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One or more keywords matched the following items that are connected to Perrimon, Norbert
Item TypeName
Academic Article Serpentine proteins slither into the wingless and hedgehog fields.
Academic Article Recent advances in understanding signal transduction pathways in worms and flies.
Academic Article The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila.
Academic Article Signal transduction. Are there close encounters between signaling pathways?
Academic Article Developmental biology. Fishing for morphogens.
Academic Article Mechanism of inhibition of the Drosophila and mammalian EGF receptors by the transmembrane protein Kekkon 1.
Academic Article Evidence that stem cells reside in the adult Drosophila midgut epithelium.
Academic Article Specificity of receptor tyrosine kinase signaling pathways: lessons from Drosophila.
Academic Article Paradigms to study signal transduction pathways in Drosophila.
Academic Article Identifying loci required for follicular patterning using directed mosaics.
Academic Article A temporal switch in DER signaling controls the specification and differentiation of veins and interveins in the Drosophila wing.
Academic Article The JAK-STAT pathway in Drosophila.
Academic Article wingless signaling acts through zeste-white 3, the Drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate.
Academic Article Drosophila Jun relays the Jun amino-terminal kinase signal transduction pathway to the Decapentaplegic signal transduction pathway in regulating epithelial cell sheet movement.
Academic Article The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis.
Academic Article Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway.
Academic Article Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway.
Academic Article Polarity determination in the Drosophila eye: a novel role for unpaired and JAK/STAT signaling.
Academic Article Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling.
Academic Article Phosphorylation networks regulating JNK activity in diverse genetic backgrounds.
Academic Article The roles of JAK/STAT signaling in Drosophila immune responses.
Academic Article Sex determination: co-opted signals determine gender.
Academic Article Specificities of heparan sulphate proteoglycans in developmental processes.
Academic Article The Jak/STAT pathway in model organisms: emerging roles in cell movement.
Academic Article Slalom encodes an adenosine 3'-phosphate 5'-phosphosulfate transporter essential for development in Drosophila.
Academic Article BMP signaling is required for controlling somatic stem cell self-renewal in the Drosophila ovary.
Academic Article There must be 50 ways to rule the signal: the case of the Drosophila EGF receptor.
Academic Article Quantitative variations in the level of MAPK activity control patterning of the embryonic termini in Drosophila.
Academic Article Role of heparan sulfate proteoglycans in cell-cell signaling in Drosophila.
Academic Article The neurogenic genes egghead and brainiac define a novel signaling pathway essential for epithelial morphogenesis during Drosophila oogenesis.
Academic Article Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury.
Academic Article Notch modulates Wnt signalling by associating with Armadillo/beta-catenin and regulating its transcriptional activity.
Academic Article Extrusion and death of DPP/BMP-compromised epithelial cells in the developing Drosophila wing.
Academic Article Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion.
Academic Article FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging.
Academic Article Sequential activation of signaling pathways during innate immune responses in Drosophila.
Academic Article The PDGF/VEGF receptor controls blood cell survival in Drosophila.
Academic Article The roles of the Drosophila JAK/STAT pathway.
Academic Article Identification of autosomal regions involved in Drosophila Raf function.
Academic Article Dual role of the fringe connection gene in both heparan sulphate and fringe-dependent signalling events.
Academic Article corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso.
Academic Article Rasp, a putative transmembrane acyltransferase, is required for Hedgehog signaling.
Academic Article Roles of myosin phosphatase during Drosophila development.
Academic Article GFP reporters detect the activation of the Drosophila JAK/STAT pathway in vivo.
Academic Article Genetic screening for signal transduction in the era of network biology.
Academic Article Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan.
Academic Article Genetic and molecular analyses of mutations involved in Drosophila raf signal transduction.
Academic Article Dissection of the Torso signal transduction pathway in Drosophila.
Academic Article Serine/threonine protein kinases in Drosophila.
Academic Article Integration of Insulin receptor/Foxo signaling and dMyc activity during muscle growth regulates body size in Drosophila.
Academic Article Signalling pathways initiated by receptor protein tyrosine kinases in Drosophila.
Academic Article Interaction between Wingless and Notch signaling pathways mediated by dishevelled.
Academic Article A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway.
Academic Article The latest in signal transduction, 1999. Specificity in Signal Transduction, Keystone, Colorado, USA, 9-14 April 1999.
Academic Article The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration.
Academic Article Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20.
Academic Article Genome-wide RNAi screen for host factors required for intracellular bacterial infection.
Academic Article Functional genomic analysis of the Wnt-wingless signaling pathway.
Academic Article Norbert Perrimon.
Academic Article Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways.
Academic Article A genome-wide transgenic resource for conditional expression of Drosophila microRNAs.
Academic Article The genetic basis of patterned baldness in Drosophila.
Academic Article Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development.
Academic Article Doublesex surprises.
Academic Article Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila.
Academic Article Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper.
Academic Article Use of a label-free quantitative platform based on MS/MS average TIC to calculate dynamics of protein complexes in insulin signaling.
