Dor FJ, Houser SL, Robson SC, Schuurman HJ, Cooper DK, Sachs DH, Yamada K, Colvin RB. Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from alpha1,3-galactosyltransferase gene-knockout pigs in baboons. Am J Pathol. 2008 Jun; 172(6):1471-81.
    View in: PubMed
  99. Hoerbelt R, Benjamin CL, Shoji T, Houser SL, Muniappan A, Hasse RS, Ledgerwood LG, Allan JS, Sachs DH, Madsen JC. The effects of tolerance on allograft damage caused by the innate immune system. Transplantation. 2008 Feb 15; 85(3):314-22.
    View in: PubMed
  100. Sachs DH. Patents and research: friends or foes? Surgery. 2008 Feb; 143(2):191-3.
    View in: PubMed
  101. Okumi M, Fishbein JM, Griesemer AD, Gianello PR, Hirakata A, Nobori S, Moran S, Samelson-Jones E, Shimizu A, Sachs DH, Yamada K. Role of persistence of antigen and indirect recognition in the maintenance of tolerance to renal allografts. Transplantation. 2008 Jan 27; 85(2):270-80.
    View in: PubMed
  102. Kawai T, Cosimi AB, Spitzer TR, Tolkoff-Rubin N, Suthanthiran M, Saidman SL, Shaffer J, Preffer FI, Ding R, Sharma V, Fishman JA, Dey B, Ko DS, Hertl M, Goes NB, Wong W, Williams WW, Colvin RB, Sykes M, Sachs DH. HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med. 2008 Jan 24; 358(4):353-61.
    View in: PubMed
  103. Sachs DH. The lure of transplantation. Clin Transpl. 2008; 287-305.
    View in: PubMed
  104. Shoji T, Sahara H, Muniappan A, Guenther DA, Wain JC, Houser SL, Bravard MA, Pujara AC, Hasse RS, Sachs DH, Madsen JC, Allan JS. Operational tolerance to class I disparate lungs can be induced despite pretransplant immunization with class I allopeptides. Transplantation. 2007 Dec 15; 84(11):1467-73.
    View in: PubMed
  105. Cho PS, Messina DJ, Hirsh EL, Chi N, Goldman SN, Lo DP, Harris IR, Popma SH, Sachs DH, Huang CA. Immunogenicity of umbilical cord tissue derived cells. Blood. 2008 Jan 1; 111(1):430-8.
    View in: PubMed
  106. Cho PS, Lo DP, Wikiel KJ, Rowland HC, Coburn RC, McMorrow IM, Goodrich JG, Arn JS, Billiter RA, Houser SL, Shimizu A, Yang YG, Sachs DH, Huang CA. Establishment of transplantable porcine tumor cell lines derived from MHC-inbred miniature swine. Blood. 2007 Dec 1; 110(12):3996-4004.
    View in: PubMed
  107. Hongo D, Hadidi S, Damrauer S, Garrigue V, Kraft D, Sachs DH, Nikolic B, Sykes M. Porcine thymic grafts protect human thymocytes from HIV-1-induced destruction. J Infect Dis. 2007 Sep 15; 196(6):900-10.
    View in: PubMed
  108. Sachs DH, Yamada K, Robson SC, Fishman JA, Shimizu A, Colvin RB, Sykes M. GalT-KO pigs: is the cup half empty or half full? Transplantation. 2007 Jul 15; 84(1):12-4.
    View in: PubMed
  109. Shaffer J, Villard J, Means TK, Alexander S, Dombkowski D, Dey BR, McAfee S, Ballen KK, Saidman S, Preffer FI, Sachs DH, Spitzer TR, Sykes M. Regulatory T-cell recovery in recipients of haploidentical nonmyeloablative hematopoietic cell transplantation with a humanized anti-CD2 mAb, MEDI-507, with or without fludarabine. Exp Hematol. 2007 Jul; 35(7):1140-52.
    View in: PubMed
  110. Dey BR, Shaffer J, Yee AJ, McAfee S, Caron M, Power K, Ting DT, Colby C, Preffer F, Ballen K, Attar E, Saidman S, Tarbell N, Sachs D, Sykes M, Spitzer TR. Comparison of outcomes after transplantation of peripheral blood stem cells versus bone marrow following an identical nonmyeloablative conditioning regimen. Bone Marrow Transplant. 2007 Jul; 40(1):19-27.
    View in: PubMed
  111. Nguyen BN, Azimzadeh AM, Zhang T, Wu G, Schuurman HJ, Shuurman HJ, Sachs DH, Ayares D, Allan JS, Pierson RN. Life-supporting function of genetically modified swine lungs in baboons. J Thorac Cardiovasc Surg. 2007 May; 133(5):1354-63.
    View in: PubMed
  112. Koyama I, Nadazdin O, Boskovic S, Ochiai T, Smith RN, Sykes M, Sogawa H, Murakami T, Strom TB, Colvin RB, Sachs DH, Benichou G, Cosimi AB, Kawai T. Depletion of CD8 memory T cells for induction of tolerance of a previously transplanted kidney allograft. Am J Transplant. 2007 May; 7(5):1055-61.
    View in: PubMed
  113. Houser S, Muniappan A, Allan J, Sachs D, Madsen J. Cardiac allograft vasculopathy: real or a normal morphologic variant? J Heart Lung Transplant. 2007 Feb; 26(2):167-73.
    View in: PubMed
  114. Papeta N, Chen T, Vianello F, Gererty L, Malik A, Mok YT, Tharp WG, Bagley J, Zhao G, Stevceva L, Yoon V, Sykes M, Sachs D, Iacomini J, Poznansky MC. Long-term survival of transplanted allogeneic cells engineered to express a T cell chemorepellent. Transplantation. 2007 Jan 27; 83(2):174-83.
    View in: PubMed
  115. Doucette K, Dor FJ, Wilkinson RA, Martin SI, Huang CA, Cooper DK, Sachs DH, Fishman JA. Gene expression of porcine lymphotrophic herpesvirus-1 in miniature Swine with posttransplant lymphoproliferative disorder. Transplantation. 2007 Jan 15; 83(1):87-90.
    View in: PubMed
  116. Vallabhajosyula P, Griesemer A, Yamada K, Sachs DH. Vascularized composite islet-kidney transplantation in a miniature swine model. Cell Biochem Biophys. 2007; 48(2-3):201-7.
    View in: PubMed
  117. Nobori S, Shimizu A, Okumi M, Samelson-Jones E, Griesemer A, Hirakata A, Sachs DH, Yamada K. Thymic rejuvenation and the induction of tolerance by adult thymic grafts. Proc Natl Acad Sci U S A. 2006 Dec 12; 103(50):19081-6.
    View in: PubMed
  118. Sahara H, Weiss MJ, Ng CY, Houser SL, Pujara AC, Sayre JK, Wain JC, Sachs DH, Madsen JC, Allan JS. Thymectomy does not abrogate long-term acceptance of MHC class I-disparate lung allografts in miniature Swine. Transplant Proc. 2006 Dec; 38(10):3253-5.
    View in: PubMed
  119. Horner BM, Cina RA, Wikiel KJ, Lima B, Ghazi A, Lo DP, Yamada K, Sachs DH, Huang CA. Predictors of organ allograft tolerance following hematopoietic cell transplantation. Am J Transplant. 2006 Dec; 6(12):2894-902.
    View in: PubMed
  120. Shoji T, Sahara H, Muniappan A, Guenther DA, Houser SL, Pujara AC, Bravard MA, Wain JC, Sachs DH, Madsen JC, Allan JS. An MHC class II disparity raises the threshold for tolerance induction in pulmonary allografts in miniature swine. Transplant Proc. 2006 Dec; 38(10):3268-70.
    View in: PubMed
  121. Sahara H, Shoji T, Ng CY, Weiss MJ, Muniappan A, Guenther DA, Houser SL, Pujara AC, Sayre JK, Wain JC, Sachs DH, Madsen JC, Allan JS. The role of indirect recognition of MHC class I and II allopeptides in a fully mismatched miniature swine model of lung transplantation. Transplant Proc. 2006 Dec; 38(10):3256-8.
    View in: PubMed
  122. Boskovic S, Kawai T, Smith RN, Wee SL, Nadazdin O, Koyama I, Saidman S, Cardarelli F, Elias N, Sykes M, Strom T, Colvin RB, Sachs DH, Cosimi AB. Monitoring antidonor alloantibodies as a predictive assay for renal allograft tolerance/long-term observations in nonhuman primates. Transplantation. 2006 Sep 27; 82(6):819-25.
    View in: PubMed
  123. Wong BS, Yamada K, Okumi M, Weiner J, O'Malley PE, Tseng YL, Dor FJ, Cooper DK, Saidman SL, Griesemer A, Sachs DH. Allosensitization does not increase the risk of xenoreactivity to alpha1,3-galactosyltransferase gene-knockout miniature swine in patients on transplantation waiting lists. Transplantation. 2006 Aug 15; 82(3):314-9.
    View in: PubMed
  124. Fudaba Y, Spitzer TR, Shaffer J, Kawai T, Fehr T, Delmonico F, Preffer F, Tolkoff-Rubin N, Dey BR, Saidman SL, Kraus A, Bonnefoix T, McAfee S, Power K, Kattleman K, Colvin RB, Sachs DH, Cosimi AB, Sykes M. Myeloma responses and tolerance following combined kidney and nonmyeloablative marrow transplantation: in vivo and in vitro analyses. Am J Transplant. 2006 Sep; 6(9):2121-33.
    View in: PubMed
  125. Smith RN, Kawai T, Boskovic S, Nadazdin O, Sachs DH, Cosimi AB, Colvin RB. Chronic antibody mediated rejection of renal allografts: pathological, serological and immunologic features in nonhuman primates. Am J Transplant. 2006 Aug; 6(8):1790-8.
    View in: PubMed
  126. Tseng YL, Moran K, Dor FJ, Sanderson TM, Li W, Lancos CJ, Schuurman HJ, Sachs DH, Cooper DK. Elicited antibodies in baboons exposed to tissues from alpha1,3-galactosyltransferase gene-knockout pigs. Transplantation. 2006 Apr 15; 81(7):1058-62.
    View in: PubMed
  127. Yamamoto S, Teranishi K, Kamano C, Samelson-Jones E, Arakawa H, Nobori S, Okumi M, Houser S, Shimizu A, Sachs DH, Yamada K. Role of the thymus in transplantation tolerance in miniature swine: V. Deficiency of the graft-to-thymus pathway of tolerance induction in recipients of cardiac transplants. Transplantation. 2006 Feb 27; 81(4):607-13.
    View in: PubMed
  128. Nobori S, Samelson-Jones E, Shimizu A, Hisashi Y, Yamamoto S, Kamano C, Teranishi K, Vagefi PA, Nuhn M, Okumi M, Wong B, Houser S, Sachs DH, Yamada K. Long-term acceptance of fully allogeneic cardiac grafts by cotransplantation of vascularized thymus in miniature swine. Transplantation. 2006 Jan 15; 81(1):26-35.
    View in: PubMed
  129. Kawai T, Sachs DH, Sykes M, Spitzer T, Tolkoff-Rubin N, Saidman S, Ko D, Dey B, Colvin RB, Cosimi AB. My most interesting cases. Clin Transpl. 2006; 580-2.
    View in: PubMed
  130. Yamamoto S, Lavelle JM, Vagefi PA, Arakawa H, Samelson-Jones E, Moran S, Teranishi K, Kamano C, Fishman J, Awwad M, Neville DM, Shimizu A, Sykes M, Sachs DH, Yamada K. Vascularized thymic lobe transplantation in a pig-to-baboon model: a novel strategy for xenogeneic tolerance induction and T-cell reconstitution. Transplantation. 2005 Dec 27; 80(12):1783-90.
    View in: PubMed
  131. Sachs DH. A knock-out punch? Nat Med. 2005 Dec; 11(12):1271.
    View in: PubMed
  132. Tseng YL, Kuwaki K, Dor FJ, Shimizu A, Houser S, Hisashi Y, Yamada K, Robson SC, Awwad M, Schuurman HJ, Sachs DH, Cooper DK. alpha1,3-Galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 months. Transplantation. 2005 Nov 27; 80(10):1493-500.
    View in: PubMed
  133. Hoerbelt R, Johnston DR, Shoji T, Houser SL, Hasse RS, Ledgerwood LG, Iribarne A, Allan JS, Sayegh MH, Sachs DH, Madsen JC. Combination treatment with donor-specific transfusions and cyclosporine a induces long-term survival of cardiac allografts in miniature Swine. Transplantation. 2005 Nov 15; 80(9):1275-82.
    View in: PubMed
  134. Mathes DW, Solari MG, Randolph MA, Gazelle GS, Yamada K, Huang CA, Sachs DH, Lee WP. Long-term acceptance of renal allografts following prenatal inoculation with adult bone marrow. Transplantation. 2005 Nov 15; 80(9):1300-8.
    View in: PubMed
  135. Kuwaki K, Tseng YL, Dor FJ, Shimizu A, Sachs DH, Cooper DK. Localized myocardial infarction following pig-to-baboon heart transplantation. Xenotransplantation. 2005 Nov; 12(6):489-91.
    View in: PubMed
  136. Rodríguez-Barbosa JI, Haller GW, Zhao G, Sachs DH, Sykes M. Host thymectomy and cyclosporine lead to unstable skin graft tolerance after class I mismatched allogeneic neonatal thymic transplantation in mice. Transpl Immunol. 2005 Oct; 15(1):25-33.
    View in: PubMed
  137. Johnston DR, Muniappan A, Hoerbelt R, Guenther DA, Shoji T, Houser SL, Sachs DH, Madsen JC. Heart and en-bloc thymus transplantation in miniature swine. J Thorac Cardiovasc Surg. 2005 Aug; 130(2):554-9.
    View in: PubMed
  138. Shimizu A, Yamada K, Yamamoto S, Lavelle JM, Barth RN, Robson SC, Sachs DH, Colvin RB. Thrombotic microangiopathic glomerulopathy in human decay accelerating factor-transgenic swine-to-baboon kidney xenografts. J Am Soc Nephrol. 2005 Sep; 16(9):2732-45.
    View in: PubMed
  139. Shoji T, Wain JC, Houser SL, Benjamin LC, Johnston DR, Hoerbelt R, Hasse RS, Lee RS, Muniappan A, Guenther DA, Bravard MA, Ledgerwood LG, Sachs DH, Sayegh MH, Madsen JC, Allan JS. Indirect recognition of MHC class I allopeptides accelerates lung allograft rejection in miniature swine. Am J Transplant. 2005 Jul; 5(7):1626-34.
    View in: PubMed
  140. Mezrich JD, Benjamin LC, Sachs JA, Houser SL, Vagefi PA, Sachs DH, Madsen JC, Yamada K. Role of the thymus and kidney graft in the maintenance of tolerance to heart grafts in miniature swine. Transplantation. 2005 Jun 27; 79(12):1663-73.
    View in: PubMed
  141. Lee PW, Cina RA, Randolph MA, Arellano R, Goodrich J, Rowland H, Huang CA, Sachs DH, Kim HB. In utero bone marrow transplantation induces kidney allograft tolerance across a full major histocompatibility complex barrier in Swine. Transplantation. 2005 May 15; 79(9):1084-90.
    View in: PubMed
  142. Lee PW, Cina RA, Randolph MA, Goodrich J, Rowland H, Arellano R, Kim HB, Sachs DH, Huang CA. Stable multilineage chimerism across full MHC barriers without graft-versus-host disease following in utero bone marrow transplantation in pigs. Exp Hematol. 2005 Mar; 33(3):371-9.
    View in: PubMed
  143. Dey BR, McAfee S, Colby C, Cieply K, Caron M, Saidman S, Preffer F, Shaffer J, Tarbell N, Sackstein R, Sachs D, Sykes M, Spitzer TR. Anti-tumour response despite loss of donor chimaerism in patients treated with non-myeloablative conditioning and allogeneic stem cell transplantation. Br J Haematol. 2005 Feb; 128(3):351-9.
    View in: PubMed
  144. Tseng YL, Tseng YL, Sachs DH, Cooper DK. Porcine hematopoietic progenitor cell transplantation in nonhuman primates: a review of progress. Transplantation. 2005 Jan 15; 79(1):1-9.
    View in: PubMed
  145. Shoji T, Muniappan A, Guenther DA, Wain JC, Houser SL, Hoerbelt R, Benjamin LC, Hasse RS, Bravard MA, Sachs DH, Madsen JC, Allan JS. Long-term acceptance of porcine pulmonary allografts without chronic rejection. Transplant Proc. 2005 Jan-Feb; 37(1):72-4.
    View in: PubMed
  146. Mueller NJ, Kuwaki K, Knosalla C, Dor FJ, Gollackner B, Wilkinson RA, Arn S, Sachs DH, Cooper DK, Fishman JA. Early weaning of piglets fails to exclude porcine lymphotropic herpesvirus. Xenotransplantation. 2005 Jan; 12(1):59-62.
    View in: PubMed
  147. Dor FJ, Kuwaki K, Tseng YL, Shimizu A, Houser SL, Yamada K, Hawley RJ, Patience C, Awwad M, Fishman JA, Robson SC, Sachs DH, Schuurman HJ, Cooper DK. Potential of aspirin to inhibit thrombotic microangiopathy in alpha1,3-galactosyltransferase gene-knockout pig hearts after transplantation in baboons. Transplant Proc. 2005 Jan-Feb; 37(1):489-90.
    View in: PubMed
  148. Schroeder C, Allan JS, Nguyen BN, Wu G, Zhang T, Azimzadeh AM, Madsen JC, Schuurman HJ, Sachs DH, Pierson RN. Hyperacute rejection is attenuated in GalT knockout swine lungs perfused ex vivo with human blood. Transplant Proc. 2005 Jan-Feb; 37(1):512-3.
    View in: PubMed
  149. Kuwaki K, Tseng YL, Dor FJ, Shimizu A, Houser SL, Sanderson TM, Lancos CJ, Prabharasuth DD, Cheng J, Moran K, Hisashi Y, Mueller N, Yamada K, Greenstein JL, Hawley RJ, Patience C, Awwad M, Fishman JA, Robson SC, Schuurman HJ, Sachs DH, Cooper DK. Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience. Nat Med. 2005 Jan; 11(1):29-31.
    View in: PubMed
  150. Yamada K, Yazawa K, Shimizu A, Iwanaga T, Hisashi Y, Nuhn M, O'Malley P, Nobori S, Vagefi PA, Patience C, Fishman J, Cooper DK, Hawley RJ, Greenstein J, Schuurman HJ, Awwad M, Sykes M, Sachs DH. Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue. Nat Med. 2005 Jan; 11(1):32-4.
    View in: PubMed
  151. Eguchi H, Knosalla C, Lan P, Cheng J, Diouf B, Wang L, Abe M, Schuurman HJ, Sachs DH, Sykes M, Cooper DK, Yang YG. T cells from presensitized donors fail to cause graft-versus-host disease in a pig-to-mouse xenotransplantation model. Transplantation. 2004 Dec 15; 78(11):1609-17.
    View in: PubMed
  152. Mueller NJ, Kuwaki K, Dor FJ, Knosalla C, Gollackner B, Wilkinson RA, Sachs DH, Cooper DK, Fishman JA. Reduction of consumptive coagulopathy using porcine cytomegalovirus-free cardiac porcine grafts in pig-to-primate xenotransplantation. Transplantation. 2004 Nov 27; 78(10):1449-53.
    View in: PubMed
  153. Kawai T, Sogawa H, Boskovic S, Abrahamian G, Smith RN, Wee SL, Andrews D, Nadazdin O, Koyama I, Sykes M, Winn HJ, Colvin RB, Sachs DH, Cosimi AB. CD154 blockade for induction of mixed chimerism and prolonged renal allograft survival in nonhuman primates. Am J Transplant. 2004 Sep; 4(9):1391-8.
    View in: PubMed
  154. Cho PS, Mueller NJ, Cameron AM, Cina RA, Coburn RC, Hettiaratchy S, Melendy E, Neville DM, Patience C, Fishman JA, Sachs DH, Huang CA. Risk factors for the development of post-transplant lymphoproliferative disorder in a large animal model. Am J Transplant. 2004 Aug; 4(8):1274-82.
    View in: PubMed
  155. Dor FJ, Tseng YL, Cheng J, Moran K, Sanderson TM, Lancos CJ, Shimizu A, Yamada K, Awwad M, Sachs DH, Hawley RJ, Schuurman HJ, Cooper DK. alpha1,3-Galactosyltransferase gene-knockout miniature swine produce natural cytotoxic anti-Gal antibodies. Transplantation. 2004 Jul 15; 78(1):15-20.
    View in: PubMed
  156. Knosalla C, Ryan DJ, Moran K, Gollackner B, Schuler W, Sachs DH, Awwad M, Schuurman HJ, Cooper DK. Initial experience with the human anti-human CD154 monoclonal antibody, ABI793, in pig-to-baboon xenotransplantation. Xenotransplantation. 2004 Jul; 11(4):353-60.
    View in: PubMed
  157. Tseng YL, Dor FJ, Kuwaki K, Ryan D, Wood J, Denaro M, Giovino M, Yamada K, Hawley R, Patience C, Schuurman HJ, Awwad M, Sachs DH, Cooper DK. Bone marrow transplantation from alpha1,3-galactosyltransferase gene-knockout pigs in baboons. Xenotransplantation. 2004 Jul; 11(4):361-70.
    View in: PubMed
  158. Kolber-Simonds D, Lai L, Watt SR, Denaro M, Arn S, Augenstein ML, Betthauser J, Carter DB, Greenstein JL, Hao Y, Im GS, Liu Z, Mell GD, Murphy CN, Park KW, Rieke A, Ryan DJ, Sachs DH, Forsberg EJ, Prather RS, Hawley RJ. Production of alpha-1,3-galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations. Proc Natl Acad Sci U S A. 2004 May 11; 101(19):7335-40.
    View in: PubMed
  159. Mezrich J, Yamada K, Sachs DH, Madsen JC. Regulatory T cells generated by the kidney may mediate the beneficial immune effects of combining kidney with heart transplantation. Surgery. 2004 May; 135(5):473-8.
    View in: PubMed
  160. Mueller NJ, Livingston C, Knosalla C, Barth RN, Yamamoto S, Gollackner B, Dor FJ, Buhler L, Sachs DH, Yamada K, Cooper DK, Fishman JA. Activation of porcine cytomegalovirus, but not porcine lymphotropic herpesvirus, in pig-to-baboon xenotransplantation. J Infect Dis. 2004 May 1; 189(9):1628-33.
    View in: PubMed
  161. Vagefi PA, Ierino FL, Gianello PR, Shimizu A, Kamano C, Sachs DH, Yamada K. Role of the thymus in transplantation tolerance in miniature Swine: IV. The thymus is required during the induction phase, but not the maintenance phase, of renal allograft tolerance. Transplantation. 2004 Apr 15; 77(7):979-85.
    View in: PubMed
  162. Cosimi AB, Sachs DH. Mixed chimerism and transplantation tolerance. Transplantation. 2004 Mar 27; 77(6):943-6.
    View in: PubMed
  163. Kamano C, Vagefi PA, Kumagai N, Yamamoto S, Barth RN, LaMattina JC, Moran SG, Sachs DH, Yamada K. Vascularized thymic lobe transplantation in miniature swine: thymopoiesis and tolerance induction across fully MHC-mismatched barriers. Proc Natl Acad Sci U S A. 2004 Mar 16; 101(11):3827-32.
    View in: PubMed
  164. Wood JC, Quinn G, Suling KM, Oldmixon BA, Van Tine BA, Cina R, Arn S, Huang CA, Scobie L, Onions DE, Sachs DH, Schuurman HJ, Fishman JA, Patience C. Identification of exogenous forms of human-tropic porcine endogenous retrovirus in miniature Swine. J Virol. 2004 Mar; 78(5):2494-501.
    View in: PubMed
  165. Kuwaki K, Knosalla C, Dor FJ, Gollackner B, Tseng YL, Houser S, Mueller N, Prabharasuth D, Alt A, Moran K, Cheng J, Behdad A, Sachs DH, Fishman JA, Schuurman HJ, Awwad M, Cooper DK. Suppression of natural and elicited antibodies in pig-to-baboon heart transplantation using a human anti-human CD154 mAb-based regimen. Am J Transplant. 2004 Mar; 4(3):363-72.
