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One or more keywords matched the following properties of Kokkinos, Vasileios
keywords Epilepsy
keywords Epilepsy surgery
overview Dr. Kokkinos received the diploma of Electrical & Computer Engineering and the MSc in Hardware-Software Integrated Systems from the Engineering School of the University of Patras, Greece, in 1998 and 2001. After working in the microelectronics industry, he shifted his interest towards the brain. In the graduate program of the Medical School of the University of Patras, Vasileios received the MSc in Basic Medical Sciences: Neurosciences in 2003, completing a thesis on the neurophysiology of the rat hippocampus. During the same period, he attended the undergraduate program of the Philosophy Department of the University of Patras, from which he graduated in 2005, with a thesis on neuroscience-derived theories of mind on visual perception. In the neurological sciences graduate program at McGill University, he then completed a thesis on the neurophysiology of human eye-head motor coordination, graduating in 2007. Under the supervision of George K. Kostopoulos, MD, PhD, Dr. Kokkinos then joined the neurophysiology unit of the Medical School of the University of Patras and completed a PhD thesis on the neurophysiology of normal human sleep in 2010. One year of his PhD training (2008-09) was devoted to intense and highly specialized training in epilepsy at the UCL Institute of Neurology, in London. He completed a training/research fellowship on fMRI and EEG-fMRI for presurgical evaluation of epilepsy, under the supervision of John S. Duncan, MD, PhD, and Louis Lemieux, PhD. During the same time, he was accepted in the graduate course on epileptology at King’s College in London, from which he graduated in 2009 with distinction, completing a thesis on invasive electrical cortical stimulation for patients undergoing epilepsy surgery under the supervision of Gonzalo Alarcon, MD, PhD, and Antonio Valentin, MD, PhD. He also attended the research team of the Department of Clinical Neurophysiology and Epilepsies at St. Thomas’ Hospital in London where he was trained in pediatric and adult epileptic EEG by Chrysostomos P. Panayiotopoulos, MD, PhD, and Michalis Koutroumanidis, MD, PhD. From 2009 to 2016, Dr. Kokkinos was head of neurophysiology and neuroimaging of the epilepsy program at St. Luke’s Hospital in Thessaloniki, Greece. His responsibilities in the pediatric and adult epilepsy program included the performance and supervision of procedures during both the non-invasive (video-EEG, MRI, fMRI, EEG-fMRI, DTI-tractography) and the invasive phases (acute and chronic ECoG, cortical electrical stimulation, neuronavigation) of the pre-surgical evaluation and surgical treatment protocol. From 2010 to 2017, Dr. Kokkinos also held a post-doctoral fellowship at the neurophysiology unit of the University of Patras Medical School under the mentorship of Dr. Kostopoulos, focusing on the neurophysiologic relations of sleep and epilepsy. He completed a second PhD thesis on neurophysiological features of focal and generalized epileptic syndromes of childhood in 2016. In 2017, he joined the faculty of the University of Pittsburgh Department of Neurological Surgery as a Research Instructor and lead neurophysiologist for epilepsy research. He supported the Comprehensive Epilepsy Program of University of Pittsburgh in surgical sEEG planning, intra-operative coordination and electrode implantation optimization, 3D reconstruction of sEEG implantation, iEEG interpretation and cortical electrical stimulation. Among other work, he discovered and published the first evidence for electrophysiological biomarkers of clinical response to RNS Therapy. He also established the intracranial EEG correlate of the 14&6/sec positive spikes EEG variant, and named it the hippocampal barque. Dr. Kokkinos is now Instructor of Neurosurgery at Massachusetts General Hospital and Harvard Medical School, focused in clinical epilepsy research and providing extensive clinical services to the Epilepsy Surgery Program.
One or more keywords matched the following items that are connected to Kokkinos, Vasileios
Item TypeName
Concept Epilepsy, Frontal Lobe
Concept Epilepsy, Temporal Lobe
Concept Epilepsy, Complex Partial
Concept Epilepsies, Partial
Concept Epilepsy, Absence
Concept Myoclonic Epilepsy, Juvenile
Concept Epilepsy, Generalized
Academic Article Closed-Loop Brain Stimulation for Drug-Resistant Epilepsy: Towards an Evidence-Based Approach to Personalized Medicine.
Academic Article Association of Closed-Loop Brain Stimulation Neurophysiological Features With Seizure Control Among Patients With Focal Epilepsy.
Academic Article Role of single pulse electrical stimulation (SPES) to guide electrode implantation under general anaesthesia in presurgical assessment of epilepsy.
Academic Article Thin isotropic FLAIR MR images at 1.5T increase the yield of focal cortical dysplasia transmantle sign detection in frontal lobe epilepsy.
Academic Article Spatiotemporal propagation patterns of generalized ictal spikes in childhood absence epilepsy.
Academic Article Generalized spike-wave discharges and seizures with focal ictal transformation: mechanisms in absence (CAE) and myoclonic (JME) IGEs.
Academic Article Focal and generalized EEG paroxysms in childhood absence epilepsy: topographic associations and distinctive behaviors during the first cycle of non-REM sleep.
Academic Article Temporal lobe "plus" epilepsy associated with oligodendroglial hyperplasia (MOGHE).
Academic Article The intracranial correlate of the 14&6/sec positive spikes normal scalp EEG variant.
Academic Article Extratemporal surface EEG features do not preclude successful surgical outcomes in drug-resistant epilepsy patients with unitemporal MRI lesions.
Academic Article Responsive Neurostimulation of the Thalamus Improves Seizure Control in Idiopathic Generalized Epilepsy: A Case Report.
Academic Article Spatiotemporal profiles of focal and generalised spikes in childhood absence epilepsy.
Academic Article Surgical outcome in neocortical resections of type IIId focal cortical dysplasia with accompanying medial temporal pathology.
Academic Article Hemispherotomy or lobectomy? The role of presurgical neuroimaging in a young case of a large porencephalic cyst with intractable epilepsy.
Academic Article Limited resection of focal cortical dysplasia and associated epileptogenic cortex may lead to positive surgical outcome.
Academic Article EEG-fMRI findings in late seizure recurrence following temporal lobectomy: A possible contribution of area tempestas.
Academic Article A Rational Approach to Understanding and Evaluating Responsive Neurostimulation.
Academic Article Epileptogenic networks in two patients with hypothalamic hamartoma.
Academic Article Implementation and evaluation of simultaneous video-electroencephalography and functional magnetic resonance imaging.
Academic Article Multifocal spatiotemporal distribution of interictal spikes in Panayiotopoulos syndrome.
Academic Article Histopathological Findings in Brain Tissue Obtained during Epilepsy Surgery.
Academic Article Sleep spindle alterations following-up a childhood absence epilepsy case
Academic Article Interpretation of the Intracranial Stereoelectroencephalography Signal.
Academic Article Neuromodulation of Epilepsy Networks.
Academic Article Ictal Onset Signatures Predict Favorable Outcomes of Laser Thermal Ablation for Mesial Temporal Lobe Epilepsy.
Academic Article Quantifying a frequency modulation response biomarker in responsive neurostimulation.
Academic Article Feasibility, Contrast Sensitivity and Network Specificity of Language fMRI in Presurgical Evaluation for Epilepsy and Brain Tumor Surgery.
Search Criteria
  • epilepsy
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.