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One or more keywords matched the following items that are connected to Richardson, Charles
Item TypeName
Academic Article Structural and functional organization of the DNA polymerase of bacteriophage T7.
Academic Article A single-stranded DNA-binding protein of bacteriophage T7 defective in DNA annealing.
Academic Article Genetic analysis of the interaction between bacteriophage T7 DNA polymerase and Escherichia coli thioredoxin.
Academic Article The acidic carboxyl terminus of the bacteriophage T7 gene 4 helicase/primase interacts with T7 DNA polymerase.
Academic Article DNA sequence analysis with a modified bacteriophage T7 DNA polymerase. Effect of pyrophosphorolysis and metal ions.
Academic Article A covalent linkage between the gene 5 DNA polymerase of bacteriophage T7 and Escherichia coli thioredoxin, the processivity factor: fate of thioredoxin during DNA synthesis.
Academic Article A unique loop in T7 DNA polymerase mediates the binding of helicase-primase, DNA binding protein, and processivity factor.
Academic Article Role of the acidic carboxyl-terminal domain of the single-stranded DNA-binding protein of bacteriophage T7 in specific protein-protein interactions.
Academic Article Interactions of gene 2.5 protein and DNA polymerase of bacteriophage T7.
Academic Article Formation of a DNA loop at the replication fork generated by bacteriophage T7 replication proteins.
Academic Article Role of the C-terminal residue of the DNA polymerase of bacteriophage T7.
Academic Article Gene 4 DNA primase of bacteriophage T7 mediates the annealing and extension of ribo-oligonucleotides at primase recognition sites.
Academic Article Rescue of bacteriophage T7 DNA polymerase of low processivity by suppressor mutations affecting gene 3 endonuclease.
Academic Article C-terminal phenylalanine of bacteriophage T7 single-stranded DNA-binding protein is essential for strand displacement synthesis by T7 DNA polymerase at a nick in DNA.
Academic Article Gene 4 protein of bacteriophage T7. Purification physical properties, and stimulation of T7 DNA polymerase during the elongation of polynucleotide chains.
Academic Article ENZYMIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. 18. THE REPAIR OF PARTIALLY SINGLE-STRANDED DNA TEMPLATES BY DNA POLYMERASE.
Academic Article Essential protein interactions within the replisome regulate DNA replication.
Academic Article Requirements for synthesis of ribonucleic acid primers during lagging strand synthesis by the DNA polymerase and gene 4 protein of bacteriophage T7.
Academic Article Interaction of mutant thioredoxins of Escherichia coli with the gene 5 protein of phage T7. The redox capacity of thioredoxin is not required for stimulation of DNA polymerase activity.
Academic Article Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis.
Academic Article The role of the zinc motif in sequence recognition by DNA primases.
Academic Article The C-terminal residues of bacteriophage T7 gene 4 helicase-primase coordinate helicase and DNA polymerase activities.
Academic Article The thioredoxin binding domain of bacteriophage T7 DNA polymerase confers processivity on Escherichia coli DNA polymerase I.
Academic Article Selective oxidation of the exonuclease domain of bacteriophage T7 DNA polymerase.
Academic Article Two modes of interaction of the single-stranded DNA-binding protein of bacteriophage T7 with the DNA polymerase-thioredoxin complex.
Academic Article A unique region in bacteriophage t7 DNA polymerase important for exonucleolytic hydrolysis of DNA.
Academic Article Dynamic DNA helicase-DNA polymerase interactions assure processive replication fork movement.
Academic Article Motors, switches, and contacts in the replisome.
Academic Article Mutations in the gene 5 DNA polymerase of bacteriophage T7 suppress the dominant lethal phenotype of gene 2.5 ssDNA binding protein lacking the C-terminal phenylalanine.
Academic Article Replication of duplex DNA by bacteriophage T7 DNA polymerase and gene 4 protein is accompanied by hydrolysis of nucleoside 5'-triphosphates.