    View in: PubMed
  166. Hettiaratchy S, Melendy E, Randolph MA, Coburn RC, Neville DM, Sachs DH, Huang CA, Lee WP. Tolerance to composite tissue allografts across a major histocompatibility barrier in miniature swine. Transplantation. 2004 Feb 27; 77(4):514-21.
    View in: PubMed
  167. Koyama I, Kawai T, Andrews D, Boskovic S, Nadazdin O, Wee SL, Sogawa H, Wu DL, Smith RN, Colvin RB, Sachs DH, Cosimi AB. Thrombophilia associated with anti-CD154 monoclonal antibody treatment and its prophylaxis in nonhuman primates. Transplantation. 2004 Feb 15; 77(3):460-2.
    View in: PubMed
  168. Wu A, Yamada K, Baron C, Mathes DW, Monajati LM, Vagefi PA, Sachs DH. Detection of regulatory cells as an assay for allograft tolerance in miniature swine. J Heart Lung Transplant. 2004 Feb; 23(2):210-7.
    View in: PubMed
  169. Lan P, Wang L, Diouf B, Eguchi H, Su H, Bronson R, Sachs DH, Sykes M, Yang YG. Induction of human T-cell tolerance to porcine xenoantigens through mixed hematopoietic chimerism. Blood. 2004 May 15; 103(10):3964-9.
    View in: PubMed
  170. Houser SL, McMorrow IM, LeGuern C, Schwarze ML, Fuchimoto Y, Sachs DH, Madsen JC. Histomorphometric comparison of cardiac allograft vasculopathy in miniature swine. J Heart Lung Transplant. 2004 Jan; 23(1):50-60.
    View in: PubMed
  171. Menard MT, Schwarze ML, Allan JS, Johnston DR, Mawulawde K, Shimizu A, Yamada K, Houser SL, Allison KS, Sachs DH, Madsen JC. Composite "thymoheart" transplantation improves cardiac allograft survival. Am J Transplant. 2004 Jan; 4(1):79-86.
    View in: PubMed
  172. Quinn G, Wood J, Suling K, Arn S, Sachs DH, Schuurman HJ, Patience C. Genotyping of porcine endogenous retroviruses from a family of miniature swine. J Virol. 2004 Jan; 78(1):314-9.
    View in: PubMed
  173. Knosalla C, Gollackner B, Bühler L, Mueller NJ, Houser S, Mauiyyedi S, Sachs DH, Robson SC, Fishman J, Schuurman HJ, Awwad M, Cooper DK. Correlation of biochemical and hematological changes with graft failure following pig heart and kidney transplantation in baboons. Am J Transplant. 2003 Dec; 3(12):1510-9.
    View in: PubMed
  174. Dawson L, Bateman-House AS, Mueller Agnew D, Bok H, Brock DW, Chakravarti A, Greene M, King PA, O'Brien SJ, Sachs DH, Schill KE, Siegel A, Solter D, Suter SM, Verfaillie CM, Walters LB, Gearhart JD, Faden RR. Safety issues in cell-based intervention trials. Fertil Steril. 2003 Nov; 80(5):1077-85.
    View in: PubMed
  175. Faden RR, Dawson L, Bateman-House AS, Agnew DM, Bok H, Brock DW, Chakravarti A, Gao XJ, Greene M, Hansen JA, King PA, O'Brien SJ, Sachs DH, Schill KE, Siegel A, Solter D, Suter SM, Verfaillie CM, Walters LB, Gearhart JD. Public stem cell banks: considerations of justice in stem cell research and therapy. Hastings Cent Rep. 2003 Nov-Dec; 33(6):13-27.
    View in: PubMed
  176. Gollackner B, Knosalla C, Houser S, Mauiyyedi S, Buhler L, Kawai T, Duggan M, Sachs DH, Awwad M, Cooper DK. Pig kidney transplantation in baboons treated intravenously with a bovine serum albumin-Galalpha1-3Gal conjugate. Xenotransplantation. 2003 Nov; 10(6):606-14.
    View in: PubMed
  177. Lima B, Gleit ZL, Cameron AM, Germana S, Murphy MC, Consorti R, Chang Q, Down JD, LeGuern C, Sachs DH, Huang CA. Engraftment of quiescent progenitors and conversion to full chimerism after nonmyelosuppressive conditioning and hematopoietic cell transplantation in miniature swine. Biol Blood Marrow Transplant. 2003 Sep; 9(9):571-82.
    View in: PubMed
  178. Mezrich JD, Kesselheim JA, Johnston DR, Yamada K, Sachs DH, Madsen JC. The role of regulatory cells in miniature swine rendered tolerant to cardiac allografts by donor kidney cotransplantation. Am J Transplant. 2003 Sep; 3(9):1107-15.
    View in: PubMed
  179. Le Guern AC, Giovino MA, Abe M, Theodore PR, Qi J, Down JD, Sachs DH, Sykes M, Yang YG. Stem cell activity of porcine c-kit+ hematopoietic cells. Exp Hematol. 2003 Sep; 31(9):833-40.
    View in: PubMed
  180. Mueller NJ, Sulling K, Gollackner B, Yamamoto S, Knosalla C, Wilkinson RA, Kaur A, Sachs DH, Yamada K, Cooper DK, Patience C, Fishman JA. Reduced efficacy of ganciclovir against porcine and baboon cytomegalovirus in pig-to-baboon xenotransplantation. Am J Transplant. 2003 Sep; 3(9):1057-64.
    View in: PubMed
  181. Mezrich JD, Yamada K, Lee RS, Mawulawde K, Benjamin LC, Schwarze ML, Maloney ME, Amoah HC, Houser SL, Sachs DH, Madsen JC. Induction of tolerance to heart transplants by simultaneous cotransplantation of donor kidneys may depend on a radiation-sensitive renal-cell population. Transplantation. 2003 Aug 27; 76(4):625-31.
    View in: PubMed
  182. Yamada K, Vagefi PA, Utsugi R, Kitamura H, Barth RN, LaMattina JC, Sachs DH. Thymic transplantation in miniature swine: III. Induction of tolerance by transplantation of composite thymokidneys across fully major histocompatibility complex-mismatched barriers. Transplantation. 2003 Aug 15; 76(3):530-6.
    View in: PubMed
  183. Wu A, Yamada K, Ierino FL, Vagefi PA, Sachs DH. Regulatory mechanism of peripheral tolerance: in vitro evidence for dominant suppression of host responses during the maintenance phase of tolerance to renal allografts in miniature swine. Transpl Immunol. 2003 Jul-Sep; 11(3-4):367-74.
    View in: PubMed
  184. Teranishi K, Alwayn IP, Bühler L, Gollackner B, Knosalla C, Huck J, Duthaler R, Katopodis A, Sachs DH, Schuurman HJ, Awwad M, Cooper DK. Depletion of anti-Gal antibodies by the intravenous infusion of Gal type 2 and 6 glycoconjugates in baboons. Xenotransplantation. 2003 Jul; 10(4):357-67.
    View in: PubMed
  185. Gollackner B, Dor FJ, Knosalla C, Buhler L, Duggan M, Huang CA, Houser SL, Sachs DH, Kawai T, Ko DS, Cooper DK. Spleen transplantation in miniature swine: surgical technique and results in major histocompatibility complex-matched donor and recipient pairs. Transplantation. 2003 Jun 15; 75(11):1799-806.
    View in: PubMed
  186. Gollackner B, Mueller NJ, Houser S, Qawi I, Soizic D, Knosalla C, Buhler L, Dor FJ, Awwad M, Sachs DH, Cooper DK, Robson SC, Fishman JA. Porcine cytomegalovirus and coagulopathy in pig-to-primate xenotransplantation. Transplantation. 2003 Jun 15; 75(11):1841-7.
    View in: PubMed
  187. Zhao Y, Rodriguez-Barbosa JI, Shimizu A, Sachs DH, Sykes M. Despite efficient intrathymic negative selection of host-reactive T cells, autoimmune disease may develop in porcine thymus-grafted athymic mice: evidence for failure of regulatory mechanisms suppressing autoimmunity. Transplantation. 2003 Jun 15; 75(11):1832-40.
    View in: PubMed
  188. Sachs DH. Tolerance: of mice and men. J Clin Invest. 2003 Jun; 111(12):1819-21.
    View in: PubMed
  189. Daly A, McAfee S, Dey B, Colby C, Schulte L, Yeap B, Sackstein R, Tarbell NJ, Sachs D, Sykes M, Spitzer TR. Nonmyeloablative bone marrow transplantation: Infectious complications in 65 recipients of HLA-identical and mismatched transplants. Biol Blood Marrow Transplant. 2003 Jun; 9(6):373-82.
    View in: PubMed
  190. Barth RN, Yamamoto S, LaMattina JC, Kumagai N, Kitamura H, Vagefi PA, Awwad M, Colvin RB, Cooper DK, Sykes M, Sachs DH, Yamada K. Xenogeneic thymokidney and thymic tissue transplantation in a pig-to-baboon model: I. Evidence for pig-specific T-cell unresponsiveness. Transplantation. 2003 May 27; 75(10):1615-24.
    View in: PubMed
  191. Spitzer TR, McAfee SL, Dey BR, Colby C, Hope J, Grossberg H, Preffer F, Shaffer J, Alexander SI, Sachs DH, Sykes M. Nonmyeloablative haploidentical stem-cell transplantation using anti-CD2 monoclonal antibody (MEDI-507)-based conditioning for refractory hematologic malignancies. Transplantation. 2003 May 27; 75(10):1748-51.
    View in: PubMed
  192. Dey BR, McAfee S, Colby C, Sackstein R, Saidman S, Tarbell N, Sachs DH, Sykes M, Spitzer TR. Impact of prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor response in patients with advanced hematologic malignancies treated with nonmyeloablative conditioning and allogeneic bone marrow transplantation. Biol Blood Marrow Transplant. 2003 May; 9(5):320-9.
    View in: PubMed
  193. Mezrich JD, Haller GW, Arn JS, Houser SL, Madsen JC, Sachs DH. Histocompatible miniature swine: an inbred large-animal model. Transplantation. 2003 Mar 27; 75(6):904-7.
    View in: PubMed
  194. Wu A, Yamada K, Neville DM, Awwad M, Wain JC, Shimizu A, Gojo S, Kitamura H, Colvin RB, Cooper DK, Sykes M, Sachs DH. Xenogeneic thymus transplantation in a pig-to-baboon model. Transplantation. 2003 Feb 15; 75(3):282-91.
    View in: PubMed
  195. Mathes DW, Randolph MA, Solari MG, Nazzal JA, Nielsen GP, Arn JS, Sachs DH, Lee WP. Split tolerance to a composite tissue allograft in a swine model. Transplantation. 2003 Jan 15; 75(1):25-31.
    View in: PubMed
  196. Shimada H, Germana S, Hayashi H, Sachs DH, LeGuern C. Expression of MHC class II DQ alpha/beta heterodimers from recombinant polycistronic retroviral genomes. Surg Today. 2003; 33(3):183-9.
    View in: PubMed
  197. Gleit ZL, Fuchimoto Y, Yamada K, Melendy E, Scheier-Dolberg R, Monajati L, Coburn RC, Neville DM, Sachs DH, Huang CA. Variable relationship between chimerism and tolerance after hematopoietic cell transplantation without myelosuppressive conditioning. Transplantation. 2002 Dec 15; 74(11):1535-44.
    View in: PubMed
  198. Bühler LH, Spitzer TR, Sykes M, Sachs DH, Delmonico FL, Tolkoff-Rubin N, Saidman SL, Sackstein R, McAfee S, Dey B, Colby C, Cosimi AB. Induction of kidney allograft tolerance after transient lymphohematopoietic chimerism in patients with multiple myeloma and end-stage renal disease. Transplantation. 2002 Nov 27; 74(10):1405-9.
    View in: PubMed
  199. Bagley J, Tian C, Sachs DH, Iacomini J. T cells mediate resistance to genetically modified bone marrow in lethally irradiated recipients. Transplantation. 2002 Nov 27; 74(10):1454-60.
    View in: PubMed
  200. Gleit ZL, Cameron AM, Fuchimoto Y, Melendy E, Monajati L, Coburn RC, Sachs DH, Huang CA. Persistent chimerism despite antidonor MHC in vitro responses in miniature swine following allogeneic hematopoietic cell transplantation. Transplantation. 2002 Nov 15; 74(9):1260-6.
    View in: PubMed
  201. Kumagai N, O'Neil JJ, Barth RN, LaMattina JC, Utsugi R, Moran SG, Yamamoto S, Vagefi PA, Kitamura H, Kamano C, Sachs DH, Yamada K. Vascularized islet-cell transplantation in miniature swine. I. Preparation of vascularized islet kidneys. Transplantation. 2002 Nov 15; 74(9):1223-30.
    View in: PubMed
  202. Teranishi K, Alwayn IP, Bühler L, Gollackner B, Knosalla C, Correa L, Down JD, White-Scharf ME, Sachs DH, Duthaler R, Katopodis A, Awwad M, Cooper DK. Depletion of natural anti-pig antibodies by the continuous infusion of oligosaccharides in a pig-to-baboon model. Transplant Proc. 2002 Nov; 34(7):2757-8.
    View in: PubMed
  203. Kumagai N, LaMattina JC, Kamano C, Vagefi PA, Barth RN, O'Neil JJ, Yamamoto S, Moran SG, Utsugi R, Sachs DH, Yamada K. Vascularized islet cell transplantation in miniature Swine: islet-kidney allografts correct the diabetic hyperglycemia induced by total pancreatectomy. Diabetes. 2002 Nov; 51(11):3220-8.
    View in: PubMed
  204. Bühler L, Kurilla-Mahon B, Chang Q, Abraham S, Alwayn IP, Appel JZ, Newman D, Awwad M, White-Scharf ME, Sackstein R, Sachs DH, Cooper DK, Down JD. Cryopreservation and mycophenolate therapy are detrimental to hematopoietic progenitor cells. Transplantation. 2002 Oct 27; 74(8):1159-66.
    View in: PubMed
  205. Haller GW, Lima B, Kunisaki SM, Germana S, Leguern C, Huang CA, Sachs DH. MHC alloantigens elicit secondary, but not primary, indirect in vitro proliferative responses. J Immunol. 2002 Oct 1; 169(7):3613-21.
    View in: PubMed
  206. Mapara MY, Kim YM, Wang SP, Bronson R, Sachs DH, Sykes M. Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: a critical role for host antigen-presenting cells. Blood. 2002 Sep 1; 100(5):1903-9.
    View in: PubMed
  207. Kunisaki SM, Haller GW, Shimizu A, Kitamura H, Colvin RB, Sachs DH. Autologous graft-versus-host disease in a porcine bone marrow transplant model. Transplantation. 2002 Aug 27; 74(4):465-71.
    View in: PubMed
  208. Heinz M, Huang CA, Emery DW, Giovino MA, LeGuern A, Kurilla-Mahon B, Theodore P, Arn JS, Sykes M, Mulligan R, Down JD, Sachs DH, Goodell MA. Use of CD9 expression to enrich for porcine hematopoietic progenitors. Exp Hematol. 2002 Jul; 30(7):809-15.
    View in: PubMed
  209. Mathes DW, Randolph MA, Bourget JL, Nielsen GP, Ferrera VR, Arn JS, Sachs DH, Lee WP. Recipient bone marrow engraftment in donor tissue after long-term tolerance to a composite tissue allograft. Transplantation. 2002 Jun 27; 73(12):1880-5.
    View in: PubMed
  210. Bagley J, Tian C, Sachs DH, Iacomini J. Induction of T-cell tolerance to an MHC class I alloantigen by gene therapy. Blood. 2002 Jun 15; 99(12):4394-9.
    View in: PubMed
  211. Mezrich JD, Sachs DH, Madsen JC. Combined heart and kidney transplantation: are two organs better than one? J Heart Lung Transplant. 2002 Jun; 21(6):714-6.
    View in: PubMed
  212. Shimizu A, Yamada K, Sachs DH, Colvin RB. Mechanisms of chronic renal allograft rejection. II. Progressive allograft glomerulopathy in miniature swine. Lab Invest. 2002 Jun; 82(6):673-86.
    View in: PubMed
  213. Schmidtko J, Wang R, Wu CL, Mauiyyedi S, Harris NL, Della Pelle P, Brousaides N, Zagachin L, Ferry JA, Wang F, Kawai T, Sachs DH, Cosimi BA, Colvin RB. Posttransplant lymphoproliferative disorder associated with an Epstein-Barr-related virus in cynomolgus monkeys. Transplantation. 2002 May 15; 73(9):1431-9.
    View in: PubMed
  214. Shimizu A, Yamada K, Sachs DH, Colvin RB. Persistent rejection of peritubular capillaries and tubules is associated with progressive interstitial fibrosis. Kidney Int. 2002 May; 61(5):1867-79.
    View in: PubMed
  215. Mueller NJ, Barth RN, Yamamoto S, Kitamura H, Patience C, Yamada K, Cooper DK, Sachs DH, Kaur A, Fishman JA. Activation of cytomegalovirus in pig-to-primate organ xenotransplantation. J Virol. 2002 May; 76(10):4734-40.
    View in: PubMed
  216. Goltz M, Ericsson T, Patience C, Huang CA, Noack S, Sachs DH, Ehlers B. Sequence analysis of the genome of porcine lymphotropic herpesvirus 1 and gene expression during posttransplant lymphoproliferative disease of pigs. Virology. 2002 Mar 15; 294(2):383-93.
    View in: PubMed
  217. LaMattina JC, Kumagai N, Barth RN, Yamamoto S, Kitamura H, Moran SG, Mezrich JD, Sachs DH, Yamada K. Vascularized thymic lobe transplantation in miniature swine: I. Vascularized thymic lobe allografts support thymopoiesis. Transplantation. 2002 Mar 15; 73(5):826-31.
    View in: PubMed
  218. McMorrow IM, Buhler L, Treter S, Neethling FA, Alwayn IP, Comrack CA, Kitamura H, Awwad M, DerSimonian H, Cooper DK, Sachs DH, LeGuern C. Modulation of the in vivo primate anti-Gal response through administration of anti-idiotypic antibodies. Xenotransplantation. 2002 Mar; 9(2):106-14.
    View in: PubMed
  219. Allan JS, Wain JC, Schwarze ML, Houser SL, Benjamin LC, Madsen JC, Sachs DH. Modeling chronic lung allograft rejection in miniature swine. Transplantation. 2002 Feb 15; 73(3):447-53.
    View in: PubMed
  220. Bühler L, Awwad M, Treter S, Chang Q, Basker M, Alwayn IP, Teranishi K, Ericsson T, Moran K, Harper D, Kurilla-Mahon B, Huang CA, Sackstein R, Sykes M, White-Scharf ME, Sachs DH, Down JD, Cooper DK. Pig hematopoietic cell chimerism in baboons conditioned with a nonmyeloablative regimen and CD154 blockade. Transplantation. 2002 Jan 15; 73(1):12-22.
    View in: PubMed
  221. Teranishi K, Gollackner B, Bühler L, Knosalla C, Correa L, Down JD, White-Scharf ME, Sachs DH, Awwad M, Cooper DK. Depletion of anti-gal antibodies in baboons by intravenous therapy with bovine serum albumin conjugated to gal oligosaccharides. Transplantation. 2002 Jan 15; 73(1):129-39.
    View in: PubMed
  222. McMorrow IM, Narayan K, Sachs DH, LeGuern C. New intra-renal graft genes associated with tolerance or rejection. Kidney Int. 2002 Jan; 61(1 Suppl):S85-93.
    View in: PubMed
  223. Bühler L, Deng S, O'Neil J, Kitamura H, Koulmanda M, Baldi A, Rahier J, Alwayn IP, Appel JZ, Awwad M, Sachs DH, Weir G, Squifflet JP, Cooper DK, Morel P. Adult porcine islet transplantation in baboons treated with conventional immunosuppression or a non-myeloablative regimen and CD154 blockade. Xenotransplantation. 2002 Jan; 9(1):3-13.
    View in: PubMed
  224. Cooper DK, Gollackner B, Sachs DH. Will the pig solve the transplantation backlog? Annu Rev Med. 2002; 53:133-47.
    View in: PubMed
  225. Bühler L, Yamada K, Kitamura H, Alwayn IP, Basker M, Appel JZ, Colvin RB, White-Scharf ME, Sachs DH, Robson SC, Awwad M, Cooper DK. Pig kidney transplantation in baboons: anti-Gal(alpha)1-3Gal IgM alone is associated with acute humoral xenograft rejection and disseminated intravascular coagulation. Transplantation. 2001 Dec 15; 72(11):1743-52.
    View in: PubMed
  226. Bühler L, Alwayn IP, Basker M, Oravec G, Thall A, White-Scharf ME, Sachs DH, Awwad M, Cooper DK. CD40-CD154 pathway blockade requires host macrophages to induce humoral unresponsiveness to pig hematopoietic cells in baboons. Transplantation. 2001 Dec 15; 72(11):1759-68.
    View in: PubMed
  227. Rodriguez-Barbosa JI, Zhao Y, Barth R, Zhao G, Arn JS, Sachs DH, Sykes M. Enhanced CD4 reconstitution by grafting neonatal porcine tissue in alternative locations is associated with donor-specific tolerance and suppression of preexisting xenoreactive T cells. Transplantation. 2001 Oct 15; 72(7):1223-31.
    View in: PubMed
  228. Basker M, Alwayn IP, Buhler L, Harper D, Abraham S, Kruger Gray H, DeAngelis H, Awwad M, Down J, Rieben R, White-Scharf ME, Sachs DH, Thall A, Cooper DK. Clearance of mobilized porcine peripheral blood progenitor cells is delayed by depletion of the phagocytic reticuloendothelial system in baboons. Transplantation. 2001 Oct 15; 72(7):1278-85.
    View in: PubMed
  229. Baron C, McMorrow I, Sachs DH, LeGuern C. Persistence of dominant T cell clones in accepted solid organ transplants. J Immunol. 2001 Oct 15; 167(8):4154-60.
    View in: PubMed
  230. Gargollo P, Yamada K, Esnaola N, Fuchimoto Y, Newell KL, Sachs DH, Huang CA. Neuropathy in miniature swine after administration of the mutant diphtheria toxin-based immunotoxin, pCD3-CRM9. Transplantation. 2001 Sep 15; 72(5):818-22.
    View in: PubMed
  231. Kunisaki SM, Haller GW, Fuchimoto Y, Huang CA, Sachs DH. Peripheral regulation of graft-versus-host alloreactivity in mixed chimeric miniature swine. Transplantation. 2001 Aug 15; 72(3):523-6.
    View in: PubMed
  232. Alwayn IP, Xu Y, Basker M, Wu C, Buhler L, Lambrigts D, Treter S, Harper D, Kitamura H, Vitetta ES, Abraham S, Awwad M, White-Scharf ME, Sachs DH, Thall A, Cooper DK. Effects of specific anti-B and/or anti-plasma cell immunotherapy on antibody production in baboons: depletion of CD20- and CD22-positive B cells does not result in significantly decreased production of anti-alphaGal antibody. Xenotransplantation. 2001 Aug; 8(3):157-71.
    View in: PubMed
  233. Kawai T, Sogawa H, Koulmanda M, Smith RN, O'Neil JJ, Wee SL, Boskovic S, Sykes M, Colvin RB, Sachs DH, Auchincloss H, Cosimi AB, C Ko DS. Long-term islet allograft function in the absence of chronic immunosuppression: a case report of a nonhuman primate previously made tolerant to a renal allograft from the same donor. Transplantation. 2001 Jul 27; 72(2):351-4.
    View in: PubMed
  234. Fuchimoto Y, Gleit ZL, Huang CA, Kitamura H, Schwarze ML, Menard MT, Mawulawde K, Madsen JC, Sachs DH. Skin-specific alloantigens in miniature swine. Transplantation. 2001 Jul 15; 72(1):122-6.
    View in: PubMed
  235. Marghoob AA, Blum R, Nossa R, Busam KJ, Sachs D, Halpern A. Agminated atypical (dysplastic) nevi: case report and review of the literature. Arch Dermatol. 2001 Jul; 137(7):917-20.