Academic Article Functional screening identifies miR-315 as a potent activator of Wingless signaling.
Academic Article Functional binding of secreted molecules to heparan sulfate proteoglycans in Drosophila.
Academic Article Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless.
Academic Article Investigation of leading edge formation at the interface of amnioserosa and dorsal ectoderm in the Drosophila embryo.
Academic Article Hedgehog signal transduction: recent findings.
Academic Article Heparan sulfate proteoglycan modulation of developmental signaling in Drosophila.
Academic Article Apicobasal polarization: epithelial form and function.
Academic Article Heparan sulphate proteoglycans: the sweet side of development.
Academic Article The torso receptor protein-tyrosine kinase signaling pathway: an endless story.
Academic Article The porcupine gene is required for wingless autoregulation in Drosophila.
Academic Article Quantitative morphological signatures define local signaling networks regulating cell morphology.
Academic Article Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer.
Academic Article Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled.
Academic Article Developmental biology. Sending all the right signals.
Academic Article The promise and perils of Wnt signaling through beta-catenin.
Academic Article Frizzled signaling and the developmental control of cell polarity.
Academic Article The homeobox transcription factor cut coordinates patterning and growth during Drosophila airway remodeling.
Academic Article Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila.
Academic Article The transmembrane molecule kekkon 1 acts in a feedback loop to negatively regulate the activity of the Drosophila EGF receptor during oogenesis.
Academic Article The cell adhesion molecule Echinoid defines a new pathway that antagonizes the Drosophila EGF receptor signaling pathway.
Academic Article Mechanism of activation of the Drosophila EGF Receptor by the TGFalpha ligand Gurken during oogenesis.
Academic Article Role of heparan sulfate proteoglycans in cell signaling and cancer.
Academic Article Wingless, hedgehog and heparan sulfate proteoglycans.
Academic Article The Wingless morphogen gradient is established by the cooperative action of Frizzled and Heparan Sulfate Proteoglycan receptors.
Academic Article The Drosophila 14-3-3 protein Leonardo enhances Torso signaling through D-Raf in a Ras 1-dependent manner.
Academic Article Drosophila wingless: a paradigm for the function and mechanism of Wnt signaling.
Academic Article The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal.
Academic Article Developmental biology: Our fly cousins' gut.
Academic Article The Drosophila JNK pathway controls the morphogenesis of the egg dorsal appendages and micropyle.
Academic Article The transcriptional diversity of 25 Drosophila cell lines.
Academic Article The torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway.
Academic Article The molecular genetics of tail development in Drosophila melanogaster.
Academic Article The four-jointed gene is required in the Drosophila eye for ommatidial polarity specification.
Academic Article CKA, a novel multidomain protein, regulates the JUN N-terminal kinase signal transduction pathway in Drosophila.
Academic Article Inference of RhoGAP/GTPase regulation using single-cell morphological data from a combinatorial RNAi screen.
Academic Article dishevelled and armadillo act in the wingless signalling pathway in Drosophila.
Academic Article Signaling mechanisms controlling cell fate and embryonic patterning.
Academic Article Function of the ETS transcription factor Yan in border cell migration.
Academic Article Developmental and molecular characterization of mutations in the Drosophila-raf serine/threonine protein kinase.
Academic Article Signal transduction in the early Drosophila embryo: when genetics meets biochemistry.
Academic Article Components of wingless signalling in Drosophila.
Academic Article Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs.
Academic Article Hedgehog and beyond.
Academic Article A temperature-sensitive MEK mutation demonstrates the conservation of the signaling pathways activated by receptor tyrosine kinases.
Academic Article Drosophila terminal structure development is regulated by the compensatory activities of positive and negative phosphotyrosine signaling sites on the Torso RTK.
Academic Article Raf acts downstream of the EGF receptor to determine dorsoventral polarity during Drosophila oogenesis.
Academic Article Control of cell fate determination by p21ras/Ras1, an essential component of torso signaling in Drosophila.
Academic Article Mammalian and Drosophila blood: JAK of all trades?
Academic Article Highlights of the 1998 Wnt meeting, Cambridge, MA, January 9-11.
Academic Article The torso pathway in Drosophila: lessons on receptor tyrosine kinase signaling and pattern formation.
Academic Article The torso pathway in Drosophila: a model system to study receptor tyrosine kinase signal transduction.
Academic Article Cellular phenotype recognition for high-content RNA interference genome-wide screening.
Academic Article Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling.
Academic Article wingless refines its own expression domain on the Drosophila wing margin.
Academic Article Brainiac and fringe are similar pioneer proteins that impart specificity to notch signaling during Drosophila development.
Academic Article Synergistic activities of multiple phosphotyrosine residues mediate full signaling from the Drosophila Torso receptor tyrosine kinase.
Academic Article Developmental roles of heparan sulfate proteoglycans in Drosophila.
Academic Article Drosophila Wnt/Fz pathways.
