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One or more keywords matched the following items that are connected to Tenen, Daniel
Item TypeName
Academic Article PU. 1 is not essential for early myeloid gene expression but is required for terminal myeloid differentiation.
Academic Article Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice.
Academic Article Cellular myosin heavy chain in human leukocytes: isolation of 5' cDNA clones, characterization of the protein, chromosomal localization, and upregulation during myeloid differentiation.
Academic Article Transcription factors, normal myeloid development, and leukemia.
Academic Article Upregulation of interleukin 6 and granulocyte colony-stimulating factor receptors by transcription factor CCAAT enhancer binding protein alpha (C/EBP alpha) is critical for granulopoiesis.
Academic Article Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells.
Academic Article Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha.
Academic Article Downregulation of c-Jun expression by transcription factor C/EBPalpha is critical for granulocytic lineage commitment.
Academic Article Granulocyte inducer C/EBPalpha inactivates the myeloid master regulator PU.1: possible role in lineage commitment decisions.
Academic Article Use of a promoterless Renilla luciferase vector as an internal control plasmid for transient co-transfection assays of Ras-mediated transcription activation.
Academic Article Multiple functional domains of AML1: PU.1 and C/EBPalpha synergize with different regions of AML1.
Academic Article Ras signaling enhances the activity of C/EBP alpha to induce granulocytic differentiation by phosphorylation of serine 248.
Academic Article C/EBPbeta is required for 'emergency' granulopoiesis.
Academic Article Characterization of the myeloid-specific CD11b promoter.
Academic Article The amino terminal and E2F interaction domains are critical for C/EBP alpha-mediated induction of granulopoietic development of hematopoietic cells.
Academic Article CCAAT/enhancer binding proteins alpha and epsilon cooperate with all-trans retinoic acid in therapy but differ in their antileukemic activities.
Academic Article Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation.
Academic Article PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element.
Academic Article Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia.
Academic Article PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2.
Academic Article Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha.
Academic Article pDP4, a novel glycoprotein secreted by mature granulocytes, is regulated by transcription factor PU.1.
Academic Article CCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing.
Academic Article Phosphorylation of C/EBPalpha inhibits granulopoiesis.
Academic Article CDDO induces granulocytic differentiation of myeloid leukemic blasts through translational up-regulation of p42 CCAAT enhancer binding protein alpha.
Academic Article PML-RARalpha initiates leukemia by conferring properties of self-renewal to committed promyelocytic progenitors.
Academic Article Differential expression of CD11b/CD18 (Mo1) and myeloperoxidase genes during myeloid differentiation.
Academic Article Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis.
Academic Article C/EBP? deregulation results in differentiation arrest in acute myeloid leukemia.
Academic Article Cyclic AMP responsive element binding proteins are involved in 'emergency' granulopoiesis through the upregulation of CCAAT/enhancer binding protein ß.
Academic Article c-Myc is a critical target for c/EBPalpha in granulopoiesis.
Academic Article Induction of granulocytic differentiation by 2 pathways.
Academic Article c-Jun is a JNK-independent coactivator of the PU.1 transcription factor.
Academic Article Reciprocal roles for CCAAT/enhancer binding protein (C/EBP) and PU.1 transcription factors in Langerhans cell commitment.
Academic Article The fusion protein AML1-ETO in acute myeloid leukemia with translocation t(8;21) induces c-jun protein expression via the proximal AP-1 site of the c-jun promoter in an indirect, JNK-dependent manner.
Academic Article Characterization of a distinct binding site for the prokaryotic chaperone, GroEL, on a human granulocyte ribonuclease.
Academic Article Function of PU.1 (Spi-1), C/EBP, and AML1 in early myelopoiesis: regulation of multiple myeloid CSF receptor promoters.
Academic Article Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells.
Academic Article Inhibition of hematopoiesis by competitive binding of transcription factor PU.1.
Academic Article PU.1 (Spi-1) and C/EBP alpha regulate expression of the granulocyte-macrophage colony-stimulating factor receptor alpha gene.
Academic Article Block of C/EBP alpha function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations.
Academic Article The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages.
Academic Article Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AML.
Academic Article Optimization of transient transfection into human myeloid cell lines using a luciferase reporter gene.
Academic Article Heterozygous PU.1 mutations are associated with acute myeloid leukemia.
Academic Article Neutrophils and monocytes express high levels of PU.1 (Spi-1) but not Spi-B.
Academic Article PU.1 (Spi-1) and C/EBP alpha regulate the granulocyte colony-stimulating factor receptor promoter in myeloid cells.
Academic Article Biolistic expression of the macrophage colony stimulating factor receptor in organotypic cultures induces an inflammatory response.
Academic Article Target proteins of C/EBPalphap30 in AML: C/EBPalphap30 enhances sumoylation of C/EBPalphap42 via up-regulation of Ubc9.
Academic Article Targeting CDK1 promotes FLT3-activated acute myeloid leukemia differentiation through C/EBPa.
Academic Article Monocyte chemoattractant protein-1 gene is expressed in activated neutrophils and retinoic acid-induced human myeloid cell lines.
Academic Article Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia.
Academic Article Rearrangement of the AML1/CBFA2 gene in myeloid leukemia with the 3;21 translocation: expression of co-existing multiple chimeric genes with similar functions as transcriptional repressors, but with opposite tumorigenic properties.
Academic Article C/EBPa regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations.
Academic Article CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter.
Academic Article The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor.
Academic Article Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1).
Academic Article The chimeric genes AML1/MDS1 and AML1/EAP inhibit AML1B activation at the CSF1R promoter, but only AML1/MDS1 has tumor-promoter properties.
Academic Article Pegylated granulocyte colony-stimulating factor mobilizes CD34+ cells with different stem and progenitor subsets and distinct functional properties in comparison with unconjugated granulocyte colony-stimulating factor.
Academic Article Molecular cloning of the human eosinophil-derived neurotoxin: a member of the ribonuclease gene family.
Academic Article CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors.
Concept Receptors, Granulocyte Colony-Stimulating Factor
Concept Macrophage Colony-Stimulating Factor
Concept Receptors, Granulocyte-Macrophage Colony-Stimulating Factor
Concept Granulocyte Precursor Cells
Concept Receptor, Macrophage Colony-Stimulating Factor
Concept Granulocyte Colony-Stimulating Factor
Concept Receptors, Colony-Stimulating Factor
Concept Granulocyte-Macrophage Colony-Stimulating Factor
Concept Granulocytes
Concept Colony-Stimulating Factors
Academic Article Transcription factor C/EBPa-induced microRNA-30c inactivates Notch1 during granulopoiesis and is downregulated in acute myeloid leukemia.
Academic Article Essential role of PU.1 in maintenance of mixed lineage leukemia-associated leukemic stem cells.
Academic Article Hematopoietic Differentiation Is Required for Initiation of Acute Myeloid Leukemia.
Academic Article Acetylation of C/EBPa inhibits its granulopoietic function.
Academic Article EVI2B is a C/EBPa target gene required for granulocytic differentiation and functionality of hematopoietic progenitors.
Academic Article Disruption of the C/EBPa-miR-182 balance impairs granulocytic differentiation.
Academic Article C/EBPß is required for survival of Ly6C- monocytes.
Academic Article C/EBP? is dispensable for steady-state and emergency granulopoiesis.
Academic Article Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBPa.
Academic Article ß-Catenin-TCF/LEF signaling promotes steady-state and emergency granulopoiesis via G-CSF receptor upregulation.
Search Criteria
  • Granulocyte
  • Colony Stimulating Factor
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.