    View in: PubMed
  236. Bühler L, Goepfert C, Kitamura H, Basker M, Gojo S, Alwayn IP, Chang Q, Down JD, Tsai H, Wise R, Sachs DH, Cooper DK, Robson SC, Sackstein R. Porcine hematopoietic cell xenotransplantation in nonhuman primates is complicated by thrombotic microangiopathy. Bone Marrow Transplant. 2001 Jun; 27(12):1227-36.
    View in: PubMed
  237. Brander C, Matter-Reissmann UB, Jones NG, Walker BD, Sachs DH, Seebach JD. Inhibition of human NK cell-mediated cytotoxicity by exposure to ammonium chloride. J Immunol Methods. 2001 Jun 1; 252(1-2):1-14.
    View in: PubMed
  238. Sykes M, Sachs DH. Mixed chimerism. Philos Trans R Soc Lond B Biol Sci. 2001 May 29; 356(1409):707-26.
    View in: PubMed
  239. Utsugi R, Barth RN, Lee RS, Kitamura H, LaMattina JC, Ambroz J, Sachs DH, Yamada K. Induction of transplantation tolerance with a short course of tacrolimus (FK506): I. Rapid and stable tolerance to two-haplotype fully mhc-mismatched kidney allografts in miniature swine. Transplantation. 2001 May 27; 71(10):1368-79.
    View in: PubMed
  240. Lee WP, Rubin JP, Bourget JL, Cober SR, Randolph MA, Nielsen GP, Ierino FL, Sachs DH. Tolerance to limb tissue allografts between swine matched for major histocompatibility complex antigens. Plast Reconstr Surg. 2001 May; 107(6):1482-90; discussion 1491-2.
    View in: PubMed
  241. Bourget JL, Mathes DW, Nielsen GP, Randolph MA, Tanabe YN, Ferrara VR, Wu A, Arn S, Sachs DH, Lee WP. Tolerance to musculoskeletal allografts with transient lymphocyte chimerism in miniature swine. Transplantation. 2001 Apr 15; 71(7):851-6.
    View in: PubMed
  242. Huang CA, Fuchimoto Y, Gleit ZL, Ericsson T, Griesemer A, Scheier-Dolberg R, Melendy E, Kitamura H, Fishman JA, Ferry JA, Harris NL, Patience C, Sachs DH. Posttransplantation lymphoproliferative disease in miniature swine after allogeneic hematopoietic cell transplantation: similarity to human PTLD and association with a porcine gammaherpesvirus. Blood. 2001 Mar 1; 97(5):1467-73.
    View in: PubMed
  243. Baron C, Sachs DH, LeGuern C. A particular TCR beta variable region used by T cells infiltrating kidney transplants. J Immunol. 2001 Feb 15; 166(4):2589-96.
    View in: PubMed
  244. Rubin JP, Cober SR, Butler PE, Randolph MA, Gazelle GS, Ierino FL, Sachs DH, Lee WP. Injection of allogeneic bone marrow cells into the portal vein of swine in utero. J Surg Res. 2001 Feb; 95(2):188-94.
    View in: PubMed
  245. Seebach JD, Schneider MK, Comrack CA, LeGuern A, Kolb SA, Knolle PA, Germana S, DerSimonian H, LeGuern C, Sachs DH. Immortalized bone-marrow derived pig endothelial cells. Xenotransplantation. 2001 Feb; 8(1):48-61.
    View in: PubMed
  246. Schwarze ML, Mezrich JD, Menard MT, Houser SL, Maloney ME, Pillsbury EP, Sachs DH, Madsen JC. The effects of mycophenolate mofetil on cardiac allograft survival and cardiac allograft vasculopathy in miniature swine. J Heart Lung Transplant. 2001 Feb; 20(2):160.
    View in: PubMed
  247. Mezrich JD, Yamada K, Lee RS, Mawulawde K, Houser SL, Schwarze ML, Maloney ME, Amoah HC, Pillsbury EP, Sachs DH, Madsen JC. Mechanisms of tolerance induction in the heart/kidney model in miniature swine. J Heart Lung Transplant. 2001 Feb; 20(2):172-173.
    View in: PubMed
  248. Fuchimoto Y, Huang CA, Yamada K, Gleit ZL, Kitamura H, Griesemer A, Scheier-Dolberg R, Melendy E, White-Scharf ME, Sachs DH. Induction of kidney allograft tolerance through mixed chimerism in miniature swine. Transplant Proc. 2001 Feb-Mar; 33(1-2):77.
    View in: PubMed
  249. Wu A, Ierino FL, Yamada K, Sachs DH. Specific suppression of proliferative responses by primed lymphocytes of tolerant miniature swine. Transplant Proc. 2001 Feb-Mar; 33(1-2):87.
    View in: PubMed
  250. Lee RS, Rusche JR, Maloney ME, Sachs DH, Sayegh MH, Madsen JC. CTLA4Ig-induced linked regulation of allogeneic T cell responses. Transplant Proc. 2001 Feb-Mar; 33(1-2):88-9.
    View in: PubMed
  251. Mathes DW, Yamada K, Randolph MA, Utsugi R, Solari MG, Gazelle GS, Wu A, Sachs DH, Lee WP. In utero induction of transplantation tolerance. Transplant Proc. 2001 Feb-Mar; 33(1-2):98-100.
    View in: PubMed
  252. Utsugi R, Barth RN, Kitamura H, Ambroz J, Sachs DH, Yamada K. Tolerance across a two-haplotype, fully MHC-mismatched barrier induced in miniature swine renal allografts treated with a 12-day course of tacrolimus. Transplant Proc. 2001 Feb-Mar; 33(1-2):101.
    View in: PubMed
  253. Sogawa H, Kawai T, Wee SL, Boskovic S, Nadazdin O, Phelan J, Abrahamian G, Ko DS, Hong H, Mauiyyedi S, Colvin RB, Sachs DH, Cosimi AB. Comparison of horse antithymocyte globulin with other T cell-depleting antibodies for induction of chimerism and renal allograft tolerance in nonhuman primates. Transplant Proc. 2001 Feb-Mar; 33(1-2):116-7.
    View in: PubMed
  254. Kawai T, Abrahamian G, Sogawa H, Wee S, Boskovic S, Andrew D, Nadazdin O, Mauiyyedi S, Weymouth D, Ko D, Colvin R, Sachs D, Cosimi A. Costimulatory blockade for induction of mixed chimerism and renal allograft tolerance in nonhuman primates. Transplant Proc. 2001 Feb-Mar; 33(1-2):221-2.
    View in: PubMed
  255. Allan JS, Wain JC, Schwarze ML, Houser SL, Madsen JC, Sachs DH. Obliterative bronchiolitis develops in miniature swine transplanted across a minor histocompatibility barrier. Transplant Proc. 2001 Feb-Mar; 33(1-2):358-9.
    View in: PubMed
  256. Mathes DW, Bourget JL, Randolph MA, Solari MG, Wu A, Sachs DH, Lee WP. Tolerance to vascularized musculoskeletal allografts. Transplant Proc. 2001 Feb-Mar; 33(1-2):616-7.
    View in: PubMed
  257. Lee RS, Rusche JR, Maloney ME, Sachs DH, Sayegh MH, Madsen JC. CTLA4Ig-induced linked regulation of allogeneic T cell responses. J Immunol. 2001 Feb 1; 166(3):1572-82.
    View in: PubMed
  258. Wu A, Yamada K, Awwad M, Kitamura H, Wain J, Neville DM, Cooper DK, Sykes M, Sachs DH. Effects of xenogeneic thymic transplantation in baboons. Transplant Proc. 2001 Feb-Mar; 33(1-2):766.
    View in: PubMed
  259. Bühler L, Yamada K, Alwayn I, Kitamura H, Basker M, Barth RN, Appel J, Awwad M, Thall A, White-Scharf ME, Sachs DH, Cooper DK. Miniature swine and hDAF pig kidney transplantation in baboons treated with a nonmyeloablative regimen and CD154 blockade. Transplant Proc. 2001 Feb-Mar; 33(1-2):716.
    View in: PubMed
  260. Fuchimoto Y, Huang CA, Gleit ZL, Kitamura H, Griesemer A, Melendy E, Scheier-Dolberg R, White-Scharf ME, Sachs DH. Mixed chimerism using a nonmyelosuppressive regimen in miniature swine. Transplant Proc. 2001 Feb-Mar; 33(1-2):118-9.
    View in: PubMed
  261. Teranishi K, Gollackner B, Buhler L, Knosalla C, Sachs DH, Awwad M, Cooper DK. Total depletion and suppression of natural and induced anti-pig antibodies in baboons. J Heart Lung Transplant. 2001 Feb; 20(2):214.
    View in: PubMed
  262. Sachs DH, Sykes M, Robson SC, Cooper DK. Xenotransplantation. Adv Immunol. 2001; 79:129-223.
    View in: PubMed
  263. Sonntag KC, Emery DW, Yasumoto A, Haller G, Germana S, Sablinski T, Shimizu A, Yamada K, Shimada H, Arn S, Sachs DH, LeGuern C. Tolerance to solid organ transplants through transfer of MHC class II genes. J Clin Invest. 2001 Jan; 107(1):65-71.
    View in: PubMed
  264. Dey BR, McAfee S, Sackstein R, Colby C, Saidman S, Weymouth D, Poliquin C, Vanderklish J, Sachs DH, Sykes M, Spitzer TR. Successful allogeneic stem cell transplantation with nonmyeloablative conditioning in patients with relapsed hematologic malignancy following autologous stem cell transplantation. Biol Blood Marrow Transplant. 2001; 7(11):604-12.
    View in: PubMed
  265. Shimizu A, Yamada K, Sachs DH, Colvin RB. Intragraft events preceding chronic renal allograft rejection in a modified tolerance protocol. Kidney Int. 2000 Dec; 58(6):2546-58.
    View in: PubMed
  266. Shimizu A, Yamada K, Meehan SM, Sachs DH, Colvin RB. Acceptance reaction: intragraft events associated with tolerance to renal allografts in miniature swine. J Am Soc Nephrol. 2000 Dec; 11(12):2371-80.
    View in: PubMed
  267. Bühler L, Basker M, Alwayn IP, Goepfert C, Kitamura H, Kawai T, Gojo S, Kozlowski T, Ierino FL, Awwad M, Sachs DH, Sackstein R, Robson SC, Cooper DK. Coagulation and thrombotic disorders associated with pig organ and hematopoietic cell transplantation in nonhuman primates. Transplantation. 2000 Nov 15; 70(9):1323-31.
    View in: PubMed
  268. Bagley J, Wu Y, Sachs DH, Iacomini J. Defining the requirements for peptide recognition in gene therapy-induced T cell tolerance. J Immunol. 2000 Nov 1; 165(9):4842-7.
    View in: PubMed
  269. Sonntag KC, Nebhard N, Haller GW, Yasumoto A, Sachs DH, LeGuern C. Assessment of transduction rates of porcine bone marrow. J Hematother Stem Cell Res. 2000 Oct; 9(5):721-6.
    View in: PubMed
  270. Sonntag KC, Haller GW, Giauffret D, Germana S, Reeves SA, Levy J, Sachs DH, LeGuern C. Regulated expression of an MHC class II gene from a promoter-inducible retrovirus. Hum Gene Ther. 2000 Sep 20; 11(14):1961-9.
    View in: PubMed
  271. Basker M, Alwayn IP, Treter S, Harper D, Buhler L, Andrews D, Thall A, Lambrigts D, Awwad M, White-Scharf M, Sachs DH, Cooper DK. Effect of B cell/plasma cell depletion or suppression on anti-Gal antibody in the baboon. Transplant Proc. 2000 Aug; 32(5):1009.
    View in: PubMed
  272. Alwayn IP, Buhler L, Basker M, Goepfert C, Kawai T, Kozlowski T, Ierino F, Sachs DH, Sackstein R, Robson SC, Cooper DK. Coagulation/thrombotic disorders associated with organ and cell xenotransplantation. Transplant Proc. 2000 Aug; 32(5):1099.
    View in: PubMed
  273. Bühler L, Awwad M, Treter S, Basker M, Ericson T, Lachance A, Oldmixon B, Kurilla-Mahon B, Gojo S, Huang C, Thall A, Down JD, White-Scharf ME, Sachs DH, Cooper DK. Induction of mixed hematopoietic chimerism in the pig-to-baboon model. Transplant Proc. 2000 Aug; 32(5):1101.
    View in: PubMed
  274. Bühler L, Treter S, McMorrow I, Neethling FA, Alwayn I, Awwad M, Thall A, Cooper DK, LeGuern C, Sachs DH. Injection of porcine anti-idiotypic antibodies to primate anti-Gal antibodies leads to active inhibition of serum cytotoxicity in a baboon. Transplant Proc. 2000 Aug; 32(5):1102.
    View in: PubMed
  275. Gopfert C, Buhler L, Wise R, Basker M, Gojo S, Imai M, Alwayn I, Sachs DH, Sackstein R, Cooper DK, Robson SC. Von willebrand factor concentration, multimeric patterns, and cleaving protease activity in baboons undergoing xenogeneic peripheral blood stem cell transplantation. Transplant Proc. 2000 Aug; 32(5):990.
    View in: PubMed
  276. Salmon H, Johnson I, Germana S, Haller GW, Sachs DH, Leguern C. Dendritic cells enriched from swine thymus co-express CD1, CD2 and major histocompatibility complex class II and actively stimulate alloreactive T lymphocytes. Scand J Immunol. 2000 Aug; 52(2):164-72.
    View in: PubMed
  277. Wu A, Yamada K, Awwad M, Shimizu A, Watts A, Murphy M, Gojo S, Neville D, Cooper DK, Sykes M, Sachs DH. Experience with porcine thymic transplantation in baboons. Transplant Proc. 2000 Aug; 32(5):1048.
    View in: PubMed
  278. Abe M, Chen AM, Qi J, Sachs DH, Sykes M, Yang Y. Porcine stem cell factor facilitates long-lasting porcine hematopoietic engraftment in murine recipients. Transplant Proc. 2000 Aug; 32(5):1047.
    View in: PubMed
  279. Watts A, Foley A, Awwad M, Treter S, Oravec G, Buhler L, Alwayn IP, Kozlowski T, Lambrigts D, Gojo S, Basker M, White-Scharf ME, Andrews D, Sachs DH, Cooper DK. Plasma perfusion by apheresis through a Gal immunoaffinity column successfully depletes anti-Gal antibody: experience with 320 aphereses in baboons. Xenotransplantation. 2000 Aug; 7(3):181-5.
    View in: PubMed
  280. Down JD, Awwad M, Kurilla-Mahon B, Moran K, Ericsson T, Oldmixon B, Lachance A, Watts A, Treter S, Nash K, Gojo S, Sachs DH, White-Scharf ME, Cooper DK. Increases in autologous hematopoietic progenitors in the blood of baboons following irradiation and treatment with porcine stem cell factor and interleukin-3. Transplant Proc. 2000 Aug; 32(5):1045-6.
    View in: PubMed
  281. Bühler L, Awwad M, Basker M, Gojo S, Thall A, Down JD, Sykes M, Andrews D, Sackstein R, White-Scharf ME, Sachs DH, Cooper DK. A nonmyeloablative regimen with CD40L blockade leads to humoral and cellular hyporesponsiveness to pig hematopoietic cells in baboons. Transplant Proc. 2000 Aug; 32(5):1100.
    View in: PubMed
  282. Watts A, Foley A, Awwad M, Treter S, Lambrigts D, Buhler L, Gojo S, Basker M, Oravec G, Sachs DH, Andrews D, Cooper DK. Plasma perfusion by apheresis through a gal immunoaffinity column successfully depletes anti-Gal antibody: experience with 275 aphereses in baboons. Transplant Proc. 2000 Aug; 32(5):860.
    View in: PubMed
  283. Kawai T, Wee SL, Bazin H, Latinne D, Phelan J, Boskovic S, Ko DS, Hong HZ, Mauiyyedi S, Nadazdin O, Abrahamian G, Preffer F, Colvin RB, Sachs DH, Cosimi AB. Association of natural killer cell depletion with induction of mixed chimerism and allograft tolerance in non-human primates. Transplantation. 2000 Jul 27; 70(2):368-74.
    View in: PubMed
  284. Schwarze ML, Menard MT, Fuchimoto Y, Huang CA, Houser S, Mawulawde K, Allison KS, Sachs DH, Madsen JC. Mixed hematopoietic chimerism induces long-term tolerance to cardiac allografts in miniature swine. Ann Thorac Surg. 2000 Jul; 70(1):131-8; discussion 138-9.
    View in: PubMed
  285. Chen AM, Zhou Y, Swenson K, Sachs DH, Sykes M, Yang YG. Porcine stem cell engraftment and seeding of murine thymus with class II+ cells in mice expressing porcine cytokines: toward tolerance induction across discordant xenogeneic barriers. Transplantation. 2000 Jun 27; 69(12):2484-90.
    View in: PubMed
  286. Bühler L, Awwad M, Basker M, Gojo S, Watts A, Treter S, Nash K, Oravec G, Chang Q, Thall A, Down JD, Sykes M, Andrews D, Sackstein R, White-Scharf ME, Sachs DH, Cooper DK. High-dose porcine hematopoietic cell transplantation combined with CD40 ligand blockade in baboons prevents an induced anti-pig humoral response. Transplantation. 2000 Jun 15; 69(11):2296-304.
    View in: PubMed
  287. Shimizu A, Meehan SM, Kozlowski T, Sablinski T, Ierino FL, Cooper DK, Sachs DH, Colvin RB. Acute humoral xenograft rejection: destruction of the microvascular capillary endothelium in pig-to-nonhuman primate renal grafts. Lab Invest. 2000 Jun; 80(6):815-30.
    View in: PubMed
  288. Fuchimoto Y, Huang CA, Yamada K, Shimizu A, Kitamura H, Colvin RB, Ferrara V, Murphy MC, Sykes M, White-Scharf M, Neville DM, Sachs DH. Mixed chimerism and tolerance without whole body irradiation in a large animal model. J Clin Invest. 2000 Jun; 105(12):1779-89.
    View in: PubMed
  289. Zhao Y, Rodriguez-Barbosa JI, Swenson K, Barth RN, Shimizu A, Arn JS, Sachs DH, Sykes M. The induction of specific pig skin graft tolerance by grafting with neonatal pig thymus in thymectomized mice. Transplantation. 2000 Apr 15; 69(7):1447-51.
    View in: PubMed
  290. Sachs DH. Mixed chimerism as an approach to transplantation tolerance. Clin Immunol. 2000 Apr; 95(1 Pt 2):S63-8.
    View in: PubMed
  291. Yamada K, Mawulawde K, Menard MT, Shimizu A, Aretz HT, Choo JK, Allison KS, Slisz JK, Sachs DH, Madsen JC. Mechanisms of tolerance induction and prevention of cardiac allograft vasculopathy in miniature swine: the effect of augmentation of donor antigen load. J Thorac Cardiovasc Surg. 2000 Apr; 119(4 Pt 1):709-19.
    View in: PubMed
  292. Yamada K, Shimizu A, Utsugi R, Ierino FL, Gargollo P, Haller GW, Colvin RB, Sachs DH. Thymic transplantation in miniature swine. II. Induction of tolerance by transplantation of composite thymokidneys to thymectomized recipients. J Immunol. 2000 Mar 15; 164(6):3079-86.
    View in: PubMed
  293. Lee RS, Yamada K, Womer KL, Pillsbury EP, Allison KS, Marolewski AE, Geng D, Thall AD, Arn JS, Sachs DH, Sayegh MH, Madsen JC. Blockade of CD28-B7, but not CD40-CD154, prevents costimulation of allogeneic porcine and xenogeneic human anti-porcine T cell responses. J Immunol. 2000 Mar 15; 164(6):3434-44.
    View in: PubMed
  294. Sachs DH, Bonner-Weir S. New islets from old. Nat Med. 2000 Mar; 6(3):250-1.
    View in: PubMed
  295. Hartig CV, Haller GW, Sachs DH, Kuhlenschmidt S, Heeger PS. Naturally developing memory T cell xenoreactivity to swine antigens in human peripheral blood lymphocytes. J Immunol. 2000 Mar 1; 164(5):2790-6.
    View in: PubMed
  296. Gojo S, Shimizu A, Ierino FL, Banerjee PT, Cooper DK, LeGuern C, Sachs DH. Xenogeneic and allogeneic skin grafting after retrovirus-mediated SLA class II DR gene transfer in baboons. Transplant Proc. 2000 Mar; 32(2):289-90.
    View in: PubMed
  297. Warrens AN, Simon AR, Theodore PR, Sachs DH, Sykes M. Cross-species compatibility of intercellular adhesion molecule-1 (CD54) with its ligands. Transplantation. 2000 Feb 15; 69(3):394-9.
    View in: PubMed
  298. Kawai T, Andrews D, Colvin RB, Sachs DH, Cosimi AB. Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand Nat Med. 2000 Feb; 6(2):114.
    View in: PubMed
  299. Kawai T, Andrews D, Colvin RB, Sachs DH, Cosimi AB. Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand. Nat Med. 2000 Feb; 6(2):114.
    View in: PubMed
  300. Yang YG, Chen AM, Garrett LJ, Sergio JJ, Theodore P, Awwad M, VerHalen J, Bodine DM, Sachs DH, Sykes M. Development and analysis of transgenic mice expressing porcine hematopoietic cytokines: a model for achieving durable porcine hematopoietic chimerism across an extensive xenogeneic barrier. Xenotransplantation. 2000 Feb; 7(1):58-64.
    View in: PubMed
  301. Colby C, Chang Q, Fuchimoto Y, Ferrara V, Murphy M, Sackstein R, Spitzer TR, White-Scharf ME, Sachs DH. Cytokine-mobilized peripheral blood progenitor cells for allogeneic reconstitution of miniature swine. Transplantation. 2000 Jan 15; 69(1):135-40.
    View in: PubMed
  302. Kozlowski T, Sablinski T, Basker M, Kitamura H, Spitzer TR, Fishman J, Sykes M, Cooper DK, Sachs DH. Decreased graft-versus-host disease after haplotype mismatched bone marrow allografts in miniature swine following interleukin-2 treatment. Bone Marrow Transplant. 2000 Jan; 25(1):47-52.
    View in: PubMed
  303. Spitzer TR, McAfee S, Sackstein R, Colby C, Toh HC, Multani P, Saidman S, Weyouth DW, Preffer F, Poliquin C, Foley A, Cox B, Andrews D, Sachs DH, Sykes M. Intentional induction of mixed chimerism and achievement of antitumor responses after nonmyeloablative conditioning therapy and HLA-matched donor bone marrow transplantation for refractory hematologic malignancies. Biol Blood Marrow Transplant. 2000; 6(3A):309-20.
    View in: PubMed
  304. Huang CA, Fuchimoto Y, Scheier-Dolberg R, Murphy MC, Neville DM, Sachs DH. Stable mixed chimerism and tolerance using a nonmyeloablative preparative regimen in a large-animal model. J Clin Invest. 2000 Jan; 105(2):173-81.
    View in: PubMed
  305. Bartholomew AM, Powelson J, Sachs DH, Bailin M, Boskovic S, Colvin R, Hong HZ, Johnson M, Kimikawa M, LeGuern A, Meehan S, Sablinski T, Wee SL, Cosimi AB. Tolerance in a concordant nonhuman primate model. Transplantation. 1999 Dec 15; 68(11):1708-16.
    View in: PubMed
  306. Kawai T, Poncelet A, Sachs DH, Mauiyyedi S, Boskovic S, Wee SL, Ko DS, Bartholomew A, Kimikawa M, Hong HZ, Abrahamian G, Colvin RB, Cosimi AB. Long-term outcome and alloantibody production in a non-myeloablative regimen for induction of renal allograft tolerance. Transplantation. 1999 Dec 15; 68(11):1767-75.
    View in: PubMed
  307. Yamada K, Shimizu A, Ierino FL, Utsugi R, Barth RN, Esnaola N, Colvin RB, Sachs DH. Thymic transplantation in miniature swine. I. Development and function of the "thymokidney". Transplantation. 1999 Dec 15; 68(11):1684-92.
