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Inhibition of AKT with the orally active allosteric AKT inhibitor, MK-2206, sensitizes endometrial cancer cells to progestin.
Influence of AKT on progesterone action in endometrial diseases.
Akt regulates progesterone receptor B-dependent transcription and angiogenesis in endometrial cancer cells.
Progesterone receptor-B induction of BIRC3 protects endometrial cancer cells from AP1-59-mediated apoptosis.