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One or more keywords matched the following properties of Laidlaw, Tanya
overview Our research is focused on understanding Aspirin Exacerbated Respiratory Disease (AERD), also known as Aspirin Sensitive Asthma or Samter’s Triad. We are investigating the causative mechanisms of AERD/Samter’s Triad, as well as exploring new treatments for the disease and working to understand how patients can become desensitized to aspirin. Our group at the Brigham and Women’s Hospital’s AERD Center follows over 900 patients with AERD/Samter’s Triad and have several ongoing research studies that are currently recruiting and enrolling patients. We are also actively involved in research to further knowledge about the causes of chronic rhinosinusitis and nasal polyps, and to better understand the consequences of being allergic to aspirin or NSAIDs.
One or more keywords matched the following items that are connected to Laidlaw, Tanya
Item TypeName
Academic Article Cysteinyl leukotriene overproduction in aspirin-exacerbated respiratory disease is driven by platelet-adherent leukocytes.
Concept Nasal Polyps
Academic Article Impaired E Prostanoid2 Expression and Resistance to Prostaglandin E2 in Nasal Polyp Fibroblasts from Subjects with Aspirin-Exacerbated Respiratory Disease.
Academic Article How Patient Experiences Should Change Our Approach to Treating Patients with Aspirin-Exacerbated Respiratory Disease.
Academic Article Aspirin-Exacerbated Respiratory Disease--New Prime Suspects.
Academic Article Thymic stromal lymphopoietin controls prostaglandin D2 generation in patients with aspirin-exacerbated respiratory disease.
Academic Article PLA2G5 regulates transglutaminase activity of human IL-4-activated M2 macrophages through PGE2 generation.
Academic Article Aspirin-exacerbated respiratory disease: not always "adult-onset".
Academic Article Automated identification of an aspirin-exacerbated respiratory disease cohort.
Academic Article Allergic inflammatory memory in human respiratory epithelial progenitor cells.
Academic Article A retrospective analysis of esophageal eosinophilia in patients with aspirin-exacerbated respiratory disease.
Academic Article Dexpramipexole depletes blood and tissue eosinophils in nasal polyps with no change in polyp size.
Academic Article A 1-Day, 90-Minute Aspirin Challenge and Desensitization Protocol in Aspirin-Exacerbated Respiratory Disease.
Academic Article Sinus surgery improves lower respiratory tract reactivity during aspirin desensitization for AERD.
Academic Article Dupilumab improves nasal polyp burden and asthma control in patients with CRSwNP and AERD.
Academic Article Longitudinal progression of aspirin-exacerbated respiratory disease: analysis of a national insurance claims database.
Academic Article Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials.
Academic Article Biologics in chronic rhinosinusitis with nasal polyposis.
Academic Article Clinical Research Needs for the Management of Chronic Rhinosinusitis with Nasal Polyps in the New Era of Biologics: A National Institute of Allergy and Infectious Diseases Workshop.
Academic Article IL-5Ra marks nasal polyp IgG4- and IgE-expressing cells in aspirin-exacerbated respiratory disease.
Academic Article Guidance for contemporary use of biologics in management of chronic rhinosinusitis with nasal polyps: discussion from a National Institutes of Health-sponsored workshop.
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  • Nasal Polyps
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.