    View in: PubMed
  308. Nash K, Chang Q, Watts A, Treter S, Oravec G, Ferrara V, Buhler L, Basker M, Gojo S, Sachs DH, White-Scharf M, Down JD, Cooper DK. Peripheral blood progenitor cell mobilization and leukapheresis in pigs. Lab Anim Sci. 1999 Dec; 49(6):645-9.
    View in: PubMed
  309. Haller GW, Esnaola N, Yamada K, Wu A, Shimizu A, Hansen A, Ferrara VR, Allison KS, Colvin RB, Sykes M, Sachs DH. Thymic transplantation across an MHC class I barrier in swine. J Immunol. 1999 Oct 1; 163(7):3785-92.
    View in: PubMed
  310. Kawai T, Sachs DH, Cosimi AB. Tolerance to vascularized organ allografts in large-animal models. Curr Opin Immunol. 1999 Oct; 11(5):516-20.
    View in: PubMed
  311. Huang CA, Yamada K, Murphy MC, Shimizu A, Colvin RB, Neville DM, Sachs DH. In vivo T cell depletion in miniature swine using the swine CD3 immunotoxin, pCD3-CRM9. Transplantation. 1999 Sep 27; 68(6):855-60.
    View in: PubMed
  312. Shimada H, Germana S, Sonntag KC, Banerjee P, Moore D, Sachs DH, LeGuern C. MHC class II alpha/beta heterodimeric cell surface molecules expressed from a single proviral genome. Hum Gene Ther. 1999 Sep 20; 10(14):2397-405.
    View in: PubMed
  313. Flye MW, Pennington L, Kirkman R, Weber B, Sindelar W, Sachs DH. Spontaneous acceptance or rejection of orthotopic liver transplants in outbred and partially inbred miniature swine. Transplantation. 1999 Sep 15; 68(5):599-607.
    View in: PubMed
  314. Yamada K, Choo JK, Allan JS, Erhorn AE, Menard MT, Mawulawde K, Slisz JK, Aretz HT, Shimizu A, Sachs DH, Madsen JC. The effect of thymectomy on tolerance induction and cardiac allograft vasculopathy in a miniature swine heart/kidney transplantation model. Transplantation. 1999 Aug 27; 68(4):485-91.
    View in: PubMed
  315. Spitzer TR, Delmonico F, Tolkoff-Rubin N, McAfee S, Sackstein R, Saidman S, Colby C, Sykes M, Sachs DH, Cosimi AB. Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: the induction of allograft tolerance through mixed lymphohematopoietic chimerism. Transplantation. 1999 Aug 27; 68(4):480-4.
    View in: PubMed
  316. Emery DW, Holley K, Sachs DH. Enhancement of swine progenitor chimerism in mixed swine/human bone marrow cultures with swine cytokines. Exp Hematol. 1999 Aug; 27(8):1330-7.
    View in: PubMed
  317. Huang CA, Lorf T, Arn JS, Koo GC, Blake T, Sachs DH. Characterization of a monoclonal anti-porcine CD3 antibody. Xenotransplantation. 1999 Aug; 6(3):201-12.
    View in: PubMed
  318. Fuchimoto Y, Huang C, Shimizu A, Seebach J, Arn S, Sachs DH. An allelic non-histocompatibility antigen with wide tissue distribution as a marker for chimerism in pigs. Tissue Antigens. 1999 Jul; 54(1):43-52.
    View in: PubMed
  319. Seebach JD, Pazmany L, Waneck GL, Minja F, Germana S, LeGuern C, Sachs DH. HLA-G expression on porcine endothelial cells protects partially against direct human NK cytotoxicity but not against ADCC. Transplant Proc. 1999 Jun; 31(4):1864-5.
    View in: PubMed
  320. Sykes M, Preffer F, McAfee S, Saidman SL, Weymouth D, Andrews DM, Colby C, Sackstein R, Sachs DH, Spitzer TR. Mixed lymphohaemopoietic chimerism and graft-versus-lymphoma effects after non-myeloablative therapy and HLA-mismatched bone-marrow transplantation. Lancet. 1999 May 22; 353(9166):1755-9.
    View in: PubMed
  321. Fuchimoto Y, Yamada K, Shimizu A, Yasumoto A, Sawada T, Huang CH, Sachs DH. Relationship between chimerism and tolerance in a kidney transplantation model. J Immunol. 1999 May 15; 162(10):5704-11.
    View in: PubMed
  322. Friedman T, Shimizu A, Smith RN, Colvin RB, Seebach JD, Sachs DH, Iacomini J. Human CD4+ T cells mediate rejection of porcine xenografts. J Immunol. 1999 May 1; 162(9):5256-62.
    View in: PubMed
  323. Yamada K, Ierino FL, Gianello PR, Shimizu A, Colvin RB, Sachs DH. Role of the thymus in transplantation tolerance in miniature swine. III. Surgical manipulation of the thymus interferes with stable induction of tolerance to class I-mismatched renal allografts. Transplantation. 1999 Apr 27; 67(8):1112-9.
    View in: PubMed
  324. Ierino FL, Gojo S, Banerjee PT, Giovino M, Xu Y, Gere J, Kaynor C, Awwad M, Monroy R, Rembert J, Hatch T, Foley A, Kozlowski T, Yamada K, Neethling FA, Fishman J, Bailin M, Spitzer TR, Cooper DK, Cosimi AB, LeGuern C, Sachs DH. Transfer of swine major histocompatibility complex class II genes into autologous bone marrow cells of baboons for the induction of tolerance across xenogeneic barriers. Transplantation. 1999 Apr 27; 67(8):1119-28.
    View in: PubMed
  325. Sablinski T, Emery DW, Monroy R, Hawley RJ, Xu Y, Gianello P, Lorf T, Kozlowski T, Bailin M, Cooper DK, Cosimi AB, Sachs DH. Long-term discordant xenogeneic (porcine-to-primate) bone marrow engraftment in a monkey treated with porcine-specific growth factors. Transplantation. 1999 Apr 15; 67(7):972-7.
    View in: PubMed
  326. van Gorder MA, Della Pelle P, Henson JW, Sachs DH, Cosimi AB, Colvin RB. Cynomolgus polyoma virus infection: a new member of the polyoma virus family causes interstitial nephritis, ureteritis, and enteritis in immunosuppressed cynomolgus monkeys. Am J Pathol. 1999 Apr; 154(4):1273-84.
    View in: PubMed
  327. Nikolic B, Gardner JP, Scadden DT, Arn JS, Sachs DH, Sykes M. Normal development in porcine thymus grafts and specific tolerance of human T cells to porcine donor MHC. J Immunol. 1999 Mar 15; 162(6):3402-7.
    View in: PubMed
  328. Sachs DH. Immunologic tolerance to organ transplants. J Gastrointest Surg. 1999 Mar-Apr; 3(2):105-10.
    View in: PubMed
  329. Yamada K, Gianello PR, Ierino FL, Fishbein J, Lorf T, Shimizu A, Colvin RB, Sachs DH. Role of the thymus in transplantation tolerance in miniature swine: II. Effect of steroids and age on the induction of tolerance to class I mismatched renal allografts. Transplantation. 1999 Feb 15; 67(3):458-67.
    View in: PubMed
  330. Yamada K, Menard MT, Mawulawde K, Slisz JK, Choo JK, Erhorn AE, Sachs DH, Madsen JC. The effects of heart/kidney versus double heart transplantation on tolerance induction and prevention of cardiac allograft vasculopathy. Transplant Proc. 1999 Feb-Mar; 31(1-2):108.
    View in: PubMed
  331. Chae SJ, Kramer AD, Zhao Y, Arn S, Cooper DK, Sachs DH. Lack of variation in alphaGal expression on lymphocytes in miniature swine of different genotypes. Xenotransplantation. 1999 Feb; 6(1):43-51.
    View in: PubMed
  332. Kozlowski T, Monroy R, Giovino M, Hawley RJ, Glaser R, Li Z, Meshulam DH, Spitzer TR, Cooper DK, Sachs DH. Effect of pig-specific cytokines on mobilization of hematopoietic progenitor cells in pigs and on pig bone marrow engraftment in baboons. Xenotransplantation. 1999 Feb; 6(1):17-27.
    View in: PubMed
  333. Sachs D. Introduction of Fritz Bach, Medawar Prize Laureate. Transplant Proc. 1999 Feb-Mar; 31(1-2):50.
    View in: PubMed
  334. Wu A, Esnaola NF, Yamada K, Awwad M, Shimizu A, Huang C, Wain J, Zhao Y, Neville DM, Cooper DK, Sykes M, Sachs DH. Xenogeneic thymic transplantation in a pig-to-nonhuman primate model. Transplant Proc. 1999 Feb-Mar; 31(1-2):957.
    View in: PubMed
  335. Yamada K, Shimizu A, Ierino FL, Gargollo P, Barth R, Colvin RB, Sachs DH. Allogeneic thymo-kidney transplants induce stable tolerance in miniature swine. Transplant Proc. 1999 Feb-Mar; 31(1-2):1199-200.
    View in: PubMed
  336. Kozlowski T, Shimizu A, Lambrigts D, Yamada K, Fuchimoto Y, Glaser R, Monroy R, Xu Y, Awwad M, Colvin RB, Cosimi AB, Robson SC, Fishman J, Spitzer TR, Cooper DK, Sachs DH. Porcine kidney and heart transplantation in baboons undergoing a tolerance induction regimen and antibody adsorption. Transplantation. 1999 Jan 15; 67(1):18-30.
    View in: PubMed
  337. Ierino FL, Yamada K, Hatch T, Rembert J, Sachs DH. Peripheral tolerance to class I mismatched renal allografts in miniature swine: donor antigen-activated peripheral blood lymphocytes from tolerant swine inhibit antidonor CTL reactivity. J Immunol. 1999 Jan 1; 162(1):550-9.
    View in: PubMed
  338. Shimada H, Alexander RC, Germana S, Sachs DH, LeGuern C. Recombinant retrovirus vectors for the expression of MHC class II heterodimers. Surg Today. 1999; 29(6):533-41.
    View in: PubMed
  339. Sachs DH. The immunology of xenotransplantation: introduction. Ann N Y Acad Sci. 1998 Dec 30; 862:1-4.
    View in: PubMed
  340. Shaikh R, Sachs D, Fishman J, Miranda B, Oborne M, Engstrom L, Kennedy I, Meslin FX. Xenotransplantation and its implications. Background information for the press. Ann N Y Acad Sci. 1998 Dec 30; 862:237-50.
    View in: PubMed
  341. Ierino FL, Kozlowski T, Siegel JB, Shimizu A, Colvin RB, Banerjee PT, Cooper DK, Cosimi AB, Bach FH, Sachs DH, Robson SC. Disseminated intravascular coagulation in association with the delayed rejection of pig-to-baboon renal xenografts. Transplantation. 1998 Dec 15; 66(11):1439-50.
    View in: PubMed
  342. Allan JS, Slisz JK, Vesga L, Arn JS, Yamada K, Sachs DH, Madsen JC. Enhanced efficacy of repeated anti-CD8 monoclonal antibody therapy by high-dose cyclosporine treatment. Transplant Proc. 1998 Dec; 30(8):4062-3.
    View in: PubMed
  343. Lambrigts D, Van Calster P, Xu Y, Awwad M, Neethling FA, Kozlowski T, Foley A, Watts A, Chae SJ, Fishman J, Thall AD, White-Scharf ME, Sachs DH, Cooper DK. Pharmacologic immunosuppressive therapy and extracorporeal immunoadsorption in the suppression of anti-alphaGal antibody in the baboon. Xenotransplantation. 1998 Nov; 5(4):274-83.
    View in: PubMed
  344. Ko DS, Bartholomew A, Poncelet AJ, Sachs DH, Huang C, LeGuern A, Abraham KI, Colvin RB, Boskovic S, Hong HZ, Wee SL, Winn HJ, Cosimi AB. Demonstration of multilineage chimerism in a nonhuman primate concordant xenograft model. Xenotransplantation. 1998 Nov; 5(4):298-304.
    View in: PubMed
  345. Emery DW, Shimada H, Germana S, Sachs DH, LeGuern C. Transfer of porcine MHC DRalpha into IEalpha-deficient murine bone marrow results in reduced IE-restricted Vbeta usage. Transplantation. 1998 Oct 27; 66(8):1081-8.
    View in: PubMed
  346. Lambrigts D, Menard MT, Alexandre GP, Franssen C, Meurisse M, Van Calster P, Coignoul F, Mawulawde K, Choo JK, Yamada K, Erhorn AE, Slisz JK, Chiotellis P, Aretz HT, Sachs DH, Madsen JC. Creation of the "thymoheart" allograft: implantation of autologous thymus into the heart prior to procurement. Transplantation. 1998 Sep 27; 66(6):810-4.
    View in: PubMed
  347. Bracy JL, Sachs DH, Iacomini J. Inhibition of xenoreactive natural antibody production by retroviral gene therapy. Science. 1998 Sep 18; 281(5384):1845-7.
    View in: PubMed
  348. Lambrigts D, Sachs DH, Cooper DK. Discordant organ xenotransplantation in primates: world experience and current status. Transplantation. 1998 Sep 15; 66(5):547-61.
    View in: PubMed
  349. Wekerle T, Sachs DH, Sykes M. Mixed chimerism for the induction of tolerance: potential applicability in clinical composite tissue grafting. Transplant Proc. 1998 Sep; 30(6):2708-10.
    View in: PubMed
  350. Lee WP, Rubin JP, Cober S, Ierino F, Randolph MA, Sachs DH. Use of swine model in transplantation of vascularized skeletal tissue allografts. Transplant Proc. 1998 Sep; 30(6):2743-5.
    View in: PubMed
  351. Choi SW, Park HY, Rubeiz NG, Sachs D, Gilchrest BA. Protein kinase C-alpha levels are inversely associated with growth rate in cultured human dermal fibroblasts. J Dermatol Sci. 1998 Sep; 18(1):54-63.
    View in: PubMed
  352. Ierino FL, Yamada K, Lorf T, Arn JS, Sachs DH. Mechanism of tolerance to class I-mismatched renal allografts in miniature swine: regulation of interleukin-2 receptor alpha-chain expression on CD8 peripheral blood lymphocytes of tolerant animals. Transplantation. 1998 Aug 27; 66(4):454-60.
    View in: PubMed
  353. Simon AR, Warrens AN, Yazzie NP, Seebach JD, Sachs DH, Sykes M. Cross-species interaction of porcine and human integrins with their respective ligands: implications for xenogeneic tolerance induction. Transplantation. 1998 Aug 15; 66(3):385-94.
    View in: PubMed
  354. Sachs DH. Transplantation tolerance. Transplant Proc. 1998 Aug; 30(5):1627-9.
    View in: PubMed
  355. Warrens AN, Simon AR, Theodore PR, Sachs DH, Sykes M. Function of porcine adhesion molecules in a human marrow microenvironment. Transplantation. 1998 Jul 27; 66(2):252-9.
    View in: PubMed
  356. Kozlowski T, Monroy R, Xu Y, Glaser R, Awwad M, Cooper DK, Sachs DH. Anti-Gal(alpha)1-3Gal antibody response to porcine bone marrow in unmodified baboons and baboons conditioned for tolerance induction. Transplantation. 1998 Jul 27; 66(2):176-82.
    View in: PubMed
  357. Brodersen R, Bijlsma F, Gori K, Jensen KT, Chen W, Dominguez J, Haverson K, Moore PF, Saalmüller A, Sachs D, Slierendrecht WJ, Stokes C, Vainio O, Zuckermann F, Aasted B. Analysis of the immunological cross reactivities of 213 well characterized monoclonal antibodies with specificities against various leucocyte surface antigens of human and 11 animal species. Vet Immunol Immunopathol. 1998 Jun 30; 64(1):1-13.
    View in: PubMed
  358. Kozlowski T, Ierino FL, Lambrigts D, Foley A, Andrews D, Awwad M, Monroy R, Cosimi AB, Cooper DK, Sachs DH. Depletion of anti-Gal(alpha)1-3Gal antibody in baboons by specific alpha-Gal immunoaffinity columns. Xenotransplantation. 1998 May; 5(2):122-31.
    View in: PubMed
  359. Sachs DH, Colvin RB, Cosimi AB, Russell PS, Sykes M, McGregor CG, Platt JL. Xenotransplantation--caution, but no moratorium. Nat Med. 1998 Apr; 4(4):372-3.
    View in: PubMed
  360. Sachs DH. Brushing up on immunological tolerance. Immunologic Tolerance for Immune System Mediated Diseases, Bethesda, MD, USA, 8 December 1997. Mol Med Today. 1998 Mar; 4(3):105-6.
    View in: PubMed
  361. Madsen JC, Yamada K, Allan JS, Choo JK, Erhorn AE, Pins MR, Vesga L, Slisz JK, Sachs DH. Transplantation tolerance prevents cardiac allograft vasculopathy in major histocompatibility complex class I-disparate miniature swine. Transplantation. 1998 Feb 15; 65(3):304-13.
    View in: PubMed
  362. Aasted B, Gori K, Dominguez J, Ezquerra A, Bullido R, Arn S, Bianchi A, Binns R, Chu RM, Davis WC, Denham S, Haverson K, Jensen KT, Kim YB, Magyar A, Petersen KR, Saalmüller A, Sachs D, Schütt C, Shimizu M, Stokes C, Whittall T, Yang H, Zuckermann F. Immunoprecipitation studies of monoclonal antibodies submitted to the Second International Swine CD Workshop. Vet Immunol Immunopathol. 1998 Jan 30; 60(3-4):229-36.
    View in: PubMed
  363. Pescovitz MD, Book BK, Aasted B, Dominguez J, Ezquerra A, Trebichavsky I, Novikov B, Valpotic I, Nielsen J, Arn S, Sachs DH, Lunney JK, Boyd PC, Walker J, Lee R, Lackovic G, Kirkham P, Parkhouse RM, Saalmüller A. Analyses of monoclonal antibodies reacting with porcine CD3: results from the Second International Swine CD Workshop. Vet Immunol Immunopathol. 1998 Jan 30; 60(3-4):261-8.
    View in: PubMed
  364. Pescovitz MD, Book BK, Aasted B, Dominguez J, Bullido R, Trebichavsky I, Novikov B, Valpotic I, Tomaskovic M, Nielsen J, Arn S, Sachs DH, Lunney JK, Boyd PC, Walker J, Lee R, Saalmüller A. Analyses of monoclonal antibodies reacting with porcine CD5: results from the Second International Swine CD Workshop. Vet Immunol Immunopathol. 1998 Jan 30; 60(3-4):269-73.
    View in: PubMed
  365. Pescovitz MD, Book BK, Aasted B, Dominguez J, Bullido R, Trebichavsky I, Novikov B, Valpotic I, Nielsen J, Arn S, Sachs DH, Lunney JK, Boyd PC, Walker J, Lee R, Petrinec N, Saalmüller A. Analyses of monoclonal antibodies reacting with porcine wCD6: results from the Second International Swine CD Workshop. Vet Immunol Immunopathol. 1998 Jan 30; 60(3-4):285-9.
    View in: PubMed
  366. Zuckermann FA, Pescovitz MD, Aasted B, Dominguez J, Trebichavsky I, Novikov B, Valpotic I, Nielsen J, Arn S, Sachs DH, Lunney JK, Boyd P, Walker J, Lee R, Davis WC, Barbosa IR, Saalmüller A. Report on the analyses of mAb reactive with porcine CD8 for the second international swine CD workshop. Vet Immunol Immunopathol. 1998 Jan 30; 60(3-4):291-303.
    View in: PubMed
  367. Saalmüller A, Pauly T, Aasted B, Jensen KT, Sachs DH, Arn S, Davis WC, Park YH, McCullough K, Summerfield A, Murtaugh M, Pampusch MS, Burger KD, Laber J, Nielsen J, Pescovitz MD, Stokes C, Haverson K, Boyd P, Lunney JK. Summary of the first round analyses of the Second International Swine CD Workshop. Vet Immunol Immunopathol. 1998 Jan 30; 60(3-4):237-49.
    View in: PubMed
  368. Saalmüller A, Pauly T, Lunney JK, Boyd P, Aasted B, Sachs DH, Arn S, Bianchi A, Binns RM, Licence S, Whyte A, Blecha F, Chen Z, Chu RM, Davis WC, Denham S, Yang H, Whittall T, Parkhouse RM, Dominguez J, Ezquerra A, Alonso F, Horstick G, Howard C, Zuckermann F, et al. Overview of the Second International Workshop to define swine cluster of differentiation (CD) antigens. Vet Immunol Immunopathol. 1998 Jan 30; 60(3-4):207-28.
    View in: PubMed
  369. Pescovitz MD, Book BK, Aasted B, Dominguez J, Ezquerra A, Trebichavsky I, Novikov B, Valpotic I, Sver L, Nielsen J, Arn S, Sachs DH, Lunney JK, Boyd PC, Walker J, Lee R, Davis W, Barbosa IR, Zuckermann F, Saalmüller A. Summary of workshop findings for antibodies reacting with porcine T-cells and activation antigens: results from the Second International Swine CD Workshop. Vet Immunol Immunopathol. 1998 Jan 30; 60(3-4):251-60.
    View in: PubMed
  370. Xu Y, Lorf T, Sablinski T, Gianello P, Bailin M, Monroy R, Kozlowski T, Awwad M, Cooper DK, Sachs DH. Removal of anti-porcine natural antibodies from human and nonhuman primate plasma in vitro and in vivo by a Galalpha1-3Galbeta1-4betaGlc-X immunoaffinity column. Transplantation. 1998 Jan 27; 65(2):172-9.
    View in: PubMed
  371. Auchincloss H, Sachs DH. Xenogeneic transplantation. Annu Rev Immunol. 1998; 16:433-70.
    View in: PubMed
  372. Colby C, Sykes M, Sachs DH, Spitzer TR. Cellular modulation of acute graft-vs.-host disease. Biol Blood Marrow Transplant. 1997 Dec; 3(6):287-93.
    View in: PubMed
  373. Emery DW, Sablinski T, Shimada H, Germana S, Gianello P, Foley A, Shulman S, Arn S, Fishman J, Lorf T, Nickeleit V, Colvin RB, Sachs DH, LeGuern C. Expression of an allogeneic MHC DRB transgene, through retroviral transduction of bone marrow, induces specific reduction of alloreactivity. Transplantation. 1997 Nov 27; 64(10):1414-23.
    View in: PubMed
  374. Choo JK, Seebach JD, Nickeleit V, Shimizu A, Lei H, Sachs DH, Madsen JC. Species differences in the expression of major histocompatibility complex class II antigens on coronary artery endothelium: implications for cell-mediated xenoreactivity. Transplantation. 1997 Nov 15; 64(9):1315-22.
    View in: PubMed
  375. Seebach JD, Comrack C, Germana S, LeGuern C, Sachs DH, DerSimonian H. HLA-Cw3 expression on porcine endothelial cells protects against xenogeneic cytotoxicity mediated by a subset of human NK cells. J Immunol. 1997 Oct 1; 159(7):3655-61.
    View in: PubMed
  376. Allan JS, Choo JK, Vesga L, Arn JS, Pins MR, Sachs DH, Madsen JC. Cardiac allograft vasculopathy is abrogated by anti-CD8 monoclonal antibody therapy. Ann Thorac Surg. 1997 Oct; 64(4):1019-25.
    View in: PubMed
  377. Kimikawa M, Sachs DH, Colvin RB, Bartholomew A, Kawai T, Cosimi AB. Modifications of the conditioning regimen for achieving mixed chimerism and donor-specific tolerance in cynomolgus monkeys. Transplantation. 1997 Sep 15; 64(5):709-16.
    View in: PubMed
  378. Zhao Y, Sergio JJ, Swenson K, Arn JS, Sachs DH, Sykes M. Positive and negative selection of functional mouse CD4 cells by porcine MHC in pig thymus grafts. J Immunol. 1997 Sep 1; 159(5):2100-7.
    View in: PubMed
  379. Sullivan JA, Oettinger HF, Sachs DH, Edge AS. Analysis of polymorphism in porcine MHC class I genes: alterations in signals recognized by human cytotoxic lymphocytes. J Immunol. 1997 Sep 1; 159(5):2318-26.
