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Escherichia coli Shiga toxins induce apoptosis in epithelial cells that is regulated by the Bcl-2 family.
BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition.
Proto-Oncogene Proteins c-bcl-2
Improving apoptotic responses to targeted therapy.
Clinical profiling of BCL-2 family members in the setting of BRAF inhibition offers a rationale for targeting de novo resistance using BH3 mimetics.
Destabilization of NOXA mRNA as a common resistance mechanism to targeted therapies.
Proto Oncogene Proteins c bcl 6