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Reconstitution and characterization of a new desosaminyl transferase, EryCIII, from the erythromycin biosynthetic pathway.
Analysis of glycan polymers produced by peptidoglycan glycosyltransferases.
Transpeptidase-mediated incorporation of D-amino acids into bacterial peptidoglycan.
Vancomycin analogues active against vanA-resistant strains inhibit bacterial transglycosylase without binding substrate.
Initial characterization of novobiocic acid noviosyl transferase activity of NovM in biosynthesis of the antibiotic novobiocin.
Characterization of a regiospecific epivancosaminyl transferase GtfA and enzymatic reconstitution of the antibiotic chloroeremomycin.
Reconstitution of peptidoglycan cross-linking leads to improved fluorescent probes of cell wall synthesis.
Detection of lipid-linked peptidoglycan precursors by exploiting an unexpected transpeptidase reaction.
Lipid II overproduction allows direct assay of transpeptidase inhibition by ß-lactams.
Peptidoglycan Cross-Linking Preferences of Staphylococcus aureus Penicillin-Binding Proteins Have Implications for Treating MRSA Infections.
Identification of a Functionally Unique Family of Penicillin-Binding Proteins.