    View in: PubMed
  380. Sachs DH. Xenografts, cloning and the immune system. Nat Med. 1997 Sep; 3(9):951-2.
    View in: PubMed
  381. Yamada K, Gianello PR, Ierino FL, Lorf T, Shimizu A, Meehan S, Colvin RB, Sachs DH. Role of the thymus in transplantation tolerance in miniature swine. I. Requirement of the thymus for rapid and stable induction of tolerance to class I-mismatched renal allografts. J Exp Med. 1997 Aug 18; 186(4):497-506.
    View in: PubMed
  382. McMorrow IM, Comrack CA, Nazarey PP, Sachs DH, DerSimonian H. Relationship between ABO blood group and levels of Gal alpha,3Galactose-reactive human immunoglobulin G. Transplantation. 1997 Aug 15; 64(3):546-9.
    View in: PubMed
  383. McMorrow IM, Comrack CA, Sachs DH, DerSimonian H. Heterogeneity of human anti-pig natural antibodies cross-reactive with the Gal(alpha1,3)Galactose epitope. Transplantation. 1997 Aug 15; 64(3):501-10.
    View in: PubMed
  384. Sawada T, Wu Y, Sachs DH, Iacomini J. CD4+ T cells are able to reject class I disparate allografts. Transplantation. 1997 Jul 27; 64(2):335-40.
    View in: PubMed
  385. Sawada T, DellaPelle PA, Seebach JD, Sachs DH, Colvin RB, Iacomini J. Human cell-mediated rejection of porcine xenografts in an immunodeficient mouse model. Transplantation. 1997 May 15; 63(9):1331-8.
    View in: PubMed
  386. Mayfield RS, Hayashi H, Sawada T, Bergen K, LeGuern C, Sykes M, Sachs DH, Iacomini J. The mechanism of specific prolongation of class I-mismatched skin grafts induced by retroviral gene therapy. Eur J Immunol. 1997 May; 27(5):1177-81.
    View in: PubMed
  387. Sablinski T, Gianello PR, Bailin M, Bergen KS, Emery DW, Fishman JA, Foley A, Hatch T, Hawley RJ, Kozlowski T, Lorf T, Meehan S, Monroy R, Powelson JA, Colvin RB, Cosimi AB, Sachs DH. Pig to monkey bone marrow and kidney xenotransplantation. Surgery. 1997 Apr; 121(4):381-91.
    View in: PubMed
  388. Giangrande I, Yamada K, Arn S, Lorf T, Sachs DH, LeGuern C. Selective increase in CD4-positive graft-infiltrating mononuclear cells among the infiltrates in class I disparate kidney grafts undergoing rejection. Transplantation. 1997 Mar 15; 63(5):722-8.
    View in: PubMed
  389. Greenstein JL, Sachs DH. The use of tolerance for transplantation across xenogeneic barriers. Nat Biotechnol. 1997 Mar; 15(3):235-8.
    View in: PubMed
  390. Zhao Y, Fishman JA, Sergio JJ, Oliveros JL, Pearson DA, Szot GL, Wilkinson RA, Arn JS, Sachs DH, Sykes M. Immune restoration by fetal pig thymus grafts in T cell-depleted, thymectomized mice. J Immunol. 1997 Feb 15; 158(4):1641-9.
    View in: PubMed
  391. Yamada K, Gianello PR, Ierino FL, Shimizu A, Meehan S, Colvin RB, Sachs DH. Influence of the thymus on transplantation tolerance in miniature swine. Transplant Proc. 1997 Feb-Mar; 29(1-2):1076.
    View in: PubMed
  392. Germana S, Shimada H, Sachs DH, LeGuern C. Retroviral vectors transfer functional MHC class II heterodimers into bone marrow: a genetic approach to tolerance induction. Transplant Proc. 1997 Feb-Mar; 29(1-2):1129.
    View in: PubMed
  393. Hayashi H, Mayfield RS, Sawada T, Germana S, Sykes M, Iacomini J, Sachs DH, LeGuern C. Role of the thymus in donor specific hyporesponsiveness induced by retroviral transduction of bone marrow using an MHC class I gene. Transplant Proc. 1997 Feb-Mar; 29(1-2):1133.
    View in: PubMed
  394. Giangrande I, Yamada K, Germana S, Sachs D, LeGuern C. Tolerant cells infiltrating class I mismatched swine kidney allografts lack the CD4 single positive subset and down regulate TCR gene expression. Transplant Proc. 1997 Feb-Mar; 29(1-2):1164.
    View in: PubMed
  395. Ierino FL, Yamada K, Hatch T, Sachs DH. Preliminary in vitro evidence for regulatory cells in a miniature swine renal allograft model. Transplant Proc. 1997 Feb-Mar; 29(1-2):1165.
    View in: PubMed
  396. Kawai T, Sachs DH, Hoshino T, Koga S, Tanabe K, Toma H, Ota K, Colvin RB, Cosimi AB. Graft-vs-host tolerance in mixed allogeneic chimerism. Transplant Proc. 1997 Feb-Mar; 29(1-2):1222-3.
    View in: PubMed
  397. Zhao Y, Sergio JJ, Pearson DA, Szot GL, Arn JS, Sachs DH, Sykes M. Repopulation of mouse CD4 cells in BALB/c nude mice receiving fetal pig thymus/liver grafts. Transplant Proc. 1997 Feb-Mar; 29(1-2):1228-9.
    View in: PubMed
  398. Kozlowski T, Fuchimoto Y, Monroy R, Bailin M, Martinez-Ruiz R, Foley A, Xu Y, Awwad M, Fishman J, Andrews D, Ritzenthaler J, Sablinski T, Ierino FL, Sachs DH. Apheresis and column absorption for specific removal of Gal-alpha-1,3 Gal natural antibodies in a pig-to-baboon model. Transplant Proc. 1997 Feb-Mar; 29(1-2):961.
    View in: PubMed
  399. Bartholomew AM, Cosimi AB, Sachs DH, Bailin M, Boskovic S, Colvin R, Hong H, Johnson M, Kimikawa M, Leguern A, Meehan S, Sablinski T, Wee SL, Powelson J. A study of tolerance in a concordant xenograft model. Transplant Proc. 1997 Feb-Mar; 29(1-2):923-4.
    View in: PubMed
  400. Kimikawa M, Kawai T, Sachs DH, Colvin RB, Bartholomew A, Cosimi AB. Mixed chimerism and transplantation tolerance induced by a nonlethal preparative regimen in cynomolgus monkeys. Transplant Proc. 1997 Feb-Mar; 29(1-2):1218.
    View in: PubMed
  401. Shimizu A, Yamada K, Meehan SM, Sachs DH, Colvin RB. Intragraft cellular events associated with tolerance in pig allografts: the "acceptance reaction". Transplant Proc. 1997 Feb-Mar; 29(1-2):1155.
    View in: PubMed
  402. Yasumoto A, Yamada K, Sablinski T, LeGuern C, Sykes M, Sachs DH. Mechanism of tolerance following class II gene transduction of autologous swine bone marrow. Transplant Proc. 1997 Feb-Mar; 29(1-2):1132.
    View in: PubMed
  403. Blancho G, Gianello PR, Lorf T, Germana S, Giangrande I, Mourad G, Colvin RB, Sachs DH, LeGuern C. Molecular and cellular events implicated in local tolerance to kidney allografts in miniature swine. Transplantation. 1997 Jan 15; 63(1):26-33.
    View in: PubMed
  404. Khan A, Sergio JJ, Zhao Y, Pearson DA, Sachs DH, Sykes M. Discordant xenogeneic neonatal thymic transplantation can induce donor-specific tolerance. Transplantation. 1997 Jan 15; 63(1):124-31.
    View in: PubMed
  405. Wood K, Sachs DH. Chimerism and transplantation tolerance: cause and effect. Immunol Today. 1996 Dec; 17(12):584-7; discussion 588.
    View in: PubMed
  406. Zhao Y, Swenson K, Sergio JJ, Arn JS, Sachs DH, Sykes M. Skin graft tolerance across a discordant xenogeneic barrier. Nat Med. 1996 Nov; 2(11):1211-6.
    View in: PubMed
  407. Sachs DH. Transplantation. Curr Opin Immunol. 1996 Oct; 8(5):671-3.
    View in: PubMed
  408. Gianello PR, Sachs DH. Effect of major histocompatibility complex matching on the development of tolerance to primarily vascularized renal allografts: a study in miniature swine. Hum Immunol. 1996 Sep 15; 50(1):1-10.
    View in: PubMed
  409. Hayashi H, LeGuern C, Sachs DH, Sykes M. Alloresistance to K locus class I-mismatched bone marrow engraftment is mediated entirely by CD4+ and CD8+ T cells. Bone Marrow Transplant. 1996 Aug; 18(2):285-92.
    View in: PubMed
  410. Busch MP, Operskalski EA, Mosley JW, Lee TH, Henrard D, Herman S, Sachs DH, Harris M, Huang W, Stram DO. Factors influencing human immunodeficiency virus type 1 transmission by blood transfusion. Transfusion Safety Study Group. J Infect Dis. 1996 Jul; 174(1):26-33.
    View in: PubMed
  411. Emery DW, Sachs DH, LeGuern C. Culture and characterization of hematopoietic progenitor cells from miniature swine. Exp Hematol. 1996 Jul; 24(8):927-35.
    View in: PubMed
  412. Shimada H, Emery DW, Shafer G, Germana S, Sachs DH, LeGuern C. Miniature swine MHC class II heterodimers expressed through double-copy retroviral vectors. Transplant Proc. 1996 Jun; 28(3):1986-9.
    View in: PubMed
  413. Madsen JC, Sachs DH, Fallon JT, Weissman NJ. Cardiac allograft vasculopathy in partially inbred miniature swine. I. Time course, pathology, and dependence on immune mechanisms. J Thorac Cardiovasc Surg. 1996 Jun; 111(6):1230-9.
    View in: PubMed
  414. Nakajima K, Ochiai T, Suzuki T, Gunji Y, Ohta M, Isono K, Sachs DH. T-cell restriction patterns in pig bone marrow chimera. Transplant Proc. 1996 Jun; 28(3):1244-5.
    View in: PubMed
  415. Banerjee PT, Ierino F, Kaynor GC, Giovino M, Sablinski T, Emery DW, Rosa MD, LeGuern C, Sachs DH, Monroy RL. Retrovirus-mediated transfer and expression of swine MHC class II genes in CD34+ monkey stem cells. Transplant Proc. 1996 Apr; 28(2):747-8.
    View in: PubMed
  416. Yamada K, DerSimonian H, Sachs DH. The mechanism of xenogeneic cell-mediated lympholysis between human and pig cells. Transplant Proc. 1996 Apr; 28(2):757.
    View in: PubMed
  417. Paguio CG, Germana S, LeGuern C, Jubinsky P, Sachs DH, Emery DW. Derivation of immortalized swine stromal cell lines. Transplant Proc. 1996 Apr; 28(2):791.
    View in: PubMed
  418. McMorrow IM, Comrack C, Sachs DH, Monroy R, DerSimonian H. Characterization of the human alpha 1,3Gal-reactive natural antibody population. Transplant Proc. 1996 Apr; 28(2):547.
    View in: PubMed
  419. Powelson J, Bailin M, Bartholomew A, Boskebick S, Colvin R, Hong HZ, Johnson M, Kimikawa M, Sablinski T, Wee SL, Sachs D, Cosimi AB. A mixed chimerism approach to renal transplantation between concordant nonhuman primate species. Transplant Proc. 1996 Apr; 28(2):761.
    View in: PubMed
  420. Hayashi H, LeGuern C, Sachs DH, Sykes M. Long-term engraftment of precultured post-5-fluorouracil allogeneic marrow in mice conditioned with a nonmyeloablative regimen: relevance for a gene therapy approach to tolerance induction. Transpl Immunol. 1996 Mar; 4(1):86-90.
    View in: PubMed
  421. Tomita Y, Sachs DH, Khan A, Sykes M. Additional monoclonal antibody (mAB) injections can replace thymic irradiation to allow induction of mixed chimerism and tolerance in mice receiving bone marrow transplantation after conditioning with anti-T cell mABs and 3-Gy whole body irradiation. Transplantation. 1996 Feb 15; 61(3):469-77.
    View in: PubMed
  422. Gianello PR, Yamada K, Fishbein JM, Lorf T, Nickeleit V, Colvin RB, Arn JS, Sachs DH. Long-term acceptance of primarily vascularized renal allografts in miniature swine. Systemic tolerance versus graft adaptation. Transplantation. 1996 Feb 15; 61(3):503-6.
    View in: PubMed
  423. Yamada K, Sachs DH, DerSimonian H. Human anti-porcine xenogeneic T cell response. Evidence for allelic specificity of mixed leukocyte reaction and for both direct and indirect pathways of recognition. J Immunol. 1995 Dec 1; 155(11):5249-56.
    View in: PubMed
  424. Sachs DH, Sykes M, Greenstein JL, Cosimi AB. Tolerance and xenograft survival. Nat Med. 1995 Sep; 1(9):969.
    View in: PubMed
  425. LeGuern C, Shimada H, Emery DW, Germana S, Shafer GE, Sachs DH. Retrovirus-mediated transfer of MHC class II cDNA into swine bone marrow cells. J Mol Med (Berl). 1995 Jun; 73(6):269-78.
    View in: PubMed
  426. Blancho G, Gianello P, Germana S, Baetscher M, Sachs DH, LeGuern C. Molecular identification of porcine interleukin 10: regulation of expression in a kidney allograft model. Proc Natl Acad Sci U S A. 1995 Mar 28; 92(7):2800-4.
    View in: PubMed
  427. Gianello PR, Lorf T, Yamada K, Fishbein JM, Nickeleit V, Vitiello DM, Sachs DH. Induction of tolerance to renal allografts across single-haplotype MHC disparities in miniature swine. Transplantation. 1995 Mar 27; 59(6):884-90.
    View in: PubMed
  428. Gianello PR, Fishbein JM, Rosengard BR, Lorf T, Vitiello DM, Arn JS, Sachs DH. Tolerance to class I-disparate renal allografts in miniature swine. Maintenance of tolerance despite induction of specific antidonor CTL responses. Transplantation. 1995 Mar 15; 59(5):772-7.
    View in: PubMed
  429. Fraser CC, Sykes M, Lee RS, Sachs DH, LeGuern C. Specific unresponsiveness to a retrovirally-transferred class I antigen is controlled through the helper pathway. J Immunol. 1995 Feb 15; 154(4):1587-95.
    View in: PubMed
  430. Yamada K, Sachs DH, DerSimonian H. Direct and indirect recognition of pig class II antigens by human T cells. Transplant Proc. 1995 Feb; 27(1):258-9.
    View in: PubMed
  431. Hayashi H, Lee RS, Germana S, Fraser C, Sykes M, Sachs DH, LeGuern C. Retroviral vectors for long-term expression of allogeneic major histocompatibility complex transduced into syngeneic bone marrow cells. Transplant Proc. 1995 Feb; 27(1):178-9.
    View in: PubMed
  432. Shimada H, Germana S, Banerjee P, Hayashi H, Sachs DH, LeGuern C. A single retroviral vector for transfer of multiple major histocompatibility complex genes: a genetic tool for transplantation tolerance. Transplant Proc. 1995 Feb; 27(1):180-1.
    View in: PubMed
  433. Giangrande I, Gianello P, Lorf T, Vitiello D, LeGuern C, Sachs DH. Humoral response of miniature swine tolerant to class I mismatched renal allografts. Transplant Proc. 1995 Feb; 27(1):559-60.
    View in: PubMed
  434. Kawai T, Cosimi AB, Colvin RB, Powelson J, Eason J, Kozlowski T, Sykes M, Monroy R, Tanaka M, Sachs DH. Mixed allogeneic chimerism and renal allograft tolerance in cynomolgus monkeys. Transplantation. 1995 Jan 27; 59(2):256-62.
    View in: PubMed
  435. Sachs DH. The Imunologic Response to Xenografts. ILAR J. 1995; 37(1):16-22.
    View in: PubMed
  436. Grabbe S, Fishbein JM, Sachs DH, Flotte TJ, Granstein RD. Characterization of cutaneous antigen presentation in partially inbred miniature swine. Exp Dermatol. 1994 Dec; 3(6):276-82.
    View in: PubMed
  437. Gianello PR, Blancho G, Fishbein JF, Lorf T, Nickeleit V, Vitiello D, Sachs DH. Mechanism of cyclosporin-induced tolerance to primarily vascularized allografts in miniature swine. Effect of administration of exogenous IL-2. J Immunol. 1994 Nov 15; 153(10):4788-97.
    View in: PubMed
  438. Lee LA, Gritsch HA, Sergio JJ, Arn JS, Glaser RM, Sablinski T, Sachs DH, Sykes M. Specific tolerance across a discordant xenogeneic transplantation barrier. Proc Natl Acad Sci U S A. 1994 Nov 8; 91(23):10864-7.
    View in: PubMed
  439. Sachs DH. The pig as a potential xenograft donor. Vet Immunol Immunopathol. 1994 Oct; 43(1-3):185-91.
    View in: PubMed
  440. Sykes M, Lee LA, Sachs DH. Xenograft tolerance. Immunol Rev. 1994 Oct; 141:245-76.
    View in: PubMed
  441. Robbins RC, Mitchell ME, Sachs DH, Clark RE. Human plasma causes rapid dysfunction in ex vivo pig hearts. J Heart Lung Transplant. 1994 Sep-Oct; 13(5):877-81.
    View in: PubMed
  442. Smith CV, Sablinski T, Arn JS, Myers DE, Rosengard BR, Uckun FM, Sachs DH. In vivo treatment with monoclonal antibodies directed against CD4 and CD8 antigens in miniature swine. J Immunother Emphasis Tumor Immunol. 1994 Aug; 16(2):105-14.
    View in: PubMed
  443. Lee LA, Gritsch HA, Arn JS, Emery DW, Glaser RM, Sablinski T, Sachs DH, Sykes M. Induction of tolerance to pig antigens in mice grafted with fetal pig thymus/liver grafts. Transplant Proc. 1994 Jun; 26(3):1300-1.
    View in: PubMed
  444. Emery DW, Sykes M, Sachs DH, LeGuern C. Mixed swine/human long-term bone marrow cultures. Transplant Proc. 1994 Jun; 26(3):1313-4.
    View in: PubMed
  445. Lee LA, Sergio JJ, Sachs DH, Sykes M. Mechanism of tolerance in mixed xenogeneic chimeras prepared with a nonmyeloablative conditioning regimen. Transplant Proc. 1994 Jun; 26(3):1197-8.
    View in: PubMed
  446. Fishbein JM, Rosengard BR, Gianello P, Nickeleit V, Guzzetta PC, Smith CV, Nakajima K, Vitiello D, Hill GM, Sachs DH. Development of tolerance to class II-mismatched renal transplants after a short course of cyclosporine therapy in miniature swine. Transplantation. 1994 May 15; 57(9):1303-8.
    View in: PubMed
  447. Rosengard BR, Fishbein JM, Gianello P, Ojikutu CA, Guzzetta PC, Smith CV, Sundt TM, Nakajima K, Hill GS, Sachs DH. Retransplantation in miniature swine. Lack of a requirement for graft adaptation for maintenance of specific renal allograft tolerance. Transplantation. 1994 Mar 27; 57(6):794-9.
    View in: PubMed
  448. Gritsch HA, Glaser RM, Emery DW, Lee LA, Smith CV, Sablinski T, Arn JS, Sachs DH, Sykes M. The importance of nonimmune factors in reconstitution by discordant xenogeneic hematopoietic cells. Transplantation. 1994 Mar 27; 57(6):906-17.
    View in: PubMed
  449. Sachs DH. The pig as a xenograft donor. Pathol Biol (Paris). 1994 Mar; 42(3):217-9.
    View in: PubMed
  450. Tomita Y, Sachs DH, Sykes M. Myelosuppressive conditioning is required to achieve engraftment of pluripotent stem cells contained in moderate doses of syngeneic bone marrow. Blood. 1994 Feb 15; 83(4):939-48.
    View in: PubMed
  451. Latinne D, Vitiello DM, Sachs DH, Sykes M. Tolerance to discordant xenografts. I. Sharing of human natural antibody determinants on miniature swine bone marrow cells and endothelial cells. Transplantation. 1994 Jan; 57(2):238-45.
    View in: PubMed
  452. Emery DW, Sablinski T, Arn JS, LeGuern C, Sachs DH. Bone marrow culture and transduction of stem cells in a miniature swine model. Blood Cells. 1994; 20(2-3):498-502; discussion 502-3.
    View in: PubMed
  453. Sachs DH. CCETS Basic Science Lecture. Transplantation tolerance. Ann Thorac Surg. 1993 Dec; 56(6):1221-7.
    View in: PubMed
  454. Smith CV, Suzuki T, Guzzetta PC, Nakajima K, Sundt TM, Mixon A, Spitzer TR, Eckhaus MA, Sachs DH. Bone marrow transplantation in miniature swine: IV. Development of myeloablative regimens that allow engraftment across major histocompatibility barriers. Transplantation. 1993 Sep; 56(3):541-9.
    View in: PubMed
  455. Gustafsson K, Germana S, Sundt TM, Sachs DH, LeGuern C. Extensive allelic polymorphism in the CDR2-like region of the miniature swine CD4 molecule. J Immunol. 1993 Aug 1; 151(3):1365-70.
    View in: PubMed
  456. Gianello P, Fishbein JM, Sachs DH. Tolerance to primarily vascularized allografts in miniature swine. Immunol Rev. 1993 Jun; 133:19-44.
    View in: PubMed
  457. Emery DW, Shafer GE, Karson EM, Sachs DH, LeGuern C. Retrovirus-mediated transfer and expression of an allogeneic major histocompatibility complex class II DRB cDNA in swine bone marrow cultures. Blood. 1993 May 1; 81(9):2460-5.
    View in: PubMed
  458. Sachs DH, Smith CV, Emery DW, LeGuern C, Bodine D, Nienhuis A, Sykes M. Induction of specific tolerance to MHC-disparate allografts through genetic engineering. Exp Nephrol. 1993 Mar-Apr; 1(2):128-33.
    View in: PubMed
  459. Fishbein JM, Gianello P, Nickeleit V, Vitiello D, Blancho G, Latinne D, Nakajima K, Rosengard B, Colvin R, Sachs DH. Interleukin-2 reverses the ability of cyclosporine to induce tolerance to class I disparate kidney allografts in miniature swine. Transplant Proc. 1993 Feb; 25(1 Pt 1):322-3.
    View in: PubMed
  460. Hirsch F, Poncet P, Freeman S, Gress RE, Sachs DH, Druet P, Hirsch R. Antifection: a new method for targeted gene transfection. Transplant Proc. 1993 Feb; 25(1 Pt 1):138-9.
    View in: PubMed
  461. Smith CV, Fishbein J, Nakajima K, Rosengard BR, Guzzetta PC, Sachs DH. Effect of tolerance to allogeneic major histocompatibility complex antigens on rejection across minor antigen differences. Transplant Proc. 1993 Feb; 25(1 Pt 1):364-5.
    View in: PubMed
  462. Sachs DH, Bodine DM, Moulton AD, Pearson DA, Nienhuis AW, Sykes M. Tolerance induction using autologous bone marrow modified with an allogeneic class I MHC gene. Transplant Proc. 1993 Feb; 25(1 Pt 1):348-9.
    View in: PubMed
  463. Lee LA, Sachs DH, Sykes M. Effect of natural killer cell depletion on long-term multilineage allogeneic bone marrow engraftment. Transplant Proc. 1993 Feb; 25(1 Pt 2):1246-7.
    View in: PubMed
  464. Emery DW, Smith CV, Shafer GE, Karson EM, Sachs DH, LeGuern C. Expression of allogeneic class II cDNA in swine peripheral blood mononuclear cells following retroviral-mediated gene transfer into bone marrow. Transplant Proc. 1993 Feb; 25(1 Pt 1):140-1.
    View in: PubMed
  465. Sykes M, Sachs DH, Nienhuis AW, Pearson DA, Moulton AD, Bodine DM. Specific prolongation of skin graft survival following retroviral transduction of bone marrow with an allogeneic major histocompatibility complex gene. Transplantation. 1993 Jan; 55(1):197-202.
    View in: PubMed
  466. Sundt TM, Arn JS, Sachs DH. Patterns of T cell-accessory cell interaction in the generation of primary alloresponses in the pig. Transplantation. 1992 Nov; 54(5):911-6.