Concept Signal Transduction
Academic Article The circadian clock gates the intestinal stem cell regenerative state.
Academic Article Receptor tyrosine kinases in Drosophila development.
Academic Article Ecdysone signaling at metamorphosis triggers apoptosis of Drosophila abdominal muscles.
Academic Article Muscle mitohormesis promotes longevity via systemic repression of insulin signaling.
Academic Article Defining the interorgan communication network: systemic coordination of organismal cellular processes under homeostasis and localized stress.
Academic Article Integrating protein-protein interaction networks with phenotypes reveals signs of interactions.
Academic Article Mechanisms of muscle growth and atrophy in mammals and Drosophila.
Academic Article A regulatory network of Drosophila germline stem cell self-renewal.
Academic Article Visualizing and manipulating temporal signaling dynamics with fluorescence-based tools.
Academic Article A rapid genome-wide microRNA screen identifies miR-14 as a modulator of Hedgehog signaling.
Academic Article Spatial and temporal organization of signaling pathways.
Academic Article A systems-level interrogation identifies regulators of Drosophila blood cell number and survival.
Academic Article Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch.
Academic Article Stress signaling between organs in metazoa.
Academic Article The Atg1-Tor pathway regulates yolk catabolism in Drosophila embryos.
Academic Article Toward a Systems Understanding of Signaling Pathway Function.
Academic Article The torso pathway in Drosophila: a model system to study receptor tyrosine kinase signal transduction.
Academic Article Coordinated control of Notch/Delta signalling and cell cycle progression drives lateral inhibition-mediated tissue patterning.
Academic Article Oncogenic transformation of Drosophila somatic cells induces a functional piRNA pathway.
Academic Article Mapping signaling pathway cross-talk in Drosophila cells.
Grant THE INT-1 SIGNAL TRANSDUCTION PATHWAY
Grant CONFERENCE ON SPECIFICITY IN SIGNAL TRANSDUCTION
Grant Network Topology in Cell Signaling
Grant Network analysis of Signal Transduction
Grant Development of Validated Drosophila in vivo RNAi Models of Human Diseases
Grant Conference on Cell Polarity &Asymmetric Cell Divisions
Grant Proliferative control of normal &oncogenically transformed stem cells in vivo
Grant Development of Validated Drosophila in vivo RNAi Models of Human Diseases
Academic Article An Integrative Analysis of the InR/PI3K/Akt Network Identifies the Dynamic Response to Insulin Signaling.
Academic Article Interorgan Communication Pathways in Physiology: Focus on Drosophila.
Academic Article miR-263a Regulates ENaC to Maintain Osmotic and Intestinal Stem Cell Homeostasis in Drosophila.
Academic Article Midgut-Derived Activin Regulates Glucagon-like Action in the Fat Body and Glycemic Control.
Academic Article Oxidative stress induces stem cell proliferation via TRPA1/RyR-mediated Ca2+ signaling in the Drosophila midgut.
Academic Article Open questions: completing the parts list and finding the integrating signals.
Academic Article The TORC1-Regulated CPA Complex Rewires an RNA Processing Network to Drive Autophagy and Metabolic Reprogramming.
Academic Article Endocrine Regulation of Energy Balance by Drosophila TGF-ß/Activins.
Academic Article A Membrane Transporter Is Required for Steroid Hormone Uptake in Drosophila.
Academic Article iProteinDB: An Integrative Database of Drosophila Post-translational Modifications.
Academic Article Drosophila intestinal stem and progenitor cells are major sources and regulators of homeostatic niche signals.
Academic Article Intestinal Stem Cells Exhibit Conditional Circadian Clock Function.
Academic Article Mechanosensitive channels and their functions in stem cell differentiation.
Academic Article Tumor-Derived Ligands Trigger Tumor Growth and Host Wasting via Differential MEK Activation.
Academic Article The Septate Junction Protein Tsp2A Restricts Intestinal Stem Cell Activity via Endocytic Regulation of aPKC and Hippo Signaling.
Academic Article A role for actomyosin contractility in Notch signaling.
Academic Article Interspecies analysis of MYC targets identifies tRNA synthetases as mediators of growth and survival in MYC-overexpressing cells.
Academic Article Regulation of insulin and adipokinetic hormone/glucagon production in flies.
Academic Article HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species.
Academic Article A single-cell survey of Drosophila blood.
Academic Article A Drosophila model of oral peptide therapeutics for adult intestinal stem cell tumors.
Academic Article Drosophila PDGF/VEGF signaling from muscles to hepatocyte-like cells protects against obesity.
Academic Article Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response.
Academic Article Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells.
Academic Article Defining cell types and lineage in the Drosophila midgut using single cell transcriptomics.
Academic Article mTORC1-chaperonin CCT signaling regulates m6A RNA methylation to suppress autophagy.
Academic Article mTORC1 promotes cell growth via m6A-dependent mRNA degradation.
Search Criteria
  • Pathway Signal Transduction
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.