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One or more keywords matched the following items that are connected to Tenen, Daniel
Item TypeName
Academic Article Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice.
Academic Article A dominant-negative mutant of C/EBPalpha, associated with acute myeloid leukemias, inhibits differentiation of myeloid and erythroid progenitors of man but not mouse.
Academic Article Upregulation of interleukin 6 and granulocyte colony-stimulating factor receptors by transcription factor CCAAT enhancer binding protein alpha (C/EBP alpha) is critical for granulopoiesis.
Academic Article AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.
Academic Article Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha.
Academic Article Abnormalities of the CEBP alpha transcription factor: a major target in acute myeloid leukemia.
Academic Article Downregulation of c-Jun expression by transcription factor C/EBPalpha is critical for granulocytic lineage commitment.
Academic Article The hematopoietic transcription factor AML1 (RUNX1) is negatively regulated by the cell cycle protein cyclin D3.
Academic Article Immunohistochemical analysis of C/EBPalpha in non-small cell lung cancer reveals frequent down-regulation in stage II and IIIA tumors: a correlative study of E3590.
Academic Article Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1.
Academic Article Granulocyte inducer C/EBPalpha inactivates the myeloid master regulator PU.1: possible role in lineage commitment decisions.
Academic Article C/EBPalpha is required for proteolytic cleavage of cyclin A by calpain 3 in myeloid precursor cells.
Academic Article Biallelic mutations in the CEBPA gene and low CEBPA expression levels as prognostic markers in intermediate-risk AML.
Academic Article Multiple functional domains of AML1: PU.1 and C/EBPalpha synergize with different regions of AML1.
Academic Article Ras signaling enhances the activity of C/EBP alpha to induce granulocytic differentiation by phosphorylation of serine 248.
Academic Article Dysregulation of the C/EBPalpha differentiation pathway in human cancer.
Academic Article Respiratory failure due to differentiation arrest and expansion of alveolar cells following lung-specific loss of the transcription factor C/EBPalpha in mice.
Academic Article C/EBPbeta is required for 'emergency' granulopoiesis.
Academic Article The amino terminal and E2F interaction domains are critical for C/EBP alpha-mediated induction of granulopoietic development of hematopoietic cells.
Academic Article CCAAT/enhancer binding proteins alpha and epsilon cooperate with all-trans retinoic acid in therapy but differ in their antileukemic activities.
Academic Article Down-regulation and antiproliferative role of C/EBPalpha in lung cancer.
Academic Article CCAAT/Enhancer binding proteins repress the leukemic phenotype of acute myeloid leukemia.
Academic Article Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia.
Academic Article Overexpression of TRIB2 in human lung cancers contributes to tumorigenesis through downregulation of C/EBPa.
Academic Article Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha.
Academic Article Down regulation of PSA by C/EBPalpha is associated with loss of AR expression and inhibition of PSA promoter activity in the LNCaP cell line.
Academic Article A transcriptional profiling study of CCAAT/enhancer binding protein targets identifies hepatocyte nuclear factor 3 beta as a novel tumor suppressor in lung cancer.
Academic Article CCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing.
Academic Article Phosphorylation of C/EBPalpha inhibits granulopoiesis.
Academic Article CDDO induces granulocytic differentiation of myeloid leukemic blasts through translational up-regulation of p42 CCAAT enhancer binding protein alpha.
Academic Article C/EBP? deregulation results in differentiation arrest in acute myeloid leukemia.
Academic Article Cyclic AMP responsive element binding proteins are involved in 'emergency' granulopoiesis through the upregulation of CCAAT/enhancer binding protein ß.
Academic Article c-Myc is a critical target for c/EBPalpha in granulopoiesis.
Academic Article Induction of granulocytic differentiation by 2 pathways.
Academic Article Proteomic analysis of transcription factor interactions in myeloid stem cell development and leukaemia.
Academic Article Metabolic response of mice to a postnatal ablation of CCAAT/enhancer-binding protein alpha.
Academic Article C/EBPa controls acquisition and maintenance of adult haematopoietic stem cell quiescence.
Academic Article Reciprocal roles for CCAAT/enhancer binding protein (C/EBP) and PU.1 transcription factors in Langerhans cell commitment.
Academic Article Function of PU.1 (Spi-1), C/EBP, and AML1 in early myelopoiesis: regulation of multiple myeloid CSF receptor promoters.
Academic Article Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells.
Academic Article Absence of the transcription factor CCAAT enhancer binding protein alpha results in loss of myeloid identity in bcr/abl-induced malignancy.