Academic Article Studies on the replication of DNA by DNA polymerases
Academic Article Deoxyribonucleic acid polymerase of bacteriophage T7. Characterization of the exonuclease activities of the gene 5 protein and the reconstituted polymerase.
Academic Article DNA primase acts as a molecular brake in DNA replication.
Academic Article Characterization of the ribonucleic acid primers and the deoxyribonucleic acid product synthesized by the DNA polymerase and gene 4 protein of bacteriophage T7.
Academic Article Pyrovanadolysis, a pyrophosphorolysis-like reaction mediated by pyrovanadate, Mn2+, and DNA polymerase of bacteriophage T7.
Academic Article The carboxyl-terminal domain of bacteriophage T7 single-stranded DNA-binding protein modulates DNA binding and interaction with T7 DNA polymerase.
Academic Article Choreography of bacteriophage T7 DNA replication.
Academic Article Exchange of DNA polymerases at the replication fork of bacteriophage T7.
Academic Article Initiation of DNA replication at the primary origin of bacteriophage T7 by purified proteins. Initiation of bidirectional synthesis.
Academic Article Gene 4 protein of bacteriophage T7. Characterization of the product synthesized by the T7 DNA polymerase and gene 4 protein in the absence of ribonucleoside 5'-triphosphates.
Academic Article Thioredoxin suppresses microscopic hopping of T7 DNA polymerase on duplex DNA.
Academic Article Amino acid changes in a unique sequence of bacteriophage T7 DNA polymerase alter the processivity of nucleotide polymerization.
Academic Article A unique loop in the DNA-binding crevice of bacteriophage T7 DNA polymerase influences primer utilization.
Academic Article A Mutation in the gene-encoding bacteriophage T7 DNA polymerase that renders the phage temperature-sensitive.
Academic Article ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. XIV. FURTHER PURIFICATION AND PROPERTIES OF DEOXYRIBONUCLEIC ACID POLYMERASE OF ESCHERICHIA COLI.
Academic Article A single residue in DNA polymerases of the Escherichia coli DNA polymerase I family is critical for distinguishing between deoxy- and dideoxyribonucleotides.
Academic Article Lagging strand synthesis in coordinated DNA synthesis by bacteriophage t7 replication proteins.
Academic Article Characterization of strand displacement synthesis catalyzed by bacteriophage T7 DNA polymerase.
Academic Article A preformed, topologically stable replication fork. Characterization of leading strand DNA synthesis catalyzed by T7 DNA polymerase and T7 gene 4 protein.
Academic Article Coordination of leading and lagging strand DNA synthesis at the replication fork of bacteriophage T7.
Academic Article Peptide ligands specific to the oxidized form of Escherichia coli thioredoxin.
Academic Article Effect of manganese ions on the incorporation of dideoxynucleotides by bacteriophage T7 DNA polymerase and Escherichia coli DNA polymerase I.
Academic Article Promiscuous usage of nucleotides by the DNA helicase of bacteriophage T7: determinants of nucleotide specificity.
Academic Article The effect of the T7 and Escherichia coli DNA-binding proteins at the replication fork of bacteriophage T7.
Academic Article Mechanisms for the initiation of bacteriophage T7 DNA replication.
Academic Article Bypass of a nick by the replisome of bacteriophage T7.
Academic Article Deoxyribonucleic acid polymerase of bacteriophage T7. Purification and properties of the phage-encoded subunit, the gene 5 protein.
Academic Article An interaction between DNA polymerase and helicase is essential for the high processivity of the bacteriophage T7 replisome.
Academic Article The linker region between the helicase and primase domains of the bacteriophage T7 gene 4 protein is critical for hexamer formation.
Academic Article Direct observation of enzymes replicating DNA using a single-molecule DNA stretching assay.
Academic Article Selective inactivation of the exonuclease activity of bacteriophage T7 DNA polymerase by in vitro mutagenesis.
Academic Article Escherichia coli thioredoxin confers processivity on the DNA polymerase activity of the gene 5 protein of bacteriophage T7.
