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One or more keywords matched the following items that are connected to Sankaran, Vijay
Item TypeName
Academic Article DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease.
Academic Article Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation.
Academic Article A functional element necessary for fetal hemoglobin silencing.
Academic Article Reversing the hemoglobin switch.
Academic Article Hemoglobin disorders in the developing world: a perspective from Sri Lanka.
Academic Article Modifier genes in Mendelian disorders: the example of hemoglobin disorders.
Academic Article The switch from fetal to adult hemoglobin.
Academic Article Targeted therapeutic strategies for fetal hemoglobin induction.
Academic Article Clinical experience with fetal hemoglobin induction therapy in patients with ß-thalassemia.
Academic Article Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia.
Academic Article Advances in the understanding of haemoglobin switching.
Academic Article Persistence of fetal hemoglobin expression in an older child with trisomy 13.
Academic Article Fetal hemoglobin levels and morbidity in untransfused patients with ß-thalassemia intermedia.
Academic Article Transcriptional silencing of fetal hemoglobin by BCL11A.
Academic Article MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13.
Academic Article Heterozygous disruption of human SOX6 is insufficient to impair erythropoiesis or silencing of fetal hemoglobin.
Academic Article Therapeutic levels of fetal hemoglobin in erythroid progeny of ß-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer.
Academic Article Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing.
Academic Article Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.
Concept Fetal Hemoglobin
Concept Hemoglobin, Sickle
Concept Hemoglobin A
Academic Article Rare complete loss of function provides insight into a pleiotropic genome-wide association study locus.
Academic Article Anemia: progress in molecular mechanisms and therapies.
Academic Article BCL11A deletions result in fetal hemoglobin persistence and neurodevelopmental alterations.
Academic Article Characterization of Deletions of the HBA and HBB Loci by Array Comparative Genomic Hybridization.
Academic Article Society for Pediatric Research 2015 Young Investigator Award: genetics of human hematopoiesis-what patients can teach us about blood cell production.
Academic Article Regulation of the fetal hemoglobin silencing factor BCL11A.
Grant Identifying Genome-wide Association Study-Nominated Regulators of Erythropoiesis
Grant Identifying Genome-wide Association Study-Nominated Regulators of Erythropoiesis
Grant Translational and clinical studies targeting y-globin modulation
Academic Article Normal hematologic parameters and fetal hemoglobin silencing with heterozygous IKZF1 mutations.
Academic Article Common a-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease.
Academic Article A chance to cut (the genome) is a chance to cure.
Academic Article Heritability of fetal hemoglobin, white cell count, and other clinical traits from a sickle cell disease family cohort.
Academic Article A chance encounter changes everything.
Academic Article Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation.
Grant Integrating Human Genetics and Single-Cell Functional Assays to Elucidate Mechanisms of Fetal Hemoglobin Regulation
Academic Article A unified model of human hemoglobin switching through single-cell genome editing.
Academic Article Pathogenic BCL11A variants provide insights into the mechanisms of human fetal hemoglobin silencing.
Search Criteria
  • Hemoglobin C
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.