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One or more keywords matched the following items that are connected to Kuchroo, Vijay
Item TypeName
Academic Article Autopathogenic T helper cell type 1 (Th1) and protective Th2 clones differ in their recognition of the autoantigenic peptide of myelin proteolipid protein.
Academic Article IL-4, IL-10, IL-13, and TGF-beta from an altered peptide ligand-specific Th2 cell clone down-regulate adoptive transfer of experimental autoimmune encephalomyelitis.
Academic Article Cutting edge: CD4+CD25+ regulatory T cells contribute to gender differences in susceptibility to experimental autoimmune encephalomyelitis.
Academic Article IL-10 plays an important role in the homeostatic regulation of the autoreactive repertoire in naive mice.
Academic Article Modified amino acid copolymers suppress myelin basic protein 85-99-induced encephalomyelitis in humanized mice through different effects on T cells.
Academic Article Amelioration of proteolipid protein 139-151-induced encephalomyelitis in SJL mice by modified amino acid copolymers and their mechanisms.
Academic Article Genetic susceptibility or resistance to autoimmune encephalomyelitis in MHC congenic mice is associated with differential production of pro- and anti-inflammatory cytokines.
Academic Article Fulminant spontaneous autoimmunity of the central nervous system in mice transgenic for the myelin proteolipid protein-specific T cell receptor.
Academic Article Changes in the strength of co-stimulation through the B7/CD28 pathway alter functional T cell responses to altered peptide ligands.
Academic Article Genetics of experimental autoimmune encephalomyelitis.
Academic Article Cutting edge: CD94/NKG2 is expressed on Th1 but not Th2 cells and costimulates Th1 effector functions.
Academic Article The ICOS molecule plays a crucial role in the development of mucosal tolerance.
Academic Article IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10- and IL-4-deficient and transgenic mice.
Academic Article Immunological basis for the development of tissue inflammation and organ-specific autoimmunity in animal models of multiple sclerosis.
Academic Article T cell tolerance induced by cross-reactive TCR ligands can be broken by superagonist resulting in anti-inflammatory T cell cytokine production.
Academic Article The diabetes susceptibility locus Idd5.1 on mouse chromosome 1 regulates ICOS expression and modulates murine experimental autoimmune encephalomyelitis.
Academic Article Role of Th1 and Th17 cells in organ-specific autoimmunity.
Academic Article Antigen-driven regulation of experimental autoimmune encephalomyelitis.
Academic Article Expression and characterization of TCA3: a murine inflammatory protein.
Academic Article Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway.
Academic Article Galectin-1 triggers an immunoregulatory signature in Th cells functionally defined by IL-10 expression.
Academic Article Immunology. The yin and yang of follicular helper T cells.
Academic Article Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells.
Academic Article Interplay between effector Th17 and regulatory T cells.
Academic Article Cytosolic phospholipase A2a blockade abrogates disease during the tissue-damage effector phase of experimental autoimmune encephalomyelitis by its action on APCs.
Academic Article Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis.
Academic Article Dissimilar background genes control susceptibility to autoimmune disease in the context of different MHC haplotypes: NOD.H-2(s) congenic mice are relatively resistant to both experimental autoimmune encephalomyelitis and type I diabetes.
Academic Article Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis.
Academic Article Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells.
Academic Article Discordant effects of anti-VLA-4 treatment before and after onset of relapsing experimental autoimmune encephalomyelitis.
Academic Article The TIGIT/CD226 axis regulates human T cell function.
Academic Article TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines.
Academic Article Th17 cells: effector T cells with inflammatory properties.
Academic Article IL-12 family cytokines: immunological playmakers.
Academic Article T Cell Ig- and mucin-domain-containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis.
Academic Article The TIM gene family regulates autoimmune and allergic diseases.
Academic Article Th3 cells in peripheral tolerance. I. Induction of Foxp3-positive regulatory T cells by Th3 cells derived from TGF-beta T cell-transgenic mice.
Academic Article Induction and effector functions of T(H)17 cells.
Academic Article Cutting edge: IL-23 receptor deficiency prevents the development of lupus nephritis in C57BL/6-lpr/lpr mice.
Academic Article Th17 cells: from precursors to players in inflammation and infection.
Academic Article Tim-2 regulates T helper type 2 responses and autoimmunity.
Academic Article Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells.
Academic Article Heteroclitic proliferative responses and changes in cytokine profile induced by altered peptides: implications for autoimmunity.
Academic Article The role of SAP in murine CD150 (SLAM)-mediated T-cell proliferation and interferon gamma production.
Academic Article Functional Th1 cells are required for surgical adhesion formation in a murine model.
Academic Article T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding ROR?t.
Concept Cytokines
Academic Article Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis.
Academic Article The CD226/CD155 interaction regulates the proinflammatory (Th1/Th17)/anti-inflammatory (Th2) balance in humans.
Academic Article IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39.
Academic Article The dichotomous pattern of IL-12r and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation.
Academic Article Small-molecule ROR?t antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms.
Academic Article Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses.
Academic Article Specific targeting of the IL-23 receptor, using a novel small peptide noncompetitive antagonist, decreases the inflammatory response.
Academic Article Cutting edge: maresin-1 engages regulatory T cells to limit type 2 innate lymphoid cell activation and promote resolution of lung inflammation.
Academic Article KIM-1-mediated phagocytosis reduces acute injury to the kidney.
Academic Article Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation.
Academic Article Sodium chloride inhibits the suppressive function of FOXP3+ regulatory T cells.
Grant ORAL TOLERANCE IN MURINE AND HUMAN AUTOIMMUNE DISEASES
Academic Article T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation.
Academic Article Multilayer regulation of CD4 T cell subset differentiation in the era of single cell genomics.
Search Criteria
  • Cytokines
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.