Academic Article Escherichia coli thioredoxin stabilizes complexes of bacteriophage T7 DNA polymerase and primed templates.
Academic Article Leading and lagging strand synthesis at the replication fork of bacteriophage T7. Distinct properties of T7 gene 4 protein as a helicase and primase.
Academic Article THE DEOXYRIBONUCLEASES OF ESCHERICHIA COLI. IV. AN EXONUCLEASE ACTIVITY PRESENT IN PURIFIED PREPARATIONS OF DEOXYRIBONUCLEIC ACID POLYMERASE.
Academic Article The highly processive DNA polymerase of bacteriophage T5. Role of the unique N and C termini.
Academic Article Priming of deoxyribonucleic acid synthesis on phage fd and phiX174 templates by oligoribonucleotides contaminating nucleoside 5'-triphosphates.
Academic Article Interactions of Escherichia coli thioredoxin, the processivity factor, with bacteriophage T7 DNA polymerase and helicase.
Academic Article Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis.
Academic Article Helicase-DNA polymerase interaction is critical to initiate leading-strand DNA synthesis.
Academic Article Two forms of the DNA polymerase of bacteriophage T7.
Academic Article Amino acid residues critical for the interaction between bacteriophage T7 DNA polymerase and Escherichia coli thioredoxin.
Academic Article Conformational dynamics of bacteriophage T7 DNA polymerase and its processivity factor, Escherichia coli thioredoxin.
Academic Article Simultaneous single-molecule measurements of phage T7 replisome composition and function reveal the mechanism of polymerase exchange.
Academic Article DNA sequence analysis with a modified bacteriophage T7 DNA polymerase.
Academic Article Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution.
Academic Article Acidic carboxyl-terminal domain of gene 2.5 protein of bacteriophage T7 is essential for protein-protein interactions.
Academic Article Modular architecture of the bacteriophage T7 primase couples RNA primer synthesis to DNA synthesis.
Academic Article Interactions of the DNA polymerase and gene 4 protein of bacteriophage T7. Protein-protein and protein-DNA interactions involved in RNA-primed DNA synthesis.
Academic Article Dissection of RNA-primed DNA synthesis catalyzed by gene 4 protein and DNA polymerase of bacteriophage T7. Coupling of RNA primer and DNA synthesis.
Academic Article A complex of the bacteriophage T7 primase-helicase and DNA polymerase directs primer utilization.
Academic Article Thioredoxin, the processivity factor, sequesters an exposed cysteine in the thumb domain of bacteriophage T7 DNA polymerase.
Academic Article Initiation of DNA replication at the primary origin of bacteriophage T7 by purified proteins. Site and direction of initial DNA synthesis.
Academic Article Bacteriophage T7 DNA replication. Synthesis of lagging strands in a reconstituted system using purified proteins.
Concept DNA-Directed DNA Polymerase
Academic Article Single-molecule studies of polymerase dynamics and stoichiometry at the bacteriophage T7 replication machinery.
Academic Article Genetic requirements for sensitivity of bacteriophage t7 to dideoxythymidine.
Academic Article It seems like only yesterday.
Academic Article Binding Affinities among DNA Helicase-Primase, DNA Polymerase, and Replication Intermediates in the Replisome of Bacteriophage T7.
Academic Article Primer release is the rate-limiting event in lagging-strand synthesis mediated by the T7 replisome.
Academic Article The Replication System of Bacteriophage T7.
Academic Article Deep-sea vent phage DNA polymerase specifically initiates DNA synthesis in the absence of primers.
Academic Article Kinetics of Lagging-strand DNA Synthesis In Vitro by the Bacteriophage T7 Replication Proteins.
Academic Article Hydrophobic Residue in Escherichia coli Thioredoxin Critical for the Processivity of T7 DNA Polymerase.
Academic Article Catalytically inactive T7 DNA polymerase imposes a lethal replication roadblock.
Search Criteria
  • DNA Directed DNA Polymerase
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.