    View in: PubMed
  467. Rosengard BR, Ojikutu CA, Guzzetta PC, Smith CV, Sundt TM, Nakajima K, Boorstein SM, Hill GS, Fishbein JM, Sachs DH. Induction of specific tolerance to class I-disparate renal allografts in miniature swine with cyclosporine. Transplantation. 1992 Sep; 54(3):490-7.
    View in: PubMed
  468. Rosengard BR, Ojikutu CA, Fishbein J, Kortz EO, Sachs DH. Selective breeding of miniature swine leads to an increased rate of acceptance of MHC-identical, but not of class I-disparate, renal allografts. J Immunol. 1992 Aug 1; 149(3):1099-103.
    View in: PubMed
  469. Hirsch F, Germana S, Gustafsson K, Pratt K, Sachs DH, Leguern C. Structure and expression of class II alpha genes in miniature swine. J Immunol. 1992 Aug 1; 149(3):841-6.
    View in: PubMed
  470. Abraham VS, Sachs DH, Sykes M. Mechanism of protection from graft-versus-host disease mortality by IL-2. III. Early reductions in donor T cell subsets and expansion of a CD3+CD4-CD8- cell population. J Immunol. 1992 Jun 15; 148(12):3746-52.
    View in: PubMed
  471. Sundt TM, LeGuern C, Germana S, Smith CV, Nakajima K, Lunney JK, Sachs DH. Characterization of a polymorphism of CD4 in miniature swine. J Immunol. 1992 May 15; 148(10):3195-201.
    View in: PubMed
  472. Aksentijevich I, Sachs DH, Sykes M. Humoral tolerance in xenogeneic BMT recipients conditioned by a nonmyeloablative regimen. Transplantation. 1992 May; 53(5):1108-14.
    View in: PubMed
  473. Nakajima K, Smith CV, Mixon A, Sykes M, Guzzetta PC, Spitzer TR, Eckhaus MA, Sachs DH. In vitro and in vivo effects of recombinant human interleukin-2 in naive miniature swine. J Immunother (1991). 1992 Apr; 11(3):169-75.
    View in: PubMed
  474. Emery DW, Shafer GE, Karson EM, Sachs DH, LeGuern C. Expression of allogeneic class II cDNA in swine bone marrow cells transduced with a recombinant retrovirus. Transplant Proc. 1992 Apr; 24(2):468-9.
    View in: PubMed
  475. Sykes M, Sachs DH, Aksentijevich I. Effect of natural antibody on xenogeneic bone marrow engraftment. Transplant Proc. 1992 Apr; 24(2):497-8.
    View in: PubMed
  476. Sharabi Y, Abraham VS, Sykes M, Sachs DH. Mixed allogeneic chimeras prepared by a non-myeloablative regimen: requirement for chimerism to maintain tolerance. Bone Marrow Transplant. 1992 Mar; 9(3):191-7.
    View in: PubMed
  477. Mickisch GH, Aksentijevich I, Schoenlein PV, Goldstein LJ, Galski H, Stahle C, Sachs DH, Pastan I, Gottesman MM. Transplantation of bone marrow cells from transgenic mice expressing the human MDR1 gene results in long-term protection against the myelosuppressive effect of chemotherapy in mice. Blood. 1992 Feb 15; 79(4):1087-93.
    View in: PubMed
  478. Smith CV, Nakajima K, Mixon A, Guzzetta PC, Rosengard BR, Fishbein JM, Sachs DH. Successful induction of long-term specific tolerance to fully allogeneic renal allografts in miniature swine. Transplantation. 1992 Feb; 53(2):438-44.
    View in: PubMed
  479. Blaison G, Weber JC, Sachs D, Korganow AS, Martin T, Kretz JG, Pasquali JL. [Rhabdomyolysis caused by simvastatinin a patient following heart transplantation and cyclosporine therapy]. Rev Med Interne. 1992 Jan-Feb; 13(1):61-3.
    View in: PubMed
  480. Aksentijevich I, Sachs DH, Sykes M. Natural antibodies can inhibit bone marrow engraftment in the rat----mouse species combination. J Immunol. 1991 Dec 15; 147(12):4140-6.
    View in: PubMed
  481. Rosengard BR, Kortz EO, Ojikutu CA, Guzzetta PC, Sundt TM, Smith CV, Nakajima K, Boorstein SM, Hill GS, Sachs DH. The failure of skin grafting to break tolerance to class I-disparate renal allografts in miniature swine despite inducing marked antidonor cellular immunity. Transplantation. 1991 Dec; 52(6):1044-52.
    View in: PubMed
  482. Shafer GE, Emery DW, Gustafsson K, Germana S, Anderson WF, Sachs DH, LeGuern C. Expression of a swine class II gene in murine bone marrow hematopoietic cells by retroviral-mediated gene transfer. Proc Natl Acad Sci U S A. 1991 Nov 1; 88(21):9760-4.
    View in: PubMed
  483. Sachs DH. Specific transplantation tolerance. N Engl J Med. 1991 Oct 24; 325(17):1240-2.
    View in: PubMed
  484. Smith CV, Rosengard BR, Guzzetta PC, Nakajima K, Sachs DH. New approaches to transplantation tolerance. Transplant Proc. 1991 Aug; 23(4):2157-61.
    View in: PubMed
  485. Aksentijevich I, Sachs DH, Sykes M. Natural antibodies against bone marrow cells of a concordant xenogeneic species. J Immunol. 1991 Jul 1; 147(1):79-85.
    View in: PubMed
  486. Guzzetta PC, Sundt TM, Suzuki T, Mixon A, Rosengard BR, Sachs DH. Induction of kidney transplantation tolerance across major histocompatibility complex barriers by bone marrow transplantation in miniature swine. Transplantation. 1991 Apr; 51(4):862-6.
    View in: PubMed
  487. Aksentijevich I, Sharabi Y, Sundt TM, Sachs DH, Sykes M. Humoral tolerance in mixed xenogeneic chimeras prepared by a nonmyeloablative conditioning regimen. Transplant Proc. 1991 Feb; 23(1 Pt 1):880-2.
    View in: PubMed
  488. LeGuern C, Shafer GE, Alexander RC, Germana S, Gustafsson K, el-Gamil M, Sachs DH. Expression of swine class II genes using recombinant retroviral vectors. Transplant Proc. 1991 Feb; 23(1 Pt 1):427-8.
    View in: PubMed
  489. Rosengard BR, Ojikutu CA, Guzzetta PC, Smith CV, Sundt TM, Nakajima K, Boorstein SM, Hill GS, Sachs DH. Renal transplantation in miniature swine: preliminary evidence that graft infiltrating leukocytes suppress donor-specific cell-mediated lymphocytotoxicity in co-culture. Transplant Proc. 1991 Feb; 23(1 Pt 1):189-91.
    View in: PubMed
  490. Nakajima K, Smith CV, Mixon A, Rosengard BR, Guzzetta PC, Spitzer TR, Eckhaus MA, Sachs DH. The effects of recombinant human IL-2 in miniature swine. Transplant Proc. 1991 Feb; 23(1 Pt 1):248-50.
    View in: PubMed
  491. Sachs DH. Basic science highlights at the 1990 Congress. Transplant Proc. 1991 Feb; 23(1 Pt 1):28-31.
    View in: PubMed
  492. Sundt TM, LeGuern C, Smith CV, Sachs DH. Identification of a CD4 polymorphism in swine. Transplant Proc. 1991 Feb; 23(1 Pt 1):419-20.
    View in: PubMed
  493. Boorstein SM, Rosengard BR, Sachs DH. In vitro studies involving APC-depleted responder cells suggest the existence of a CD8+ direct recognition pathway in miniature swine. Transplant Proc. 1991 Feb; 23(1 Pt 1):828-9.
    View in: PubMed
  494. Gustafsson K, Germana S, Hirsch F, Pratt K, LeGuern C, Sachs DH. Structure of miniature swine class II DRB genes: conservation of hypervariable amino acid residues between distantly related mammalian species. Proc Natl Acad Sci U S A. 1990 Dec; 87(24):9798-802.
    View in: PubMed
  495. Sykes M, Sachs DH. Bone marrow transplantation as a means of inducing tolerance. Semin Immunol. 1990 Nov; 2(6):401-17.
    View in: PubMed
  496. Auchincloss H, Moses R, Conti D, Sundt T, Smith C, Sachs DH, Winn HJ. Xenograft rejection of class I-expressing transgenic skin is CD4-dependent and CD8-independent. Transplant Proc. 1990 Oct; 22(5):2335-6.
    View in: PubMed
  497. Gustafsson K, LeGuern C, Hirsch F, Germana S, Pratt K, Sachs DH. Class II genes of miniature swine. IV. Characterization and expression of two allelic class II DQB cDNA clones. J Immunol. 1990 Sep 15; 145(6):1946-51.
    View in: PubMed
  498. Sykes M, Hoyles KA, Romick ML, Sachs DH. In vitro and in vivo analysis of bone marrow-derived CD3+, CD4-, CD8-, NK1.1+ cell lines. Cell Immunol. 1990 Sep; 129(2):478-93.
    View in: PubMed
  499. Sykes M, Romick ML, Sachs DH. Interleukin 2 prevents graft-versus-host disease while preserving the graft-versus-leukemia effect of allogeneic T cells. Proc Natl Acad Sci U S A. 1990 Aug; 87(15):5633-7.
    View in: PubMed
  500. Suzuki T, Sundt TM, Mixon A, Sachs DH. In vivo treatment with antiporcine T cell antibodies. Transplantation. 1990 Jul; 50(1):76-81.
    View in: PubMed
  501. Sharabi Y, Aksentijevich I, Sundt TM, Sachs DH, Sykes M. Specific tolerance induction across a xenogeneic barrier: production of mixed rat/mouse lymphohematopoietic chimeras using a nonlethal preparative regimen. J Exp Med. 1990 Jul 1; 172(1):195-202.
    View in: PubMed
  502. Auchincloss H, Moses R, Conti D, Sundt T, Smith C, Sachs DH, Winn HJ. Rejection of transgenic skin expressing a xeno-class I antigen is CD4-dependent and CD8-independent. Transplant Proc. 1990 Jun; 22(3):1059-60.
    View in: PubMed
  503. Kortz EO, Sakamoto K, Suzuki T, Guzzetta PC, Chester CH, Lunney JK, Sachs DH. Mechanism of tolerance following class I--disparate renal allografts in miniature swine. Cellular responses of tolerant animals. Transplantation. 1990 Jun; 49(6):1142-9.
    View in: PubMed
  504. Rosengard BR, Kortz EO, Guzzetta PC, Sundt TM, Ojikutu CA, Alexander RB, Sachs DH. Transplantation in miniature swine: analysis of graft-infiltrating lymphocytes provides evidence for local suppression. Hum Immunol. 1990 Jun; 28(2):153-8.
    View in: PubMed
  505. Sachs DH, Bach FH. Immunology of xenograft rejection. Hum Immunol. 1990 Jun; 28(2):245-51.
    View in: PubMed
  506. Sykes M, Sharabi Y, Sachs DH. Natural suppressor cells in spleens of irradiated, bone marrow-reconstituted mice and normal bone marrow: lack of Sca-1 expression and enrichment by depletion of Mac1-positive cells. Cell Immunol. 1990 May; 127(2):260-74.
    View in: PubMed
  507. Pescovitz MD, Hsu SM, Katz SI, Lunney JK, Shimada S, Sachs DH. Characterization of a porcine CD1-specific mAb that distinguishes CD4/CD8 double-positive thymic from peripheral T lymphocytes. Tissue Antigens. 1990 Apr; 35(4):151-6.
    View in: PubMed
  508. Sykes M, Romick ML, Hoyles KA, Sachs DH. In vivo administration of interleukin 2 plus T cell-depleted syngeneic marrow prevents graft-versus-host disease mortality and permits alloengraftment. J Exp Med. 1990 Mar 1; 171(3):645-58.
    View in: PubMed
  509. Rosengard BR, Sachs DH. The first basic sciences symposium of the Transplantation Society. Immunol Today. 1990 Mar; 11(3):67-8.
    View in: PubMed
  510. Hirsch F, Sachs DH, Gustafsson K, Pratt K, Germana S, LeGuern C. Class II genes of miniature swine. III. Characterization of an expressed pig class II gene homologous to HLA-DQA. Immunogenetics. 1990; 31(1):52-6.
    View in: PubMed
  511. Blau A, Herzog D, Shechter P, Sachs D, Eliahou HE. Calcium channel blocker nisoldipine in chronic renal failure. Ren Fail. 1990; 12(2):113-9.
    View in: PubMed
  512. Sharabi Y, Sachs DH. In vivo effects of monoclonal antibodies to distinct epitopes of Qa-2 antigens. J Exp Med. 1990 Jan 1; 171(1):211-9.
    View in: PubMed
  513. Epstein SL, Arn JS, Sachs DH. Seven new MHC recombinant strains defining new H-2 haplotypes. Immunogenetics. 1990; 32(2):142-5.
    View in: PubMed
  514. Pratt K, Sachs DH, Germana S, el-Gamil M, Hirsch F, Gustafsson K, LeGuern C. Class II genes of miniature swine. II. Molecular identification and characterization of B (beta) genes from the SLAc haplotype. Immunogenetics. 1990; 31(1):1-6.
    View in: PubMed
  515. Sykes M, Chester CH, Sundt TM, Romick ML, Hoyles KA, Sachs DH. Effects of T cell depletion in radiation bone marrow chimeras. III. Characterization of allogeneic bone marrow cell populations that increase allogeneic chimerism independently of graft-vs-host disease in mixed marrow recipients. J Immunol. 1989 Dec 1; 143(11):3503-11.
    View in: PubMed
  516. Sykes M, Bukhari Z, Sachs DH. Graft-versus-leukemia effect using mixed allogeneic bone marrow transplantation. Bone Marrow Transplant. 1989 Sep; 4(5):465-74.
    View in: PubMed
  517. Rüedi E, Sykes M, Ildstad ST, Chester CH, Althage A, Hengartner H, Sachs DH, Zinkernagel RM. Antiviral T cell competence and restriction specificity of mixed allogeneic (P1 + P2----P1) irradiation chimeras. Cell Immunol. 1989 Jun; 121(1):185-95.
    View in: PubMed
  518. Chester CH, Sykes M, Sachs DH. Multiple mixed chimeras: reconstitution of lethally irradiated mice with syngeneic plus allogeneic bone marrow from multiple strains. Res Immunol. 1989 Jun-Aug; 140(5-6):503-16.
    View in: PubMed
  519. Sharrow SO, Arn JS, Stroynowski I, Hood L, Sachs DH. Epitope clusters of Qa-2 antigens defined by a panel of new monoclonal antibodies. J Immunol. 1989 May 15; 142(10):3495-502.
    View in: PubMed
  520. Hirsch R, Chatenoud L, Gress RE, Sachs DH, Bach JF, Bluestone JA. Suppression of the humoral response to anti-CD3 monoclonal antibody. Transplantation. 1989 May; 47(5):853-7.
    View in: PubMed
  521. Moses RD, Orr KS, Bacher JD, Sachs DH, Clark RE, Gress RE. Cardiac allograft survival across major histocompatibility complex barriers in the rhesus monkey following T lymphocyte-depleted autologous marrow transplantation. II. Prolonged allograft survival with extensive marrow T cell depletion. Transplantation. 1989 Mar; 47(3):435-44.
    View in: PubMed
  522. Chester CH, Sykes M, Sachs DH. The recovery of resistance to alloengraftment following lethal irradiation and administration of T cell-depleted syngeneic bone marrow. Bone Marrow Transplant. 1989 Mar; 4(2):195-200.
    View in: PubMed
  523. Kortz EO, Sachs DH. Suppression of CML reactivity by non-T cells from miniature swine tolerant of a class I mismatched renal allograft. Curr Surg. 1989 Mar-Apr; 46(2):107-10.
    View in: PubMed
  524. Epstein SL, Misplon JA, Arn JS, Max EE, Johnson-Leva R, Harvath L, Sachs DH. Inheritance of idiotype expression unlinked to the H chain allotype locus. Novel features of genetic control in the Ia.7 system. J Immunol. 1989 Mar 1; 142(5):1596-604.
    View in: PubMed
  525. Hirsch R, Chatenoud L, Gress RE, Bach JF, Sachs DH, Bluestone JA. Suppression of the humoral response to anti-CD3 mAB by pretreatment with anti-CD4 mAB. Transplant Proc. 1989 Feb; 21(1 Pt 1):1015-6.
    View in: PubMed
  526. Sharabi Y, Sachs DH. Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen. J Exp Med. 1989 Feb 1; 169(2):493-502.
    View in: PubMed
  527. Sachs DH, Stone K, Arn JS. Reassessment of the role of class II antigens in skin graft rejection. Transplant Proc. 1989 Feb; 21(1 Pt 1):595-7.
    View in: PubMed
  528. Sykes M, Sachs DH. Genetic analysis of the anti-leukemic effect of mixed allogeneic bone marrow transplantation. Transplant Proc. 1989 Feb; 21(1 Pt 3):3022-4.
    View in: PubMed
  529. Suzuki T, Sundt TM, Kortz EO, Mixon A, Eckhaus MA, Gress RE, Spitzer TR, Sachs DH. Bone marrow transplantation across an MHC barrier in miniature swine. Transplant Proc. 1989 Feb; 21(1 Pt 3):3076-8.
    View in: PubMed
  530. Sharabi Y, Sachs DH. Engraftment of allogeneic bone marrow following administration of anti-T cell monoclonal antibodies and low-dose irradiation. Transplant Proc. 1989 Feb; 21(1 Pt 1):233-5.
    View in: PubMed
  531. Shinohara N, Watanabe M, Sachs DH, Hozumi N. Killing of antigen-reactive B cells by class II-restricted, soluble antigen-specific CD8+ cytolytic T lymphocytes. Nature. 1988 Dec 1; 336(6198):481-4.
    View in: PubMed
  532. Sykes M, Sheard MA, Sachs DH. Graft-versus-host-related immunosuppression is induced in mixed chimeras by alloresponses against either host or donor lymphohematopoietic cells. J Exp Med. 1988 Dec 1; 168(6):2391-6.
    View in: PubMed
  533. Sundt TM, Sachs DH. Applications of molecular biology to transplantation tolerance. Immunol Today. 1988 Nov; 9(11):342-4.
    View in: PubMed
  534. Epstein SL, Sharrow SO, Sachs DH. Genetics of the induction of antigen-specific immunity in anti-idiotype-treated mice and derivation of monoclonal Ab3 antibodies. Ann Inst Pasteur Immunol. 1988 Nov-Dec; 139(6):689-700.
    View in: PubMed
  535. Pescovitz MD, Lowman MA, Sachs DH. Expression of T-cell associated antigens by porcine natural killer cells. Immunology. 1988 Oct; 65(2):267-71.
    View in: PubMed
  536. Sykes M, Sheard M, Sachs DH. Effects of T cell depletion in radiation bone marrow chimeras. I. Evidence for a donor cell population which increases allogeneic chimerism but which lacks the potential to produce GVHD. J Immunol. 1988 Oct 1; 141(7):2282-8.
    View in: PubMed
  537. Sykes M, Sharabi Y, Sachs DH. Achieving alloengraftment without graft-versus-host disease: approaches using mixed allogeneic bone marrow transplantation. Bone Marrow Transplant. 1988 Sep; 3(5):379-86.
    View in: PubMed
  538. Sykes M, Sachs DH. Mechanisms of suppression in mixed allogeneic chimeras. Transplantation. 1988 Aug; 46(2 Suppl):135S-142S.
    View in: PubMed
  539. Sykes M, Chester CH, Sachs DH. Protection from graft-versus-host disease in fully allogeneic chimeras by prior administration of T cell-depleted syngeneic bone marrow. Transplantation. 1988 Aug; 46(2):327-30.
    View in: PubMed
  540. Sachs DH. Anti-idiotype to MHC receptors--a possible route to specific transplantation tolerance? Int Rev Immunol. 1988 Aug; 3(4):313-21.
    View in: PubMed
  541. Sykes M, Sheard MA, Sachs DH. Effects of T cell depletion in radiation bone marrow chimeras. II. Requirement for allogeneic T cells in the reconstituting bone marrow inoculum for subsequent resistance to breaking of tolerance. J Exp Med. 1988 Aug 1; 168(2):661-73.
    View in: PubMed
  542. Hirsch R, Eckhaus M, Auchincloss H, Sachs DH, Bluestone JA. Effects of in vivo administration of anti-T3 monoclonal antibody on T cell function in mice. I. Immunosuppression of transplantation responses. J Immunol. 1988 Jun 1; 140(11):3766-72.
    View in: PubMed
  543. Sakamoto K, Sachs DH, Shimada S, Popitz-Bergez FA, Pennington LR, Pescovitz MD, McDonough MA, MacVittie TJ, Katz SI, Gress RE. Bone marrow transplantation in miniature swine. III. Graft-versus-host disease and the effect of T cell depletion of marrow. Transplantation. 1988 May; 45(5):869-75.
    View in: PubMed
  544. Sykes M, Eisenthal A, Sachs DH. Mechanism of protection from graft-vs-host disease in murine mixed allogeneic chimeras. I. Development of a null cell population suppressive of cell-mediated lympholysis responses and derived from the syngeneic bone marrow component. J Immunol. 1988 May 1; 140(9):2903-11.
    View in: PubMed
  545. Shinohara N, Hozumi N, Watanabe M, Bluestone JA, Johnson-Leva R, Sachs DH. Class II antigen-specific murine cytolytic T lymphocytes (CTL). II. Genuine class II specificity of Lyt-2+ CTL clones. J Immunol. 1988 Jan 1; 140(1):30-6.
    View in: PubMed
  546. Popitz-Bergez FA, Sakamoto K, Pennington LR, Pescovitz MD, McDonough MA, MacVittie TJ, Gress RE, Sachs DH. Bone marrow transplantation in miniature swine. II. Effect of selective genetic differences on marrow engraftment and recipient survival. Transplantation. 1988 Jan; 45(1):27-31.
    View in: PubMed
  547. Sykes M, Sachs DH. Mixed allogeneic chimerism as an approach to transplantation tolerance. Immunol Today. 1988 Jan; 9(1):23-7.
    View in: PubMed
  548. Pennington LR, Sakamoto K, Popitz-Bergez FA, Pescovitz MD, McDonough MA, MacVittie TJ, Gress RE, Sachs DH. Bone marrow transplantation in miniature swine. I. Development of the model. Transplantation. 1988 Jan; 45(1):21-6.
    View in: PubMed
  549. Sachs DH, Germana S, el-Gamil M, Gustafsson K, Hirsch F, Pratt K. Class II genes of miniature swine. I. Class II gene characterization by RFLP and by isolation from a genomic library. Immunogenetics. 1988; 28(1):22-9.
    View in: PubMed
  550. Gress R, Moses R, Suzuki T, Lowman M, Pennington L, Sakamoto K, Sachs DH. Biparental bone marrow transplantation as a means of tolerance induction. Transplant Proc. 1987 Dec; 19(6 Suppl 7):95-7.
    View in: PubMed
  551. Bach FH, Sachs DH. Current concepts: immunology. Transplantation immunology. N Engl J Med. 1987 Aug 20; 317(8):489-92.
    View in: PubMed
  552. Gustafsson K, Widmark E, Jonsson AK, Servenius B, Sachs DH, Larhammar D, Rask L, Peterson PA. Class II genes of the human major histocompatibility complex. Evolution of the DP region as deduced from nucleotide sequences of the four genes. J Biol Chem. 1987 Jun 25; 262(18):8778-86.
    View in: PubMed
  553. Devaux CA, Covell DG, Barbet J, el Gamil M, Sachs DH. Inhibition of the catalytic properties of Staphylococcus aureus nuclease by monoclonal antibodies. Mol Cell Biochem. 1987 Apr; 74(2):117-28.
    View in: PubMed
  554. Shiloni E, Eisenthal A, Sachs D, Rosenberg SA. Antibody-dependent cellular cytotoxicity mediated by murine lymphocytes activated in recombinant interleukin 2. J Immunol. 1987 Mar 15; 138(6):1992-8.
    View in: PubMed
  555. Leo O, Foo M, Sachs DH, Samelson LE, Bluestone JA. Identification of a monoclonal antibody specific for a murine T3 polypeptide. Proc Natl Acad Sci U S A. 1987 Mar; 84(5):1374-8.