Academic Article Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia.
Academic Article PU.1 (Spi-1) and C/EBP alpha regulate expression of the granulocyte-macrophage colony-stimulating factor receptor alpha gene.
Academic Article Block of C/EBP alpha function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations.
Academic Article The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages.
Academic Article c-Jun homodimers can function as a context-specific coactivator.
Academic Article C/EBPalpha binds and activates the PU.1 distal enhancer to induce monocyte lineage commitment.
Academic Article Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AML.
Academic Article PU.1 (Spi-1) and C/EBP alpha regulate the granulocyte colony-stimulating factor receptor promoter in myeloid cells.
Academic Article C/EBPa and DEK coordinately regulate myeloid differentiation.
Academic Article C/EBP alpha mutations in lung cancer.
Academic Article Dominant-interfering C/EBPalpha stimulates primitive erythropoiesis in zebrafish.
Academic Article Target proteins of C/EBPalphap30 in AML: C/EBPalphap30 enhances sumoylation of C/EBPalphap42 via up-regulation of Ubc9.
Academic Article Phosphorylation of CCAAT/enhancer-binding protein alpha regulates GLUT4 expression and glucose transport in adipocytes.
Academic Article Targeting CDK1 promotes FLT3-activated acute myeloid leukemia differentiation through C/EBPa.
Academic Article Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia.
Academic Article Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis.
Academic Article Mutations of the myeloid transcription factor CEBPA are not associated with the blast crisis of chronic myeloid leukaemia.
Academic Article Proteomic discovery of Max as a novel interacting partner of C/EBPalpha: a Myc/Max/Mad link.
Academic Article C/EBPa regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations.
Academic Article C/EBPß promotes BCR-ABL-mediated myeloid expansion and leukemic stem cell exhaustion.
Academic Article CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter.
Academic Article Elevated c-Jun expression in acute myeloid leukemias inhibits C/EBPalpha DNA binding via leucine zipper domain interaction.
Academic Article C/EBPbeta: a major PML-RARA-responsive gene in retinoic acid-induced differentiation of APL cells.
Academic Article CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors.
Concept CCAAT-Enhancer-Binding Proteins
Concept CCAAT-Enhancer-Binding Protein-alpha
Concept CCAAT-Enhancer-Binding Protein-beta
Concept CCAAT-Enhancer-Binding Protein-delta
Academic Article C/EBPa is required for development of dendritic cell progenitors.
Academic Article Transcription factor C/EBPa-induced microRNA-30c inactivates Notch1 during granulopoiesis and is downregulated in acute myeloid leukemia.
Academic Article Sox4 is a key oncogenic target in C/EBPa mutant acute myeloid leukemia.
Academic Article DNMT1-interacting RNAs block gene-specific DNA methylation.
Academic Article The gene signature in CCAAT-enhancer-binding protein a dysfunctional acute myeloid leukemia predicts responsiveness to histone deacetylase inhibitors.
Academic Article Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal.
Academic Article A Cell-Based High-Throughput Screening for Inducers of Myeloid Differentiation.
Academic Article Acetylation of C/EBPa inhibits its granulopoietic function.
Academic Article Targeted BMI1 inhibition impairs tumor growth in lung adenocarcinomas with low CEBPa expression.
Grant ROLE OF C/EBPalpha AND MYELOPOIESIS
Grant TRANSCRIPTION FACTOR MUTATIONS AND HUMAN AML
Academic Article EVI2B is a C/EBPa target gene required for granulocytic differentiation and functionality of hematopoietic progenitors.
Academic Article Neutrophil Elastase Regulates Emergency Myelopoiesis Preceding Systemic Inflammation in Diet-induced Obesity.
Academic Article Disruption of the C/EBPa-miR-182 balance impairs granulocytic differentiation.
Academic Article C/EBPa deregulation as a paradigm for leukemogenesis.
Academic Article C/EBPß is required for survival of Ly6C- monocytes.
Academic Article ZNF143 protein is an important regulator of the myeloid transcription factor C/EBPa.
Academic Article LSD1 inhibition exerts its antileukemic effect by recommissioning PU.1- and C/EBPa-dependent enhancers in AML.
Academic Article C/EBP? is dispensable for steady-state and emergency granulopoiesis.
Academic Article Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBPa.
Academic Article C/EBPß is a critical mediator of IFN-a-induced exhaustion of chronic myeloid leukemia stem cells.
Search Criteria
  • CCAAT Enhancer Binding Proteins
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.