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One or more keywords matched the following items that are connected to Seidman, Jonathan
Item TypeName
Academic Article Altered regulatory function of two familial hypertrophic cardiomyopathy troponin T mutants.
Academic Article Functional role of AMP-activated protein kinase in the heart during exercise.
Academic Article Targeted ablation of the murine alpha-tropomyosin gene.
Academic Article Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function.
Academic Article Accelerated cardiomyopathy in mice with overexpression of cardiac G(s)alpha and a missense mutation in the alpha-myosin heavy chain.
Academic Article Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy.
Academic Article The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy.
Academic Article Mutations in cardiac myosin heavy chain genes cause familial hypertrophic cardiomyopathy.
Academic Article Ventricular arrhythmia vulnerability in cardiomyopathic mice with homozygous mutant Myosin-binding protein C gene.
Academic Article Expression and functional assessment of a truncated cardiac troponin T that causes hypertrophic cardiomyopathy. Evidence for a dominant negative action.
Academic Article Clinical features of hypertrophic cardiomyopathy caused by mutation of a "hot spot" in the alpha-tropomyosin gene.
Academic Article cis-dominance of rat atrial natriuretic factor gene regulatory sequences in transgenic mice.
Academic Article Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy.
Academic Article Altered crossbridge kinetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy.
Academic Article Biosynthesis and secretion of proatrial natriuretic factor by cultured rat cardiocytes.
Academic Article Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice.
Academic Article Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban.
Academic Article Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression.
Academic Article Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff-Parkinson-White syndrome in glycogen storage cardiomyopathy.
Academic Article Effect of cardiac myosin binding protein-C on mechanoenergetics in mouse myocardium.
Academic Article N488I mutation of the gamma2-subunit results in bidirectional changes in AMP-activated protein kinase activity.
Academic Article Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the alpha cardiac myosin heavy chain gene.
Academic Article Cardiac myosin binding protein C phosphorylation is cardioprotective.
Academic Article Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease.
Academic Article Myofilament mechanical performance is enhanced by R403Q myosin in mouse myocardium independent of sex.
Academic Article Glycogen storage diseases presenting as hypertrophic cardiomyopathy.
Academic Article Reduced cross-bridge dependent stiffness of skinned myocardium from mice lacking cardiac myosin binding protein-C.
Academic Article Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage.
Academic Article Comparison of two murine models of familial hypertrophic cardiomyopathy.
Academic Article Atrial natriuretic factor: assessment of its structure in atria and regulation of its biosynthesis with volume depletion.
Academic Article Exercise training improves cardiac function and attenuates arrhythmia in CPVT mice.
Academic Article The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms.
Academic Article A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease.
Academic Article Genome-wide identification of mouse congenital heart disease loci.
Academic Article Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis.
Academic Article E2F3 plays an essential role in cardiac development and function.
Academic Article Comparative proteomics profiling of a phospholamban mutant mouse model of dilated cardiomyopathy reveals progressive intracellular stress responses.
Academic Article AMP-activated protein kinase in the heart: role during health and disease.
Academic Article The T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction system.
Academic Article Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury.
Academic Article Truncations of titin causing dilated cardiomyopathy.
Academic Article A mouse model of familial hypertrophic cardiomyopathy.
Academic Article Modulation of atrial natriuretic factor by thyroid hormone: messenger ribonucleic acid and peptide levels in hypothyroid, euthyroid, and hyperthyroid rat atria and ventricles.
Academic Article Ouabain induces secretion of proatrial natriuretic factor by rat atrial cardiocytes.
Academic Article Proatrial natriuretic factor is phosphorylated by rat cardiocytes in culture.
Academic Article The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model.
Academic Article Differential cross-bridge kinetics of FHC myosin mutations R403Q and R453C in heterozygous mouse myocardium.
Academic Article A polymorphic modifier gene alters the hypertrophic response in a murine model of familial hypertrophic cardiomyopathy.
Academic Article A molecular basis for familial hypertrophic cardiomyopathy: a beta cardiac myosin heavy chain gene missense mutation.
Academic Article Somatic events modify hypertrophic cardiomyopathy pathology and link hypertrophy to arrhythmia.
Academic Article Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-ß.
Academic Article A serum protease cleaves proANF into a 14-kilodalton peptide and ANF.
Academic Article A molecular basis for familial hypertrophic cardiomyopathy: an alpha/beta cardiac myosin heavy chain hybrid gene.
Academic Article Identifying sarcomere gene mutations in hypertrophic cardiomyopathy: a personal history.
Academic Article Pheochromocytoma-induced cardiomyopathy is modulated by the synergistic effects of cell-secreted factors.
Academic Article Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis.
Academic Article Genetic causes of human heart failure.
Academic Article Cardiac myosin-binding protein-C phosphorylation and cardiac function.
Academic Article Polony multiplex analysis of gene expression (PMAGE) in mouse hypertrophic cardiomyopathy.
Academic Article Neonatal atria and ventricles secrete atrial natriuretic factor via tissue-specific secretory pathways.
Academic Article Myocardial fibrosis as an early manifestation of hypertrophic cardiomyopathy.
Academic Article An alpha-cardiac myosin heavy chain gene mutation impairs contraction and relaxation function of cardiac myocytes.
Academic Article Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy.
Concept Myocardium
Academic Article Spatial transcriptional profile of the chick and mouse endocardial cushions identify novel regulators of endocardial EMT in vitro.
Academic Article 5'RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy.
Academic Article A common genetic variant within SCN10A modulates cardiac SCN5A expression.
Academic Article Using next-generation RNA sequencing to examine ischemic changes induced by cold blood cardioplegia on the human left ventricular myocardium transcriptome.
Academic Article Haploinsufficiency of MYBPC3 exacerbates the development of hypertrophic cardiomyopathy in heterozygous mice.
Academic Article Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis.
Academic Article A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice.
Academic Article AAV9 Delivery of shRNA to the Mouse Heart.
Academic Article Reduced cross-bridge dependent stiffness of skinned myocardium from mice lacking cardiac myosin binding protein-C.
Grant SPECIALIZED CENTER OF RESEARCH IN HEART FAILURE
Grant MOLECULAR CAUSE OF FAMILIAL HYPERTROPHIC CARDIOMYOPATHY
Grant GENOMICS OF CARDIOVASCULAR DEVELOPMENT, ADAPTION
Academic Article Fulminant Myocarditis with Combination Immune Checkpoint Blockade.
Academic Article Loss of RNA expression and allele-specific expression associated with congenital heart disease.
Academic Article Preparation of rAAV9 to Overexpress or Knockdown Genes in Mouse Hearts.
Academic Article Early remodeling of repolarizing K+ currents in the aMHC403/+ mouse model of familial hypertrophic cardiomyopathy.
Academic Article IL-11 is a crucial determinant of cardiovascular fibrosis.
Academic Article Sex differences in gene expression in response to ischemia in the human left ventricular myocardium.
Academic Article Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin.
Academic Article Activin type II receptor signaling in cardiac aging and heart failure.
Academic Article Advances in the Genetic Basis and Pathogenesis of Sarcomere Cardiomyopathies.
Academic Article The Translational Landscape of the Human Heart.
Academic Article Marked Up-Regulation of ACE2 in Hearts of Patients With Obstructive Hypertrophic Cardiomyopathy: Implications for SARS-CoV-2-Mediated COVID-19.
Search Criteria
  • Myocardium
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.