    View in: PubMed
  556. Sachs DH. Specific immunosuppression. Transplant Proc. 1987 Feb; 19(1 Pt 1):123-7.
    View in: PubMed
  557. Kortz EO, Sachs DH. Mechanism of specific transplantation tolerance induction by vascular allografts across a class I difference in miniature swine. Transplant Proc. 1987 Feb; 19(1 Pt 1):861-3.
    View in: PubMed
  558. Chatterjee-Das S, Lillehoj EP, Hernandez DM, Coligan JE, Sachs DH. Analysis of the D-region products of H-2q using monoclonal antibodies reveals the expression of a new class I-like molecule. Immunogenetics. 1987; 25(1):7-14.
    View in: PubMed
  559. Leo O, Sachs DH, Samelson LE, Foo M, Quinones R, Gress R, Bluestone JA. Identification of monoclonal antibodies specific for the T cell receptor complex by Fc receptor-mediated CTL lysis. J Immunol. 1986 Dec 15; 137(12):3874-80.
    View in: PubMed
  560. Finnegan A, Smith MA, Smith JA, Berzofsky J, Sachs DH, Hodes RJ. The T cell repertoire for recognition of a phylogenetically distant protein antigen. Peptide specificity and MHC restriction of staphylococcal nuclease-specific T cell clones. J Exp Med. 1986 Sep 1; 164(3):897-910.
    View in: PubMed
  561. Rabinowitz R, Pescovitz MD, Sachs DH. Anti-idiotype to monoclonal anti-swine SLA antibody detects a common idiotype shared by mouse anti-SLA sera and elicits an anti-SLA activity. Immunology. 1986 Aug; 58(4):607-13.
    View in: PubMed
  562. Devaux CA, Pierres M, Epstein SL, Sachs DH. Xenogeneic antibodies with apparent public idiotypic specificity for anti-Ia.7 antibodies are directed in part against V kappa 21D and E subgroup marker. J Immunol. 1986 May 15; 136(10):3760-6.
    View in: PubMed
  563. Ildstad ST, Bluestone JA, Sachs DH. Alloresistance to engraftment of allogeneic donor bone marrow is mediated by an Lyt-2+ T cell in mixed allogeneic reconstitution (C57BL/10Sn + B10.D2/nSn----C57BL/10Sn). J Exp Med. 1986 May 1; 163(5):1343-8.
    View in: PubMed
  564. Bluestone JA, Leo O, Epstein SL, Sachs DH. Idiotypic manipulation of the immune response to transplantation antigens. Immunol Rev. 1986 Apr; 90:5-27.
    View in: PubMed
  565. Shinohara N, Bluestone JA, Sachs DH. Cloned cytotoxic T lymphocytes that recognize an I-A region product in the context of a class I antigen. J Exp Med. 1986 Apr 1; 163(4):972-80.
    View in: PubMed
  566. Maloy WL, Ozato K, Sachs DH, Coligan JE. Evidence for the association of I-A and I-E molecules in d-haplotype mice. Mol Immunol. 1986 Mar; 23(3):263-9.
    View in: PubMed
  567. Ildstad ST, Wren SM, Stephany D, Sachs DH. Effect of selective T cell depletions in mixed xenogeneic reconstitution on specific hyporeactivity to transplantation across a species barrier. Transplantation. 1986 Mar; 41(3):372-6.
    View in: PubMed
  568. Simpson E, Lieberman R, Andó I, Sachs DH, Paul WE, Berzofsky JA. How many class II immune response genes? A reappraisal of the evidence. Immunogenetics. 1986; 23(5):302-8.
    View in: PubMed
  569. Rabinowitz R, Sharrow SO, Chatterjee-Das S, Rogers MJ, Sachs DH. Qa alloantigen expression on functional T lymphocytes from spleen and thymus. Immunogenetics. 1986; 24(6):391-401.
    View in: PubMed
  570. Epstein SL, Arn JS, Sachs DH. Eight new MHC recombinant strains defining at least six H-2 haplotypes. Immunogenetics. 1986; 24(2):135-8.
    View in: PubMed
  571. Ildstad ST, Wren SM, Bluestone JA, Barbieri SA, Stephany D, Sachs DH. Effect of selective T cell depletion of host and/or donor bone marrow on lymphopoietic repopulation, tolerance, and graft-vs-host disease in mixed allogeneic chimeras (B10 + B10.D2----B10). J Immunol. 1986 Jan; 136(1):28-33.
    View in: PubMed
  572. Chatterjee-Das S, Schlauder GG, Sachs DH, Glimcher LH, Paul WE, McKean DJ. A biochemical analysis of Ak molecules from mutant antigen presenting cell lines. Immunogenetics. 1986; 23(2):121-5.
    View in: PubMed
  573. Sharp TA, Gress RE, Sachs DH, Rosenberg SA. Assessment of mixed lymphocyte reactivity in human bone marrow cell cultures. Transplantation. 1985 Nov; 40(5):551-6.
    View in: PubMed
  574. Devaux CA, Nadler PI, Miller GG, Sachs DH. Genetic control of immune response to staphylococcal nuclease. XII: Analysis of nuclease antigenic determinants using anti-nuclease monoclonal antibodies. Mol Cell Biochem. 1985 Sep; 68(1):31-40.
    View in: PubMed
  575. Rabinowitz R, Bluestone JA, Sachs DH. Evidence for a regulatory idiotypic network in the in vivo response to H-2 antigens. J Exp Med. 1985 Aug 1; 162(2):745-55.
    View in: PubMed
  576. Ildstad ST, Wren SM, Bluestone JA, Barbieri SA, Sachs DH. Characterization of mixed allogeneic chimeras. Immunocompetence, in vitro reactivity, and genetic specificity of tolerance. J Exp Med. 1985 Jul 1; 162(1):231-44.
    View in: PubMed
  577. Stroynowski I, Forman J, Goodenow RS, Schiffer SG, McMillan M, Sharrow SO, Sachs DH, Hood L. Expression and T cell recognition of hybrid antigens with amino-terminal domains encoded by Qa-2 region of major histocompatibility complex and carboxyl termini of transplantation antigens. J Exp Med. 1985 May 1; 161(5):935-52.
    View in: PubMed
  578. Melino MR, Epstein SL, Tse HY, Sachs DH, Hansen TH. Characterization of a dominant anti-Ia idiotype using the IA mutant mouse strain B6.C-H-2bm12. Mol Immunol. 1985 Apr; 22(4):417-26.
    View in: PubMed
  579. Pescovitz MD, Lunney JK, Sachs DH. Murine anti-swine T4 and T8 monoclonal antibodies: distribution and effects on proliferative and cytotoxic T cells. J Immunol. 1985 Jan; 134(1):37-44.
    View in: PubMed
  580. Ildstad ST, Wren SM, Sharrow SO, Stephany D, Sachs DH. In vivo and in vitro characterization of specific hyporeactivity to skin xenografts in mixed xenogeneically reconstituted mice (B10 + F344 rat----B10). J Exp Med. 1984 Dec 1; 160(6):1820-35.
    View in: PubMed
  581. Pescovitz MD, Thistlethwaite JR, Auchincloss H, Ildstad ST, Sharp TG, Terrill R, Sachs DH. Effect of class II antigen matching on renal allograft survival in miniature swine. J Exp Med. 1984 Nov 1; 160(5):1495-508.
    View in: PubMed
  582. Needleman BW, Pierres M, Devaux CA, Dwyer PN, Finnegan A, Sachs DH, Hodes RJ. An analysis of functional T cell recognition sites on I-E molecules. J Immunol. 1984 Aug; 133(2):589-96.
    View in: PubMed
  583. Pescovitz MD, Lunney JK, Sachs DH. Preparation and characterization of monoclonal antibodies reactive with porcine PBL. J Immunol. 1984 Jul; 133(1):368-75.
    View in: PubMed
  584. Bluestone JA, McKenzie IF, Melvold RW, Ozato K, Sandrin MS, Sharrow SO, Sachs DH. Serological analysis of H-2 mutations using monoclonal antibodies. J Immunogenet. 1984 Jun-Aug; 11(3-4):197-207.
    View in: PubMed
  585. Pescovitz MD, Sachs DH, Lunney JK, Hsu SM. Localization of class II MHC antigens on porcine renal vascular endothelium. Transplantation. 1984 Jun; 37(6):627-30.
    View in: PubMed
  586. Sharp TG, Sachs DH, Matthews JG, Maples J, Woody JN, Rosenberg SA. Harvest of human bone marrow directly from bone. J Immunol Methods. 1984 Apr 27; 69(2):187-95.
    View in: PubMed
  587. Lillehoj EP, Hansen TH, Sachs DH, Coligan JE. Primary structural evidence that the H-2Dq region encodes at least three distinct gene products: Dq, Lq, and Rq. Proc Natl Acad Sci U S A. 1984 Apr; 81(8):2499-503.
    View in: PubMed
  588. Thistlethwaite JR, Auchincloss H, Pescovitz MD, Sachs DH. Immunologic characterization of MHC recombinant swine: role of class I and II antigens in in vitro immune responses. J Immunogenet. 1984 Feb; 11(1):9-19.
    View in: PubMed
  589. Ildstad ST, Sachs DH. Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts. Nature. 1984 Jan 12-18; 307(5947):168-70.
    View in: PubMed
  590. Sharrow SO, Flaherty L, Sachs DH. Serologic cross-reactivity between Class I MHC molecules and an H-2-linked differentiation antigen as detected by monoclonal antibodies. J Exp Med. 1984 Jan 1; 159(1):21-40.
    View in: PubMed
  591. Miller GP, Sachs DH. Genetic control of the immune response to staphylococcal nuclease. X. Isoelectric focusing spectrotypes of antinuclease antibodies detected by labeling with antigen and with anti-idiotype. Mol Cell Biochem. 1984; 60(2):137-45.
    View in: PubMed
  592. Osborne BA, Lunney JK, Pennington L, Sachs DH, Rudikoff S. Two-dimensional gel analysis of swine histocompatibility antigens. J Immunol. 1983 Dec; 131(6):2939-44.
    View in: PubMed
  593. Auchincloss H, Sachs DH. Mechanisms of tolerance in murine radiation bone marrow chimeras. II. Absence of nonspecific suppression in mature chimeras. Transplantation. 1983 Oct; 36(4):442-5.
    View in: PubMed
  594. Auchincloss H, Sachs DH. Mechanisms of tolerance in murine radiation bone marrow chimeras. I. Nonspecific suppression of alloreactivity by spleen cells from early, but not late, chimeras. Transplantation. 1983 Oct; 36(4):436-41.
    View in: PubMed
  595. Melino MR, Epstein SL, Sachs DH, Hansen TH. Idiotypic and fluorometric analysis of the antibodies that distinguish the lesion of the I-A mutant B6.C-H-2bm12. J Immunol. 1983 Jul; 131(1):359-64.
    View in: PubMed
  596. Bluestone JA, Auchincloss H, Sachs DH, Fibi M, Hämmerling GJ. Anti-idiotypes against anti-H-2 antibodies VI. Detection of shared idiotypes among monoclonal anti-H-2 antibodies. Eur J Immunol. 1983 Jun; 13(6):489-95.
    View in: PubMed
  597. Lunney JK, Osborne BA, Sharrow SO, Devaux C, Pierres M, Sachs DH. Sharing of Ia antigens between species. IV. Interspecies cross-reactivity of monoclonal antibodies directed against polymorphic mouse Ia determinants. J Immunol. 1983 Jun; 130(6):2786-93.
    View in: PubMed
  598. Glimcher LH, Hamano T, Asofsky R, Sachs DH, Pierres M, Samelson LE, Sharrow SO, Paul WE. IA mutant functional antigen-presenting cell lines. J Immunol. 1983 May; 130(5):2287-94.
    View in: PubMed
  599. Auchincloss H, Bluestone JA, Sachs DH. Antiidiotypes against anti-H-2 monoclonal antibodies. V. In vivo antiidiotype treatment induces idiotype-specific helper T cells. J Exp Med. 1983 Apr 1; 157(4):1273-86.
    View in: PubMed
  600. Thistlethwaite JR, Pennington LR, Lunney JK, Sachs DH. Immunologic characterization of MHC recombinant swine. Production of SLA class specific antisera and detection of Ia antigens on both B and non-B PBL. Transplantation. 1983 Apr; 35(4):394-400.
    View in: PubMed
  601. Almaraz R, Ballinger W, Sachs DH, Rosenberg SA. The effect of peripheral lymphoid cells on the incidence of lethal graft versus host disease following allogeneic mouse bone marrow transplantation. J Surg Res. 1983 Feb; 34(2):133-44.
    View in: PubMed
  602. Sharp TG, Sachs DH, Fauci AS, Messerschmidt GL, Rosenberg SA. T cell depletion of human bone marrow using monoclonal antibody and complement-mediated lysis. Transplantation. 1983 Feb; 35(2):112-20.
    View in: PubMed
  603. Sacks DL, Kelsoe GH, Sachs DH. Induction of immune responses with anti-idiotypic antibodies: implications for the induction of protective immunity. Springer Semin Immunopathol. 1983; 6(1):79-97.
    View in: PubMed
  604. Hansen TH, Ozato K, Sachs DH. Heterogeneity of H-2D region associated genes and gene products. Adv Immunol. 1983; 34:39-70.
    View in: PubMed
  605. Ozato K, Epstein SL, Bluestone JA, Sharrow SO, Hansen T, Sachs DH. The presence of a common idiotype in anti-H-2 immune sera as detected by anti-idiotype to a monoclonal anti-H-2 antibody. Eur J Immunol. 1983 Jan; 13(1):13-8.
    View in: PubMed
  606. Sachs DH, Bluestone JA, Epstein SL, Rabinowitz R. Idiotypes of anti-major histocompatibility complex antibodies. Ann N Y Acad Sci. 1983; 418:265-71.
    View in: PubMed
  607. Klein J, David CS, Démant P, Hämmerling G, McKenzie IF, Murphy DB, Sachs DH, Tada T. Revised rules for naming class I and class II antigenic determinants controlled by the mouse H-2 complex. Immunogenetics. 1983; 17(6):597-8.
    View in: PubMed
  608. Arn JS, Riordan SE, Pearson D, Sachs DH. Strain restricted typing sera (SRTS) for use in monitoring the genetic integrity of congenic strains. J Immunol Methods. 1982 Dec 17; 55(2):141-53.
    View in: PubMed
  609. Bluestone JA, Krutzsch HC, Auchincloss H, Cazenave PA, Kindt TJ, Sachs DH. Anti-idiotypes against anti-H-2 monoclonal antibodies: structural analysis of the molecules induced by in vivo anti-idiotype treatment. Proc Natl Acad Sci U S A. 1982 Dec; 79(24):7847-51.
    View in: PubMed
  610. Bluestone JA, Auchincloss H, Cazenave PA, Ozato K, Sachs DH. Anti-idiotypes to monoclonal anti-H-2 antibodies. III. Syngeneic anti-idiotypes on antibodies induced by in vivo administration of xenogeneic anti-idiotypes. J Immunol. 1982 Nov; 129(5):2066-8.
    View in: PubMed
  611. Devaux C, Epstein SL, Sachs DH, Pierres M. Cross-reactive idiotypes of monoclonal anti-Iak antibodies: characterization with xenogeneic anti-idiotypic reagents and expression in anti-H-2 humoral responses. J Immunol. 1982 Nov; 129(5):2074-81.
    View in: PubMed
  612. Epstein SL, Masakowski VR, Sharrow SO, Bluestone JA, Ozato K, Sachs DH. Idiotypes of anti-Ia antibodies. II. Effects of in vivo treatment with xenogeneic anti-idiotype. J Immunol. 1982 Oct; 129(4):1545-52.
    View in: PubMed
  613. Ozato K, Mayer NM, Sachs DH. Monoclonal antibodies to mouse major histocompatibility complex antigens. Transplantation. 1982 Sep; 34(3):113-20.
    View in: PubMed
  614. Metzger JJ, Lunney JK, Sachs DH, Rudikoff S. Transplantation in miniature swine. XII. N-terminal sequences of class I histocompatibility antigens (SLA) and beta 2-microglobulin. J Immunol. 1982 Aug; 129(2):716-21.
    View in: PubMed
  615. Auchincloss H, Ozato K, Sachs DH. A monoclonal antibody detecting unusual Thy-1 determinants. J Immunol. 1982 Apr; 128(4):1584-9.
    View in: PubMed
  616. Bluestone JA, Metzger JJ, Knode MC, Ozato K, Sachs DH. Anti-idiotypes to monoclonal anti-H-2 antibodies--I. Contribution of isolated heavy and light chains to idiotype expression. Mol Immunol. 1982 Apr; 19(4):515-24.
    View in: PubMed
  617. Singer DS, Camerini-Otero RD, Satz ML, Osborne B, Sachs D, Rudikoff S. Characterization of a porcine genomic clone encoding a major histocompatibility antigen: expression in mouse L cells. Proc Natl Acad Sci U S A. 1982 Mar; 79(5):1403-7.
    View in: PubMed
  618. Ozato K, Sachs DH. Detection of at least two distinct mouse I-E antigen molecules by the use of a monoclonal antibody. J Immunol. 1982 Feb; 128(2):807-10.
    View in: PubMed
  619. Nadler PI, Miller GG, Sachs DH, Hodes RJ. The expression and functional involvement of nuclease- specific idiotype on nuclease-primed helper T cells. Eur J Immunol. 1982 Feb; 12(2):113-20.
    View in: PubMed
  620. Miller GG, Nadler PI, Hodes RJ, Sachs DH. Modification of T cell antinuclease idiotype expression by in vivo administration of anti-idiotype. J Exp Med. 1982 Jan 1; 155(1):190-200.
    View in: PubMed
  621. Hansen TH, Walsh WD, Ozato K, Arn JS, Sachs DH. Ia specificities on parental and hybrid cells of an I-A mutant mouse strain. J Immunol. 1981 Dec; 127(6):2228-31.
    View in: PubMed
  622. Hurtenbach U, Sachs DH, Shearer GM. Protection against graft vs. host-associated immunosuppression in F1 mice. I. Activation of F1 regulatory cells by host-specific anti-major histocompatibility complex antibodies. J Exp Med. 1981 Dec 1; 154(6):1922-34.
    View in: PubMed
  623. Berzofsky JA, Pisetsky DS, Killion DJ, Hicks G, Sachs DH. Ir genes of different high responder haplotypes for staphylococcal nuclease are not allelic. J Immunol. 1981 Dec; 127(6):2453-5.
    View in: PubMed
  624. Bluestone JA, Epstein SL, Ozato K, Sharrow SO, Sachs DH. Anti-idiotypes to monoclonal anti-H-2 antibodies. II. Expression of anti-H-2Kk idiotypes on antibodies induced by anti-idiotype or H-2Kk antigen. J Exp Med. 1981 Nov 1; 154(5):1305-18.
    View in: PubMed
  625. Auchincloss H, Ozato K, Sachs DH. Two distinct murine differentiation antigens determined by genes linked to the Ly-6 locus. J Immunol. 1981 Nov; 127(5):1839-43.
    View in: PubMed
  626. Pennington LR, Flye MW, Kirkman RL, Thistlethwaite JR, Williams GM, Sachs DH. Transplantation in miniature swine. X. Evidence for non-SLA-linked immune response gene(s) controlling rejection of SLA-matched kidney allografts. Transplantation. 1981 Oct; 32(4):315-20.
    View in: PubMed
  627. Metzger JJ, Gilliland GL, Lunney JK, Osborne BA, Rudikoff S, Sachs DH. Transplantation in miniature swine. IX. Swine histocompatibility antigens: isolation and purification of papain-solubilized SLA antigens. J Immunol. 1981 Aug; 127(2):769-75.
    View in: PubMed
  628. Epstein SL, Ozato K, Bluestone JA, Sachs DH. Idiotypes of anti-Ia antibodies. I. Expression of the 14-4-4S idiotype in humoral immune responses. J Exp Med. 1981 Aug 1; 154(2):397-409.
    View in: PubMed
  629. Shinohara N, Sachs DH, Nonaka N, Yamamoto H. Phylogenetic tracing of Ia genes. Nature. 1981 Jul 23; 292(5821):362-3.
    View in: PubMed
  630. Miller GG, Nadler PI, Asano Y, Hodes RJ, Sachs DH. Induction of idiotype-bearing, nuclease-specific helper T cells by in vivo treatment with anti-idiotype. J Exp Med. 1981 Jul 1; 154(1):24-34.
    View in: PubMed
  631. Sachs DH, El-Gamil M, Miller G. Genetic control of the immune response to staphylococcal nuclease. XI. Effects of in vivo administration of anti-idiotypic antibodies. Eur J Immunol. 1981 Jun; 11(6):509-16.
    View in: PubMed
  632. Bluestone JA, Sharrow SO, Epstein SL, Ozato K, Sachs DH. Induction of anti-H-2 antibodies without alloantigen exposure by in vivo administration of anti-idiotype. Nature. 1981 May 21; 291(5812):233-5.
    View in: PubMed
  633. Ozato K, Henkart P, Jensen C, Sachs DH. Spatially distinct allodeterminants of the H-2Kk molecule as detected by monoclonal anti-H-2 antibodies. J Immunol. 1981 May; 126(5):1780-5.
    View in: PubMed
  634. Hansen TH, Ozato K, Melino MR, Coligan JE, Kindt TJ, Jandinski JJ, Sachs DH. Immunochemical evidence in two haplotypes for at least three D region-encoded molecules, D, L, and R. J Immunol. 1981 May; 126(5):1713-6.
    View in: PubMed
  635. Nadler PI, Miller GP, Sachs DH, Hodes RJ. Genetic control of antibody responses to TNP-nuclease in vitro. J Immunol. 1981 May; 126(5):1706-12.
    View in: PubMed
  636. Sachs DH, el-Gamil M, Arn JS, Ozato K. Complementation between I region genes is revealed by a hybridoma anti-Ia antibody. Transplantation. 1981 Apr; 31(4):308-10.
    View in: PubMed
  637. Shinohara N, Sachs DH. Evidence for homologues of the murine I-A and I-E loci in the rat MHC. J Immunol. 1981 Mar; 126(3):934-7.
    View in: PubMed
  638. Sachs DH, Bluestone JA, Epstein SL, Ozato K. Antiidiotypes to monoclonal anti-H-2 and anti-Ia hybridoma antibodies. Transplant Proc. 1981 Mar; 13(1 Pt 2):953-7.
    View in: PubMed
  639. Ozato K, Epstein SL, Henkart P, Hansen TH, Sachs DH. Studies on monoclonal antibodies to mouse MHC products. Transplant Proc. 1981 Mar; 13(1 Pt 2):958-62.
    View in: PubMed
  640. Ozato K, Sachs DH. Monoclonal antibodies to mouse MHC antigens. III. Hybridoma antibodies reacting to antigens of the H-2b haplotype reveal genetic control of isotype expression. J Immunol. 1981 Jan; 126(1):317-21.
    View in: PubMed
  641. Pennington LR, Lunney JK, Sachs DH. Transplantation in miniature swine. VIII. Recombination within the major histocompatibility complex of miniature swine. Transplantation. 1981 Jan; 31(1):66-71.
    View in: PubMed
  642. Ozato K, Hansen TH, Sachs DH. Monoclonal antibodies to mouse MHC antigens. II. Antibodies to the H-2Ld antigen, the products of a third polymorphic locus of the mouse major histocompatibility complex. J Immunol. 1980 Dec; 125(6):2473-7.
    View in: PubMed
  643. Sharrow SO, Ozato K, Sachs DH. Phenotypic expression of I-A and I-E/C subregion determinants on murine thymocytes. J Immunol. 1980 Nov; 125(5):2263-8.
    View in: PubMed
  644. Shinohara N, Hämmerling U, Sachs DH. Mouse alloantibodies capable of blocking cytotoxic T cell function. II. Further study on the relationship between the blocking antibodies and the products of the Lyt-2 locus. Eur J Immunol. 1980 Aug; 10(8):589-94.
    View in: PubMed
  645. Ozato K, Lunney JK, El-Gamil M, Sachs DH. Evidence for the absence of I-E/C antigen expression on the cell surface in mice of the H-2b or H-2s haplotypes. J Immunol. 1980 Aug; 125(2):940-5.
    View in: PubMed
  646. Epstein SL, Ozato K, Sachs DH. Blocking of allogeneic cell-mediated lympholysis by monoclonal antibodies to H-2 antigens. J Immunol. 1980 Jul; 125(1):129-35.
    View in: PubMed
  647. Johnson H, Lunney JK, Sachs DH, Flye MW. Preparation and characterization of an antiserum specific for T cells of pigs. Transplantation. 1980 Jun; 29(6):477-83.
    View in: PubMed
  648. Hansen TH, Melvold RW, Arn JS, Sachs DH. Evidence for mutation in an I-A gene. Nature. 1980 May 29; 285(5763):340-1.
    View in: PubMed
  649. Hansen TH, Ozato K, Sachs DH. Enumeration of H-2-gene products: failure to detect L molecules in the H-2b haplotype. Ann Immunol (Paris). 1980 May-Jun; 131C(3):327-34.
    View in: PubMed
  650. Krakauer T, Hansen TH, Camerini-Otero RD, Sachs DH. Analysis of the heterogeneity of the mouse H-2K, D, and L gene products. J Immunol. 1980 May; 124(5):2149-56.
    View in: PubMed
  651. Sachs DH, Kiszkiss P, Kim KJ. Release of Ia antigens by a cultured B cell line. J Immunol. 1980 May; 124(5):2130-6.
    View in: PubMed
  652. Ozato K, Mayer N, Sachs DH. Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens. J Immunol. 1980 Feb; 124(2):533-40.
    View in: PubMed
  653. Coligan JE, Kindt TJ, Nairn R, Nathenson SG, Sachs DH, Hansen TH. Primary structural studies of an H-2L molecule confirm that it is a unique gene product with homology to H-2K and H-2D antigens. Proc Natl Acad Sci U S A. 1980 Feb; 77(2):1134-8.
    View in: PubMed
  654. Dickler HB, Rosenstreich DL, Ahmed A, Sachs DH. Genetic linkage between Lym-1, Sas-1 and Mls loci. Immunogenetics. 1980; 10(1):93-6.
    View in: PubMed
  655. Sachs DH. An overview and recent findings on the Ia antigens of the major histocompatibility locus. J Reticuloendothel Soc. 1979 Dec; 26(Suppl):581-6.
    View in: PubMed
  656. Kanellopoulos-Langevin C, Kim KJ, Sachs DH, Asofsky R. Relationship between Fc (IgG) receptors and alloantigens on the surface of BALB/c B cell lymphoma lines. J Immunol. 1979 Dec; 123(6):2651-7.
    View in: PubMed
  657. Katz SI, Tamaki K, Sachs DH. Epidermal Langerhans cells are derived from cells originating in bone marrow. Nature. 1979 Nov 15; 282(5736):324-6.
    View in: PubMed
  658. Sachs DH, Arn JS, Hansen TH. Two new recombinant H-2 haplotypes, one of which juxtaposes Kb and Ik alleles. J Immunol. 1979 Nov; 123(5):1965-9.
    View in: PubMed
  659. Mond JJ, Sehgal E, Sachs DH, Paul WE. Expression of Ia antigen on adult and neonatal B lymphocytes responsive to thymus-independent antigens. J Immunol. 1979 Oct; 123(4):1619-23.
    View in: PubMed
  660. Hansen TH, Ivanyi P, Levy RB, Sachs DH. Cross-reactivity among the products of three nonallelic H-2 loci, H-2Ld, H-2Dq, and H-2Kk. Transplantation. 1979 Oct; 28(4):339-42.
    View in: PubMed
  661. Shinohara N, Sachs DH. Mouse alloantibodies capable of blocking cytotoxic T-cell function. I. Relationship between the antigen reactive with blocking antibodies and the Lyt-2 locus. J Exp Med. 1979 Sep 19; 150(3):432-44.
    View in: PubMed
  662. Tamaki K, Stingl G, Gullino M, Sachs DH, Katz SI. Ia antigens in mouse skin are predominantly expressed on Langerhans cells. J Immunol. 1979 Aug; 123(2):784-7.
    View in: PubMed
  663. Kirkman RL, Colvin RB, Flye MW, Leight GS, Rosenberg SA, Williams GM, Sachs DH. Transplantation in miniature swine. VI. Factors influencing survival of renal allografts. Transplantation. 1979 Jul; 28(1):18-23.
    View in: PubMed
  664. Kirkman RL, Colvin RB, Flye MW, Williams GM, Sachs DH. Transplantation in miniature swine. VII. Evidence for cellular immune mechanisms in hyperacute rejection of renal alografts. Transplantation. 1979 Jul; 28(1):24-30.
    View in: PubMed
  665. Pisetsky DS, Riordan SE, Sachs DH. Genetic control of the immune response to staphylococcal nuclease. IX. Recombination between genes determining BALB/c antinuclease idiotypes and the heavy chain allotype locus. J Immunol. 1979 Mar; 122(3):842-6.
    View in: PubMed
  666. Sachs DH. Ia antigens. Transplant Proc. 1979 Mar; 11(1):1167-9.
    View in: PubMed
  667. Kirkman RL, Flye MW, Williams GM, Colvin RB, Sachs DH. Evidence for cellular immune mechanisms in hyperacute rejection of renal allografts in miniature swine. Transplant Proc. 1979 Mar; 11(1):790-2.
    View in: PubMed
  668. Lunney JK, Sachs DH. Transplantation in miniature swine. V. Characterization of Ia antigens. J Immunol. 1979 Feb; 122(2):623-7.
    View in: PubMed
  669. Skamene E, Kongshavn PA, Sachs DH. Resistance to Listeria monocytogenes in mice: genetic control by genes that are not linked to the H-2 complex. J Infect Dis. 1979 Feb; 139(2):228-31.
    View in: PubMed
  670. Kim KJ, Kanellopoulos-Langevin C, Merwin RM, Sachs DH, Asofsky R. Establishment and characterization of BALB/c lymphoma lines with B cell properties. J Immunol. 1979 Feb; 122(2):549-54.
    View in: PubMed
  671. Lunney JK, Mann DL, Sachs DH. Sharing Ia antigens between species. III. Ia specificities shared between mice and human beings. Scand J Immunol. 1979; 10(5):403-13.
    View in: PubMed
  672. Shinohara N, Hansen TH, Schurko E, McKenzie IF, Sachs DH. Genetic control of the immune response to the H-2Dk private specificity, H-2.32. II. Genetic linkage analysis of a backcross generation. J Immunol. 1978 Dec; 121(6):2472-6.
    View in: PubMed
  673. Ahmann GB, Sachs DH, Hodes RJ. Requirement for an Ia-bearing accessory cell in Con A-induced T cell proliferation. J Immunol. 1978 Nov; 121(5):1981-9.
    View in: PubMed
  674. Cowing C, Pincus SH, Sachs DH, Dickler HB. A subpopulation of adherent accessory cells bearing both I-A and I-E or C subregion antigens is required for antigen-specific murine T lymphocyte proliferation. J Immunol. 1978 Nov; 121(5):1680-6.
    View in: PubMed
  675. Hansen TH, Sachs DH. Isolation and antigenic characterization of the product of a third polymorphic H-2 locus, H-2L. J Immunol. 1978 Oct; 121(4):1469-72.
    View in: PubMed
  676. Pincus SH, Sachs DH, Dickler HB. Production of antisera specific for idiotype(s) of murine anti-(T,G)-A--L antibodies. J Immunol. 1978 Oct; 121(4):1422-7.
    View in: PubMed
  677. Shinohara N, Lunney JK, Sachs DH. Sharing of Ia antigens between species. II. Molecular localization of shared Ia determinants implies the existence of more than one I sublocus of the rat MHC. J Immunol. 1978 Aug; 121(2):637-40.
    View in: PubMed
  678. Leight GS, Kirkman R, Rasmusen BA, Rosenberg SA, Sachs DH, Terrill R, Williams GM. Transplantation in miniature swine. III: effects of MSLA and A-O blood group matching on skin allograft survival. Tissue Antigens. 1978 Aug; 12(2):65-74.
    View in: PubMed
  679. Ahmann GB, Sachs DH, Hodes RJ. Genetic analysis of Ia determinants expressed on Con A-reactive cells. J Immunol. 1978 Jul; 121(1):159-65.
    View in: PubMed
  680. Schwartz RH, Berzofsky JA, Horton CL, Schechter AN, Sachs DH. Genetic control of the T lymphocyte proliferative response to staphylococcal nuclease: evidence for multiple MHC-linked Ir gene control. J Immunol. 1978 May; 120(5):1741-9.
    View in: PubMed
  681. Pisetsky DS, Sachs DH. Genetic control of the immune response to staphylococcal nuclease. VIII. Mapping of genes for antibodies to different antigenic regions of nuclease. J Exp Med. 1978 May 1; 147(5):1517-25.
    View in: PubMed
  682. Pisetsky DS, Berzofsky JA, Sachs DH. Genetic control of the immune response to staphylococcal nuclease. VII. Role of non-H2-linked genes in the control of the anti-nuclease antibody response. J Exp Med. 1978 Feb 1; 147(2):396-408.
    View in: PubMed
  683. Lunney JK, Sachs DH. Transplantation in minature swine. IV. Chemical characterization of MSLA and Ia-like antigens. J Immunol. 1978 Feb; 120(2):607-12.
    View in: PubMed
  684. Berzofsky JA, Pisetsky DS, Schwartz RH, Schechter AN, Sachs DH. Genetic control of the immune response to staphylococcal nuclease in mice. Adv Exp Med Biol. 1978; 98:241-57.
    View in: PubMed
  685. Dickles HB, Ahmed A, Sachs DH. B-lymphocyte Fc receptor-associated non-H-2 antigens are determined by a single polymorphic locus which is linked to the Mls locus. J Exp Med. 1977 Dec 1; 146(6):1678-92.
    View in: PubMed
  686. Pisetsky DS, Sachs DH. The genetic control of the immune response to staphylococcal nuclease VI. Recombination between genes determining the A/J anti-nuclease idiotypes and the heavy chain allotype locus. J Exp Med. 1977 Dec 1; 146(6):1603-12.
    View in: PubMed
  687. Shinohara N, Ricks J, Hansen TH, Sachs DH. Genetic control of immune response to the H-2Dk private specificity, H-2.32. I. Low responsiveness of the B10 congenic mice to the H-2.32 determinant. J Immunol. 1977 Nov; 119(5):1732-7.
    View in: PubMed
  688. Nelson DL, Sachs DH, Dickler HB. Antibody-dependent cellular cytotoxicity effector cells lack Ia antigens. J Immunol. 1977 Sep; 119(3):1034-40.
    View in: PubMed
  689. Sachs DH, Humphrey GW, Lunney JK. Sharing of Ia antigens between species. I. Detection of Ia specificities shared by rats and mice. J Exp Med. 1977 Aug 1; 146(2):381-93.
    View in: PubMed
  690. Hansen TH, Cullen SE, Melvold R, Kohn H, Flaherty L, Sachs DH. Mutation in a new H-2-associated histocompatibility gene closely linked to H-2D. J Exp Med. 1977 Jun 1; 145(6):1550-8.
    View in: PubMed
  691. Shinohara N, Cullen SE, Sachs DH. Ag-B-linked analogue of Ia antigens in the rat. J Immunol. 1977 Jun; 118(6):2083-7.
    View in: PubMed
  692. Hansen TH, Cullen SE, Shinohara N, Schurko E, Sachs DH. Genetic control of the humoral response to an H-2 public specificity. J Immunol. 1977 Apr; 118(4):1403-8.
    View in: PubMed
  693. Leight GS, Sachs DH, Williams GM, Rosenberg SA. Transplantation in miniature swine. Transplant Proc. 1977 Mar; 9(1):575-7.
    View in: PubMed
  694. Leight GS, Sachs DH, Rosenberg SA. Transplantation in miniature swine. II. In vitro parameters of histocompatibility in MSLA homozygous minipigs. Transplantation. 1977 Mar; 23(3):271-6.
    View in: PubMed
  695. Neefe JR, Sachs DH. Adherence properties of cytotoxic cells and their precursors on spleen cell monolayers. Transplant Proc. 1977 Mar; 9(1):797-9.
    View in: PubMed
  696. Fathman CG, Pisetsky DS, Sachs DH. Genetic control of the immune response to nuclease. V. Genetic linkage and strain distribution of anti-nuclease idiotypes. J Exp Med. 1977 Mar 1; 145(3):569-77.
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  697. Neefe JR, Sachs DH. Specific elimination of cytotoxic cells. II. Reduction of cytotoxic activity by adsorption on monolayers results from removal of cytotoxic cells and not from inhibition of their activity. Cell Immunol. 1977 Mar 1; 29(1):129-36.
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  698. Hansen TH, Cullen SE, Sachs DH. Immunochemical evidence for an additional H-2 region closely linked to H-2D. J Exp Med. 1977 Feb 1; 145(2):438-42.
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  699. Berzofsky JA, Schechter AN, Shearer GM, Sachs DH. Genetic control of the immune response to staphylococcal nuclease. IV. H-2-linked control of the relative proportions of antibodies produced to different determinants of native nuclease. J Exp Med. 1977 Jan 1; 145(1):123-35.
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  700. Sachs DH, Berzofsky JA, Fathman CG, Pisetsky DS, Schechter AN, Schwartz RH. The immune response to staphylococcal nuclease: a probe of cellular and humoral antigen-specific receptors. Cold Spring Harb Symp Quant Biol. 1977; 41 Pt 1:295-306.
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  701. Ahmed A, Scher I, Sharrow SO, Smith AH, Paul WE, Sachs DH, Sell KW. B-lymphocyte heterogeneity: development and characterization of an alloantiserum which distinguishes B-lymphocyte differentiation alloantigens. J Exp Med. 1977 Jan 1; 145(1):101-10.
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  702. Berzofsky JA, Schechter AN, Shearer GM, Sachs DH. Genetic control of the immune response to staphylococcal nuclease. III. Time-course and correlation between the response to native nuclease and the response to its polypeptide fragments. J Exp Med. 1977 Jan 1; 145(1):111-22.
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  703. Sachs DH, Leight G, Cone J, Schwarz S, Stuart L, Rosenberg S. Transplantation in miniature swine. I. Fixation of the major histocompatibility complex. Transplantation. 1976 Dec; 22(6):559-67.
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  704. Neefe JR, Sachs DH. Specific elimination of cytotoxic effector cells. I. Adsorptive behavior of effectors and their precursors and spleen cell monolayers. J Exp Med. 1976 Oct 1; 144(4):996-1008.
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  705. Channing CP, Tsai V, Sachs D. Role of insulin, thyroxin and cortisol in luteinization of porcine granulosa cells grown in chemically defined media. Biol Reprod. 1976 Sep; 15(2):235-47.
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  706. Sachs DH, Cone JL, Humphrey GW. The humoral response to an Ia antigen and skin graft rejection: mechanistic possibilities. Transplant Proc. 1976 Sep; 8(3):413-6.
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  707. Schwartz RH, David CS, Sachs DH, Paul WE. T lymphocyte-enriched murine peritoneal exudate cells. III. Inhibition of antigen-induced T lymphocyte Proliferation with anti-Ia antisera. J Immunol. 1976 Aug; 117(2):531-40.
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  708. Sachs DH, Duffy KG. Effect of modeling on sexual imagery. Arch Sex Behav. 1976 Jul; 5(4):269-74.
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  709. Dickler HB, Arbeit RD, Henkart PA, Sachs DH. Association between Ia antigens and the Fc receptors of certain T lymphocytes. J Exp Med. 1976 Jul 1; 144(1):282-7.
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  710. Fathman CG, Sachs DH. Genetic control of the immune response to nuclease. II. Detection of idiotypic determinants by the inhibition of antibody-mediated nuclease inactivation. J Immunol. 1976 Apr; 116(4):959-64.
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  711. Schwartz RH, Fathman CG, Sachs DH. Inhibition of stimulation in murine mixed lymphocyte cultures with an alloantiserum directed against a shared Ia determinant. J Immunol. 1976 Apr; 116(4):929-35.
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  712. Cullen SE, David CS, Cone JL, Sachs DH. Evidence for more than one Ia antigenic specificity on molecules determined by the I-A subregion of the mouse major histocompatibility complex. J Immunol. 1976 Feb; 116(2):549-53.
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  713. Schmitt-Verhulst AM, Sachs DH, Shearer GM. Cell-mediated lympholysis of trinitrophenyl-modified autologous lymphocytes. Confirmation of genetic control of response to trinitrophenyl-modified H-2 antigens by the use of anti-H-2 and anti-Ia antibodies. J Exp Med. 1976 Jan 1; 143(1):211-7.
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  714. Schwartz RH, Dickler HB, Sachs DH, Schwartz BD. Studies of Ia antigens on murine peritoneal macrophages. Scand J Immunol. 1976; 5(6-7):731-43.
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  715. Sachs DH. The Ia antigens. Contemp Top Mol Immunol. 1976; 5:1-33.
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  716. Arbeit RD, Sachs DH, Amos DB, Dickler HB. Human lymphocyte alloantigen(s) similar to murine Ir region-associated (Ia) antigens. J Immunol. 1975 Oct; 115(4):1173-5.
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  717. Dickler HB, Cone JL, Kubicek MT, Sachs DH. Detection of non-H2 antigen(s) which, like Ia antigens, are associated with the Fc receptor of B lymphocytes. J Exp Med. 1975 Sep 1; 142(3):796-801.
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  718. Fathman CG, Cone JL, Sharrow SO, Tyrer H, Sachs DH. Ia alloantigen(s) detected on thymocytes by use of a fluorescence-activated cell sorter. J Immunol. 1975 Aug; 115(2):584-9.
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  719. Sachs DH, Cullen SE, David CS. Ir-associated murine alloantigens. Serological and chemical definition of Ia specificities associated with the H-2-b haplotype. Transplantation. 1975 May; 19(5):388-93.
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  720. Furie B, Schechter AN, Sachs DH, Anfinsen CB. An immunological approach to the conformational equilibrium of staphylococcal nuclease. J Mol Biol. 1975 Mar 15; 92(4):497-506.
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  721. Sachs DH, Cone JL. Ir-associated murine alloantigens: demonstration of multiple Ia specificities in H-2 alloantisera after selective absorptions. J Immunol. 1975 Jan; 114(1 Pt 1):165-9.
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  722. Sachs DH, Dickler HB. The possible role of i region determined cell surface molecules in the regulation of immune responses. Transplant Rev. 1975; 23:159-75.
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  723. Armerding D, Sachs DH, Katz DH. Activation of T and B lymphocytes in vitro. III. Presence of Ia determinants on allogeneic effect factor. J Exp Med. 1974 Dec 1; 140(6):1717-22.
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  724. Sachs DH, Schecter AN, Eastlake A, Anfinsen CB. Immunological distinction between the possible origins of enzymatic activity in a polypeptide fragment of staphylococcal nuclease. Nature. 1974 Sep 20; 251(5472):242-4.
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  725. Dickler HB, Sachs DH. Evidence for identity or close association of the Fc receptor of B lymphocytes and alloantigens determined by the Ir region of the H-2 complex. J Exp Med. 1974 Sep 1; 140(3):779-96.
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  726. Fathman CG, Handwerger BS, Sachs DH. Evidence for a role of Ir-associated alloantigens in mixed lymphocyte culture stimulation. J Exp Med. 1974 Sep 1; 140(3):853-8.
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  727. Schechter B, Sachs DH, Terry WD. Suppression of protein synthesis as a measure of humoral and cellular cytotoxicity. Transplantation. 1974 Sep; 18(3):267-72.
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  728. Gelfand MC, Sachs DH, Lieberman R, Paul WE. Ontogeny of B lymphocytes. 3. H-2 linkage of a gene controlling the rate of appearance of complement receptor lymphocytes. J Exp Med. 1974 May 1; 139(5):1142-53.
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  729. Lozner EC, Sachs DH, Shearer GM. Genetic control of the immune response to staphylococcal nuclease. I. Ir-Nase: control of the antibody response to nuclease by the Ir region of the mouse H-2 complex. J Exp Med. 1974 May 1; 139(5):1204-14.
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  730. Eastlake A, Sachs DH, Schechter AN, Anfinsen CB. Binding of univalent antibody fragments to a distinct antigenic determinant of staphylococcal nuclease. Biochemistry. 1974 Apr 9; 13(8):1567-71.
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  731. Furie B, Schechter AN, Sachs DH, Anfinsen CB. Antibodies to the unfolded form of a helix-rich region in staphylococcal nuclease. Biochemistry. 1974 Apr 9; 13(8):1561-6.
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  732. Lozner EC, Sachs DH, Shearer GM, Terry WD. B-cell alloantigens determined by the H-2 linked Ir region are associated with mixed lymphocyte culture stimulation. Science. 1974 Feb 22; 183(4126):757-9.
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  733. Sachs DH, Cone JL. A mouse B-cell alloantigen determined by gene(s) linked to the major histocompatibility complex. J Exp Med. 1973 Dec 1; 138(6):1289-304.
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  734. Sachs DH, McKenzie IF, Winn HJ, Russell PS. Serologic distinction between soluble species-specific and strain-specific transplantation antigens. Transplant Proc. 1973 Mar; 5(1):477-80.
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  735. Sachs DH, Schechter AN, Eastlake A, Anfinsen CB. An immunologic approach to the conformational equilibria of polypeptides. Proc Natl Acad Sci U S A. 1972 Dec; 69(12):3790-4.
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  736. Sachs DH, Schechter AN, Eastlake A, Anfinsen CB. Antibodies to a distinct antigenic determinant of staphylococcal nuclease. J Immunol. 1972 Dec; 109(6):1300-10.
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  737. Sachs DH, Schechter AN, Eastlake A, Anfinsen CB. Inactivation of staphylococcal nuclease by the binding of antibodies to a distinct antigenic determinant. Biochemistry. 1972 Nov 7; 11(23):4268-73.
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  738. Schechter AN, Sachs DH, Heller SR, Shrager RI, Cohen JS. Nuclear magnetic resonance titration curves of histidine ring protons. 3. Ribonuclease. J Mol Biol. 1972 Oct 28; 71(1):39-48.
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  739. Corley L, Sachs DH, Anfinsen CB. Rapid solid-phase synthesis of bradykinin. Biochem Biophys Res Commun. 1972 Jun 28; 47(6):1353-9.
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  740. Sachs DH, Painter E. Improved flow rates with porous sephadex gels. Science. 1972 Feb 18; 175(4023):781-2.
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  741. Shrager RI, Cohen JS, Heller SR, Sachs DH, Schechter AN. Mathematical models for interacting groups in nuclear magnetic resonance titration curves. Biochemistry. 1972 Feb 15; 11(4):541-7.
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  742. Sachs DH, Schechter AN, Cohen JS. Nuclear magnetic resonance titration curves of histidine ring protons. I. Influence of neighboring charged groups. J Biol Chem. 1971 Nov; 246(21):6576-80.
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  743. Sachs DH, Winn HJ, Russell PS. The immunologic response to xenografts. Recognition of mouse H-2 histocompatibility antigens by the rat. J Immunol. 1971 Aug; 107(2):481-92.
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  744. Sachs DH, Winn HJ, Russell PS. Histocompatibility relationships between species. Transplant Proc. 1971 Mar; 3(1):210-3.
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  745. Koene R, McKenzie IF, Painter E, Sachs DH, Winn HJ, Russell PS. Soluble mouse histocompatibility antigens. Transplant Proc. 1971 Mar; 3(1):231-3.
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  746. Sachs DH, Winn HJ. The use of glutaraldehyde as a coupling agent for ribonuclease and bovine serum albumin. Immunochemistry. 1970 Jun; 7(6):581-5.
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  747. Sachs DH. On the variation of anesthetic potency with vapor pressure. Anesthesiology. 1968 Sep-Oct; 29(5):1064-5.
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  748. Sachs D, Barker WF. Immediate postoperative management of the ileostomy. Surgery. 1966 Mar; 59(3):373-5.
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  749. SACHS D, BAILEY J, BAUMEISTER J, FURCOLOW ML. The association between antibodies against poliomyelitis and muscle weakness in a normal population. Pediatrics. 1958 May; 21(5):771-80.
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